CN108144033A - 一种治疗颈椎腰腿痛及中风后遗症的外用黑膏药 - Google Patents

一种治疗颈椎腰腿痛及中风后遗症的外用黑膏药 Download PDF

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CN108144033A
CN108144033A CN201810145482.8A CN201810145482A CN108144033A CN 108144033 A CN108144033 A CN 108144033A CN 201810145482 A CN201810145482 A CN 201810145482A CN 108144033 A CN108144033 A CN 108144033A
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radix
oil
groups
rhizoma
medicine
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潘小红
扈麟
潘胡林
张艳艳
张礼红
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Abstract

本发明公开了一种治疗颈椎腰腿痛及中风后遗症的外用黑膏药,由A、B、C三组制方组成,A组药由B组药和C组药组成,A、B、C三组药既可以合成制膏,还可以分开制膏;本发明提供的黑膏药见效迅速,疗效明显,无毒副作用,使用方便,有舒筋活血,温经散寒,袪风止痛,调和气血等功效,为治疗颈椎病、肩周炎、治疗腰椎间盘突出、中风后遗症、腿痛及跌打损伤的外用膏药,见效迅速,疗效明显,无毒副作用,使用方便,适用于治颈椎病、肩周炎、治疗腰椎间盘突出、腿痛及跌打损伤、腰腿痛、风湿性关节炎、中风后遗症、骨质增生及腰肌劳损的缓解和治疗。

Description

一种治疗颈椎腰腿痛及中风后遗症的外用黑膏药
技术领域
本发明涉及中药制剂技术领域,具体涉及一种治疗颈椎腰腿痛及中风后遗症的外用黑膏药。
背景技术
颈、肩、腰、腿痛、风湿关节炎、颈椎病、肩周炎、骨质增生、腰肌劳损、跌打损伤、腰椎间盘突出等疾病,其发病主体主要是青壮年( 20~50岁) ,平均年龄 40 岁左右,并有低龄化趋势,文献报道,我国颈椎病的发病率为17.3%,腰椎间盘突出症的发病率已达15.2% ,肩周炎发病率为2~5%,在世界卫生组织公布的“全球十大顽症”中,颈椎病排序第二,腰椎间盘突出症为危害人类健康的“第二杀手”,病程长、迁延不愈、并发症多、复发率高的特性,尤其是因腰椎间盘突出而丧失工作能力的人口比例持续上升,给患者、家庭、社会带来极大负担。
目前治疗方法有物理疗法,外用药,内服中药、非抗体类抗炎止痛药,手术疗法,但各种疗法均有弊端,物理疗法只是局部治疗,而不能从整体上进行调整,效果不够理想;内服药毒性大,不宜久服;手术疗法,创伤大,危险性高,患者不易接受。所以,迫切需要疗效确切,毒副作用小,宜于长期使用的药物,因此人们需要开发更多有效的配方,本发明提供了一种使用方便,疗效确切,价格低廉,有较好治疗作用的一种外用药膏及其制备方法。
发明内容
本发明旨在提供一种治疗治颈椎病、肩周炎、治疗腰椎间盘突出、腿痛及跌打损伤、腰腿痛、中风后遗症、风湿性关节炎及腰肌劳损的外用膏药,以增加治疗腰椎间盘突出的药物品种,使之能够为人们的健康服务,提供了一种治疗颈椎腰腿痛及中风后遗症的外用黑膏药。
本发明采用如下技术方案实现其发明目的:一种治疗颈椎腰腿痛及中风后遗症的外用黑膏药,由A、B、C三组制方组成,A组药由B组药和C组药组成,A、B、C三组药既可以合成制膏,还可以分开制膏;
其中A组由38味药组成,其组分及质量配比为: 荆芥15~25,防风1~18,千年健15~25,当归5~15,鸡血藤4~12,肉桂4~12,苍耳子3~12,木瓜6~15,透骨草20~40,追地风3~12,元胡1~5,桑枝6~15,海风藤20~40,石南藤20~40,羌活3~12,独活3~9,红花3~12,赤芍3~9,桃仁3~9,川芎10~22,白微1~6,去油的乳香2~10,去油的没药2~10,牛膝1~9,丁香2~10,冰片10~30,三分三0.1~5,生马钱子6~15,生川乌1~6,生草乌1~6,生南星1~6,五加皮1~6,细辛0.3~2.5,干姜1~6,杜仲1~6,三七0.2~4,无患子0.2~4,樟脑15~35,单位为份;
B组由25味药材组成,其组分及质量配比为: 荆芥15~25,防风1~18,千年健15~25,当归5~15,鸡血藤4~12,肉桂4~12,苍耳子3~12,木瓜6~15,透骨草3~10,追地风3~12,元胡1~5,桑枝6~15,海风藤20~40,石南藤20~40,羌活3~12,独活3~9,红花3~12,赤芍3~9,桃仁3~9,川芎10~22,白微1~6,去油的乳香2~10,去油的没药2~10,牛膝1~9,丁香2~10,单位为份;
C组由13味药材组成,其组分及质量配比为:冰片10~30,三分三0.1~5,生马钱子6~15,生川乌1~6,生草乌1~6,生南星1~6,五加皮1~6,细辛0.3~2.5,干姜1~6,杜仲1~6,三七0.2~4,无患子0.2~4,樟脑15~35,单位为份。
本治疗颈椎腰腿痛及中风后遗症的外用黑膏药的制备流程为:
①原材料预处理:取配方的38味药材分别洗净,用热风烘干,所有药磨成60目粉末;
②药料的提取:取荆芥,防风,千年健,当归,鸡血藤,肉桂,苍耳子,木瓜,透骨草,追地风,元胡,桑枝,海风藤,石南藤,羌活,独活,红花,赤芍,桃仁,川芎,白微,去油的乳香,去油的没药,牛膝,丁香放入8000~33000ml麻油或豆油中泡7~9天后置锅内,加热并不断搅拌,用文火炸枯使诸药成炭直至药料炸至表面深褐色内部焦黄为度,此时温度可达220度,炸好后可用铁丝筛捞去药渣,去渣后的油为药油;
③炼油:取上述纯药油继续熬炼,待药油温度上升到320度后改用中火;炼油的火候:一是看温度计,达到规定温度;二是看油烟,开始为浅青色,渐为黑而浓,进而为白色浓烟,无风时白烟直上;三是看油花:沸腾开始时,油花多在锅壁周边附近,当油花向锅中央聚集时为度;四是看滴水成珠:取少许药油滴于水中,不散开成珠状为度;
④下丹:药油炼成后,离火下丹,一般500克油可加200克左右黄丹,黄丹在下前先干燥并过100目筛,少量加黄丹,用竹筷边加边搅动,一定要向同方向搅拌;搅成粘稠的膏体,膏药不粘手,拉丝不断为好,过硬则老,过粘则嫩;搅拌均匀后立即倒入冷水中浸泡十五天,每天换水二次去火毒;
⑤摊膏药:取下丹后的油膏稍加温至100度左右兑入冰片,生马钱子,生川乌,生草乌,生南星,五加皮,细辛,干姜,杜仲,三七,无患子,三分三,樟脑细粉拌匀,用竹筷团起,随纸布大小,以竹筷点纸布之中心作顺时针摊一周,密封保存备用。
本发明的外用黑膏药的使用方法是外敷,每次取制成的膏药贴患处。
有益效果:本发明提供的黑膏药见效迅速,疗效明显,无毒副作用,使用方便,有舒筋活血,温经散寒,袪风止痛,调和气血等功效,为治疗颈椎病、肩周炎、治疗腰椎间盘突出、中风后遗症、腿痛及跌打损伤的外用膏药,见效迅速,疗效明显,无毒副作用,使用方便,适用于治颈椎病、肩周炎、治疗腰椎间盘突出、腿痛及跌打损伤、腰腿痛、风湿性关节炎、中风后遗症、骨质增生及腰肌劳损的缓解和治疗。
具体实施方式
实施例1:
由发明内容可知,一种治疗颈椎腰腿痛及中风后遗症的外用黑膏药,由A、B、C三组制方组成,A组药由B组药和C组药组成,A、B、C三组药既可以合成制膏,还可以分开制膏;
其中A组由38味药组成,其组分及质量配比为: 荆芥15~25,防风1~18,千年健15~25,当归5~15,鸡血藤4~12,肉桂4~12,苍耳子3~12,木瓜6~15,透骨草20~40,追地风3~12,元胡1~5,桑枝6~15,海风藤20~40,石南藤20~40,羌活3~12,独活3~9,红花3~12,赤芍3~9,桃仁3~9,川芎10~22,白微1~6,去油的乳香2~10,去油的没药2~10,牛膝1~9,丁香2~10,冰片10~30,三分三0.1~5,生马钱子6~15,生川乌1~6,生草乌1~6,生南星1~6,五加皮1~6,细辛0.3~2.5,干姜1~6,杜仲1~6,三七0.2~4,无患子0.2~4,樟脑15~35,单位为份;
B组由25味药材组成,其组分及质量配比为: 荆芥15~25,防风1~18,千年健15~25,当归5~15,鸡血藤4~12,肉桂4~12,苍耳子3~12,木瓜6~15,透骨草3~10,追地风3~12,元胡1~5,桑枝6~15,海风藤20~40,石南藤20~40,羌活3~12,独活3~9,红花3~12,赤芍3~9,桃仁3~9,川芎10~22,白微1~6,去油的乳香2~10,去油的没药2~10,牛膝1~9,丁香2~10,单位为份;
C组由13味药材组成,其组分及质量配比为:冰片10~30,三分三0.1~5,生马钱子6~15,生川乌1~6,生草乌1~6,生南星1~6,五加皮1~6,细辛0.3~2.5,干姜1~6,杜仲1~6,三七0.2~4,无患子0.2~4,樟脑15~35,单位为份。
本治疗颈椎腰腿痛及中风后遗症的外用黑膏药的制备流程为:
①原材料预处理:取配方的38味药材分别洗净,用热风烘干,所有药磨成60目粉末;
②药料的提取:取荆芥,防风,千年健,当归,鸡血藤,肉桂,苍耳子,木瓜,透骨草,追地风,元胡,桑枝,海风藤,石南藤,羌活,独活,红花,赤芍,桃仁,川芎,白微,去油的乳香,去油的没药,牛膝,丁香放入8000~33000ml麻油或豆油中泡7~9天后置锅内,加热并不断搅拌,用文火炸枯使诸药成炭直至药料炸至表面深褐色内部焦黄为度,此时温度可达220度,炸好后可用铁丝筛捞去药渣,去渣后的油为药油;
③炼油:取上述纯药油继续熬炼,待药油温度上升到320度后改用中火;炼油的火候:一是看温度计,达到规定温度;二是看油烟,开始为浅青色,渐为黑而浓,进而为白色浓烟,无风时白烟直上;三是看油花:沸腾开始时,油花多在锅壁周边附近,当油花向锅中央聚集时为度;四是看滴水成珠:取少许药油滴于水中,不散开成珠状为度;
④下丹:药油炼成后,离火下丹,一般500克油可加200克左右黄丹,黄丹在下前先干燥并过100目筛,少量加黄丹,用竹筷边加边搅动,一定要向同方向搅拌;搅成粘稠的膏体,膏药不粘手,拉丝不断为好,过硬则老,过粘则嫩;搅拌均匀后立即倒入冷水中浸泡十五天,每天换水二次去火毒;
⑤摊膏药:取下丹后的油膏稍加温至100度左右兑入冰片,生马钱子,生川乌,生草乌,生南星,五加皮,细辛,干姜,杜仲,三七,无患子,三分三,樟脑细粉拌匀,用竹筷团起,随纸布大小,以竹筷点纸布之中心作顺时针摊一周,密封保存备用。
本发明所选用的药材的药理学基础为:1、荆芥:辛,微温。归肺、肝经;解表散风,头痛。见《中国药典2015年》(一部)第232页。
2、海风藤:辛、苦,微温。归肝经;祛风湿,通经络,止痹痛。用于风寒湿搏,肢节疼痛,筋脉拘挛,屈伸不利。见《中国药典2015年》(一部)第293页。
3、丁香:辛,温。归脾、胃、肺、肾经;补肾助阳。心腹冷痛,肾虚阳痿。注意:不宜与郁金同用。见《中国药典2015年》(一部)第4页。
4、防风:辛、甘,微温。归膀胱、肝、脾经。祛风解表,胜湿止痛,止痉。用于风湿痹痛,风瘆瘙痒。见《中国药典2015年》(一部)第149页。
5、石南藤:辛,温。归肝、脾经;祛风湿,通经络。用于风寒湿痹,筋骨疼痛,腰痛。见湖南省中药饮片炮制规范(2010年版)第363页。
6、冰片:辛、苦,微寒。归心、脾、肺经。开窍醒神,清热止痛。用于惊厥,中风痰厥,胸痹心痛。注意:孕妇慎用。见《中国药典2015年》(一部)第146页。
7、千年健:苦、辛,温。归肝、肾经。祛风湿,壮筋骨。用于风寒湿痹,腰膝冷痛,拘挛麻木,筋骨痿软。见《中国药典2015年》(一部)第33页。
8、马钱子:苦,温;有大毒。归肝、脾经。通络止痛,散结消肿。用于跌打损伤,骨折肿痛,风湿顽痹,麻木瘫痪。注意:孕妇禁用;运动员慎用;有毒成分能经皮肤吸收,外用不宜大面积涂敷。见《中国药典2015年》(一部)第51页。
9、当归:甘、辛,温。归肝、心、脾经。补血活血。用于风湿痹痛,跌扑损伤,痈疽疮疡,肠燥便秘。酒当归活血通经。用于风湿痹痛,跌扑损饬。见《中国药典2015年》(一部)第134页。
10、独活:辛、苦,微温。归肾、膀胱经。祛风除湿,通痹止痛。用于风寒湿痹,腰膝疼痛。见《中国药典2015年》(一部)第263页。
11、川乌:辛、苦,热;有大毒。归心、肝、肾、脾经。祛风除湿,温经止痛。用于风寒湿痹,关节疼痛。注意:孕妇禁用。见《中国药典2015年》(一部)第39页。
12、鸡血藤:苦、甘,温。归肝、肾经。活血补血,舒筋活络。用于风湿痹痛,麻木瘫痰。见《中国药典2015年》(一部)第194页。
13、红花:辛,温。归心、肝经。活血通经,散瘀止痛。用于胸胁剌痛,跌扑损伤。注意:孕妇慎用。见《中国药典2015年》(一部)第151页。
14、草乌:辛、苦,热;有大毒。归心、肝、肾、脾经。祛风除湿,温经止痛。用于风寒湿痹,关节疼痛。注意:孕妇禁用。见《中国药典2015年》(一部)第236页。
15、肉桂:辛、甘,大热。归肾、脾、心、肝经。散寒止痛,温通经脉 , 用于腰膝冷痛,眩晕目赤,心窺冷痛,,寒痛腹痛。注窻:有出血倾向者及孕妇慎用。见《中国药典2015年》(一部)第137页。
16、天南星:苦、辛,温;有毒。归肺、肝、脾经。散结消肿。注意:孕妇慎用。
17、苍耳子:辛、苦,温;有毒。归肺经。散风寒,祛风湿。用于风寒头痛,湿痹拘挛。见《中国药典2015年》(一部)第162页。
18、桃仁:苦、甘,平。归心、肝、大肠经。活血祛瘀。用于跌扑损伤。见《中国药典2015年》(一部)第278页。
19、木瓜:酸,温。归肝、脾经。舒筋活络。用于湿痹拘挛,腰膝关节酸重疼痛,转筋挛痛。见《中国药典2015年》(一部)第61页。
20、川芎:辛,温。归肝、胆、心包经。活血行气,祛风止痛。用于胸痹心痛,胸胁刺痛,跌扑肿痛,头痛,风湿痹痛。见《中国药典2015年》(一部)第41页。
21、五加皮:辛、苦,温。 归肝、肾经。祛风除湿,补益肝肾,强筋壮骨。用于风湿痹病,筋骨痿软。见《中国药典2015年》(一部)第66页。
22、透骨草:辛,温。归肝、肾经。祛风祛湿,散瘀消肿。用于风湿痹痛,筋骨挛缩,腰部扭伤瘫痪。注意:孕妇忌用。湖南省中药饮片炮制规范(2010年版)第369页。
23、白薇:苦、咸,寒。归胃、肝、肾经。清热凉血。见《中国药典2015年》(一部)第111页。
24、辽细辛:辛,温。归心、肺、肾经。解表散寒,祛风止痛,通窍。用于头痛,风湿痹痛。见《中国药典2015年》(一部)第230页。
25、乳香:辛、苦,温。归心、肝、脾经。活血定痛,消肿。用于胸痹心痛,胃脘疼痛,风湿痹痛,筋脉拘挛,跌打损。注意:孕妇及胃弱者慎用。见《中国药典2015年》(一部)第223页。
26、元胡:辛、苦,温。归肝、脾经。活血,行气,止痛。用于跌扑肿痛。见《中国药典2015年》(一部)第140页。
27、没药:辛、苦,平。归心、肝、脾经。散瘀定痛,消肿。用于风湿痹痛,跌打损伤。注意:孕妇及胃弱者慎用,见《中国药典2015年》(一部)第189页。
28、杜仲:甘,温。归肝、肾经。补肝肾,强筋骨。用于肝肾不足,腰膝酸痛,筋骨无力,头晕目眩。见《中国药典2015年》(一部)第165页。
29、桑枝:微苦,平。归肝经。祛风湿,利关节。用于风湿痹病,肩臂、关节酸痛麻木。见《中国药典2015年》(一部)第299页。
30、羌活:辛、苦,温。归膀胱、肾经。解表散寒,祛风除湿,止痛。用于头痛项强,风湿痹痛,肩背酸痛。见《中国药典2015年》(一部)第183页。
31、三分三:苦、辛,温;有大毒。归胃、大肠、胃经。解痉止痛。用于震颤麻痹、风湿痹痛。注意:本品有大毒,慎用,青光眼患者忌服。云南省中药饮片标准2005年版第二册第9页。
32、无患子:苦、辛、微寒。归肺、脾经。清热利湿。广东省中药材标准(第二册)2011版第60页。
33、牛膝:苦、甘、酸,平。归肝、肾经。逐瘀通经,补肝肾,强筋骨。用于腰膝酸痛,筋骨无力,头痛,眩晕。注意:孕妇慎用。见《中国药典2015年》(一部)第73页。
34、三七: 散瘀止血,消肿定痛。用于跌扑肿痛。注意:孕妇慎用。见《中国药典2015年》(一部)第12页。
35、干姜:辛,热。归脾、胃、肾、心、肺经。温中散寒,回阳通脉。用于脘腹冷痛肢冷脉微。见《中国药典2015年》(一部)第14页。
36、赤芍:苦,微寒。归肝经。清热凉血,散瘀止痛。用于跌扑损伤。见《中国药典2015年》(一部)第159页。
37、追地风:又名地枫皮,辛、苦,寒。归肾、膀胱经。功能:祛风除湿,行气止痛. 主治: 用于风湿痹痛,腰肌劳损。 毒性: 微毒。见于《广西植物志》
38、樟脑:通窍,止痛,辟秽;跌打损伤。见《中国药典2015年》(二部)第1513页。
实施例2:
本发明黑膏药临床应用的典型病例统计表(20例患者):
病症:颈椎腰腿痛(18例)
治愈时间:一个月内(6例),二个月内(6例),三个月内(5例),四个月内(1例),五个月内(0例),六个月内(0例),七个月内(0例);
病症:中风后遗症(2例)
治愈时间:一个月内(0例),二个月内(0例),三个月内(0例),四个月内(0例),五个月内(0例),六个月内(0例),七个月内(2例)。
以上所述仅为本发明的较佳实施例,并非对本发明做任何形式上的限制,凡在本发明的精神和原则之内,依据本发明的技术实质对以上实施例所做的任何简单修改、等同变化与修饰,均仍属于本发明的保护范围之内。
虽然上面结合本发明的优选实施例对本发明的配方及制备流程进行了详细的描述,本领域技术人员应该理解,上述实施例仅仅是对本发明的示意性实现方式的解释,并非对本发明包含范围的限定,实施例中的细节并不构成对本发明范围的限制,在不背离本发明的精神和范围的情况下,任何基于本发明技术方案的等效变换、简单替换等显而易见的改变,均落在本发明保护范围之内。

Claims (2)

1.一种治疗颈椎腰腿痛及中风后遗症的外用黑膏药,其特征在于:它由A、B、C三组制方组成,A组药由B组药和C组药组成,A、B、C三组药既可以合成制膏,还可以分开制膏;
其中A组由38味药组成,其组分及质量配比为: 荆芥15~25,防风1~18,千年健15~25,当归5~15,鸡血藤4~12,肉桂4~12,苍耳子3~12,木瓜6~15,透骨草20~40,追地风3~12,元胡1~5,桑枝6~15,海风藤20~40,石南藤20~40,羌活3~12,独活3~9,红花3~12,赤芍3~9,桃仁3~9,川芎10~22,白微1~6,去油的乳香2~10,去油的没药2~10,牛膝1~9,丁香2~10,冰片10~30,三分三0.1~5,生马钱子6~15,生川乌1~6,生草乌1~6,生南星1~6,五加皮1~6,细辛0.3~2.5,干姜1~6,杜仲1~6,三七0.2~4,无患子0.2~4,樟脑15~35,单位为份;
B组由25味药材组成,其组分及质量配比为: 荆芥15~25,防风1~18,千年健15~25,当归5~15,鸡血藤4~12,肉桂4~12,苍耳子3~12,木瓜6~15,透骨草3~10,追地风3~12,元胡1~5,桑枝6~15,海风藤20~40,石南藤20~40,羌活3~12,独活3~9,红花3~12,赤芍3~9,桃仁3~9,川芎10~22,白微1~6,去油的乳香2~10,去油的没药2~10,牛膝1~9,丁香2~10,单位为份;
C组由13味药材组成,其组分及质量配比为:冰片10~30,三分三0.1~5,生马钱子6~15,生川乌1~6,生草乌1~6,生南星1~6,五加皮1~6,细辛0.3~2.5,干姜1~6,杜仲1~6,三七0.2~4,无患子0.2~4,樟脑15~35,单位为份。
2.根据权利要求1所述的一种治疗颈椎腰腿痛及中风后遗症的外用黑膏药,其特征在于:其制备方法为:
①原材料预处理:取配方的38味药材分别洗净,用热风烘干,所有药磨成60目粉末;
②药料的提取:取荆芥,防风,千年健,当归,鸡血藤,肉桂,苍耳子,木瓜,透骨草,追地风,元胡,桑枝,海风藤,石南藤,羌活,独活,红花,赤芍,桃仁,川芎,白微,去油的乳香,去油的没药,牛膝,丁香放入8000~33000ml麻油或豆油中泡7~9天后置锅内,加热并不断搅拌,用文火炸枯使诸药成炭直至药料炸至表面深褐色内部焦黄为度,此时温度可达220度,炸好后可用铁丝筛捞去药渣,去渣后的油为药油;
③炼油:取上述纯药油继续熬炼,待药油温度上升到320度后改用中火;炼油的火候:一是看温度计,达到规定温度;二是看油烟,开始为浅青色,渐为黑而浓,进而为白色浓烟,无风时白烟直上;三是看油花:沸腾开始时,油花多在锅壁周边附近,当油花向锅中央聚集时为度;四是看滴水成珠:取少许药油滴于水中,不散开成珠状为度;
④下丹:药油炼成后,离火下丹,一般500克油可加200克左右黄丹,黄丹在下前先干燥并过100目筛,少量加黄丹,用竹筷边加边搅动,一定要向同方向搅拌;搅成粘稠的膏体,膏药不粘手,拉丝不断为好,过硬则老,过粘则嫩;搅拌均匀后立即倒入冷水中浸泡十五天,每天换水二次去火毒;
⑤摊膏药:取下丹后的油膏稍加温至100度左右兑入冰片,生马钱子,生川乌,生草乌,生南星,五加皮,细辛,干姜,杜仲,三七,无患子,三分三,樟脑细粉拌匀,用竹筷团起,随纸布大小,以竹筷点纸布之中心作顺时针摊一周,密封保存备用。
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