CN108126173A - A kind of composition of medicine for treating fungal dermatopathy and preparation method thereof - Google Patents
A kind of composition of medicine for treating fungal dermatopathy and preparation method thereof Download PDFInfo
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- CN108126173A CN108126173A CN201711491092.8A CN201711491092A CN108126173A CN 108126173 A CN108126173 A CN 108126173A CN 201711491092 A CN201711491092 A CN 201711491092A CN 108126173 A CN108126173 A CN 108126173A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/32—Manganese; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
Abstract
The present invention relates to a kind of composition of medicine for treating fungal dermatopathy, it includes soaking agent and applies cream；Soaking agent weight ratio part has 13 parts of Sulfur, 0.5 1 parts of potassium permanganate, 12 parts of salicylic acid, 35 parts of ginger, 35 parts of garlic, 13 parts of salt；Painting cream weight ratio part, which is made, 12 parts of 5 fluorouracil, 9 11 parts of vaseline.Soaking agent, which is pressed, matches 35 45 DEG C of warm water 1L per 100g, immersion agent solution is put into clean towel to be impregnated with, it applies a hot compress to the affected part, play softening illing skin cutin, sterilizing, ginger can distend the blood vessels the pore with promoting opening, garlic is natural plant broad-spectrum antibiotic, after completing aforesaid operations, the painting cream of above-mentioned making is applied in affected part；5 fluorouracils in cream are applied under local environment, since illing skin pore opens the capillary diastole with periphery, 5 fluorouracils are locally being easier to enter deep tissues, so as to kill fungi, and will not generate side effect, and uneasy to recur from profound.
Description
Technical field
The invention belongs to pharmaceutical technology field, more particularly, to the drug for the treatment of fungal dermatopathy.
Background technology
Fungal infection can be divided into two class of the shallow fungal infection of table and deep fungal infection, and the shallow infection of table is to invade skin by tinea bacterium
Skin, hair, caused by referring to (toe) first-class body surface, incidence is high, and harmfulness is smaller, but is brought to life, working and learning
Very big puzzlement, most skin disease particularly tickle less refined, can cause very big with symptoms such as itch, pain, bleedings
Sticky feeling and certain inferiority complex.Deep fungal infection is to invade internal organs and deep group by candida albicans and cryptococcus
Caused by knitting, incidence is low, and harmfulness is big.
Common antifungal is divided into treatment superficial fungal infection drug according to site of action undecenoic acid, salicylic acid, breast
Acid, acetic acid, griseofulvin, cannitracin, clotrimazole, Miconazole, econazole, bifonazole, ketoconazole etc., due to fungoid skin
Skin disease drug resistance is strong, individually with salicylic acid, salicylic acid or is applied in combination, all easily recurrence.Anti- deep fungal infection drug has fluorine born of the same parents
Pyrimidine, amphotericin B, nystatin, globoroseomycin, methylpartricin (mepartricin, methylpartricin sodium laurylsulfate), Fluconazole (Fluconazole, wheat Buddhist nun
Fragrant, Yi Likang), Itraconazole (Sporanox) etc., such as directly rub fungal dermatopathy with the anti-deep drug of Flucytosine
Affected part, effect is very limited, such as the injection anti-deep drug of Flucytosine, toxic side effect cause organ bad
It influences.
Invention content
The purpose of the present invention is to provide a kind of therapeutic effect is good, high efficiency, recurrence rate is low has no toxic and side effect to human body
Treatment fungal dermatopathy drug.
The object of the present invention is achieved like this, is made of two parts, wherein having soaking agent and applying cream, soaking agent is by sulphur
Huang, potassium permanganate, salicylic acid, ginger, garlic, salt are according to weight ratio compatibility, by every 100g with 35-45 DEG C of warm water 1L, with dry
Net towel is put into soaking agent and is impregnated with, and applies a hot compress to the affected part 3-5 minutes, impregnates towel again, gently wipe affected part, scurf is cleaned dry
Only；Soaking agent plays softening affected part crust, and sterilizing, potassium permanganate, Sulfur are killed antifungal effect under acidic environment and significantly carried
Height, for salicylic acid in the case of 35-45 DEG C of temperature, cutin-softening crust effect is very good, and has stronger bactericidal properties, simultaneously
Acidic environment is provided for solution again, it is more preferable compared with the effect of acetic acid；Ginger can distend the blood vessels, blood circulation accelerate, promote with
Pore open, garlic is natural plant broad-spectrum antibiotic, and allicin antibacterial effect therein is very good, aforesaid right will
The weight ratio range class and the proportioning with water for seeking 1 li of salt, salt has the function of sterilization, while plays maintenance local organization again
Osmotic pressure effect；After completing aforesaid operations, the painting cream of above-mentioned making is applied in affected part, once a day, 5 days courses for the treatment of；Apply cream
In 5 FU 5 fluorouracil under local environment, due to illing skin pore open and periphery capillary diastole, 5- fluorine urine it is phonetic
Pyridine is locally being easier to enter deep tissues, so as to kill fungi from profound level, and will not generate side effect, and completely cut off affected part again
Skin and the external world are in direct contact, therefore, it is of the invention the effect of clearly, it is and uneasy to recur.Its invention is as follows：
A kind of composition of medicine for treating fungal dermatopathy, it includes soaking agent and applies cream, and the raw material weight of soaking agent is made
Amount has 1-3 parts of Sulfur, 0.5-1 parts of potassium permanganate, 1-2 parts of salicylic acid, 3-5 parts of ginger, 3-5 parts of garlic, 1-3 parts of salt than part；
The raw material weight for applying cream is made has 1-2 parts of 5 FU 5 fluorouracil, 9-11 parts of vaseline than part；
As a further improvement of the above technical scheme：
It is made of following raw material medicaments：Soaking agent：It is 3 parts of Sulfur, 1 part of potassium permanganate, 1 part of salicylic acid, 5 parts of ginger, big
5 parts of garlic, 3 parts of salt；Apply cream：2 parts of 5 FU 5 fluorouracil, 9 parts of vaseline.
It is made of following raw material medicaments：Soaking agent：1 part of Sulfur, 0.5 part of potassium permanganate, 1 part of salicylic acid, 3 parts of ginger,
3 parts of garlic, 2 parts of salt；Apply cream：1 part of 5 FU 5 fluorouracil, 9 parts of vaseline.
It is made of following raw material medicaments：Soaking agent：It is 1 part of Sulfur, 1 part of potassium permanganate, 1 part of salicylic acid, 5 parts of ginger, big
3 parts of garlic, 2 parts of salt；Apply cream：2 parts of 5 FU 5 fluorouracil, 11 parts of vaseline.
A kind of composition of medicine processing method of the treatment fungal dermatopathy, includes the following steps：
The preparation method of soaking agent：
The first step：Pulverizer first will be blended in by ginger, garlic and be ground into smalls；
Second step：Sulfur, potassium permanganate, salicylic acid, ginger garlic are mixed into smalls, salt again, are placed in blender stirring
Mixing 10 minutes -30 minutes；
Third walks：Examine the uniformity, 100 grams by weight either 200 grams or 300 grams or 500 grams of units are used
Glass bottle packaging；
Apply the preparation method of cream：
The first step：Vaseline, 5 FU 5 fluorouracil mixing are placed in blender and be stirred 10 minutes -30 minutes；
Second step：Examine the uniformity, 10 grams by weight either 20 grams or 30 grams of unit vials or plastics
Bottle packaging.
Advantageous effect
The present invention is made of two parts, wherein having soaking agent and applying cream, soaking agent is by Sulfur, potassium permanganate, salicylic acid, life
Ginger, garlic, salt, by every 100g with 35-45 DEG C of warm water 1L, are stirred, are put with clean towel according to weight ratio compatibility
Enter soaking agent to be impregnated with, apply a hot compress to the affected part 3-5 minutes, impregnate towel again, gently wipe affected part, scurf is cleaned up；Soaking agent
It plays softening illing skin cutin and crust, sterilizing, potassium permanganate, Sulfur is killed antifungal effect under acidic environment and significantly carried
Height, for salicylic acid in the case of 35-45 DEG C of temperature, cutin-softening crust effect is very good, and has stronger bactericidal properties, simultaneously
Acidic environment is provided for solution again, it is more preferable compared with the effect of acetic acid；Ginger can distend the blood vessels, blood circulation accelerate, promote with
Pore open, garlic is natural plant broad-spectrum antibiotic, and allicin antibacterial effect therein is very good, aforesaid right will
The weight ratio range class and the proportioning with water for seeking 1 li of salt, salt has the function of sterilization, while plays maintenance local organization again
Osmotic pressure effect；After completing aforesaid operations, the painting cream of above-mentioned making is applied in affected part, once a day, 5 days courses for the treatment of；It applies
5 FU 5 fluorouracil in cream is under local environment, since illing skin pore opens the capillary diastole with periphery, 5- fluorine urine
Pyrimidine is locally being easier to enter deep tissues, so as to kill fungi from profound level, and will not generate side effect, and isolation is suffered from again
Place's skin and the external world are in direct contact, therefore, it is of the invention the effect of clearly, it is and uneasy to recur.Common health azole emulsifiable paste pair
Profound biocidal efficacies are general, easily recur, if injection 5 FU 5 fluorouracil, and deleterious effect can be caused to human organ, because
This, the present invention had not only solved the problems, such as that fungal dermatopathy easily recurred, but also will not cause side effect to human body.
Specific embodiment
With reference to embodiment, the present invention is further illustrated, and following embodiments are merely to illustrate of the invention and right
There is no limit by the present invention.
Embodiment 1, a kind of composition of medicine for treating fungal dermatopathy, weight ratio are；Soaking agent：3 parts of Sulfur, Gao Meng
Sour 1 part of potassium, 1 part of salicylic acid, 5 parts of ginger, 5 parts of garlic, 3 parts of salt；Apply cream：2 parts of 5 FU 5 fluorouracil, 9 parts of vaseline.
Embodiment 2, a kind of composition of medicine for treating fungal dermatopathy, weight ratio are；Soaking agent：1 part of Sulfur, Gao Meng
Sour 0.5 part of potassium, 1 part of salicylic acid, 3 parts of ginger, 3 parts of garlic, 2 parts of salt；Apply cream：1 part of 5 FU 5 fluorouracil, 9 parts of vaseline.
Embodiment 3, a kind of composition of medicine for treating fungal dermatopathy, weight ratio are；Soaking agent：1 part of Sulfur, Gao Meng
Sour 1 part of potassium, 1 part of salicylic acid, 5 parts of ginger, 3 parts of garlic, 2 parts of salt；Apply cream：2 parts of 5 FU 5 fluorouracil, 11 parts of vaseline.
Model case 1：It is remaining certain, female, 19 years old, student suffered from tinea pedis half a year, toe space itch when incipient, rear peeling,
Do not take notice of very much, at will bought a little medicines of point and smeared, behind it is increasingly severe, decortication, itch, fester, stink still very greatly, serious shadow
Ring work and life.After treating half a year repeatedly, very itch unbearably；Afterwards with present invention treatment, it is in foot due to suffering from, is converted with soaking agent
35-45 DEG C of warm water impregnates, and coats the painting cream of the present invention, and itch is eliminated after 2 days, and after 1 course for the treatment of, healing of festering peels etc. other
Tinea pedis symptom is all eliminated, and grows the new skin of health, and no recurrence is paid a return visit in 2 course for the treatment of recoveries from illness.
Model case 2：Chen, 42 years old, man, the middle age put on weight, and build is fat, suffers from jock itch, not how note that having when just starting
Small red dot, for edge clear, the erythema slightly swelled, after expand gradually, play blister, brown switched to by red gradually, through common
Hand itching, as a result the center of disease damage heal automatically gradually, develop to surrounding, and cause many places crust, the edge inflammation ratio of erythema
It is more apparent, can there are fash, blister, crust or even erosion above, form annular.Afterwards with present invention treatment, pruritis after 3 days
Substantially reduced, blister water disappears after 1 course for the treatment of, and crust is fallen, and 2 course for the treatment of recoveries from illness are paid a return visit in 2 years without recurrence.
Model case 3：Multitude XX, man, 50 years old.Suffer from tinea versicolor 4 years, have round dotted macula from the beginning of abdomen, how not notice,
Gradually increase afterwards, the drug therapy of ointments is bought in pharmacy, without too big effect, after it is more serious, cause it is adjacent damage into
Big sheet, surrounding have new fash to occur again, and fash surface is in the past few years controlled repeatedly with a small amount of brown furfuraceous desquamation easily removed
Treat and never fully recover, annual summer especially severe, after body multiple location is caused to infect, rear present invention treatment, after 1 course for the treatment of
Schultz-Charlton, decrustation are fully recovered after 2 courses for the treatment of, and follow-up 3 years is without recurrence.
The pharmacological action of drug of the present invention is as follows：
Potassium permanganate：Strong oxidizer has strong oxidizing property, has bactericidal effect, bactericidal effect is stronger under acidic environment.
Salicylic acid：With the functions such as bad smell of perspiration, relieving itching and eliminating swelling, analgesic antiphlogistic in addition to antisepsis and sterilization effect, are also dispelled, soften
Cutin, while acidic environment can be provided again.
Sulfur：Effect is that external application energy desinsection is antipruritic, available for generating sulphur after mange, eczema, pruitus, with skin contact
Change hydrogen and pentathionic acid, sarcoptic mite, killing fungus can be killed, moreover it is possible to lose hair or feathers.
Ginger：Ginger can distend the blood vessels, blood circulation accelerate, promote with pore open.
Garlic：Garlic is natural plant broad-spectrum antibiotic, and allicin therein is very good to anti-bacterial effect.
Salt：Food stops Shangwan, trusted subordinate's abdominal distension, phlegm addiction in brain, constipation and anuresis, and gingiva bleeding gingival hemorrhage is had sore throat, toothache, mesh screen, sore,
Insect bite.
5 FU 5 fluorouracil：It is worked with antimetabolite, is converted into effective fluorodeoxyuridine acid in the cell
Afterwards, by the way that deoxyribouridine acid is blocked to be converted into thymidylic acid by intracellular thymidylate synthetase, and the synthesis of DNA is interfered.Fluorine
Uracil equally can be with the synthesis of RNA interfering.
Vaseline：Great chemically inert hydrocarbon, not hydrophilic, smearing can keep skin wet on the skin,
The skin histology of wound location is made to keep optimum state, the repair ability of skin itself is accelerated, stops thin in air
Bacterium and skin contact, so as to reduce the possibility of infection.
The drug processing method of the present invention, includes the following steps：
The preparation method of soaking agent：
The first step：Pulverizer first will be blended in by ginger, garlic and be ground into smalls.
Second step：Sulfur, potassium permanganate, salicylic acid, ginger garlic are mixed into smalls, salt again, are placed in blender stirring
Mixing 10 minutes -30 minutes.
Third walks：Examine the uniformity, 100 grams by weight either 200 grams or 300 grams or 500 grams of units are used
Glass bottle packaging.
Apply the preparation method of cream：
The first step：Vaseline, 5 FU 5 fluorouracil mixing are placed in blender and be stirred 10 minutes -30 minutes.
Second step：Examine the uniformity, 10 grams by weight either 20 grams or 30 grams of unit vials or plastics
Bottle packaging.
The administrated method of the present invention：Soaking agent presses the water 1L of 35-45 DEG C of the proportioning per 100g, stirs into solution, can impregnate trouble
Place also can hot compress 3-5 minute, painting cream is then applied to affected part again.
Points for attention：Forbidden eye, mouth, entering eyes accidentally needs a large amount of clear water to rinse, and see a doctor in time.
Clinical effectiveness for the drug for showing the present invention, for treating ringworm of the body, with the common health azoles emulsifiable paste of 100 uses
With 100 cases using the drug therapy ringworm of the body of the present invention, compared.
The diagnostic criteria of ringworm of the body：Ringworm of the body is as caused by fungal infection, and erythema, fash, mound occur for fungus-caused skin
The damages such as rash, blister, there is furfur, and often annular in shape etc., it is ringworm of the body to meet above-mentioned symptom.Case is equal used by this contrast test
For the case that clinical definite is ringworm of the body.
The criterion of curative effect：Recovery from illness：Fash all subsides, no scratchiness, and fungi plate coating checking is negative；It is effective：Fash
More than 60% recession, itch are alleviated or occasionally have itch, and fungi plate coating checking is negative；Effectively：Deflorescence 30%~60%, slightly
Itch, fungi plate coating checking are positive；In vain：Deflorescence is less than 30% or does not subside or aggravate, and scratchiness is more apparent, and fungi applies
Piece checks positive.Total effective rate for recovery from illness+it is effective.
Test group, 100, wherein man 52, female 48, the age at 15-58 Sui, is controlled using the drug of the present invention
It treats, administrated method is the same as above-mentioned.
Control group, 100, wherein man 52, female 48, age 15-58 Sui, the health azoles for using common treatment ringworm of the body is newborn
Cream is treated, and administrated method is to be smeared by its specification in the skin with fungi, 1-2 times daily, and 5 days are one
The course for the treatment of.
The basic conditions such as two groups of the case state of an illness, ages are suitable, there is comparativity.
Therapeutic effect is as follows.
Control group：Cure number of cases 31 (account for total number of cases 31.0%), effective number of cases 32 (account for total number of cases 32.0%), nothing
Imitate number of cases 37 (account for total number of cases 37.0%), total effective rate 67.0%；Experimental group：It cures number of cases 58 and (accounts for total number of cases
58.0%), effective number of cases 37 (37.0%), invalid number of cases 5 (account for total number of cases 5.0%), total effective rate 95.0%.
From the aforegoing it can be seen that the drug of the present invention is significantly better than fungal dermatopathy therapeutic effect the effect of health azoles emulsifiable paste
Fruit.
Finally it should be noted that embodiment is the optimal specific embodiment of the present invention, it is not limited to this
Invention, although the present invention is described in detail referring to the foregoing embodiments, for those skilled in the art, according to
So it can modify to the technical solution recorded in foregoing embodiments or which part technical characteristic is equally replaced
It changes.All within the spirits and principles of the present invention, any modification, equivalent replacement, improvement and so on should be included in the present invention
Protection domain within.
Claims (5)
1. a kind of composition of medicine for treating fungal dermatopathy, it includes soaking agent and applies cream, and the raw material weight of soaking agent is made
There are 1-3 parts of Sulfur, 0.5-1 parts of potassium permanganate, 1-2 parts of salicylic acid, 3-5 parts of ginger, 3-5 parts of garlic, 1-3 parts of salt than part；System
There are 1-2 parts of 5 FU 5 fluorouracil, 9-11 parts of vaseline than part into the raw material weight for applying cream.
2. composition of medicine according to claim 1, it is characterised in that it is made of following raw materials；Soaking agent：Sulfur 3
Part, 1 part of potassium permanganate, 1 part of salicylic acid, 5 parts of ginger, 5 parts of garlic, 3 parts of salt；Apply cream：2 parts of 5 FU 5 fluorouracil, vaseline 9
Part.
3. composition of medicine according to claim 1, it is characterised in that it is made of following raw materials；Soaking agent：Sulfur 1
Part, 0.5 part of potassium permanganate, 1 part of salicylic acid, 3 parts of ginger, 3 parts of garlic, 2 parts of salt；Apply cream：1 part of 5 FU 5 fluorouracil, vaseline 9
Part.
4. composition of medicine according to claim 1, it is characterised in that it is made of following raw materials；Soaking agent：Sulfur 1
Part, 1 part of potassium permanganate, 1 part of salicylic acid, 5 parts of ginger, 3 parts of garlic, 2 parts of salt；Apply cream：2 parts of 5 FU 5 fluorouracil, vaseline 11
Part.
A 5. processing method for treating fungal dermatopathy composition of medicine as described in claim 1, it is characterised in that including impregnating
The preparation process of agent and the preparation process for applying cream：
The preparation process of the soaking agent includes the following steps：
The first step：Pulverizer first will be blended in by ginger, garlic and be ground into smalls；
Second step：Sulfur, potassium permanganate, salicylic acid, ginger garlic are mixed into smalls, salt again, blender is placed in and is stirred
10 minutes -30 minutes；
Third walks：Examine the uniformity, 100 grams by weight either 200 grams or 300 grams or 500 grams of unit glass
Bottle packaging；
The preparation process for applying cream includes the following steps：
The first step：Vaseline, 5 FU 5 fluorouracil mixing are placed in blender and be stirred 10 minutes -30 minutes；
Second step：Examine the uniformity, 10 grams by weight either 20 grams or 30 grams of unit vials or plastic bottle packets
Dress.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201711491092.8A CN108126173A (en) | 2017-12-30 | 2017-12-30 | A kind of composition of medicine for treating fungal dermatopathy and preparation method thereof |
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| CN108126173A true CN108126173A (en) | 2018-06-08 |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1111984A (en) * | 1995-04-26 | 1995-11-22 | 广东医学院医药科技开发中心 | Bath lotion series with anti-inflammatory, antipruritic and antibiotic functions |
| CN101972460A (en) * | 2010-10-15 | 2011-02-16 | 孟庆巨 | Composition for treating beriberi and preparation method thereof |
| CN105287628A (en) * | 2015-11-29 | 2016-02-03 | 阮少康 | Preparation method of medicine for treating beriberi and athlete's foot |
-
2017
- 2017-12-30 CN CN201711491092.8A patent/CN108126173A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1111984A (en) * | 1995-04-26 | 1995-11-22 | 广东医学院医药科技开发中心 | Bath lotion series with anti-inflammatory, antipruritic and antibiotic functions |
| CN101972460A (en) * | 2010-10-15 | 2011-02-16 | 孟庆巨 | Composition for treating beriberi and preparation method thereof |
| CN105287628A (en) * | 2015-11-29 | 2016-02-03 | 阮少康 | Preparation method of medicine for treating beriberi and athlete's foot |
Non-Patent Citations (1)
| Title |
|---|
| 戴文英: "用硫黄水杨酸香波治疗花斑癣", 《国际皮肤性病学杂志》 * |
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Application publication date: 20180608 |