CN108066679A - A kind of composition of children's skin bacteria inhibitor and preparation method thereof - Google Patents

A kind of composition of children's skin bacteria inhibitor and preparation method thereof Download PDF

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Publication number
CN108066679A
CN108066679A CN201710361540.6A CN201710361540A CN108066679A CN 108066679 A CN108066679 A CN 108066679A CN 201710361540 A CN201710361540 A CN 201710361540A CN 108066679 A CN108066679 A CN 108066679A
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composition
children
bacteria inhibitor
skin bacteria
skin
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CN201710361540.6A
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Inventor
梅荣彬
许世翠
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Anhui Bodhi Biological Medicine Science And Technology Co Ltd
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Anhui Bodhi Biological Medicine Science And Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/86Violaceae (Violet family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/904Stemonaceae (Stemona family), e.g. croomia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
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  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Composition of a kind of children's skin bacteria inhibitor the invention discloses technical field of medicine preparation and preparation method thereof, which is made of with the composition of skin bacteria inhibitor the raw material of following parts by weight:Cinnamomum camphora:7~12g;Honeysuckle:5~10g;The tuber of stemona:3~6g;Folium artemisiae argyi:10~13g;Sculellaria barbata:7~10g;Chinese violet:7~10g;Kuh-seng:5~8g;Wild chrysanthemum:6~8g, S1:Above-mentioned raw materials be heated to 80~100 DEG C into the water boil to carry 3 times, every time 2 it is small when, merge extracting solution, filtering is spare;S2:It adds in the ethanol solution that weight percent concentration is 75%, is settled to 1000ml, stirs evenly afterwards, both finished product is obtained, the present invention is without chemistry and hormonal components, to human body without ill-effect, with it easily and effectively, wide market is suitble to hospital, clinic and sojourns in crowd.

Description

A kind of composition of children's skin bacteria inhibitor and preparation method thereof
Technical field
The present invention relates to technical field of medicine preparation, the specially a kind of composition of children's skin bacteria inhibitor and its preparation Method.
Background technology
Bacterium on skin can be divided into transient and resident bacteria.Resident bacteria is lived under keratoderma epithelial cell Face can also be found in skin surface.Staphylococcus epidermis is its most important species.Other resident bacteria include human-like grape ball Bacterium, coagulase-negative staphylococci, Corynebacterium.Most common skin resident bacterium colony is pityrosporum ovale bacterium in fungi.Resident bacteria There are two major protective functions:Resist external microorganism and nutrition is competed in microecosystem.Usual resident bacteria seldom with infection It is related, but infection can be caused in sterile body cavity, eyes or incomplete skin.Transient bacterium is planted in skin epidermis layer, passes through Commonly wash one's hands and can remove.Transient bacterium is not bred generally on the skin, but they can survive in skin surface and part is bred. Transient bacterium often contacts directly the environmental surfaces for obtaining or contacting near patient by medical staff and patient and pollutes, therefore with Hospital infection is closely related.In our daily life, the common such as merbromin of skin medication, purple mercury, Iodophor are although right Skin plays an important role of that disinfection is antibacterial, since children's skin is more tender and lovely, has pollution to children's clothing using above-mentioned fungicide, together The improper of Shi Gongyong can cause human body to be poisoned, and iodine is a kind of carcinogen, commonly use harmful.For this purpose, it is proposed that A kind of composition of children's skin bacteria inhibitor and preparation method thereof comes into operation, to solve the above problems.
The content of the invention
It is an object of the invention to provide a kind of composition of children's skin bacteria inhibitor and preparation method thereof, in solution Although it is common as merbromin, purple mercury, Iodophor etc. have disinfection antibacterial skin to state the skin medication proposed in background technology Effect, but has clothing pollution, at the same mercury with it is improper human body can be caused to be poisoned, and iodine is a kind of carcinogen, is commonly used pair The problem of human body is harmful to.
To achieve the above object, the present invention provides following technical solution:A kind of composition of children's skin bacteria inhibitor, should Children are made of with the composition of skin bacteria inhibitor the raw material of following parts by weight:
Cinnamomum camphora:7~12g;
Honeysuckle:5~10g;
The tuber of stemona:3~6g;
Folium artemisiae argyi:10~13g;
Sculellaria barbata:7~10g;
Chinese violet:7~10g;
Kuh-seng:5~8g;
Wild chrysanthemum:6~8g.
Preferably, a kind of composition of children's skin bacteria inhibitor, the composition of children's skin bacteria inhibitor is by following The raw material composition of parts by weight:
Cinnamomum camphora:8g;
Honeysuckle:7g;
The tuber of stemona:5g;
Folium artemisiae argyi:10g;
Sculellaria barbata:8g;
Chinese violet:8g;
Kuh-seng:6g;
Wild chrysanthemum:6g.
Preferably, the dosage form of described pharmaceutical composition is external application type water solubility liniment.
Preferably, a kind of preparation method of the composition of children's skin bacteria inhibitor, the group of children's skin bacteria inhibitor The preparation method for closing object is as follows:
S1:Weigh cinnamomum camphora:7~12g, honeysuckle:5~10g, the tuber of stemona:3~6g, folium artemisiae argyi:10~13g, Sculellaria barbata:7~ 10g, Chinese violet:7~10g, kuh-seng:5~8g, wild chrysanthemum:6~8g is heated to 80~100 DEG C and boils to carry 3 into the water afterwards It is secondary, every time 2 it is small when, merge extracting solution, filtering, it is spare;
S2:Solution in step S1 is added in the ethanol water that weight percent concentration is 25%, be settled to 1000ml is stirred evenly afterwards, both obtains finished product.
Preferably, the children are amber transparent liquid with skin bacteria inhibitor composition.
Compared with prior art, the beneficial effects of the invention are as follows:The present invention is free of chemistry and hormonal components, to children invariably Good action, with it easily and effectively, the present invention are water-soluble liniment, and curative effect is rapid and notable, and wide market is suitble to doctor Institute, clinic and household children use.
Specific embodiment
The technical solution in the embodiment of the present invention is clearly and completely described below, it is clear that described embodiment Only part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, the common skill in this field Art personnel all other embodiments obtained without making creative work belong to the model that the present invention protects It encloses.
Embodiment one
A kind of composition of children's skin bacteria inhibitor, the composition of children's skin bacteria inhibitor is by following parts by weight Raw material forms:Cinnamomum camphora:8g, honeysuckle:7g, the tuber of stemona:5g, folium artemisiae argyi:10g, Sculellaria barbata:8g, Chinese violet:8g, kuh-seng:6g, open country Chrysanthemum:6g.
The present invention also provides a kind of preparation method of the composition of children's skin bacteria inhibitor, the children are antibacterial with skin The preparation method of the composition of agent is as follows:
S1:Weigh cinnamomum camphora:8g, honeysuckle:7g, the tuber of stemona:5g, folium artemisiae argyi:10g, Sculellaria barbata:8g, Chinese violet:8g, kuh-seng: 6g, wild chrysanthemum:6g is heated to 80~100 DEG C and boils to carry 3 times into the water afterwards, every time 2 it is small when, merge extracting solution, filtering is standby With;
S2:Solution in step S1 is added in the ethanol water that weight percent concentration is 25%, be settled to 1000ml is stirred evenly afterwards, both obtains finished product.
Embodiment two
A kind of composition of children's skin bacteria inhibitor, the composition of children's skin bacteria inhibitor is by following parts by weight Raw material forms:Cinnamomum camphora:7g, honeysuckle:5g, the tuber of stemona:3g, folium artemisiae argyi:11g, Sculellaria barbata:7g, Chinese violet:7g, kuh-seng:5g, open country Chrysanthemum:7g.
The present invention also provides a kind of preparation method of the composition of children's skin bacteria inhibitor, the children are antibacterial with skin The preparation method of the composition of agent is as follows:
S1:Weigh cinnamomum camphora:7g, honeysuckle:5g, the tuber of stemona:3g, folium artemisiae argyi:11g, Sculellaria barbata:7g, Chinese violet:7g, kuh-seng: 5g, wild chrysanthemum:7g is heated to 80~100 DEG C and boils to carry 3 times into the water afterwards, every time 2 it is small when, merge extracting solution, filtering is standby With;
S2:Solution in step S1 is added in the ethanol water that weight percent concentration is 25%, be settled to 1000ml is stirred evenly afterwards, both obtains finished product.
Embodiment three
A kind of composition of children's skin bacteria inhibitor, the composition of children's skin bacteria inhibitor is by following parts by weight Raw material forms:Cinnamomum camphora:12g, honeysuckle:10g, the tuber of stemona:6g, folium artemisiae argyi:13g, Sculellaria barbata:10g, Chinese violet:10g, kuh-seng: 8g, wild chrysanthemum:8g.
The present invention also provides a kind of preparation method of the composition of children's skin bacteria inhibitor, the children are antibacterial with skin The preparation method of the composition of agent is as follows:
S1:Weigh cinnamomum camphora:12g, honeysuckle:10g, the tuber of stemona:6g, folium artemisiae argyi:13g, Sculellaria barbata:10g, Chinese violet:10g、 Kuh-seng:8g, wild chrysanthemum:8g is heated to 80~100 DEG C and boils to carry 3 times into the water afterwards, every time 2 it is small when, merge extracting solution, mistake Filter, it is spare;
S2:Solution in step S1 is added in the ethanol water that weight percent concentration is 25%, be settled to 1000ml is stirred evenly afterwards, both obtains finished product.
The detailed directions of the present invention:External application, is applied to affected part in right amount, daily 2~3 times, for children because of unknown cause mistake Erythema block caused by quick source is itched, contact skin class, eczema, seborrhea etc., and the present invention is water-soluble class, easy to use, and Curative effect is notable rapidly.
The clinical practice of the present invention:
Typical case one:Dingyuan County Red Hill street, Liu's surname carry out relative, have child at night to cry and scream incessantly, two hands are outside chest It is disorderly grabbed at clothing, household opens in a hurry the clothes of children, finds many places lump not of uniform size, the present invention is taken uniformly to be applied to trouble Place, time in a moment, child wept stop, and symptom disappears, and goes to sleep peacefully.
Typical case two:Fengtai district of Beijing, one granddaughter of Feng family, because of the object that contact is not net accidentally of playing, two hand bifurcations grow more A bubble is smeared with the present invention and wipes affected part, and rear right is smeared once within one hour, and after half a day, bubble disappears, and illing skin is dry and comfortable, and one It fully recovers after it.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with Understanding without departing from the principles and spirit of the present invention can carry out these embodiments a variety of variations, modification, replace And modification, the scope of the present invention is defined by the appended.

Claims (5)

1. a kind of composition of children's skin bacteria inhibitor, it is characterised in that:The composition of children's skin bacteria inhibitor by with The raw material composition of lower parts by weight:
Cinnamomum camphora:7~12g;
Honeysuckle:5~10g;
The tuber of stemona:3~6g;
Folium artemisiae argyi:10~13g;
Sculellaria barbata:7~10g;
Chinese violet:7~10g;
Kuh-seng:5~8g;
Wild chrysanthemum:6~8g.
2. a kind of composition of children's skin bacteria inhibitor according to claim 1, it is characterised in that:Children's skin The composition of bacteriostatic agent is made of the raw material of following parts by weight:
Cinnamomum camphora:8g;
Honeysuckle:7g;
The tuber of stemona:5g;
Folium artemisiae argyi:10g;
Sculellaria barbata:8g;
Chinese violet:8g;
Kuh-seng:6g;
Wild chrysanthemum:6g.
3. a kind of composition of children's skin bacteria inhibitor according to claim 1-2, it is characterised in that:The medicine group The dosage form for closing object is external application type water solubility liniment.
4. a kind of preparation method of the composition of children's skin bacteria inhibitor according to claim 1-3, it is characterised in that: The preparation method of the composition of children's skin bacteria inhibitor is as follows:
S1:Weigh cinnamomum camphora:7~12g, honeysuckle:5~10g, the tuber of stemona:3~6g, folium artemisiae argyi:10~13g, Sculellaria barbata:7~10g, purple Flower Chinese violet:7~10g, kuh-seng:5~8g, wild chrysanthemum:6~8g is heated to 80~100 DEG C and boils to carry 3 times, every time into the water afterwards 2 it is small when, merge extracting solution, filtering, it is spare;
S2:Solution in step S1 is added in the ethanol water that weight percent concentration is 75%, is settled to 1000ml, it After stir evenly, both finished product.
5. a kind of preparation method of the composition of children's skin bacteria inhibitor according to claim 4, it is characterised in that:Institute It is amber transparent liquid that children, which are stated, with skin bacteria inhibitor composition.
CN201710361540.6A 2017-05-22 2017-05-22 A kind of composition of children's skin bacteria inhibitor and preparation method thereof Pending CN108066679A (en)

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Application Number Priority Date Filing Date Title
CN201710361540.6A CN108066679A (en) 2017-05-22 2017-05-22 A kind of composition of children's skin bacteria inhibitor and preparation method thereof

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Publication Number Publication Date
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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1192374A (en) * 1998-03-30 1998-09-09 林湘群 Spray for preventing and treating moist tinea
KR100311199B1 (en) * 1996-07-12 2001-12-15 성재갑 Composition having antimicrobial activity for propionibacterium acnes and inhibition activity for 5alpha-reductase
CN1565575A (en) * 2003-06-27 2005-01-19 左会生 Medicinal liquor for preventing and treating skin disease of hands and feet and its preparing process
CN101181429A (en) * 2007-12-03 2008-05-21 陕西省万寿制药有限责任公司 Externally used medicament for curing dermatosis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100311199B1 (en) * 1996-07-12 2001-12-15 성재갑 Composition having antimicrobial activity for propionibacterium acnes and inhibition activity for 5alpha-reductase
CN1192374A (en) * 1998-03-30 1998-09-09 林湘群 Spray for preventing and treating moist tinea
CN1565575A (en) * 2003-06-27 2005-01-19 左会生 Medicinal liquor for preventing and treating skin disease of hands and feet and its preparing process
CN101181429A (en) * 2007-12-03 2008-05-21 陕西省万寿制药有限责任公司 Externally used medicament for curing dermatosis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
胡小勤、黄丽萍: "《学做药酒不生病》", 31 January 2014, 西安交通大学出版社 *

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