CN108072951B - Optical filter switching device - Google Patents

Optical filter switching device Download PDF

Info

Publication number
CN108072951B
CN108072951B CN201611027868.6A CN201611027868A CN108072951B CN 108072951 B CN108072951 B CN 108072951B CN 201611027868 A CN201611027868 A CN 201611027868A CN 108072951 B CN108072951 B CN 108072951B
Authority
CN
China
Prior art keywords
plate
optical filter
sliding
fixed
bottom plate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201611027868.6A
Other languages
Chinese (zh)
Other versions
CN108072951A (en
Inventor
盛司潼
冯传发
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangzhou Considerin Gene Health Technology Co ltd
Original Assignee
Guangzhou Considerin Gene Health Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangzhou Considerin Gene Health Technology Co ltd filed Critical Guangzhou Considerin Gene Health Technology Co ltd
Priority to CN201611027868.6A priority Critical patent/CN108072951B/en
Publication of CN108072951A publication Critical patent/CN108072951A/en
Application granted granted Critical
Publication of CN108072951B publication Critical patent/CN108072951B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B7/00Mountings, adjusting means, or light-tight connections, for optical elements
    • G02B7/006Filter holders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Mechanical Light Control Or Optical Switches (AREA)

Abstract

The invention relates to the technical field of optical adjusting instruments, and provides an optical filter switching device which comprises a base, a sliding assembly, a driving assembly and at least one pair of optical filter fixing frames for installing optical filters, wherein the sliding assembly is arranged on the base; the sliding assembly comprises a sliding plate, a sliding block and a sliding rail, the base comprises a bottom plate and a sliding rail mounting plate vertical to the bottom plate, and the sliding rail is fixed on the sliding rail mounting plate; the sliding plate comprises a first transverse plate and a connecting plate vertical to the first transverse plate, the optical filter fixing frame is fixed on the first transverse plate, the bottom plate is provided with a sliding groove, and the first transverse plate is positioned in the sliding groove; the sliding block is fixed on the connecting plate and is arranged on the sliding rail in a sliding manner; the driving assembly is arranged on the bottom plate and used for driving the first transverse plate to move in the sliding groove; the invention has the beneficial effects that: the optical filter switching device is compact in structure, convenient to install in a limited space inside the sequencer and capable of solving the problem that the optical filter switching device is difficult to install.

Description

Optical filter switching device
Technical Field
The invention relates to the technical field of optical adjusting instruments, in particular to an optical filter switching device.
Background
The advent of DNA sequencing technology, which is the most commonly used technique in molecular biology research, has greatly driven the development of biology. The development of second generation DNA sequencing technology in recent years has made DNA sequencing into a high throughput, low cost era. The high-throughput DNA sequencing technology is a revolutionary improvement of the traditional sequencing technology, and can simultaneously sequence millions or even tens of millions of DNA sequences at a time. In the existing sequencing technology, a sequencing reaction is carried out by adopting a four-color labeled raw material through a connection sequencing method adopting a labeled probe or a synthetic sequencing method adopting labeled nucleotide.
In the process of implementing the sequencing reaction, an optical instrument is required to capture a fluorescence signal in the sequencing reaction process, and optical filters with various specifications are required to be installed in the optical instrument to filter fluorescence, so an optical filter switching device is required to be installed; since the space for installing the filter switching device inside the sequencer is limited, the structure of the filter switching device is difficult to design.
There is therefore a need for a new filter switching device that is compact and convenient to install in the confined space inside a sequencer.
Disclosure of Invention
The invention aims to provide an optical filter switching device, and aims to solve the problems that the space for installing the optical filter switching device in a sequencer is limited and the optical filter switching device is difficult to install in the prior art.
In order to achieve the object of the present invention, an optical filter switching device is improved by comprising:
the base comprises a bottom plate and a slide rail mounting plate vertical to the bottom plate, and a slide groove is formed in the bottom plate;
the sliding assembly comprises a sliding plate, a sliding block and a sliding rail, the sliding plate comprises a first transverse plate positioned in the sliding groove and a connecting plate perpendicular to the first transverse plate, the sliding rail is fixed on the sliding rail mounting plate, the sliding block is fixed on the connecting plate, and the sliding block is arranged on the sliding rail in a sliding manner;
the optical filter fixing frames are fixed on the first transverse plate and are used for installing optical filters and are at least one pair;
and the driving assembly is arranged on the bottom plate and is used for driving the first transverse plate to move in the sliding groove.
In the structure, the base further comprises a driving assembly mounting plate, the driving assembly mounting plate is parallel to the bottom plate or is positioned on the same plane, the sliding rail mounting plate is positioned between the bottom plate and the driving assembly mounting plate, and the driving assembly is mounted on the driving assembly mounting plate.
Furthermore, the sliding plate is Z-shaped, and the sliding plate also comprises a second transverse plate vertical to the connecting plate;
the driving assembly comprises a motor, a rotating gear and a rack, the motor is fixed on the driving assembly mounting plate, and the rotating gear is mounted on an output shaft of the motor; the rack is arranged on the second transverse plate and meshed with the rotating gear.
Furthermore, the optical filter switching device also comprises a front panel and a cover plate;
the base still includes two curb plates that are located bottom plate both ends and perpendicular to bottom plate, the apron is fixed the top of curb plate is provided with relative spacing draw-in groove on two curb plates, the both ends of front panel insert in the spacing draw-in groove of two curb plates, be provided with the light entry on the front panel, be provided with the light export on apron and the bottom plate.
Furthermore, first shading sheets are fixedly arranged at two ends of the connecting plate, and first photoelectric detectors are correspondingly and respectively arranged on the inner walls of the two side plates;
the middle part fixed mounting of second diaphragm has the second anti-dazzling screen, what correspond on the drive assembly mounting panel installs the second photoelectric detector.
Furthermore, a positioning ball plunger is installed in the sliding groove of the bottom plate, a plurality of alignment grooves are formed in the lower surface of the first transverse plate, the first transverse plate slides in the sliding groove and is abutted against the alignment grooves through the positioning ball plunger, and the first transverse plate is positioned.
In the structure, the optical filter fixing frame is a hollow structure with an opening at the top, and a reflecting sheet is arranged in the optical filter fixing frame;
the optical filter fixing frame is provided with a bottom surface and a front surface, a first optical filter fixing hole communicated with the interior is formed in the front surface, and a first optical filter is fixed in the first optical filter fixing hole;
and a second optical filter fixing hole communicated with the inside is formed in the bottom surface, and a second optical filter is fixed in the second optical filter fixing hole.
Furthermore, a first fixing block and a second fixing block are fixed on the first transverse plate, a guide groove is formed between the first fixing block and the second fixing block, and the optical filter fixing frame is fixed in the guide groove.
Furthermore, the first fixed block is provided with a first inner surface attached to the optical filter fixing frame, the second fixed block is provided with a second inner surface attached to the optical filter fixing frame, and included angles formed by the first inner surface and the second inner surface and the first transverse plate are acute angles.
Further, be provided with the inclined plane of laminating mutually with first internal surface, second internal surface on the light filter mount, be provided with the constant head tank on the inclined plane, be provided with a shop bolt on the second fixed block, and be provided with a spring between shop bolt fixed and the second fixed block, the light filter mount is fixed at the guide way after, shop bolt's top card is gone into the constant head tank in.
Furthermore, a light blocking sheet is further installed on the second fixing block.
According to the optical filter switching device, under the action of the driving assembly, the first transverse plate drives the optical filter fixing frame to slide left and right in the sliding groove, the optical filter switching device is compact in structure, installation in a limited space inside a sequencer is facilitated, and the problem that the optical filter switching device is difficult to install is solved.
Drawings
Fig. 1 is a schematic perspective view of a filter switching device according to an embodiment of the present invention.
Fig. 2 is a schematic perspective view of a filter switching device according to an embodiment of the present invention.
Fig. 3 is a schematic structural diagram of a base of a filter switching device according to an embodiment of the present invention.
Fig. 4 is a schematic diagram of an internal structure of a filter switching device according to an embodiment of the present invention.
Fig. 5 is a schematic structural diagram of a sliding assembly and a driving assembly of the filter switching device according to an embodiment of the present invention.
Fig. 6 is a schematic view of a sliding plate of the filter switching apparatus according to another embodiment of the present invention.
Fig. 7 is a schematic diagram of an internal structure of a filter switching device according to another embodiment of the present invention.
Fig. 8 and 9 are schematic perspective views of a sliding plate and a base according to another embodiment of the present invention.
Fig. 10 and 11 are schematic perspective views of a filter holder of a filter switching device according to an embodiment of the invention.
Fig. 12 and 13 are schematic perspective views of a sliding assembly according to another embodiment of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments.
The present invention provides a first embodiment, and the present invention provides a filter switching device, as shown in fig. 1 to 3, the filter switching device includes a base 10, a cover 20 and a front panel 30. The base 10 comprises a bottom plate 101 and two side plates 102 which are positioned at two ends of the bottom plate 101 and are perpendicular to the bottom plate 101, and the cover plate 20 is fixed at the top ends of the side plates 102; one end of each of the two side plates 102 in the same direction is bent towards the center of the bottom plate 101 to form a limiting end 1022, the limiting ends 1022 of the two side plates 102 are provided with limiting slots 1021 with opposite opening directions, and two ends of the front panel 30 are inserted into the limiting slots 1021 of the two side plates 102 and can be pulled out of the limiting slots 1021, so that the front panel 30 can be detachably fixed. Further, still be provided with ball plunger 1023 on spacing end 1022, the top of ball plunger 1023 stretches into spacing draw-in groove 1021 in, the bottom of front panel 30 is provided with locating hole 302, inserts at the both ends of current panel 30 spacing draw-in groove 1021 in the back, in the locating hole 302 of front panel was then pushed up to the top of ball plunger 1023, realized the location and the fastening to front panel 30, it is not hard up to prevent that front panel 30 from appearing in spacing draw-in groove 1021. A ball plunger is also arranged in the limiting clamping groove 1021 of the side plate 102, and the top end of the ball plunger is pressed on the front panel 30; in addition, the front panel 30 is provided with a light inlet 301, the cover plate 20 is provided with a light outlet 201, and the bottom plate 101 is provided with a light inlet 1015.
As shown in fig. 3 to 5, the filter switching device further includes a sliding assembly 40, a driving assembly 50, and a pair of filter holders 60 for mounting the filters. In this embodiment, the sliding assembly 40 includes a sliding plate 401, a sliding block 402 and a sliding rail 403, the base 10 includes a bottom plate 101 and a sliding rail mounting plate 103 perpendicular to the bottom plate 101, the sliding rail 403 is fixed on the sliding rail mounting plate 103, specifically, a plurality of corresponding through holes are provided on the sliding rail 403 and the sliding rail mounting plate 103, the sliding rail 403 is fixedly mounted on the sliding rail mounting plate 103 by fixing screws into the through holes, and the extending direction of the sliding rail 403 is parallel to the bottom plate 101. Further, the sliding plate 401 includes a first horizontal plate 4011 and a connecting plate 4013 perpendicular to the first horizontal plate 4011, the filter holder 60 is fixed on the first horizontal plate 4011, and the bottom plate 101 is provided with a sliding groove 1011, and the first horizontal plate 4011 is located in the sliding groove 1011; the sliding block 402 is fixed on the connecting plate 4013, and the sliding block 402 is slidably arranged on the sliding rail 403; in addition, the base plate 101 further includes a driving assembly mounting plate 1012, and the driving assembly 50 is mounted on the driving assembly mounting plate 1012 and is used for driving the first horizontal plate 4011 to move in the sliding groove 1011, in this embodiment, the driving assembly mounting plate 1012 and the base plate 101 are located on the same plane, but of course, the design may be made according to actual requirements, for example, the driving assembly mounting plate 1012 is parallel to the base plate 101; the slide mounting plate 103 is positioned between the base plate 101 and the drive assembly mounting plate 1012.
Through the structure, the optical filter switching device fixes the slide rail 403 on the slide rail mounting plate 103 in the vertical direction, the slide block 402 on the connecting plate 4013 is arranged on the slide rail 403 in a sliding manner, meanwhile, the first transverse plate 4011 is arranged in the sliding groove 1011 of the base plate 101, and under the action of the driving assembly 50, the first transverse plate 4011 drives the optical filter fixing frame 60 to slide left and right in the sliding groove 1011. In the embodiment, two filter fixing frames 60 are fixed on the first horizontal plate 4011, and each filter fixing frame 60 is provided with a filter, so that the switching between the filters of two specifications can be realized.
In addition, in the embodiment, as shown in fig. 3, two ends of the driving assembly mounting plate 1012 are further provided with a side vertical plate 104, the side vertical plate 104 is perpendicular to the driving assembly mounting plate 1012, the side vertical plate 104 is perpendicular to the slide rail mounting plate 103, a fixing plate 105 protruding outwards is arranged at a corner between the side vertical plate 104 and the slide rail mounting plate 103, the fixing plate 105 is provided with a fixing hole 1051, a microscope of the sequencer is correspondingly provided with a screw hole, and the base 10 is fixed inside the sequencer by locking screws into the fixing hole 1051 and the screw hole. Due to the internal space limitation of the sequencer, the distance between the two screws on the microscope is determined, and therefore, through the design of the structures of the drive assembly mounting plate 1012, the side vertical plate 104 and the fixing plate 105, the filter switching device can be adapted to the corresponding microscope, and the internal limited space of the sequencer is reasonably utilized.
Further, in the embodiment, as for the driving assembly 50, a specific embodiment is provided in the present invention, and the driving assembly 50 includes a motor 501, a rotating gear 502, and a rack 503; in this embodiment, the sliding plate 401 further includes a second horizontal plate 4012 vertically connected to the connecting plate 4013, the first horizontal plate 4011, the connecting plate 4013 and the second horizontal plate 4012 form a Z-shaped sliding plate 401, a notch 4018 is formed at a lower corner of the second horizontal plate 4012, the rack 503 is fixed in the notch 4018 of the second horizontal plate 4012, the saw teeth of the rack 503 face the driving assembly mounting plate 1012, the motor 501 is fixed on the driving assembly mounting plate 1012, the rotating gear 502 is fixed on the output shaft of the motor 501, and the rotating gear 502 is engaged with the rack 503. In addition, a circuit board 504 is provided on the motor 501 side, and the circuit board 504 is also fixed to the drive unit mounting plate 1012, and the rotation of the motor 501 is controlled by the circuit board 504. The rotation of the motor 501 drives the gear to rotate, so that the sliding plate 401 and the sliding block 402 move on the sliding rail 403 under the action of the gear and the rack 503, the first horizontal plate 4011 slides in the sliding groove 1011 of the base plate 101, and the positions of the two filter fixing frames 60 are adjusted, thereby realizing the switching of the filters.
As for the positioning structure of the sliding plate 401, the invention provides a specific embodiment, as shown in fig. 6 and 7, two ends of the connecting plate 4013 are further fixedly mounted with first light-shielding sheets 4014, the inner walls of the two side plates 102 are correspondingly and respectively mounted with first photodetectors 4015, and two end positions of the sliding plate 401 are detected through the cooperation of the first light-shielding sheets 4014 and the first photodetectors 4015, for example, in fig. 7, when the sliding plate 401 moves to the right end position, the first light-shielding sheets 4014 extend into the first photodetectors 4015, the first photodetectors 4015 detect the first light-shielding sheets 4014, and then send a signal to the circuit board 504, and the circuit board 504 controls the motor 501 to stop rotating, thereby positioning the sliding. In addition, a second shading sheet 4016 is fixedly installed in the middle of the second horizontal plate 4012, a second photoelectric detector 4017 is correspondingly installed on the drive assembly mounting plate 1012, and the second photoelectric detector 4017 is located in the middle of the drive assembly mounting plate 1012; similarly, when the motor 501 drives the sliding plate 401 to move on the sliding rail 403, and when the sliding plate 401 moves to the middle position, the second light shielding piece 4016 extends into the second photodetector 4017, the second photodetector 4017 sends a signal to the circuit board 504, the motor 501 is controlled by the circuit board 504 to stop rotating, and the sliding plate 401 stops at the middle position of the sliding rail 403.
As shown in fig. 8 and 9, for the positioning structure of the sliding plate 401, in addition to fig. 6 and 7, the present invention further provides an embodiment, a fixed hole is disposed in the sliding slot 1011 of the bottom plate 101, the fixed hole is located at the center of the sliding slot 1011 in the length direction, a positioning ball plunger 1013 is mounted in the fixed hole, three alignment grooves 1014 are disposed on the lower surface of the first horizontal plate 4011, and the three alignment grooves 1014 are respectively located at the left end position, the middle position and the right end position of the sliding plate 401; as for the operation of the positioning ball plunger 1013 and the alignment recess 1014, we will further describe, as shown in fig. 7, when the first horizontal plate 4011 of the sliding plate 401 is located at the end position of the right end of the sliding slot 1011, the positioning ball plunger 1013 abuts against the alignment recess 1014 at the left end of the first horizontal plate 4011, when the first horizontal plate 4011 moves leftwards in the sliding slot 1011 and the first horizontal plate 4011 moves to the middle position, the motor 501 is controlled to stop rotating by the action of the second shade 4016 and the second photo detector 4017, and at the same time, the positioning ball plunger 1013 abuts against the alignment recess 1014 at the middle of the first horizontal plate 4011, since the shape of the alignment recess 1014 is exactly matched with the structure of the top of the positioning ball plunger 1013, when the first horizontal plate 4011 moves to the middle position, the position of the first horizontal plate 4011 can be finely adjusted by the cooperation of the positioning plunger 1013 and the alignment recess 1014, the design of the structure can eliminate the defect of inaccurate alignment caused by the light shielding sheet and the photoelectric detector, and improve the positioning precision while controlling the first horizontal plate 4011 to automatically slide in the sliding groove 1011.
In any of the embodiments, the invention proposes a specific embodiment for the optical filter fixing frame 60, as shown in fig. 10 and 11, the optical filter fixing frame 60 is a hollow structure with an open top, and a reflective sheet 601 is disposed inside the optical filter fixing frame 60; the optical filter fixing frame 60 has a bottom surface and a front surface, the front surface is provided with a first optical filter fixing hole 602 communicated with the inside, and a first optical filter is fixed in the first optical filter fixing hole 602; the bottom surface is provided with a second optical filter fixing hole 603 communicated with the inside, a second optical filter is fixed in the second optical filter fixing hole 603, and through holes are formed in the first transverse plate 4011 corresponding to the optical filter fixing frame 60. When the optical filter fixing frame 60 is used, as shown in fig. 1, laser enters from the light inlet 301 of the front panel 30, passes through the first optical filter fixing hole 602, and is filtered by the action of the first optical filter, the filtered laser passes through the top of the optical filter fixing frame 60 by the reflection action of the reflection sheet 601 and is emitted from the light outlet 201 of the cover plate 20, the reaction chamber for performing gene sequencing reaction is located at the light outlet of the cover plate 20, the fluorescent probe inside the reaction chamber emits fluorescence under the excitation action of the laser, because the reflection sheet 601 is made of semitransparent and semi-reflective material, the fluorescence penetrates through the reflection sheet 601, and is captured by the microscope located below the bottom plate 101 after being filtered by the second optical filter, and the fluorescence signal captured by the microscope forms a fluorescence signal graph along with the progress of sequencing reaction.
As to the installation structure of the optical filter fixing frame 60, a specific embodiment is provided in the present invention, as shown in fig. 12 and 13, a first fixing block 701 and a second fixing block 702 are fixed on the first horizontal plate 4011, a guide groove 703 is formed between the first fixing block 701 and the second fixing block 702, and the optical filter fixing frame 60 is fixed in the guide groove 703. Specifically, first fixed block 701 has the first internal surface of laminating mutually with light filter mount 60, and second fixed block 702 has the second internal surface of laminating mutually with light filter mount 60, the contained angle that first internal surface and second internal surface and first diaphragm 4011 were is the acute angle, and, be provided with inclined plane 604 with first internal surface, the laminating of second internal surface mutually on the light filter mount 60, be provided with constant head tank 605 on the inclined plane 604, be provided with a locating pin 704 on the second fixed block 702, and be provided with a spring between locating pin 704 and the second fixed block 702, light filter mount 60 is fixed after in the guide way 703, locating pin 704's top card is gone into constant head tank 605 in. With such a structure, when the optical filter fixing frame 60 is clamped into the guide groove 703, the inclined surfaces 604 on both sides of the optical filter fixing frame 60 are respectively contacted with the first inner surface of the first fixing block 701 and the second inner surface of the second fixing block 702, and meanwhile, the top ends of the positioning pins 704 are clamped into the positioning grooves 605 of the optical filter fixing frame 60, so as to realize the positioning of the optical filter fixing frame 60; because the optical filter and the reflective sheet 601 on the optical filter fixing frame 60 need to be replaced after being used for a period of time, the optical filter fixing frame 60 is convenient to replace due to the structural design of the optical filter fixing frame 60, when the optical filter fixing frame 60 needs to be replaced, the optical filter fixing frame 60 is directly taken out of the guide groove 703, and a new optical filter fixing frame 60 is installed; in addition, the rear end of the filter fixing frame 60 is provided with a chamfer 606, which facilitates the insertion of the filter fixing frame 60 into the guide groove 703.
In the embodiment of fig. 12 and 13, a light blocking plate 705 is further mounted on the second fixed block 702, the light blocking plate 705, the second fixed block 702 and the first horizontal plate 4011 are provided with a through hole 7051, the through hole is communicated with each other, one end of the light blocking plate 705 tilts upward, when the sliding plate 401 moves to the middle position, the tilted end of the light blocking plate 705 blocks the light entrance on the front panel 30, and the microscope can directly observe the sequencing reaction chamber through the light exit on the bottom plate 101 and the light exit on the cover plate 20.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents and improvements made within the spirit and principle of the present invention are intended to be included within the scope of the present invention.

Claims (10)

1. An optical filter switching apparatus, comprising:
the base comprises a bottom plate and a slide rail mounting plate perpendicular to the bottom plate, a sliding groove is formed in the bottom plate, and a positioning ball plunger is mounted in the sliding groove of the bottom plate;
the sliding assembly comprises a sliding plate, a sliding block and a sliding rail, the sliding plate comprises a first transverse plate positioned in the sliding groove and a connecting plate perpendicular to the first transverse plate, the sliding rail is fixed on the sliding rail mounting plate, the sliding block is fixed on the connecting plate, and the sliding block is arranged on the sliding rail in a sliding manner;
the optical filter fixing frames are fixed on the first transverse plate, the optical filter fixing frames are used for installing optical filters and are at least a pair of optical filter fixing frames, a plurality of alignment grooves are formed in the lower surface of the first transverse plate, the first transverse plate slides in the sliding grooves, and the first transverse plate is positioned by abutting a positioning ball plunger piston in the alignment grooves;
and the driving assembly is arranged on the bottom plate and is used for driving the first transverse plate to move in the sliding groove.
2. The filter switching apparatus according to claim 1, wherein: the base further comprises a driving assembly mounting plate, the driving assembly mounting plate is parallel to the bottom plate or is positioned on the same plane, the sliding rail mounting plate is positioned between the bottom plate and the driving assembly mounting plate, and the driving assembly is mounted on the driving assembly mounting plate.
3. The filter switching apparatus according to claim 2, wherein: the sliding plate is Z-shaped and also comprises a second transverse plate vertical to the connecting plate;
the driving assembly comprises a motor, a rotating gear and a rack, the motor is fixed on the driving assembly mounting plate, and the rotating gear is mounted on an output shaft of the motor; the rack is arranged on the second transverse plate and meshed with the rotating gear.
4. A filter switching device according to claim 3, wherein: the optical filter switching device also comprises a front panel and a cover plate;
the base still includes two curb plates that are located bottom plate both ends and perpendicular to bottom plate, the apron is fixed the top of curb plate is provided with relative spacing draw-in groove on two curb plates, the both ends of front panel insert in the spacing draw-in groove of two curb plates, be provided with the light entry on the front panel, be provided with the light export on apron and the bottom plate.
5. The filter switching apparatus according to claim 4, wherein: the two ends of the connecting plate are also fixedly provided with first shading sheets, and the inner walls of the two side plates are correspondingly and respectively provided with a first photoelectric detector;
the middle part fixed mounting of second diaphragm has the second anti-dazzling screen, what correspond on the drive assembly mounting panel installs the second photoelectric detector.
6. The filter switching apparatus according to claim 1, wherein: the optical filter fixing frame is of a hollow structure with an opening at the top, and a reflecting sheet is arranged in the optical filter fixing frame;
the optical filter fixing frame is provided with a bottom surface and a front surface, a first optical filter fixing hole communicated with the interior is formed in the front surface, and a first optical filter is fixed in the first optical filter fixing hole;
and a second optical filter fixing hole communicated with the inside is formed in the bottom surface, and a second optical filter is fixed in the second optical filter fixing hole.
7. The filter switching apparatus according to claim 6, wherein: the optical filter fixing frame is characterized in that a first fixing block and a second fixing block are fixed on the first transverse plate, a guide groove is formed between the first fixing block and the second fixing block, and the optical filter fixing frame is fixed in the guide groove.
8. The filter switching apparatus according to claim 7, wherein: the first fixing block is provided with a first inner surface attached to the optical filter fixing frame, the second fixing block is provided with a second inner surface attached to the optical filter fixing frame, and included angles formed by the first inner surface and the second inner surface and the first transverse plate are acute angles.
9. The filter switching apparatus according to claim 8, wherein: be provided with the inclined plane of laminating mutually with first internal surface, second internal surface on the light filter mount, be provided with the constant head tank on the inclined plane, be provided with a shop bolt on the second fixed block, and be provided with a spring between shop bolt and the second fixed block, the light filter mount is fixed at the guide way after, shop bolt's top card is gone into the constant head tank in.
10. A filter switching device according to any one of claims 7 to 9, wherein: and a light blocking sheet is also arranged on the second fixed block.
CN201611027868.6A 2016-11-17 2016-11-17 Optical filter switching device Active CN108072951B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201611027868.6A CN108072951B (en) 2016-11-17 2016-11-17 Optical filter switching device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201611027868.6A CN108072951B (en) 2016-11-17 2016-11-17 Optical filter switching device

Publications (2)

Publication Number Publication Date
CN108072951A CN108072951A (en) 2018-05-25
CN108072951B true CN108072951B (en) 2020-06-23

Family

ID=62161173

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201611027868.6A Active CN108072951B (en) 2016-11-17 2016-11-17 Optical filter switching device

Country Status (1)

Country Link
CN (1) CN108072951B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109401942A (en) * 2018-12-19 2019-03-01 深圳麦芽加速器科技有限公司 A kind of sequencing optical system
CN112713497B (en) * 2019-10-25 2022-06-14 潍坊华光光电子有限公司 Die strip fixing carrier for semiconductor laser
CN112683798A (en) * 2020-12-14 2021-04-20 长春长光辰谱科技有限公司 Identification and identification system based on hyperspectral imaging camera
CN113398859B (en) * 2021-06-17 2022-05-10 河北化工医药职业技术学院 Light reaction device with filtering structure for organic chemistry experiment
CN114089493B (en) * 2021-11-12 2024-02-02 哈尔滨工业大学 Multi-optical element electric switching device and method with dustproof function

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201637987U (en) * 2010-03-27 2010-11-17 惠州市百宏微动技术工业有限公司 Micro switching filter module
CN102540378A (en) * 2010-12-07 2012-07-04 亚洲光学股份有限公司 Filter switching module for optical projection system
CN202583670U (en) * 2012-04-18 2012-12-05 彭晟罡 Optical filter switching device
CN104698565A (en) * 2015-03-30 2015-06-10 中山联合光电科技股份有限公司 Lens filtering device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201637987U (en) * 2010-03-27 2010-11-17 惠州市百宏微动技术工业有限公司 Micro switching filter module
CN102540378A (en) * 2010-12-07 2012-07-04 亚洲光学股份有限公司 Filter switching module for optical projection system
CN202583670U (en) * 2012-04-18 2012-12-05 彭晟罡 Optical filter switching device
CN104698565A (en) * 2015-03-30 2015-06-10 中山联合光电科技股份有限公司 Lens filtering device

Also Published As

Publication number Publication date
CN108072951A (en) 2018-05-25

Similar Documents

Publication Publication Date Title
CN108072951B (en) Optical filter switching device
US9880407B2 (en) Test fixture for electrical function test of product to be tested
EP1982161A2 (en) Modular fluorimetric or photometric reader
US8968658B2 (en) Luminescence measurement utilizing cartridge with integrated detector
CN113376133A (en) Nucleic acid detector
CN110161007A (en) A kind of optical detection apparatus for the synchronous detection of multi-wavelength fluorescence
CN211402148U (en) Fluorescent tester
CN111215161B (en) Optical detection system for nucleic acid amplification instrument
CN217059933U (en) Cell counting instrument
CN215833255U (en) Nucleic acid detector
CN216285100U (en) Thin-layer plate feeding mechanism and thin-layer chromatography scanner
CN215447798U (en) Printing ink scraper check out test set
CN210775218U (en) Parallel fluorescence detector with different wavelengths
CN117302942A (en) Biochip mobile device
EP3971554A1 (en) Three-dimensional sample scanning system
CN210090306U (en) Fluorescent biochip detector
CN202133646U (en) Fixed wavelength detector
CN219915383U (en) Fluorescence module for fluorescence microscopy equipment and fluorescence microscopy equipment
CN216746709U (en) Stray light analysis device with built-in coaxial telecentric lens
CN217846073U (en) Fluorescence chromatography immunoassay subassembly
CN216560243U (en) Optical detection device for fluorescence detection
CN209859449U (en) Rail mounted uses printing opacity experimental apparatus for physics experiments
CN219285202U (en) Vertical multichannel immunofluorescence instrument
CN211553776U (en) Single-drive lead screw transmission detection device
CN215180246U (en) Full-automatic immunity mark appearance is with multi-functional liquid-transfering device

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant