CN108142950A - A kind of acer truncatum seed oil composite Nano microcapsule powder for improving brain neuroblastoma and preparation method thereof - Google Patents
A kind of acer truncatum seed oil composite Nano microcapsule powder for improving brain neuroblastoma and preparation method thereof Download PDFInfo
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- CN108142950A CN108142950A CN201711451601.4A CN201711451601A CN108142950A CN 108142950 A CN108142950 A CN 108142950A CN 201711451601 A CN201711451601 A CN 201711451601A CN 108142950 A CN108142950 A CN 108142950A
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- seed oil
- acer truncatum
- truncatum seed
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- 241000219226 Acer truncatum Species 0.000 title claims abstract description 50
- 235000015112 vegetable and seed oil Nutrition 0.000 title claims abstract description 50
- 239000003094 microcapsule Substances 0.000 title claims abstract description 37
- 239000000843 powder Substances 0.000 title claims abstract description 33
- 210000004556 brain Anatomy 0.000 title claims abstract description 32
- 239000002131 composite material Substances 0.000 title claims abstract description 32
- 206010029260 Neuroblastoma Diseases 0.000 title claims abstract description 29
- 238000002360 preparation method Methods 0.000 title claims abstract description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 26
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims abstract description 15
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims abstract description 8
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims abstract description 7
- 125000002252 acyl group Chemical group 0.000 claims abstract description 7
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 7
- 239000000945 filler Substances 0.000 claims abstract description 7
- 239000003381 stabilizer Substances 0.000 claims abstract description 7
- 239000003963 antioxidant agent Substances 0.000 claims abstract description 6
- 230000003078 antioxidant effect Effects 0.000 claims abstract description 6
- 239000000839 emulsion Substances 0.000 claims description 19
- 239000003921 oil Substances 0.000 claims description 16
- 235000019198 oils Nutrition 0.000 claims description 16
- 239000006210 lotion Substances 0.000 claims description 12
- 239000000203 mixture Substances 0.000 claims description 11
- 238000000034 method Methods 0.000 claims description 9
- 239000002245 particle Substances 0.000 claims description 8
- 238000001694 spray drying Methods 0.000 claims description 8
- 238000004945 emulsification Methods 0.000 claims description 7
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 6
- 235000006708 antioxidants Nutrition 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 5
- 239000008187 granular material Substances 0.000 claims description 5
- 230000006872 improvement Effects 0.000 claims description 5
- 238000010008 shearing Methods 0.000 claims description 5
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 4
- 102000004407 Lactalbumin Human genes 0.000 claims description 4
- 108090000942 Lactalbumin Proteins 0.000 claims description 4
- 229920002774 Maltodextrin Polymers 0.000 claims description 4
- 239000005913 Maltodextrin Substances 0.000 claims description 4
- 239000005018 casein Substances 0.000 claims description 4
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims description 4
- 235000021240 caseins Nutrition 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 4
- 229940035034 maltodextrin Drugs 0.000 claims description 4
- 229910052708 sodium Inorganic materials 0.000 claims description 4
- 239000011734 sodium Substances 0.000 claims description 4
- 238000005507 spraying Methods 0.000 claims description 4
- MJYQFWSXKFLTAY-OVEQLNGDSA-N (2r,3r)-2,3-bis[(4-hydroxy-3-methoxyphenyl)methyl]butane-1,4-diol;(2r,3r,4s,5s,6r)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O.C1=C(O)C(OC)=CC(C[C@@H](CO)[C@H](CO)CC=2C=C(OC)C(O)=CC=2)=C1 MJYQFWSXKFLTAY-OVEQLNGDSA-N 0.000 claims description 3
- 108010010803 Gelatin Proteins 0.000 claims description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 3
- QAQJMLQRFWZOBN-LAUBAEHRSA-N L-ascorbyl-6-palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O QAQJMLQRFWZOBN-LAUBAEHRSA-N 0.000 claims description 3
- 239000011786 L-ascorbyl-6-palmitate Substances 0.000 claims description 3
- 229920002472 Starch Polymers 0.000 claims description 3
- 241001122767 Theaceae Species 0.000 claims description 3
- 229930003427 Vitamin E Natural products 0.000 claims description 3
- 235000010489 acacia gum Nutrition 0.000 claims description 3
- 239000001785 acacia senegal l. willd gum Substances 0.000 claims description 3
- 235000010385 ascorbyl palmitate Nutrition 0.000 claims description 3
- 235000004426 flaxseed Nutrition 0.000 claims description 3
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 3
- 229920000159 gelatin Polymers 0.000 claims description 3
- 239000008273 gelatin Substances 0.000 claims description 3
- 235000019322 gelatine Nutrition 0.000 claims description 3
- 235000011852 gelatine desserts Nutrition 0.000 claims description 3
- 239000008103 glucose Substances 0.000 claims description 3
- 150000008442 polyphenolic compounds Chemical class 0.000 claims description 3
- 235000013824 polyphenols Nutrition 0.000 claims description 3
- 239000008107 starch Substances 0.000 claims description 3
- 235000019698 starch Nutrition 0.000 claims description 3
- 235000019165 vitamin E Nutrition 0.000 claims description 3
- 229940046009 vitamin E Drugs 0.000 claims description 3
- 239000011709 vitamin E Substances 0.000 claims description 3
- 238000012216 screening Methods 0.000 claims description 2
- DWNBOPVKNPVNQG-LURJTMIESA-N (2s)-4-hydroxy-2-(propylamino)butanoic acid Chemical compound CCCN[C@H](C(O)=O)CCO DWNBOPVKNPVNQG-LURJTMIESA-N 0.000 claims 1
- 238000005516 engineering process Methods 0.000 abstract description 5
- 239000004519 grease Substances 0.000 abstract description 5
- 230000036541 health Effects 0.000 abstract description 4
- 239000000047 product Substances 0.000 description 7
- GWHCXVQVJPWHRF-KTKRTIGZSA-N (15Z)-tetracosenoic acid Chemical compound CCCCCCCC\C=C/CCCCCCCCCCCCCC(O)=O GWHCXVQVJPWHRF-KTKRTIGZSA-N 0.000 description 5
- XJXROGWVRIJYMO-SJDLZYGOSA-N Nervonic acid Natural products O=C(O)[C@@H](/C=C/CCCCCCCC)CCCCCCCCCCCC XJXROGWVRIJYMO-SJDLZYGOSA-N 0.000 description 5
- GWHCXVQVJPWHRF-UHFFFAOYSA-N cis-tetracosenoic acid Natural products CCCCCCCCC=CCCCCCCCCCCCCCC(O)=O GWHCXVQVJPWHRF-UHFFFAOYSA-N 0.000 description 5
- 239000011162 core material Substances 0.000 description 3
- TZCPCKNHXULUIY-RGULYWFUSA-N 1,2-distearoyl-sn-glycero-3-phosphoserine Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCCCCCCCCCCCC TZCPCKNHXULUIY-RGULYWFUSA-N 0.000 description 2
- ZWZWYGMENQVNFU-UHFFFAOYSA-N Glycerophosphorylserin Natural products OC(=O)C(N)COP(O)(=O)OCC(O)CO ZWZWYGMENQVNFU-UHFFFAOYSA-N 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- 208000024827 Alzheimer disease Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 1
- 241000549556 Nanos Species 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 206010033799 Paralysis Diseases 0.000 description 1
- 206010039966 Senile dementia Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000003920 cognitive function Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000008157 edible vegetable oil Substances 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 235000004626 essential fatty acids Nutrition 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000000446 fuel Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 150000002617 leukotrienes Chemical class 0.000 description 1
- 235000020778 linoleic acid Nutrition 0.000 description 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000006386 memory function Effects 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000007433 nerve pathway Effects 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 150000008106 phosphatidylserines Chemical class 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000007634 remodeling Methods 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 239000002351 wastewater Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The present invention relates to health product technology fields more particularly to a kind of acer truncatum seed oil composite Nano microcapsule powder for improving brain neuroblastoma and preparation method thereof.The acer truncatum seed oil composite Nano microcapsule powder for improving brain neuroblastoma is made of the component of following parts by weight：65~80 parts of 38~45 parts of acer truncatum seed oil, 6~8 parts of phosphoric acid acyl serine, 0.002~0.02 part of antioxidant, 48~54 parts of filler, 6~8 parts of emulsifier, 0~0.1 part of stabilizer and water.The acer truncatum seed oil composite microcapsule powder product that the present invention obtains is Instant product, and good fluidity, rehydration stability is good, and the grease embedding rate of micro-capsule is high, and embeddability properties are good, features good taste, and absorptivity is high.
Description
Technical field
The present invention relates to health product technology field more particularly to a kind of acer truncatum seed oil composite Nanos for improving brain neuroblastoma
Microcapsule powder and preparation method thereof.
Background technology
Acer truncatum seed oil belongs to semi-drying oil, and new resource food was used as by health ministry approval in 2011.In fat
In acid composition, acer truncatum seed oil unsaturated fatty acid content is up to 92%, and wherein oleic acid and linoleic content is up to
79.28%.Linoleic acid is essential fatty acid, has the function of reducing blood lipid, blood pressure lowering, softening blood vessel, promotes microcirculation, can
Prevention or the incidence for reducing cardiovascular disease.Simultaneously rich in nervonic acid in acer truncatum seed oil, up to 5% or so.Nervonic acid is the world
It is that scientist generally acknowledges, unique to repair dredging injured brain nerve pathway nerve fibre and promote the regenerated economic benefits and social benefits god of nerve cell
Strange substance, the shortage of nervonic acid can cause cerebral apoplexy sequela, senile dementia, brain paralysis, encephalatrophy, failure of memory, insomnia strong
The diseases such as forget.In addition, acer truncatum seed oil can improve person in middle and old age's body immune system also rich in VE, VA etc..And human body itself is difficult
Generate nervonic acid, it is necessary to supplement by external world's intake.Therefore, acer truncatum seed oil is the high-quality original for preparing person in middle and old age's nutrient and healthcare products
Material.
Phosphatidylserine (PS) has important role to the improvement of brain cognitive function and memory function.It is edible daily
300~500mg phosphatidylserines can be obviously improved memory after one month.At present, acer truncatum seed oil is main in the market
It is eaten as edible oil, capsule, tablet, bioavailability is relatively low, fails to give full play to the value of its nutrition and health care.
Invention content
The present invention is low in order to overcome the problems, such as traditional acer truncatum seed oil bioavailability, provides a kind of improvement brain neuroblastoma
Acer truncatum seed oil composite Nano microcapsule powder.
The present invention also provides a kind of preparation methods for the acer truncatum seed oil composite Nano microcapsule powder for improving brain neuroblastoma.
To achieve these goals, the present invention uses following technical scheme：
A kind of acer truncatum seed oil composite Nano microcapsule powder for improving brain neuroblastoma, the acer truncatum seed oil for improving brain neuroblastoma are answered
Nano-microcapsule powder is closed to be made of the component of following parts by weight：38~45 parts of acer truncatum seed oil, 6~8 parts of phosphoric acid acyl serine, antioxygen
65~80 parts of 0.002~0.02 part of agent, 48~54 parts of filler, 6~8 parts of emulsifier, 0~0.1 part of stabilizer and water.
Preferably, the filler is maltodextrin or glucose.
Preferably, the emulsifier is one or more in casein sodium, converted starch and lactalbumin.
Preferably, the stabilizer is one or more in gelatin, Arabic gum and flaxseed gum.
Preferably, the antioxidant is selected from phosphatide, and vitamin E, one in ascorbyl palmitate and tea polyphenols
Kind is a variety of.
A kind of preparation method for the acer truncatum seed oil composite Nano microcapsule powder for improving brain neuroblastoma, includes the following steps：
(1) prepared by water phase：According to said ratio, filler, emulsifier and stabilizer are sequentially added in water, keep temperature W1 simultaneously
The T1 times are stirred to dissolving, water phase is made；W1 ＞ 0, T1 ＞ 0；
(2) prepared by oil phase：By acer truncatum seed oil, phosphoric acid acyl serine is miscible under temperature W2 with antioxidant, and oil phase is made；W2
＞ 0；
(3) it just emulsifies：Oil phase is slowly added to obtain mixture in water phase, using cutter to mixture high speed shearing emulsification shape
Into O/W type lotions；
(4) homogeneous：The homogeneous of T2 times is carried out to lotion using secondary pressure homogenizer, emulsion is obtained, is slowly stirred emulsification
The liquid T3 times；T2 ＞ 0, T3 ＞ 0；
(5) it granulates：By emulsion obtained above, using the method for spray drying, it is W3 to keep emulsion temperature, will be emulsified
Particle made from after liquid is spray-dried, screening, cooling, obtains the acer truncatum seed oil composite Nano micro-capsule for improving brain neuroblastoma
Powder；W3 ＞ 0.
Preferably, in step (1), 50 DEG C≤W1≤70 DEG C, 0.3h≤T1≤0.5h.
Preferably, in step (2), 50 DEG C≤W2≤70 DEG C.
Preferably, in step (4), 0.4h≤T2≤0.6h, 0.4h≤T3≤0.6h.
Preferably, in step (5), 60 DEG C≤W3≤68 DEG C, the inlet air temperature of spray drying is 150~170 DEG C, spraying
Dry leaving air temp is 70~80 DEG C.
Acer truncatum seed oil composite microcapsule powder the present invention provides a kind of optimization and preparation method thereof, using the technology of the present invention
The final products that scheme obtains display surface under environmental scanning electronic microscope is spherical in shape, and particle size range obtains between 40~110 μm
Acer truncatum seed oil composite microcapsule powder product for Instant product, good fluidity, rehydration stability is good, the grease embedding rate of micro-capsule
Height, embeddability properties are good, features good taste, and absorptivity is high；Meanwhile preparation process of the invention is simple, convenient for large-scale production, micro-capsule packet
The technology of burying can effectively completely cut off contact of the acer truncatum seed oil with air, protect in acer truncatum seed oil leukotrienes and nervonic acid etc. effectively into
The bioactivity divided, production process is generated without waste residue, waste water, environmentally protective.
Specific embodiment
Below by specific embodiment, the technical solutions of the present invention will be further described.
In the present invention, if not refering in particular to, all devices and raw material is commercially available or the industry is common are following
Method in embodiment is this field conventional method unless otherwise instructed.
Embodiment 1
(1) prepared by water phase：Maltodextrin 480g, casein sodium 30g, converted starch 30g and Arabic gum 1g are sequentially added
In 650g water, keep temperature 50 C and stir 0.3h to dissolving, water phase is made；
(2) prepared by oil phase：Acer truncatum seed oil 380g, phosphoric acid acyl serine 60g and vitamin E 0.02g are mixed under temperature 50 C
It is molten, oil phase is made；
(3) it just emulsifies：Oil phase is slowly added to obtain mixture in water phase, using cutter to mixture high speed shearing emulsification
0.25h forms O/W type lotions, and cutter rotating speed is 12000r/min；
(4) homogeneous：The homogeneous of 0.6h is carried out to lotion using secondary pressure homogenizer, emulsion is obtained, is slowly stirred emulsion
0.4h；
(5) it granulates：Using the method for spray drying, it is 60 DEG C to keep emulsion temperature, by the spray-dried rear system of emulsion
Particle is obtained, the inlet air temperature of spray drying is 170 DEG C, 80 DEG C of leaving air temp, particle sieve made from after emulsion is spray-dried
Point, cooling obtains the acer truncatum seed oil composite Nano microcapsule powder for improving brain neuroblastoma.
Embodiment 2
(1) prepared by water phase：Maltodextrin 540g, lactalbumin 80g are sequentially added in 700g water, keep temperature 60 C and stirred
To dissolving, water phase is made in the 0.4h times；
(2) prepared by oil phase：By acer truncatum seed oil 450g, phosphoric acid acyl serine 80g, phosphatidase 0 .1g and ascorbyl palmitate
0.1g is miscible at 60 DEG C, and oil phase is made；
(3) it just emulsifies：Oil phase is slowly added to obtain mixture in water phase, using cutter to mixture high speed shearing emulsification
0.25h forms O/W type lotions, and cutter rotating speed is 20000r/min；
(4) homogeneous：The homogeneous of 0.4h is carried out to lotion using secondary pressure homogenizer, emulsion is obtained, is slowly stirred emulsion
0.5h；
(5) it granulates：Lotion obtained above is dried in the spray drying tower, it is 65 DEG C to keep emulsion temperature, and spraying is dry
Dry inlet air temperature is 150 DEG C, 70 DEG C of leaving air temp, and the spray-dried rear obtained particle of emulsion sieves, cooling is made
The acer truncatum seed oil composite Nano microcapsule powder of brain neuroblastoma must be improved.
Embodiment 3
(1) prepared by water phase：By glucose 500g, casein sodium 30g, lactalbumin 37g, gelatin 0.5g and flaxseed gum 0.2g
It sequentially adds in 800g water, keep temperature 70 C and stirs 0.5h to dissolving, water phase is made；
(2) prepared by oil phase：By acer truncatum seed oil 400g, phosphoric acid acyl serine 63g, tea polyphenols 0.15g is miscible at 70 DEG C, is made
Oil phase；
(3) it just emulsifies：Oil phase is slowly added to obtain mixture in water phase, using cutter to mixture high speed shearing emulsification
0.25h forms O/W type lotions, and cutter rotating speed is 18000r/min；
(4) homogeneous：The homogeneous of 0.5h is carried out to lotion using secondary pressure homogenizer, emulsion is obtained, is slowly stirred emulsion
0.6h；
(5) it granulates：Lotion obtained above is dried in the spray drying tower, it is 68 DEG C to keep emulsion temperature, and spraying is dry
Dry inlet air temperature is 160 DEG C, 75 DEG C of leaving air temp, and the spray-dried rear obtained particle of emulsion sieves, cooling is made
The acer truncatum seed oil composite Nano microcapsule powder of brain neuroblastoma must be improved.
The acer truncatum seed oil composite Nano microcapsule powder performance indicator for improving brain neuroblastoma made from embodiment 1-3 is examined
It surveys, the results are shown in Table 1：
1. testing result of table
| Performance indicator | Embodiment 1 | Embodiment 2 | Embodiment 3 |
| Grain size/μm | 35~70 | 45~100 | 40~70 |
| Fuel load/% | 37.75 | 37.43 | 39.82 |
| Water content/% | 3.0 | 3.2 | 3.1 |
| Grease embedding rate % | 99.35 | 98.5 | 99.55 |
| Stability | Rehydration stability is good, core material is stablized | Rehydration stability is good, core material is stablized | Rehydration stability is good, core material is stablized |
In table：Water content is the mass percent of water in the acer truncatum seed oil composite Nano microcapsule powder for improve brain neuroblastoma；
Grease embedding rate is mass percent.
As can be seen from Table 1, the acer truncatum seed oil composite Nano microcapsule powder particle size range of improvement brain neuroblastoma of the invention
Between 40~110 μm, obtained acer truncatum seed oil composite microcapsule powder product is Instant product, good fluidity, and rehydration is stablized
Property it is good, the grease embedding rate of micro-capsule is high, and embeddability properties are good, features good taste, and absorptivity is high.
The foregoing is merely presently preferred embodiments of the present invention, not makees limitation in any form to the present invention, is not surpassing
There are other variants and remodeling under the premise of going out the technical solution recorded in claim.
Claims (10)
- A kind of 1. acer truncatum seed oil composite Nano microcapsule powder for improving brain neuroblastoma, which is characterized in that the improvement brain neuroblastoma Acer truncatum seed oil composite Nano microcapsule powder be made of the component of following parts by weight：38~45 parts of acer truncatum seed oil, phosphoric acid acyl silk 6~8 parts of propylhomoserin, 0.002~0.02 part of antioxidant, 48~54 parts of filler, 6~8 parts of emulsifier, 0~0.1 part of stabilizer and 65~80 parts of water.
- 2. a kind of acer truncatum seed oil composite Nano microcapsule powder for improving brain neuroblastoma according to claim 1, feature exist In the filler is maltodextrin or glucose.
- 3. a kind of acer truncatum seed oil composite Nano microcapsule powder for improving brain neuroblastoma according to claim 1, feature exist In the emulsifier is one or more in casein sodium, converted starch and lactalbumin.
- 4. a kind of acer truncatum seed oil composite Nano microcapsule powder for improving brain neuroblastoma according to claim 1, feature exist In the stabilizer is one or more in gelatin, Arabic gum and flaxseed gum.
- 5. a kind of acer truncatum seed oil composite Nano microcapsule powder for improving brain neuroblastoma according to claim 1, feature exist Phosphatide is selected from, the antioxidant, and vitamin E is one or more in ascorbyl palmitate and tea polyphenols.
- 6. a kind of preparation of the acer truncatum seed oil composite Nano microcapsule powder of improvement brain neuroblastoma as described in claim 1-5 is any Method, which is characterized in that include the following steps：(1) prepared by water phase：According to said ratio, filler, emulsifier and stabilizer are sequentially added in water, keep temperature W1 simultaneously The T1 times are stirred to dissolving, water phase is made；W1 ＞ 0, T1 ＞ 0；(2) prepared by oil phase：By acer truncatum seed oil, phosphoric acid acyl serine is miscible under temperature W2 with antioxidant, and oil phase is made；W2 ＞ 0；(3) it just emulsifies：Oil phase is slowly added to obtain mixture in water phase, using cutter to mixture high speed shearing emulsification shape Into O/W type lotions, the cutter rotating speed is 12000~20000r/min；(4) homogeneous：The homogeneous of T2 times is carried out to lotion using secondary pressure homogenizer, emulsion is obtained, is slowly stirred emulsification The liquid T3 times；T2 ＞ 0, T3 ＞ 0；(5) it granulates：By emulsion obtained above, using the method for spray drying, it is W3 to keep emulsion temperature, will be emulsified Particle made from after liquid is spray-dried, screening, cooling, obtains the acer truncatum seed oil composite Nano micro-capsule for improving brain neuroblastoma Powder；W3 ＞ 0.
- 7. a kind of preparation side of acer truncatum seed oil composite Nano microcapsule powder for improving brain neuroblastoma according to claim 6 Method, which is characterized in that in step (1), 50 DEG C≤W1≤70 DEG C, 0.3h≤T1≤0.5h.
- 8. a kind of preparation side of acer truncatum seed oil composite Nano microcapsule powder for improving brain neuroblastoma according to claim 6 Method, which is characterized in that in step (2), 50 DEG C≤W2≤70 DEG C.
- 9. a kind of preparation side of acer truncatum seed oil composite Nano microcapsule powder for improving brain neuroblastoma according to claim 6 Method, which is characterized in that in step (4), 0.4h≤T2≤0.6h, 0.4h≤T3≤0.6h.
- 10. a kind of preparation side of acer truncatum seed oil composite Nano microcapsule powder for improving brain neuroblastoma according to claim 9 Method, which is characterized in that in step (5), 60 DEG C≤W3≤68 DEG C, the inlet air temperature of spray drying is 150~170 DEG C, and spraying is dry Dry leaving air temp is 70~80 DEG C.
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| CN113974163A (en) * | 2020-07-27 | 2022-01-28 | 山东荆卫生物科技有限公司 | Microcapsule powder containing acer truncatum oil and ketone compounds as well as preparation method and application of microcapsule powder |
| CN115005353A (en) * | 2022-06-17 | 2022-09-06 | 安徽易健和医疗科技有限公司 | DHA algae oil composite protein solid beverage and preparation method thereof |
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