CN108041184A - A kind of compound lard for preventing and treating angiocardiopathy - Google Patents

A kind of compound lard for preventing and treating angiocardiopathy Download PDF

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Publication number
CN108041184A
CN108041184A CN201711382276.0A CN201711382276A CN108041184A CN 108041184 A CN108041184 A CN 108041184A CN 201711382276 A CN201711382276 A CN 201711382276A CN 108041184 A CN108041184 A CN 108041184A
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oil
parts
epa
dha
weight
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朱坤福
祝蕾
苏姗姗
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Shandong Zhushi Pharmaceutical Group Co Ltd
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Shandong Zhushi Pharmaceutical Group Co Ltd
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00Other edible oils or fats, e.g. shortenings, cooking oils
    • A23D9/007Other edible oils or fats, e.g. shortenings, cooking oils characterised by ingredients other than fatty acid triglycerides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00Other edible oils or fats, e.g. shortenings, cooking oils
    • A23D9/02Other edible oils or fats, e.g. shortenings, cooking oils characterised by the production or working-up
    • A23D9/04Working-up

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  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The invention discloses a kind of compound lards for preventing and treating angiocardiopathy, in parts by weight, are made of following raw material:0.4 ~ 0.6 part of 1 ~ 10 part of fish oil, 1 ~ 10 part of perilla herb oil, 1 ~ 10 part of granada seed oil, 12 ~ 80 parts of vegetative grease, 0.9 ~ 1.5 part of stabilizer and odor additive;The weight ratio of EPA and DHA is 6 ~ 9 in the fish oil:1, and the weight of EPA and DHA and in fish oil proportion be 50 ~ 95%;The effect of compound lard prevention and treatment angiocardiopathy of the present invention, is notable, pass through the allotment of science, contain EPA, flavones, oryzanol, sterol, punicic acid, VE, phytosterol etc., there is good curative effect to cardiovascular and cerebrovascular, fat metabolism can be adjusted, artery sclerosis is prevented, blood cholesterol levels, blood viscosity is reduced, inhibits platelet aggregation, improve blood circulation;Low-density albumen can be reduced, increasing high density lipoprotein recovers blood vessel elasticity, increase coronary blood flow, prevention and the effect of prevention artery sclerosis and hypertension, thus reach prevention and/or treatment angiocardiopathy, especially treat the purpose of coronary heart disease and hypertension.

Description

A kind of compound lard for preventing and treating angiocardiopathy
Technical field
The present invention relates to compound lard technical field, specifically a kind of miscella for preventing and treating angiocardiopathy Fat.
Background technology
As the improvement of people's living standards, the healthcare function of edible oil and fat is increasingly valued by people, related meals The intake of aliphatic acid in food, the World Health Organization and FAO (Food and Agriculture Organization of the United Nation) suggest, saturated fat in the grease of human consumption Acid, monounsaturated fatty acids and polyunsaturated fatty acid ratio should be balances, be advisable with following ratio, specifically, saturation Aliphatic acid:Monounsaturated fatty acids:Polyunsaturated fatty acid=1:1:1, fats nutrient animals and plants edible oil is to be related to often The health problem of a family at present due to the irrationality of people's dietary structure, causes more and more rich people's diseases to generate, common Such as hypertension, hyperlipidemia, hyperglycaemia, high blood is sticky, obesity, diabetes, fatty liver and the cardiovascular and cerebrovascular as caused by blood Disease etc.;But existing compound lard is generally reached using the simply allotment of conventional vegetable oil, it is necessary to add functional materials Specific trophic function, polyunsaturated fatty acid absorptivity in vivo and conversion ratio are low, and the stability of grease is poor, easily rise Bubble, and smell is poor.
In addition, also there are the unscientific situations of EPA and DHA weight ratios for existing compound lard, it is impossible to meet kinsfolk The physiological requirements of middle different edible object, because EPA is metabolizable into prostacyclin in human body, and then body work( Can, such as the EPA of children taking excess, there is the possibility for promoting sex premature, and have inhibition to children's intelligence and skeleton development; And DHA is easy to enter brain cell by brain barrier, is present in brain cell and brain cell protrusion, causes neural excessively emerging Put forth energy, thus EPA and DHA proportioning it is unreasonable can to some crowd's healths generate deleterious effect.
CN 200810235299.3 discloses a kind of ready-mixed oil with hypolipemic function, but wherein ω -6 and ω -3 Weight ratio is 4-6:1, saturated fatty acid is no more than 15%, but its balanced fatty acid is still not reasonable, so being not reaching to good Hypolipemic function.CN1942180A also discloses that essential fatty acid is preventing and/or treating coronary heart disease or arterial disease patient Application in depression, wherein also referring to the ethyl ester type eicosapentaenoic acid with high concentration(EPA)And docosahexaenoic acid (DHA)Application of the mixture in coronary heart disease or cardiovascular patient, but the ratio of wherein EPA and DHA is 0.9:1.5, it should Ratio far can not meet the needs of some diseases.
The content of the invention
To solve the above problems, the object of the present invention is to provide a kind of compound lards for preventing and treating angiocardiopathy.
The present invention to achieve the above object, is achieved through the following technical solutions:
A kind of compound lard for preventing and treating angiocardiopathy, in parts by weight, is made of following raw material:1 ~ 10 part of fish oil, 1 ~ 10 part of perilla herb oil, 1 ~ 10 part of granada seed oil, 12 ~ 80 parts of vegetative grease, 0.9 ~ 1.5 part of stabilizer and odor additive 0.4 ~ 0.6 part;
The weight ratio of EPA and DHA is 6 ~ 9 in the fish oil:1, and the weight of EPA and DHA and proportion is in fish oil 50~95%;
The vegetative grease is Seabuckthorm Seed Oil, evening primrose oil, linseed oil, sunflower oil, safflower seed oil, olive oil, grape Three kinds or four kinds in seed oil, palm oil, samara oil, camellia oil, rice bran oil, peony seed oil and medium chain triglyceride;
The stabilizer is two or three in green-tea extract, astaxanthin, lycopene and VE;
The odor additive is vanillic aldehyde, ethylmaltol, eugenol, anethole, peppermint oil, Fructus Monordicae extract, lemon Two or three in oil and orange oil.
Preferably, the vegetative grease is safflower seed oil, Seabuckthorm Seed Oil, linseed oil, evening primrose oil and grape seed oil In three kinds or four kinds.
Preferably, the odor additive is in eugenol, anethole, peppermint oil, Fructus Monordicae extract and lemon oil Three kinds.
Preferably, the weight ratio of EPA and DHA is 7 ~ 8 in the fish oil:1, and the weight of EPA and DHA and in fish oil Proportion is 80 ~ 95%.
Preferably, the stabilizer by green-tea extract and lycopene according to mass ratio 1:1 ratio is mixed to get.
Preferably, in parts by weight, it is made of following raw material:5 ~ 10 parts of fish oil, 1 ~ 5 part of perilla herb oil, granada seed oil 1 ~ 5 Part, 30 ~ 50 parts of safflower seed oil, 1 ~ 10 part of Seabuckthorm Seed Oil, 1 ~ 10 part of linseed oil, 0.5 part of vitamin E, 0.4 part of astaxanthin, perfume 0.1 part of blue 0.1 part of element, 0.1 part of ethylmaltol, 0.1 part of lemon oil and orange oil;
The weight ratio of EPA and DHA is 7 ~ 8 in the fish oil:1, and the weight of EPA and DHA and proportion is in fish oil 70~95%。
Preferably, in parts by weight, it is made of following raw material:5 ~ 10 parts of fish oil, 1 ~ 5 part of perilla herb oil, granada seed oil 1 ~ 5 Part, 10 ~ 30 parts of safflower seed oil, 1 ~ 10 part of linseed oil, 1 ~ 10 part of evening primrose oil, 0.7 part of green-tea extract, lycopene 0.7 0.2 part of part, 0.2 part of vanillic aldehyde, 0.1 part of eugenol and Fructus Monordicae extract;In the fish oil weight ratio of EPA and DHA for 7 ~ 8:1, and the weight of EPA and DHA and in fish oil proportion be 70 ~ 95%.
Preferably, in parts by weight, it is made of following raw material:5 ~ 10 parts of fish oil, 1 ~ 5 part of perilla herb oil, granada seed oil 1 ~ 5 Part, 10 ~ 30 parts of grape seed oil, 10 ~ 20 parts of Seabuckthorm Seed Oil, 1 ~ 10 part of linseed oil, 1 ~ 10 part of evening primrose oil, 0.6 part of astaxanthin, 0.2 part of 0.4 part of lycopene, 0.5 part of vitamin E, 0.2 part of Peppermint essential oil, 0.2 part of lemon and sweet orange oil;The fish The weight ratio of EPA and DHA is 7 ~ 8 in oil:1, and the weight of EPA and DHA and in fish oil proportion be 70 ~ 95%.
It is further preferred that it in parts by weight, is made of following raw material:8 parts of fish oil, 3 parts of perilla herb oil, 4 parts of granada seed oil, 20 parts of safflower seed oil, 5 parts of linseed oil, 5 parts of evening primrose oil, 0.7 part of green-tea extract, 0.7 part of lycopene, vanillic aldehyde 0.2 Part, 0.2 part of 0.1 part of eugenol and Fructus Monordicae extract;The weight ratio of EPA and DHA is 7 in the fish oil:1, and EPA and The weight of DHA and in fish oil proportion be 90%.
It is further preferred that it in parts by weight, is made of following raw material:8 parts of fish oil, 4 parts of perilla herb oil, 3 parts of granada seed oil, 25 parts of grape seed oil, 15 parts of Seabuckthorm Seed Oil, 5 parts of linseed oil, 5 parts of evening primrose oil, 0.6 part of astaxanthin, 0.4 part of lycopene, 0.2 part of 0.5 part of vitamin E, 0.2 part of Peppermint essential oil, 0.2 part of lemon and sweet orange oil;EPA and DHA in the fish oil Weight ratio is 7:1, and the weight of EPA and DHA and in fish oil proportion be 90%.
Above-mentioned grease is placed in agitator tank, 30 ~ 40 DEG C, N210 are stirred with the rotating speed of 10 ~ 25r/min under protection ~ 30min makes uniformly, it is filling to be cooled to room temperature sealing, you can.
The present invention has the following advantages compared with prior art:
The effect of compound lard prevention and treatment angiocardiopathy of the present invention, is notable, by the allotment of science, contains EPA, Huang The ratio of ketone, oryzanol, sterol, punicic acid, VE, phytosterol etc., wherein unrighted acid is 70 ~ 90%, how unsaturated fat The ratio of ω -6 and ω -3 is 0.5 ~ 1.5 in fat acid:1, there is good curative effect to cardiovascular and cerebrovascular, fat metabolism can be adjusted, prevent Artery sclerosis is controlled, blood cholesterol levels, blood viscosity is reduced, inhibits platelet aggregation, improve blood circulation;Low-density egg can be reduced In vain, increasing high density lipoprotein recovers blood vessel elasticity, increases coronary blood flow, prevention and prevention artery sclerosis and high blood The effect of pressure, thus reach prevention and/or treatment angiocardiopathy, especially treat the purpose of coronary heart disease and hypertension;
The compound lard of the prevention and treatment angiocardiopathy of the present invention, by the proportioning compound lard of each component The ratio of ω -6 and ω -3 reaches 0.5 ~ 1.5:1, the ratio of unrighted acid is 70 ~ 90%;And the ω -3 in fish oil Ratio account for 50 ~ 80% of ω -3 ratios in compound lard, the selection of fish oil of the present invention can ensure the ratio of three kinds of aliphatic acid Example, i.e. saturated fatty acid:Monounsaturated fatty acids:Polyunsaturated fatty acid=1:1:1, and contained by EPA in fish oil and DHA Amount is limited in the range of science, avoids the inaccuracy of magnitude of recruitment, the relatively low or higher phenomenon of appearance, because if there are relatively low feelings Condition cannot meet the physiological requirements of human body, and then because of the unsaturation in its structure and double bond peroxidization can occur for excess intake, Generate lipid peroxide, cause aging and occur canceration because the rise of lipid peroxide than cholesterol rise to artery congee Sample hardens the harm bigger to form generation;
It is poor that the compound lard of the prevention and treatment angiocardiopathy of the present invention solves existing fish oil stability, is only used for protecting The problem of being good for product market and not being suitable in edible oil makes us not pleasant fish by adding in the odor additive improvement present invention The characteristic odor of oily distinctive fishlike smell and other greases, the steady of compound lard is improved by using specific stabilizer It is qualitative, it shields, cold and dressed with sauce can not only eat to active ingredient, and can also keep mixing in the stewed eating method of frying The stability of grease makes it that can retain maximum useful constituent in the culinary art heating process of family, and in good taste, can quilt Consumer receives.
Specific embodiment
Below in conjunction with specific embodiment, the invention will be further described.
Embodiment 1
A kind of compound lard for preventing and treating angiocardiopathy, is made of following raw material:1 part of fish oil, 1 part of perilla herb oil, pomegranate 1 part of seed oil, 1 part of Seabuckthorm Seed Oil, 3 parts of evening primrose oil, 8 parts of linseed oil, 0.1 part of green-tea extract, 0.8 part of astaxanthin, chinese cymbidium 0.3 part of 0.1 part of element and ethylmaltol;
The weight ratio of EPA and DHA is 6 in the fish oil:1, and the weight of EPA and DHA and proportion is in fish oil 50%。
Embodiment 2
A kind of compound lard for preventing and treating angiocardiopathy, is made of following raw material:10 parts of fish oil, 10 parts of perilla herb oil, stone 10 parts of pomegranate seed oil, 4 parts of sunflower oil, 5 parts of safflower seed oil, 3 parts of olive oil, 0.8 part and VE0.7 parts of lycopene, eugenol 0.2 0.4 part of part and anethole;
The weight ratio of EPA and DHA is 9 in the fish oil:1, and the weight of EPA and DHA and proportion is in fish oil 95%。
Embodiment 3
A kind of compound lard for preventing and treating angiocardiopathy, is made of following raw material:1 part of fish oil, 1 part of perilla herb oil, pomegranate 10 parts of seed oil, 10 parts of grape seed oil, 10 parts of palm oil, 60 parts of samara oil, 0.1 part of green-tea extract, 0.9 part of lycopene are thin 0.2 part of 0.3 part of lotus oil and Fructus Monordicae extract;
The weight ratio of EPA and DHA is 7 in the fish oil:1, and the weight of EPA and DHA and proportion is in fish oil 60%。
Embodiment 4
A kind of compound lard for preventing and treating angiocardiopathy, is made of following raw material:2 parts of fish oil, 9 parts of perilla herb oil, pomegranate 0.5 part of 4 parts of seed oil, 50 parts of vegetative grease, 0.6 part of stabilizer and odor additive;
The weight ratio of EPA and DHA is 8 in the fish oil:1, and the weight of EPA and DHA and proportion is in fish oil 70%;
The vegetative grease is camellia oil, rice bran oil, peony seed oil and medium chain triglyceride according to weight ratio 10:10:15:15 Composition;
The stabilizer is astaxanthin and VE according to weight ratio 1:5 compositions;
The odor additive is lemon oil and orange oil according to weight ratio 4:1 composition.
Embodiment 5
A kind of compound lard for preventing and treating angiocardiopathy, is made of following raw material:9 parts of fish oil, 2 parts of perilla herb oil, pomegranate 0.4 part of 2 parts of seed oil, 75 parts of vegetative grease, 1.1 parts of stabilizer and odor additive;
The weight ratio of EPA and DHA is 6.5 in the fish oil:1, and the weight of EPA and DHA and proportion is in fish oil 80%;
The vegetative grease is by Seabuckthorm Seed Oil, linseed oil, safflower seed oil and grape seed oil according to mass ratio 10:25:20:20 Composition;
The stabilizer is by green-tea extract, astaxanthin and lycopene according to mass ratio 5:5:1 composition;
The odor additive is by vanillic aldehyde, eugenol, peppermint oil according to mass ratio 1:1:2 compositions.
Embodiment 6
A kind of compound lard for preventing and treating angiocardiopathy, is made of following raw material:5 parts of fish oil, 6 parts of perilla herb oil, pomegranate 0.6 part of 4 parts of seed oil, 20 parts of vegetative grease, 1.2 parts of stabilizer and odor additive;
The weight ratio of EPA and DHA is 8 in the fish oil:1, and the weight of EPA and DHA and proportion is in fish oil 90%;
The vegetative grease is by evening primrose oil, olive oil, samara oil and rice bran oil according to mass ratio 1:1:1:1 composition;
The stabilizer is by astaxanthin, lycopene and VE according to mass ratio 1:1:1 composition;
The odor additive is by ethylmaltol, lemon oil and orange oil according to mass ratio 1:1:1 composition.
Embodiment 7
A kind of compound lard for preventing and treating angiocardiopathy, is made of following raw material:7 parts of fish oil, 3 parts of perilla herb oil, pomegranate 0.4 part of 4 parts of seed oil, 65 parts of vegetative grease, 1.3 parts of stabilizer and odor additive;
The weight ratio of EPA and DHA is 8 in the fish oil:1, and the weight of EPA and DHA and proportion is in fish oil 85%;
The vegetative grease is by sunflower oil, palm oil, camellia oil and peony seed oil according to mass ratio 20:10:25:10 groups Into;
The stabilizer is by green-tea extract, lycopene and VE according to mass ratio 1:9:3 compositions;
The odor additive is by anethole, Fructus Monordicae extract and orange oil according to mass ratio 1:2:1 composition.
Embodiment 8
A kind of compound lard for preventing and treating angiocardiopathy, is made of following raw material:5 parts of fish oil, 6 parts of perilla herb oil, pomegranate 0.6 part of 8 parts of seed oil, 15 parts of vegetative grease, 1.4 parts of stabilizer and odor additive;
The weight ratio of EPA and DHA is 7 in the fish oil:1, and the weight of EPA and DHA and proportion is in fish oil 80%;
The vegetative grease is by safflower seed oil, Seabuckthorm Seed Oil and linseed oil according to mass ratio 5:4:6 compositions;
The stabilizer is by green-tea extract and lycopene according to mass ratio 3:4 compositions;
The odor additive is eugenol, anethole and peppermint oil according to mass ratio 2:1:3 compositions.
Embodiment 9
A kind of compound lard for preventing and treating angiocardiopathy, is made of following raw material:10 parts of fish oil, 5 parts of perilla herb oil, pomegranate 0.5 part of 4 parts of seed oil, 55 parts of vegetative grease, 1.2 parts of stabilizer and odor additive;
The weight ratio of EPA and DHA is 8 in the fish oil:1, and the weight of EPA and DHA and proportion is in fish oil 95%;
The vegetative grease is by linseed oil, evening primrose oil and grape seed oil according to mass ratio 10:10:35 compositions;
The stabilizer is by astaxanthin and VE according to mass ratio 1:1 composition;
The odor additive is by peppermint oil, Fructus Monordicae extract and lemon oil according to mass ratio 2:1:2 compositions.
Embodiment 10
A kind of compound lard for preventing and treating angiocardiopathy, is made of following raw material:5 parts of fish oil, 1 part of perilla herb oil, pomegranate 1 part of seed oil, 30 parts of safflower seed oil, 1 part of Seabuckthorm Seed Oil, 1 part of linseed oil, 0.5 part of vitamin E, 0.4 part of astaxanthin, vanillic aldehyde 0.1 part, 0.1 part of ethylmaltol, 0.1 part of 0.1 part of lemon oil and orange oil;
The weight ratio of EPA and DHA is 7 in the fish oil:1, and the weight of EPA and DHA and proportion is in fish oil 70%。
Embodiment 11
A kind of compound lard for preventing and treating angiocardiopathy, is made of following raw material:10 parts of fish oil, 5 parts of perilla herb oil, pomegranate 5 parts of seed oil, 50 parts of safflower seed oil, 10 parts of Seabuckthorm Seed Oil, 10 parts of linseed oil, 0.5 part of vitamin E, 0.4 part of astaxanthin, chinese cymbidium 0.1 part of 0.1 part of element, 0.1 part of ethylmaltol, 0.1 part of lemon oil and orange oil;
The weight ratio of EPA and DHA is 8 in the fish oil:1, and the weight of EPA and DHA and proportion is in fish oil 95%。
Embodiment 12
A kind of compound lard for preventing and treating angiocardiopathy, is made of following raw material:7 parts of fish oil, 2 parts of perilla herb oil, pomegranate 4 parts of seed oil, 35 parts of safflower seed oil, 8 parts of Seabuckthorm Seed Oil, 6 parts of linseed oil, 0.5 part of vitamin E, 0.4 part of astaxanthin, vanillic aldehyde 0.1 part, 0.1 part of ethylmaltol, 0.1 part of 0.1 part of lemon oil and orange oil;
The weight ratio of EPA and DHA is 7.5 in the fish oil:1, and the weight of EPA and DHA and proportion is in fish oil 85%。
Embodiment 13
A kind of compound lard for preventing and treating angiocardiopathy, is made of following raw material:5 parts of fish oil, 1 part of perilla herb oil, pomegranate 1 part of seed oil, 10 parts of safflower seed oil, 1 part of linseed oil, 1 part of evening primrose oil, 0.7 part of green-tea extract, 0.7 part of lycopene are fragrant 0.2 part of blue 0.2 part of element, 0.1 part of eugenol and Fructus Monordicae extract;The weight ratio of EPA and DHA is 7 in the fish oil:1, and The weight of EPA and DHA and in fish oil proportion be 70%.
Embodiment 14
A kind of compound lard for preventing and treating angiocardiopathy, is made of following raw material:10 parts of fish oil, 5 parts of perilla herb oil, pomegranate 5 parts of seed oil, 30 parts of safflower seed oil, 10 parts of linseed oil, 10 parts of evening primrose oil, 0.7 part of green-tea extract, 0.7 part of lycopene, 0.2 part of 0.2 part of vanillic aldehyde, 0.1 part of eugenol and Fructus Monordicae extract;The weight ratio of EPA and DHA is 8 in the fish oil:1, and And the weight of EPA and DHA and in fish oil proportion be 95%.
Embodiment 15
A kind of compound lard for preventing and treating angiocardiopathy, is made of following raw material:8 parts of fish oil, 3 parts of perilla herb oil, pomegranate 4 parts of seed oil, 20 parts of safflower seed oil, 5 parts of linseed oil, 5 parts of evening primrose oil, 0.7 part of green-tea extract, 0.7 part of lycopene are fragrant 0.2 part of blue 0.2 part of element, 0.1 part of eugenol and Fructus Monordicae extract;The weight ratio of EPA and DHA is 7 in the fish oil:1, and The weight of EPA and DHA and in fish oil proportion be 90%.
Embodiment 16
A kind of compound lard for preventing and treating angiocardiopathy, is made of following raw material:5 parts of fish oil, 1 part of perilla herb oil, pomegranate 1 part of seed oil, 10 parts of grape seed oil, 10 parts of Seabuckthorm Seed Oil, 1 part of linseed oil, 1 part of evening primrose oil, 0.6 part of astaxanthin, tomato red 0.2 part of 0.4 part of element, 0.5 part of vitamin E, 0.2 part of Peppermint essential oil, 0.2 part of lemon and sweet orange oil;In the fish oil The weight ratio of EPA and DHA is 7:1, and the weight of EPA and DHA and in fish oil proportion be 70%.
Embodiment 17
A kind of compound lard for preventing and treating angiocardiopathy, is made of following raw material:10 parts of fish oil, 5 parts of perilla herb oil, pomegranate 5 parts of seed oil, 30 parts of grape seed oil, 20 parts of Seabuckthorm Seed Oil, 10 parts of linseed oil, 10 parts of evening primrose oil, 0.6 part of astaxanthin, tomato 0.2 part of 0.4 part of red pigment, 0.5 part of vitamin E, 0.2 part of Peppermint essential oil, 0.2 part of lemon and sweet orange oil;In the fish oil The weight ratio of EPA and DHA is 8:1, and the weight of EPA and DHA and in fish oil proportion be 95%.
Embodiment 18
A kind of compound lard for preventing and treating angiocardiopathy, is made of following raw material:8 parts of fish oil, 4 parts of perilla herb oil, pomegranate 3 parts of seed oil, 25 parts of grape seed oil, 15 parts of Seabuckthorm Seed Oil, 5 parts of linseed oil, 5 parts of evening primrose oil, 0.6 part of astaxanthin, tomato red 0.2 part of 0.4 part of element, 0.5 part of vitamin E, 0.2 part of Peppermint essential oil, 0.2 part of lemon and sweet orange oil;In the fish oil The weight ratio of EPA and DHA is 7:1, and the weight of EPA and DHA and in fish oil proportion be 90%.
Influence experiment of the compound lard of the prevention and treatment angiocardiopathy of the present invention to Hypertensive Rats:
The prevention of 1,3,7,8,10,13,15,16 and 18 gained of embodiment is randomly selected in the embodiment of embodiment 1 ~ 18 and is controlled The compound lard for treating angiocardiopathy is tested, while sets control group.
240 160-180g male SD rats(SPF grades)After adaptability is fed, random selection 20 is only used as normal group, gives Give the normal diet containing 12% soybean oil;Remaining 220 is only given high glucose and high fat feed and gradient drinks and prepares hypertension model. It after modeling 3 weeks, is grouped with blood pressure data, chooses 200 successful Hypertensive Rats of modeling, be randomly divided into control group and reality Test group, every group 20.Remaining 20 successful Hypertensive Rats of modeling is as model group, for detecting Hypertensive Rats before nursing Thromboxane B2 in blood plasma(TXB2), prostaglandin(PGI2), NO it is horizontal.
Control group gives normal diet, and experimental group-x gives compound lard feed, and wherein x corresponds to the sequence number of embodiment, real The compound lard feed of group-x is tested compared with normal diet, only the source of grease is different, and grease is provided by embodiment x.After modeling Control group and experimental group give the corresponding systolic pressure fed 4 weeks, measure each group rat weekly according to above-mentioned requirements respectively, final to survey It is horizontal to measure TXB2, PGI2, NO in each group rat plasma.All data are represented with Mean ± SD, soft using Minitab 17.1.0 Part carry out one-way analysis of variance, further with Turkey Multiple range tests determine each group of data between significant difference, notable water It is flat to be set as p< 0.05.
Systolic pressure variation after the rat nursing of different groups weekly is shown in Table 1.
Systolic pressure variation table after the rat nursing of the different groups of table 1 weekly
After modeling First week Second week 3rd week 4th week
Normal group 118.23±7.56a 116.19±2.78a 117.12±8.35a 115.96±9.56a 118.29±5.63a
Experimental group -1 184.16±8.23a 175.98±5.63a 154.23±5.89b 140.32±5.63c 125.68±2.45d
Experimental group -3 183.25±4.97a 174.68±6.13a 147.23±5.14b 141.32±6.23c 124.68±3.78d
Experimental group -7 184.15±6.24a 175.89±5.43a 154.14±5.84b 140.22±5.25c 125.45±3.35d
Experimental group -8 183.85±5.07a 174.75±6.23a 147.34±4.04b 141.40±5.25c 124.73±3.48d
Experimental group -10 184.06±6.53a 170.08±5.63a 149.24±5.29b 134.34±5.43c 120.68±3.46d
Experimental group -13 183.85±4.07a 169.68±5.53a 139.23±4.94b 131.32±5.43c 119.08±3.58d
Experimental group -15 184.12±5.23a 169.88±4.61a 139.45±4.86b 135.02±4.43c 121.12±3.48d
Experimental group -16 183.28±5.27a 164.62±5.43a 137.23±4.74b 131.35±6.40c 118.08±2.75d
Experimental group -18 184.27±8.03a 165.48±4.83a 139.23±5.68b 132.35±5.48c 118.18±3.46d
Control group 186.13±9.13a 185.76±6.98a 182.23±5.36a 178.56±5.42a 168.98±5.28b
Note:Represent that significant difference is notable with a line difference lowercase a-d(p < 0.05)
As shown in Table 1, compared with before nursing, experimental group rat feeds systolic pressure after two weeks and significantly reduces(p < 0.05), And continuously decreased with the extension of nursing time, it is normal group nearly to feed the crimping of after-contraction in 4 weeks;And the systolic pressure of control group is being fed Just start to reduce after 4 weeks.It can be seen that compound lard can significantly reduce the blood pressure of Hypertensive Rats, have apparent Antihypertensive functional.
TXB in blood plasma after the rat of different groups is fed 4 weeks2、PGI2, NO variations it is as shown in table 2.
TXB2, PGI2, NO variation table in blood plasma after the rat of the different groups of table 2 is fed
After modeling First week Second week
Normal group 64.89±2.37a 13.56±4.32a 39.17±4.13a
Model group 78.63±2.59b 9.56±2.56b 18.46±2.98b
Experimental group -1 65.32±3.59a 12.58±2.14a 37.99±3.45c
Experimental group -3 63.29±5.19a 11.85±4.56a 37.56±3.75c
Experimental group -7 64.92±3.45a 12.95±2.44a 37.84±3.65c
Experimental group -8 63.49±5.12a 11.89±5.66a 36.68±3.54c
Experimental group -10 65.38±3.45a 12.86±2.38a 36.55±3.46c
Experimental group -13 64.12±4.16a 12.05±4.48a 36.82±3.48c
Experimental group -15 64.89±3.55a 12.28±3.24a 36.12±3.05c
Experimental group -16 63.49±5.14a 11.94±4.45a 36.45±3.25c
Experimental group -18 64.54±3.48a 12.85±2.36a 36.56±3.25c
Control group 76.23±4.21b 10.59±4.13b 23.57±1.98d
As shown in Table 2, compared with after modeling success, the TXB2 of experimental group rat is significantly raised, with normal group without significant difference; PGI2 and NO are significantly reduced, and PGI2 is horizontal and normal group without significant difference.So compound lard can be intravascular by protecting Chrotoplast, balance blood vessel endothelium relax the contracting factor, and then improvement arterial dilation, reach antihypertensive function.
Taste appraisal
Mouth is carried out to the compound lard of the prevention and treatment angiocardiopathy of 1,3,7,8,10,13,15,16 and 18 gained of embodiment Taste is evaluated, while sets control group, odor additive is not added in control group, remaining ingredient is identical, and evaluation result is converged Always, the results are shown in Table 3.
3 compound lard taste appraisal result of table
Appraiser A Appraiser B Appraiser C
Embodiment 1 There is light fragrance Savory, taste is pleasant It is savory, it can receive
Embodiment 1- Control With heavier fishlike smell, smell It is difficult to receive With heavier fishlike smell Fishlike smell is heavier
Embodiment 3 There is mint flavored, taste pleasure There is mint flavored and sweet taste Savory, taste is pleasant
Embodiment 3- Control There is heavier fishlike smell With heavier fishlike smell, it is mingled with Light green tea taste Fishlike smell is heavier
Embodiment 7 It is distinctive with sweet orange, green tea etc. Fragrance Light sweet taste with sweet orange There is sweet taste
Embodiment 7- Control With heavier fishlike smell, it is mingled with Light green tea taste There is heavier fishlike smell There are heavier fishlike smell, taste It is unpleasant
Embodiment 8 Fragrance with peppermint and cloves With peppermint, the fragrance of cloves With peppermint, the fragrance of cloves, Also there is green tea fragrance
Embodiment 8- Control There is heavier fishlike smell There is heavier fishlike smell, taste is difficult It hears Fishlike smell is heavier
Embodiment 10 It is distinctive with sweet orange, lemon etc. Fragrance taste Fragrance with lemon, taste order People is pleasant, Fruit aroma can receive
Embodiment 10- is compareed Fishlike smell weight Heavier fishlike smell Fishlike smell weight
Embodiment 13 Fragrance with cloves It is savory, there are some sweet tastes There is the taste of sweet tea sweet tea
Embodiment 13- is compareed Grease and the taste of fish Fishlike smell, it is difficult to receive Fishlike smell is heavier
Embodiment 15 There is the fragrance of cloves It is savory, there are some sweet tastes There is the taste of sweet tea sweet tea
Embodiment 15- is compareed Grease and the taste of fish Fishlike smell, it is difficult to receive Fishlike smell is heavier
Embodiment 16 There is the mixed flavor of peppermint and lemon There is the mixing of peppermint and lemon perfume Taste, it is more pleasant There is the mixing of peppermint and lemon perfume Taste, it is more pleasant
Embodiment 16- is compareed Fishlike smell is heavier Fishlike smell is heavier, it is difficult to receive Heavier fishy smell
Embodiment 18 There is the mixing of peppermint and lemon perfume Taste, it is more pleasant There is the mixed flavor of peppermint and lemon There is the mixing of peppermint and lemon perfume Taste, it is more pleasant
Embodiment 18- is compareed Fishlike smell is heavier Fishlike smell is heavier, it is difficult to receive Heavier fishy smell
By the evaluation result of table 3, it can be improved by adding taste modifying ingredients and make us not pleasant fish in the present invention The characteristic odor of oily distinctive fishlike smell and other greases is esthetically acceptable to the consumers the taste of the present invention.
Estimation of stability, while setting pair are carried out to the fat or oil composition of embodiment 1,3,7,8,10,13,15,16 and 18 According to group --- the inoxidizability ingredient in embodiment is not added(Green-tea extract, astaxanthin, lycopene, VE), remaining ingredient It is identical.The stability of fat or oil composition is evaluated using accelerated oxidation experiment.More than fat or oil composition and control group is each 100g is respectively placed in wide-mouth bottle, while is placed in 60 DEG C of constant temperature oven and is carried out accelerated oxidation, every the separately sampled references of 2d The peroxide value of GB 5009.227-2016 determination samples.What sample peroxide value changed over time the results are shown in Table 4.
4 sample oxidation value of table changes with time result table
As shown in Table 4, under identical accelerated oxidation experiment condition, the peroxide of embodiment 1,3,7,8,10,13,15,16 and 18 The trend that change value changes over time is identical, the 12d before placement, and peroxide value is as the extension of standing time is almost without change Change, be slightly increased in 14d and 16d, about increased by 1 times at the 16th day.And control group peroxide value from being placed 4d drastically increases Add, in 10d, peroxide value has added more than ten times, and implementation group, in 16 days of placement, the color of sample is almost Do not change, be buff;And control group starts color burn phenomenon occur placing 6d, in 10d, color is almost For black, there is serious grease rancidity.
It can be seen that the antioxidant content added in the present invention(Green-tea extract, in astaxanthin, lycopene and VE Two or more)The stability of fat or oil composition can be increased, prevent the variation of the taste and color generated due to Oxidation of Fat and Oils.

Claims (10)

1. a kind of compound lard for preventing and treating angiocardiopathy, it is characterised in that:In parts by weight, by following raw material group Into:1 ~ 10 part of fish oil, 1 ~ 10 part of perilla herb oil, 1 ~ 10 part of granada seed oil, 12 ~ 80 parts of vegetative grease, 0.9 ~ 1.5 part of stabilizer and 0.4 ~ 0.6 part of odor additive;
The weight ratio of EPA and DHA is 6 ~ 9 in the fish oil:1, and the weight of EPA and DHA and proportion is in fish oil 50~95%;
The vegetative grease is Seabuckthorm Seed Oil, evening primrose oil, linseed oil, sunflower oil, safflower seed oil, olive oil, grape Three kinds or four kinds in seed oil, palm oil, samara oil, camellia oil, rice bran oil, peony seed oil and medium chain triglyceride;
The stabilizer is two or three in green-tea extract, astaxanthin, lycopene and VE;
The odor additive is vanillic aldehyde, ethylmaltol, eugenol, anethole, peppermint oil, Fructus Monordicae extract, lemon Two or three in oil and orange oil.
2. a kind of compound lard for preventing and treating angiocardiopathy according to claim 1, it is characterised in that:The plant Physical property grease is three kinds or four kinds in safflower seed oil, Seabuckthorm Seed Oil, linseed oil, evening primrose oil and grape seed oil.
3. a kind of compound lard for preventing and treating angiocardiopathy according to claim 1, it is characterised in that:The perfume (or spice) Taste additive is three kinds in eugenol, anethole, peppermint oil, Fructus Monordicae extract and lemon oil.
4. a kind of compound lard for preventing and treating angiocardiopathy according to claim 1, it is characterised in that:It is described The weight ratio of EPA and DHA is 7 ~ 8 in fish oil:1, and the weight of EPA and DHA and in fish oil proportion be 80 ~ 95%.
5. a kind of compound lard for preventing and treating angiocardiopathy according to claim 1, it is characterised in that:It is described steady Agent is determined by green-tea extract and lycopene according to mass ratio 1:1 ratio is mixed to get.
6. a kind of compound lard for preventing and treating angiocardiopathy according to claim 1, it is characterised in that:With weight Part meter, is made of following raw material:5 ~ 10 parts of fish oil, 1 ~ 5 part of perilla herb oil, 1 ~ 5 part of granada seed oil, 30 ~ 50 parts of safflower seed oil, sea-buckthorn 1 ~ 10 part of seed oil, 1 ~ 10 part of linseed oil, 0.5 part of vitamin E, 0.4 part of astaxanthin, 0.1 part of vanillic aldehyde, ethylmaltol 0.1 Part, 0.1 part of 0.1 part of lemon oil and orange oil;
The weight ratio of EPA and DHA is 7 ~ 8 in the fish oil:1, and the weight of EPA and DHA and proportion is in fish oil 70~95%。
7. a kind of compound lard for preventing and treating angiocardiopathy according to claim 1, it is characterised in that:With weight Part meter, is made of following raw material:5 ~ 10 parts of fish oil, 1 ~ 5 part of perilla herb oil, 1 ~ 5 part of granada seed oil, 10 ~ 30 parts of safflower seed oil, flax 1 ~ 10 part of seed oil, 1 ~ 10 part of evening primrose oil, 0.7 part of green-tea extract, 0.7 part of lycopene, 0.2 part of vanillic aldehyde, eugenol 0.1 0.2 part of part and Fructus Monordicae extract;The weight ratio of EPA and DHA is 7 ~ 8 in the fish oil:1, and the weight of EPA and DHA and Proportion is 70 ~ 95% in fish oil.
8. a kind of compound lard for preventing and treating angiocardiopathy according to claim 1, it is characterised in that:With weight Part meter, is made of following raw material:5 ~ 10 parts of fish oil, 1 ~ 5 part of perilla herb oil, 1 ~ 5 part of granada seed oil, 10 ~ 30 parts of grape seed oil, sea-buckthorn 10 ~ 20 parts of seed oil, 1 ~ 10 part of linseed oil, 1 ~ 10 part of evening primrose oil, 0.6 part of astaxanthin, 0.4 part of lycopene, vitamin E 0.5 part, 0.2 part of Peppermint essential oil, 0.2 part of 0.2 part of lemon and sweet orange oil;The weight ratio of EPA and DHA is in the fish oil 7~8:1, and the weight of EPA and DHA and in fish oil proportion be 70 ~ 95%.
9. a kind of compound lard for preventing and treating angiocardiopathy according to claim 7, it is characterised in that:With weight Part meter, is made of following raw material:8 parts of fish oil, 3 parts of perilla herb oil, 4 parts of granada seed oil, 20 parts of safflower seed oil, 5 parts of linseed oil, the moon See careless 5 parts of oil, 0.7 part of green-tea extract, 0.7 part of lycopene, 0.2 part of vanillic aldehyde, 0.1 part of eugenol and Fructus Monordicae extract 0.2 part;The weight ratio of EPA and DHA is 7 in the fish oil:1, and the weight of EPA and DHA and proportion is in fish oil 90%。
10. a kind of compound lard for preventing and treating angiocardiopathy according to claim 8, it is characterised in that:With weight Part meter is measured, is made of following raw material:8 parts of fish oil, 4 parts of perilla herb oil, 3 parts of granada seed oil, 25 parts of grape seed oil, Seabuckthorm Seed Oil 15 Part, 5 parts of linseed oil, 5 parts of evening primrose oil, 0.6 part of astaxanthin, 0.4 part of lycopene, 0.5 part of vitamin E, Peppermint essential oil 0.2 part, 0.2 part of 0.2 part of lemon and sweet orange oil;The weight ratio of EPA and DHA is 7 in the fish oil:1, and EPA and The weight of DHA and in fish oil proportion be 90%.
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Application publication date: 20180518