CN1081025C - Macule-removing skin-whitening cosmetics containing hydroquinone monopropionate fat and alpha-hydroxy acid - Google Patents
Macule-removing skin-whitening cosmetics containing hydroquinone monopropionate fat and alpha-hydroxy acid Download PDFInfo
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- CN1081025C CN1081025C CN 98126239 CN98126239A CN1081025C CN 1081025 C CN1081025 C CN 1081025C CN 98126239 CN98126239 CN 98126239 CN 98126239 A CN98126239 A CN 98126239A CN 1081025 C CN1081025 C CN 1081025C
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Abstract
The present invention relates to speckle-removing skin-whitening cosmetics containing hydroquinone monopropionate fat and alpha-hydroxy acid. Primarily, the alpha-hydroxy acid with functions of wrinkle resistance, skin repair promotion and skin whitening, anti-oxidants (vitamin C and vitamin E) and skin nutrient amino acid are added to the hydroquinone monopropionate fat which comprises speckle-removing active components. Other adjuvants (substrate, emulsifiers, penetrating agents, preservatives, spices, water, etc.) are matched, and a cream body with stable property is prepared by a conventional emulsification method. The cosmetics have the functions of stable property, difficult oxidation and discoloration for long-term storage, obvious speckle-removing skin-whitening effect, wrinkle resistance, etc.
Description
The present invention relates to the dispelling speckles and whitening face cosmetics, especially a kind of dispelling speckles and whitening face cosmetics that contain hydroquinone mono-propionate and 'alpha '-hydroxy acids
The various types of pigment obstacles of skin mainly are the effects owing to tryrosinase, tyrosine metabolism disorder in the body, and the pigment anomaly deposition causes senile plaque, brown patch, freckle etc.Will stop the formation of these brown patch artificially, mainly be the activity of restraint of tyrosinase.Known synthetic hydroquinone derivatives--hydroquinone mono-propionate has this kind function, has that zest is little, safety good, is easy to be widely used gradually by characteristics such as skin absorbs.But after making cosmetics paste, hydroquinone mono-propionate character instability, easily oxidation and variable color, thus directly influenced the exterior quality and the speckle dispelling curative effect of cosmetics.Traditional in the past solution is to add relatively large low price sulfate (as sodium sulfite, sodium pyrosulfite) as oxidation retarder, but this type of material has zest to skin, and life-time service can produce infringement to skin.
Know that one of melanic excretion pathway is to discharge through skin the sixth of the twelve Earthly Branches, promptly melanin is transferred in the keratin, with the epidermal growth horny layer of dividing a word with a hyphen at the end of a line, comes off with the horny layer metabolism at last.'alpha '-hydroxy acids has comes off dead Skin Cell, thereby promotes skin repair, and delay skin aging reduces characteristics such as mottle.
The object of the invention is, a kind of dispelling speckles and whitening face cosmetics that contain hydroquinone mono-propionate and 'alpha '-hydroxy acids are provided, mainly be in containing speckle dispelling active constituent hydroquinone mono-propionate, add have crease-resistant, promote skin repair, the 'alpha '-hydroxy acids that brightens, and antioxidant vitamin C and vitamin E and skin-nourishing agent aminoacid, be equipped with other adjuvant (as substrate, emulsifying agent, penetrating agent, antiseptic, spice, water etc.) again, adopt conventional emulsification method to make the mastic of stable in properties.
Principle of the present invention is the adding of 'alpha '-hydroxy acids in the cosmetics, and may command mastic pH value is in the 4-6.5 scope, and with this understanding, the chemical property of hydroquinone mono-propionate is stable, is difficult for oxidized.And 'alpha '-hydroxy acids have the activation Skin Cell, crease-resistant, brighten isoreactivity, with the composite synergism of hydroquinone mono-propionate with dispelling speckles and whitening face.Vitamin C and vitamin E promptly can be used as antioxidant in this cosmetic formulations, suppress the oxidation of hydroquinone mono-propionate, again with prescription in the same effect of aminoacid that adds with nutrition skin, vitamin C is the effect of Pear Power skin also.
A kind of dispelling speckles and whitening face cosmetics that contain hydroquinone mono-propionate and 'alpha '-hydroxy acids of the present invention, the consumption of hydroquinone mono-propionate is 0.5-20 part in cosmetics, 'alpha '-hydroxy acids is lactic acid or hydroxyacetic acid or malic acid or citric acid or tartaric acid or its mixture, its consumption is 1-20 part, vitamin is a vitamin C, vitamin E, its consumption is 0-2 part, aminoacid is cystine or glycine, its consumption is 0-1 part, be equipped with other cosmetics adjuvant again (as substrate, emulsifying agent, penetrating agent, antiseptic, spice, water etc.), adopt conventional emulsification method preparation, pH value is that 4-6.5 gets final product.
The present invention has carried out embrocating test to the patient who suffers from brown patch, freckle: wipe examination with the mastic that contains 3.6% (weight ratio) hydroquinone mono-propionate and 8.7% (weight ratio) 'alpha '-hydroxy acids, use its result of person such as following table more than two months continuously:
Embodiment 1 (is unit with the weight portion)
At first with 4 parts in vaseline, 2 parts of glyceryl monostearates, 1.5 parts of hexadecanol, 3.7 parts of stearic acid, 4.2 parts of liquid paraffin, 2.3 parts of Oleum Ricini, 2.6 parts of anhydrous sorbitol monopalmitates, 0.5 part of hydroquinone mono-propionate, 0.7 part of vitamin E and 1.5 parts of mixing of antiseptic, spice, penetrating agent commonly used, 70 ℃ down with the water of 2.5 parts of hydroxyacetic acid, 12 parts of lactic acid, 4 parts in tartaric acid, 10 parts of glycerol, 0.5 part of vitamin C, 1 part of glycine, water surplus, and, adopt conventional method emulsifying, cooling to get final product again with potassium hydroxide aqueous solution accent PH 4.
Embodiment 2 (is unit with the weight portion)
At first with 12 parts of hard paraffins, 5 parts in vaseline, 6 parts of hydrogenated lanolins, 19 parts of squalanes, 2 parts in Cera Flava, 2.5 parts of glyceryl monostearates, 1.2 parts of Tween-81s, 5 parts of hydroquinone mono-propionates and 1.5 parts of mixing of antiseptic, spice, penetrating agent commonly used, 70 ℃ down with the water of 2 parts of lactic acid, 9.5 parts of malic acids, 1 part in tartaric acid, 1 part of vitamin C, 0.02 part of cystine, water surplus, and, adopt conventional method emulsifying, cooling to get final product again with potassium hydroxide aqueous solution accent PH 5.5.
Embodiment 3 (is unit with the weight portion)
At first with 4 parts of octadecanol, 5.5 parts of Oleum Ricini, 10 parts of glyceryl monostearates, 2 parts of polyoxyethylene 20 sorbitan monolaurates, 10 parts of hydroquinone mono-propionates and 1.5 parts of mixing of antiseptic, spice, penetrating agent commonly used, 70 ℃ down with the water of 1 part of hydroxyacetic acid, 1 part of vitamin C, water surplus, and, adopt conventional method emulsifying, cooling to get final product again with potassium hydroxide aqueous solution accent PH 6.0.
Embodiment 4 (is unit with the weight portion)
At first with 5 parts of i-octadecanols, 2 parts of safflower oils, 20 parts of glyceryl monostearates, 6 parts of hydroquinone mono-propionates, 2.8 parts of sorbitan monooleates, 0.5 part of vitamin E and 1.5 parts of mixing of antiseptic, spice, penetrating agent commonly used, 70 ℃ down with the water of 0.5 part of hydroxyacetic acid, 2 parts of lactic acid, 2 parts of citric acids, water surplus, and, adopt conventional method emulsifying, cooling to get final product again with potassium hydroxide aqueous solution accent PH 6.5.
Claims (2)
1, a kind of dispelling speckles and whitening face cosmetics that contain hydroquinone mono-propionate and 'alpha '-hydroxy acids, it is characterized in that, the consumption of hydroquinone mono-propionate is that 0.5-20 part, 'alpha '-hydroxy acids are lactic acid or hydroxyacetic acid or malic acid or citric acid or tartaric acid or its mixture in cosmetics, its consumption is 1-20 part, vitamin is vitamin C, vitamin E, its consumption is 0-2 part, aminoacid is cystine or glycine, its consumption is 0-1 part, be equipped with other cosmetics adjuvant again, adopt conventional emulsification method preparation, pH value is that 4-6.5 gets final product.
2, a kind of dispelling speckles and whitening face cosmetics that contain hydroquinone mono-propionate and 'alpha '-hydroxy acids according to claim 1 is characterized in that described adjuvant is substrate, emulsifying agent, penetrating agent, antiseptic, spice, water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 98126239 CN1081025C (en) | 1998-12-17 | 1998-12-17 | Macule-removing skin-whitening cosmetics containing hydroquinone monopropionate fat and alpha-hydroxy acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 98126239 CN1081025C (en) | 1998-12-17 | 1998-12-17 | Macule-removing skin-whitening cosmetics containing hydroquinone monopropionate fat and alpha-hydroxy acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1256912A CN1256912A (en) | 2000-06-21 |
| CN1081025C true CN1081025C (en) | 2002-03-20 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 98126239 Expired - Fee Related CN1081025C (en) | 1998-12-17 | 1998-12-17 | Macule-removing skin-whitening cosmetics containing hydroquinone monopropionate fat and alpha-hydroxy acid |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1081025C (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY155276A (en) * | 2007-04-12 | 2015-09-30 | Malaysian Palm Oil Board | Botanical extracts from oil palm vegetation liquor cosmeceutical applications |
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1998
- 1998-12-17 CN CN 98126239 patent/CN1081025C/en not_active Expired - Fee Related
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| Publication number | Publication date |
|---|---|
| CN1256912A (en) | 2000-06-21 |
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