CN108104525A - A kind of blocking " U " font solid pharmaceutical preparation workshop - Google Patents

A kind of blocking " U " font solid pharmaceutical preparation workshop Download PDF

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Publication number
CN108104525A
CN108104525A CN201711345851.XA CN201711345851A CN108104525A CN 108104525 A CN108104525 A CN 108104525A CN 201711345851 A CN201711345851 A CN 201711345851A CN 108104525 A CN108104525 A CN 108104525A
Authority
CN
China
Prior art keywords
unit
workshop
corridor
outer shroud
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201711345851.XA
Other languages
Chinese (zh)
Inventor
徐哲
杨勇
骆富平
郎红坤
张春虹
张媛媛
李红
李锦秀
张垚
张瑞超
高灿
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
China Aviation Planning and Design Institute Group Co Ltd
Original Assignee
China Aviation Planning and Design Institute Group Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by China Aviation Planning and Design Institute Group Co Ltd filed Critical China Aviation Planning and Design Institute Group Co Ltd
Priority to CN201711345851.XA priority Critical patent/CN108104525A/en
Publication of CN108104525A publication Critical patent/CN108104525A/en
Withdrawn legal-status Critical Current

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Classifications

    • EFIXED CONSTRUCTIONS
    • E04BUILDING
    • E04HBUILDINGS OR LIKE STRUCTURES FOR PARTICULAR PURPOSES; SWIMMING OR SPLASH BATHS OR POOLS; MASTS; FENCING; TENTS OR CANOPIES, IN GENERAL
    • E04H5/00Buildings or groups of buildings for industrial or agricultural purposes
    • E04H5/02Buildings or groups of buildings for industrial purposes, e.g. for power-plants or factories

Abstract

The present invention is a kind of blocking " U " font solid pharmaceutical preparation workshop,The workshop is provided with the production unit in outer shroud corridor (12) and outer shroud corridor (12) along inside edge,The passage connected at three inside and outside workshop is provided on outer shroud corridor (12),Respectively material inlet (1),Material outlet (11) and stream of people's entrance (4),Passage and production unit are relatively independent at three,Production unit in outer shroud corridor (12) includes one and weighs to pulverize and sieve unit (2),One grain forming unit (3),One preparations shaping unit (5),One coating layered units (6),One intermediate station (9),One cleaning unit (10),First packaging unit (7) and the second packaging unit (8),The workshop can effectively solve the problems, such as appeal,Reduce design,Construction,Verification,Operation and maintenance cost,Workshop is reduced in the case that design production capacity is constant and builds area,Increase area effective rate of utilization,Improve workshop operation efficiency.

Description

A kind of blocking " U " font solid pharmaceutical preparation workshop
Technical field
The present invention is a kind of blocking " U " font solid pharmaceutical preparation workshop, belongs to building structure technology field.
Background technology
Effective workshop arrangement will make people, equipment and material in workshop spatially realize most rational combination, with It reducings the construction costs, labour cost, operating cost, reduces accident, increase ground free space, increase operation rate, improve Operating condition promotes production development.Arrange unreasonable workshop, project cost during capital construction is high, and construction and installation are inconvenient, and workshop is built Into rear and production and problem of management can be brought, cause the stream of people and logistics disorderly, the problems such as plant maintenance and inconvenient maintenance, while Bury larger security risk.
In traditional solid pharmaceutical preparation workshop layout designs, workshop is arranged according to technological process, respectively produces room Relatively independent, intermediate product, which are kept in, to be scattered among each technique productions room, and personage's inflow entrance is without being distinctly claimed.Each production room Being customized design is required according to owner, there is " L " type, " straight line " type etc., the solid pharmaceutical preparation workshop layout designed Otherness is larger.
In the layout designs of traditional solid pharmaceutical preparation workshop, there are following drawbacks:1st, since personage's inflow entrance is without bright Really requirement, therefore there are different situations such as homonymy, both sides, the room layout of workshop is influenced, it is unfavorable for the people of either inside Total logistics cost has the risk of cross contamination;2nd, the larger customization design of differentiation, will improve design and difficulty of construction, increases Add later stage workshop verification cost;3rd, production room is not concentrated, and is unfavorable for reducing operating cost, dedusting, the construction cost of air draft increase Add;4th, intermediate station discrete type designs, and is unfavorable for efficiently using for area, increases the unnecessary area in workshop.
The content of the invention
The present invention be exactly for the above-mentioned prior art present in deficiency and design that provide a kind of blocking " U " font solid Body preparation workshop, the purpose is to overcome conventional customization design solid pharmaceutical preparation workshop the drawbacks of, take into full account owner For the special requirement in workshop production operation area, a kind of standardization, conveniently blocking, workshop layout are provided, carried High workshop service efficiency reduces Workshop Production risk, reduces workshop project cost and operating cost.
The purpose of the present invention is what is be achieved through the following technical solutions:
This kind of blocking " U " font solid pharmaceutical preparation workshop, it is characterised in that:The workshop is provided with outer along inside edge Production unit in ring corridor (12) and outer shroud corridor (12), visit is played the role of in outer shroud corridor 12, by being used for material transportation And personnel channel.The passage connected at three inside and outside workshop is provided on outer shroud corridor (12), is respectively material inlet (1), material Export (11) and stream of people's entrance (4), passage and production unit are relatively independent at three, the production unit in outer shroud corridor (12) Including one weigh pulverize and sieve unit (2), a grain forming unit (3), a preparations shaping unit (5), one coating Unit (6), an intermediate station (9), a cleaning unit (10), the first packaging unit (7) and the second packaging unit (8), material Entrance (1) and material outlet (11) are located at the same side in outer shroud corridor (12) and adjacent, convenient for material transportation.Personnel's entrance is more Clothing unit (4) is located at the opposite side in outer shroud corridor (12), to reduce the cross contamination risk to come in and go out with material, material inlet (1), adjacent, the left side in workshop that pulverizes and sieves unit (2) position is weighed.
Two layers of workshop is provided with the subsidiary engine of pelletizing forming unit (3), preparations shaping unit (5) and coating layered units (6) Between.
Invention proposes providing a kind of fairly simple, rationally distributed solid to workshop, wherein, workshop is by powder Broken, sieving, granulation, total mixed, tabletting (capsule filling), coating, inner packing, outer packing, cleaning auxiliary, intermediate station, composition of changing one's clothes. It is arranged according to the technological process of production, process concentrated setting.Crush, sieving composition claims with unit, using buffering and either inside every From.Weighing pulverizes and sieves unit concentrated setting dust pelletizing system, negative relative in unit.Granulation, total mixed composition grain forming unit, In two layers of concentrated setting equipment subsidiary engine.Tabletting, capsule, which are filled, forms preparations shaping unit, concentrated setting equipment dedusting, in unit Negative relative.Coating is individually composed unit, in two layers of concentrated setting equipment subsidiary engine.Inner packing, outer packing composition packaging unit, are adopted Use the Automation Bottle Packaging Line.All units are set around intermediate station, nearest apart from intermediate station.Intermediate station uses large space pattern, interior Portion's line management, flexibly produces.The unit that pulverizes and sieves is disposed proximate to packaging unit, and supplementary material entrance, which is arranged on, pulverizes and sieves list At member, product outlet is with supplementary material entrance close to logistics elevator.Production technology each unit surrounds intermediate station into " U " font cloth Office.Workshop periphery sets the visit corridor of annular.Personnel, which change one's clothes, is arranged on the opposite side of material entrance.Personnel's unit of changing one's clothes is adopted The sandwich design for intermediate setting laundry whole clothing of being changed one's clothes with men and women.Using the corridor end of fire escape, dirt outlets are set.
The advantages of technical solution of the present invention, is as follows:
1. the scheme of the solid pharmaceutical preparation workshop design of the present invention, advantage is to employ " U " font layout, intermediate erect-position Among workshop, production room reduces transportation range of the intermediate product in workshop, reduction is turned back, reduced around intermediate station arrangement The cost of drug production.
2. intermediate station concentrated setting of the present invention, improves the effective rate of utilization of intermediate station, each production unit stores area It can mutually borrow, in identical production capacity, reduce floor space, reduce operating cost.
3. the solid pharmaceutical preparation workshop of the present invention is rationally distributed, there is not the place of the stream of people and logistics intersection, the stream of people One side is in, logistics is in opposite side, reduces cross contamination risk, to prevent personnel from bringing pollution, this hair when passing in and out clean area It is bright that a special changing room has also been devised, will change one's clothes with laundry whole clothing combined design, be compared to pervious design, more added with The risk controlled when personnel enter the risk of clean area and clothing transmission of effect.
4. the present invention sets and pulverizes and sieves unit, grain forming unit, preparations shaping unit, process is concentrated in each unit, It is unified that air draft, dedusting are set, reduce engineering and operating cost.
5. the all-glass construction security against fire for leading directly to spacious passage is provided in workshop of the present invention in position Outlet while efficient production, has ensured employee's life safety.
6. workshop periphery of the present invention, which is set, visits corridor, the main room that produces externally opens up visit window, shows this workshop spy Color.
Description of the drawings
Fig. 1 is the planar structure schematic diagram in workshop of the present invention
In figure, 1- material inlets;2- weighings pulverize and sieve unit;3- grain forming units;4- changes one's clothes unit;5- preparations Forming unit;6- coating layered units;7- inner packings;8- outer packings;9- intermediate stations;10- cleaning units;11- material outlets;Outside 12- Ring corridor, 13- dirt outlets.
Specific embodiment
Technical solution of the present invention is described further below with reference to drawings and examples:
Referring to shown in attached drawing 1, this kind of blocking " U " font solid pharmaceutical preparation workshop can be realized and produce 10-20 hundred million per year Solid pharmaceutical preparation has production task, it is characterised in that:The workshop is provided with outer shroud corridor (12) and outer shroud corridor along inside edge (12) production unit in, visit is played the role of in outer shroud corridor 12, by being used for material transportation and personnel channel.Outer shroud corridor (12) passage connected at three inside and outside workshop is provided on, is respectively that material inlet (1), material outlet (11) and the stream of people come in and go out Mouthful (4), passage and production unit are relatively independent at three, and the production unit in outer shroud corridor (12) pulverizes and sieves including a weighing Unit (2), a grain forming unit (3), a preparations shaping unit (5), a coating layered units (6), an intermediate station (9), a cleaning unit (10), the first packaging unit (7) and the second packaging unit (8), material inlet (1) and material outlet (11) positioned at the same side of outer shroud corridor (12) and adjacent, convenient for material transportation.Personnel's entrance unit (4) of changing one's clothes is located at outer shroud The opposite side in corridor (12), to reduce the cross contamination risk to come in and go out with material, material inlet (1), weighing pulverize and sieve unit (2) position is adjacent, the left side in workshop.
Two layers of workshop is provided with the subsidiary engine of pelletizing forming unit (3), preparations shaping unit (5) and coating layered units (6) Between.
Workshop structure design is described as follows:
1. loop corridor designs
Workshop periphery sets loop corridor, is used for the stream of people, logistics, visit, maintenance of equipment, and visit, repair need not Either inside is entered, avoids having any impact to production operation.
2. production process designs
Workshop, which includes necessary production unit, production link needed for solid pharmaceutical preparation production, to be included:It crushes, sieve, pelletizing, is total Mixed, tabletting (capsule filling), coating, outer packing, clean auxiliary, intermediate station, change one's clothes at inner packing;
3. production process flow direction design
Workshop of the present invention, workshop are laid out in " U " font, and material entry and exit are in same direction, material After being entered by material inlet, flowed in workshop in " U " font, workshop is finally gone out by material outlet.Material is in workshop in single To flowing, nothing is turned back.
4. material entrance design
Material inlet port is adjacent but misaligned with material product outlet.Material inlet is gone out using outer clear, buffer mode, material Mouth is disposed proximate to using automatic packaging line pattern, material outlet with material inlet, and nearest with shop logistics traffic box.
5. intermediate station designs
Workshop is centered on intermediate station, and function room is around layout.Intermediate station is arranged on workshop center, remaining institute There is unit to be arranged around intermediate station, each unit is nearest with intermediate station.
6. unit of changing one's clothes designs
Workshop of the present invention, stream of people's entrance are designed with stream inlet point both sides, and unit of changing one's clothes is using folder Heart pattern, laundry whole clothing are arranged on men and women and change one's clothes centre, and pass-through box is utilized to transfer clothes, reduces pollution risk.
7. weighing unit designs
The present invention is weighed, crushed, sieving process centralized arrangement.Weighing, crushing, sieving process are all burden process, and raw During production, a large amount of dust generation is had, it is relatively independent with workshop with its air current composition of front and rear cushioning control by centralized arrangement. It is adjacent between weighing unit and outer packing and adjacent with Logistics Transportation box.
8. grain forming unit designs
Present invention granulation, always mixed process is all particle preparatory process, and concentrated setting forms grain forming unit.Equipment is auxiliary Machine is arranged on workshop last layer.
9. preparations shaping unit designs
Tabletting of the present invention, capsule filling work procedure are all solid pharmaceutical preparation molding procedure, and concentrated setting forms preparations shaping list Member, concentrated setting dust pelletizing system.
10. aided process
Between present invention cleaning, it is temporary between be all aided process, be disposed adjacent.Using automatic charging basket cleaning machine will clean between with Connect and set between temporary, between cleaning and it is temporary between concentrated setting room exhaust system.

Claims (2)

1. a kind of blocking " U " font solid pharmaceutical preparation workshop, it is characterised in that:The workshop is provided with outer shroud along inside edge Production unit in corridor (12) and outer shroud corridor (12) is provided on outer shroud corridor (12) and leading to inside and outside workshop is connected at three Road is respectively material inlet (1), material outlet (11) and stream of people's entrance (4), and passage is opposite with production unit only at three Vertical, the production unit in outer shroud corridor (12) includes one and weighs to pulverize and sieve unit (2), grain forming unit (3), one A preparations shaping unit (5), a coating layered units (6), an intermediate station (9), cleaning unit (10), first packaging unit (7) and the second packaging unit (8), material inlet (1) and material outlet (11) are located at the same side in outer shroud corridor (12) and adjacent, Personnel's entrance unit (4) of changing one's clothes is located at the opposite side in outer shroud corridor (12), and material inlet (1), weighing pulverize and sieve unit (2) Position is adjacent, the left side in workshop.
2. blocking " U " font solid pharmaceutical preparation workshop according to claim 1, it is characterised in that:Two layers of workshop is set It is equipped between the subsidiary engine of pelletizing forming unit (3), preparations shaping unit (5) and coating layered units (6).
CN201711345851.XA 2017-12-14 2017-12-14 A kind of blocking " U " font solid pharmaceutical preparation workshop Withdrawn CN108104525A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711345851.XA CN108104525A (en) 2017-12-14 2017-12-14 A kind of blocking " U " font solid pharmaceutical preparation workshop

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711345851.XA CN108104525A (en) 2017-12-14 2017-12-14 A kind of blocking " U " font solid pharmaceutical preparation workshop

Publications (1)

Publication Number Publication Date
CN108104525A true CN108104525A (en) 2018-06-01

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Country Status (1)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110056217A (en) * 2019-04-09 2019-07-26 江中药业股份有限公司 A kind of double-U-shaped solid orally ingestible pharmacy plant designing of solid

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102828631A (en) * 2012-09-21 2012-12-19 吉林化工学院 Design plan of polypeptide freeze-dried powder injection workshops
CN203417748U (en) * 2013-04-11 2014-02-05 中冶沈勘秦皇岛工程技术有限公司 Separation ship for beach placer
CN206381391U (en) * 2016-08-29 2017-08-08 四川省瑞康制药有限公司 A kind of medical solid pharmaceutical preparation workshop
CN107288380A (en) * 2016-03-31 2017-10-24 正大天晴药业集团股份有限公司 A kind of production plot structure of pharmaceutical workshop

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102828631A (en) * 2012-09-21 2012-12-19 吉林化工学院 Design plan of polypeptide freeze-dried powder injection workshops
CN203417748U (en) * 2013-04-11 2014-02-05 中冶沈勘秦皇岛工程技术有限公司 Separation ship for beach placer
CN107288380A (en) * 2016-03-31 2017-10-24 正大天晴药业集团股份有限公司 A kind of production plot structure of pharmaceutical workshop
CN206381391U (en) * 2016-08-29 2017-08-08 四川省瑞康制药有限公司 A kind of medical solid pharmaceutical preparation workshop

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110056217A (en) * 2019-04-09 2019-07-26 江中药业股份有限公司 A kind of double-U-shaped solid orally ingestible pharmacy plant designing of solid

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Application publication date: 20180601

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