CN108029637B - A method of maintaining Layer Production Performance under the conditions of cold stress - Google Patents
A method of maintaining Layer Production Performance under the conditions of cold stress Download PDFInfo
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- CN108029637B CN108029637B CN201810098706.4A CN201810098706A CN108029637B CN 108029637 B CN108029637 B CN 108029637B CN 201810098706 A CN201810098706 A CN 201810098706A CN 108029637 B CN108029637 B CN 108029637B
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- 230000008645 cold stress Effects 0.000 title claims abstract description 23
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 15
- 238000000034 method Methods 0.000 title claims abstract description 15
- 239000000654 additive Substances 0.000 claims description 7
- 230000000996 additive effect Effects 0.000 claims description 7
- 241000287828 Gallus gallus Species 0.000 claims description 4
- 239000000243 solution Substances 0.000 claims description 4
- 238000001816 cooling Methods 0.000 claims description 3
- 239000004459 forage Substances 0.000 claims description 2
- 239000011521 glass Substances 0.000 claims description 2
- 239000002504 physiological saline solution Substances 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 claims description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
- 229960000935 dehydrated alcohol Drugs 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 abstract description 6
- 239000003814 drug Substances 0.000 abstract description 6
- 206010059866 Drug resistance Diseases 0.000 abstract description 4
- 239000003242 anti bacterial agent Substances 0.000 abstract description 3
- 229940088710 antibiotic agent Drugs 0.000 abstract description 3
- 238000009360 aquaculture Methods 0.000 abstract description 3
- 244000144974 aquaculture Species 0.000 abstract description 3
- 238000012423 maintenance Methods 0.000 abstract description 3
- 230000036750 egg laying performance Effects 0.000 abstract description 2
- 230000007613 environmental effect Effects 0.000 abstract description 2
- 231100000252 nontoxic Toxicity 0.000 abstract description 2
- 230000003000 nontoxic effect Effects 0.000 abstract description 2
- 235000013601 eggs Nutrition 0.000 description 21
- 238000002474 experimental method Methods 0.000 description 8
- 241001465754 Metazoa Species 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 241000271566 Aves Species 0.000 description 2
- 238000009395 breeding Methods 0.000 description 2
- 230000001488 breeding effect Effects 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 230000002708 enhancing effect Effects 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 241000272525 Anas platyrhynchos Species 0.000 description 1
- 241000282693 Cercopithecidae Species 0.000 description 1
- 229940123457 Free radical scavenger Drugs 0.000 description 1
- 231100000111 LD50 Toxicity 0.000 description 1
- YJPIGAIKUZMOQA-UHFFFAOYSA-N Melatonin Natural products COC1=CC=C2N(C(C)=O)C=C(CCN)C2=C1 YJPIGAIKUZMOQA-UHFFFAOYSA-N 0.000 description 1
- 201000010927 Mucositis Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 235000019730 animal feed additive Nutrition 0.000 description 1
- 239000003674 animal food additive Substances 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 210000000748 cardiovascular system Anatomy 0.000 description 1
- 210000004534 cecum Anatomy 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000027288 circadian rhythm Effects 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001647 drug administration Methods 0.000 description 1
- 239000003640 drug residue Substances 0.000 description 1
- 230000010224 hepatic metabolism Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 210000004347 intestinal mucosa Anatomy 0.000 description 1
- 231100000636 lethal dose Toxicity 0.000 description 1
- DRLFMBDRBRZALE-UHFFFAOYSA-N melatonin Chemical compound COC1=CC=C2NC=C(CCNC(C)=O)C2=C1 DRLFMBDRBRZALE-UHFFFAOYSA-N 0.000 description 1
- 229960003987 melatonin Drugs 0.000 description 1
- 230000037353 metabolic pathway Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 210000004560 pineal gland Anatomy 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 239000002516 radical scavenger Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 230000001932 seasonal effect Effects 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/02—Breeding vertebrates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/184—Hormones
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
- A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Birds (AREA)
- Environmental Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Biodiversity & Conservation Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Feed For Specific Animals (AREA)
- Fodder In General (AREA)
Abstract
The present invention discloses a kind of method that Layer Production Performance is maintained under the conditions of cold stress, by starting within first 1 week the feed of continuous feeding epiphysin containing given dose there's a sudden fall in temperature, reduce Layer Production Performance is influenced by low ambient temperature, is realized under the conditions of cold stress to the maintenance of Layer Production Performance.Feed addictive provided by the invention has safe and nontoxic, harmless, noresidue characteristic, cost performance is high, both it had solved by such environmental effects, especially the egg laying performance problem of laying hen the most apparent is influenced with temperature, the problem of abuse of antibiotics in aquaculture can be effectively relieved again, avoids the abuse of birds antibiotic from drug resistance and the big serious problems of medicament residue two occur.
Description
Technical field
The invention belongs to layer breeding fields, are related to a kind of method that Layer Production Performance is maintained under the conditions of cold stress.
Background technique
Performance in layers is influenced obviously by the external world, and wherein temperature is a great influence element.The suitable ring of laying hen life
Border temperature is 18-23 DEG C, but there are the influences of unfavourable weather factor in actual production process.Studies have reported that 6.8 DEG C of low temperature
Environment can significantly reduce laying hen egg production, Egg Quality and feed conversion rate (Akbari and Torki, Int J
Biometeorol.2016,60:867-71).In China, the winter, spring temperature change usually more suddenly and cooling extent
Greatly, huge adverse effect is caused to laying hen industry.According to Li Chaoguo (2008), Hubei in two weeks after snow disaster occurred in 2008
The laying rate decline 20% of laying hen, laying duck is saved, birds, beasts and eggs yield declines more than 6000 tons, more than 4,000 ten thousand yuan of economic loss.The whole nation is taken a broad view,
Winter, spring seasonal climate factor economic loss caused by laying hen industry will be huger.To find out its cause, cold stress can induce broiler chicken
Small intestinal mucosa inflammation can destroy chicken cecum microorganisms fauna and mucosa-immune barrier, therefore, in breeding layer chicken, cultivate people
Member usually copes with the decline of laying rate caused by cold stress using antibiotic, and can generate the effect got instant result.And antibiosis
The abuse of element is then necessarily accompanied with drug resistance and the big serious problems of medicament residue two.Therefore, research and development there is enhancing laying hen to resist cold
The feed addictive of stress ability is imperative.
Epiphysin (Melatonin) is mainly secreted by the pineal body of animal, is a kind of highly lipophilic amine bormones, is participated in
Adjust the circadian rhythm of animal.In addition, epiphysin is a kind of powerful endogenous free radical scavenger, function is immunized in animal body
Energy enhancing, sleep improvement, cardiovascular system adjust, inhibit cancer cell multiplication etc. with effect more outstanding.Epiphysin
Toxicity it is minimum, oral median lethal dose (LD50) > 10g/kg of rat and mouse.Epiphysin category endogenous material, in animal
Have the metabolic pathway of its own in vivo: the epiphysin in blood has 70%~75% in liver metabolism, and metabolite is through urinating
(80%) it is excreted with excrement (20%).The half-life period of epiphysin in animal body is very short, there is that researches show that epiphysins in monkey
Intracorporal half-life period is about 40 minutes, is about 20 minutes in rat and dog intracorporal half-life period.Therefore, using epiphysin as feed
Additive has many advantages, such as safety and drug residue free.In China, epiphysin category non-prescribed medicine can voluntarily be bought in pharmacy.Beauty
State's federal food drug and cosmetic act and Drug Administration (FDA) think that epiphysin is natural food, have no toxic side effect.Therefore, epiphysin can be made
For a kind of safe animal feed additive.
Summary of the invention
The purpose of the present invention is overcoming the shortcomings of the prior art, one kind is provided and maintains laying hen to produce under the conditions of cold stress
The method of egg performance is by adding 0.625mg-2.5mg epiphysin in every kilogram of conventional egg feedstuff, before there's a sudden fall in temperature
Start within 1 week continuous feeding 1 week, realizes under the conditions of cold stress to the maintenance of Layer Production Performance.
Specific step is as follows for the method for the present invention:
(1) preparation of feed addictive:
100 μ l dehydrated alcohols of 7.5-30mg epiphysin are dissolved, 50ml physiological saline is added later, is stirred with glass bar
Even, the epiphysin concentration for obtaining solution is 0.15mg/ml-0.6mg/ml；
(2) mixing of additive and feed:
(a) prepare 12Kg routine egg feedstuff；
(b) take out the above-mentioned egg feedstuff of 1Kg be sufficiently stirred with step (1) acquired solution, later again by this 1Kg feed with newly
1Kg feed mix, and so on, until 12Kg feed is mixed well；
(4) feeding method:
It can be according to Local Weather Report, 1 before there's a sudden fall in temperature (5 DEG C of cooling extent or more or daily minimal tcmperature be lower than 8 DEG C)
Start continuous feeding week.The forage volume of feeding is consistent with conventional feed amount, and difference is only to be added in every kilogram of feed
0.625mg-2.5mg epiphysin, continuous feeding can play protective effect after 1 week, during there's a sudden fall in temperature, with feeding conventional feed
Laying hen compare, mix and feed the laying rate of laying hen of this additive and can be improved 15-20%, total egg size improves 10-13%.
Feed after step (2) mixes is 1 day edible for 100 laying hens.
Feed preservation condition after step (2) mixing: epiphysin is relatively stable, can disposably prepare the feed in a week
Amount is deposited in closed, dry room temperature environment.
Existing reply laying hen cold stress method is mostly to add antibiotic using drinking-water, and the abuse of antibiotic will necessarily go out
Existing drug resistance and the big serious problems of medicament residue two.The method of the present invention is subtracted by the epiphysin of the addition suitable dose in feed
Few Layer Production Performance is influenced by low ambient temperature, is realized under the conditions of cold stress to the maintenance of Layer Production Performance.The present invention mentions
The feed addictive of confession has safe and nontoxic, harmless, noresidue characteristic, and abuse of antibiotics in aquaculture can be effectively relieved
Problem.The present invention had both been solved by such environmental effects, influenced the egg laying performance problem of laying hen the most apparent with temperature especially, again
The problem of abuse of antibiotics in aquaculture can be effectively relieved, avoids the abuse of birds antibiotic from drug resistance and medicament residue two occur
Big serious problems.
Detailed description of the invention
Fig. 1 is influence of the additive of the present invention to laying hen day laying rate under the conditions of cold stress.
Fig. 2 is influence of the additive of the present invention to average single piece of egg size under the conditions of cold stress.
Fig. 3 is influence of the additive of the present invention to egg size total during test under the conditions of cold stress.
Fig. 4 is influence of the additive of the present invention to egg hangh unit under the conditions of cold stress.
Specific embodiment
The present invention is further described in conjunction with the accompanying drawings and embodiments.
Embodiment 1
The blue brown laying hen in the sea at 200 10 monthly ages, day laying rate about 95%, be randomly divided into control group (feeding conventional feed) with
Epiphysin addition group (divides 3 groups, respectively every kilogram of feed addition 0.625mg epiphysin, 1.25mg epiphysin and 2.5mg take off black
Element), every group 50.During test, hen house temperature is dropped to from 24 DEG C rapidly to 8 DEG C and for 2 weeks by ventilating system, is made
At the cold stress of laying hen.Daily 14:00 collects the egg of each experimental group and counts and weigh.
The 14th day of feeding experiment, 0.625mg epiphysin/Kg feed, 1.25mg epiphysin/Kg feed and 2.5mg take off black
Element/Kg feeding experiment group laying hen day laying rate is higher by 30%, 25% and 28% than control group (feeding conventional feed) respectively (to be schemed
1)。
Embodiment 2
The blue brown laying hen in the sea at 200 10 monthly ages, day laying rate about 95%, be randomly divided into control group (feeding conventional feed) with
Epiphysin addition group (divides 3 groups, respectively every kilogram of feed addition 0.625mg epiphysin, 1.25mg epiphysin and 2.5mg take off black
Element), every group 50.During test, hen house temperature is dropped to from 24 DEG C rapidly to 8 DEG C and for 2 weeks by ventilating system, is made
At the cold stress of laying hen.Daily 14:00 collects the egg of each experimental group and counts and weigh.
The 14th day of feeding experiment, 0.625mg epiphysin/Kg feed, 1.25mg epiphysin/Kg feed and 2.5mg take off black
The average single piece of egg size of element/Kg feeding experiment group respectively than control group (feeding conventional feed) increase 2.40g (increasing by 4.08%),
2.47 (increasing by 4.20%) and 3.08g (increasing by 5.24%) (Fig. 2).
Embodiment 3
The blue brown laying hen in the sea at 200 10 monthly ages, day laying rate about 95%, be randomly divided into control group (feeding conventional feed) with
Epiphysin addition group (divides 3 groups, respectively every kilogram of feed addition 0.625mg epiphysin, 1.25mg epiphysin and 2.5mg take off black
Element), every group 50.During test, hen house temperature is dropped to from 24 DEG C rapidly to 8 DEG C and for 2 weeks by ventilating system, is made
At the cold stress of laying hen.Daily 14:00 collects the egg of each experimental group and counts and weigh.
During feeding experiment, to the statistical result showed of 50 laying hen total yield egg size amounts, 0.625mg epiphysin/Kg feed,
Than control group, (feeding is conventional to be raised respectively for 1.25mg epiphysin/Kg feed and the total egg size of 2.5mg epiphysin/Kg feeding experiment group
Material) increase 3706.95g (increasing by 11.11%), 3477.76 (increasing by 10.42%) and 4545.22g (increasing by 13.62%) (figure
3)。
Embodiment 4
The blue brown laying hen in the sea at 200 10 monthly ages, day laying rate about 95%, be randomly divided into control group (feeding conventional feed) with
Epiphysin addition group (divides 3 groups, respectively every kilogram of feed addition 0.625mg epiphysin, 1.25mg epiphysin and 2.5mg take off black
Element), every group 50.During test, hen house temperature is dropped to from 24 DEG C rapidly to 8 DEG C and for 2 weeks by ventilating system, is made
At the cold stress of laying hen.Daily 14:00 collects the egg of each experimental group and counts and weigh.
Hangh unit is the key index for reflecting egg freshness and albumen quality.The 14th day of feeding experiment, to egg
The statistical result showed of hangh unit, 0.625mg epiphysin/Kg feed, 1.25mg epiphysin/Kg feed and 2.5mg epiphysin/
The egg hangh unit of Kg feeding experiment group is higher by 1.35 than control group (feeding conventional feed) respectively (high 1.59%), 1.41 (high
And 1.50 (high 1.77%) (Fig. 4) 1.66%).
Claims (4)
1. a kind of method for maintaining Layer Production Performance under the conditions of cold stress, which is characterized in that by every kilogram of conventional egg
0.625 mg-2.5 mg epiphysin is added in chicken feed, beginning in first 1 week is continuously fed there's a sudden fall in temperature, especially by following step
It is rapid to realize:
(1) preparation of feed addictive:
Epiphysin is dissolved with dehydrated alcohol, physiological saline is added later, is stirred evenly with glass bar, obtaining epiphysin concentration is 0.15
The solution of mg/ml-0.6 mg/ml；
(2) mixing of additive and feed:
(a) prepare 12 Kg routine egg feedstuffs；
(b) the above-mentioned conventional egg feedstuff of 1 Kg is taken out to be sufficiently stirred with step (1) acquired solution, later again by this 1 Kg feed and
1 new Kg routine egg feedstuff mixes, and so on, until 12 Kg routine egg feedstuffs are mixed well；
(3) feeding method:
According to Local Weather Report, there's a sudden fall in temperature, beginning in first 1 week is continuously fed 1 week, the forage volume and conventional feed amount of feeding
Unanimously.
2. a kind of method for maintaining Layer Production Performance under the conditions of cold stress according to claim 1, which is characterized in that
Described there's a sudden fall in temperature, refers to 5 DEG C of cooling extent or more or daily minimal tcmperature lower than 8 DEG C.
3. a kind of method for maintaining Layer Production Performance under the conditions of cold stress according to claim 1, which is characterized in that
Feed after step (2) mixes is 1 day edible for 100 laying hens.
4. a kind of method for maintaining Layer Production Performance under the conditions of cold stress according to claim 1, which is characterized in that
Feed after step (2) mixing, which is deposited in closed, dry room temperature environment, to be saved.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810098706.4A CN108029637B (en) | 2018-01-31 | 2018-01-31 | A method of maintaining Layer Production Performance under the conditions of cold stress |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810098706.4A CN108029637B (en) | 2018-01-31 | 2018-01-31 | A method of maintaining Layer Production Performance under the conditions of cold stress |
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| Publication Number | Publication Date |
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| CN108029637A CN108029637A (en) | 2018-05-15 |
| CN108029637B true CN108029637B (en) | 2019-11-15 |
Family
ID=62097054
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| CN201810098706.4A Active CN108029637B (en) | 2018-01-31 | 2018-01-31 | A method of maintaining Layer Production Performance under the conditions of cold stress |
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Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114052143A (en) * | 2021-12-02 | 2022-02-18 | 河南牧业经济学院 | Compound preparation for maintaining egg laying peak of laying hens in final egg laying period and application method |
| CN114847227A (en) * | 2022-05-27 | 2022-08-05 | 中国科学院西北生态环境资源研究院 | Construction method and application of sheep chronic cold stress model |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104705253A (en) * | 2015-02-16 | 2015-06-17 | 中国农业大学 | Method for improving egg laying rate of egg layers |
| CN105596328A (en) * | 2016-02-02 | 2016-05-25 | 中国农业大学 | Method for delaying reproduction function decline of female animals |
| CN106689049A (en) * | 2016-12-05 | 2017-05-24 | 全椒县城西畜牧养殖专业合作社 | Quick raising method of imitated wild free-range chickens |
-
2018
- 2018-01-31 CN CN201810098706.4A patent/CN108029637B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104705253A (en) * | 2015-02-16 | 2015-06-17 | 中国农业大学 | Method for improving egg laying rate of egg layers |
| CN105596328A (en) * | 2016-02-02 | 2016-05-25 | 中国农业大学 | Method for delaying reproduction function decline of female animals |
| CN106689049A (en) * | 2016-12-05 | 2017-05-24 | 全椒县城西畜牧养殖专业合作社 | Quick raising method of imitated wild free-range chickens |
Non-Patent Citations (1)
| Title |
|---|
| 《褪黑素如何影响雌性动物的繁殖》;中国畜牧杂志;《褪黑素如何影响雌性动物的繁殖》;20170612;倒数第2段 * |
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