CN108096040B

CN108096040B - Whitening stable slurry, tooth whitening film and preparation method thereof

Info

Publication number: CN108096040B
Application number: CN201810091950.8A
Authority: CN
Inventors: 黄睿祥
Original assignee: Individual
Current assignee: Individual
Priority date: 2018-01-30
Filing date: 2018-01-30
Publication date: 2024-01-30
Anticipated expiration: 2038-01-30
Also published as: CN108096040A

Abstract

The invention relates to whitening stable slurry, tooth whitening adhesive film and a preparation method thereof, wherein the whitening stable slurry is mainly prepared from the following raw materials in percentage by mass: 30 to 70 percent of water, 25 to 65 percent of penetration enhancer, 0.5 to 8 percent of polyvinyl alcohol, 0.5 to 4 percent of carbon fiber, 0.5 to 4 percent of hydrogenated dimer (linolen) carbonate-dimethyl carbonate copolymer, 0.5 to 3 percent of polydimethylsiloxane crosslinked polymer and 0.2 to 2 percent of pH buffer. The tooth whitening film disclosed by the invention is simple and convenient to use, has a longer shelf life, can ensure a good tooth whitening care effect in a longer time, and has lower tooth whitening care cost. When in use, the back lining layer and the whitening layer can be separated from the stripping layer and the whitening stabilizing layer, then the whitening layer is stuck on the surface of teeth to enable the whitening layer to be in contact with the teeth, and the back lining layer is torn off the teeth after a certain time.

Description

Whitening stable slurry, tooth whitening film and preparation method thereof

Technical Field

The invention relates to the field of tooth protection, in particular to whitening stable slurry, a tooth whitening film and a preparation method thereof.

Background

In recent years, people pay more attention to tooth whitening care, and a plurality of related products such as whitening care toothpaste, special bleaching liquid for dentistry, mouthwash, tooth whitening gel, tooth whitening film and the like are correspondingly produced, wherein the tooth whitening film is simple, convenient and attractive to use and is accepted by more and more consumers. However, the tooth whitening adhesive film using the polymer gel as the matrix in the market at present has a short shelf life under normal temperature, and after a period of time, the problems of gel dispersion, dissolution, smell change and the like often occur, so that the tooth whitening adhesive film is deteriorated and the effect is greatly reduced.

Disclosure of Invention

Based on this, it is necessary to provide a whitening stabilizing slurry that can extend the shelf life of tooth whitening patches.

The whitening stable slurry is mainly prepared from the following raw materials in percentage by mass: 30 to 70 percent of water, 25 to 65 percent of penetration enhancer, 0.5 to 8 percent of polyvinyl alcohol, 0.5 to 4 percent of carbon fiber, 0.5 to 4 percent of hydrogenated dimer (linolen) carbonate-dimethyl carbonate copolymer, 0.5 to 3 percent of polydimethylsiloxane crosslinked polymer and 0.2 to 2 percent of pH buffer.

In one embodiment, the material is mainly prepared from the following raw materials in percentage by mass: 45-55% of water, 35-45% of penetration enhancer, 3-6% of polyvinyl alcohol, 1-3% of carbon fiber, 1-2% of hydrogenated dimer (linolenate) carbonate-dimethyl carbonate copolymer, 1-2% of polydimethylsiloxane crosslinked polymer and 0.6-1.6% of pH buffer.

In one embodiment, the whitening stabilizing slurry has a pH of from 4 to 9.

In one embodiment, the whitening stabilization slurry has a viscosity of 5000 mPas to 15000 mPas.

In one embodiment, the permeation enhancer is ethanol and the pH buffer is sodium dihydrogen phosphate and sodium phosphate.

The invention also provides a tooth whitening film, which comprises a stripping layer, a whitening stabilizing layer, a whitening layer and a backing layer which are sequentially laminated, wherein the whitening stabilizing layer is formed by the whitening stabilizing slurry.

In one embodiment, the whitening layer is prepared from the following raw materials: a thickener, a humectant, a whitening agent, a flavoring agent, a chelating agent, a pH regulator, a flavoring agent and water.

In one embodiment, the thickener is one or more of magnesium aluminum silicate, chitin, sodium lignin sulfonate, VP-hexadecene copolymer, lignin fiber, carbon fiber, polyvinylpyrrolidone, sodium cellulose, polyvinyl alcohol, ethylcellulose, carbomer, pectin, xanthan gum, and gelatin.

In one embodiment, the whitening agent is one or more of hydrogen peroxide, peracetic acid, carbamide peroxide, sodium bicarbonate, sodium carbonate, chlorine dioxide, linoleic acid, tartaric acid, silica, charcoal, and diatomaceous earth.

The invention also provides a preparation method of the tooth whitening film, which comprises the following steps: mixing and stirring water, a penetration enhancer, a polydimethylsiloxane crosslinked polymer and a pH buffer agent uniformly, heating to 70-80 ℃, adding polyvinyl alcohol, carbon fiber and hydrogenated dimer (linolic acid) carbonate-dimethyl carbonate copolymer, and stirring uniformly to obtain whitening stable slurry, cooling the whitening stable slurry, coating the whitening stable slurry on the stripping layer to form the whitening stable layer, and sequentially forming the whitening layer and the backing layer on the whitening stable layer to obtain the tooth whitening adhesive film.

The whitening stabilizing slurry can be used for forming a whitening stabilizing layer between a stripping layer and a whitening layer of a tooth whitening film, the hydrogenated dimer (linolenate) -dimethyl carbonate copolymer, the polyvinyl alcohol and the carbon fiber in the whitening stabilizing layer are helpful for enabling the whitening layer to be tightly attached, reducing air remained during production between the whitening layer and the stripping layer, simultaneously, the polydimethylsiloxane crosslinked polymer can effectively improve the compatibility of the whitening stabilizing layer and the whitening layer, the penetration enhancer can further improve the release of active ingredients in the whitening layer during product use, the pH buffering agent is helpful for improving the stability of the whitening stabilizing layer, the stability of physicochemical indexes of the whitening layer can be improved through the synergistic effect of the aspects, and the shelf life of the tooth whitening film is prolonged, so that the tooth whitening film can maintain good tooth whitening care effect in a longer time. When in use, the back lining layer and the whitening layer can be separated from the stripping layer and the whitening stabilizing layer, then the whitening layer is stuck on the surface of teeth to enable the whitening layer to be in contact with the teeth, and the back lining layer is torn off the teeth after a certain time. The tooth whitening film disclosed by the invention is simple and convenient to use, has a longer shelf life, can ensure a good tooth whitening care effect in a longer time, and has lower tooth whitening care cost.

Drawings

Fig. 1 is a schematic structural diagram of a tooth whitening film according to an embodiment;

fig. 2 is a top view of the tooth whitening strip shown in fig. 1.

Detailed Description

The present invention will be described more fully hereinafter in order to facilitate an understanding of the present invention, and preferred embodiments of the present invention are set forth. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.

The whitening stable slurry of the embodiment of the invention is mainly prepared from the following raw materials in percentage by mass: 30 to 70 percent of water, 25 to 65 percent of penetration enhancer, 0.5 to 8 percent of polyvinyl alcohol, 0.5 to 4 percent of carbon fiber, 0.5 to 4 percent of hydrogenated dimer (linolen) carbonate-dimethyl carbonate copolymer, 0.5 to 3 percent of polydimethylsiloxane crosslinked polymer and 0.2 to 2 percent of pH buffer.

The whitening stabilizing slurry of the embodiment can be used for forming a whitening stabilizing layer between a stripping layer and a whitening layer of a tooth whitening film, the hydrogenated dimer (linolenate) -dimethyl carbonate copolymer, the polyvinyl alcohol and the carbon fiber in the whitening stabilizing layer are helpful for enabling the whitening layer to be tightly attached, reducing air remained during production between the whitening layer and the stripping layer, simultaneously, the polydimethylsiloxane crosslinked polymer can effectively improve the compatibility of the whitening stabilizing layer and the whitening layer, the penetration enhancer can further improve the release of active ingredients in the whitening layer during product use, the pH buffering agent is helpful for improving the stability of the whitening stabilizing layer, the stability of physicochemical indexes of the whitening layer can be improved through the synergistic effect of the aspects, and the shelf life of the tooth whitening film is prolonged, so that the tooth whitening film can maintain good tooth whitening nursing effect in a longer time. When in use, the back lining layer and the whitening layer can be separated from the stripping layer and the whitening stabilizing layer, then the whitening layer is stuck on the surface of teeth to enable the whitening layer to be in contact with the teeth, and the back lining layer is torn off the teeth after a certain time.

In one embodiment, the whitening stable slurry is prepared mainly from the following raw materials in percentage by mass: 45-55% of water, 35-45% of penetration enhancer, 3-6% of polyvinyl alcohol, 1-3% of carbon fiber, 1-2% of hydrogenated dimer (linolenate) carbonate-dimethyl carbonate copolymer, 1-2% of polydimethylsiloxane crosslinked polymer and 0.6-1.6% of pH buffer.

In one embodiment, the pH value of the whitening stable slurry is 4-9, and the pH value can be adjusted by adjusting the addition of the pH buffering agent, so that the whitening stable layer formed by the slurry in the pH range has better stabilizing effect, and the quality guarantee period of the product is prolonged.

In one embodiment, the viscosity of the whitening stable slurry is 5000 mPa.s-15000 mPa.s, the viscosity can be changed by adjusting the proportion of the raw materials, and the whitening stable layer formed by the slurry within the viscosity range has better stabilizing effect, and the shelf life of the product can be further prolonged.

Optionally, the penetration enhancer is ethanol, the pH buffering agent is sodium dihydrogen phosphate and sodium phosphate, and the penetration enhancing and pH buffering effects are better.

As shown in fig. 1, the tooth whitening strip film 100 according to an embodiment of the present invention includes a peeling layer 10, a whitening stabilizing layer 20, a whitening layer 30, and a backing layer 40, which are sequentially stacked, and the whitening stabilizing layer 20 is formed of the above-described whitening stabilizing slurry.

The tooth whitening film 100 of the embodiment is provided with the whitening stabilizing layer 20 between the peeling layer 10 and the whitening layer 30, so that the stability of physicochemical indexes of the whitening layer 30 can be improved, and the shelf life of the tooth whitening film 100 can be prolonged, thereby ensuring that the tooth whitening film 100 can maintain a good tooth whitening care effect in a longer time, and the tooth whitening film is simple and convenient to use and has lower tooth whitening care cost.

Optionally, the whitening layer 30 is prepared mainly from the following raw materials: a thickener, a humectant, a whitening agent, a flavoring agent, a chelating agent, a pH regulator, a flavoring agent and water.

Specifically, the thickener is one or more of aluminum magnesium silicate, chitin, sodium lignin sulfonate, VP-hexadecene copolymer, lignin fiber, carbon fiber, polyvinylpyrrolidone, sodium cellulose, polyvinyl alcohol, ethylcellulose, carbomer, pectin, xanthan gum and gelatin. After the materials such as aluminum magnesium silicate, chitin, sodium lignin sulfonate, VP/hexadecene copolymer, lignin fiber and/or carbon fiber are added into the whitening layer 30, the tooth whitening effect is more stable, the effect is more obvious, and the shelf life can be further prolonged.

Optionally, the humectant is glycerin and/or propylene glycol, the flavoring agent is saccharin sodium, xylitol and/or sorbitol, the chelating agent is disodium ethylenediamine tetraacetate and/or sodium citrate, the pH regulator is sodium dihydrogen phosphate, sodium phosphate, malic acid, citric acid, sodium citrate and/or sodium hydroxide, and the flavoring agent is menthol and/or essence.

Specifically, the whitening agent is one or more of hydrogen peroxide, peracetic acid, carbamide peroxide, sodium bicarbonate, sodium carbonate, chlorine dioxide, linoleic acid, fruit acid, silicon dioxide, charcoal and diatomite. When the whitening agent is peroxide such as hydrogen peroxide, zinc peroxide, carbamide peroxide, peracetic acid and the like, the whitening layer 30 can slowly release the peroxide after being closely attached to the tooth surface, so that the effect of whitening teeth and not stimulating the oral cavity as much as possible is achieved; when the whitening agent is non-peroxide such as sodium bicarbonate, sodium carbonate, chlorine dioxide, sodium chlorate, linoleic acid, fruit acid, vitamin C and the like, propylene glycol, ethanol and the like are added into the whitening layer, and the whitening layer 30 can promote the release of the non-peroxide whitening agent after being tightly attached to the tooth surface, so that the effect of whitening teeth is achieved; when the whitening agent is a component having a physical impurity adsorption effect such as silica, carbon powder, diatomaceous earth, etc., the whitening layer 30 is closely adhered to the tooth surface, and then impurities on the tooth surface can be removed by adsorption, thereby achieving a tooth whitening effect.

In one embodiment, the whitening layer 30 is prepared from the following raw materials in mass percent: 50 to 60 percent of water, 25 to 35 percent of glycerol, 3 to 5 percent of sorbitol, 2 to 5 percent of cellulose sodium, 2 to 5 percent of aluminum magnesium silicate, 2 to 5 percent of sodium lignin sulfonate, 1 to 3 percent of VP-hexadecene copolymer, 0.2 to 1 percent of xanthan gum, 3 to 6 percent of hydrogen peroxide, 1 to 3 percent of silicon dioxide, 0.1 to 0.5 percent of disodium ethylenediamine tetraacetate, 0.05 to 0.3 percent of menthol and 0.05 to 0.5 percent of essence.

In one embodiment, the whitening layer 30 is prepared from the following raw materials in mass percent: 40 to 60 percent of water, 25 to 40 percent of glycerol, 3 to 5 percent of sorbitol, 2 to 5 percent of cellulose sodium, 1 to 2 percent of carbomer, 1 to 2 percent of lignin fiber, 0.5 to 2 percent of pectin, 3 to 18 percent of carbamide peroxide, 1 to 5 percent of diatomite, 0.5 to 2 percent of linoleic acid, 0.1 to 0.3 percent of disodium ethylenediamine tetraacetate, 0.1 to 0.5 percent of sodium hydroxide and 0.05 to 0.5 percent of menthol.

In one embodiment, the whitening layer 30 is prepared from the following raw materials in mass percent: 40 to 60 percent of water, 25 to 40 percent of glycerol, 3 to 8 percent of propylene glycol, 1 to 5 percent of ethanol, 2 to 5 percent of cellulose sodium, 1 to 5 percent of VP-hexadecene copolymer, 1 to 3 percent of chitin, 1 to 3 percent of carbon fiber, 0.5 to 5 percent of chlorine dioxide, 0.5 to 5 percent of sodium bicarbonate, 0.5 to 3 percent of kieselguhr, 0.5 to 3 percent of polyvinylpyrrolidone, 0.5 to 3 percent of xylitol, 0.1 to 0.8 percent of sodium phytate, 0.1 to 0.3 percent of disodium edetate and 0.1 to 0.5 percent of menthol.

In one embodiment, the whitening layer 30 has a thickness of 0.05mm to 1.5mm, and adheres to the tooth surface substantially without causing discomfort and reduces oral irritation. In one embodiment, the whitening stabilization layer 20 has a thickness of 0.005mm to 0.01mm.

In one embodiment, the backing layer 40 is a polyolefin film having a thickness of 0.005mm to 0.02mm, which facilitates stable attachment to the tooth surface without affecting oral activity such as normal speech communication of a person.

In one embodiment, the backing layer 40 is rectangular in shape, having a length of 4cm to 8cm and a width of 0.5cm to 2.5cm, to facilitate adhesion to teeth with minimal or no contact to gums.

In one embodiment, as shown in fig. 2, at least one side edge of the backing layer 40 extending in the length direction is provided with at least two notches 401, and the notches 401 are spaced apart. In this way, the backing layer 40 can be conveniently folded along the length direction in the use process, so that a part of the whitening layer 30 can be more easily and accurately attached to one face of the teeth facing the inner side of the oral cavity, and the area ratio of the whitening layer 30 attached to the outer surface (facing the outer side of the oral cavity) and the inner surface (facing the inner side of the oral cavity) of the teeth can also be conveniently adjusted by adjusting the folded part. In this embodiment, the notch 401 is a V-shaped notch.

In one embodiment, the release layer 10 is a plastic sheet having a thickness of 0.05mm to 0.5mm.

In one embodiment, the release layer 10 is rectangular in shape, having a length of 7cm to 10cm and a width of 2cm to 5cm.

In one embodiment, an adhesive layer 50 is further disposed between the backing layer 40 and the whitening layer 30, which is advantageous in improving adhesion between the backing layer 40 and the whitening layer 30, avoiding separation of the backing layer 40 from the whitening layer 30, and facilitating rapid separation of the whitening layer 30 from the release layer 10 when the backing layer 40 is peeled off.

In one embodiment, the surface of the backing layer 40 is provided with embossments. In this way, the aesthetics of the product can be improved, while also facilitating quick identification of the backing layer 40 and the release layer 10.

In one embodiment, the number of the whitening layers 30 is plural, and the plural whitening layers 30 are disposed on the whitening stabilizing layer 20 at intervals; the number of backing layers 40 is equal to the number of whitening layers 30 and one-to-one covers the whitening layers 30. Thus, having a plurality of whitening layers 30 and backing layers 40 on one release layer 10 improves ease of use.

The preparation method of the tooth whitening film 100 according to an embodiment of the present invention includes the following steps: mixing and stirring water, a penetration enhancer, a polydimethylsiloxane crosslinked polymer and a pH buffer agent uniformly, heating to 70-80 ℃, adding polyvinyl alcohol, carbon fiber and hydrogenated dimer (linolenate) carbonate-dimethyl carbonate copolymer, stirring uniformly to obtain whitening stable slurry, cooling the whitening stable slurry, coating the whitening stable slurry on a stripping layer 10 to form a whitening stable layer 20, and sequentially forming a whitening layer 30 and a backing layer 40 on the whitening stable layer 20 to obtain the tooth whitening adhesive film 100.

The preparation method of the tooth whitening film of the embodiment is simple to operate and easy to realize, the prepared tooth whitening film 100 is simple and convenient to use, has a longer shelf life, can ensure good tooth whitening care effect in a longer time, and has lower tooth whitening care cost.

The following are specific examples.

Example 1

Weighing the following raw materials in percentage by mass: 50.5% of water, 40% of ethanol, 3% of polyvinyl alcohol (PVA-217), 1.5% of carbon fiber, 1% of hydrogenated dimer linolic carbonate-dimethyl carbonate copolymer, 1% of polydimethylsiloxane cross-linked polymer, 0.5% of sodium dihydrogen phosphate, 0.5% of sodium phosphate and 2% of polyvinylpyrrolidone (PVP-K60). Mixing and stirring water, ethanol, polydimethylsiloxane cross-linked polymer, sodium dihydrogen phosphate and sodium phosphate uniformly, heating to 70-80 ℃, adding polyvinyl alcohol, carbon fiber, hydrogenated dimer (oleyl alcohol) carbonate-dimethyl carbonate copolymer and polyvinylpyrrolidone, stirring uniformly to obtain whitening stable slurry, wherein the pH (25 ℃) is 6.3, the viscosity is 8500 mPa.s (NDJ-1 rotary viscometer, 25 ℃, rotor No. 3 and 12 revolutions per minute), cooling to room temperature, coating on a stripping layer, and naturally volatilizing and airing to form the whitening stable layer.

Weighing the following raw materials in percentage by mass: 47.35% of water, 30% of glycerol, 4% of sorbitol, 3% of cellulose sodium, 2% of magnesium aluminum silicate, 2% of sodium lignin sulfonate, 1.5% of VP-hexadecene copolymer, 0.8% of xanthan gum, 8% of hydrogen peroxide, 1% of silicon dioxide, 0.1% of disodium ethylenediamine tetraacetate, 0.2% of menthol and 0.05% of essence. Adding water, glycerol, sorbitol, sodium cellulose, aluminum magnesium silicate, sodium lignosulfonate, VP-hexadecene copolymer, xanthan gum and menthol into an emulsifying pot, stirring uniformly, heating to 70-80 ℃, cooling to normal temperature, adding hydrogen peroxide, silicon dioxide, disodium ethylenediamine tetraacetate and essence into the emulsifying pot, stirring uniformly to form a viscous colloid, coating the viscous colloid on a whitening stable layer to form a whitening layer, and forming a backing layer on the whitening layer through the processes of film coating, film rolling, standing, settling, slicing and the like to obtain the tooth whitening film. Table 1 shows the shelf life test results of the tooth whitening strip film of this example, and it can be seen that the shelf life of the tooth whitening strip film of this example is more than two years.

TABLE 1

Example 2

Weighing the following raw materials in percentage by mass: 50% of water, 40% of ethanol, 4% of polyvinyl alcohol (PVA-217), 2% of carbon fiber, 1.5% of hydrogenated dimer linolic carbonate-dimethyl carbonate copolymer, 1.5% of polydimethylsiloxane crosslinked polymer, 0.5% of sodium dihydrogen phosphate and 0.5% of sodium phosphate. Mixing and stirring water, ethanol, polydimethylsiloxane cross-linked polymer, sodium dihydrogen phosphate and sodium phosphate uniformly, heating to 70-80 ℃, adding polyvinyl alcohol, carbon fiber and hydrogenated dimer (linolenate) carbonate-dimethyl carbonate copolymer, stirring uniformly to obtain whitening stable slurry, wherein the pH (25 ℃) is 6.8, the viscosity is 7300 mPa.s (NDJ-1 rotary viscometer, 25 ℃, rotor No. 3 and 12 r/min), cooling to room temperature, coating on a stripping layer, and naturally volatilizing and airing to form the whitening stable layer.

Weighing the following raw materials in percentage by mass: 34.45% of water, 35% of glycerol, 5% of propylene glycol, 4% of ethanol, 2.5% of sodium cellulose, 3% of VP-hexadecene copolymer, 2.5% of chitin, 2% of carbon fiber, 2.5% of chlorine dioxide, 2.5% of sodium bicarbonate, 2% of kieselguhr, 2% of polyvinylpyrrolidone, 2% of xylitol, 0.2% of sodium phytate, 0.15% of disodium edetate and 0.2% of menthol. Adding water, glycerol, propylene glycol, sodium cellulose, VP-hexadecene copolymer, chitin, carbon fiber, polyvinylpyrrolidone and menthol into an emulsifying pot, stirring uniformly, heating to 70-80 ℃, cooling to normal temperature, adding ethanol, chlorine dioxide, sodium bicarbonate, diatomite, xylitol, sodium phytate, disodium ethylenediamine tetraacetate and menthol into the emulsifying pot, stirring uniformly to form a viscous colloid, coating the viscous colloid on a whitening stable layer to form a whitening layer, and forming a backing layer on the whitening layer through the processes of film coating, film rolling, standing, settling, slicing and the like to obtain the tooth whitening film. Table 2 shows the shelf life test results of the tooth whitening strip film of this example, and it can be seen that the shelf life of the tooth whitening strip film of this example is more than two years.

TABLE 2

Example 3

The preparation method of this example is basically the same as that of example 1, except that the raw material ratio of the whitening stable slurry is: 57.1% water, 32% ethanol, 0.5% polyvinyl alcohol (PVA-217), 0.5% carbon fiber, 0.8% hydrogenated dimer (linolenate) carbonate-dimethyl carbonate copolymer, 0.8% polydimethylsiloxane cross-linked polymer, 1.1% sodium dihydrogen phosphate, 0.2% sodium phosphate and 7% polyvinylpyrrolidone (PVP-K60), the pH (25 ℃) of the whitening stabilizing slurry was 3.6, and the viscosity was 19300 mPas (NDJ-1 rotary viscometer, 25 ℃, rotor No. 3, 12 rpm). Table 3 shows the shelf life test results of the tooth whitening mask of this example, and it can be seen that the shelf life of the tooth whitening mask of this example is more than one and half a year.

TABLE 3 Table 3

Example 4

The preparation method of this example is basically the same as that of example 1, except that the raw material ratio of the whitening stable slurry is: 30.3% of water, 60% of ethanol, 2% of polyvinyl alcohol (PVA-217), 3.5% of carbon fiber, 2.2% of hydrogenated dimer (linolenyl carbonate) -dimethyl carbonate copolymer, 0.8% of polydimethylsiloxane cross-linked polymer, 0.2% of sodium dihydrogen phosphate and 1.0% of sodium phosphate, and the pH (25 ℃) of the whitening stabilizing slurry was 9.6 and the viscosity was 4300 mPas (NDJ-1 rotary viscometer, 25 ℃, rotor No. 3, 12 rpm). Table 4 shows the shelf life test results of the tooth whitening mask of this example, and it can be seen that the shelf life of the tooth whitening mask of this example is more than one and half a year.

TABLE 4 Table 4

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Example 5

The preparation method of this example is basically the same as that of example 1, except that the raw material ratio of the whitening stable slurry is: 46.2% of water, 43% of ethanol, 2.5% of polyvinyl alcohol (PVA-217), 1.5% of carbon fiber, 1.2% of hydrogenated dimer (linolenate) carbonate-dimethyl carbonate copolymer, 1.5% of polydimethylsiloxane cross-linked polymer, 0.8% of sodium dihydrogen phosphate, 0.3% of sodium phosphate and 3% of polyvinylpyrrolidone (PVP-K60), and the pH (25 ℃) of the whitening stable slurry is 4.3, and the viscosity is 8300 mPas (NDJ-1 rotary viscometer, 25 ℃, rotor No. 3, 12 rpm). Table 5 shows the shelf life test results of the tooth whitening strip film of this example, and it can be seen that the shelf life of the tooth whitening strip film of this example is more than two years.

TABLE 5

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Example 6

The preparation of this example was essentially the same as that of example 5, except that the pH (25 ℃) of the whitening stabilizing slurry was adjusted to 8.6 and the viscosity was adjusted to 13200 mPa.s (NDJ-1 rotary viscometer, 25 ℃, rotor No. 3, 12 rpm). Table 6 shows the shelf life test results of the tooth whitening strip film of this example, and it can be seen that the shelf life of the tooth whitening strip film of this example is more than two years.

TABLE 6

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Comparative example 1

The preparation method of this comparative example was substantially the same as in example 1, except that the tooth whitening strip prepared did not include a whitening stabilizing layer. Table 7 shows the shelf life test results of the tooth whitening mask of the comparative example, and the shelf life of the tooth whitening mask of the comparative example is less than one and half years.

TABLE 7

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Comparative example 2

The preparation method of this comparative example is basically the same as that of example 1, except that the raw material ratio of the whitening stable slurry is: 50.5% of water, 40% of ethanol, 5.5% of polyvinyl alcohol (PVA-217), 1% of polydimethylsiloxane cross-linked polymer, 0.5% of sodium dihydrogen phosphate, 0.5% of sodium phosphate and 2% of polyvinylpyrrolidone (PVP-K60). Table 8 shows the shelf life test results of the tooth whitening mask of the comparative example, and the shelf life of the tooth whitening mask of the comparative example is less than one and half years.

TABLE 8

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The whitening effect test was performed using the tooth whitening patches (stored for 22 months) of example 1, example 2, comparative example 1 and comparative example 2, and the number of persons participating in the test was 2000 persons, divided into four groups of A, B, C, D, each group being 500 persons. Group a used the tooth whitening patch of example 1, group B used the tooth whitening patch of example 2, group C used the tooth whitening patch of comparative example 1, and group D used the tooth whitening patch of comparative example 2. The test staff sticks the product for 2 times every day, and each time sticks 25min, and the comparison is carried out before and after whitening teeth for 15 days, and the result shows that the group A crowd averagely improves 9 color levels, the group B crowd averagely improves 8 color levels, the group C crowd averagely improves 5 color levels, and the group D crowd averagely improves 6 color levels, so that the tooth whitening film of the embodiment can ensure good tooth whitening nursing effect in a longer time.

The technical features of the above-described embodiments may be arbitrarily combined, and all possible combinations of the technical features in the above-described embodiments are not described for brevity of description, however, as long as there is no contradiction between the combinations of the technical features, they should be considered as the scope of the description.

The above examples illustrate only a few embodiments of the invention, which are described in detail and are not to be construed as limiting the scope of the invention. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the invention, which are all within the scope of the invention. Accordingly, the scope of protection of the present invention is to be determined by the appended claims.

Claims

1. The whitening stable slurry is characterized by being prepared from the following raw materials in percentage by mass: 30 to 70 percent of water, 25 to 65 percent of penetration enhancer, 0.5 to 8 percent of polyvinyl alcohol, 0.5 to 4 percent of carbon fiber, 0.5 to 4 percent of hydrogenated dimer (linolen) carbonate-dimethyl carbonate copolymer, 0.5 to 3 percent of polydimethylsiloxane crosslinked polymer and 0.2 to 2 percent of pH buffer;

the pH value of the whitening stable slurry is 4-9;

the viscosity of the whitening stable slurry is 5000 mPas to 15000 mPas.

2. The whitening stable slurry according to claim 1, which is mainly prepared from the following raw materials in percentage by mass: 45-55% of water, 35-45% of penetration enhancer, 3-6% of polyvinyl alcohol, 1-3% of carbon fiber, 1-2% of hydrogenated dimer (linolenate) carbonate-dimethyl carbonate copolymer, 1-2% of polydimethylsiloxane crosslinked polymer and 0.6-1.6% of pH buffer.

3. The whitening stabilization slurry according to claim 1 or 2, wherein the penetration enhancer is ethanol and the pH buffering agent is sodium dihydrogen phosphate and sodium phosphate.

4. A tooth whitening patch comprising a release layer, a whitening stabilizing layer, a whitening layer and a backing layer, which are laminated in this order, wherein the whitening stabilizing layer is formed from the whitening stabilizing slurry according to any one of claims 1 to 3.

5. The tooth whitening film as set forth in claim 4, wherein the whitening layer is prepared mainly from the following raw materials: a thickener, a humectant, a whitening agent, a flavoring agent, a chelating agent, a pH regulator, a flavoring agent and water.

6. The tooth whitening film of claim 5, wherein the thickening agent is one or more of magnesium aluminum silicate, chitin, sodium lignin sulfonate, VP-hexadecene copolymer, lignin fiber, carbon fiber, polyvinylpyrrolidone, sodium cellulose, polyvinyl alcohol, ethylcellulose, carbomer, pectin, xanthan gum, and gelatin.

7. The tooth whitening film of claim 5, wherein the whitening agent is one or more of hydrogen peroxide, peracetic acid, carbamide peroxide, sodium bicarbonate, sodium carbonate, chlorine dioxide, linoleic acid, fruit acid, silica, charcoal, and diatomaceous earth.

8. A method for preparing a tooth whitening patch according to any one of claims 4 to 7, comprising the steps of: mixing and stirring water, a penetration enhancer, a polydimethylsiloxane crosslinked polymer and a pH buffer agent uniformly, heating to 70-80 ℃, adding polyvinyl alcohol, carbon fiber and hydrogenated dimer (linolic acid) carbonate-dimethyl carbonate copolymer, and stirring uniformly to obtain whitening stable slurry, cooling the whitening stable slurry, coating the whitening stable slurry on the stripping layer to form the whitening stable layer, and sequentially forming the whitening layer and the backing layer on the whitening stable layer to obtain the tooth whitening adhesive film.