CN108001744A - Dextran large biological molecule finished product collects crushing packing system and method automatically - Google Patents
Dextran large biological molecule finished product collects crushing packing system and method automatically Download PDFInfo
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- CN108001744A CN108001744A CN201711395355.5A CN201711395355A CN108001744A CN 108001744 A CN108001744 A CN 108001744A CN 201711395355 A CN201711395355 A CN 201711395355A CN 108001744 A CN108001744 A CN 108001744A
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- vacuum
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- 229920002307 Dextran Polymers 0.000 title claims abstract description 29
- 238000012856 packing Methods 0.000 title claims abstract description 29
- 238000000034 method Methods 0.000 title claims abstract description 14
- 238000004140 cleaning Methods 0.000 claims abstract description 21
- 230000001954 sterilising effect Effects 0.000 claims abstract description 20
- 238000004806 packaging method and process Methods 0.000 claims abstract description 18
- 238000001514 detection method Methods 0.000 claims abstract description 12
- 238000007689 inspection Methods 0.000 claims abstract description 10
- 230000001105 regulatory effect Effects 0.000 claims abstract description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 46
- 239000013078 crystal Substances 0.000 claims description 33
- 238000002156 mixing Methods 0.000 claims description 33
- 238000003860 storage Methods 0.000 claims description 31
- 238000007664 blowing Methods 0.000 claims description 26
- 239000007921 spray Substances 0.000 claims description 21
- 239000000463 material Substances 0.000 claims description 16
- 238000001035 drying Methods 0.000 claims description 15
- 238000004891 communication Methods 0.000 claims description 12
- 239000002184 metal Substances 0.000 claims description 10
- 239000002245 particle Substances 0.000 claims description 7
- 241000894006 Bacteria Species 0.000 claims description 5
- 244000144985 peep Species 0.000 claims description 5
- 239000004744 fabric Substances 0.000 claims description 4
- 238000009434 installation Methods 0.000 claims description 4
- 230000008878 coupling Effects 0.000 claims description 3
- 238000010168 coupling process Methods 0.000 claims description 3
- 238000005859 coupling reaction Methods 0.000 claims description 3
- 238000009413 insulation Methods 0.000 claims description 3
- 239000000843 powder Substances 0.000 claims description 2
- 239000000686 essence Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 239000000428 dust Substances 0.000 abstract description 9
- 238000004519 manufacturing process Methods 0.000 abstract description 8
- 230000000813 microbial effect Effects 0.000 abstract description 3
- 230000003749 cleanliness Effects 0.000 abstract description 2
- 239000000047 product Substances 0.000 description 21
- 238000010521 absorption reaction Methods 0.000 description 3
- 238000007599 discharging Methods 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 238000005453 pelletization Methods 0.000 description 3
- 239000008213 purified water Substances 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000025518 detection of mechanical stimulus involved in sensory perception of wind Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 230000002906 microbiologic effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000036651 mood Effects 0.000 description 1
- 238000012858 packaging process Methods 0.000 description 1
- 238000004886 process control Methods 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B37/00—Supplying or feeding fluent-solid, plastic, or liquid material, or loose masses of small articles, to be packaged
- B65B37/14—Supplying or feeding fluent-solid, plastic, or liquid material, or loose masses of small articles, to be packaged by pneumatic feeders
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C21/00—Disintegrating plant with or without drying of the material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C23/00—Auxiliary methods or auxiliary devices or accessories specially adapted for crushing or disintegrating not provided for in preceding groups or not specially adapted to apparatus covered by a single preceding group
- B02C23/08—Separating or sorting of material, associated with crushing or disintegrating
- B02C23/14—Separating or sorting of material, associated with crushing or disintegrating with more than one separator
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C23/00—Auxiliary methods or auxiliary devices or accessories specially adapted for crushing or disintegrating not provided for in preceding groups or not specially adapted to apparatus covered by a single preceding group
- B02C23/18—Adding fluid, other than for crushing or disintegrating by fluid energy
- B02C23/20—Adding fluid, other than for crushing or disintegrating by fluid energy after crushing or disintegrating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B57/00—Automatic control, checking, warning, or safety devices
Abstract
The invention belongs to dextran large biological molecule production field, and in particular to dextran large biological molecule finished product collects crushing packing system and method automatically.Automatic crushing packing system of collecting of the present invention can realize that product self-desiccation is contacted to packaging without the external world, product quality improves, cleanliness factor Testing index reaches more than 99.5%, automation mechanized operation is efficient, lower employee's amount of labour, process does not have dust generation, improve yield 0.2 0.3%, reduce occupational hazards, pass through balanced valve, regulating valve, the use of pneumatic operated valve, control system is set more to stablize, the work of employee is mainly inspection, reduce 35 people of personnel depaly, lower production cost, on-line cleaning, the use of sterilizing filter, improve service life of equipment, yield improves 0.1 0.3%；Finished product microbial limit detection 100% is qualified.
Description
Technical field
The invention belongs to large biological molecule production field, and in particular to dextran large biological molecule finished product collects powder automatically
Broken packaging system and method.
Background technology
Material is collected, is defeated, it is necessary to use the packing device that gathers materials during dextran large biological molecule is produced
Send and pack.In process of production we have found that there are problems with during dextran large biological molecule dry packing：①
General drying machine feed opening sack or truck splicing, there are dust generation, there are secondary pollution；2. the material picked out, is both needed to
The problem of being crushed after being fed intake, equally existing dust generation and labor intensity；3. large biological molecule exists viscous
Spend the material properties of big, the easy moisture absorption, material meets temperature rise or the environmental air humidity big material moisture absorption during crushing, and material holds
Easy plastic cake shape and adhesion is extremely strong, so being crushed with pulverizer, speed is slow, and yield losses are big（Normal General Loss 2-3%）, together
When the solidification of glue cake shape hold after hardness it is big, easily damage crushes machine equipment；4. former process environments clean level requires high, floor space
Greatly, package unit include drying equipment, be pulverized and mixed equipment, packaging facilities be required to build clean area can ensure product quality
（Particularly microbial limit）；5. the dust accumulation produced in packaging process, in installations and facilities, the moisture run into air is fast
The fast moisture absorption becomes plastic cake shape, and clears up difficult；6. equipment cleaning is difficult, the cleaning inside equipment, pipeline, answers product performance to clear up
It is difficult.
The content of the invention
To solve the above problems, the present invention provides a kind of dextran large biological molecule finished product to collect crushing packing automatically
System, concrete technical scheme are as follows：
Dextran large biological molecule finished product collects crushing packing system, including drying machine, the discharge port of the drying machine automatically
Connected with the feed inlet of pulverizer, the discharge port of the pulverizer is connected by the feed inlet of pipeline and feed bin, the feed bin
Discharge port is connected by the feed inlet of vacuum feeding pipe-and-filter, and the discharge port of the filter passes through pipeline and Blowing stopper
Connection, the Blowing stopper are connected with the feed inlet of crystal temporary storage tank, and the discharge port of the crystal temporary storage tank passes through pipeline and low temperature
The feed inlet connection of spiral pulverizer, the discharge port of the spiral pulverizer of low temperature pass through vacuum feeding pipeline and cyclone separator
Feed inlet connection, the discharge port of the cyclone separator is connected by pipeline with Blowing stopper, the Blowing stopper and blending tank
Feed inlet connects, and the discharge port of the blending tank is connected by pipeline with vibrating the feed inlet of screen-dividing machine, the vibration screen-dividing machine
Discharge port connected by the feed inlet of pipeline and feeding bin, the discharge port of the feeding bin passes through vacuum feeding pipeline and whirlwind
The feed inlet connection of separator, the discharge port of the cyclone separator is connected by pipeline with packing the feed inlet of feed bin, described
The discharge port of packaging feed bin is connected by pipeline with Blowing stopper, the feed inlet connection of the Blowing stopper and metal detector, described
The discharge port of metal detector is connected by pipeline with automatic packaging machine.
Preferably, the feed bin and filter are both provided with two, two feed bin the using and the reserved, the filter is
0.22 micron of sterile stud filter, the pulverizer are pendulum Roughpulverizer, and pendulum Roughpulverizer can realize two
The exchange of feed bin is fed, and fast-open type observation service hatch is provided with the pulverizer, observes operating condition at any time, if there is exception can
Handled with opening；Pneumatic butterfly valve, the discharging of the feed bin are provided with pipeline between the feed inlet of the pulverizer and feed bin
Pneumatic ball valve is provided with pipeline at mouthful, cleaning discharge is provided with the vacuum feeding pipeline between the feed bin and filter
Mouthful, it is provided with bumper jar, inspection hole lamp and fast-open type peep hole, bumper jar on the feed bin and is arranged at the 1/3 of feed bin, can prevents
Particle blocks after crushing, and inspection hole lamp and fast-open type peep hole handle easy to observation and quickly abnormal conditions, the bottom of the feed bin
The wheel of strap brake piece is provided with, when such as needing the spare feed bin of integral replacing, pulls down to push and is mounted directly spare feed bin just, will not
Influence progress.
Preferably, the vacuum port of the feed bin upper end is connected by pipeline with vacuum system, the vacuum system includes
Vacuum pump set, the vacuum pump set are connected by sterilizing filter of the pipeline respectively with two groups 0.01 micron, the aseptic filtration
Device is connected by vacuum port of the pipeline respectively with feed bin upper end, on the pipeline at the air inlet of the sterilizing filter and gas outlet
It is both provided with ball valve, pneumatic air valve is provided with the pipeline at the vacuum port of the feed bin upper end, realizes that vacuum is opened, the nothing
Vacuum detection instrument and balanced valve are provided with pipeline between bacterium filter and feed bin, vacuum detection instrument can keep vacuum to examine
Survey, balanced valve can control whole system to stablize.
Preferably, the gas port of the feed bin upper end is connected by pipeline with roots blower system, the roots blower system
System includes roots blower group, and the roots blower group is connected by sterilizing filter of the pipeline respectively with two groups 0.01 micron, institute
State sterilizing filter to be connected by gas port of the pipeline respectively with feed bin upper end, at the air inlet of the sterilizing filter and gas outlet
Pipeline on be both provided with ball valve, be provided with cloth air-valve on the pipeline at the gas port of the feed bin upper end, realize the unlatching of wind, institute
State and air quantity detector and balanced valve are provided with the pipeline between sterilizing filter and feed bin, air quantity detector keeps air quantity to stablize
Operation, balanced valve control whole system are stablized.Exchanged by the unlatching of vacuum pneumatic valve, cloth air-valve, realize that material conveys；Pass through
Vacuum, the detection of wind, Balancing relization stable operation.
Preferably, the vacuum port of the filter upper end is connected by pipeline with vacuum pump set, vacuum port and vacuum machine
Balanced valve and vacuum detection instrument are provided with pipeline between group, pneumatic operated valve is provided with the vacuum port of the filter upper end
Door, is popped one's head in by vacuum detecting, when vacuum feeding tube road pressure is more than 50,000 pa, judges that filter occurs blocking, it is necessary to carry out clearly
Reason；The air port of the filter upper end is connected by pipeline with instrument wind source of the gas distributor, sets the time in blowback control interval
100-600 seconds, blowback operation is carried out to stud filter.Diameter 4- is respectively arranged with the instrument wind source of the gas distributor
The instrument wind pipeline of 12mm, pneumatic operated valve wind pipeline, balanced valve wind pipeline, the back-blowing pipeline of diameter 20-38 are, it can be achieved that pneumatic
The unlatching of valve, balanced valve, blowing valve.
Preferably, it is both provided with inspection hole lamp, cover, agitating device and thermal insulation clamp on the crystal temporary storage tank and blending tank
Set, tank body lower section set superheated water inlet and outlet piping, and than low 5-10cm of intaking, water outlet place sets exhaust-valve, set on the cover for water outlet
It is equipped with peep hole, the discharge outlet of the crystal temporary storage tank and blending tank is both provided with electric control valve, controls discharging speed, into
Pulverizer amount controls, and electric control valve is connected with the spiral pulverizer of low temperature by being flexible coupling, existed respectively on the spiral pulverizer of low temperature
Be provided with air intake filter on pulverizer stationary knife disk, movable knife disc, in the air intake filter installation 0.45mm prefilters and
The sterile fine filters of 0.01mm.
Preferably, be connected above the cyclone separator by pipeline with air-introduced machine, the air-introduced machine by pipeline and
Water curtain dust pelletizing system is connected, and realizes vent gas treatment；Feed pipe in the feeding bin enters feed bin 3-5cm, in feeding bin
Discharge nozzle is apart from bottom 3-5cm.
Preferably, the dextran large biological molecule finished product collects crushing packing system automatically is additionally provided with cleaning system
System, cleaning system can realize on-line cleaning, and the cleaning system includes overheat water system and pure water system, the overheat water system
It is connected respectively with the water inlet on feed bin, crystal temporary storage tank, blending tank, filter by pipeline with the water outlet of pure water system,
Ball valve is both provided with the pipeline of the water outlet of the overheat water system and pure water system, the feed bin, crystal temporary storage tank, mix
Close tank, the water inlet on filter is both provided with pneumatic operated valve, the feed bin, crystal temporary storage tank, blending tank, be all provided with filter
Spray tube is equipped with, spray head is provided with spray tube, spray tube is connected with water inlet, and the nozzle in the feed bin and filter is
Fan-shaped 60 degree spray heads, the nozzle in the crystal temporary storage tank and blending tank is 360 degree of rotary spray heads, crystal temporary storage tank with
Exhaust-valve is set before electric control valve below blending tank, what the spiral pulverizer of low temperature and vibration screen-dividing machine were connected with cyclone separator
Exhaust-valve is set on pipeline.Cleaning is after being cleaned up with hot water, then is washed with purified water.
Preferably, further including control system, the control system includes controller data communication system, described pneumatic
Valve, electric control valve, balanced valve and vacuum detection instrument, air quantity detector are electrically connected with controller data communication system, control
Device data communication system includes detector transmitter and pneumatic operated valve, electric control valve, balance valve actuator, the controller data
Communication system is connected with operation microcomputer, and the control system can realize field control, can further realize that computer is online remote
Process control.
The invention also discloses a kind of dextran large biological molecule finished product to collect crushing packing method automatically, using as follows
Technical solution：
A kind of dextran large biological molecule finished product collects crushing packing method automatically, it is characterised in that：Appointed by claim 1-9
Automatic crushing packing system of collecting described in one is completed, and is comprised the following steps：
（1）1000 crystal of dextran large biological molecule into drying machine drying to viscosity be ten thousand centipoises of 5-10, into pendulum
Roughpulverizer carries out coarse crushing, and grain diameter 3-4 millimeters after coarse crushing, the particle after coarse crushing is entered by vacuum feeding pipeline
0.22 micron of sterile stud filter is filtered.The time in blowback control interval is set as 100-600 seconds, passes through instrument wind source of the gas
Distributor carries out blowback operation to 0.22 micron of sterile stud filter, and in fill process, material contact is filter
Outer layer, for a long time filter surfaces have dust attachment, feeding slows, and blowback is to ensure that material feeding is normal and protects
Demonstrate,prove the service life of filter；Material conveying, in mixed process with extraneous mere contact be air, filterings at different levels in system
The use of device, is that the air for ensureing to contact with material is germ-free condition, so as to reach raising and the stabilization of final product quality, especially
It is microbial limit.
（2）Particle enters in crystal temporary storage tank by Blowing stopper to be stirred, and is realized subsequently into the spiral pulverizer of low temperature
The fine crushing of 120-300 mesh, mixing is stirred after cyclone separator is separated into blending tank, then through vibration point
Finished product is obtained after screen(ing) machine sub-sieve；
（3）Finished product enters package storehouse after entering feeding bin after feeding tube arrival cyclone separator is separated, and is then closing
Metal detector is respectively enterd under the action of wind turbine and automatic packaging machine completes packaging.
Beneficial effects of the present invention
1st, product self-desiccation is contacted to packaging without the external world, and product quality improves, and cleanliness factor Testing index reaches more than 99.5%.
2nd, efficient, attenuating employee's amount of labour, process do not have dust generation, improve yield 0.2-0.3%, reduce occupation danger
Evil.
3rd, by balanced valve, the use of regulating valve, pneumatic operated valve, control system is made more to stablize, the work of employee is mainly
Inspection, reduces personnel depaly 3-5 people, lowers production cost.
4th, the use of on-line cleaning, sterilizing filter, improves service life of equipment, and yield improves 0.1-0.3%；Finished product is micro-
Biological limit detection 100% is qualified.
5th, the present invention only need to set up clean area in package mouth, remaining equipment be arranged on general production district can, clean area
It is greatly decreased, general production area expands, and production management and safety management rank reduce；Save fixed investment input, enterprise's pipe
Reason is more convenient.
6th, cleaning system carries out equipment, the cleaning inside pipeline with 85 degree of hot water or steam, product dissolving, cleaning effect compared with
It is good, after hot water cleans up, then washed with purified water, may further ensure that the clean level of cleaning.
Brief description of the drawings
Fig. 1 is the structure diagram of embodiment 1.
In figure：1：Drying machine；2：Pulverizer；3：Feed bin；4：Filter；5：Blowing stopper；6：Crystal temporary storage tank；7：Low temperature spiral shell
Revolve pulverizer；8：Cyclone separator；9：Blending tank；10：Vibrate screen-dividing machine；11：Feeding bin；12：Exhaust-valve；13：Package
Storehouse；14：Metal detector；15：Automatic packaging machine；16：Fast-open type observes service hatch；17：Bumper jar；18：Inspection hole lamp；19：Wheel
Son；20：Vacuum pump set；21：Sterilizing filter；22：Vacuum detection instrument；23：Balanced valve；24：Cleaning discharge port；25：Roots's wind
Unit；26：Air quantity detector；27：Spray tube；28：Spray head；29：Overheat water system；30：Pure water system；31：Instrument general mood
Source distributor；32：Air intake filter；33：Air-introduced machine；34：Water curtain dust pelletizing system.
Embodiment
With reference to specific implementation case, the invention will be further described.
Embodiment 1
Dextran large biological molecule finished product collects crushing packing system, including drying machine 1, the discharging of the drying machine 1 automatically
Mouth is connected with the feed inlet of pulverizer 2, and the discharge port of the pulverizer 2 is connected by pipeline with the feed inlet of feed bin 3, the material
The discharge port in storehouse 3 is connected by the feed inlet of vacuum feeding pipe-and-filter 4, and the discharge port of the filter 4 passes through pipeline
It is connected with Blowing stopper 5, the Blowing stopper 5 is connected with the feed inlet of crystal temporary storage tank 6, and the discharge port of the crystal temporary storage tank 6 leads to
The feed inlet of piping pulverizer 7 spiral with low temperature is connected, and the discharge port of the spiral pulverizer 7 of low temperature passes through vacuum feeding pipe
Road is connected with the feed inlet of cyclone separator 8, and the discharge port of the cyclone separator 8 is connected by pipeline with Blowing stopper, described
Blowing stopper is connected with the feed inlet of blending tank 9, and the discharge port of the blending tank 9 passes through pipeline with vibrating the feed inlet of screen-dividing machine 10
Connection, the discharge port of the vibration screen-dividing machine 10 are connected by pipeline with the feed inlet of feeding bin 11, and the feeding bin 11 goes out
Material mouth is connected by the feed inlet of vacuum feeding pipeline and cyclone separator, the discharge port of the cyclone separator by pipeline with
The feed inlet connection of feed bin 13 is packed, the discharge port of the packaging feed bin 13 is connected by pipeline with Blowing stopper, the Blowing stopper
It is connected with the feed inlet of metal detector 14, the discharge port of the metal detector 14 is connected by pipeline and automatic packaging machine 15
Connect.
Preferably, the feed bin 3 and filter 4 are both provided with two, the filter 4 is 0.22 micron of sterile stud
Filter, the pulverizer 2 are pendulum Roughpulverizer, and fast-open type observation service hatch 16 is provided with the pulverizer, described
Pneumatic butterfly valve is provided with pipeline between the feed inlet of pulverizer 2 and feed bin 3, on the pipeline of the discharge outlet of the feed bin 3
Pneumatic ball valve is provided with, cleaning discharge port 24 is provided with the vacuum feeding pipeline between the feed bin 3 and filter 4, it is described
Bumper jar 17, inspection hole lamp 18 and fast-open type observation service hatch 16 are provided with feed bin 3, the bottom of the feed bin 3 is provided with band and stops
The wheel 19 of car piece.
Preferably, the vacuum port of 3 upper end of feed bin is connected by pipeline with vacuum system, the vacuum system includes
Vacuum pump set 20, the vacuum pump set 20 are connected by sterilizing filter 21 of the pipeline respectively with two groups 0.01 micron, the nothing
Bacterium filter 21 is connected by vacuum port of the pipeline respectively with 3 upper end of feed bin, the air inlet and outlet of the sterilizing filter 21
Ball valve is both provided with pipeline at mouthful, and pneumatic air valve, the nothing are provided with the pipeline at the vacuum port of 3 upper end of feed bin
Vacuum detection instrument 22 and balanced valve 23 are provided with pipeline between bacterium filter 21 and feed bin 3.
Preferably, the gas port of 3 upper end of feed bin is connected by pipeline with roots blower system, the roots blower system
System includes roots blower group 25, and the roots blower group 25 is connected by sterilizing filter of the pipeline respectively with two groups 0.01 micron
Connect, the sterilizing filter is connected by gas port of the pipeline respectively with 3 upper end of feed bin, the air inlet of the sterilizing filter and is gone out
It is both provided with ball valve on pipeline at gas port, cloth air-valve is provided with the pipeline at the gas port of 3 upper end of feed bin, it is described sterile
Air quantity detector 26 and balanced valve are provided with pipeline between filter and feed bin 3.
Preferably, the vacuum port of 4 upper end of filter is connected by pipeline with vacuum pump set 20, vacuum port and vacuum
Balanced valve and vacuum detection instrument are provided with pipeline between unit, is provided with the vacuum port of 4 upper end of filter pneumatic
Valve；The air port of 4 upper end of filter is connected by pipeline with instrument wind source of the gas distributor 31, the instrument wind source of the gas point
With instrument wind pipeline, pneumatic operated valve wind pipeline, balanced valve wind pipeline, the diameter 20- that diameter 4-12mm is respectively arranged with device 31
38 back-blowing pipeline.
Preferably, it is both provided with inspection hole lamp, cover, agitating device and insulation on the crystal temporary storage tank 6 and blending tank 9
Chuck, is provided with peep hole on the cover, and the discharge outlet of the crystal temporary storage tank 6 and blending tank 9 is both provided with electric adjustable
Valve is saved, electric control valve is connected with the spiral pulverizer of low temperature by being flexible coupling, determines respectively in pulverizer on the spiral pulverizer of low temperature
Be provided with air intake filter 32 on cutterhead, movable knife disc, in the air intake filter installation 0.45mm prefilters and 0.01mm without
Bacterium fine filter.
Preferably, the top of cyclone separator 8 is connected by pipeline with air-introduced machine 33, the air-introduced machine 33 passes through pipe
Road is connected with water curtain dust pelletizing system 34；Feed pipe in the feeding bin 11 enters feed bin 3-5cm, the discharge nozzle in feeding bin
Apart from bottom 3-5cm.
Preferably, the dextran large biological molecule finished product collects crushing packing system automatically is additionally provided with cleaning system
System, the cleaning system include overheat water system 29 and pure water system 30, and the overheat water system 29 and pure water system 30 go out
The mouth of a river is connected with the water inlet on feed bin 3, crystal temporary storage tank 6, blending tank 9, filter 4 respectively by pipeline, the superheated water
Ball valve, the feed bin 3, crystal temporary storage tank 6, blending tank are both provided with the pipeline of the water outlet of system 29 and pure water system 30
9th, the water inlet on filter 4 is both provided with pneumatic operated valve, the feed bin 3, crystal temporary storage tank 6, blending tank 9, in filter 4
Spray tube 27 is provided with, spray head 28 is provided with spray tube 27, spray tube 27 is connected with water inlet, the feed bin 3 and filtering
Nozzle in device 4 is fan-shaped 60 degree of spray heads, and the nozzle in the crystal temporary storage tank 6 and blending tank 9 is 360 degree of rotary sprays
Head, sets exhaust-valve 12, the spiral pulverizer 7 of low temperature and vibration point before the electric control valve below crystal temporary storage tank 6 and blending tank 9
Exhaust-valve is set on the pipeline that screen(ing) machine 10 is connected with cyclone separator.
Preferably, the dextran large biological molecule finished product collects crushing packing system automatically further includes control system
System, the control system include controller data communication system, the pneumatic operated valve, electric control valve, balanced valve and vacuum detecting
Instrument, air quantity detector are electrically connected with controller data communication system, and controller data communication system includes detector transmitter
With pneumatic operated valve, electric control valve, balance valve actuator, the controller data communication system is connected with operation microcomputer, the control
System processed can realize field control, can further realize the online remote control of computer.
Embodiment 2
A kind of dextran large biological molecule finished product collects crushing packing method automatically, it is characterised in that：By any of the above-described described
Automatic crushing packing system of collecting complete, comprise the following steps：
（1）1000 crystal of dextran large biological molecule into drying machine drying to viscosity be ten thousand centipoises of 5-10, into pendulum
Roughpulverizer carries out coarse crushing, and grain diameter 3-4 millimeters after coarse crushing, the particle after coarse crushing is entered by vacuum feeding pipeline
0.22 micron of sterile stud filter is filtered, and is set the time in blowback control interval as 100-600 seconds, is passed through instrument wind source of the gas
Distributor carries out blowback operation to 0.22 micron of sterile stud filter；
（2）Particle enters in crystal temporary storage tank by Blowing stopper to be stirred, and 120- is realized subsequently into the spiral pulverizer of low temperature
The fine crushing of 300 mesh, mixing is stirred after cyclone separator is separated into blending tank, then through vibrating screen-dividing machine
Finished product is obtained after sub-sieve；
（3）Finished product enters package storehouse after entering feeding bin after feeding tube arrival cyclone separator is separated, and is then closing
Metal detector is respectively enterd under the action of wind turbine and automatic packaging machine completes packaging.
Claims (10)
1. dextran large biological molecule finished product collects crushing packing system automatically, it is characterised in that including drying machine（1）, institute
State drying machine（1）Discharge port and pulverizer（2）Feed inlet connection, the pulverizer（2）Discharge port pass through pipeline with material
Storehouse（3）Feed inlet connection, the feed bin（3）Discharge port pass through vacuum feeding pipe-and-filter（4）Feed inlet connection,
The filter（4）Discharge port pass through pipeline and Blowing stopper（5）Connection, the Blowing stopper（5）With crystal temporary storage tank（6）Into
Material mouth connects, the crystal temporary storage tank（6）Discharge port pass through pipeline and the spiral pulverizer of low temperature（7）Feed inlet connection, institute
State the spiral pulverizer of low temperature（7）Discharge port pass through vacuum feeding pipeline and cyclone separator（8）Feed inlet connection, the rotation
Wind separator（8）Discharge port be connected by pipeline with Blowing stopper, the Blowing stopper and blending tank（9）Feed inlet connection, institute
State blending tank（9）Discharge port pass through pipeline with vibration screen-dividing machine（10）Feed inlet connection, the vibration screen-dividing machine（10）'s
Discharge port passes through pipeline and feeding bin（11）Feed inlet connection, the feeding bin（11）Discharge port pass through vacuum feeding pipeline
It is connected with the feed inlet of cyclone separator, the discharge port of the cyclone separator passes through pipeline and packaging feed bin（13）Feed inlet
Connection, the packaging feed bin（13）Discharge port be connected by pipeline with Blowing stopper, the Blowing stopper and metal detector（14）
Feed inlet connection, the metal detector（14）Discharge port pass through pipeline and automatic packaging machine（15）Connection.
2. dextran large biological molecule finished product collects crushing packing system automatically according to claim 1, it is characterised in that：
The feed bin（3）And filter（4）Two are both provided with, the filter（4）It is described for 0.22 micron of sterile stud filter
Pulverizer（2）For pendulum Roughpulverizer, the pulverizer（2）On be provided with fast-open type observation service hatch（16）, the crushing
Machine（2）With feed bin（3）Feed inlet between pipeline on be provided with Pneumatic butterfly valve, the feed bin（3）Discharge outlet pipeline
On be provided with pneumatic ball valve, the feed bin（3）With filter（4）Between vacuum feeding pipeline on be provided with cleaning discharge port
（24）, the feed bin（3）On be provided with bumper jar（17）, inspection hole lamp（18）Service hatch is observed with fast-open type（16）, the feed bin
（3）Bottom be provided with the wheel of strap brake piece（19）.
3. dextran large biological molecule finished product collects crushing packing system automatically according to claim 1, it is characterised in that：
The feed bin（3）The vacuum port of upper end is connected by pipeline with vacuum system, and the vacuum system includes vacuum pump set（20）, institute
State vacuum pump set（20）Pass through the pipeline sterilizing filter with two groups 0.01 micron respectively（21）Connection, the sterilizing filter
（21）By pipeline respectively with feed bin（3）The vacuum port connection of upper end, the sterilizing filter（21）Air inlet and gas outlet
Ball valve, the feed bin are both provided with the pipeline at place（3）Pneumatic air valve, the nothing are provided with pipeline at the vacuum port of upper end
Bacterium filter（21）With feed bin（3）Between pipeline on be provided with vacuum detection instrument（22）And balanced valve（23）.
4. dextran large biological molecule finished product collects crushing packing system automatically according to claim 3, it is characterised in that：
The feed bin（3）The gas port of upper end is connected by pipeline with roots blower system, and the roots blower system includes roots blower
Group（25）, the roots blower group（25）It is connected by sterilizing filter of the pipeline respectively with two groups 0.01 micron, it is described sterile
Filter by pipeline respectively with feed bin（3）The gas port of upper end connects, at the air inlet of the sterilizing filter and gas outlet
Ball valve, the feed bin are both provided with pipeline（3）Cloth air-valve, the sterilizing filter are provided with pipeline at the gas port of upper end
With feed bin（3）Between pipeline on be provided with air quantity detector（26）And balanced valve.
5. dextran large biological molecule finished product collects crushing packing system automatically according to claim 1, it is characterised in that：
The filter（4）The vacuum port of upper end passes through pipeline and vacuum pump set（20）Connection, the pipe between vacuum port and vacuum pump set
Balanced valve and vacuum detection instrument, the filter are provided with road（4）Operated pneumatic valve is provided with the vacuum port of upper end；The mistake
Filter（4）The air port of upper end passes through pipeline and instrument wind source of the gas distributor（31）Connection, the instrument wind source of the gas distributor
（31）On be respectively arranged with the instrument wind pipeline of diameter 4-12mm, pneumatic operated valve wind pipeline, balanced valve wind pipeline, diameter 20-38
Back-blowing pipeline.
6. dextran large biological molecule finished product collects crushing packing system automatically according to claim 1, it is characterised in that：
The crystal temporary storage tank（6）And blending tank（9）On be both provided with inspection hole lamp, cover, agitating device and insulation jacket, the cover
On be provided with peep hole, the crystal temporary storage tank（6）And blending tank（9）Discharge outlet be both provided with electric control valve, it is electronic
Regulating valve is connected by being flexible coupling with the spiral pulverizer of low temperature, respectively in pulverizer stationary knife disk, moving knife on the spiral pulverizer of low temperature
Air intake filter is provided with disk（32）, the interior installation 0.45mm prefilters of the air intake filter and the sterile essences of 0.01mm filter
Device.
7. dextran large biological molecule finished product collects crushing packing system automatically according to claim 1, it is characterised in that：
The cyclone separator（8）Top passes through pipeline and air-introduced machine（33）It is connected, the air-introduced machine（33）Removed by pipeline and water curtain
Dirt system（34）It is connected；The feeding bin（11）Interior feed pipe enters feed bin 3-5cm, and the discharge nozzle in feeding bin is the bottom of apart from
Portion 3-5cm.
8. dextran large biological molecule finished product collects crushing packing system automatically according to claim 1, it is characterised in that：
Cleaning system is additionally provided with, the cleaning system includes overheat water system（29）And pure water system（30）, the superheated water
System（29）And pure water system（30）Water outlet by pipeline respectively with feed bin（3）, crystal temporary storage tank（6）, blending tank（9）、
Filter（4）On water inlet connection, the overheat water system（29）And pure water system（30）Water outlet pipeline on
It is provided with ball valve, the feed bin（3）, crystal temporary storage tank（6）, blending tank（9）, filter（4）On water inlet be both provided with
Pneumatic operated valve, the feed bin（3）, crystal temporary storage tank（6）, blending tank（9）, filter（4）Inside it is both provided with spray tube（27）, spray
Pipe（27）On be provided with spray head（28）, spray tube（27）It is connected with water inlet, the feed bin（3）And filter（4）Interior spray
Head is fan-shaped 60 degree of spray heads, the crystal temporary storage tank（6）And blending tank（9）Interior nozzle is 360 degree of rotary spray heads, in crystalline substance
Body temporary storage tank（6）And blending tank（9）Exhaust-valve is set before the electric control valve of lower section（12）, the spiral pulverizer of low temperature（7）And vibration
Screen-dividing machine（10）Exhaust-valve is set on the pipeline being connected with cyclone separator.
9. collecting crushing packing system automatically according to any dextran large biological molecule finished products of claim 1-8, it is special
Sign is：Control system is further included, the control system includes controller data communication system, the pneumatic operated valve, motorized adjustment
Valve, balanced valve and vacuum detection instrument, air quantity detector are electrically connected with controller data communication system, controller data communication system
System includes detector transmitter and pneumatic operated valve, electric control valve, balance valve actuator, the controller data communication system and behaviour
It is connected as microcomputer, the control system can realize field control, can further realize the online remote control of computer.
10. a kind of dextran large biological molecule finished product collects crushing packing method automatically, it is characterised in that：By claim 1-
9 any automatic crushing packing systems of collecting are completed, and are comprised the following steps：
1000 crystal of dextran large biological molecule into drying machine drying to viscosity be ten thousand centipoises of 5-10, into pendulum coarse powder
Broken machine carries out coarse crushing, and grain diameter 3-4 millimeters after coarse crushing, the particle after coarse crushing enters 0.22 by vacuum feeding pipeline
The sterile stud filter of micron is filtered；
Particle enters in crystal temporary storage tank by Blowing stopper to be stirred, and 120-300 is realized subsequently into the spiral pulverizer of low temperature
Purpose fine crushing, mixing is stirred after cyclone separator is separated into blending tank, then through vibrating screen-dividing machine point
Finished product is obtained after sieve；
（3）Finished product enters package storehouse after entering feeding bin after feeding tube arrival cyclone separator is separated, and is then closing
Metal detector is respectively enterd under the action of wind turbine and automatic packaging machine completes packaging.
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| CN201711395355.5A CN108001744A (en) | 2017-12-21 | 2017-12-21 | Dextran large biological molecule finished product collects crushing packing system and method automatically |
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