CN108126084A - A kind of Chinese medicine composition for treating flat wart and its application in dept. of dermatology - Google Patents
A kind of Chinese medicine composition for treating flat wart and its application in dept. of dermatology Download PDFInfo
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- CN108126084A CN108126084A CN201810024513.4A CN201810024513A CN108126084A CN 108126084 A CN108126084 A CN 108126084A CN 201810024513 A CN201810024513 A CN 201810024513A CN 108126084 A CN108126084 A CN 108126084A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/09—Lichens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/583—Snakes; Lizards, e.g. chameleons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/65—Amphibians, e.g. toads, frogs, salamanders or newts
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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Abstract
The present invention relates to a kind of Chinese medicine compositions for treating flat wart, it is made of 5 50 parts of lichens, 10 100 parts of dark plum, 7 70 parts of cicada slough, 15 110 parts of strangle careless, 10 100 parts of giant knotweed, 3 25 parts of house lizard, 4 20 parts of toad-cortex, 12 90 parts of Paris polyphylla, preparation is externally applied liniment, and Chinese medicine composition externally applied liniment of the present invention is used for the treatment of verruca vulgaris, herpes zoster, acne.
Description
The present invention relates to a kind of Chinese medicine composition for treating flat wart and its applications in dept. of dermatology, belong to tcm field.
Background technology
Flat wart is by human papilloma virus（HPV）Caused by infection, it is apt to occur in teen-age disease of viral infection.
Clinical manifestation is color of the leather or the flat papule of pink, is more common in face and the back of the hand, without apparent subjective symptoms, the course of disease is chronic.
Direct or indirect contagion can be passed through.Flat wart has certain infectiousness, sometimes due to scratching virus inoculation in neighbouring skin
Skin, in the linear alignment being distributed along scratch.It is general superficial, it is sometimes micro- to itch.The course of disease is slower, and what is had can spontaneous regression.Due to
Flat wart disease time is longer, easier to form serious pigmentation, and easily induces other serious consequences.Skin lesion is mainly in
Face, the back of the hand, arm show as the flat papule to differ in size, and slight to swell, surface is smooth, rounded, oval or polygonal
Shape, boundary understand, can dense distribution or due to part scratching and linear arrangement, general no conscious sympton, some patientss are felt
Slight itch.The course of disease be in chronic process, it is sustainable for many years.Retinoic acid ointment, imiquimod ointment can be used in the external used medicine of this disease
Deng treatment.Determine it is curative effect including freezing and laser therapy, the orally available isotretinoin capsule for treating of severe patient, external application Western medicine paste
Difference, particularly freezing and laser therapy, if flat wart range is too big, there is a great harm for laser and freezing generation, and easily
Lead to local infection and scar, some cleanings are not clean, and close to the place of mucous membrane eyes, be not easy to it is affected, easily
The drawbacks such as recurrence for more than medication shortcoming, invent a kind of externally applied liniment for the Chinese medicine composition for treating flat wart, and advantage is effect
Fruit is good, and application site is extensive, and whole body can be used everywhere, has no toxic side effect, simple for production, application easy to spread.
Invention content
Good the purpose of the present invention is to provide a kind of effect, application site is extensive, and whole body can be used everywhere, has no toxic side effect,
It is simple for production, the Chinese medicine composition of the treatment flat wart of application easy to spread and its application in dept. of dermatology, to overcome existing skill
The deficiency of art.
The technical solution that the present invention solves above-mentioned technical problem is as follows：
A kind of Chinese medicine preparation for treating treatment flat wart, is made of the raw material of following parts by weight：
By 5-50 parts of lichens, 10-100 parts of dark plum, 7-70 parts of cicada slough, 15-110 parts of strangle careless, 10-100 parts of giant knotweed, house lizard 3-25
Part, 4-20 parts of toad-cortex, 12-90 parts of Paris polyphylla.
As the further preferred of above-mentioned technical proposal, the composite preparation is made of the raw material of following parts by weight：
25 parts of lichens, 50 parts of dark plum, 35 parts of cicada slough, 55 parts of strangle careless, 50 parts of giant knotweed, 12 parts of house lizard, 10 parts of toad-cortex, 45 parts of Paris polyphylla.
The preparation method of the Chinese medicine composition for the treatment of flat wart as above-mentioned technical proposal includes the following steps：
A, lichens, dark plum, cicada slough, strangle careless, giant knotweed, house lizard, toad-cortex, Paris polyphylla are fully impregnated 2-3 days with 95% ethyl alcohol, flow back 1-2
Hour, filtering takes filtrate, and filter residue repeats reflux 2-3 times, and merging filtrate recycles ethyl alcohol；
B, after the placement of the filtrate of step a is cooled down, distilled water, calamine, glycerine is added in and is stirred evenly as externally applied liniment.
In the above-mentioned technical solutions, each taste Chinese medicine in compositing formula has effects that as follows：
The invention is mainly made of 8 kinds of Chinese medicines, and wherein lichens adjusts skin immune function controlling, and skin is helped to defend outer gas, enhances skin
Skin is got rid of evils ability, the anti-papillomavirus of toad-cortex, house lizard softening and resolving hard mass, skin of dispelling caking, dark plum convergence sterilizing and anti-virus, cicada slough
Expelling wind and clearing away heat, scattered subcutaneous wind-heat, strangle careless are clearing heat and detoxicating, and anti-papillomavirus, the giant knotweed powder for clearing heat and detoxicating stasis of blood, ingredient can be protected
Sheath skin is not invaded by exopathogen, it is not easy to the recurrence of this disease, Paris polyphylla be made to disappear and tie dampness removing, promote coming off for papillomavirus, Quan Fang
It shares, the interpretation of the cause, onset and process of an illness of comprehensive flat wart of hitting.Wherein, dark plum, strangle careless, giant knotweed dosage are maximum, and three shares, anti-papillomatosis
Toxic action promotes mutually, this disease is made to fully recover from an illness difficulty in relapse after healing.
The present invention is obtained from being developed, processed according to local Empirical formula, developing, and drug is made in itself that poison is not secondary
With relatively more safe and reliable, drug is with obvious effects, while its production method is simple and practicable, and Conventional processing methods carry for the present invention
Easy to operate in the production of the bulk pharmaceutical chemicals of confession, active ingredient will not lose, and raw material is easy to get.
Inventor started before the several years using technical solutions according to the invention, and more than 100 treatment flat wart for the treatment of number is suffered from
Person obtains the effect of fine.
Specific embodiment：
The first：A kind of Chinese medicine preparation for treating treatment flat wart, is made of the raw material of following parts by weight：
By 50 parts of lichens, 100 parts of dark plum, 70 parts of cicada slough, 110 parts of strangle careless, 100 parts of giant knotweed, 25 parts of house lizard, 20 parts of toad-cortex, Paris polyphylla
90 parts.
Second：A kind of Chinese medicine preparation for treating treatment flat wart, is made of the raw material of following parts by weight：
By 5 parts of lichens, 10 parts of dark plum, 7 parts of cicada slough, 15 parts of strangle careless, 10 parts of giant knotweed, 3 parts of house lizard, 4 parts of toad-cortex, 12 parts of Paris polyphylla.
The third：A kind of Chinese medicine preparation for treating treatment flat wart, is made of the raw material of following parts by weight：
25 parts of lichens, 50 parts of dark plum, 35 parts of cicada slough, 55 parts of strangle careless, 50 parts of giant knotweed, 12 parts of house lizard, 10 parts of toad-cortex, 45 parts of Paris polyphylla.
4th kind：A kind of preparation method for the Chinese medicine preparation for treating flat wart includes the following steps：By 25 parts of lichens, dark plum
50 parts, 35 parts of cicada slough, 55 parts of strangle careless, 50 parts of giant knotweed, 12 parts of house lizard, 10 parts of toad-cortex, 45 parts of Paris polyphylla fully impregnate 3 with 95% ethyl alcohol
My god, it flows back 2 hours, filtering takes filtrate, and filter residue repeats reflux 3 times, merging filtrate；Recycle ethyl alcohol；After placing cooling, add in and steam
Distilled water, calamine, glycerine stir evenly.
5th kind：A kind of preparation method for the Chinese medicine preparation for treating flat wart includes the following steps：It will be by 50 parts of lichens, crow
90 parts of 100 parts of plum, 70 parts of cicada slough, 110 parts of strangle careless, 100 parts of giant knotweed, 25 parts of house lizard, 20 parts of toad-cortex, Paris polyphylla 95% ethyl alcohol of use are abundant
It impregnates 2 days, flows back 1 hour, filtering takes filtrate, and filter residue repeats reflux 3 times, merging filtrate；Recycle ethyl alcohol；After placing cooling, add
Enter distilled water, calamine, glycerine to stir evenly.
6th kind：A kind of preparation method for the Chinese medicine preparation for treating flat wart includes the following steps：By 5 parts of lichens, 10 parts of dark plum,
7 parts of cicada slough, 15 parts of strangle careless, 10 parts of giant knotweed, 3 parts of house lizard, 4 parts of toad-cortex, 12 parts of Paris polyphylla are fully impregnated 3 days with 95% ethyl alcohol, reflux 2
Hour, filtering takes filtrate, and filter residue repeats reflux 2 times, merging filtrate；Recycle ethyl alcohol；After placing cooling, it is sweet to add in distilled water, stove
Stone, glycerine stir evenly.
Clinical practice：
1 clinical data
According to《《TCM Dermatology disease Standardization of diagnosis and curative effect》》The standard that middle verruca plana is formulated selects flat wart patient 126
Example, is randomly divided into 2 groups, invention group group（Treatment group）Group 63,17~46 years old age.Western medical treatment group（Control group）63, year
17~51 years old age, above-mentioned case derive from September, 2001 in March, 2016 after my section's outpatient service treating flat wart, completion treatment
Observation, and informed consent.
2 therapies
Control group gives Retinoic acid ointment, the treatment of outer wiping affected part.This research is exited if midway is using other drugs treatment.This hair
25 parts of lichens of bright treatment group, 50 parts of dark plum, 35 parts of cicada slough, 55 parts of strangle careless, 50 parts of giant knotweed, 12 parts of house lizard, 10 parts of toad-cortex, Paris polyphylla
45 parts of decoctings are condensed into 200mL, outer wiping affected part.
3 curative effect judging standards
According to《《TCM Dermatology disease Standardization of diagnosis and curative effect》》The effect of middle verruca plana, evaluates：
It cures：Skin lesion is subsided, and nothing newly goes out fash.
It improves：Fash flattens earlier above, and subsiding more than 30% or has indivedual new rash to occur.
It is not cured：Fash is unchanged or recession is less than 30%.
4 results
Effect is as follows after two groups of patients, 3 courses for the treatment of：
Two groups of pretherapy and post-treatment effects compare（x±s）
Group, which cures to improve, is not cured cure rate（%）
Treatment group（n =63） 56 7 0 88.89
Control group（n =63） 37 16 10 58.73
Note：Compared with after control group treatmentP<0.05。
Model case：Dept. of dermatology of the court present invention treatment verruca vulgaris 27,23 of recovery from illness, responder 4
Dept. of dermatology of the court present invention treatment acne 76, cure rate 57, effective 19, effective percentage 98%.
Dept. of dermatology of the court present invention treatment herpes zoster 2, fully recovers.
In short, treating flat wart with the invention, verruca vulgaris, acne, herpes zoster directly against the interpretation of the cause, onset and process of an illness of this disease, are treated
Effect is definite, and toxic side effect is small, is the effective ways being worthy to be popularized.
Claims (5)
1. a kind of Chinese medicine composition for treating flat wart, it is characterized in that：The Chinese medicine composition by following parts by weight raw material
It is made：
5-50 parts of lichens, 10-100 parts of dark plum, 7-70 parts of cicada slough, 15-110 parts of strangle careless, 10-100 parts of giant knotweed, 3-25 parts of house lizard,
4-20 parts of toad-cortex, 12-90 parts of Paris polyphylla.
2. the Chinese medicine composition for the treatment of flat wart as described in claim 1, it is characterized in that：The Chinese medicine composition is by following heavy
The raw material of amount part are made：
25 parts of lichens, 50 parts of dark plum, 35 parts of cicada slough, 55 parts of strangle careless, 50 parts of giant knotweed, 12 parts of house lizard, 10 parts of toad-cortex, 45 parts of Paris polyphylla.
3. the Chinese medicine composition for the treatment of flat wart as described in claim 1, it is characterized in that：The Chinese medicine composition is by following heavy
The raw material of amount part are made：
15 parts of lichens, 25 parts of dark plum, 15 parts of cicada slough, 30 parts of strangle careless, 25 parts of giant knotweed, 8 parts of house lizard, 6 parts of toad-cortex, 20 parts of Paris polyphylla.
4. the Chinese medicine composition for the treatment of flat wart as claimed in claim 1 or 2, it is characterized in that：The system of the Chinese medicine composition
Preparation Method includes the following steps：
A, lichens, dark plum, cicada slough, strangle careless, giant knotweed, house lizard, toad-cortex, Paris polyphylla are fully impregnated 2-3 days with 95% ethyl alcohol, flow back 1-2
Hour, filtering takes filtrate, and filter residue repeats reflux 2-3 times, and merging filtrate recycles ethyl alcohol；
B, after the filtrate of step a being placed cooling, distilled water, calamine, glycerine is added in and is stirred evenly as externally applied liniment.
5. the Chinese medicine composition for the treatment of flat wart as claimed in claim 4, it is characterized in that：The Chinese medicine composition is for ordinary
The treatment of wart, herpes zoster, acne.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810024513.4A CN108126084A (en) | 2018-01-11 | 2018-01-11 | A kind of Chinese medicine composition for treating flat wart and its application in dept. of dermatology |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810024513.4A CN108126084A (en) | 2018-01-11 | 2018-01-11 | A kind of Chinese medicine composition for treating flat wart and its application in dept. of dermatology |
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| CN108126084A true CN108126084A (en) | 2018-06-08 |
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| CN201810024513.4A Withdrawn CN108126084A (en) | 2018-01-11 | 2018-01-11 | A kind of Chinese medicine composition for treating flat wart and its application in dept. of dermatology |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1352950A (en) * | 2000-11-03 | 2002-06-12 | 周主宝 | Liquid medicine for treating wound and sore and its preparing process |
| WO2012028758A1 (en) * | 2010-08-31 | 2012-03-08 | Servicio Andaluz De Salud | Use of crassula for treating proliferative diseases |
| CN102552492A (en) * | 2012-01-12 | 2012-07-11 | 山东省千佛山医院 | Traditional Chinese medicinal composition for treating herpes zoster and preparation method thereof |
| CN105878581A (en) * | 2016-05-26 | 2016-08-24 | 孙明香 | Liquid traditional Chinese medicine for treating verruca plana and preparation method thereof |
-
2018
- 2018-01-11 CN CN201810024513.4A patent/CN108126084A/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1352950A (en) * | 2000-11-03 | 2002-06-12 | 周主宝 | Liquid medicine for treating wound and sore and its preparing process |
| WO2012028758A1 (en) * | 2010-08-31 | 2012-03-08 | Servicio Andaluz De Salud | Use of crassula for treating proliferative diseases |
| CN102552492A (en) * | 2012-01-12 | 2012-07-11 | 山东省千佛山医院 | Traditional Chinese medicinal composition for treating herpes zoster and preparation method thereof |
| CN105878581A (en) * | 2016-05-26 | 2016-08-24 | 孙明香 | Liquid traditional Chinese medicine for treating verruca plana and preparation method thereof |
Non-Patent Citations (4)
| Title |
|---|
| 张学贵: "《中医集承续辑》", 30 June 2015, 内蒙古科学技术出版社 * |
| 张浩良: "蛇伤急救良药——季德胜蛇药片新用", 《中国中医急症》 * |
| 苏南湘: ""虎梅颗粒剂治疗带状疱疹32例", 《湖南中医杂志》 * |
| 马汴梁: "《常见病中医小方手册》", 31 March 2014, 金盾出版社 * |
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Application publication date: 20180608 |