CN108024997A - 用加波沙朵治疗发育障碍的方法 - Google Patents

用加波沙朵治疗发育障碍的方法 Download PDF

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Publication number
CN108024997A
CN108024997A CN201680054308.1A CN201680054308A CN108024997A CN 108024997 A CN108024997 A CN 108024997A CN 201680054308 A CN201680054308 A CN 201680054308A CN 108024997 A CN108024997 A CN 108024997A
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Prior art keywords
hours
gaboxadol
pharmaceutical composition
pharmaceutically acceptable
acceptable salt
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CN201680054308.1A
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English (en)
Chinese (zh)
Inventor
马修·杜林
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Ovid Therapeutics Inc
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Ovid Therapeutics Inc
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Priority to CN202310549878.XA priority Critical patent/CN116531370A/zh
Publication of CN108024997A publication Critical patent/CN108024997A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CN201680054308.1A 2015-07-17 2016-07-14 用加波沙朵治疗发育障碍的方法 Pending CN108024997A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202310549878.XA CN116531370A (zh) 2015-07-17 2016-07-14 用加波沙朵治疗发育障碍的方法

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201562193717P 2015-07-17 2015-07-17
US62/193,717 2015-07-17
US201562207595P 2015-08-20 2015-08-20
US62/207,595 2015-08-20
US201662332567P 2016-05-06 2016-05-06
US62/332,567 2016-05-06
US201662346763P 2016-06-07 2016-06-07
US62/346,763 2016-06-07
PCT/US2016/042238 WO2017015049A1 (en) 2015-07-17 2016-07-14 Methods of treating developmental disorders with gaboxadol

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202310549878.XA Division CN116531370A (zh) 2015-07-17 2016-07-14 用加波沙朵治疗发育障碍的方法

Publications (1)

Publication Number Publication Date
CN108024997A true CN108024997A (zh) 2018-05-11

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CN202310549878.XA Pending CN116531370A (zh) 2015-07-17 2016-07-14 用加波沙朵治疗发育障碍的方法
CN201680054308.1A Pending CN108024997A (zh) 2015-07-17 2016-07-14 用加波沙朵治疗发育障碍的方法

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Country Status (17)

Country Link
US (8) US20170014393A1 (https=)
EP (2) EP4541420A3 (https=)
JP (3) JP2018520189A (https=)
KR (2) KR20180031721A (https=)
CN (2) CN116531370A (https=)
AU (2) AU2016295138B2 (https=)
BR (1) BR112018000933A2 (https=)
CA (1) CA2992734A1 (https=)
CL (1) CL2018000142A1 (https=)
CO (1) CO2018000375A2 (https=)
ES (1) ES3021189T3 (https=)
HK (1) HK1250951A1 (https=)
IL (2) IL256912B2 (https=)
MX (2) MX391708B (https=)
PE (2) PE20230735A1 (https=)
TW (2) TW202325293A (https=)
WO (1) WO2017015049A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112739353A (zh) * 2018-06-14 2021-04-30 奥维德医疗公司 Mir-92a或mir-145在治疗安格曼综合征中的用途
CN112930182A (zh) * 2018-09-20 2021-06-08 奥维德医疗公司 加波沙朵用于治疗图雷特综合征、抽搐和口吃的用途

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RS62007B1 (sr) 2014-06-06 2021-07-30 Ovid Therapeutics Inc Postupci pojačavanja tonične inhibicije i lečenja angelmanovog sindroma
EP4541420A3 (en) 2015-07-17 2025-06-25 Ovid Therapeutics Inc. Methods of treating developmental disorders with gaboxadol
EP3481387A4 (en) 2016-08-11 2020-04-08 Ovid Therapeutics Inc METHOD AND COMPOSITIONS FOR TREATING EPILEPTIC DISEASES
CN110225754A (zh) * 2016-11-22 2019-09-10 奥维德医疗公司 用氟吡汀治疗发育障碍和/或癫痫发作紊乱的方法
US10071083B2 (en) * 2017-02-03 2018-09-11 Ovid Therapeutics Inc Use of gaboxadol in the treatment of tinnitus
US20180338959A1 (en) * 2017-05-24 2018-11-29 Ovid Therapeutics Inc. Treatment of depressive disorders
JP2020529440A (ja) 2017-08-04 2020-10-08 オービッド・セラピューティクス・インコーポレイテッドＯｖｉｄ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． 糖尿病および関連する状態の処置におけるガボキサドールの使用
EP3711761A4 (en) * 2017-11-14 2021-11-24 SK Biopharmaceuticals Co., Ltd. USE OF A CARBAMATE COMPOUND TO REDUCE OR TREAT DEVELOPMENTAL DISORDERS, INCLUDING FRAGILE X SYNDROME, ANGELMAN'S SYNDROME, OR RETT'S SYNDROME
CN112888437A (zh) * 2018-08-22 2021-06-01 奥维德医疗公司 加波沙朵在治疗胃肠道紊乱和哮喘中的用途
MX2021005994A (es) * 2018-11-21 2021-09-14 Certego Therapeutics Inc Combinacion de gaboxadol y litio para el tratamiento de trastornos psiquiatricos.
JP2022514194A (ja) 2018-11-21 2022-02-10 セルテゴ セラピューティクス インコーポレイテッド 自殺のリスクを低減し、うつ病を迅速に軽減するためのガボキサドール
WO2020131856A1 (en) 2018-12-17 2020-06-25 Ovid Therapeutics Inc. Use of gaboxadol for the treatment of non-24 hour sleep-wake disorder
JP7749169B2 (ja) * 2019-06-07 2025-10-06 クヴァトリス セラピューティクス， インコーポレイテッド 中枢神経系障害を処置するための組成物および方法
AU2020313930A1 (en) * 2019-07-15 2022-02-03 Ovid Therapeutics Inc. Pharmaceutical formulations containing gaboxadol for therapeutic treatment
US11364228B2 (en) 2019-12-18 2022-06-21 Ovid Therapeutics Inc. Gaboxadol for therapeutic treatment of 1p36 deletion syndrome
MX2022014599A (es) 2020-05-20 2022-12-16 Certego Therapeutics Inc Gaboxadol deuterado en anillo y su uso para el tratamiento de trastornos psiquiatricos.

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112739353A (zh) * 2018-06-14 2021-04-30 奥维德医疗公司 Mir-92a或mir-145在治疗安格曼综合征中的用途
CN112930182A (zh) * 2018-09-20 2021-06-08 奥维德医疗公司 加波沙朵用于治疗图雷特综合征、抽搐和口吃的用途

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TW201707700A (zh) 2017-03-01
EP3324961B1 (en) 2025-03-19
IL305342A (en) 2023-10-01
CN116531370A (zh) 2023-08-04
MX2018000745A (es) 2018-08-15
MX391708B (es) 2025-03-21
BR112018000933A2 (en) 2018-09-04
EP3324961C0 (en) 2025-03-19
CA2992734A1 (en) 2017-01-26
EP3324961A4 (en) 2019-03-13
JP2021130687A (ja) 2021-09-09
PE20230735A1 (es) 2023-05-03
JP2018520189A (ja) 2018-07-26
US20190321342A1 (en) 2019-10-24
HK1250951A1 (zh) 2019-01-18
TWI819995B (zh) 2023-11-01
TW202325293A (zh) 2023-07-01
KR20180031721A (ko) 2018-03-28
US20230071127A1 (en) 2023-03-09
AU2021250862A1 (en) 2021-11-04
MX2022004734A (es) 2022-05-13
ES3021189T3 (en) 2025-05-26
EP3324961A1 (en) 2018-05-30
AU2016295138A1 (en) 2018-02-08
IL305342B1 (en) 2026-02-01
AU2016295138B2 (en) 2021-11-04
US20190255027A1 (en) 2019-08-22
IL256912A (en) 2018-03-29
US20180338960A1 (en) 2018-11-29
US20170014393A1 (en) 2017-01-19
IL256912B2 (en) 2024-01-01
US20190117632A1 (en) 2019-04-25
IL256912B1 (en) 2023-09-01
CL2018000142A1 (es) 2018-07-13
US20180098974A1 (en) 2018-04-12
EP4541420A2 (en) 2025-04-23
US11096929B2 (en) 2021-08-24
AU2021250862B2 (en) 2023-11-09
JP2023103375A (ja) 2023-07-26
CO2018000375A2 (es) 2018-04-19
WO2017015049A1 (en) 2017-01-26
PE20190338A1 (es) 2019-03-07
EP4541420A3 (en) 2025-06-25
KR20240160666A (ko) 2024-11-11
US12465597B2 (en) 2025-11-11
US20210030727A1 (en) 2021-02-04

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