CN108029694A - A kind of bactericidal composition containing nitrile pyrrole mite ester and fluazinam - Google Patents
A kind of bactericidal composition containing nitrile pyrrole mite ester and fluazinam Download PDFInfo
- Publication number
- CN108029694A CN108029694A CN201711439324.5A CN201711439324A CN108029694A CN 108029694 A CN108029694 A CN 108029694A CN 201711439324 A CN201711439324 A CN 201711439324A CN 108029694 A CN108029694 A CN 108029694A
- Authority
- CN
- China
- Prior art keywords
- fluazinam
- mite ester
- nitrile pyrrole
- pyrrole mite
- bactericidal composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
Abstract
The present invention relates to a kind of bactericidal composition containing nitrile pyrrole mite ester and fluazinam, its active ingredient is nitrile pyrrole mite ester and fluazinam binary built.Wherein the mass ratio of nitrile pyrrole mite ester and fluazinam is 1~50: 50~1, the quality parts ratio 1%~80% of active ingredient nitrile pyrrole mite ester and fluazinam in preparation, remaining is the auxiliary element for allowing to use and receiving in pesticide, and the formulation of bactericidal composition of the present invention is missible oil, suspending agent, wettable powder, aqua, water dispersible granules, aqueous emulsion, microemulsion, granule, microcapsule formulations.It is suitable for the various powdery mildews of the ornamental plants such as fruit tree, vegetables, flowers, field crop.
Description
Technical field
The present invention relates to technical field of pesticide combination, more particularly to a kind of sterilization group containing nitrile pyrrole mite ester and fluazinam
Compound.
Background technology
Nitrile pyrrole mite ester is new in the novel pyrazoles acaricide released in 2009, the pharmacy effect mechanism by Nissan Chemical
Grain husk, the insecticidal/acaricidal agent with using now do not have cross resistance, available for all kinds of on the crops such as prevention fruit tree, tealeaves and vegetables
Evil mite.
Fluazinam (SHIRLAN, test code number B-1216, IKF-1216, ICIA0912, the chloro- N- of 3- (the chloro- 5- fluoroforms of 3-
Base -2- pyridine radicals)-α, fluoro- 2, the 6- dinitros-p-toluidine of α, α-three) it is that industry development is originated in by Japanese stone, by ICI
The pyridyl amine fungicide of Agrochemicals (being now Syngenta Co., Ltd) exploitations.Fluazinam has the bactericidal activity of wide spectrum, to epidemic disease
Mildew, rotten sclerotiniose, black spot, scab and other pathogen diseases have good prevention effect.Specific disease such as cucumber
Gray mold, rot disease, downy mildew, charcoal seasonal febrile diseases, powdery mildew, stem's rot disease, tomato late blight, scab of apple, leaf spot, pears
Black spot, rust, rice blast, banded sclerotial blight, crown hull sugar, grape grey mould, downy mildew, citrus scab, gray mold,
The late blight of potato, lawn spot disease.
It is the maximally efficient means of controlling plant diseases using chemical agent.But apply single long-term continuous high dose
Chemical bactericide, be easy to cause the problems such as residual of medicament, environmental pollution and resistance to resistance to the action of a drug fungi are developed.Rational chemistry
Bactericide compounded or mixture have expand fungicidal spectrum, improve prevention effect, extend the optimum period for applying fertilizer, reduce dosage, reduce poisoning,
Reduce residual, delay the positive feature such as Antifungal resistance and drug-fast generation and development, bactericide compounded is to solve above-mentioned ask
One of maximally efficient method of topic.Develop new product fungicide price is constantly soaring, and in contrast, exploitation with research efficiently,
Low toxicity, the compounding of low-residual and mixture have small investment, the lead time is short and is paid attention to both at home and abroad, and numerous and confused increase develops
Dynamics.We screen and on the basis of field trial, filter out nitrile pyrrole mite ester and compounded with fluazinam indoors, have obvious
Synergistic effect.And people there is no to report at present on the bactericidal composition and application of nitrile pyrrole mite ester and the compounding of fluazinam.
The content of the invention
Based on case above, present invention aims at provide a kind of new and effective pesticide sterilizing composite.It is mainly used for
The ornamental plants such as fruit tree, vegetables, flowers, the various powdery mildews of field crop.
Technical solution of the present invention is realized by following measures：
A kind of bactericidal composition containing nitrile pyrrole mite ester and fluazinam, the active ingredient nitrile pyrrole mite ester of the bactericidal composition with
Fluazinam two-spot compounds, remaining is auxiliary element.Active ingredient nitrile pyrrole mite ester and fluazinam in wherein described bactericidal composition
Mass ratio is 1~50: 50~1, and the bactericidal composition of the present invention is through toxicity test experimental verification, nitrile pyrrole mite ester and fluazinam
Mass ratio be 1~10: 10~1 when, synergistic effect is preferable.
The formulations of pesticide that the bactericidal composition of the present invention can be prepared are missible oil, suspending agent, wettable powder, water
Agent, water dispersible granules, aqueous emulsion, microemulsion, granule, microcapsule formulations.Wherein active ingredient nitrile pyrrole mite ester is being made with fluazinam
Gross mass in agent accounts for the 1%~80% of the whole quality of the pharmaceutical preparations, wherein when accounting for 10%~60%, toxicity and residual reach preferable
Balance, cost are relatively low.
The specific embodiment for the formulations of pesticide that bactericidal composition of the present invention is configured to is as follows：
The bactericidal composition is cream preparation, and the mass fraction of component is：1~50 part of nitrile pyrrole mite ester；Fluazinam 1~
50 parts；10~30 parts of conventional emulsifier；20~50 parts of Conventional solvents；Conventional 1~5 part of synergist.The specific life of the cream preparation
Production step for first by active ingredient nitrile pyrrole mite ester and fluazinam addition solvent in be completely dissolved after add emulsifying agent, synergist stirs
It is filling, you can the cream preparation of the present composition is made into the oily liquids of transparent and homogeneous after mixing uniformly.
The bactericidal composition is suspending agent, and the mass fraction of component is：1~50 part of nitrile pyrrole mite ester；Fluazinam 1~50
Part；5~20 parts of dispersant；1~5 part of antifreezing agent；0.1~2 part of thickener；0.1~0.8 part of defoamer；0~10 part of penetrating agent；
0.1~5 part of pH adjusting agent；Water, surplus.Other auxiliary agents is first are mixed by the specific production stage of the suspending agent, through cutting at a high speed
Cut uniformly mixed, add active ingredient nitrile pyrrole mite ester and fluazinam, when abrading-ball 2~3 is small in ball crusher, a diameter is existed
Below 5mm, you can the aqueous suspension formulations of the present composition are made.
The bactericidal composition is wettable powder, and the mass fraction of component is：1~50 part of nitrile pyrrole mite ester；Fluazinam 1
~50 parts；3~10 parts of dispersant；1~5 part of wetting agent；Filler, surplus.The specific production stage of the wettable powder is：By upper
State formula to mix active ingredient nitrile pyrrole mite ester with fluazinam and dispersant, wetting agent and filler, uniformly stirred in stirred tank
Mix, be uniformly mixed after airslide disintegrating mill, you can the wettable powder of the present composition is made.
The bactericidal composition is water dispersible granules, and the mass fraction of component is：1~50 part of nitrile pyrrole mite ester；Fluazinam 1
~50 parts；3~10 parts of dispersant；1~10 part of wetting agent；1~5 part of disintegrant；Filler, surplus.The water dispersible granules it is specific
Production stage is：By above-mentioned formula by active ingredient nitrile pyrrole mite ester and fluazinam and dispersant, wetting agent, disintegrant and filler
It is uniformly mixed, is crushed with micro jet, through mediating, be then granulated, dried in addition fluidized-bed granulation dryer,
Through sampling analysis after screening, you can the water dispersible granules of the present composition are made.
The bactericidal composition is aqueous emulsion, and the mass fraction of component is：1~50 part of nitrile pyrrole mite ester；Fluazinam 1~50
Part；3~30 parts of emulsifying agent；5~15 parts of solvent；2~15 parts of stabilizer；1~5 part of antifreezing agent；0.1~8 part of defoamer；Thickener
0.2~2 part；Water, surplus.The specific production stage of the aqueous emulsion is：First by nitrile pyrrole mite ester and fluazinam, solvent and emulsification
Agent, cosolvent are added together, and make to be dissolved into uniform oil phase；Other pesticides such as part water, antifreeze, antimicrobial are helped
Agent mixes into uniform water phase；In a kettle while high-speed stirred by oil phase add water phase, slowly plus water until
Reach phase inversion point, open cutter and carry out high speed shear, and add remaining water, shearing about half an hour, form oil-in-water type
Aqueous emulsion, you can the aqueous emulsion of the present composition is made.
The bactericidal composition is microemulsion, and the mass fraction of component is：1~50 part of nitrile pyrrole mite ester；Fluazinam 1~50
Part；10~30 parts of emulsifying agent, 1~8 part of antifreezing agent, 0.5~10 part of stabilizer, 20~50 parts of Conventional solvents cosolvent.By nitrile pyrrole
Mite ester is completely dissolved with fluazinam with cosolvent, adds the other compositions such as emulsifying agent, antifreezing agent stabilizer, uniformly mixing, most
After add water, microemulsion can be made into after being sufficiently stirred.
The bactericidal composition is granule, and the mass fraction of component is：1~50 part of nitrile pyrrole mite ester；Fluazinam 1~50
Part；1~10 part of wetting dispersing agent；0.1~5 part of thickener；0.1~5 part of defoamer；Castor oil, surplus are supplied.By active ingredient
The each component such as nitrile pyrrole mite ester and fluazinam, dispersant, stabilizer, defoamer and solvent is mixed in the ratio of formula, is put into sand milling
In kettle after grinding, it is sent into mixing in mixer for well-distribution and gets product.
The bactericidal composition is aqua, and the mass fraction of component is：1~50 part of nitrile pyrrole mite ester；Fluazinam 1~50
Part；0.1~30 part of wetting dispersing agent；2~8 parts of antifreezing agent；0.1~1 part of defoamer；0.1~3 part of thickener；Spreader-sticker 5~15
Part；Water, surplus are supplied.Active ingredient nitrile pyrrole mite ester is completely dissolved with fluazinam, with cosolvent, adds dispersant, antifreeze
The other compositions such as agent, defoamer, uniformly mixing, is eventually adding water, after being sufficiently stirred, you can obtains finished product.
The bactericidal composition is microcapsule formulations, and the mass fraction of component is：1~50 part of nitrile pyrrole mite ester；Fluazinam 1~
50 parts；5~20 parts of urea；5~20 parts of formaldehyde；5~20 parts of emulsifying dispersant；1~5 part of antifreezing agent；0.1~2 part of thickener；Disappear
0.1~0.8 part of infusion；Water, surplus.(the amount ratio of material is about for addition urea and formaldehyde in the three-necked flask equipped with agitating device
For l：1.5~2.0) pH value of solution, is adjusted with sodium hydroxide solution to 8~9 or so, then heats to 70~80 DEG C, reaction
Obtain stable urea resin prepolymer.Take a certain amount of nitrile pyrrole mite ester to be dissolved in fluazinam in hexamethylene, and add in the solution
Enter emulsifying dispersant, with being vigorously stirred, be made into the O/W type stable emulsions using the aqueous solution containing emulsifying dispersant as water phase.Will
Above-mentioned urea resin prepolymer is added in lotion, adjusts pH value, polymerisation occurs under acid catalysed conditions, makes oil phase substance
It is wrapped, forms microcapsule granule.Slowly heating, cures, and temperature control is at 40~50 DEG C, hardening time 1h.Selection adds
Enter suitable auxiliary agent, you can the microcapsules that must stablize.
Wherein above-described emulsifying agent is selected from calcium dodecyl benzene sulfonate and aliphatic acid polyethenoxy ether, alkyl phenol polyoxy
Ethene ether sulfosuccinates, styrylphenol polyoxyethylene ether, nonylphenol polyoxyethylene ether, castor oil polyoxyethylene ether,
Any one of aliphatic acid polyethenoxy base ester, polyoxyethylene aliphatic alcohol ether or more than one any mixtures than composition.
The solvent is dimethylbenzene or biodiesel, toluene, diesel oil, methanol, ethanol, n-butanol, isopropanol, rosin-based
Vegetable oil code name is ND-45, solvent naphtha, dimethylformamide, dimethyl sulfoxide (DMSO), and the one or more in water equal solvent are appointed
Anticipate than the mixture of composition.
The dispersant is LG-3, GY-D1252, GY-D1256, SNWGF-01 selected from polycarboxylate code name, lignin
Sulfonate code name is 201107,201108, alkylphenol polyoxyethylene ether methyl ether condensate sulfate, alkylsulfonate calcium salt, naphthalene
Sulfonic formaldehyde condensation compound sodium salt, alkylphenol polyoxyethylene ether, polyoxyethylene carboxylate, aliphatic amine polyoxyethylene ether, glyceride
One or more of fat acid ester polyoxyethylene ether.
The wetting agent is selected from lauryl sodium sulfate, and calcium dodecyl benzene sulfonate, Nekal BX, moistens bleeding agent F,
Alkylbenzenesulfonate polyoxyethylene triphen phosphenylic acid salt dimly, spaonin powder, silkworm excrement, the one or more in spaonin powder.
The disintegrant is selected from bentonite, urea, ammonium sulfate, aluminium chloride, citric acid, succinic acid, in sodium acid carbonate
It is one or more.
The thickener is selected from xanthans, carboxymethyl cellulose, carboxyethyl cellulose, methylcellulose, Magnesiumaluminumsilicate,
It is one or more in polyvinyl alcohol.
The stabilizer is selected from sodium citrate, one kind in resorcinol.
The antifreezing agent is selected from ethylene glycol, propane diols, the one or more in glycerine.
The defoamer is selected from silicone oil, silicone compound, C10-20Saturated fat acids compound, C8-10Fatty alcohol
It is one or more.
The filler is selected from kaolin, diatomite, bentonite, attapulgite, white carbon, starch, in precipitated calcium carbonate
One or more.
The present invention has obvious synergistic effect using nitrile pyrrole mite ester and composite bactericide of the fluazinam as active ingredient, delays
The drug-fast generation in key, and reduce into production cost and use cost, be mainly used for the ornamental plants such as fruit tree, vegetables, flowers,
The various powdery mildews of field crop.
Embodiment
To make technical scheme, purpose and advantage are more clearly understood, present invention specific examples below
Illustrate, but the present invention is not limited to these examples.The effect experiment of the present invention uses indoor biometrics and field trial phase
With reference to mode, unless otherwise instructed, ratio mentioned below is all quality parts ratio.
Embodiment：Nitrile pyrrole mite ester is tested with fluazinam different ratio co-toxicity.
1.1 reagent agent
96% fluazinam active compound, 95% nitrile pyrrole mite ester active compound, above-mentioned active compound are ground by extra large Lear medicine company limited company
Hair portion provides.
1.2 experiment targets
Wheat powdery mildew germ, isolates and purifies gained, in PDA from the wheat powdery mildew incidence of leaf that Fengyang County is taken back
Preserved on inclined-plane in 4 DEG C of refrigerator cultures.
For trying culture medium:
PDA culture medium:Potato 200g, glucose 20g, agar 20g, water 1000ml.
AEA culture mediums:Dusty yeast 5g/L, glycerine 20mL/L, MgSO40.25g/L, NaNO36g/L, KCl 0.5g/L,
KH2PO41.5g/L, agar powder 20g/L, deionized water 1L.
1.3 test method
1.3.1 medicament is prepared
Acetone solution active compound is first used, suitable two active compound is made into by several different ratios according to the result of preliminary experiment,
It is stand-by that each processing is diluted to several concentration gradients respectively with acetone again.
By susceptible wheat cultivation in pot for growing seedlings, it is placed in greenhouse and cultivates, plant grows to three to after four leaf stage, and collection is identical
The blade of leaf age, culture and measure for wheat powdery mildew.
1.3.2 the culture of wheat powdery mildew and the preparation of spore suspension
Wheat powdery mildew is cultivated using plants method under conditions of 20 DEG C, 12h alternation of light and darkness, turns to be commissioned to train per 30d
Support 1 time.With the conidium on sterile water elution incidence of leaf during inoculation, it is l × 10 to be configured to spore concentration6A/mL's is outstanding
Supernatant liquid.
1.3.3 strains tested sensitivity testing
Toxicity test is carried out using leaf dish moisturizing method.The blade of collection is first prepared into the leaf dish of a diameter of 1.5cm, at random
Mix, be respectively placed in the series concentration liquid configured and soak lh, each 50 leaf dishes of concentration, are tested with the place of not adding medicine
Manage as blank control, after immersion, leaf is face-up placed on the blotting paper of identical liquor strength wetting, in leaf dish
Liquid blot, by prepared spore suspension l0L be inoculated in leaf dish center, room temperature place 5min after, be placed in 20 DEG C, 12h
Cultivated under conditions of alternation of light and darkness, the onset area in leaf dish is measured after 10d, calculates EC50。
The sick level of percentage division of leaf dish area is accounted for according to lesion area
0 grade：It is disease-free；
1 grade：Sorus area accounts for less than the 5% of whole leaf area；
3 grades：Sorus area accounts for below the 6%-10% of whole leaf area；
5 grades：Sorus area accounts for below the 11%-20% of whole leaf area；
7 grades：Sorus area accounts for below the 21%-50% of whole leaf area；
9 grades：Sorus area accounts for more than the 50% of whole leaf area；
1.3.4 mixture toxicity test and interpretation of result
The toxicity test of mixture is carried out according to mixed ratio with single dose toxicity test method.
If compare the death rate<5%, do not correct, the control death rate is corrected between 5%-20% by formula 2, is compareed
The death rate>20%, experiment need to reform.
Using drug concentration (mg/L) to numerical value as independent variable x, using the niqueMin of corrected mortality as dependent variable y, respectively
Virulence regression equation is established, the EC of single dose and each proportioning mixture is calculated using DPS softwares50Poison altogether is calculated according to the abundant methods of Sun Yun
Coefficient (CTC).Co-toxicity coefficient CTC, calculation formula are as follows：(using nitrile pyrrole mite ester as standard agent, 100) its toxicity index is：
The EC of the toxicity index (TI) of fluazinam=nitrile pyrrole mite ester50The EC of/fluazinam50×100
The EC of the true toxicity index (ATI) of M=nitrile pyrrole mite ester50The EC of/M50×100
TI × P fluazinams of TI × P nitrile pyrrole mites ester+fluazinam of the theoretical toxicity index (TTI) of M=nitrile pyrrole mite ester
TTI × 100 of the ATI/M of co-toxicity coefficient (CTC)=M of M
In formula：
M is the mixture of nitrile pyrrole mite ester and fluazinam different ratio
P nitrile pyrrole mites ester is nitrile pyrrole mite ester ratio shared in mixture
P fluazinams are fluazinam ratio shared in mixture.
2.1 toxicity test results
Toxicity test of 1 fluazinam of table with nitrile pyrrole mite ester to wheat powdery mildew
As can be seen from the table, the result of the test of different proportion proportioning shows, dilutes equal table respectively in active ingredient ratio
Reveal stronger synergistic effect, wherein using nitrile pyrrole mite ester and fluazinam as 1:10~10:Synergistic effect is good when 1 suggests to suitable
Preferably match 1:10~10:1 or so mixture preparation carries out further field control effectiveness test, to evaluate its field practical application effect
Fruit.
3rd, field trial prevention wheat powdery mildew, the experimental result of powdery mildew of cucumber
3.1 field trials prevent wheat powdery mildew
3.1.1 test method
Test site is wheat for studying thing, kind is short morning 781, is broadcasted sowing, growing way in Fengyang County capital town great Tong Qiao villages
Preferably, experiment is set sets control totally 10 processing per acre.Often processing is repeated 4 times, random district's groups arrangement, 30 square metres of plot area.
3.1.2 control time and number
Before dispenser, after the 1st medicine 10 days, 20 days after 10 days and the 2nd dispenser, per cell using 5 points of samplings of diagonal,
Every is investigated 20 plants, and 2 leaves are taken from upper end for every plant before blooming, and every plant of Post flowering takes 2 leaf of sword-like leave, and investigation morbidity journey is classified by leaf
Degree, calculating disease refers to and prevention effect.
Grade scale is as follows：
0 grade：It is disease-free；
1 grade：Lesion area accounts for less than the 5% of full wafer leaf area；
3 grades：Lesion area accounts for the 6%-15% of full wafer leaf area；
5 grades：Lesion area accounts for the 16%-25% of full wafer leaf area；
7 grades：Lesion area accounts for the 26%-50% of full wafer leaf area；
9 grades：Lesion area accounts for more than the 50% of full wafer leaf area.
3.1.3 drug effect computational methods
Sick leaf rate (the %)=disease number of sheets/investigation total number of sheets × 100
Disease index=∑ (the disease numbers of sheets at different levels × opposite value of series)/(investigation total number of sheets × 9) × 100
Prevention effect (%)=(1- (disease index after disease index × treatment region medicine before blank district medicine)/(blank pair
According to disease index before disease index after area's medicine × treatment region medicine)) × 100.
3.1.4 poisoning investigation method
Whether continuous 20d range estimations medicament has poisoning to crop after dispenser.
3.1.5 result of the test and analysis
The effect of each processing prevention wheat powdery mildew.(table 2)
Control positive effect of the 30% nitrile pyrrole mite ester fluazinam composite bactericide for wheat powdery mildew as shown in Table 2 is higher than
Nitrile pyrrole mite ester and fluazinam single dose, bactericidal effect are incremented by with the increase of dosage.Estimated according to field, in test dose scope
Interior, plant growth is normal, and each treatment agent does not occur the poisoning phenomenon to wheat, and it is safe to wheat to illustrate it.It is recommended that
The fungicide different from the mechanism of action is used in mixed way to delay the drug-fast generation of germ.
3.2 field trials prevent powdery mildew of cucumber
3.2.1 test method
Test site is cucumber for examination vegetables in the Pingdu herbary of Shandong, and growing way is preferable, and experiment is set sets control altogether per acre
10 processing.Often processing is repeated 4 times, random district's groups arrangement, 14 square metres of plot area.
3.2.2 control time and number
Before dispenser, after the 1st medicine 10 days, 20 days after 10 days and the 2nd dispenser, per cell using 5 points of samplings of diagonal,
Every is investigated 2 plants, totally 10 plants, investigates complete stool blade, is classified investigation occurring degree by leaf, calculating disease refers to and prevention effect.
Grade scale is as follows：
0 grade：It is disease-free；
1 grade：Lesion area accounts for less than the 5% of full wafer leaf area；
3 grades：Lesion area accounts for the 6%-15% of full wafer leaf area；
5 grades：Lesion area accounts for the 16%-25% of full wafer leaf area；
7 grades：Lesion area accounts for the 26%-50% of full wafer leaf area；
9 grades：Lesion area accounts for more than the 50% of full wafer leaf area.
3.2.3 drug effect computational methods
Sick leaf rate (the %)=disease number of sheets/investigation total number of sheets × 100
Disease index=∑ (the disease numbers of sheets at different levels × opposite value of series)/(investigation total number of sheets × 9) × 100
Prevention effect (%)=(1- (disease index after disease index × treatment region medicine before blank district medicine)/(blank pair
According to disease index before disease index after area's medicine × treatment region medicine)) × 100.
3.2.4 poisoning investigation method
Whether continuous 20d range estimations medicament has poisoning to crop after dispenser.
3.2.5 result of the test and analysis
The effect of each processing prevention powdery mildew of cucumber.(table 3)
The Mixed Pharmacy of different proportion as can be seen from Table 3, is tested by different dosages, 30% nitrile pyrrole mite ester
Fluazinam composite bactericide its to prevention be superior to comparison medicament and bactericidal effect with the increase of dosage and be incremented by.According to field
Range estimation, in the range of test dose, plant growth is normal, and each treatment agent does not occur the poisoning phenomenon to cucumber, illustrates it
It is safe to cucumber.It is recommended that the fungicide different from the mechanism of action is used in mixed way to delay the drug-fast generation of germ.
In conclusion the bactericidal composition of the invention containing nitrile pyrrole mite ester and fluazinam, to wheat powdery mildew, cucumber white powder
Disease has good prevention effect, and it is safe to Target crops.Complex preparation not only increases preventive effect, and expands sterilization
Spectrum, widens use scope, reduces cost, plays the role of that a medicine is simultaneous to be controlled to multiple diseases, mitigates manpower and materials, improves production effect
Benefit.So the invention of this complex preparation is of great significance society's tool with promoting.
Claims (4)
- A kind of 1. bactericidal composition containing nitrile pyrrole mite ester and fluazinam, it is characterised in that：The active ingredient of the bactericidal composition For nitrile pyrrole mite ester and fluazinam binary built, remaining is auxiliary element, wherein the quality of active ingredient nitrile pyrrole mite ester and fluazinam Than for 1~50: 50~1.
- 2. bactericidal composition according to claim 1, it is characterised in that：Nitrile pyrrole mite ester and the gross weight of fluazinam in the formulation Amount accounts for the 1%~80% of the whole quality of the pharmaceutical preparations.
- 3. bactericidal composition according to claim 2, it is characterised in that：Nitrile pyrrole mite ester and the gross weight of fluazinam in the formulation Amount accounts for the 5%~60% of the whole quality of the pharmaceutical preparations.
- 4. according to the bactericidal composition described in claim 1 or 2 or 3, it is characterised in that：The formulation of the bactericidal composition is breast Oil, suspending agent, aqua, wettable powder, water dispersible granules, aqueous emulsion, microemulsion, granule, microcapsule formulations.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711439324.5A CN108029694A (en) | 2017-12-27 | 2017-12-27 | A kind of bactericidal composition containing nitrile pyrrole mite ester and fluazinam |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711439324.5A CN108029694A (en) | 2017-12-27 | 2017-12-27 | A kind of bactericidal composition containing nitrile pyrrole mite ester and fluazinam |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108029694A true CN108029694A (en) | 2018-05-15 |
Family
ID=62101429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711439324.5A Withdrawn CN108029694A (en) | 2017-12-27 | 2017-12-27 | A kind of bactericidal composition containing nitrile pyrrole mite ester and fluazinam |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108029694A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109744241A (en) * | 2018-12-28 | 2019-05-14 | 京博农化科技有限公司 | A kind of miticide composition of containing fluazinam and nitrile pyrrole mite rouge |
| CN110269064A (en) * | 2018-03-13 | 2019-09-24 | 江苏扬农化工股份有限公司 | A kind of miticide composition of fluazinam and nitrile pyrrole mite ester compounding |
| CN114431237A (en) * | 2020-11-03 | 2022-05-06 | 浙江省化工研究院有限公司 | Pesticide composition |
-
2017
- 2017-12-27 CN CN201711439324.5A patent/CN108029694A/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110269064A (en) * | 2018-03-13 | 2019-09-24 | 江苏扬农化工股份有限公司 | A kind of miticide composition of fluazinam and nitrile pyrrole mite ester compounding |
| CN109744241A (en) * | 2018-12-28 | 2019-05-14 | 京博农化科技有限公司 | A kind of miticide composition of containing fluazinam and nitrile pyrrole mite rouge |
| CN114431237A (en) * | 2020-11-03 | 2022-05-06 | 浙江省化工研究院有限公司 | Pesticide composition |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105409963A (en) | Sterilization composition containing efficient metalaxyl-M and azoxystrobin | |
| CN108029694A (en) | A kind of bactericidal composition containing nitrile pyrrole mite ester and fluazinam | |
| CN103975932B (en) | A kind of bactericidal composition containing prothioconazoles and flumorph | |
| CN103355308A (en) | Sterilization composition containing prothioconazole and boscalid | |
| CN105409976A (en) | Sterilization composition containing efficient metalaxyl-M and flumorph | |
| CN107980792A (en) | A kind of bactericidal composition containing pyraclostrobin Yu imidazole quinoline copper | |
| CN103931623A (en) | Bactericidal composition containing meptyldinocap and prothioconazole | |
| CN104054709A (en) | Bactericidal composition containing meptyldinocap and fluazinam | |
| CN104054708A (en) | Bactericidal composition containing meptyldinocap and spiroxamine | |
| CN103975928A (en) | Bactericidal composition containing meptyldinocap and penconazole | |
| CN107980785A (en) | A kind of bactericidal composition containing benzo alkene fluorine bacterium azoles and fludioxonil | |
| CN103931640A (en) | Bactericidal composition containing meptyldinocap and pyraclostrobin | |
| CN108605950A (en) | A kind of bactericidal composition containing amisulbrom and hymexazol | |
| CN103503879A (en) | Sterilization composition containing prothioconazole and bupirimate | |
| CN105076166A (en) | Bactericidal composition containing tetramycin and thifluzamide | |
| CN108029690A (en) | A kind of bactericidal composition containing isopropyl metsulfovax and fludioxonil | |
| CN107787990A (en) | A kind of bactericidal composition containing fluorine ether bacterium acid amides and flumorph | |
| CN104757005A (en) | Fungicide composition containing metalaxyl and thifluzamide | |
| CN105394048A (en) | Bactericidal composition containing prothioconazole and efficient metalaxyl-M | |
| CN107361074A (en) | A kind of bactericidal composition containing pyraclostrobin Yu the gloomy copper of thiophene | |
| CN107660539A (en) | A kind of bactericidal composition containing fluopyram and copper 8-hydroxyquinolinate | |
| CN108605942A (en) | A kind of bactericidal composition containing amisulbrom and fluazinam | |
| CN103947651A (en) | Fungicidal composition containing (2,4-dinitro-6-(1-methylheptyl)phenylcrotonate,2,4-DNOPC) and difenoconazole | |
| CN104068026A (en) | Sterilization composition containing meptyldinocap and triadimenol | |
| CN104054705A (en) | Bactericidal composition containing meptyldinocap and kresoxim-methyl |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20180515 |