CN108014363A - Dressing, dressing film layer and preparation method thereof - Google Patents

Dressing, dressing film layer and preparation method thereof Download PDF

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Publication number
CN108014363A
CN108014363A CN201711285934.4A CN201711285934A CN108014363A CN 108014363 A CN108014363 A CN 108014363A CN 201711285934 A CN201711285934 A CN 201711285934A CN 108014363 A CN108014363 A CN 108014363A
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mass parts
film layer
dressing
organic solvent
preparation
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CN108014363B (en
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崔华帅
史贤宁
吴鹏飞
黄庆
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China Textile Academy
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China Textile Academy
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/225—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties

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  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The present invention is on a kind of dressing, dressing film layer and preparation method thereof, is related to dressing technical field, mainly solving the technical problems that fibre strength prepared by class method of electrostatic spinning is not high, dressing production efficiency prepared by the technique of braiding is low.The technical solution mainly used for：The preparation method of dressing film layer, including：Choose the sodium carboxymethyl cellulose fibre of preset range length l；The bonding of the sodium carboxymethyl cellulose fibre of first mass parts m1, the second mass parts m2 is mixed to form slurry with the organic solvent of macromolecule resin, the 3rd mass parts m3, wherein, the bonding dissolves in the organic solvent with macromolecule resin and forms adhesive；The slurry is formed on gauze, prepares and is molded the dressing film layer.Relative to the prior art, the intensity of dressing film layer is higher, and manufacture craft is simple, and thickness is easy to adjust, without operation stitching, using simple, while adds the security used, can mitigate the pain and sense of discomfort of patient.

Description

Dressing, dressing film layer and preparation method thereof
Technical field
The present invention relates to dressing technical field, more particularly to a kind of dressing, dressing film layer and preparation method thereof.
Background technology
Dressing is a kind of important auxiliary material of modern medicine, is mainly used in wound healing and skin lesion healing.By dressing Wound is fitted in, mechanical factor (such as foul, collision, inflammation) can be resisted, resist pollution and chemical stimulation, prevent two degree of senses Dye, prevents dry and body fluid from losing (electrolyte loss), prevents heat from losing, in addition to carrying out protection comprehensively to wound, moreover it is possible to Wound healing process is actively influenced by debridement, creates the microenvironment for promoting wound healing.
For example, sodium carboxymethylcellulose (Carboxymethylcellulose sodium, also known as：Sodium carboxymethylcellulose Salt, carboxymethyl cellulose, abbreviation CMC) moist dressing is exactly a kind of common new pattern compress, and it, which has, can absorb big quantity of fluid Ability, can form after sepage one layer of stable network gel in wound surface, the ring of a moistening is maintained in wound Border, is conducive to wound healing and skin regeneration.
At present, the preparation method of sodium carboxymethylcellulose moist dressing mainly has following several, and one kind is first with polycyclic oxygen The mixed solution of ethane and CMC carry out electrostatic spinning for spinning solution, and fiber cortina then is immersed in certain density nitric acid In silver-colored solution, take out and dry be placed in the air of moist room temperature is reduced in the dark, finally obtained CMC nanofibers It is loaded with the nano fibrous membrane of silver nano-grain.One kind is to use method of electrostatic spinning, and chitosan solution is projected from spinning head, is projected Chitosan solution thread be ejected into bacteria cellulose compound nonwoven cloth or woven cloths membrane material containing absolute ethyl alcohol and/or water On, it is post-treated to obtain the moist antiseptic dressing of bacteria cellulose recombination chitosan.Fiber prepared by above-mentioned class method of electrostatic spinning Intensity is not high, and pliability is bad.Another kind is used by colloidal sol fiber, is woven in by way of braiding fine by non-colloidal sol Tie up on the bottom formed and formed, the process of braiding is relatively complicated, and overall production efficiency is low.
The content of the invention
In view of this, the present invention provides a kind of dressing, dressing film layer and preparation method thereof, mainly solving the technical problems that Fibre strength prepared by class method of electrostatic spinning is not high, and dressing production efficiency prepared by the technique of braiding is low.
To reach above-mentioned purpose, present invention generally provides following technical solution：
On the one hand, the embodiment of the present invention provides a kind of preparation method of dressing film layer, including：
Choose the sodium carboxymethyl cellulose fibre of preset range length l；
By the sodium carboxymethyl cellulose fibre of the first mass parts m1, the bonding macromolecule resin of the second mass parts m2, The organic solvent of three mass parts m3 is mixed to form slurry, wherein, the bonding dissolves in the organic solvent with macromolecule resin Form adhesive；
The slurry is formed on gauze, prepares and is molded the dressing film layer.
The object of the invention to solve the technical problems can be also applied to the following technical measures to achieve further.
Optionally, foregoing preparation method, wherein the size of the preset range length l is less than or equal to more than or equal to 1mm 15mm。
Optionally, foregoing preparation method, wherein described by the sodium carboxymethyl cellulose fibre of the first mass parts m1, second The bonding of mass parts m2 is mixed to form slurry with the organic solvent of macromolecule resin, the 3rd mass parts m3, specifically includes：
The organic solvent of the sodium carboxymethyl cellulose fibre of first mass parts m1, the 4th mass parts m4 is stirred to be formed Slurries；
The bonding of second mass parts m2 is stirred with the organic solvent of macromolecule resin, the 5th mass parts m5 to be formed it is viscous Mixture；
The organic solvent of the slurries, described adhesive, the 6th mass parts m6 are stirred to form slurry.
Optionally, foregoing preparation method, wherein m1：The value range of m4 is 1：20-1：500.
Optionally, foregoing preparation method, wherein m2：The value range of m1 is 1：50-1：600.
Optionally, foregoing preparation method, wherein m1：(m4+m5+m6) value range is 1：1000-1： 5000.
Optionally, foregoing preparation method, wherein the sodium carboxymethyl cellulose fibre of the first mass parts m1, the 4th mass parts The time of the organic solvent stirring of m4 is 5-15min.
Optionally, foregoing preparation method, wherein the sodium carboxymethyl cellulose fibre of the first mass parts m1, the 4th mass parts The speed of the organic solvent stirring of m4 is 20000-30000r/min.
Optionally, foregoing preparation method, wherein the slurries, described adhesive, the organic solvent of the 6th mass parts m6 The speed of stirring is 10000-20000r/min.
Optionally, foregoing preparation method, wherein described be formed in the slurry on gauze, prepare and is molded the dressing Film layer, specifically includes：
Net is carried out to the slurry to copy, prepare and be molded the dressing film layer using gauze.
Optionally, foregoing preparation method, wherein the organic solvent includes ethanol, ether, isopropanol, acetone, diformazan One kind in yl acetamide, tetrahydrofuran, ethyl acetate, dichloromethane.
Optionally, foregoing preparation method, wherein the bonding includes poly epsilon caprolactone lactone, polylactic acid-glycolic with macromolecule resin At least one of acetic acid copolymer, polylactic acid, 1,3- propane diols.
Optionally, foregoing preparation method, wherein the mesh number of the gauze is in 50-100 mesh.
Optionally, foregoing preparation method, wherein the dimensioned area of the gauze is in 1cm2-1m2。
Optionally, foregoing preparation method, wherein the shape of the gauze is using circular or polygon.
On the other hand, the embodiment of the present invention provides a kind of dressing film layer, and the dressing film layer is by above-mentioned dressing film layer Preparation method prepare.
Another further aspect, the embodiment of the present invention provide a kind of dressing, including：Above-mentioned dressing film layer.
By above-mentioned technical proposal, dressing that technical solution of the present invention provides, dressing film layer and preparation method thereof at least have There are following advantages：
In technical solution provided by the invention, by sodium carboxymethyl cellulose fibre, bonding macromolecule resin, organic solvent Be mixed to form slurry, slurry be formed on gauze, prepare shaping dressing membrane layer, relative to the prior art, dressing film layer it is strong Degree is higher, and manufacture craft is simple, and thickness is easy to adjust, without operation stitching, using simple, while adds the safety used Property, can mitigate the pain and sense of discomfort of patient.
Described above is only the general introduction of technical solution of the present invention, in order to better understand the technological means of the present invention, And can be practiced according to the content of specification, below with presently preferred embodiments of the present invention and coordinate detailed description as after.
Embodiment
Further to illustrate the present invention to reach the technological means and effect that predetermined goal of the invention is taken, below in conjunction with Preferred embodiment, to according to dressing proposed by the present invention, dressing film layer and preparation method thereof its embodiment, structure, spy Sign and its effect, describe in detail as after.In the following description, what different " embodiment " or " embodiment " referred to is not necessarily same One embodiment.In addition, the special characteristic, structure or feature in one or more embodiments can be combined by any suitable form.
A kind of preparation method for dressing film layer that one embodiment of the present of invention proposes, it includes：
Choose the sodium carboxymethyl cellulose fibre of preset range length l；
Wherein, the size of preset range length l can be less than or equal to 15mm, such as the carboxylic first of 3mm-10mm more than or equal to 1mm Base sodium cellulosate fiber, preferable length are 4mm-6mm.
By the sodium carboxymethyl cellulose fibre of the first mass parts m1, the bonding macromolecule resin of the second mass parts m2, The organic solvent of three mass parts m3 is mixed to form slurry, wherein, the bonding dissolves in the organic solvent with macromolecule resin Form adhesive；The organic solvent includes ethanol, ether, isopropanol, acetone, dimethylacetylamide, tetrahydrofuran, acetic acid second One kind in ester, dichloromethane.Bonding dissolves in the organic solvent, bonding macromolecule resin bag with macromolecule resin Include poly epsilon caprolactone lactone, Poly(D,L-lactide-co-glycolide (such as:PLGA370, PLGA280, PLGA190), polylactic acid, 1,3- third At least one of glycol.
Wherein, it is described by the sodium carboxymethyl cellulose fibre of the first mass parts m1, the bonding high score of the second mass parts m2 Subtree fat, the organic solvent of the 3rd mass parts m3 are mixed to form slurry, specifically include：
The organic solvent of the sodium carboxymethyl cellulose fibre of first mass parts m1, the 4th mass parts m4 is stirred to be formed Slurries；
m1：The value range of m4 is 1：20-1：500, preferably match m1：M4 is 1：35-1：200, particularly preferred proportioning m1：M4 is 1:35-1:150.The organic solvent stirring of the sodium carboxymethyl cellulose fibre, the 4th mass parts m4 of first mass parts m1 Time be 5-15min, the preferable stirring to pulp time is 8-10min, and beating time is too short cannot be by sodium carboxymethylcellulose Fiber gets tiny fine hair, and beating time is long to interrupt sodium carboxymethyl cellulose fibre, reduces intensity.First mass parts The speed that the sodium carboxymethyl cellulose fibre of m1, the organic solvent of the 4th mass parts m4 stir is 20000-30000r/min, excellent The mixing speed of choosing is 22000-28000r/min, and particularly preferred mixing speed is 25000-28000r/min.
The bonding of second mass parts m2 is stirred with the organic solvent of macromolecule resin, the 5th mass parts m5 to be formed it is viscous Mixture；
m2：The value range of m1 is 1：50-1：600, preferable m2：M1 is 1:100-1:350.
The organic solvent of the slurries, described adhesive, the 6th mass parts m6 are stirred to form slurry.
m1：(m4+m5+m6) value range is 1：1000-1：5000, preferable m1：(m4+m5+m6) value range 1: 1500-1:3500, particularly preferably 1:2000-1:3000.The slurries, described adhesive, the 6th mass parts m6 it is organic molten The speed of agent stirring is 10000-20000r/min, and preferable mixing speed is 12000-18000.
The slurry is formed on gauze, prepares and is molded the dressing film layer.
It is described that the slurry is formed on gauze, prepare and be molded the dressing film layer, specifically may include：Use gauze pair The slurry carries out net and copies, and prepares and is molded the dressing film layer.
For the mesh number of the gauze in 50-100 mesh, preferable gauze mesh number is 60-80 mesh.The dimensioned area of the gauze exists 1cm2-1m2, preferable gauze dimensioned area is 10cm2-60cm2.The shape of the gauze uses circular or polygon, for example, Triangle, square, rectangle, trapezoidal, star, diamond shape etc..
In technical solution provided by the invention, by sodium carboxymethyl cellulose fibre, bonding macromolecule resin, organic solvent Be mixed to form slurry, slurry be formed on gauze, prepare shaping dressing membrane layer, relative to the prior art, dressing film layer it is strong Degree is higher, and manufacture craft is simple, and thickness is easy to adjust, without operation stitching, using simple, while adds the safety used Property, can mitigate the pain and sense of discomfort of patient.
A kind of dressing film layer that one embodiment of the present of invention proposes, dressing film layer are prepared by the above method.Specifically , the dressing film layer grammes per square metre can be 5-50g/m2, thickness is 80-500 μm.
A kind of dressing that one embodiment of the present of invention proposes, is prepared by above-mentioned dressing film layer.
Embodiment 1
Using the sodium carboxymethyl cellulose fibre 3g that length is 6mm, it is added in ethyl acetate solvent, carboxymethyl cellulose Sodium fiber is 1 with ethyl acetate proportioning:50, it is beaten, beating rate 25000r/min, is beaten in high-speed mixing equipment Time is 10min, forms slurries.Polylactic resin is added in ethyl acetate and prepares composite adhesives, polylactic resin and carboxylic The mass ratio of sodium carboxymethylcellulose pyce fiber is 1：50.Slurries and adhesive are mixed and continue to add ethyl acetate solvent to carboxylic first The quality proportioning of base sodium cellulosate fiber and ethyl acetate solvent is 1：1500, high-speed stirred, mixing speed 15000r/ Min, finally using 10cm2Circular gauze net copy and make its film forming, thickness is 280 μm, grammes per square metre 30g/m2。
Embodiment 2
Using the sodium carboxymethyl cellulose fibre 5g that length is 6mm, it is added in ethyl acetate solvent, carboxymethyl cellulose Sodium fiber is 1 with ethyl acetate proportioning:70, it is beaten, beating rate 20000r/min, is beaten in high-speed mixing equipment Time is 12min, forms slurries.Polylactic resin is added in ethyl acetate and prepares composite adhesives, polylactic resin and carboxylic The mass ratio of sodium carboxymethylcellulose pyce fiber is 1：60.Slurries and adhesive are mixed and continue to add ethyl acetate solvent to carboxylic first The quality proportioning of base sodium cellulosate fiber and ethyl acetate solvent is 1：2000, high-speed stirred, mixing speed 13000r/ Min, finally using 10cm2Square gauze net copy and make its film forming, thickness is 500 μm, grammes per square metre 50g/cm2。
Embodiment 3
Using the sodium carboxymethyl cellulose fibre 3g that length is 5mm, it is added in dichloromethane solvent, carboxymethyl cellulose Sodium fiber is 1 with dichloromethane proportioning:70, it is beaten, beating rate 20000r/min, is beaten in high-speed mixing equipment Time is 12min, forms slurries.Polylactic resin is added in dichloromethane and prepares composite adhesives, polylactic resin and carboxylic The mass ratio of sodium carboxymethylcellulose pyce fiber is 1：60.Slurries and adhesive are mixed and continue to add dichloromethane solvent to carboxylic first The quality proportioning of base sodium cellulosate fiber and dichloromethane solvent is 1：2000, high-speed stirred, mixing speed 13000r/ Min, finally using 10cm2Square gauze net copy and make its film forming, thickness is 280 μm, grammes per square metre 30g/cm2。
Embodiment 4
Using the sodium carboxymethyl cellulose fibre 6g that length is 5mm, it is added in dichloromethane solvent, carboxymethyl cellulose Sodium fiber is 1 with dichloromethane proportioning:100, it is beaten in high-speed mixing equipment, beating rate 28000r/min, beats The slurry time is 10min, forms slurries.Poly(D,L-lactide-co-glycolide resin is added in dichloromethane and is configured to bond The mass ratio of agent, Poly(D,L-lactide-co-glycolide resin and sodium carboxymethyl cellulose fibre is 1：100.Continue to add dichloro Methane solvent to the quality proportioning of sodium carboxymethyl cellulose fibre and dichloromethane solvent is 1：3000, high-speed stirred, stirring speed Spend for 15000r/min, finally using 1cm2Diamond shape gauze net copy and make its film forming, thickness is 80 μm, grammes per square metre 6g/cm2。
Embodiment 5
Using the sodium carboxymethyl cellulose fibre staple fiber 3g that length is 4mm, it is added in anhydrous ethanol solvent, CMC is short Fiber is 1 with absolute ethyl alcohol proportioning:100, it is beaten, beating rate 28000r/min, is beaten in high-speed mixing equipment Time is 10min.Sodium carboxymethyl cellulose fibre is added in hydrous ethanol and prepares composite adhesives, CMC and CMC staple fibers Mass ratio is 1：100.It is 1 to continue to add anhydrous ethanol solvent to matching：3000, high-speed stirred, mixing speed 15000r/ Min, finally using 0.5m2Triangle diddle-net make its film forming, thickness is 80 μm, grammes per square metre 6g/m2。
Embodiment 6
Using the sodium carboxymethyl cellulose fibre 3g that length is 5mm, it is added in tetrahydrofuran solvent, carboxymethyl cellulose Sodium fiber is 1 with tetrahydrofuran proportioning:100, it is beaten in high-speed mixing equipment, beating rate 30000r/min, beats The slurry time is 15min, forms slurries.Poly epsilon caprolactone lactone resin is added in tetrahydrofuran and prepares composite adhesives, poly epsilon caprolactone lactone The mass ratio of resin and sodium carboxymethyl cellulose fibre is 1：100.Continue to add tetrahydrofuran solvent to sodium carboxymethylcellulose The quality proportioning of fiber and tetrahydrofuran solvent is 1：3000, high-speed stirred, mixing speed 15000r/min, finally uses 20cm2Star-like gauze net copy and make its film forming, thickness is 150 μm, grammes per square metre 15g/cm2。
In the above-described embodiments, the description to each embodiment all emphasizes particularly on different fields, and does not have the portion being described in detail in some embodiment Point, it may refer to the associated description of other embodiment.
It is understood that the correlated characteristic in above device can be referred to mutually.In addition, in above-described embodiment " the One ", " second " etc. is to be used to distinguish each embodiment, and does not represent the quality of each embodiment.
In the specification that this place provides, numerous specific details are set forth.It is to be appreciated, however, that the implementation of the present invention Example can be put into practice in the case of these no details.In some instances, known structure and skill is not been shown in detail Art, so as not to obscure the understanding of this description.
Similarly, it will be appreciated that in order to simplify the disclosure and help to understand one or more of each inventive aspect, Above in the description to the exemplary embodiment of the present invention, each feature of the invention is grouped together into single embodiment sometimes Or in descriptions thereof.However, the device of the disclosure should be construed to reflect following intention：I.e. claimed Invention requires features more more than the feature being expressly recited in each claim.More precisely, such as following right As claim reflects, inventive aspect is all features less than single embodiment disclosed above.Therefore, it then follows tool Thus claims of body embodiment are expressly incorporated in the embodiment, wherein the conduct of each claim in itself The separate embodiments of the present invention.
Those skilled in the art, which are appreciated that, to carry out adaptively the component in the device in embodiment Change and they are arranged in one or more devices different from the embodiment.Can be the component combination in embodiment Into a component, and multiple subassemblies can be divided into addition.Except at least some in such feature are mutual Outside repulsion, any combinations can be used to all features disclosed in this specification (including adjoint claim, summary) And all components of so disclosed any device are combined.Unless expressly stated otherwise, this specification is (including adjoint Claim, summary) disclosed in each feature can be replaced by the alternative features for providing identical, equivalent or similar purpose.
In addition, it will be appreciated by those of skill in the art that although some embodiments described herein include other embodiments In included some features rather than further feature, but the combination of the feature of different embodiments means in of the invention Within the scope of and form different embodiments.For example, in the following claims, embodiment claimed is appointed One of meaning mode can use in any combination.The present invention all parts embodiment can with hardware realization, or Realized with combinations thereof.
It should be noted that the present invention will be described rather than limits the invention for above-described embodiment, and ability Field technique personnel can design alternative embodiment without departing from the scope of the appended claims.In the claims, Any reference symbol between bracket should not be configured to limitations on claims.Word "comprising" does not exclude the presence of not Component or component listed in the claims.Word "a" or "an" before component or component does not exclude the presence of multiple Such component or component.The present invention can be realized by means of including the device of some different components.It is some listing In the claim of component, several in these components can be embodied by same component item.Word first, Second and third use do not indicate that any order.These words can be construed to title.
The above described is only a preferred embodiment of the present invention, not make limitation in any form to the present invention, according to Any simple modification, equivalent change and modification made according to the technical spirit of the present invention to above example, still falls within this hair In the range of bright technical solution.

Claims (10)

  1. A kind of 1. preparation method of dressing film layer, it is characterised in that including：
    Choose the sodium carboxymethyl cellulose fibre of preset range length l；
    By the sodium carboxymethyl cellulose fibre of the first mass parts m1, the bonding macromolecule resin of the second mass parts m2, the 3rd matter The organic solvent of amount part m3 is mixed to form slurry, wherein, the bonding dissolves in the organic solvent with macromolecule resin and is formed Adhesive；
    The slurry is formed on gauze, prepares and is molded the dressing film layer.
  2. 2. preparation method according to claim 1, it is characterised in that
    The size of the preset range length l is less than or equal to 15mm more than or equal to 1mm.
  3. 3. preparation method according to claim 1, it is characterised in that
    It is described by the sodium carboxymethyl cellulose fibre of the first mass parts m1, the bonding macromolecule resin of the second mass parts m2, The organic solvent of three mass parts m3 is mixed to form slurry, specifically includes：
    The organic solvent of the sodium carboxymethyl cellulose fibre of first mass parts m1, the 4th mass parts m4 are stirred to form slurry Liquid；
    The bonding of second mass parts m2 is stirred to form bonding with the organic solvent of macromolecule resin, the 5th mass parts m5 Agent；
    The organic solvent of the slurries, described adhesive, the 6th mass parts m6 are stirred to form slurry.
  4. 4. preparation method according to claim 3, it is characterised in that
    m1：The value range of m4 is 1：20-1：500.
  5. 5. preparation method according to claim 3, it is characterised in that
    m2：The value range of m1 is 1：50-1：600.
  6. 6. preparation method according to claim 3, it is characterised in that
    m1：(m4+m5+m6) value range is 1：1000-1：5000.
  7. 7. preparation method according to claim 3, it is characterised in that
    The time of the organic solvent stirring of the sodium carboxymethyl cellulose fibre, the 4th mass parts m4 of first mass parts m1 is 5- 15min；
    Preferably,
    The speed of the organic solvent stirring of the sodium carboxymethyl cellulose fibre, the 4th mass parts m4 of first mass parts m1 is 20000- 30000r/min；
    Preferably,
    The speed that the slurries, described adhesive, the organic solvent of the 6th mass parts m6 stir is 10000-20000r/min；
    Preferably,
    It is described that the slurry is formed on gauze, prepare and be molded the dressing film layer, specifically include：
    Net is carried out to the slurry to copy, prepare and be molded the dressing film layer using gauze；
    Preferably,
    The organic solvent includes ethanol, ether, isopropanol, acetone, dimethylacetylamide, tetrahydrofuran, ethyl acetate, dichloro One kind in methane；
    Preferably,
    The bonding includes poly epsilon caprolactone lactone, Poly(D,L-lactide-co-glycolide, polylactic acid, 1,3- propane diols with macromolecule resin At least one of；
    Preferably,
    The mesh number of the gauze is in 50-100 mesh；
    Preferably,
    The dimensioned area of the gauze is in 1cm2-1m2；
    Preferably,
    The shape of the gauze is using circular or polygon.
  8. A kind of 8. dressing film layer, it is characterised in that including：The dressing film layer is by any described in the claims 1-7 It is prepared by the preparation method of dressing film layer.
  9. 9. dressing film layer according to claim 8, it is characterised in that
    The dressing film layer grammes per square metre is 5-50g/m2, thickness is 80-500 μm.
  10. A kind of 10. dressing, it is characterised in that including：Dressing film layer described in the claims 8 or 9.
CN201711285934.4A 2017-12-07 2017-12-07 Dressing, dressing film layer and preparation method thereof Active CN108014363B (en)

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CN104323871A (en) * 2014-10-22 2015-02-04 首都医科大学附属北京妇产医院 Grid-shaped bracket composite membrane of pelvic floor repairing belt and use method thereof
WO2016209048A1 (en) * 2015-06-26 2016-12-29 한국생산기술연구원 Medical fiber structure comprising calcium carboxymethyl cellulose and chitosan compound, and method for preparing same

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Publication number Priority date Publication date Assignee Title
CN101049515A (en) * 2007-05-15 2007-10-10 浙江理工大学 Method for preparing medical use dressing of non-woven fabrics in wet-process cross blent from chitosan and silk fibrino
CN104207879A (en) * 2013-05-31 2014-12-17 天津法莫西医药科技有限公司 Medical dressing with sodium carboxymethylcellulose/polylactic acid sponge protection layer
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