CN108042424A - A kind of antianaphylactic hemostasis oral cavity nursing agent - Google Patents
A kind of antianaphylactic hemostasis oral cavity nursing agent Download PDFInfo
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- CN108042424A CN108042424A CN201711434849.XA CN201711434849A CN108042424A CN 108042424 A CN108042424 A CN 108042424A CN 201711434849 A CN201711434849 A CN 201711434849A CN 108042424 A CN108042424 A CN 108042424A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
A kind of antianaphylactic hemostasis oral cavity nursing agent includes following components in parts by weight：0.5~2 part of Irish moss；1.5~3.5 parts of Cocoamidopropyl betaine；1.0~3.0 parts of lauryl sodium sulfate；28~40 parts of moisturizer；0.2~0.5 part of sweetener；0.3~0.7 part of thickener；30~50 parts of rubbing agent；10~25 parts of deionized water；4~8 parts of Honegsukle flower P.E；7~12 parts of Lotus Plumule P.E.；3~8 parts of peppermint extract liquor；3~7 parts of Flos Chrysanthemi Indici extract；The rubbing agent is longan seed powder and the compounding of Herba Euphorbiae Humifusae powder.By the present invention in that the rubbing agent by the use of longan seed powder and compounding as the oral cavity nursing agent of Herba Euphorbiae Humifusae powder both effectively drives away tooth stain, the phenomenon that therefore friction causes bleeding gums is avoided that again, and new hemostatic compositions need not be added, so as to reduce the production cost of oral cavity nursing agent.
Description
Technical field
The present invention relates to a kind of daily necessities technical field more particularly to a kind of antianaphylactic hemostasis oral cavity nursing agents.
Background technology
Periodontal disease is common mouth disease, and symptom mainly has bleeding gums, swelling, pain.There is statistics to show, tooth
The main reason for all diseases are 35 years old or more crowd's absence of tooth, it is seen that the seriousness of periodontal disease.But since patient is not easy to examine
Feel, most people is not aware that oneself is suffered from this disease.Think that people can just suffer from periodontal disease to old many human factor errors, it is actual
Upper 5 year old, children can suffer from gingivitis.
Periodontosis is not only to influence the health of tooth, can also systemic health.Periodontosis is to whole body health in recent years
Influence caused the concern of people.Bacterial component and bacterial product are easy to be diffused by oral pocket ulcer surface nearby or remote
Every organ, cause or aggravate some general diseases, such as coronary heart disease, low birth weight infant, diabetes, the hair of pulmonary infection disease
Hair tonic exhibition seriously endangers health.It is that can not meet people to improve oral health water to depend merely on stomatological hospital and drug therapy
Flat needs, with the use of the oral cavity nursing health products with prevention periodontal disease, periodontal disease is that progressively to be had
Imitate what is prevented and control.
In order to preferably prevent periodontal disease, many persons select and rubbing agent are added into oral cavity nursing agent, but add
After entering rubbing agent, people have found the easy bleeding of gum when the oral cavity nursing agent with rubbing agent is used to carry out oral care, from
And infection is be easy to cause, and in order to stop blooding, it also also needs to be added into hemostatic compositions in oral cavity nursing agent, must can so increase
The production cost of oral cavity nursing agent.
The content of the invention
It is an object of the invention to propose a kind of antianaphylactic hemostasis oral cavity nursing agent with defect more than overcoming the shortcomings of.
For this purpose, the present invention uses following technical scheme：
A kind of antianaphylactic hemostasis oral cavity nursing agent includes following components in parts by weight：
0.5~2 part of Irish moss；
1.5~3.5 parts of Cocoamidopropyl betaine；
1.0~3.0 parts of lauryl sodium sulfate；
28~40 parts of moisturizer；
0.2~0.5 part of sweetener；
0.3~0.7 part of thickener；
15~30 parts of rubbing agent；
10~25 parts of deionized water；
4~8 parts of Honegsukle flower P.E；
7~12 parts of Lotus Plumule P.E.；
3~8 parts of peppermint extract liquor；
3~7 parts of Flos Chrysanthemi Indici extract；
The rubbing agent is longan seed powder and the compounding of Herba Euphorbiae Humifusae powder.
Preferably, 0.02-0.06 portions of preservatives are further included.
Preferably, the preservative is more than one or both of isothiazolinone, paraben esters, potassium sorbate mixed
Close object.
Preferably, the moisturizer compounds for the one or more of which of propylene glycol, butanediol or glycine betaine.
Preferably, the sweetener is the one or two of saccharin sodium or xylitol.
Preferably, the thickener is sodium carboxymethylcellulose, hydroxyethyl cellulose, the one or more of carbomer are answered
Match somebody with somebody.
Preferably, longan seed powder, the size of Herba Euphorbiae Humifusae powder are 500-1000 mesh.If the powder used is crossed conference and is made
Into laborious when brushing teeth, the inconvenience brushed teeth is caused；It if too small, easily remains in the gap of tooth, reduces in friction process
Friction, so as to reduce the ability of tooth stain expeling.And longan seed powder, Herba Euphorbiae Humifusae floury texture be not hard, will not cause tooth
Tooth damages.
The present invention is used as rubbing agent by adding the compounding of longan seed powder and Herba Euphorbiae Humifusae powder in oral cavity nursing agent,
The oral cavity nursing agent of acquisition is enable quickly to remove the dirt for being attached to dental surface, tooth jaundice or length is avoided to decay tooth, while by
In the effect of friction, the easy bleeding of gum, and longan seed powder, humid euphorbia grass meal have effects that cooling blood and hemostasis in itself, therefore make
Not only effectively drive away tooth stain by the use of the oral cavity nursing agent of longan seed powder and compounding as the rubbing agent of Herba Euphorbiae Humifusae powder, but also can
The phenomenon that therefore friction causes bleeding gums is avoided, and new hemostatic compositions need not be added, so as to reduce oral cavity nursing agent
Production cost.
Specific embodiment
The technical solution further illustrated the present invention below by specific embodiment.
Embodiment 1
A kind of antianaphylactic hemostasis oral cavity nursing agent includes following components in parts by weight：
0.5 part of Irish moss；
1.5 parts of Cocoamidopropyl betaine；
1.0 parts of lauryl sodium sulfate；
28 parts of glycine betaine；
0.2 part of saccharin sodium；
0.3 part of sodium carboxymethylcellulose；
Longan seed powder, Herba Euphorbiae Humifusae powder：Additive amount is added by table 1；
0.02 part of paraben esters；
10 parts of deionized water；
4 parts of Honegsukle flower P.E；
7 parts of Lotus Plumule P.E.；
3 parts of peppermint extract liquor；
3 parts of Flos Chrysanthemi Indici extract.
Table 1 is influence of the additive amount of rubbing agent to expeling tooth stain ability
It can be obtained by table 1, after having used the rubbing agent of longan seed powder and Herba Euphorbiae Humifusae powder as compounding, drive away tooth stain
Ability enhance, and either can reach 91 for the expeling dirt ability of the tooth stain that has been aged 15 days or 30 days
More than, and the compounding proportioning that optimal expeling soils are the longan seed powder and Herba Euphorbiae Humifusae powder used is 2:1.
In order to test the effect of the present embodiment 1-1 to embodiment 1-3 obtains the hemostasis aspect of oral cavity nursing agent, mouse is carried out
Clinical hemostasis experiment mice clinical hemostasis experiment.
Clinical trial of stopping blooding uses blank lotion, Colgate-Palmolive toothpaste, Crest toothpaste, embodiment 1-1 into embodiment 1-3
Oral cavity nursing agent as examination object sample.
It is carried out using hemostasis observation method is damaged to mouse liver local woanded surface.Take the kunming mice 108 of health, weight
18~22g, male and female dual-purpose.After anesthetized mice, liver is cut in left lobe of liver with operating scissors and be about 0.5cm, wide about 0.5cm, it is high about
0.5cm after the blood for wiping ejection, immediately in situation portion spreading object sample 0.5g to be tried, oppresses 1min, after 1min with 200g counterweights
Counterweight is removed, haemostatic effect is observed, until not bleeding.Such as still bleeding, add to apply and pressurize after object sample is tried, observed every 30s
Once, bleeding stopping period is recorded, is such as no more than 3min, being then denoted as can stop blooding；Such as fail to stop blooding more than 3min, be then denoted as and fail to stop
Blood, experimental result are shown in Table 2.
The clinical blood coagulation hemostasis experimental result of 2 mouse of table
| Try object sample | Experiment number | Bleeding stopping period |
| Blank lotion | 18 | ＞ 3 |
| Colgate-Palmolive toothpaste | 18 | 2.65±0.22 |
| Crest toothpaste | 18 | 2.51±0.18 |
| The oral cavity nursing agent of embodiment 1-1 | 18 | 2.17±0.15 |
| The oral cavity nursing agent of embodiment 1-2 | 18 | 2.11±0.13 |
| The oral cavity nursing agent of embodiment 1-3 | 18 | 2.06±0.12 |
As shown in Table 2, the oral cavity nursing agent of embodiment 1-1 to embodiment 1-3 is to mouse liver local woanded surface bleeding due to trauma
There is apparent blood coagulation haemostatic effect.
Embodiment 2
A kind of antianaphylactic hemostasis oral cavity nursing agent includes following components in parts by weight：
1.2 parts of Irish moss；
3.5 parts of Cocoamidopropyl betaine；
3.0 parts of lauryl sodium sulfate；
30 parts of butanediol；
0.3 part of saccharin sodium；
0.7 part of hydroxyethyl cellulose；
17 parts of longan seed powder, 8 parts of Herba Euphorbiae Humifusae powder；
0.06 part of potassium sorbate；
20 parts of deionized water；
Yellow 5 parts of Honegsukle flower P.E；
8 parts of Lotus Plumule P.E.；
6 parts of peppermint extract liquor；
5 parts of Flos Chrysanthemi Indici extract.
The oral cavity nursing agent of the present embodiment is 97/8 day for the expeling ability of the tooth stain of ageing 15 days；
Expeling ability for the ageing tooth stain of 30 days is 91/12 day.
Embodiment 3
A kind of antianaphylactic hemostasis oral cavity nursing agent includes following components in parts by weight：
1 part of Irish moss；
2.5 parts of Cocoamidopropyl betaine；
2.0 parts of lauryl sodium sulfate；
32 parts of propylene glycol；
0.5 part of xylitol；
0.6 part of carbomer；
13.5 parts of longan seed powder, Herba Euphorbiae Humifusae powder 11.5；
0.04 part of isothiazolinone；
15 parts of deionized water；
8 parts of Honegsukle flower P.E；
12 parts of Lotus Plumule P.E.；
8 parts of peppermint extract liquor；
6 parts of Flos Chrysanthemi Indici extract；
The oral cavity nursing agent of the present embodiment is 97/8 day for the expeling ability of the tooth stain of ageing 15 days；
Expeling ability for the ageing tooth stain of 30 days is 92/11 day.
Embodiment 4
A kind of antianaphylactic hemostasis oral cavity nursing agent includes following components in parts by weight：
1.75 parts of Irish moss；
2.6 parts of Cocoamidopropyl betaine；
1.5 parts of lauryl sodium sulfate；
35 parts of glycine betaine；
0.3 part of saccharin sodium；
0.2 part of sodium carboxymethylcellulose, 0.2 part of hydroxyethyl cellulose, 0.3 part of carbomer；
8 parts of longan seed powder 11, Herba Euphorbiae Humifusae powder；
Paraben esters 0.25,0.15 part of potassium sorbate；
22 parts of deionized water.
7 parts of Honegsukle flower P.E；
11 parts of Lotus Plumule P.E.；
5 parts of peppermint extract liquor；
7 parts of Flos Chrysanthemi Indici extract.
The oral cavity nursing agent of the present embodiment is 96/8 day for the expeling ability of the tooth stain of ageing 15 days；
Expeling ability for the ageing tooth stain of 30 days is 92/19 day.
Embodiment 5
A kind of antianaphylactic hemostasis oral cavity nursing agent includes following components in parts by weight：
1.6 parts of Irish moss；
3.2 parts of Cocoamidopropyl betaine；
2.5 parts of lauryl sodium sulfate；
30 parts of butanediol；
0.4 part of xylitol；
0.4 part of sodium carboxymethylcellulose, 0.2 part of hydroxyethyl cellulose；
9 parts of longan seed powder, 7 parts of Herba Euphorbiae Humifusae powder；
0.02 part of isothiazolinone, 0.03 part of paraben esters；
14 parts of deionized water；
6 parts of Honegsukle flower P.E；
10 parts of Lotus Plumule P.E.；
4 parts of peppermint extract liquor；
4 parts of Flos Chrysanthemi Indici extract.
The oral cavity nursing agent of the present embodiment is 96/9 day for the expeling ability of the tooth stain of ageing 15 days；
Expeling ability for the ageing tooth stain of 30 days is 91/18 day.
Embodiment 6
A kind of antianaphylactic hemostasis oral cavity nursing agent includes following components in parts by weight：
1.5 parts of Irish moss；
2.8 parts of Cocoamidopropyl betaine；
2 parts of lauryl sodium sulfate；
38 parts of propylene glycol；
0.3 part of xylitol, 0.2 part of saccharin sodium；
0.1 part of sodium carboxymethylcellulose, 0.3 part of carbomer；
10 parts of longan seed powder, 11.5 parts of Herba Euphorbiae Humifusae powder；
0.05 part of isothiazolinone；
17.5 parts of deionized water；
7.5 parts of Honegsukle flower P.E；
9 parts of Lotus Plumule P.E.；
6.5 parts of peppermint extract liquor；
5.5 parts of Flos Chrysanthemi Indici extract.
The oral cavity nursing agent of the present embodiment is 97/9 day for the expeling ability of the tooth stain of ageing 15 days；For ageing
The expeling ability of the tooth stain of 30 days is 91/13 day.
Embodiment 7
A kind of antianaphylactic hemostasis oral cavity nursing agent includes following components in parts by weight：
2 parts of Irish moss；
3.2 parts of Cocoamidopropyl betaine；
2.7 parts of lauryl sodium sulfate；
10 parts of propylene glycol, 21 parts of glycine betaine；
0.3 part of saccharin sodium；
0.25 part of hydroxyethyl cellulose, 0.35 part of carbomer；
11 parts of longan seed powder, 11 parts of Herba Euphorbiae Humifusae powder；
0.01 part of isothiazolinone, 0.01 part of potassium sorbate；
14.5 parts of deionized water；
6.5 parts of Honegsukle flower P.E；
8.5 parts of Lotus Plumule P.E.；
3.5 parts of peppermint extract liquor；
4.5 parts of Flos Chrysanthemi Indici extract.
The oral cavity nursing agent of the present embodiment is 97/7 day for the expeling ability of the tooth stain of ageing 15 days；For ageing
The expeling ability of the tooth stain of 30 days is 92/12 day.
Embodiment 8
A kind of antianaphylactic hemostasis oral cavity nursing agent includes following components in parts by weight：
1.8 parts of Irish moss；
2.1 parts of Cocoamidopropyl betaine；
2.5 parts of lauryl sodium sulfate；
24 parts of butanediol, 10 parts of glycine betaine；
0.3 part of xylitol, 0.1 part of saccharin sodium；
0.55 part of hydroxyethyl cellulose；
9 parts of longan seed powder, 15 parts of Herba Euphorbiae Humifusae powder；
0.01 part of isothiazolinone, 0.02 part of paraben esters；
20.5 parts of deionized water；
7 parts of Honegsukle flower P.E；
10.5 parts of Lotus Plumule P.E.；
7.5 parts of peppermint extract liquor；
6 parts of Flos Chrysanthemi Indici extract.
The oral cavity nursing agent of the present embodiment is 97/10 day for the expeling ability of the tooth stain of ageing 15 days；For old
The expeling ability for changing the tooth stain of 30 days is 91/17 day.
Embodiment 9
A kind of antianaphylactic hemostasis oral cavity nursing agent includes following components in parts by weight：
0.9 part of Irish moss；
2.7 parts of Cocoamidopropyl betaine；
1.0 parts of lauryl sodium sulfate；
28 parts of propylene glycol, butanediol or glycine betaine；
0.25 part of xylitol；
0.35 part of sodium carboxymethylcellulose；
8 parts of longan seed powder, 10 parts of Herba Euphorbiae Humifusae powder；
0.02 part of isothiazolinone, 0.01 part of paraben esters, 0.03 part of potassium sorbate；
15 parts of deionized water；
4 parts of Honegsukle flower P.E；
8 parts of Lotus Plumule P.E.；
6 parts of peppermint extract liquor；
5 parts of Flos Chrysanthemi Indici extract.
The oral cavity nursing agent of the present embodiment is 97/9 day for the expeling ability of the tooth stain of ageing 15 days；For ageing
The expeling ability of the tooth stain of 30 days is 91/15 day.
Embodiment 10
A kind of antianaphylactic hemostasis oral cavity nursing agent includes following components in parts by weight：
0.8 part of Irish moss；
3.3 parts of Cocoamidopropyl betaine；
1.8 parts of lauryl sodium sulfate；
14 parts of propylene glycol, 23 parts of butanediol；
0.2 part of xylitol, 0.25 part of saccharin sodium；
0.5 part of carbomer；
12 parts of longan seed powder, 8 parts of Herba Euphorbiae Humifusae powder；
0.01 part of potassium sorbate, 0.02 part of isothiazolinone；
25 parts of deionized water；
8 parts of Honegsukle flower P.E；
12 parts of Lotus Plumule P.E.；
7 parts of peppermint extract liquor；
6 parts of Flos Chrysanthemi Indici extract.
The oral cavity nursing agent of the present embodiment is 98/8 day for the expeling ability of the tooth stain of ageing 15 days；For ageing
The expeling ability of the tooth stain of 30 days is 92/12 day.
The technical principle of the present invention is described above in association with specific embodiment.These descriptions are intended merely to explain the present invention's
Principle, and limiting the scope of the invention cannot be construed in any way.Based on explanation herein, the technology of this field
Personnel would not require any inventive effort the other specific embodiments that can associate the present invention, these modes are fallen within
Within protection scope of the present invention.
Claims (7)
1. a kind of antianaphylactic hemostasis oral cavity nursing agent, which is characterized in that it includes following components in parts by weight：
0.5~2 part of Irish moss；
1.5~3.5 parts of Cocoamidopropyl betaine；
1.0~3.0 parts of lauryl sodium sulfate；
28~40 parts of moisturizer；
0.2~0.5 part of sweetener；
0.3~0.7 part of thickener；
30~50 parts of rubbing agent；
10~25 parts of deionized water；
4~8 parts of Honegsukle flower P.E；
7~12 parts of Lotus Plumule P.E.；
3~8 parts of peppermint extract liquor；
3~7 parts of Flos Chrysanthemi Indici extract；
The rubbing agent is longan seed powder and the compounding of Herba Euphorbiae Humifusae powder.
2. a kind of antianaphylactic hemostasis oral cavity nursing agent according to claim 1, it is characterised in that：It further includes 0.02-
0.06 portion of preservative.
3. a kind of antianaphylactic hemostasis oral cavity nursing agent according to claim 2, it is characterised in that：The preservative is different
Mixture more than one or both of thiazolinone, paraben esters, potassium sorbate.
4. a kind of antianaphylactic hemostasis oral cavity nursing agent according to claim 1, it is characterised in that：The moisturizer is third
The one or more of which compounding of glycol, butanediol or glycine betaine.
5. a kind of antianaphylactic hemostasis oral cavity nursing agent according to claim 1, it is characterised in that：The sweetener is sugar
The one or two of smart sodium or xylitol.
6. a kind of antianaphylactic hemostasis oral cavity nursing agent according to claim 1, it is characterised in that：The thickener is carboxylic
Sodium carboxymethylcellulose pyce, hydroxyethyl cellulose, one or more compoundings of carbomer.
7. a kind of antianaphylactic hemostasis oral cavity nursing agent according to claim 1, it is characterised in that：The longan seed powder
End, the size of Herba Euphorbiae Humifusae powder are 500-1000 mesh.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711434849.XA CN108042424A (en) | 2017-12-26 | 2017-12-26 | A kind of antianaphylactic hemostasis oral cavity nursing agent |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201711434849.XA CN108042424A (en) | 2017-12-26 | 2017-12-26 | A kind of antianaphylactic hemostasis oral cavity nursing agent |
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| CN108042424A true CN108042424A (en) | 2018-05-18 |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104248571A (en) * | 2014-09-19 | 2014-12-31 | 云南七丹药业股份有限公司 | Purely natural plant-containing abradant toothpaste and preparation method thereof |
| CN105193674A (en) * | 2015-10-30 | 2015-12-30 | 成都顺发消洗科技有限公司 | Antiallergic toothpaste |
-
2017
- 2017-12-26 CN CN201711434849.XA patent/CN108042424A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104248571A (en) * | 2014-09-19 | 2014-12-31 | 云南七丹药业股份有限公司 | Purely natural plant-containing abradant toothpaste and preparation method thereof |
| CN105193674A (en) * | 2015-10-30 | 2015-12-30 | 成都顺发消洗科技有限公司 | Antiallergic toothpaste |
Non-Patent Citations (2)
| Title |
|---|
| 熊辅信，等: "《中药现代研究荟萃》", 31 May 2002, 云南科技出版社 * |
| 老中医养生堂: "《本草纲目中药草使用图鉴》", 30 April 2016, 福建科学技术出版社 * |
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Application publication date: 20180518 |