CN108114092A - A kind of Chinese medicine composition and method for treatment nasal obstruction - Google Patents
A kind of Chinese medicine composition and method for treatment nasal obstruction Download PDFInfo
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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Abstract
It is made the invention discloses a kind of for treating the Chinese medicine composition of nasal obstruction and method, Chinese medicine composition of the substance of following quality：Withered and yellow 20 30 grams of a kind of reed mentioned in ancient books, 20 30 grams of Chinese violet, 58 grams of licorice, 15 grams of ephedrine, 1.5 3 grams of nipalgin, the preparation method of the Chinese medicine composition are：Withered and yellow 20 30 grams of a kind of reed mentioned in ancient books, 20 30 grams of Chinese violet, 58 grams of licorice are taken, is filtered after decocting one hour, takes filter liquor；Residue is dissolved to decoction again to filter within one hour, takes filter liquor；Merge filter liquor to stand, take supernatant；Supernatant PH is adjusted as neutrality；95% ethyl alcohol of 2 times of volumes is added in, standing takes supernatant；The distilled water of equivalent is added in, filters to obtain clear liquid；15 grams of ephedrine, 1.5 3 grams of nipalgin are added in clear liquid, is filtered again, stores filter liquor.The present invention can be used for caused by treatment flu the diseases such as nasal obstruction is bored, how unfavorable tears are, treat both principal and secondary aspect of disease, therapeutic effect it is good.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition and method more particularly to it is a kind of for treat nasal obstruction Chinese medicine composition and
Method.
Background technology
Flu is also known as the infection of the upper respiratory tract, is the general name for including nasal cavity, pharynx or acute throat inflammation.Flu can because suffering from cold,
Drench with rain, the various the reason for that whole body or respiratory tract local defense function is caused to reduce such as abrupt change of climate, over fatigue and induce, make original
It is present in the upper respiratory tract or is bred rapidly from the virus of external world's intrusion or bacterium, therefore incidence is higher, annual hair of being grown up
2~4 times raw, children's incidence higher, annual 6~8 times, whole year can all fall ill, and winter-spring season is more.
Nasal obstruction, rhinorrhea, sneezing are the conventional symptoms caught a cold.The reason for nasal obstruction be usually virus or bacterium infection after draw
Inflammation disease causes nasal decongestion oedema；Rhinorrhea is then that neutrophil leucocyte causes purulent inflammation or lymph in killing bacterium
For cell when immune response occurs to virus, body occurs what serous inflammation changed and triggered.Due to catching a cold at present not yet
The medicine of special efficacy, and once catch cold and can affect to working, living, therefore, exploitation can be simultaneous with sample
The Chinese medicine composition of the symptoms such as the treatment controlled is had a stuffy nose caused by flu, runny nose, will be to alleviating the cold symptoms of people and to people
Work and life generate active influence.
The content of the invention
In order to solve the shortcoming present in above-mentioned technology, the present invention provides a kind of for treating the Chinese medicine group of nasal obstruction
Close object and method.
In order to solve the above technical problems, the technical solution adopted by the present invention is：A kind of Chinese medicine group for treatment nasal obstruction
Object is closed, is made of the substance of following quality：
Withered and yellow 20-30 grams of a kind of reed mentioned in ancient books, 20-30 grams of Chinese violet,
5-8 grams of licorice, 15 grams of ephedrine,
1.5-3 grams of nipalgin.
Preferably, it is a kind of for treating the Chinese medicine composition of nasal obstruction, it is made of the substance of following quality：Withered and yellow 23 grams of a kind of reed mentioned in ancient books,
28 grams of Chinese violet, 7 grams of licorice, 15 grams of ephedrine, 2 grams of nipalgin.
Preferably, it is a kind of for treating the Chinese medicine composition of nasal obstruction, it is made of the substance of following quality：Withered and yellow 27 grams of a kind of reed mentioned in ancient books,
22 grams of Chinese violet, 6 grams of licorice, 15 grams of ephedrine, 2.5 grams of nipalgin.
A kind of preparation method of Chinese medicine composition for treatment nasal obstruction, concretely comprises the following steps：
First, withered and yellow 20-30 grams of a kind of reed mentioned in ancient books, 20-30 grams of Chinese violet, 5-8 grams of licorice are taken, adds in distilled water 4000ml, it is first military
Fire boils, after be cooked by slow fire one hour, filter, take filter liquor spare；
2nd, into the residue that step 1 filters out again plus distilled water 4000ml, first boil by intense fire, after be cooked by slow fire one hour
Filtering, takes filter liquor spare；
3rd, by twice filter liquor mix place 24 it is small when after, removal precipitation takes supernatant spare；
4th, the supernatant in step 3 is taken, it is 6-7 to adjust PH with sodium acid carbonate；
5th, the supernatant for mixing up PH is taken, according to supernatant：Ethyl alcohol=1：2 volume ratio, adds in 95% ethyl alcohol, then puts
Put 24 it is small when after take supernatant；
6th, the supernatant in step 5 is taken, the distilled water with supernatant equivalent is added in, then filters again, obtain clear and bright liquid
Body；
7th, the clear liquid into step 6 adds in 15 grams of ephedrine, 1.5-3 grams of nipalgin, filters, will filter out again
Hydraulic seal storage, it is spare.
In the present invention, withered and yellow a kind of reed mentioned in ancient books bitter, cold in nature, return lung, stomach, courage, large intestine channel have heat-clearing and damp-drying drug, cool blood tocolysis, removing toxic substances work(
Effect, suitable for caused by retention of damp-heat in the interior jaundice, rush down dysentery, heat gonorrhea, sore carbuncle, damp-warm syndrome, acute fever, cough with lung heat, blood-head bleeding and
Pathopyretic ulcer etc., and using lung heat as the product of first choice.《Medicine origin》Say that it " controls damp and hot in lung, red, hemostasis heap soil or fertilizer over and around the roots of swelling in treatment in hot mesh
Contain, must with medicine ".The clinical practice antibacterial of withered and yellow a kind of reed mentioned in ancient books is not worse than the coptis, and does not develop immunity to drugs.
It is Chinese violet taste bitter, acrid, cold, nontoxic, enter the heart channel of Hang-Shaoyin, Liver Channel, effect is clearing heat and detoxicating, cool blood detumescence, heat-clearing profit
It is wet, it can Yellow River harnessing subcutaneous ulcer, mastitis, red eye, swell pain, venomous snake bite etc..Chinese violet is applied with withered and yellow a kind of reed mentioned in ancient books compatibility, effectiveness is stronger, can be used
Stagnant in dehumidifying of purging heat, detumescence row, treatment coughing with a lot of sputum, hot mesh swell red, the damp and hot diseases such as stagnant.
Licorice be used as medicine it is with a long history, before two thousand years,《Sheng Nong's herbal classic》Just it is classified as the superior of medicine.
Licorice is sweet, and taste is put down, and the thoughts of returning home, lung, spleen, stomach are invigorated the spleen and benefited qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, reconciles all
The effect of medicine, available for weakness of the spleen and the stomach, lassitude hypodynamia, palpitation, coughing with a lot of sputum, gastral cavity abdomen, four limbs contraction, carbuncle swells sore
Poison alleviates drug toxicity, strong.Chinese ephedra is usually accompanied in the wild with licorice, and ephedrine be using natural Herba Ephedrae as
The effects that alkaloid of Raw material processing extraction, there is a loose bronchial smooth muscle, vasoconstriction, excited maincenter, clinical practice is in controlling
Low blood pressure state caused by treating bronchial asthma and a variety of causes also eliminates mucous hyperemia for collunarium.
In inventive formulation, Chinese violet is not only with being all that withered and yellow a kind of reed mentioned in ancient books of clearing heat and detoxicating good medicine is engaged, and also and tonifying spleen
QI invigorating, the licorice of expelling phlegm and arresting coughing are engaged, for treating the diseases such as nasal obstruction caused by flu is bored, how unfavorable tears are, Chinese ephedra
The addition of element can further row be clearing heat and detoxicating, subsides a swelling and goes the benefits of stagnant, and four medicines share, and effect complements each other, and the efficacy of a drug is strengthened.In addition,
A small amount of nipalgin is additionally provided in inventive formulation, nipalgin is all strong typically as antibacterium performance ratio benzoic acid, sorbic acid
Food preservative use, on the one hand can extend quality guarantee period of liquid in this product, on the other hand can also be used as anti-inflammatory
Medicine is for treating the diseases such as cold cough, nasal obstruction, runny nose, and a medicine is mostly used, scientific compatibility.
The present invention is by the synergistic effect of kinds of traditional Chinese medicines, and the nasal obstruction caused available for treatment flu is bored, how unfavorable tears are
Wait diseases, not only good effect, treat both principal and secondary aspect of disease, but also safety coefficient is high, is widely portable to the crowd of various age levels.
Specific embodiment
The present invention will be further described in detail with reference to the specific embodiments.
A kind of Chinese medicine composition for treatment nasal obstruction is made of the substance of following quality：
Withered and yellow 20-30 grams of a kind of reed mentioned in ancient books, 20-30 grams of Chinese violet,
5-8 grams of licorice, 15 grams of ephedrine,
1.5-3 grams of nipalgin.
A kind of preparation method of Chinese medicine composition for treatment nasal obstruction, concretely comprises the following steps：
First, withered and yellow 20-30 grams of a kind of reed mentioned in ancient books, 20-30 grams of Chinese violet, 5-8 grams of licorice are taken, adds in distilled water 4000ml, it is first military
Fire boils, after be cooked by slow fire one hour, filter, take filter liquor spare；
2nd, into the residue that step 1 filters out again plus distilled water 4000ml, first boil by intense fire, after be cooked by slow fire one hour
Filtering, takes filter liquor spare；
3rd, by twice filter liquor mix place 24 it is small when after, removal precipitation takes supernatant spare；
4th, the supernatant in step 3 is taken, it is 6-7 to adjust PH with sodium acid carbonate；
5th, the supernatant for mixing up PH is taken, according to supernatant：Ethyl alcohol=1：2 volume ratio, adds in 95% ethyl alcohol, then puts
Put 24 it is small when after take supernatant；
6th, the supernatant in step 5 is taken, the distilled water with supernatant equivalent is added in, then filters again, obtain clear and bright liquid
Body；
7th, the clear liquid into step 6 adds in 15 grams of ephedrine, 1.5-3 grams of nipalgin, filters, will filter out again
Hydraulic seal storage, it is spare.
Embodiment one,
A kind of Chinese medicine composition for treatment nasal obstruction is made of the substance of following quality：Withered and yellow 20 grams of a kind of reed mentioned in ancient books, Chinese violet
30 grams, 5 grams of licorice, 15 grams of ephedrine, 3 grams of nipalgin.
Its preparation method is：
First, withered and yellow 20 grams of a kind of reed mentioned in ancient books, 30 grams of Chinese violet, 5 grams of licorice are taken, distilled water 4000ml is added in, first boils by intense fire, after
It is cooked by slow fire one hour, filters, take filter liquor spare；
2nd, into the residue that step 1 filters out again plus distilled water 4000ml, first boil by intense fire, after be cooked by slow fire one hour
Filtering, takes filter liquor spare；
3rd, by twice filter liquor mix place 24 it is small when after, removal precipitation takes supernatant spare；
4th, the supernatant in step 3 is taken, it is 6.8 to adjust PH with sodium acid carbonate；
5th, the supernatant for mixing up PH is taken, according to supernatant：Ethyl alcohol=1：2 volume ratio, adds in 95% ethyl alcohol, then puts
Put 24 it is small when after take supernatant；
6th, the supernatant in step 5 is taken, the distilled water with supernatant equivalent is added in, then filters again, obtain clear and bright liquid
Body；
7th, the clear liquid into step 6 adds in 15 grams of ephedrine, 3 grams of nipalgin, filters again, the liquid that will filter out
It is body sealed storage, spare.
Embodiment two,
A kind of Chinese medicine composition for treatment nasal obstruction is made of the substance of following quality：Withered and yellow 30 grams of a kind of reed mentioned in ancient books, Chinese violet
20 grams, 8 grams of licorice, 15 grams of ephedrine, 1.5 grams of nipalgin.
In addition to the dosage difference of each medicinal material, production method is identical with embodiment one.
Embodiment three,
A kind of Chinese medicine composition for treatment nasal obstruction is made of the substance of following quality：Withered and yellow 23 grams of a kind of reed mentioned in ancient books, Chinese violet
28 grams, 7 grams of licorice, 15 grams of ephedrine, 2 grams of nipalgin.
In addition to the dosage difference of each medicinal material, production method is identical with embodiment one.
Example IV,
A kind of Chinese medicine composition for treatment nasal obstruction is made of the substance of following quality：Withered and yellow 27 grams of a kind of reed mentioned in ancient books, Chinese violet
22 grams, 6 grams of licorice, 15 grams of ephedrine, 2.5 grams of nipalgin.
In addition to the dosage difference of each medicinal material, production method is identical with embodiment one.
Embodiment five,
A kind of Chinese medicine composition for treatment nasal obstruction is made of the substance of following quality：Withered and yellow 25 grams of a kind of reed mentioned in ancient books, Chinese violet
25 grams, 6 grams of licorice, 15 grams of ephedrine, 2.5 grams of nipalgin.
In addition to the dosage difference of each medicinal material, production method is identical with embodiment one.
Embodiment six,
A kind of Chinese medicine composition for treatment nasal obstruction is made of the substance of following quality：Withered and yellow 22 grams of a kind of reed mentioned in ancient books, Chinese violet
27 grams, 7 grams of licorice, 15 grams of ephedrine, 2 grams of nipalgin.
In addition to the dosage difference of each medicinal material, production method is identical with embodiment one.
Embodiment seven,
A kind of Chinese medicine composition for treatment nasal obstruction is made of the substance of following quality：Withered and yellow 29 grams of a kind of reed mentioned in ancient books, Chinese violet
21 grams, 6 grams of licorice, 15 grams of ephedrine, 1.5-3 grams of nipalgin.
In addition to the dosage difference of each medicinal material, production method is identical with embodiment one.
Embodiment eight,
A kind of Chinese medicine composition for treatment nasal obstruction is made of the substance of following quality：Withered and yellow 28 grams of a kind of reed mentioned in ancient books, Chinese violet
26 grams, 7 grams of licorice, 15 grams of ephedrine, 1.5 grams of nipalgin.
In addition to the dosage difference of each medicinal material, production method is identical with embodiment one.
The therapeutic effect of the present invention is described further with reference to specific case.
1st, clinical data
200 cold patients are selected, clinical efficacy inspection is carried out using the present invention, wherein woman 135, man 65,
Wherein minimal ages 10,85 years old maximum, the course of disease was at 1 day~1 month.
2nd, therapy
The Chinese medicine composition prepared in selection example one to eight, per bottled 10ml, collunarium three times a day, each 1-2 drops.
3rd, diagnosis and treatment standard：
Effectively：Symptom disappears substantially.
It is invalid：Symptom does not improve.
4th, therapeutic effect
In 200 patients, effective 188, invalid 12, total effective rate 94%.
Model case one,
Mr. Wang, male, 19 years old.With anemofrigid cold, Symptoms are nasal obstruction, flow clear tears, cough, thin white phlegm.Drop is real
The Chinese medicine composition of example one is applied after 1 day, substantially reduced, flow clear tears the symptom of having a stuffy nose disappears, and cough is eased, substantially without
Phlegm.
Model case two,
Zhang, female, 35 years old.Anemopyretic cold, Symptoms are nasal blockage, flow turbid tears, and cough is low voice speaking, pharyngeal dry, sufferings.
Drop is with the Chinese medicine composition of embodiment two after 2 days, and breath is unobstructed, and the number for flowing turbid tears and cough is substantially reduced, it is pharyngeal no longer
Pain dry is itched.
Model case three,
Chen, man, 46 years old.Common cold, nasal obstruction, nasal mucus by clear retrogradation and turn yellow green.The Chinese medicine of drop embodiment three
After composition 1 day, nasal obstruction symptom mitigates, runny nose number significantly reduces, and body is light.
Model case four,
Wu, man, 37 years old.Seasonal influenza, dry cough, pharyngalgia and rhinorrhea.The Chinese medicine composition of drop example IV 2 days
Afterwards, pharyngalgia disappears, and dry cough and symptom snotty are substantially reduced.
Model case five,
Mr. Li, female, 32 years old.With common cold, symptom is flow clear tears, throat itches, sneezes, drops tears.Drop is implemented
After 1 day, each symptom is eased the Chinese medicine composition of example five, and after after treatment 3 days, each symptom disappears substantially.
Model case six,
Song, female, 67 years old.Seasonal influenza, cough, abundant expectoration, sinus pain.The Chinese medicine composition 3 of drop embodiment six
After it, sinus pain disappears, substantially without cough, without phlegm.
Model case seven,
Zheng, man, 25 years old.Virus flu, dry throat pharynx are itched, cough, trachyphonia.The Chinese medicine composition 1 of drop embodiment seven
After it, sound recovers normal, and after after treatment 2 days, throat is no longer dry to itch, cough symptom disappears.
Model case eight,
Liu, female, 15 years old.Virus flu, tonsillotome inflammation, throat is dry to itch, has a stuffy nose.The Chinese medicine group of drop embodiment eight
Object is closed after 2 days, the dry symptom itched, had a stuffy nose of throat disappears, and tonsillotome recovers normal.
The above embodiment is not limitation of the present invention, and the present invention is also not limited to the example above, this technology neck
The variations, modifications, additions or substitutions that the technical staff in domain is made in the range of technical scheme, also belong to this hair
Bright protection domain.
Claims (4)
1. a kind of Chinese medicine composition for treatment nasal obstruction, it is characterised in that：It is made of the substance of following quality：
Withered and yellow 20-30 grams of a kind of reed mentioned in ancient books, 20-30 grams of Chinese violet,
5-8 grams of licorice, 15 grams of ephedrine,
1.5-3 grams of nipalgin.
2. the Chinese medicine composition according to claim 1 for treatment nasal obstruction, it is characterised in that：By the substance of following quality
It is made：Withered and yellow 23 grams of a kind of reed mentioned in ancient books, 28 grams of Chinese violet, 7 grams of licorice, 15 grams of ephedrine, 2 grams of nipalgin.
3. the Chinese medicine composition according to claim 1 for treatment nasal obstruction, it is characterised in that：By the substance of following quality
It is made：Withered and yellow 27 grams of a kind of reed mentioned in ancient books, 22 grams of Chinese violet, 6 grams of licorice, 15 grams of ephedrine, 2.5 grams of nipalgin.
4. a kind of preparation method of the Chinese medicine composition described in claim 1 for treatment nasal obstruction, it is characterised in that：The system
Preparation Method concretely comprises the following steps：
First, withered and yellow 20-30 grams of a kind of reed mentioned in ancient books, 20-30 grams of Chinese violet, 5-8 grams of licorice are taken, adds in distilled water 4000ml, first intense fire boils
Boiling, after be cooked by slow fire one hour, filter, take filter liquor spare；
2nd, into the residue that step 1 filters out again plus distilled water 4000ml, first boil by intense fire, after be cooked by slow fire one hour mistake
Filter, takes filter liquor spare；
3rd, by twice filter liquor mix place 24 it is small when after, removal precipitation takes supernatant spare；
4th, the supernatant in step 3 is taken, it is 6-7 to adjust PH with sodium acid carbonate；
5th, the supernatant for mixing up PH is taken, according to supernatant：Ethyl alcohol=1：2 volume ratio, adds in 95% ethyl alcohol, then places 24
Supernatant is taken after hour；
6th, the supernatant in step 5 is taken, the distilled water with supernatant equivalent is added in, then filters again, obtain clear liquid；
7th, the clear liquid into step 6 adds in 15 grams of ephedrine, 1.5-3 grams of nipalgin, filters again, the liquid that will filter out
It is body sealed storage, spare.
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010241834A (en) * | 2003-02-19 | 2010-10-28 | Rohto Pharmaceut Co Ltd | Pharmaceutical composition |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010241834A (en) * | 2003-02-19 | 2010-10-28 | Rohto Pharmaceut Co Ltd | Pharmaceutical composition |
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| 特级工匠: "商鼻液", 《搜狗百科》 * |
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Application publication date: 20180605 |