CN108159085A - A kind of probiotics ulcer patch - Google Patents
A kind of probiotics ulcer patch Download PDFInfo
- Publication number
- CN108159085A CN108159085A CN201810059975.XA CN201810059975A CN108159085A CN 108159085 A CN108159085 A CN 108159085A CN 201810059975 A CN201810059975 A CN 201810059975A CN 108159085 A CN108159085 A CN 108159085A
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- China
- Prior art keywords
- ulcer
- patch
- probiotics
- probiotic powder
- types
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a kind of probiotics ulcer patch, directly using probiotics in chronic ulcer;It is formed a complete set of by A types ulcer patch and Type B ulcer patch, the A types ulcer patch and Type B ulcer patch are made respectively of the probiotic powder of sterile absorbent gauze (or other dressing) and coating thereon by vacuum sealed package;The probiotic powder that the A types ulcer is sticked is by Bifidobacterium, lactobacillus acidophilus, bacillus subtilis with 2~3:2:1 weight ratio compatibility;The probiotic powder that the Type B ulcer is sticked is by Bifidobacterium, lactobacillus acidophilus with 1~2:1 weight ratio compatibility.By probiotics for chronic wounds wound healing, the long-term ulcer wound not more for the treatment of effectively alleviates the slight illness of patient, obtains the effect of fine the present invention.
Description
Technical field
The invention belongs to field of medical materials, and in particular to a kind of to treat the probiotics ulcer for being difficult to the chronic wounds to heal
Patch.
Background technology
Chronic wounds are generally difficult to the wound to heal, are the severe health problems that modern society faces, especially to old
It for year crowd, can last for several years and disunion sometimes, but we treat it without the method got well.It is most of for slow at present
Property wound research focus on improve antiseptic dressing to prevent to infect, effect is undesirable.
It is understood that the body of the mankind is covered by bacterium, i.e. normal flora described in us, the work in alimentary canal
With it is widely known that and live bacterium on the skin, it is that we study and few.Although the Bacteria Culture of infected wound pathogenic bacteria
+ drug sensitive test has become the routine clinical scope of examination, but beneficial bacterium does not draw attention to the Healing of wound.There is research people
Member (Matthew Hartman, the senior researcher of Univ Manchester UK's Cure Study On fund) has found that skin bacterium is being hindered
It is played an important role in mouth healing.
The present inventor combines the various surface of a wound that more than two decades curative activity encounters, the processing treatment of wound, consults big
Data of literatures is measured, is licked from animal and wipes wound and gain enlightenment in healing, be bold in innovation, invented a kind of probiotics ulcer
Patch is not cured ulcer wound for treating, obtains the effect of fine for a long time.
Invention content
Goal of the invention:The defects of for existing method, spy develop a kind of probiotics ulcer patch, long-term more not routed for treating
Ulcer wound mitigates the slight illness of patient.
Technical solution:The purpose of the present invention is what is realized by following technical proposals:
A kind of probiotics ulcer patch, directly using probiotics in chronic ulcer, the long-term ulcer not more for the treatment of;By A
Type ulcer is pasted and Type B ulcer patch forms a complete set of, A types ulcer patch and Type B ulcer patch respectively by sterile absorbent gauze (or
Other dressing) and coating probiotic powder thereon be made by vacuum sealed package;The probiotic powder that the A types ulcer is sticked
By Bifidobacterium, lactobacillus acidophilus, bacillus subtilis with 2~3:2:1 weight ratio compatibility;What the Type B ulcer was sticked
Probiotic powder is by Bifidobacterium, lactobacillus acidophilus with 1~2:1 weight ratio compatibility.
Preferably, the probiotic powder is powdery solid, about contains 100,000,000 viable counts in the finished product probiotic powder per 1g;
Preferably, it is about 0.1g that each probiotic powder pastes the weight on effective area every square centimeter coated in ulcer, about
Containing 0.1 hundred million certain viable counts, then the probiotic powder total weight that the A types ulcer is pasted on effective area every square centimeter is about
0.5~0.6g, containing about 0.5~0.6 hundred million viable counts;The Type B ulcer pastes the probiotic powder on effective area every square centimeter
Total weight is about 0.2~0.3g, containing about 0.2~0.3 hundred million viable counts.
Basic principle:L, non-pathogenic probiotics is not pathogenic.2nd, probiotics flourish can inhibit pathogenic bacteria and opportunistic
The flourish of bacterium.3rd, probiotics can generate antibiotic, protect wound, it is not necessary to reuse antibiosis extract for treating.4th, probiotics can produce
Some raw nutrients promote human body cell growth to accelerate wound healing.5th, probiotics decomposable asymmetric choice net removal surface of a wound slough, favorably
The fresh granulation tissue growth of the surface of a wound.6th, sterile absorbent gauze (or other dressing) absorbs surface of a wound exudation and metabolic waste, keeps wound
It dries in face.7th, A types ulcer patch is for purulence tongue necrosis phase ulcer surface, and Type B ulcer patch is for the new raw meat after A types ulcer is used to paste
The ulcer surface of bud growth.
Application method:Probiotics ulcer patch is removed into vacuum packaging, then will apply spreading on one side for probiotic powder
The surface of a wound is cemented with adhesive plaster or gauze, the next day replace;1 month as a treatment course.
The advantages of the present invention:The present invention for chronic wounds wound healing, treats probiotics for a long time not
More ulcer wound effectively alleviates the slight illness of patient, obtains the effect of fine.
Specific embodiment
To make the objectives, technical solutions, and advantages of the present invention clearer, with reference to specific embodiment to the present invention
It is described in detail.
A kind of probiotics ulcer patch, directly using probiotics in chronic ulcer, the long-term ulcer not more for the treatment of;By A
Type ulcer is pasted and Type B ulcer patch forms a complete set of, A types ulcer patch and Type B ulcer patch respectively by sterile absorbent gauze (or
Other dressing) and coating probiotic powder thereon be made by vacuum sealed package;The probiotic powder that the A types ulcer is sticked
By Bifidobacterium, lactobacillus acidophilus, bacillus subtilis with 2~3:2:1 weight ratio compatibility;What the Type B ulcer was sticked
Probiotic powder is by Bifidobacterium, lactobacillus acidophilus with 1~2:1 weight ratio compatibility.
The probiotic powder is powdery solid, about contains 100,000,000 viable counts in the finished product probiotic powder per 1g;
It is about 0.1g that each probiotic powder pastes the weight on effective area every square centimeter coated in ulcer, containing about 0.1 hundred million
Certain a viable count, then the probiotic powder total weight that the A types ulcer pastes on effective area every square centimeter is about 0.5~
0.6g, containing about 0.5~0.6 hundred million viable counts;The Type B ulcer pastes the probiotic powder total weight on effective area every square centimeter
About 0.2~0.3g, containing about 0.2~0.3 hundred million viable counts.
Embodiment:
Case one:Yao, Huainan, Anhui people, man, 81 years old, Late-stage diabetic, foot gangrene was festered, use at the ulcer described in
The wrapping of probiotics ulcer patch, dressing, two weeks or so, it is most of to heal.
Case two:Zhang more than 60 years old, varix of lower limb gaskin ulcer elephantiasis more than ten years, does not feel any better, in ulcer
Place's probiotics ulcer patch wrapping, dressing, it is one month or so, basic to heal.
Case three:Liu, female, more than 90 years old, long-term bed and cause pressure sore at stern hip, with the probiotics ulcer at ulcer
Patch wrapping, dressing, one month or so, are improved at ulcer, more much effective than other dressings.
The foregoing is merely presently preferred embodiments of the present invention and related case, is not intended to limit the invention, all in this hair
All any modification, equivalent and improvement made within bright spirit and principle etc., be all contained in protection scope of the present invention it
It is interior.
Claims (3)
1. a kind of probiotics ulcer patch, which is characterized in that directly using probiotics in chronic ulcer;By A types ulcer patch and B
Type ulcer patch forms a complete set of, and the A types ulcer patch and Type B ulcer patch by sterile absorbent gauze and apply thereon respectively
Probiotic powder is made by vacuum sealed package;The probiotic powder that the A types ulcer is sticked by Bifidobacterium, lactobacillus acidophilus,
Bacillus subtilis is with 2~3:2:1 weight ratio compatibility;The probiotic powder that the Type B ulcer is sticked is by Bifidobacterium, acidophilus
Lactobacillus is with 1~2:1 weight ratio compatibility.
2. probiotics ulcer patch according to claim 1, which is characterized in that the probiotic powder is powdery solid, per 1g
Finished product probiotic powder in about contain 100,000,000 viable counts.
3. probiotics ulcer patch according to claim 1, which is characterized in that each probiotic powder is often put down coated in ulcer patch
Weight on square centimetre of effective area is about 0.1g, containing about 0.1 hundred million certain viable counts, then the A types ulcer pastes every square li
Probiotic powder total weight on rice effective area is about 0.5~0.6g, containing about 0.5~0.6 hundred million viable counts;The Type B ulcer
The probiotic powder total weight pasted on effective area every square centimeter is about 0.2~0.3g, containing about 0.2~0.3 hundred million viable counts.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201810059975.XA CN108159085A (en) | 2018-01-22 | 2018-01-22 | A kind of probiotics ulcer patch |
Applications Claiming Priority (1)
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CN201810059975.XA CN108159085A (en) | 2018-01-22 | 2018-01-22 | A kind of probiotics ulcer patch |
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CN108159085A true CN108159085A (en) | 2018-06-15 |
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CN201810059975.XA Pending CN108159085A (en) | 2018-01-22 | 2018-01-22 | A kind of probiotics ulcer patch |
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Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104382955A (en) * | 2014-12-02 | 2015-03-04 | 汤臣倍健股份有限公司 | Composition, application thereof and health product |
CN104825570A (en) * | 2015-05-20 | 2015-08-12 | 杨克西 | Composition for inhibiting helicobacter pylori and application of composition |
-
2018
- 2018-01-22 CN CN201810059975.XA patent/CN108159085A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104382955A (en) * | 2014-12-02 | 2015-03-04 | 汤臣倍健股份有限公司 | Composition, application thereof and health product |
CN104825570A (en) * | 2015-05-20 | 2015-08-12 | 杨克西 | Composition for inhibiting helicobacter pylori and application of composition |
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PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
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RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180615 |
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RJ01 | Rejection of invention patent application after publication |