CN107929165A - A kind of oral cavity nursing agent with anti-inflammatory effect - Google Patents
A kind of oral cavity nursing agent with anti-inflammatory effect Download PDFInfo
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- CN107929165A CN107929165A CN201711434345.8A CN201711434345A CN107929165A CN 107929165 A CN107929165 A CN 107929165A CN 201711434345 A CN201711434345 A CN 201711434345A CN 107929165 A CN107929165 A CN 107929165A
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- oral cavity
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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Abstract
A kind of oral cavity nursing agent with anti-inflammatory effect, it includes following components in parts by weight：0.5~2 part of Irish moss；1.0~3.0 parts of Cocoamidopropyl betaine；1.0~3.0 parts of lauryl sodium sulfate；28~40 parts of moisturizer；0.2~0.5 part of sweetener；0.3~0.7 part of thickener；30~50 parts of rubbing agent；10~25 parts of deionized water；7~10 parts of marigold；The rubbing agent is longan seed powder and the compounding of wolf's milk powder.By the present invention in that the rubbing agent in being compounded by the use of longan seed powder and wolf's milk powder as oral cavity nursing agent both effectively drives away tooth stain, being avoided that therefore rubbing again causes the phenomenon of bleeding gums, and new hemostatic compositions need not be added, so as to reduce the production cost of oral cavity nursing agent.
Description
Technical field
The present invention relates to a kind of daily necessities technical field, more particularly to a kind of oral cavity nursing agent with anti-inflammatory effect.
Background technology
Periodontal disease is common mouth disease, its symptom mainly has bleeding gums, swelling, pain.There is statistics to show, tooth
The main reason for all diseases are more than 35 years old crowd's absence of tooth, it is seen that the seriousness of periodontal disease.But since patient is not easy to examine
Feel, most people is not aware that oneself is suffered from this disease.Think that people can just suffer from periodontal disease to old many human factor errors, it is actual
Upper 5 year old, children can suffer from gingivitis.
Periodontosis is not only to influence the health of tooth, can also systemic health.Periodontosis is to whole body health in recent years
Influence caused the concern of people.Bacterial component and bacterial product are easy to be diffused into by oral pocket ulcer surface nearby or remote
Every organ, cause or aggravate some general diseases, such as coronary heart disease, low birth weight infant, diabetes, the hair of pulmonary infection disease
Hair tonic exhibition, seriously endangers health.It is that can not meet that people improve oral health water to depend merely on stomatological hospital and drug therapy
Flat needs, with the use of the oral cavity nursing health products with prevention periodontal disease, periodontal disease is that progressively to be had
Imitate what is prevented and control.
In order to preferably prevent periodontal disease, many people's selections are added into rubbing agent in oral cavity nursing agent, but add
After entering rubbing agent, people have found the easy bleeding of gum when carrying out oral care using the oral cavity nursing agent with rubbing agent, from
And infection is be easy to cause, and in order to stop blooding, also also need to be added into hemostatic compositions in oral cavity nursing agent, be able to must so increase
The production cost of oral cavity nursing agent.
The content of the invention
It is an object of the invention to overcome the shortcomings of that the above and defect propose a kind of oral cavity nursing agent with anti-inflammatory effect.
For this purpose, the present invention uses following technical scheme：
A kind of oral cavity nursing agent with anti-inflammatory effect, it includes following components in parts by weight：
0.5~2 part of Irish moss；
1.0~3.0 parts of Cocoamidopropyl betaine；
1.0~3.0 parts of lauryl sodium sulfate；
28~40 parts of moisturizer；
0.2~0.5 part of sweetener；
0.3~0.7 part of thickener；
15~30 parts of rubbing agent；
10~25 parts of deionized water；
7~10 parts of marigold；
The rubbing agent is longan seed powder and the compounding of wolf's milk powder.
Preferably, it further includes 0.02-0.06 portions of preservatives.
Preferably, the preservative is more than one or both of isothiazolinone, nipagin esters, potassium sorbate mixed
Compound.
Preferably, the moisturizer compounds for the one or more of which of propane diols, butanediol or glycine betaine.
Preferably, the sweetener is the one or two of saccharin sodium or xylitol.
Preferably, the thickener is sodium carboxymethylcellulose, hydroxyethyl cellulose, the one or more of carbomer answer
Match somebody with somebody.
Preferably, longan seed powder, the size of wolf's milk powder are 500-1000 mesh.If the powder used is crossed conference and is made
Into laborious when brushing teeth, the inconvenience brushed teeth is caused；If too small, easily remain in the gap of tooth, reduce in friction process
Friction, so as to reduce the ability of tooth stain expeling.And longan seed powder, wolf's milk floury texture be not hard, will not cause tooth
Tooth damages.
The present invention is used as rubbing agent by adding longan seed powder and wolf's milk powder compounding in oral cavity nursing agent, makes
The oral cavity nursing agent of acquisition can quickly remove the dirt for being attached to dental surface, avoid tooth jaundice or long decayed tooth, simultaneously because
The effect of friction, the easy bleeding of gum, and longan seed powder, humid euphorbia grass meal have effects that cooling blood and hemostasis in itself, therefore use
Oral cavity nursing agent in longan seed powder, wolf's milk powder as rubbing agent not only effectively drives away tooth stain, but can avoid because
This, which rubs, causes the phenomenon of bleeding gums, and need not add new hemostatic compositions, so as to reduce the production of oral cavity nursing agent
Cost.
Embodiment
Technical scheme is further illustrated below by embodiment.
Embodiment 1
A kind of oral cavity nursing agent with anti-inflammatory effect, it includes following components in parts by weight：
0.5 part of Irish moss；
1.5 parts of Cocoamidopropyl betaine；
1.0 parts of lauryl sodium sulfate；
28 parts of glycine betaine；
0.2 part of saccharin sodium；
0.3 part of sodium carboxymethylcellulose；
Longan seed powder, wolf's milk powder：Additive amount is added by table 1；
0.02 part of nipagin esters；
10 parts of deionized water；
7 parts of marigold.
Table 1 is influence of the additive amount of rubbing agent to expeling tooth stain ability
It can be obtained by table 1, after having used the rubbing agent of longan seed powder and wolf's milk powder as compounding, drive away tooth stain
Ability enhance, and either can reach 91 for the expeling dirt ability of the tooth stain that has been aged 15 days or 30 days
More than, and the compounding proportioning that optimal expeling soils are the longan seed powder and wolf's milk powder used is 2:1.
In order to test the effect of the present embodiment 1-1 to embodiment 1-3 obtains the hemostasis aspect of oral cavity nursing agent, mouse is carried out
Clinical hemostasis experiment mice clinical hemostasis experiment.
Clinical trial of stopping blooding uses blank lotion, Colgate-Palmolive toothpaste, Crest toothpaste, embodiment 1-1 into embodiment 1-3
Oral cavity nursing agent as examination thing sample.
Carried out using hemostasis observational technique is damaged to mouse liver local woanded surface.Take the kunming mice 108 of health, weight
18~22g, male and female dual-purpose.After anesthetized mice, liver is cut in left lobe of liver with operating scissors and be about 0.5cm, wide about 0.5cm, it is high about
0.5cm, after the blood for wiping ejection, immediately in situation portion spreading thing sample 0.5g to be tried, oppresses 1min, after 1min with 200g counterweights
Counterweight is removed, haemostatic effect is observed, untill not bleeding.Such as still bleeding, add to apply and pressurize after thing sample is tried, observed every 30s
Once, bleeding stopping period is recorded, is such as no more than 3min, being then denoted as to stop blooding；Such as fail to stop blooding more than 3min, be then denoted as and fail to stop
Blood, experimental result are shown in Table 2.
The clinical blood coagulation hemostasis experimental result of 2 mouse of table
| Try thing sample | Experiment number | Bleeding stopping period |
| Blank lotion | 18 | ＞ 3 |
| Colgate-Palmolive toothpaste | 18 | 2.65±0.22 |
| Crest toothpaste | 18 | 2.51±0.18 |
| The oral cavity nursing agent of embodiment 1-1 | 18 | 2.17±0.15 |
| The oral cavity nursing agent of embodiment 1-2 | 18 | 2.11±0.13 |
| The oral cavity nursing agent of embodiment 1-3 | 18 | 2.06±0.12 |
As shown in Table 2, the oral cavity nursing agent of embodiment 1-1 to embodiment 1-3 is to mouse liver local woanded surface bleeding due to trauma
There is obvious blood coagulation haemostatic effect.
Embodiment 2
A kind of oral cavity nursing agent with anti-inflammatory effect, it includes following components in parts by weight：
1.2 parts of Irish moss；
3.5 parts of Cocoamidopropyl betaine；
3.0 parts of lauryl sodium sulfate；
30 parts of butanediol；
0.3 part of saccharin sodium；
0.7 part of hydroxyethyl cellulose；
17 parts of longan seed powder, 8 parts of wolf's milk powder；
0.06 part of potassium sorbate；
20 parts of deionized water；
7.5 parts of marigold.
The oral cavity nursing agent of the present embodiment is 97/8 day for the expeling ability of the tooth stain of ageing 15 days；
Expeling ability for the ageing tooth stain of 30 days is 91/12 day.
Embodiment 3
A kind of oral cavity nursing agent with anti-inflammatory effect, it includes following components in parts by weight：
1 part of Irish moss；
2.5 parts of Cocoamidopropyl betaine；
2.0 parts of lauryl sodium sulfate；
32 parts of propane diols；
0.5 part of xylitol；
0.6 part of carbomer；
13.5 parts of longan seed powder, wolf's milk powder 11.5；
0.04 part of isothiazolinone；
15 parts of deionized water；
10 parts of marigold.
The oral cavity nursing agent of the present embodiment is 97/8 day for the expeling ability of the tooth stain of ageing 15 days；
Expeling ability for the ageing tooth stain of 30 days is 92/11 day.
Embodiment 4
A kind of oral cavity nursing agent with anti-inflammatory effect, it includes following components in parts by weight：
1.75 parts of Irish moss；
2.6 parts of Cocoamidopropyl betaine；
1.5 parts of lauryl sodium sulfate；
35 parts of glycine betaine；
0.3 part of saccharin sodium；
0.2 part of sodium carboxymethylcellulose, 0.2 part of hydroxyethyl cellulose, 0.3 part of carbomer；
8 parts of longan seed powder 11, wolf's milk powder；
Nipagin esters 0.25,0.15 part of potassium sorbate；
22 parts of deionized water；
9 parts of marigold.
The oral cavity nursing agent of the present embodiment is 96/8 day for the expeling ability of the tooth stain of ageing 15 days；
Expeling ability for the ageing tooth stain of 30 days is 92/19 day.
Embodiment 5
A kind of oral cavity nursing agent with anti-inflammatory effect, it includes following components in parts by weight：
1.6 parts of Irish moss；
3.2 parts of Cocoamidopropyl betaine；
2.5 parts of lauryl sodium sulfate；
30 parts of butanediol；
0.4 part of xylitol；
0.4 part of sodium carboxymethylcellulose, 0.2 part of hydroxyethyl cellulose；
9 parts of longan seed powder, 7 parts of wolf's milk powder；
0.02 part of isothiazolinone, 0.03 part of nipagin esters；
14 parts of deionized water；
9.5 parts of marigold.
The oral cavity nursing agent of the present embodiment is 96/9 day for the expeling ability of the tooth stain of ageing 15 days；
Expeling ability for the ageing tooth stain of 30 days is 91/18 day.
Embodiment 6
A kind of oral cavity nursing agent with anti-inflammatory effect, it includes following components in parts by weight：
1.5 parts of Irish moss；
2.8 parts of Cocoamidopropyl betaine；
2 parts of lauryl sodium sulfate；
38 parts of propane diols；
0.3 part of xylitol, 0.2 part of saccharin sodium；
0.1 part of sodium carboxymethylcellulose, 0.3 part of carbomer；
10 parts of longan seed powder, 11.5 parts of wolf's milk powder；
0.05 part of isothiazolinone；
17.5 parts of deionized water；
8.5 parts of marigold.
The oral cavity nursing agent of the present embodiment is 97/9 day for the expeling ability of the tooth stain of ageing 15 days；For ageing
The expeling ability of the tooth stain of 30 days is 91/13 day.
Embodiment 7
A kind of oral cavity nursing agent with anti-inflammatory effect, it includes following components in parts by weight：
2 parts of Irish moss；
3.2 parts of Cocoamidopropyl betaine；
2.7 parts of lauryl sodium sulfate；
10 parts of propane diols, 21 parts of glycine betaine；
0.3 part of saccharin sodium；
0.25 part of hydroxyethyl cellulose, 0.35 part of carbomer；
11 parts of longan seed powder, 11 parts of wolf's milk powder；
0.01 part of isothiazolinone, 0.01 part of potassium sorbate；
14.5 parts of deionized water；
8.5 parts of marigold.
The oral cavity nursing agent of the present embodiment is 97/7 day for the expeling ability of the tooth stain of ageing 15 days；For ageing
The expeling ability of the tooth stain of 30 days is 92/12 day.
Embodiment 8
A kind of oral cavity nursing agent with anti-inflammatory effect, it includes following components in parts by weight：
1.8 parts of Irish moss；
2.1 parts of Cocoamidopropyl betaine；
2.5 parts of lauryl sodium sulfate；
24 parts of butanediol, 10 parts of glycine betaine；
0.3 part of xylitol, 0.1 part of saccharin sodium；
0.55 part of hydroxyethyl cellulose；
9 parts of longan seed powder, 15 parts of wolf's milk powder；
0.01 part of isothiazolinone, 0.02 part of nipagin esters；
20.5 parts of deionized water；
9.5 parts of marigold.
The oral cavity nursing agent of the present embodiment is 97/10 day for the expeling ability of the tooth stain of ageing 15 days；For old
The expeling ability for changing the tooth stain of 30 days is 91/17 day.
Embodiment 9
A kind of oral cavity nursing agent with anti-inflammatory effect, it includes following components in parts by weight：
0.9 part of Irish moss；
2.7 parts of Cocoamidopropyl betaine；
1.0 parts of lauryl sodium sulfate；
28 parts of propane diols, butanediol or glycine betaine；
0.25 part of xylitol；
0.35 part of sodium carboxymethylcellulose；
8 parts of longan seed powder, 10 parts of wolf's milk powder；
0.02 part of isothiazolinone, 0.01 part of nipagin esters, 0.03 part of potassium sorbate；
15 parts of deionized water；
7 parts of marigold.
The oral cavity nursing agent of the present embodiment is 97/9 day for the expeling ability of the tooth stain of ageing 15 days；For ageing
The expeling ability of the tooth stain of 30 days is 91/15 day.
Embodiment 10
A kind of oral cavity nursing agent with anti-inflammatory effect, it includes following components in parts by weight：
0.8 part of Irish moss；
3.3 parts of Cocoamidopropyl betaine；
1.8 parts of lauryl sodium sulfate；
14 parts of propane diols, 23 parts of butanediol；
0.2 part of xylitol, 0.25 part of saccharin sodium；
0.5 part of carbomer；
12 parts of longan seed powder, 8 parts of wolf's milk powder；
0.01 part of potassium sorbate, 0.02 part of isothiazolinone；
25 parts of deionized water；
10 parts of marigold.
The oral cavity nursing agent of the present embodiment is 98/8 day for the expeling ability of the tooth stain of ageing 15 days；For ageing
The expeling ability of the tooth stain of 30 days is 92/12 day.
Above in association with the specific embodiment technical principle that the invention has been described.These descriptions are intended merely to explain the present invention's
Principle, and limiting the scope of the invention cannot be construed in any way.Based on explanation herein, the technology of this area
Personnel would not require any inventive effort the other embodiments that can associate the present invention, these modes are fallen within
Within protection scope of the present invention.
Claims (7)
1. a kind of oral cavity nursing agent with anti-inflammatory effect, it is characterised in that it includes following components in parts by weight：
0.5~2 part of Irish moss；
1.0~3.0 parts of Cocoamidopropyl betaine；
1.0~3.0 parts of lauryl sodium sulfate；
28~40 parts of moisturizer；
0.2~0.5 part of sweetener；
0.3~0.7 part of thickener；
30~50 parts of rubbing agent；
10~25 parts of deionized water；
7~10 parts of marigold；
The rubbing agent is longan seed powder and the compounding of wolf's milk powder.
A kind of 2. oral cavity nursing agent with anti-inflammatory effect according to claim 1, it is characterised in that：It is further included
0.02-0.06 portions of preservatives.
A kind of 3. oral cavity nursing agent with anti-inflammatory effect according to claim 2, it is characterised in that：The preservative is
Mixture more than one or both of isothiazolinone, nipagin esters, potassium sorbate.
A kind of 4. oral cavity nursing agent with anti-inflammatory effect according to claim 1, it is characterised in that：The moisturizer is
The one or more of which compounding of propane diols, butanediol or glycine betaine.
A kind of 5. oral cavity nursing agent with anti-inflammatory effect according to claim 1, it is characterised in that：The sweetener is
The one or two of saccharin sodium or xylitol.
A kind of 6. oral cavity nursing agent with anti-inflammatory effect according to claim 1, it is characterised in that：The thickener is
Sodium carboxymethylcellulose, hydroxyethyl cellulose, one or more compoundings of carbomer.
A kind of 7. oral cavity nursing agent with anti-inflammatory effect according to claim 1, it is characterised in that：The longan seed powder
End, the size of wolf's milk powder are 500-1000 mesh.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711434345.8A CN107929165A (en) | 2017-12-26 | 2017-12-26 | A kind of oral cavity nursing agent with anti-inflammatory effect |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711434345.8A CN107929165A (en) | 2017-12-26 | 2017-12-26 | A kind of oral cavity nursing agent with anti-inflammatory effect |
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| Publication Number | Publication Date |
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| CN107929165A true CN107929165A (en) | 2018-04-20 |
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|---|---|---|---|
| CN201711434345.8A Withdrawn CN107929165A (en) | 2017-12-26 | 2017-12-26 | A kind of oral cavity nursing agent with anti-inflammatory effect |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104248571A (en) * | 2014-09-19 | 2014-12-31 | 云南七丹药业股份有限公司 | Purely natural plant-containing abradant toothpaste and preparation method thereof |
-
2017
- 2017-12-26 CN CN201711434345.8A patent/CN107929165A/en not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104248571A (en) * | 2014-09-19 | 2014-12-31 | 云南七丹药业股份有限公司 | Purely natural plant-containing abradant toothpaste and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 熊辅信，等: "《中药现代研究荟萃》", 31 May 2002, 云南科技出版社 * |
| 老中医养生堂: "《本草纲目中药草使用图鉴》", 30 April 2016, 福建科学技术出版社 * |
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