CN110721118A

CN110721118A - Whitening tooth paste and preparation method thereof

Info

Publication number: CN110721118A
Application number: CN201911046489.5A
Authority: CN
Inventors: 林宇祺; 赵洁
Original assignee: Guangzhou Wei Qi Biological Technology Co Ltd
Current assignee: Guangzhou Wei Qi Biological Technology Co Ltd
Priority date: 2019-10-30
Filing date: 2019-10-30
Publication date: 2020-01-24

Abstract

The invention discloses a whitening tooth paste which is prepared from the following raw materials in percentage by weight: 5-15% of gelling agent, 1-10% of gelling agent, 5-20% of humectant, 1-10% of solubilizer, 1-20% of whitening agent and the balance of absolute ethyl alcohol; the gelatinizing agent is one of a thermoplastic polyurethane elastomer, a styrene-ethylene-butylene-styrene block copolymer, a styrene-butadiene block copolymer, a styrene-isoprene-styrene block copolymer, ethylene propylene diene monomer, thermoplastic polyolefin, thermoplastic vulcanized rubber, silicone rubber, polyamide and thermoplastic acrylic acid, and the gelatinizing agent is a polyether type thermoplastic polyurethane elastomer; the invention also discloses a preparation method of the whitening tooth paste; the whitening tooth paste prepared by the invention has good stability and strong water resistance, can ensure that the whitening agent in the whitening tooth paste acts on teeth for a longer time, and has more obvious whitening effect.

Description

Whitening tooth paste and preparation method thereof

Technical Field

The invention relates to the technical field of oral care, in particular to a whitening tooth paste and a preparation method thereof.

Background

With the improvement of living standard of people, many people pay more and more attention to tooth beauty, and tooth beauty products are various and comprise a tooth whitening pen, a tooth whitening tray, a tooth whitening suit, a whitening tooth paste and the like. The construction of whitening strips generally comprises: a plastic film layer, a gel layer, and a release backing layer. The gel layer contains teeth whitening functional substance, and is closely connected with the plastic film layer, when in use, the stripping back lining layer is torn off, one side with the gel layer is well pasted on the surface of the teeth, the tooth paste is adjusted by slightly pressing with fingers to be completely pasted on the surface of the teeth, and after use, the tooth paste is taken out of the teeth and discarded. The whitening tooth paste is favored by consumers due to the advantages of convenient carrying, simple use, low price and the like.

Hydrogen peroxide has been used for tooth whitening for 40 years, has higher effect and safety than other tooth whitening components, and is still a common or auxiliary active component in household tooth whitening products and professional tooth whitening modes at present. The conventional whitening strip has the following two problems: 1. hydrogen peroxide oxidizes the binder in the product formulation, resulting in collapse of the gel skeleton structure and poor product stability over time; 2. the water resistance of the gel layer of the tooth paste is poor, so that the action time of hydrogen peroxide on teeth is short, the whitening effect is not obvious, and the requirements of users cannot be met. Therefore, how to make the tooth paste not diluted by water-based saliva to cause rapid dissolution by improving the water resistance of the gel layer of the tooth paste, and ensure the action time of hydrogen peroxide on teeth, thereby obtaining better whitening effect is a problem to be solved urgently in the industry.

Disclosure of Invention

Aiming at the defects of the prior art, the invention aims to provide the whitening tooth paste which is strong in water resistance, good in stability and good in whitening effect.

In order to achieve the purpose, the invention adopts the following technical scheme:

a whitening tooth paste is composed of the following raw materials in percentage by weight: 5-15% of gelling agent, 1-10% of gelling agent, 5-20% of humectant, 1-10% of solubilizer, 1-20% of whitening agent and the balance of absolute ethyl alcohol; the gelatinizing agent is one of thermoplastic polyurethane elastomer, styrene-ethylene-butylene-styrene block copolymer, styrene-butadiene block copolymer, styrene-isoprene-styrene block copolymer, ethylene propylene diene monomer, thermoplastic polyolefin, thermoplastic vulcanized rubber, silicone rubber, polyamide and thermoplastic acrylic acid.

Preferably, the material consists of the following raw materials in percentage by weight: 10% of gelling agent, 5% of gelling agent, 12% of humectant, 5% of solubilizer, 10% of whitening agent and the balance of absolute ethyl alcohol.

Preferably, the material consists of the following raw materials in percentage by weight: 5% of gelling agent, 1% of gelling agent, 5% of humectant, 1% of solubilizer, 1% of whitening agent and the balance of absolute ethyl alcohol.

Preferably, the material consists of the following raw materials in percentage by weight: 15% of gelling agent, 10% of gelling agent, 20% of humectant, 10% of solubilizer, 20% of whitening agent and the balance of absolute ethyl alcohol.

Preferably, the gelatinizing agent is a polyether type thermoplastic polyurethane elastomer.

The thermoplastic polyurethane elastomer is also called thermoplastic polyurethane rubber, TPU for short, and is An (AB) n type block linear polymer, wherein A is polyester or polyether with high molecular weight (1000-6000), B is diol containing 2-12 straight chain carbon atoms, and the chemical structure between AB chain segments is diisocyanate. TPU relies on intermolecular hydrogen bond crosslinking or macromolecular interchain slight crosslinking, and the two crosslinking structures have reversibility along with the increase or decrease of temperature. The intermolecular force is weakened in a molten state or a solution state, and the intermolecular force is strongly connected together after cooling or solvent volatilization, so that the performance of the original solid is recovered. The linear polyurethane has physical crosslinking formed by a plurality of hydrogen bonds among molecular chains, and the hydrogen bonds have a strengthening effect on the form of the linear polyurethane, so that a plurality of excellent performances such as high modulus, high strength, excellent wear resistance, chemical resistance, hydrolysis resistance, high low temperature resistance and high mold resistance are endowed. These good properties have led to widespread use of TPU in many areas such as shoe materials, cables, garments, automobiles, medical and health, tubing, films and sheets. TPU is receiving more and more attention as a medical material, and various medical TPU is rapidly developed. In the early 80 s of the last century, the artificial heart transplantation operation made of TPU has been successful, so that TPU materials are further developed in the field of biomedicine. At present, medical products developed by applying TPU mainly comprise artificial heart auxiliary devices, artificial blood vessels and various catheters.

The thermoplastic polyurethane elastomer comprises polyester and polyether, the polyether thermoplastic polyurethane elastomer is preferably used as a gelling agent, and the hydrolysis stability of the gelling agent is far higher than that of the polyester, so that the dental paste prepared from the polyether thermoplastic polyurethane elastomer has stronger water resistance and higher tolerance to peroxide.

Preferably, the gelling agent is one or a mixture of more than two of polyvinylpyrrolidone, sodium polyacrylate, carbomer, xanthan gum, carrageenan, gum arabic, pectin, sodium carboxymethylcellulose and hydroxyethyl cellulose.

Preferably, the gelling agent is a mixture of polyvinylpyrrolidone, carrageenan and sodium carboxymethylcellulose.

Preferably, the humectant is one or a mixture of two or more of glycerin, propylene glycol, polyethylene glycol and butanediol, the solubilizer is one or a mixture of two or more of PEG-40 hydrogenated castor oil, PEG-60 hydrogenated castor oil, coco-polyether-7 and polysorbate-20, and the whitening agent is one or a mixture of two or more of hydrogen peroxide, urea peroxide, sodium perborate, sodium percarbonate, calcium chlorite, barium chlorite, magnesium chlorite, aluminum chlorite, sodium chlorite, potassium chlorite, sodium hypochlorite, zinc citrate and sodium phytate.

Preferably, the whitening agent is a 35% hydrogen peroxide solution.

On the other hand, the invention also provides a preparation method of the whitening tooth paste, which comprises the following steps:

(1) uniformly mixing the gelling agent, the solubilizer and the humectant, heating to 130-150 ℃ until the gelling agent, the solubilizer and the humectant are completely dissolved to obtain an agent A, and cooling to 70-80 ℃ for later use;

(2) dissolving the gel in anhydrous ethanol to obtain agent B, adding agent B into agent A, stirring, cooling to 25-30 deg.C, adding whitening agent, and mixing to obtain mixed viscous colloid;

(3) and coating the mixed adhesive colloid on a stripping back lining layer, covering a plastic film layer, and preparing the whitening tooth paste through processes of slitting, indentation, waste collection and cutting.

Compared with the prior art, the invention has the beneficial technical effects that:

according to the whitening tooth paste, the polyether type thermoplastic polyurethane elastomer is added to serve as the gelling agent, and the proportion of each raw material component is optimized, so that the skeleton structure of the gel layer is compact, the product stability is good, the water resistance is high, the whitening agent in the whitening tooth paste is enabled to act on teeth for a longer time, and the whitening effect is more obvious; the preparation method is simple and easy to implement, the production cost is low, the hydrogen peroxide is added at the normal temperature, the influence of high temperature on the stability of the hydrogen peroxide is avoided, and the whitening effect can be exerted to the maximum extent.

Detailed Description

The following further describes the embodiments of the present invention. It should be noted that the description of the embodiments is provided to help understanding of the present invention, but the present invention is not limited thereto. In addition, the technical features involved in the embodiments of the present invention described below may be combined with each other as long as they do not conflict with each other.

The formulations of the whitening strips prepared in examples 1-3 and comparative examples 1-2 of the present invention are shown in table 1 below, and the content units of the raw materials in table 1 below are weight percentages.

TABLE 1

The preparation method of the whitening tooth paste in the embodiment 1 comprises the following steps of raw materials in percentage by weight in a table 1:

(1) uniformly mixing polyether type thermoplastic polyurethane elastomer, PEG-40 hydrogenated castor oil and glycerol, heating to 130 ℃ until the mixture is completely dissolved to obtain an agent A, and cooling to 70 ℃ for later use;

(2) dissolving polyvinylpyrrolidone in absolute ethyl alcohol to obtain a B agent, adding the B agent into the A agent, stirring uniformly, cooling to 25 ℃, adding hydrogen peroxide, and mixing uniformly to obtain a mixed viscous colloid;

Example 2 a method for preparing a whitening strip, the raw materials are in the weight percentages in table 1, and the method comprises the following steps:

(1) uniformly mixing polyether type thermoplastic polyurethane elastomer, PEG-40 hydrogenated castor oil, polysorbate-20, glycerol, propylene glycol and butanediol, heating to 140 ℃ until the mixture is completely dissolved to obtain a preparation A, and cooling to 75 ℃ for later use;

(2) dissolving polyvinylpyrrolidone in absolute ethyl alcohol to obtain a B agent, adding the B agent into the A agent, stirring uniformly, cooling to 28 ℃, adding hydrogen peroxide, and mixing uniformly to obtain a mixed viscous colloid;

Example 3 a method for preparing a whitening strip, the raw materials are in the weight percentages in table 1, and the method comprises the following steps:

(1) uniformly mixing polyether type thermoplastic polyurethane elastomer, PEG-60 hydrogenated castor oil, coconut oil alcohol polyether-7, glycerol and polyethylene glycol, heating to 150 ℃ until the mixture is completely dissolved to obtain an agent A, and cooling to 80 ℃ for later use;

(2) dissolving polyvinylpyrrolidone, carrageenan and sodium carboxymethylcellulose in absolute ethyl alcohol to obtain a preparation B, adding the preparation B into the preparation A, stirring uniformly, cooling to 30 ℃, adding hydrogen peroxide, and mixing uniformly to obtain a mixed viscous colloid;

The difference between comparative example 1 and example 2 is that comparative example 1 equally replaces the polyether thermoplastic polyurethane elastomer with polyvinylpyrrolidone, comparative example 1 does not contain the polyether thermoplastic polyurethane elastomer, and the other preparation conditions and methods are the same as those of example 2.

Comparative example 2 is different from example 1 in that comparative example 2 has a reduced amount of polyether type thermoplastic polyurethane elastomer added, and other preparation conditions and methods are the same as those of example 1.

Performance testing and evaluation

The whitening strips prepared in examples 1 to 3 and comparative examples 1 to 2 were subjected to a water resistance test and a stability test, respectively, and a certain type of commercially available whitening strip was used as a control group, and the test results are shown in table 2 below.

1. Water resistance test method: taking a transparent beaker, adding warm water at about 40 ℃, respectively tearing off the whitening tooth pastes prepared in the examples 1-3 and the comparative examples 1-2 from the stripping back lining layer, sticking the whitening tooth pastes on a glass slide, and sinking the glass slide with the tooth pastes in the water, wherein the water temperature is controlled at 40 ℃. The time of dissolution was recorded by visually observing the rate of tooth paste dissolution with a IKARW20 mixer while continuing the mixing at 300 rpm.

Evaluation criteria: the gel layer of the tooth paste is slowly decomposed and dissolved, and finally falls off from the glass slide, so that the water resistance of the tooth paste is poor; the gel layer of the tooth paste is kept intact all the time and is firmly adhered to the glass slide, so that the tooth paste has good water resistance.

2. The product stability test method comprises the following steps: when the whitening strips prepared in examples 1-3 and comparative examples 1-2 were placed in a 60 ℃ incubator, respectively, the hydrogen peroxide would become abnormally active, which explains the strong gas burst that occurs with the released gas.

Evaluation criteria: the dental paste can be endured for 20 days at the high temperature of 60 ℃ without generating flatulence, so that the dental paste has good stability and lasting whitening effect; when the situation of flatulence occurs, the tooth paste has poor stability and short whitening effect.

TABLE 2

As can be seen from table 2, the whitening strips prepared in examples 1-3 had water resistance and stability higher than those of comparative examples 1-2 and commercially available whitening strips; compared with the embodiment 2, the whitening tooth paste prepared in the comparative example 1 does not contain the polyether type thermoplastic polyurethane elastomer, so that the product basically does not have water resistance, is easy to have the phenomenon of flatulence and has poor product stability; compared with the example 1, the comparative example 2 has the defects that the water resistance of the product is poor and the stability of the product is lower than that of the example 1 due to the fact that the adding amount of the polyether type thermoplastic polyurethane elastomer is reduced. The whitening tooth paste disclosed by the invention is characterized in that the polyether type thermoplastic polyurethane elastomer is added as a gelling agent, and the proportion of each raw material component is optimized, so that the product is better in stability and stronger in water resistance, and a better whitening effect is achieved.

The embodiments of the present invention have been described in detail, but the present invention is not limited to the described embodiments. It will be apparent to those skilled in the art that various changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, and the scope of protection is still within the scope of the invention.

Claims

1. The whitening tooth paste is characterized by comprising the following raw materials in percentage by weight: 5-15% of gelling agent, 1-10% of gelling agent, 5-20% of humectant, 1-10% of solubilizer, 1-20% of whitening agent and the balance of absolute ethyl alcohol; the gelatinizing agent is one of thermoplastic polyurethane elastomer, styrene-ethylene-butylene-styrene block copolymer, styrene-butadiene block copolymer, styrene-isoprene-styrene block copolymer, ethylene propylene diene monomer, thermoplastic polyolefin, thermoplastic vulcanized rubber, silicone rubber, polyamide and thermoplastic acrylic acid.

2. The whitening strip according to claim 1, which is prepared from the following raw materials in percentage by weight: 10% of gelling agent, 5% of gelling agent, 12% of humectant, 5% of solubilizer, 10% of whitening agent and the balance of absolute ethyl alcohol.

3. The whitening strip according to claim 1, which is prepared from the following raw materials in percentage by weight: 5% of gelling agent, 1% of gelling agent, 5% of humectant, 1% of solubilizer, 1% of whitening agent and the balance of absolute ethyl alcohol.

4. The whitening strip according to claim 1, which is prepared from the following raw materials in percentage by weight: 15% of gelling agent, 10% of gelling agent, 20% of humectant, 10% of solubilizer, 20% of whitening agent and the balance of absolute ethyl alcohol.

5. The whitening strip of any one of claims 1 to 4, wherein the gelling agent is a polyether type thermoplastic polyurethane elastomer.

6. The whitening strip according to any one of claims 1 to 4, wherein the gelling agent is one or a mixture of two or more of polyvinylpyrrolidone, sodium polyacrylate, carbomer, xanthan gum, carrageenan, gum arabic, pectin, sodium carboxymethylcellulose, and hydroxyethylcellulose.

7. The whitening strip of claim 6, wherein the gelling agent is a mixture of polyvinylpyrrolidone, carrageenan and sodium carboxymethylcellulose.

8. The whitening strip according to any one of claims 1 to 4, wherein the humectant is one or a mixture of two or more of glycerin, propylene glycol, polyethylene glycol and butylene glycol, the solubilizer is one or a mixture of two or more of PEG-40 hydrogenated castor oil, PEG-60 hydrogenated castor oil, coco-alcohol polyether-7 and polysorbate-20, and the whitening agent is one or a mixture of two or more of hydrogen peroxide, urea peroxide, sodium perborate, sodium percarbonate, calcium chlorite, barium chlorite, magnesium chlorite, aluminum chlorite, sodium chlorite, potassium chlorite, sodium hypochlorite, zinc citrate and sodium phytate.

9. The whitening strip of claim 8, wherein the whitening agent is a 35% hydrogen peroxide solution.

10. A method for preparing a whitening strip according to any one of claims 1 to 9, comprising the steps of: