CN108096498A - 宁肾汤及其制备方法 - Google Patents

宁肾汤及其制备方法 Download PDF

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CN108096498A
CN108096498A CN201810109361.8A CN201810109361A CN108096498A CN 108096498 A CN108096498 A CN 108096498A CN 201810109361 A CN201810109361 A CN 201810109361A CN 108096498 A CN108096498 A CN 108096498A
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刘楠楠
李子龙
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Diabetes Hospital Of Fuxin City
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Abstract

本发明属于医疗行业中的中药汤剂，特别涉及一种治疗肾脏病的宁肾汤及其制备方法。宁肾汤包括下列重量份的中药：水61份，鸡血藤4份，枸杞子4份，夏枯草3份，太子参4份，狗脊6份，补骨脂3份，红花3份，鳖甲3份，泽兰3份，薏苡仁3份，桑椹子3份。宁肾汤的制备方法如下：按重量份取中药鸡血藤4份，枸杞子4份，夏枯草3份，太子参4份，狗脊6份，补骨脂3份，红花3份，鳖甲3份，泽兰3份，薏苡仁3份，桑椹子3份，把上述中药清洗干净后，加水浸泡30分钟，放入瓷质或不锈钢锅中，加入61份的水用大火煮沸后改用小火煎煮40分钟浓缩，加入适量的防腐剂，在清洁避菌的环境中装于无菌洁净干燥容器中，装袋封好，放入冰箱冷藏保管。

Description

宁肾汤及其制备方法
技术领域
本发明属于医疗行业中的中药汤剂，特别涉及一种治疗肾脏病的宁肾汤及其制备方法。
背景技术
目前，慢性肾脏病是一种严重危害人类健康和生命的疾病，发病率高达10.8%，导致肾功能衰竭比例更高，给家庭和社会带来巨大负担。治疗肾脏病的药物品种较多，西药治疗存在效果不理想，价格昂贵与国情不符，而且用药有一定的局限性及明显的副作用。国内中成药品种繁多，市场混乱，价格不菲，疗效不确切。其他静脉用药有临床效果不持续，药物性价比不高等现实问题。
发明内容
本发明的目的在于克服上述不足，提供一种疗效好、副作用小、服用方便的治疗肾脏病的药物宁肾汤及其制备方法。
本发明治疗肾脏病的宁肾汤及其制备方法采用的方案是：宁肾汤包括下列重量份的中药：水61份，鸡血藤4份，枸杞子4份，夏枯草3份，太子参4份，狗脊6份，补骨脂3份，红花3份，鳖甲3份，泽兰3份，薏苡仁3份，桑椹子3份；
鸡血藤，异名：血风藤、血藤、三爷鸡血藤。性味：苦、微甘，温。归经：入肝、肾经。功效：补血、活血、通络。主治月经不调，血虚萎黄，风湿痹痛，麻木瘫痪。
枸杞子，异名：枸杞果。性味：甘，平。归经：入肝、肾经。功效：滋补肝肾，益精明目。主治虚劳精亏，眩晕耳鸣，腰膝酸软，目昏不明，消渴等。
夏枯草，异名：夏枯头、夏枯球、棒槌草、铁色草、大头花、铁钱夏枯、麦穗夏枯草。性味：辛、苦，寒。归经：入肝、胆经。功效：泻火明目，散结消肿。主治目赤肿痛，头痛眩晕，目珠夜痛， 瘿瘤，乳痈肿痛。
太子参，异名：孩儿参、童参。性味：甘、微苦，平。归经：入脾、肺经。功效：补气健脾，生津润肺。主治肺脾气阴两虚证，倦怠自汗，饮食减少，口干少津，不宜温补者。
狗脊，异名：金毛狗、金毛狗脊、金狗脊、金丝毛。性味：苦、甘，温。归经：入肝、肾经。功效：祛风湿，补肝肾，强腰膝。主治肾虚腰痛脊强，足膝软弱无力，遗尿等。
补骨脂，异名：故子、破故子、破故纸、胡韭子、婆固脂、黑故子。性味：苦、辛，温。归经：入肾、脾经。功效：补肾助阳，固精缩尿，温脾止泻，纳气平喘。主治肾虚阳痿，腰膝冷痛，肾虚遗精遗尿，尿频，脾肾阳虚，五更泄泻，肾不纳气，虚寒喘咳。
红花，异名：草红花、刺红花、金红花、杜红华、红蓝花、黄蓝花、怀红花。性味：辛，温。归经：入心、肝经。功效：活血通经，祛瘀止痛。主治血瘀经闭，瘀滞腹痛，症瘕积聚，胸痹心痛，血瘀腹痛，胁痛等。
鳖甲，异名：团鱼甲、水鱼壳、团鱼壳、鳖盖、脚鱼壳、上甲、王八盖子。性味：甘、咸，寒。归经：入肝、肾经。功效：滋阴潜阳，退热除蒸，软坚散结。主治肝肾阴虚，症瘕积聚。
泽兰，异名：毛叶地瓜苗。性味：苦、辛，微温。归经：入肝脾经。功效：活血通经，祛瘀消痈，利水消肿，主治血瘀经闭，瘀滞腹痛，瘀肿疼痛，水肿腹水。
薏苡仁，异名：薏仁、薏米、苡仁。性味：甘、淡，凉。归经：入脾、胃、肺经。功效：利水消肿，渗湿，健脾，除痹，清热排脓。主治水肿，小便不利，脚气，脾虚泄泻，湿痹拘挛等。
桑椹，异名：桑甚子、桑实、桑果。性味：甘、酸，寒。归经：入肝、肾经。功效：滋阴补血，生津润燥。主治肝肾阴虚，津伤口渴、消渴肠燥便秘等症。
宁肾汤的制备方法如下：按重量份取中药鸡血藤4份，枸杞子4份，夏枯草3份，太子参4份，狗脊6份，补骨脂3份，红花3份，鳖甲3份，泽兰3份，薏苡仁3份，桑椹子3份，把上述中药清洗干净后，加水浸泡30分钟，放入瓷质或不锈钢锅中，加入61份的水用大火煮沸后改用小火煎煮40分钟浓缩，加入适量的防腐剂，在清洁避菌的环境中装于无菌洁净干燥容器中，装袋封好，放入冰箱冷藏保管。
本发明的有益效果是：宁肾汤减轻临床症状，改善肾脏微循环的病理生理状态，进一步减轻血尿、蛋白尿及保护血管内支细胞，延缓慢性肾功能疾病的进展。此药可治疗糖尿病肾病、肾病综合症、慢性肾功能衰竭，属纯中药制剂，疗效好，价格合理，口服安全，使患者易于接受，减少中草药的毒副反应。
具体实施方式
以下结合典型病例对本发明进行具体说明。
实施例：取补骨脂30g、鳖甲30g、泽兰30g、狗脊60g、枸杞子40g、夏枯草30g、薏苡仁30g、太子参40g、鸡血藤40g、桑椹子30g、红花30g，把上述中药材洗净后，加水浸泡30分钟，放入不锈钢煎药锅中，加入610ml水，选用大火煮沸后改用文火煎煮40分钟浓缩，加入适宜的防腐剂，在清洁避菌的环境中灌装与无菌的洁净干燥容器中，装袋封好，放入冰箱冷藏保管。
宁肾汤的使用方法：每日3次温服，即早饭前，午、晚饭后，饭与药间隔半小时为宜。每次口服100ml，20天一疗程。
以下提供6个典型病例。
病例一：赵某某，男，67岁，2型糖尿病病史8年，化验检查尿微量蛋白78.9mg/l，诊断为糖尿病肾病早期，服用宁肾汤治疗1个月，尿微量蛋白恢复正常。
病例二：孙玉英，女，70岁，慢性肾炎，慢性肾功能衰竭，血肌酐216.2umol/l，尿素氮14.7mmol/l，24h尿蛋白定量2.49g，服用宁肾汤治疗10个月，各项指标改善，复查血肌酐166.7umol/l，尿素氮10.7mmol/l，24小时尿蛋白定量1.25g。
病例三：张彦福，男，62岁，慢性肾功能衰竭病史3年，2型糖尿病病史2年，血肌酐226.4umol/l，尿素氮12.4mmol/l，尿微量蛋白201.4mmg/l，服用宁肾汤治疗2个月，各项指标改善，血肌酐157.34umol/l，尿素氮8。10mmol/l，尿微量蛋白76.2mg/dl。
病例四：李艳梅，女，60岁，2型糖尿病病史10年，糖尿病肾病2年余，心脏支架术后，尿微量蛋白237mg/l，服用宁肾汤治疗2个月，尿微量蛋白89.7mg/dl。
病例五：刘昊，男，22岁，慢性肾炎病史2年，24小时尿蛋白定量3.276g，服用宁肾汤治疗1个月，2小时尿蛋白定量0.2g。
病例六：张丽杰，女，54岁，确诊糖尿病肾病三期，尿微量蛋白147.7mmg/l，服用宁肾汤治疗2个月，尿微量蛋白降低到58.2mmg/l。

Claims (2)

1.一种宁肾汤包括下列重量份的中药：水61份，鸡血藤4份，枸杞子4份，夏枯草3份，太子参4份，狗脊6份，补骨脂3份，红花3份，鳖甲3份，泽兰3份，薏苡仁3份，桑椹子3份。
2.根据权利要求1所述的宁肾汤，其特征在于宁肾汤的制备方法如下：按重量份取中药鸡血藤4份，枸杞子4份，夏枯草3份，太子参4份，狗脊6份，补骨脂3份，红花3份，鳖甲3份，泽兰3份，薏苡仁3份，桑椹子3份，把上述中药清洗干净后，加水浸泡30分钟，放入瓷质或不锈钢锅中，加入61份的水用大火煮沸后改用小火煎煮40分钟浓缩，加入适量的防腐剂，在清洁避菌的环境中装于无菌洁净干燥容器中，装袋封好，放入冰箱冷藏保管。
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Citations (2)

* Cited by examiner, † Cited by third party
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CN105878837A (zh) * 2016-05-30 2016-08-24 阜新市糖尿病医院 治疗肾病的中药
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