CN107982154A - A kind of oral cavity nursing agent with antibacterial whitening function - Google Patents

A kind of oral cavity nursing agent with antibacterial whitening function Download PDF

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Publication number
CN107982154A
CN107982154A CN201711432290.7A CN201711432290A CN107982154A CN 107982154 A CN107982154 A CN 107982154A CN 201711432290 A CN201711432290 A CN 201711432290A CN 107982154 A CN107982154 A CN 107982154A
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parts
oral cavity
agent
cavity nursing
nursing agent
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CN201711432290.7A
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Chinese (zh)
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李文婷
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Individual
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Priority to CN201711432290.7A priority Critical patent/CN107982154A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/28Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)

Abstract

A kind of oral cavity nursing agent with antibacterial whitening function, it includes following components in parts by weight:3.0~4.5 parts of acrylic acid polymer;1.0~3.0 parts of Cocoamidopropyl betaine;1.0~3.0 parts of lauryl sodium sulfate;28~40 parts of moisturizer;0.2~0.5 part of sweetener;0.3~0.7 part of thickener;30~50 parts of rubbing agent;10~25 parts of deionized water;2~8 parts of Flos Camelliae Japonicae extract;3~10 parts of bamboo charcoal;The rubbing agent is longan seed powder and the compounding of wolf's milk powder.By the present invention in that the rubbing agent in being compounded by the use of longan seed powder and wolf's milk powder as oral cavity nursing agent both effectively drives away tooth stain, being avoided that therefore rubbing again causes the phenomenon of bleeding gums, and new hemostatic compositions need not be added, so as to reduce the production cost of oral cavity nursing agent.

Description

A kind of oral cavity nursing agent with antibacterial whitening function
Technical field
The present invention relates to a kind of daily necessities technical field, more particularly to a kind of oral care with antibacterial whitening function Agent.
Background technology
Periodontal disease is common mouth disease, its symptom mainly has bleeding gums, swelling, pain.There is statistics to show, tooth The main reason for all diseases are more than 35 years old crowd's absence of tooth, it is seen that the seriousness of periodontal disease.But since patient is not easy to examine Feel, most people is not aware that oneself is suffered from this disease.Think that people can just suffer from periodontal disease to old many human factor errors, it is actual Upper 5 year old, children can suffer from gingivitis.
Periodontosis is not only to influence the health of tooth, can also systemic health.Periodontosis is to whole body health in recent years Influence caused the concern of people.Bacterial component and bacterial product are easy to be diffused into by oral pocket ulcer surface nearby or remote Every organ, cause or aggravate some general diseases, such as coronary heart disease, low birth weight infant, diabetes, the hair of pulmonary infection disease Hair tonic exhibition, seriously endangers health.It is that can not meet that people improve oral health water to depend merely on stomatological hospital and drug therapy Flat needs, with the use of the oral cavity nursing health products with prevention periodontal disease, periodontal disease is that progressively to be had Imitate what is prevented and control.
In order to preferably prevent periodontal disease, many people's selections are added into rubbing agent in oral cavity nursing agent, but add After entering rubbing agent, people have found the easy bleeding of gum when carrying out oral care using the oral cavity nursing agent with rubbing agent, from And infection is be easy to cause, and in order to stop blooding, also also need to be added into hemostatic compositions in oral cavity nursing agent, be able to must so increase The production cost of oral cavity nursing agent.
The content of the invention
It is an object of the invention to overcome the shortcomings of that the above and defect propose a kind of oral cavity shield with antibacterial whitening function Manage agent.
For this purpose, the present invention uses following technical scheme:
A kind of oral cavity nursing agent with antibacterial whitening function, it includes following components in parts by weight:
3.0~4.5 parts of acrylic acid polymer;
1.0~3.0 parts of Cocoamidopropyl betaine;
1.0~3.0 parts of lauryl sodium sulfate;
28~40 parts of moisturizer;
0.2~0.5 part of sweetener;
0.3~0.7 part of thickener;
15~30 parts of rubbing agent;
10~25 parts of deionized water;
2~8 parts of Flos Camelliae Japonicae extract;
3~10 parts of bamboo charcoal;
The rubbing agent is longan seed powder and the compounding of wolf's milk powder.
Preferably, it further includes 0.02-0.06 portions of preservatives.
Preferably, the preservative is more than one or both of isothiazolinone, nipagin esters, potassium sorbate mixed Compound.
Preferably, the moisturizer compounds for the one or more of which of propane diols, butanediol or glycine betaine.
Preferably, the sweetener is the one or two of saccharin sodium or xylitol.
Preferably, the thickener is sodium carboxymethylcellulose, hydroxyethyl cellulose, the one or more of carbomer answer Match somebody with somebody.
Preferably, longan seed powder, the size of wolf's milk powder are 500-1000 mesh.If the powder used is crossed conference and is made Into laborious when brushing teeth, the inconvenience brushed teeth is caused;If too small, easily remain in the gap of tooth, reduce in friction process Friction, so as to reduce the ability of tooth stain expeling.And longan seed powder, wolf's milk floury texture be not hard, will not cause tooth Tooth damages.
The present invention is used as rubbing agent by adding longan seed powder and wolf's milk powder compounding in oral cavity nursing agent, makes The oral cavity nursing agent of acquisition can quickly remove the dirt for being attached to dental surface, avoid tooth jaundice or long decayed tooth, simultaneously because The effect of friction, the easy bleeding of gum, and longan seed powder, humid euphorbia grass meal have effects that cooling blood and hemostasis in itself, therefore use Oral cavity nursing agent in longan seed powder, wolf's milk powder as rubbing agent not only effectively drives away tooth stain, but can avoid because This, which rubs, causes the phenomenon of bleeding gums, and need not add new hemostatic compositions, so as to reduce the production of oral cavity nursing agent Cost.
Embodiment
Technical scheme is further illustrated below by embodiment.
Embodiment 1
A kind of oral cavity nursing agent with antibacterial whitening function, it includes following components in parts by weight:
3.0 parts of acrylic acid polymer;
1.5 parts of Cocoamidopropyl betaine;
1.0 parts of lauryl sodium sulfate;
28 parts of glycine betaine;
0.2 part of saccharin sodium;
0.3 part of sodium carboxymethylcellulose;
Longan seed powder, wolf's milk powder:Additive amount is added by table 1;
0.02 part of nipagin esters;
10 parts of deionized water;
2 parts of Flos Camelliae Japonicae extract;
3 parts of bamboo charcoal.
Table 1 is influence of the additive amount of rubbing agent to expeling tooth stain ability
It can be obtained by table 1, after having used the rubbing agent of longan seed powder and wolf's milk powder as compounding, drive away tooth stain Ability enhance, and either can reach 91 for the expeling dirt ability of the tooth stain that has been aged 15 days or 30 days More than, and the compounding proportioning that optimal expeling soils are the longan seed powder and wolf's milk powder used is 2:1.
In order to test the effect of the present embodiment 1-1 to embodiment 1-3 obtains the hemostasis aspect of oral cavity nursing agent, mouse is carried out Clinical hemostasis experiment mice clinical hemostasis experiment.
Clinical trial of stopping blooding uses blank lotion, Colgate-Palmolive toothpaste, Crest toothpaste, embodiment 1-1 into embodiment 1-3 Oral cavity nursing agent as examination thing sample.
Carried out using hemostasis observational technique is damaged to mouse liver local woanded surface.Take the kunming mice 108 of health, weight 18~22g, male and female dual-purpose.After anesthetized mice, liver is cut in left lobe of liver with operating scissors and be about 0.5cm, wide about 0.5cm, it is high about 0.5cm, after the blood for wiping ejection, immediately in situation portion spreading thing sample 0.5g to be tried, oppresses 1min, after 1min with 200g counterweights Counterweight is removed, haemostatic effect is observed, untill not bleeding.Such as still bleeding, add to apply and pressurize after thing sample is tried, observed every 30s Once, bleeding stopping period is recorded, is such as no more than 3min, being then denoted as to stop blooding;Such as fail to stop blooding more than 3min, be then denoted as and fail to stop Blood, experimental result are shown in Table 2.
The clinical blood coagulation hemostasis experimental result of 2 mouse of table
Try thing sample Experiment number Bleeding stopping period
Blank lotion 18 > 3
Colgate-Palmolive toothpaste 18 2.65±0.22
Crest toothpaste 18 2.51±0.18
The oral cavity nursing agent of embodiment 1-1 18 2.17±0.15
The oral cavity nursing agent of embodiment 1-2 18 2.11±0.13
The oral cavity nursing agent of embodiment 1-3 18 2.06±0.12
As shown in Table 2, the oral cavity nursing agent of embodiment 1-1 to embodiment 1-3 is to mouse liver local woanded surface bleeding due to trauma There is obvious blood coagulation haemostatic effect.
Embodiment 2
A kind of oral cavity nursing agent with antibacterial whitening function, it includes following components in parts by weight:
4.5 parts of acrylic acid polymer;
3.5 parts of Cocoamidopropyl betaine;
3.0 parts of lauryl sodium sulfate;
30 parts of butanediol;
0.3 part of saccharin sodium;
0.7 part of hydroxyethyl cellulose;
17 parts of longan seed powder, 8 parts of wolf's milk powder;
0.06 part of potassium sorbate;
20 parts of deionized water;
7 parts of Flos Camelliae Japonicae extract;
5 parts of bamboo charcoal.
The oral cavity nursing agent of the present embodiment is 97/8 day for the expeling ability of the tooth stain of ageing 15 days;For ageing The expeling ability of the tooth stain of 30 days is 91/12 day.
Embodiment 3
A kind of oral cavity nursing agent with antibacterial whitening function, it includes following components in parts by weight:
3.5 parts of acrylic acid polymer;
2.5 parts of Cocoamidopropyl betaine;
2.0 parts of lauryl sodium sulfate;
32 parts of propane diols;
0.5 part of xylitol;
0.6 part of carbomer;
13.5 parts of longan seed powder, wolf's milk powder 11.5;
0.04 part of isothiazolinone;
15 parts of deionized water;
8 parts of Flos Camelliae Japonicae extract;
6 parts of bamboo charcoal.
The oral cavity nursing agent of the present embodiment is 97/8 day for the expeling ability of the tooth stain of ageing 15 days;For ageing The expeling ability of the tooth stain of 30 days is 92/11 day.
Embodiment 4
A kind of oral cavity nursing agent with antibacterial whitening function, it includes following components in parts by weight:
4 parts of acrylic acid polymer;
2.6 parts of Cocoamidopropyl betaine;
1.5 parts of lauryl sodium sulfate;
35 parts of glycine betaine;
0.3 part of saccharin sodium;
0.2 part of sodium carboxymethylcellulose, 0.2 part of hydroxyethyl cellulose, 0.3 part of carbomer;
8 parts of longan seed powder 11, wolf's milk powder;
Nipagin esters 0.25,0.15 part of potassium sorbate;
22 parts of deionized water;
6.5 parts of Flos Camelliae Japonicae extract;
10 parts of bamboo charcoal.
The oral cavity nursing agent of the present embodiment is 96/8 day for the expeling ability of the tooth stain of ageing 15 days;For ageing The expeling ability of the tooth stain of 30 days is 92/19 day.
Embodiment 5
A kind of oral cavity nursing agent with antibacterial whitening function, it includes following components in parts by weight:
4.5 parts of acrylic acid polymer;
3.2 parts of Cocoamidopropyl betaine;
2.5 parts of lauryl sodium sulfate;
30 parts of butanediol;
0.4 part of xylitol;
0.4 part of sodium carboxymethylcellulose, 0.2 part of hydroxyethyl cellulose;
9 parts of longan seed powder, 7 parts of wolf's milk powder;
0.02 part of isothiazolinone, 0.03 part of nipagin esters;
14 parts of deionized water;
7.5 parts of Flos Camelliae Japonicae extract;
4 parts of bamboo charcoal.
The oral cavity nursing agent of the present embodiment is 96/9 day for the expeling ability of the tooth stain of ageing 15 days;For ageing The expeling ability of the tooth stain of 30 days is 91/18 day.
Embodiment 6
A kind of oral cavity nursing agent with antibacterial whitening function, it includes following components in parts by weight:
3.5 parts of acrylic acid polymer;
2.8 parts of Cocoamidopropyl betaine;
2 parts of lauryl sodium sulfate;
38 parts of propane diols;
0.3 part of xylitol, 0.2 part of saccharin sodium;
0.1 part of sodium carboxymethylcellulose, 0.3 part of carbomer;
10 parts of longan seed powder, 11.5 parts of wolf's milk powder;
0.05 part of isothiazolinone;
17.5 parts of deionized water;
6 parts of Flos Camelliae Japonicae extract;
9 parts of bamboo charcoal.
The oral cavity nursing agent of the present embodiment is 97/9 day for the expeling ability of the tooth stain of ageing 15 days;For ageing The expeling ability of the tooth stain of 30 days is 91/13 day.
Embodiment 7
A kind of oral cavity nursing agent with antibacterial whitening function, it includes following components in parts by weight:
4.1 parts of acrylic acid polymer;
3.2 parts of Cocoamidopropyl betaine;
2.7 parts of lauryl sodium sulfate;
10 parts of propane diols, 21 parts of glycine betaine;
0.3 part of saccharin sodium;
0.25 part of hydroxyethyl cellulose, 0.35 part of carbomer;
11 parts of longan seed powder, 11 parts of wolf's milk powder;
0.01 part of isothiazolinone, 0.01 part of potassium sorbate;
14.5 parts of deionized water;
3 parts of Flos Camelliae Japonicae extract;
5 parts of bamboo charcoal.
The oral cavity nursing agent of the present embodiment is 97/7 day for the expeling ability of the tooth stain of ageing 15 days;For ageing The expeling ability of the tooth stain of 30 days is 92/12 day.
Embodiment 8
A kind of oral cavity nursing agent with antibacterial whitening function, it includes following components in parts by weight:
3.8 parts of acrylic acid polymer;
2.1 parts of Cocoamidopropyl betaine;
2.5 parts of lauryl sodium sulfate;
24 parts of butanediol, 10 parts of glycine betaine;
0.3 part of xylitol, 0.1 part of saccharin sodium;
0.55 part of hydroxyethyl cellulose;
9 parts of longan seed powder, 15 parts of wolf's milk powder;
0.01 part of isothiazolinone, 0.02 part of nipagin esters;
20.5 parts of deionized water;
2.5 parts of Flos Camelliae Japonicae extract;
3.5 parts of bamboo charcoal;
The oral cavity nursing agent of the present embodiment is 97/10 day for the expeling ability of the tooth stain of ageing 15 days;For old The expeling ability for changing the tooth stain of 30 days is 91/17 day.
Embodiment 9
A kind of oral cavity nursing agent with antibacterial whitening function, it includes following components in parts by weight:
3.2 parts of acrylic acid polymer;
2.7 parts of Cocoamidopropyl betaine;
1.0 parts of lauryl sodium sulfate;
28 parts of propane diols, butanediol or glycine betaine;
0.25 part of xylitol;
0.35 part of sodium carboxymethylcellulose;
8 parts of longan seed powder, 10 parts of wolf's milk powder;
0.02 part of isothiazolinone, 0.01 part of nipagin esters, 0.03 part of potassium sorbate;
15 parts of deionized water;
5.5 parts of Flos Camelliae Japonicae extract;
8.5 parts of bamboo charcoal.
The oral cavity nursing agent of the present embodiment is 97/9 day for the expeling ability of the tooth stain of ageing 15 days;For ageing The expeling ability of the tooth stain of 30 days is 91/15 day.
Embodiment 10
A kind of oral cavity nursing agent with antibacterial whitening function, it includes following components in parts by weight:
3.6 parts of acrylic acid polymer;
3.3 parts of Cocoamidopropyl betaine;
1.8 parts of lauryl sodium sulfate;
14 parts of propane diols, 23 parts of butanediol;
0.2 part of xylitol, 0.25 part of saccharin sodium;
0.5 part of carbomer;
12 parts of longan seed powder, 8 parts of wolf's milk powder;
0.01 part of potassium sorbate, 0.02 part of isothiazolinone;
25 parts of deionized water;
4 parts of Flos Camelliae Japonicae extract;
4.5 parts of bamboo charcoal.
The oral cavity nursing agent of the present embodiment is 98/8 day for the expeling ability of the tooth stain of ageing 15 days;For ageing The expeling ability of the tooth stain of 30 days is 92/12 day.
Above in association with the specific embodiment technical principle that the invention has been described.These descriptions are intended merely to explain the present invention's Principle, and limiting the scope of the invention cannot be construed in any way.Based on explanation herein, the technology of this area Personnel would not require any inventive effort the other embodiments that can associate the present invention, these modes are fallen within Within protection scope of the present invention.

Claims (7)

1. a kind of oral cavity nursing agent with antibacterial whitening function, it is characterised in that it includes following components in parts by weight:
3.0~4.5 parts of acrylic acid polymer;
1.0~3.0 parts of Cocoamidopropyl betaine;
1.0~3.0 parts of lauryl sodium sulfate;
28~40 parts of moisturizer;
0.2~0.5 part of sweetener;
0.3~0.7 part of thickener;
30~50 parts of rubbing agent;
10~25 parts of deionized water;
2~8 parts of Flos Camelliae Japonicae extract;
3~10 parts of bamboo charcoal;
The rubbing agent is longan seed powder and the compounding of wolf's milk powder.
A kind of 2. oral cavity nursing agent with antibacterial whitening function according to claim 1, it is characterised in that:It is further included 0.02-0.06 portions of preservatives.
A kind of 3. oral cavity nursing agent with antibacterial whitening function according to claim 2, it is characterised in that:The anti-corrosion Agent is mixture more than one or both of isothiazolinone, nipagin esters, potassium sorbate.
A kind of 4. oral cavity nursing agent with antibacterial whitening function according to claim 1, it is characterised in that:The moisturizing Agent compounds for the one or more of which of propane diols, butanediol or glycine betaine.
A kind of 5. oral cavity nursing agent with antibacterial whitening function according to claim 1, it is characterised in that:The sweet taste Agent is the one or two of saccharin sodium or xylitol.
A kind of 6. oral cavity nursing agent with antibacterial whitening function according to claim 1, it is characterised in that:The thickening Agent is sodium carboxymethylcellulose, one or more compoundings of hydroxyethyl cellulose, carbomer.
A kind of 7. oral cavity nursing agent with antibacterial whitening function according to claim 1, it is characterised in that:The longan Core powder, the size of wolf's milk powder are 500-1000 mesh.
CN201711432290.7A 2017-12-26 2017-12-26 A kind of oral cavity nursing agent with antibacterial whitening function Withdrawn CN107982154A (en)

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Application Number Priority Date Filing Date Title
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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104248571A (en) * 2014-09-19 2014-12-31 云南七丹药业股份有限公司 Purely natural plant-containing abradant toothpaste and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104248571A (en) * 2014-09-19 2014-12-31 云南七丹药业股份有限公司 Purely natural plant-containing abradant toothpaste and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
熊辅信,等: "《中药现代研究荟萃》", 31 May 2002, 云南科技出版社 *
老中医养生堂: "《本草纲目中药草使用图鉴》", 30 April 2016, 福建科学技术出版社 *

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Application publication date: 20180504