CN105878581A - Liquid traditional Chinese medicine for treating verruca plana and preparation method thereof - Google Patents
Liquid traditional Chinese medicine for treating verruca plana and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/748—Oldenlandia or Hedyotis
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/33—Cactaceae (Cactus family), e.g. pricklypear or Cereus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/41—Crassulaceae (Stonecrop family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Abstract
The invention discloses a liquid traditional Chinese medicine for treating verruca plana and a preparation method thereof. The liquid traditional Chinese medicine is prepared from the following traditional Chinese medicinal raw materials in parts by weight: 15-25 parts of oldenlandia diffusa, 15-25 parts of opuntia stricta, 10-20 parts of herba portulacae, 10-20 parts of salvia miltiorrhiza, 10-20 parts of clerodendrum bungei, 5-15 parts of sedum lineare, 5-15 parts of radix semiaquilegiae, 5-15 parts of flos sophorae, 4-12 parts of frankincense, 2-8 parts of periostracum cicada, 2-8 parts of peppermint and 0.02-0.06 part of cantharides. The liquid traditional Chinese medicine is prepared by adopting common traditional Chinese medicinal materials as raw materials, is convenient in administration route, quick in response and low in cost, does not have irritation, toxic or side effect, has remarkable curative effect, prevents scar or relapse, has the effects of clearing heat, removing toxicity, nourishing blood, dispelling wind, regulating liver, strengthening spleen, softening hard mass and removing verruca, and can be used for quickly and effectively treating verruca plana.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of herb liquid treating verruca plana and preparation method thereof.
Background technology
Verruca plana is a kind of viral dermatosis, is apt to occur in teenager.It is to be felt by papillomavirus HPV3 and HPV5
The skin vegetations that causes of dye, shows as dispersed and distributed, quality is soft, top is smooth, foxtail millet grain to Semen phaseoli radiati is big, hazel exceeds
The flat pimple of skin surface.It is apt to occur in the exposure portion such as face, the back of the hand portion, there is certain infectiousness, and the course of disease is slow
Property, can suddenly disappearing after several weeks or several months, it is possible to lasting for years does not heals, disease time is the longest, and verruca plana is more easily formed seriously
Pigmentation, and other serious consequence can be induced, therefore should treat in time.
Western medical treatment verruca plana is many using hormone, antibiotic, vitamin as common drug, even uses laser, liquid nitrogen cold
Freeze treatment etc., but these therapies have relatively strong stimulation to skin, grasp the bad cicatrix that easily stays, and there is the biggest side effect and peace
Full hidden danger, relapse rate is high.The traditional Chinese medical science think wart belong to ailment said due to cold or exposure visitor in skin superfluous raw or dry because of deficiency of the liver, muscle do not seek caused reason
Opinion, uses traditional Chinese medical science global theory and determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs rule, and Chinese medicine is mostly to adjust liver spleen, nourishing blood to expel wind, heat-clearing and toxic substances removing, softening the hard mass to remove
Wart is Therapeutic Principle.In existing patent document, Authorization Notice No. CN102688393B(application number 201210139938.2)
Chinese patent literature disclose a kind of Chinese medicine treating verruca plana and preparation method thereof, its main raw material is: the Radix Angelicae Dahuricae, Dens Equi
Herba Amaranthi tricoloris, Polyporus, the Radix Astragali, Rhizoma Dioscoreae esculentae leaf, Aloe, Rhizoma Phragmitis, Radix Saposhnikoviae, Herba Moslae, Flos Chrysanthemi, Herba Schizonepetae, Folium Perillae, Folium Mori, Flos Lonicerae, Herba Taraxaci, purple
Flower Herba Violae, Herba Patriniae, Radix Angelicae Sinensis, carbonized Fructus Mume, Radix Paeoniae Rubra, Herba Menthae, Caulis Sargentodoxae, Herba Andrographis, Herba Houttuyniae, Rhizoma Coptidis, Radix Scutellariae, Radix Gentianae, Radix Sophorae Flavescentis,
Folium Mahoniae, Cortex Phellodendri, Radix Arnebiae (Radix Lithospermi), Radix Sanguisorbae, Cortex Moutan and Radix Scrophulariae.
Although there is the Chinese medicine of more treatment verruca plana at present, and there is certain curative effect, but some drugs is still
There is the problems such as raw material is many, cost is high, take inconvenience, onset is slow.
Summary of the invention
An object of the present invention is to overcome the deficiencies in the prior art, it is provided that a kind of low cost, rapid-action, non-stimulated, nothing
Toxic and side effects, evident in efficacy, it is difficult to the herb liquid of the treatment verruca plana of recurrence.
In order to solve above-mentioned technical problem, the technical solution adopted in the present invention is:
A kind of herb liquid treating verruca plana, takes off and states the raw material of Chinese medicine of weight proportion and be prepared from: Herba Hedyotidis Diffusae 15-25
Part, Radix et Caulis Opuntiae Dillenii 15-25 part, Herba Portulacae 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Caulis et folium clerodendri bungei 10-20 part, Herba Sedi Linearis 5-15 part, Radix Semiaquilegiae
5-15 part, Flos Sophorae 5-15 part, Olibanum 4-12 part, Periostracum Cicadae 2-8 part, Herba Menthae 2-8 part, Mylabris 0.02-0.06 part.
A kind of herb liquid treating verruca plana, preferred scheme, take off and state the raw material of Chinese medicine of weight proportion and be prepared from: be white
Serpentis SHECAO 18-22 part, Radix et Caulis Opuntiae Dillenii 18-22 part, Herba Portulacae 13-17 part, Radix Salviae Miltiorrhizae 13-17 part, Caulis et folium clerodendri bungei 13-17 part, Herba Sedi Linearis
8-12 part, Radix Semiaquilegiae 8-12 part, Flos Sophorae 8-12 part, Olibanum 6-10 part, Periostracum Cicadae 4-6 part, Herba Menthae 4-6 part, Mylabris 0.03-0.05
Part.
A kind of herb liquid treating verruca plana, scheme more preferably, take off state weight proportion raw material of Chinese medicine preparation and
Become: Herba Hedyotidis Diffusae 20 parts, Radix et Caulis Opuntiae Dillenii 20 parts, Herba Portulacae 15 parts, Radix Salviae Miltiorrhizae 15 parts, Caulis et folium clerodendri bungei 15 parts, Herba Sedi Linearis 10 parts, Radix Semiaquilegiae
10 parts, 10 parts of Flos Sophorae, Olibanum 8 parts, Periostracum Cicadae 5 parts, Herba Menthae 5 parts, Mylabris 0.04 part.
It is a further object of the present invention to provide the preparation method of the herb liquid of above-mentioned treatment verruca plana.
A kind of preparation method of the herb liquid treating verruca plana, step is as follows:
Step one: after Herba Hedyotidis Diffusae, Radix et Caulis Opuntiae Dillenii, Herba Sedi Linearis remove impurity respectively, cleaning, smash to pieces, get it filled with double gauze extruding
Juice, standby；
Step 2: by the respectively remove impurity of Periostracum Cicadae, Mylabris, clean, dried, be crushed to the fine powder of 120 mesh, standby；
Step 3: by the respectively remove impurity of Herba Portulacae, Radix Salviae Miltiorrhizae, Caulis et folium clerodendri bungei, Radix Semiaquilegiae, Flos Sophorae, Olibanum, Herba Menthae, clean, dried, powder
It is broken to the coarser powder of 40 mesh, is subsequently adding the ethanol that volume fraction is 75-85% of raw material weight 6-10 times, under the conditions of 60-70 DEG C
Heating and refluxing extraction 1-2h, obtains ethanol extract, uses filter coarse filtration, then use ultrafilter fine straining, obtain fine straining after room temperature
Liquid, standby；
Step 4: the fine straining liquid in step 3 is evaporated under the conditions of 60 DEG C the concentrated solution of 30-50%, is subsequently adding step
The fine powder that rapid one medicine juice obtained obtains with step 2, after mix homogeneously, sterilizing, bottle and i.e. obtain the herb liquid for the treatment of verruca plana.
The preparation method of the herb liquid of above-mentioned treatment verruca plana, adds the volume fraction of raw material weight 7-9 times in step 3
For the ethanol of 78-82%, heating and refluxing extraction 1.3-1.7h under the conditions of 63-67 DEG C, obtain ethanol extract；Preferably, add
The volume fraction that raw material weight is 8 times is the ethanol of 80%, and heating and refluxing extraction 1.5h under the conditions of 65 DEG C obtains ethanol extract.
The preparation method of the herb liquid of above-mentioned treatment verruca plana, by the fine straining liquid in step 3 60 DEG C of conditions in step 4
Under be evaporated to the concentrated solution of 35-45%；Preferably, the fine straining liquid in step 3 is evaporated to 40% under the conditions of 60 DEG C
Concentrated solution.
The present invention treats the using method of the herb liquid of verruca plana: herb liquid of the present invention is applied in affected part, each 5-
10mL, three times a day, 5 days is a course for the treatment of.
Used by the present invention, the pharmacology of main raw material of Chinese medicine is as follows:
Herba Hedyotidis Diffusae: mildly bitter flavor, micro-sweet, cool in nature.Return stomach warp, large intestine channel, small intestine meridian.Effect and effect: heat clearing away, dampness removing, solution
Malicious, anticancer.There is antitumor, strengthen immunity, adrenal cortex reinforcing function and the effect such as antiulcer, suppression spermatogenesis.With controlling lung-heat
Breath with cough, laryngopharynx swelling and pain；Jaundice due to damp-heat, gastritis, cholecystitis, cholelithiasis；Enteritis, dysentery, pyelonephritis, urethritis, pelvic inflammatory disease；Heat
Skin infection infections, lung abscess, acute appendicitis, venom.
Radix et Caulis Opuntiae Dillenii: cold in nature, bitter in the mouth.Return stomach warp.Effect and effect: promoting flow of QI and blood, cooling blood for hemostasis, removing toxic substances and promoting subsidence of swelling.Cure mainly stomach
Bitterly, mass in the abdomen, dysentery, laryngalgia, cough due to lung-heat, pulmonary tuberculosis spitting of blood, haematemesis, hemorrhoidal bleeding, skin infection, acute mastitis, mumps, tinea, snake bite and insect sting, scald
Wound and cold injury.
Herba Portulacae: sour in the mouth, cold in nature.Return large intestine channel, Liver Channel.Effect and effect: heat-clearing and toxic substances removing, cooling blood for hemostasis.With control enteritis,
Bacillary dysentery, furuncle swelling toxin, snake bite and insect sting, swelling and pain of hemorrhoid, eczema, acute dermatitis, subacute dermatitis, herpes zoster, puerperal and function
Temper official is hemorrhage, appendicitis, ancylostomiasis.
Radix Salviae Miltiorrhizae: cold nature, bitter in the mouth.GUIXIN warp, Liver Channel.Effect and effect: stasis-dispelling and pain-killing, dysmenorrhea of invigorating blood circulation, clear away heart-fire relieving restlessness.With
Control menoxenia, amenorrhea dysmenorrhea, abdominal mass accumulation, chest and abdomen twinge, pyretic arthralgia pain, sore swollen toxin, dysphoria and insomnia；Hepatosplenomegaly, the heart
Angor.
Caulis et folium clerodendri bungei: property is put down, bitter in the mouth, pungent.GUIXIN warp, stomach warp, large intestine channel.Effect and effect: expelling wind and removing dampness, suppressing the hyperactive liver and subsiding YANG,
Subduing swelling and detoxicating.For carbuncle, furuncle, mastitis, arthritis, eczema, toothache, hemorrhoid, proctoptosis, uterine prolapse.
Herba Sedi Linearis: cold in nature, sweet in the mouth.GUIXIN warp, lung meridian, Liver Channel, spleen channel.Effect and effect: heat-clearing and toxic substances removing.With controlling pyretic toxicity
YANG syndrome toxic swelling and soup burn and scald, the venoms such as caused laryngopharynx swelling and pain, carbuncle, furuncle, erysipelas.
Radix Semiaquilegiae: cold in nature, sweet in the mouth, hardship, return liver, stomach warp.Effect and effect: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Stop up with controlling pyretic toxicity
Carbuncle furuncle caused by knot, scrofula, hemorrhoid, and hernia, treating swelling and pain by traumatic injury, venom etc..
Flos Sophorae: bitter in the mouth, cold nature, returns liver, large intestine channel；Entering blood and hold back fall, body slightly dissipates；There is cooling blood for hemostasis, purging liver-fire
Effect；Cure mainly discharging fresh blood stool, hemorrhoidal bleeding, dysentery, hematuria, stranguria with blood, metrorrhagia, spit blood, epistaxis, liver-fire headache, conjunctival congestion and swelling pain, larynx
Numbness, aphonia, ulcer sores.
Olibanum: warm in nature, acrid in the mouth, hardship.GUIXIN warp, spleen channel, Liver Channel.Effect and effect: regulating qi and activating blood, analgesic therapy, subside a swelling, raw
Flesh.With controlling stagnation of QI-blood, trusted subordinate's pain, ulcerative carbuncle toxic swelling, traumatic injury, rheumatic arthralgia, dysmenorrhea, postnatal blood stasis twinge.
Periostracum Cicadae: cold in nature, sweet in the mouth.Return lung meridian, Liver Channel.Effect and effect: dissipate wind heat extraction, sore-throat relieving rash, spasmolytic, nebula removing.With
Control anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, cataract, convulsion with spasms, tetanus.
Herba Menthae: cool in nature, acrid in the mouth.Return lung meridian, Liver Channel.Effect and effect: dispelling wind-heat, refresh oneself, rash.With the wind that cures cold
Heat, headache, conjunctival congestion, red swelling and pain of throat, skin pruritus, measles without adequate eruption etc..
Mylabris: property heat, acrid in the mouth, very toxic.Return Liver Channel, stomach warp, kidney channel.Effect and effect: removing blood stasis disappears, counteracting toxic substances phagedenoma,
Draw red foaming.With controlling abdominal mass lump, for many years stubborn dermatitis, scrofula, wart, carbuncle are not burst.
Compared with prior art, the invention have the benefit that
The present invention treats the herb liquid of verruca plana, uses common Chinese medicine material as raw material, and route of administration is convenient, rapid-action, cost
Low, non-stimulated, have no side effect, evident in efficacy, do not stay scar, be difficult to recurrence, have heat-clearing and toxic substances removing, nourishing blood to expel wind, tune liver spleen,
Softening the hard mass, except effect of wart, can treat verruca plana fast and effectively.
Detailed description of the invention
Describe technical scheme in detail below in conjunction with embodiment and experimental example, but protection domain is not limited by this.
Embodiment 1 one kinds treats the herb liquid of verruca plana, takes off and states the raw material of Chinese medicine of weight proportion and be prepared from that (every part takes
1g): Herba Hedyotidis Diffusae 15 parts, Radix et Caulis Opuntiae Dillenii 15 parts, Herba Portulacae 10 parts, Radix Salviae Miltiorrhizae 10 parts, Caulis et folium clerodendri bungei 10 parts, Herba Sedi Linearis 5 parts, Radix Semiaquilegiae
5 parts, 5 parts of Flos Sophorae, Olibanum 4 parts, Periostracum Cicadae 2 parts, Herba Menthae 2 parts, Mylabris 0.02 part.
The preparation method of the herb liquid of above-mentioned treatment verruca plana, step is as follows:
Step one: after Herba Hedyotidis Diffusae, Radix et Caulis Opuntiae Dillenii, Herba Sedi Linearis remove impurity respectively, cleaning, smash to pieces, get it filled with double gauze extruding
Juice, standby；
Step 2: by the respectively remove impurity of Periostracum Cicadae, Mylabris, clean, dried, be crushed to the fine powder of 120 mesh, standby；
Step 3: by the respectively remove impurity of Herba Portulacae, Radix Salviae Miltiorrhizae, Caulis et folium clerodendri bungei, Radix Semiaquilegiae, Flos Sophorae, Olibanum, Herba Menthae, clean, dried, powder
It is broken to the coarser powder of 40 mesh, is subsequently adding the ethanol that volume fraction is 75% of raw material weight 6 times, is heated to reflux under the conditions of 60 DEG C
Extract 1h, obtain ethanol extract, after room temperature, use filter coarse filtration, then use ultrafilter fine straining, obtain fine straining liquid, standby；
Step 4: the fine straining liquid in step 3 is evaporated under the conditions of 60 DEG C the concentrated solution of 30%, is subsequently adding step one
The fine powder that the medicine juice obtained and step 2 obtain, after mix homogeneously, sterilizing, bottle and i.e. obtain the herb liquid for the treatment of verruca plana.
Embodiment 2 one kinds treats the herb liquid of verruca plana, takes off and states the raw material of Chinese medicine of weight proportion and be prepared from that (every part takes
1g): Herba Hedyotidis Diffusae 25 parts, Radix et Caulis Opuntiae Dillenii 25 parts, Herba Portulacae 20 parts, Radix Salviae Miltiorrhizae 20 parts, Caulis et folium clerodendri bungei 20 parts, Herba Sedi Linearis 15 parts, Radix Semiaquilegiae
Son 15 parts, 15 parts of Flos Sophorae, Olibanum 12 parts, Periostracum Cicadae 8 parts, Herba Menthae 8 parts, Mylabris 0.06 part.
The preparation method of the herb liquid of above-mentioned treatment verruca plana, step is as follows:
Step one: after Herba Hedyotidis Diffusae, Radix et Caulis Opuntiae Dillenii, Herba Sedi Linearis remove impurity respectively, cleaning, smash to pieces, get it filled with double gauze extruding
Juice, standby；
Step 2: by the respectively remove impurity of Periostracum Cicadae, Mylabris, clean, dried, be crushed to the fine powder of 120 mesh, standby；
Step 3: by the respectively remove impurity of Herba Portulacae, Radix Salviae Miltiorrhizae, Caulis et folium clerodendri bungei, Radix Semiaquilegiae, Flos Sophorae, Olibanum, Herba Menthae, clean, dried, powder
It is broken to the coarser powder of 40 mesh, is subsequently adding the ethanol that volume fraction is 85% of raw material weight 10 times, is heated to reflux under the conditions of 70 DEG C
Extract 2h, obtain ethanol extract, after room temperature, use filter coarse filtration, then use ultrafilter fine straining, obtain fine straining liquid, standby；
Step 4: the fine straining liquid in step 3 is evaporated under the conditions of 60 DEG C the concentrated solution of 50%, is subsequently adding step one
The fine powder that the medicine juice obtained and step 2 obtain, after mix homogeneously, sterilizing, bottle and i.e. obtain the herb liquid for the treatment of verruca plana.
Model case one: week xx, female, 16 years old, student.Readme: the multiple verruca plana of face, the back of the hand, forearm, shirtfront etc.,
Once oral Chinese medicine treatment, without positive effect.To examination in hospital: general health check-up is without exception.Only forehead and the both hands back of the body, forearm, front
Breast is all visible, quality is soft, top is smooth, foxtail millet grain to Semen phaseoli radiati is big, be slightly higher than the filbert flat pimple of surface, and edge boundary is clear
Chu, NIP, it is dispersed in scratch and has accompanied a small amount of blood crusts skin lesion.Stringy and thready pulse is several.Tongue fur color is the most greasy, while there is indentation.It is diagnosed
For verruca plana.
After using the herb liquid in the embodiment of the present invention 2 to treat 1 course for the treatment of, pimple infringement takes a favorable turn, and verruca plana comes off,
After continual cure 2 course for the treatment of, symptom is wholly absent, recovery from illness, and does not stays cicatrix.Pay a return visit after 1 year and do not recur.
Embodiment 3 one kinds treats the herb liquid of verruca plana, takes off and states the raw material of Chinese medicine of weight proportion and be prepared from that (every part takes
1g): Herba Hedyotidis Diffusae 18 parts, Radix et Caulis Opuntiae Dillenii 18 parts, Herba Portulacae 13 parts, Radix Salviae Miltiorrhizae 13 parts, Caulis et folium clerodendri bungei 13 parts, Herba Sedi Linearis 8 parts, Radix Semiaquilegiae
8 parts, 8 parts of Flos Sophorae, Olibanum 6 parts, Periostracum Cicadae 4 parts, Herba Menthae 4 parts, Mylabris 0.03 part.
The preparation method of the herb liquid of above-mentioned treatment verruca plana, step is as follows:
Step one: after Herba Hedyotidis Diffusae, Radix et Caulis Opuntiae Dillenii, Herba Sedi Linearis remove impurity respectively, cleaning, smash to pieces, get it filled with double gauze extruding
Juice, standby；
Step 2: by the respectively remove impurity of Periostracum Cicadae, Mylabris, clean, dried, be crushed to the fine powder of 120 mesh, standby；
Step 3: by the respectively remove impurity of Herba Portulacae, Radix Salviae Miltiorrhizae, Caulis et folium clerodendri bungei, Radix Semiaquilegiae, Flos Sophorae, Olibanum, Herba Menthae, clean, dried, powder
It is broken to the coarser powder of 40 mesh, is subsequently adding the ethanol that volume fraction is 78% of raw material weight 7 times, is heated to reflux under the conditions of 63 DEG C
Extract 1.3h, obtain ethanol extract, after room temperature, use filter coarse filtration, then use ultrafilter fine straining, obtain fine straining liquid, standby；
Step 4: the fine straining liquid in step 3 is evaporated under the conditions of 60 DEG C the concentrated solution of 35%, is subsequently adding step one
The fine powder that the medicine juice obtained and step 2 obtain, after mix homogeneously, sterilizing, bottle and i.e. obtain the herb liquid for the treatment of verruca plana.
Embodiment 4 one kinds treats the herb liquid of verruca plana, takes off and states the raw material of Chinese medicine of weight proportion and be prepared from that (every part takes
1g): Herba Hedyotidis Diffusae 22 parts, Radix et Caulis Opuntiae Dillenii 22 parts, Herba Portulacae 17 parts, Radix Salviae Miltiorrhizae 17 parts, Caulis et folium clerodendri bungei 17 parts, Herba Sedi Linearis 12 parts, Radix Semiaquilegiae
Son 12 parts, 12 parts of Flos Sophorae, Olibanum 10 parts, Periostracum Cicadae 6 parts, Herba Menthae 6 parts, Mylabris 0.05 part.
The preparation method of the herb liquid of above-mentioned treatment verruca plana, step is as follows:
Step one: after Herba Hedyotidis Diffusae, Radix et Caulis Opuntiae Dillenii, Herba Sedi Linearis remove impurity respectively, cleaning, smash to pieces, get it filled with double gauze extruding
Juice, standby；
Step 2: by the respectively remove impurity of Periostracum Cicadae, Mylabris, clean, dried, be crushed to the fine powder of 120 mesh, standby；
Step 3: by the respectively remove impurity of Herba Portulacae, Radix Salviae Miltiorrhizae, Caulis et folium clerodendri bungei, Radix Semiaquilegiae, Flos Sophorae, Olibanum, Herba Menthae, clean, dried, powder
It is broken to the coarser powder of 40 mesh, is subsequently adding the ethanol that volume fraction is 82% of raw material weight 9 times, is heated to reflux under the conditions of 67 DEG C
Extract 1.7h, obtain ethanol extract, after room temperature, use filter coarse filtration, then use ultrafilter fine straining, obtain fine straining liquid, standby；
Step 4: the fine straining liquid in step 3 is evaporated under the conditions of 60 DEG C the concentrated solution of 45%, is subsequently adding step one
The fine powder that the medicine juice obtained and step 2 obtain, after mix homogeneously, sterilizing, bottle and i.e. obtain the herb liquid for the treatment of verruca plana.
Model case two: cattle xx, man, 20 years old, people from Jinan.Main suit occurs distributing without obvious inducement the back of the hand portion and cheekbone portion skin
The little pimple of property, rash shape mostly is ellipse circular, flat, such as Semen Sesami size, light brown.Pruritus, right cheekbone portion is accidentally had to have several pimple
Aobvious linear array, once took multiple Western medicine and symptom fails to improve.Examination in hospital is diagnosed as verruca plana.Doctor gives its present invention
Herb liquid treatment in embodiment 4, wart body variable color after a week, incrustation, come off after two weeks, stay pigmentation, fully recover from an illness completely after three weeks
More, skin smooth, does not stays cicatrix, follows up a case by regular visits to afterwards without recurrence.
Embodiment 5 one kinds treats the herb liquid of verruca plana, takes off and states the raw material of Chinese medicine of weight proportion and be prepared from that (every part takes
1g): Herba Hedyotidis Diffusae 20 parts, Radix et Caulis Opuntiae Dillenii 20 parts, Herba Portulacae 15 parts, Radix Salviae Miltiorrhizae 15 parts, Caulis et folium clerodendri bungei 15 parts, Herba Sedi Linearis 10 parts, Radix Semiaquilegiae
Son 10 parts, 10 parts of Flos Sophorae, Olibanum 8 parts, Periostracum Cicadae 5 parts, Herba Menthae 5 parts, Mylabris 0.04 part.
The preparation method of the herb liquid of above-mentioned treatment verruca plana, step is as follows:
Step one: after Herba Hedyotidis Diffusae, Radix et Caulis Opuntiae Dillenii, Herba Sedi Linearis remove impurity respectively, cleaning, smash to pieces, get it filled with double gauze extruding
Juice, standby；
Step 2: by the respectively remove impurity of Periostracum Cicadae, Mylabris, clean, dried, be crushed to the fine powder of 120 mesh, standby；
Step 3: by the respectively remove impurity of Herba Portulacae, Radix Salviae Miltiorrhizae, Caulis et folium clerodendri bungei, Radix Semiaquilegiae, Flos Sophorae, Olibanum, Herba Menthae, clean, dried, powder
It is broken to the coarser powder of 40 mesh, is subsequently adding the ethanol that volume fraction is 80% of raw material weight 8 times, is heated to reflux under the conditions of 65 DEG C
Extract 1.5h, obtain ethanol extract, after room temperature, use filter coarse filtration, then use ultrafilter fine straining, obtain fine straining liquid, standby；
Step 4: the fine straining liquid in step 3 is evaporated under the conditions of 60 DEG C the concentrated solution of 40%, is subsequently adding step one
The fine powder that the medicine juice obtained and step 2 obtain, after mix homogeneously, sterilizing, bottle and i.e. obtain the herb liquid for the treatment of verruca plana.
Experimental example: 1, selection of clinical: in order to verify that the present invention treats the effect of the herb liquid of verruca plana, we extract
200 verruca plana patients have carried out the experiment of medicine, are equally divided into two groups, experimental group and matched group, and two groups at age, clinical table
Now etc. aspect there was no significant difference through statistical analysis.
2, Therapeutic Method:
Experimental group: use the present invention to treat the herb liquid of verruca plana.
Matched group: phthiobuzonum liniment.
3, curative effect situation criterion: after treating 1 month, cures: skin lesion disappears completely, and skin recovers normal；Effective: to damage
Evil disappears more than 60%, damages partial disappearance；Invalid: clinical symptoms is without improving or having deterioration.
Accurately the data of two groups of experiments are added up and mathematical analysis, obtain specific experiment result such as following table:
Clinical tests prove that, use the present invention to treat the herb liquid of verruca plana compared with phthiobuzonum liniment treatment verruca plana, tool
Have rapid-action, low cost, non-stimulated, have no side effect, evident in efficacy, do not stay scar, be difficult to recurrence advantage, through clinical trial demonstrate,prove
Bright, the effective percentage of herb liquid of the present invention treatment is 99%, can effectively treat verruca plana.
Claims (8)
1. the herb liquid treating verruca plana, it is characterised in that: take off and state the raw material of Chinese medicine of weight proportion and be prepared from: spend in vain
Herba Hedyotidis Diffusae 15-25 part, Radix et Caulis Opuntiae Dillenii 15-25 part, Herba Portulacae 10-20 part, Radix Salviae Miltiorrhizae 10-20 part, Caulis et folium clerodendri bungei 10-20 part, Herba Sedi Linearis 5-
15 parts, Radix Semiaquilegiae 5-15 part, Flos Sophorae 5-15 part, Olibanum 4-12 part, Periostracum Cicadae 2-8 part, Herba Menthae 2-8 part, Mylabris 0.02-0.06 part.
A kind of herb liquid treating verruca plana the most according to claim 1, it is characterised in that: take off and state in weight proportion
Medicine raw material is prepared from: Herba Hedyotidis Diffusae 18-22 part, Radix et Caulis Opuntiae Dillenii 18-22 part, Herba Portulacae 13-17 part, Radix Salviae Miltiorrhizae 13-17 part, smelly male
Red 13-17 part, Herba Sedi Linearis 8-12 part, Radix Semiaquilegiae 8-12 part, Flos Sophorae 8-12 part, Olibanum 6-10 part, Periostracum Cicadae 4-6 part, Herba Menthae 4-6
Part, Mylabris 0.03-0.05 part.
A kind of herb liquid treating verruca plana the most according to claim 1, it is characterised in that: take off and state in weight proportion
Medicine raw material is prepared from: Herba Hedyotidis Diffusae 20 parts, Radix et Caulis Opuntiae Dillenii 20 parts, Herba Portulacae 15 parts, Radix Salviae Miltiorrhizae 15 parts, Caulis et folium clerodendri bungei 15 parts, Herba Sedi Linearis
Grass 10 parts, Radix Semiaquilegiae 10 parts, 10 parts of Flos Sophorae, Olibanum 8 parts, Periostracum Cicadae 5 parts, Herba Menthae 5 parts, Mylabris 0.04 part.
4. the preparation method according to the herb liquid of the treatment verruca plana described in any one of claim 1-3, it is characterised in that:
Step is as follows:
Step one: after Herba Hedyotidis Diffusae, Radix et Caulis Opuntiae Dillenii, Herba Sedi Linearis remove impurity respectively, cleaning, smash to pieces, get it filled with double gauze extruding
Juice, standby；
Step 2: by the respectively remove impurity of Periostracum Cicadae, Mylabris, clean, dried, be crushed to the fine powder of 120 mesh, standby；
Step 3: by the respectively remove impurity of Herba Portulacae, Radix Salviae Miltiorrhizae, Caulis et folium clerodendri bungei, Radix Semiaquilegiae, Flos Sophorae, Olibanum, Herba Menthae, clean, dried, powder
It is broken to the coarser powder of 40 mesh, is subsequently adding the ethanol that volume fraction is 75-85% of raw material weight 6-10 times, under the conditions of 60-70 DEG C
Heating and refluxing extraction 1-2h, obtains ethanol extract, uses filter coarse filtration, then use ultrafilter fine straining, obtain fine straining after room temperature
Liquid, standby；
Step 4: the fine straining liquid in step 3 is evaporated under the conditions of 60 DEG C the concentrated solution of 30-50%, is subsequently adding step
The fine powder that rapid one medicine juice obtained obtains with step 2, after mix homogeneously, sterilizing, bottle and i.e. obtain the herb liquid for the treatment of verruca plana.
The preparation method of a kind of herb liquid treating verruca plana the most according to claim 4, it is characterised in that: in step 3
Add the ethanol that volume fraction is 78-82% of raw material weight 7-9 times, heating and refluxing extraction 1.3-under the conditions of 63-67 DEG C
1.7h, obtains ethanol extract.
The preparation method of a kind of herb liquid treating verruca plana the most according to claim 5, it is characterised in that: in step 3
Add the ethanol that volume fraction is 80% of raw material weight 8 times, heating and refluxing extraction 1.5h under the conditions of 65 DEG C, obtain ethanol and carry
Take liquid.
The preparation method of a kind of herb liquid treating verruca plana the most according to claim 4, it is characterised in that: in step 4
Fine straining liquid in step 3 is evaporated under the conditions of 60 DEG C the concentrated solution of 35-45%.
The preparation method of a kind of herb liquid treating verruca plana the most according to claim 7, it is characterised in that: in step 4
Fine straining liquid in step 3 is evaporated under the conditions of 60 DEG C the concentrated solution of 40%.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108126084A (en) * | 2018-01-11 | 2018-06-08 | 孙鲁娜 | A kind of Chinese medicine composition for treating flat wart and its application in dept. of dermatology |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103432526A (en) * | 2013-08-29 | 2013-12-11 | 石欣 | External use medicine for treating plane warts |
| CN103611018A (en) * | 2013-10-31 | 2014-03-05 | 山西忻州兴华皮肤病专科医院 | Traditional Chinese medicine preparation for treating verruca plana |
| CN105125975A (en) * | 2015-09-29 | 2015-12-09 | 成都倍加特生物科技有限公司 | Internal administration medicament for treating verruca plana and preparation method thereof |
| CN105343244A (en) * | 2015-12-03 | 2016-02-24 | 王亚鹤 | External medicine composition for treating verruca plana and application of external medicine composition |
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2016
- 2016-05-26 CN CN201610354874.6A patent/CN105878581A/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103432526A (en) * | 2013-08-29 | 2013-12-11 | 石欣 | External use medicine for treating plane warts |
| CN103611018A (en) * | 2013-10-31 | 2014-03-05 | 山西忻州兴华皮肤病专科医院 | Traditional Chinese medicine preparation for treating verruca plana |
| CN105125975A (en) * | 2015-09-29 | 2015-12-09 | 成都倍加特生物科技有限公司 | Internal administration medicament for treating verruca plana and preparation method thereof |
| CN105343244A (en) * | 2015-12-03 | 2016-02-24 | 王亚鹤 | External medicine composition for treating verruca plana and application of external medicine composition |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108126084A (en) * | 2018-01-11 | 2018-06-08 | 孙鲁娜 | A kind of Chinese medicine composition for treating flat wart and its application in dept. of dermatology |
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