CN107961210A - A kind of whitening spot-removing skin care item containing sealwort stem cell extract - Google Patents
A kind of whitening spot-removing skin care item containing sealwort stem cell extract Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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Abstract
The invention discloses a kind of whitening spot-eliminating composition, the composition contains the component of following parts by weight：1.1~9.7 parts of 0.028~3.4 part of sealwort stem cell extract, 0.7~7.3 part of bermuda lily extract, 0.81~8.5 part of Katsumadai seed extract, 0.69~8.2 part of monkey-bread tree extract and caraway extract.Meanwhile the invention also discloses the skin care item containing above-mentioned composition.The skin care item of the present invention contain sealwort stem cell extract, bermuda lily extract, Katsumadai seed extract, monkey-bread tree extract and caraway extract, have the effect of good whitening and nti-freckle；In addition, the skin care item of the present invention are free of preservative, it is nontoxic to skin safe.
Description
Technical field
The present invention relates to technical field of skin care, especially a kind of whitening spot-removing skin care containing sealwort stem cell extract
Product.
Background technology
The skin of the mankind is usually exposed under air and sunlight, can be influenced be subject to many external and internal factor.It is external
Factor (contains various people including ultraviolet radiation, environmental pollution, wind, heat, infrared radiation, low humidity, low-quality cosmetics
Work chemical reagent) etc.；And internal factor includes the biochemical change in actual age and skin.Either external factor is still
Internal factor, these factors cause to produce obvious skin injury sign, such as microgroove, fold, melanin pigmentation mistake occur
Degree, sallow, sagging, livid ring around eye, swollen eye etc..
In addition, facial colour spot, hospital is also referred to as face's color spot, refers to face's spot different with ambient color.Facial colour spot
Crack cause it is very much, species is more complicated, and facial colour spot is due to the increase of dermal melanin and a kind of common face for being formed
Portion is brown or melanin pigmentation, the skin disease for damaging capacitive, is mainly in cheek and forehead position, solarization postemphasis.It is common
In women, with gestation, the paramenia of Long-term Oral contraceptive is related, belongs to black pigment used by women in ancient times to paint their eyebrows blackspot, the chloasma hepaticum of the traditional Chinese medical science.
The four big reasons that face's color spot is formed are as follows：
(1) genetic cause.Autosomal inheritance is face's color spot main reason.More since 5 years old or so children, Nv Xingju
More, spring and summer weight, the autumn and winter are light.The filbert spot to yellowish-brown needle point to grain of rice size, is symmetrically distributed in face (particularly nose
Portion)；
(2) ultraviolet irradiates.Ultraviolet irradiation in daylight is the major reason that face's color spot is formed, this is also to need summer
Where wanting the reason for sun-proof.When skin receives excessive solar radiation, epidermis will produce more melanin granules, and the latter can be with
Ultraviolet is absorbed, protection human body escapes injury.Skin meeting blackening is exactly this reason after everybody gets sun.Moreover, ultraviolet
Irradiation can cause chloasma, common face's color spot color burn；
(3) endocrine reason.Endocrine disorder is also the major reason that women produces face's color spot, menstrual period and gestation
The change of the internal sex hormone level of phase, can influence the generation of melanin.In addition, usually cause mood when endocrine is unstable
It is unstable, also face's color spot can be caused to be formed indirectly；
(4) habits and customs problem.The bad life habits such as pressure, partial eclipse, sleep insufficiency can also make melanin increase, sleep
Time unstable people, the metabolic rate of skin is also bad, can influence the generation of melanin granule.
On October 25th, 2010, Nature Biotechnology have delivered the research institute of the Unhwa Corp companies of South Korea
It is successfully separated first and has cultivated the paper of plant stem cell, and certification has been obtained to the identity of plant stem cell, plant does
The research of cell enters the stage of high speed development.
In simple terms, there are two " group " cells for being located at plant tip in plant, they have powerful self-renewing
Ability, can not only be divided into autogenous cell, moreover it is possible to and any other plant cell is divided into, is qualified " general-purpose cell ",
Moreover, they, which also have, continues splitting ability so that many large-scale plant existences more than thousand.
2012, " plant stem cell " technology was studied in the effect of beauty and health care field and has been achieved for certain progress,
Prove metabolism of the plant stem cell to raising skin, improve microcirculation, tightening and recovery skin elasticity have major application
Value.
The content of the invention
Based on this, provide one kind it is an object of the invention to overcome in place of above-mentioned the deficiencies in the prior art and can have concurrently and dispel
The skin care item of spot and whitening effect, the skin care item are safe and non-toxic to skin, will not cause skin allergy.
To achieve the above object, this invention takes following technical scheme：
As the first aspect of the invention, the present invention provides a kind of whitening spot-eliminating composition, the composition contains
The component of following parts by weight：0.028~3.4 part of sealwort stem cell extract, 0.7~7.3 part of bermuda lily extract, in one's early teens
1.1~9.7 parts of 0.81~8.5 part of extract, 0.69~8.2 part of monkey-bread tree extract and caraway extract.
Wherein, sealwort stem cell can play interference effect by epigenetic factor pair human skin cell, can be effective
The power of regeneration of skin progenitor cell is encouraged, hyperplasia fibrillar structure albumen, accelerates self more raw and reparation of skin；In addition, sealwort has
There are boosting qi and nourishing yin, invigorating the spleen, moistening lung, the effect of kidney-nourishing；Lily is removed containing protein 21.29%, fat 12.43%, reduced sugar
11.47%th, starch 1.61%, and calcium, phosphorus, iron, per hectogram containing nutrition such as 1.443 milligrams of vitamin Bs, 21.2 milligrams of vitamin Cs
It is plain outer, also containing some special nutritional ingredients, a variety of alkaloids of such as colchicin.These component comprehensive functions in human body,
Not only there is the work(of good nutritious tonifying, but also have to a variety of Seasonal diseases caused by dry in autumn certain
Preventive and therapeutic effect；It can be used for internal retention of cold wetness, abdominal fullness and distention crymodynia in one's early teens, belch is vomitted inverse, the disease such as do not feel like eating；Monkey-bread tree whole body
All be medicine, fruit, leaf and bark can be used as medicine, can with anti-inflammatory, bring down a fever, preventing and curing malaria disease, its fruit, leaf and bark can enter
Medicine, has effects that nourishing the stomach cholagogic, clearing heat for detumescence, hemostasis antidiarrheal and tranquilizing and allaying excitement, scientists are decomposited from baobab fruit
A kind of material that can suppress stomach cancer cell and be formed and extended, and thus opened the normal African for eating baobab fruit and hardly suffered from stomach
The slurries of the secret of cancer, its leaf and fruit, or local common anti-inflammation drugs；Caraway scientific name coriander, is used as medicine, have wind dispelling,
Promoting eruption, stomach invigorating, the effect of eliminating the phlegm.
Preferably, the mass ratio of the sealwort stem cell extract, bermuda lily extract and Katsumadai seed extract is
0.07~1.2：2.9：1.8~4.1.It is highly preferred that the sealwort stem cell extract, bermuda lily extract and carry in one's early teens
The mass ratio for taking thing is 0.27：2.9：3.3.Present inventor has found through test of many times, when sealwort stem cell in skin care item
The mass ratio of extract, bermuda lily extract and Katsumadai seed extract is 0.07~1.2：2.9：When 1.8~4.1, skin care item
Whitening effect it is preferable；And when the matter of sealwort stem cell extract, bermuda lily extract and Katsumadai seed extract in skin care item
Amount is than being 0.27：2.9：When 3.3, the whitening effect of skin care item is more preferably.
Preferably, the mass ratio of the sealwort stem cell extract and monkey-bread tree extract is 0.31~2.2：3.9.More
Preferably, the mass ratio of the sealwort stem cell extract and monkey-bread tree extract is 0.47：3.9.Present inventor
Found through test of many times, when the mass ratio of sealwort stem cell extract and monkey-bread tree extract is 0.31~2.2 in skin care item：
When 3.9, the freckle effect of skin care item is preferable；And when the quality of sealwort stem cell extract and monkey-bread tree extract in skin care item
Than for 0.47：When 3.9, the freckle effect of skin care item is more preferably.
Preferably, the composition contains the component of following parts by weight：0.27 part of sealwort stem cell extract, bermuda lily
9.7 parts of 2.9 parts of extract, 3.3 parts of Katsumadai seed extract, 2.24 parts of monkey-bread tree extract and caraway extract.The application's
Inventor has found through test of many times, when containing 0.27 part of sealwort stem cell extract, bermuda lily extract 2.9 in skin care item
When part, 3.3 parts of Katsumadai seed extract, 2.24 parts of monkey-bread tree extract and 9.7 parts of caraway extract, the whitening of skin care item and dispel
Spot effect is all good.
As the second aspect of the invention, present invention also offers a kind of whitening spot-removing skin care item, the skin care item bag
Containing above-mentioned composition.
Preferably, sealwort stem cell extract, bermuda lily extract, Katsumadai seed extract, monkey face in the skin care item
The quality percentage total amount of bag tree extract and caraway extract is 8.3~10.7%.Present inventor sends out through test of many times
It is existing, when sealwort stem cell extract, bermuda lily extract, Katsumadai seed extract, monkey-bread tree extract and perfume (or spice) in skin care item
When the quality percentage total amount of dish extract is 8.3~10.7%, the freckle effect of skin care item is more preferably.
Preferably, the sealwort stem cell extract is prepared by the following：
S1, sealwort new life root or branch sterilization, after removing xylem and marrow, be inoculated in inducing culture, Fiber differentiation
Obtain cambial cell；
S2, the cambial cell access proliferated culture medium, shaking table culture obtains unicellular through squamous subculture；
S3, by it is described it is unicellular be inoculated in proliferated culture medium through expand cultivate, obtain sealwort stem cell；
S4, gained sealwort stem cell obtain the sealwort stem cell extract through the micro-nano method broken wall of low temperature.
Wherein, the micro-nano method broken wall of low temperature refers to make its freezing in a low temperature of sealwort stem cell is placed on -170 DEG C, then
Melt at normal temperatures, so repeatedly so that the cell membrane of sealwort stem cell crushes；This method can by the vital activity of stem cell with
Power of regeneration is assigned in skin care item, is absorbed via skin, can be remarkably promoted nutrition and be penetrated into and absorb, can effectively lift skin actively
Property, improve skin quality from cell aspect, significantly increase the vigor of Skin Cell.
Preferably, the bermuda lily extract is prepared by the following：Bermuda lily bulb is broken through high speed bead mill method
After wall, bermuda lily extract is obtained using water extraction；
The Katsumadai seed extract is prepared by the following：Take in one's early teens leaf after ultrasonication, obtained using alcohol extracting method
To Katsumadai seed extract；
The monkey-bread tree extract is prepared by the following：The trunk of monkey-bread tree is taken to crush, it is then micro- through low temperature
After nanometer method broken wall, monkey-bread tree extract is obtained using alcohol extracting method；
The caraway extract is prepared by the following：Caraway leaf is taken to be carried after the micro-nano method broken wall of low temperature using water
Method obtains caraway extract.Wherein, alcohol extracting method is preferably extracted using ethanol or methanol.
Relative to the prior art, beneficial effects of the present invention are：
The skin care item of the present invention contain sealwort stem cell extract, bermuda lily extract, Katsumadai seed extract, baobab
Extract and caraway extract are set, the effect with good whitening and nti-freckle；In addition, the skin care item of the present invention are free of anti-corrosion
Agent, it is nontoxic to skin safe.
Embodiment
To better illustrate the object, technical solutions and advantages of the present invention, below in conjunction with specific embodiment to the present invention
It is described further.
Embodiment 1
A kind of a kind of embodiment of whitening spot-eliminating composition in the present invention, the composition contain following parts by weight into
Point：0.028 part of sealwort stem cell extract, 7.3 parts of bermuda lily extract, 0.81 part of Katsumadai seed extract, monkey-bread tree carry
Take 1.1 parts of 8.2 parts of thing and caraway extract.
A kind of embodiment of whitening spot-removing skin care item in the present invention, the skin care item include above-mentioned composition, saualane 36
Part, 18 parts of butanediol, 41 parts of Arabic gum and 78 parts of mixing of water, wherein, sealwort stem cell extract, bermuda lily extraction
The percentage that thing, Katsumadai seed extract, the gross mass of monkey-bread tree extract and caraway extract account for skin care quality is
11.2%.
The specific preparation method of above-mentioned whitening spot-removing skin care item includes the following steps：
(1) sealwort stem cell extract is prepared by the following：
S1, the sterilization of sealwort new life root, after removing xylem and marrow, be inoculated in inducing culture, Fiber differentiation obtains shape
Into confluent monolayer cells；
S2, cambial cell access proliferated culture medium, shaking table culture obtains unicellular through squamous subculture；
S3, by it is unicellular be inoculated in proliferated culture medium through expand cultivate, obtain sealwort stem cell；
S4, gained sealwort stem cell obtain the sealwort stem cell extract through the micro-nano method broken wall of low temperature.
(2) bermuda lily extract is prepared by the following：Bermuda lily bulb uses after high speed bead mill method broken wall
Water extraction obtains bermuda lily extract；
Katsumadai seed extract is prepared by the following：Take in one's early teens leaf after ultrasonication, obtained using ethanol extraction method
To Katsumadai seed extract；
Monkey-bread tree extract is prepared by the following：The trunk of monkey-bread tree is taken to crush, it is then micro-nano through low temperature
After method broken wall, monkey-bread tree extract is obtained using methanol extraction；
Caraway extract is prepared by the following：Caraway leaf is taken to be obtained after the micro-nano method broken wall of low temperature using water extraction
To caraway extract.
(3) by bermuda lily extract, Katsumadai seed extract, monkey-bread tree extract and caraway extract and saualane 36
Part, 18 parts of butanediol, 41 parts of Arabic gum and 78 parts of mixing of water, after 36.2 degrees Celsius stir evenly, it is unnecessary to be filtered to remove
Moisture, obtains lotion, then adds sealwort stem cell extract and is uniformly dispersed up to a kind of whitening spot-removing face cream.
Embodiment 2
A kind of a kind of embodiment of whitening spot-eliminating composition in the present invention, the composition contain following parts by weight into
Point：0.1 part of sealwort stem cell extract, 5.5 parts of bermuda lily extract, 1.4 parts of Katsumadai seed extract, monkey-bread tree extract
6.7 parts and 3.2 parts of caraway extract.
A kind of embodiment of whitening spot-removing skin care item in the present invention, the skin care item include above-mentioned composition, saualane 39
Part, 21 parts of butanediol, 42 parts of Arabic gum and 83 parts of mixing of water, wherein, sealwort stem cell extract, bermuda lily extraction
The percentage that thing, Katsumadai seed extract, the gross mass of monkey-bread tree extract and caraway extract account for skin care quality is
10.7%.
The specific preparation method of above-mentioned whitening spot-removing skin care item includes the following steps：
(1) sealwort stem cell extract is prepared by the following：
S1, the sterilization of sealwort new life branch, after removing xylem and marrow, be inoculated in inducing culture, Fiber differentiation obtains shape
Into confluent monolayer cells；
S2, cambial cell access proliferated culture medium, shaking table culture obtains unicellular through squamous subculture；
S3, by it is unicellular be inoculated in proliferated culture medium through expand cultivate, obtain sealwort stem cell；
S4, gained sealwort stem cell obtain the sealwort stem cell extract through the micro-nano method broken wall of low temperature.
(2) bermuda lily extract is prepared by the following：Bermuda lily bulb uses after high speed bead mill method broken wall
Water extraction obtains bermuda lily extract；
Katsumadai seed extract is prepared by the following：Take in one's early teens leaf after ultrasonication, obtained using methanol extraction
To Katsumadai seed extract；
Monkey-bread tree extract is prepared by the following：The trunk of monkey-bread tree is taken to crush, it is then micro-nano through low temperature
After method broken wall, monkey-bread tree extract is obtained using ethanol extraction method；
Caraway extract is prepared by the following：Caraway leaf is taken to be obtained after the micro-nano method broken wall of low temperature using water extraction
To caraway extract.
(3) by bermuda lily extract, Katsumadai seed extract, monkey-bread tree extract and caraway extract and saualane 39
Part, 21 parts of butanediol, 42 parts of Arabic gum and 83 parts of mixing of water, after 36.4 degrees Celsius stir evenly, it is unnecessary to be filtered to remove
Moisture, obtains lotion, then adds sealwort stem cell extract and is uniformly dispersed up to a kind of whitening spot-removing face cream.
Embodiment 3
A kind of a kind of embodiment of whitening spot-eliminating composition in the present invention, the composition contain following parts by weight into
Point：0.27 part of sealwort stem cell extract, 2.9 parts of bermuda lily extract, 3.3 parts of Katsumadai seed extract, monkey-bread tree extraction
9.7 parts of 2.24 parts of thing and caraway extract.
A kind of embodiment of whitening spot-removing skin care item in the present invention, the skin care item include above-mentioned composition, saualane 40
Part, 23 parts of butanediol, 45 parts of Arabic gum and 92 parts of mixing of water, wherein, sealwort stem cell extract, bermuda lily extraction
The percentage that thing, Katsumadai seed extract, the gross mass of monkey-bread tree extract and caraway extract account for skin care quality is
9.6%.
The specific preparation method of above-mentioned whitening spot-removing skin care item includes the following steps：
(1) sealwort stem cell extract is prepared by the following：
S1, the sterilization of sealwort new life root, after removing xylem and marrow, be inoculated in inducing culture, Fiber differentiation obtains shape
Into confluent monolayer cells；
S2, cambial cell access proliferated culture medium, shaking table culture obtains unicellular through squamous subculture；
S3, by it is unicellular be inoculated in proliferated culture medium through expand cultivate, obtain sealwort stem cell；
S4, gained sealwort stem cell obtain the sealwort stem cell extract through the micro-nano method broken wall of low temperature.
(2) bermuda lily extract is prepared by the following：Bermuda lily bulb uses after high speed bead mill method broken wall
Water extraction obtains bermuda lily extract；
Katsumadai seed extract is prepared by the following：Take in one's early teens leaf after ultrasonication, obtained using ethanol extraction method
To Katsumadai seed extract；
Monkey-bread tree extract is prepared by the following：The trunk of monkey-bread tree is taken to crush, it is then micro-nano through low temperature
After method broken wall, monkey-bread tree extract is obtained using ethanol extraction method；
Caraway extract is prepared by the following：Caraway leaf is taken to be obtained after the micro-nano method broken wall of low temperature using water extraction
To caraway extract.
(3) by bermuda lily extract, Katsumadai seed extract, monkey-bread tree extract and caraway extract and saualane 40
Part, 23 parts of butanediol, 45 parts of Arabic gum and 92 parts of mixing of water, after 36.9 degrees Celsius stir evenly, it is unnecessary to be filtered to remove
Moisture, obtains lotion, then adds sealwort stem cell extract and is uniformly dispersed up to a kind of whitening spot-removing face cream.
Embodiment 4
A kind of a kind of embodiment of whitening spot-eliminating composition in the present invention, the composition contain following parts by weight into
Point：1.3 parts of sealwort stem cell extract, 1.1 parts of bermuda lily extract, 5.6 parts of Katsumadai seed extract, monkey-bread tree extract
4.1 parts and 5.4 parts of caraway extract.
A kind of embodiment of whitening spot-removing skin care item in the present invention, the skin care item include above-mentioned composition, saualane 44
Part, 19 parts of butanediol, 47 parts of Arabic gum and 89 parts of mixing of water, wherein, sealwort stem cell extract, bermuda lily extraction
The percentage that thing, Katsumadai seed extract, the gross mass of monkey-bread tree extract and caraway extract account for skin care quality is
8.8%.
The specific preparation method of above-mentioned whitening spot-removing skin care item includes the following steps：
(1) sealwort stem cell extract is prepared by the following：
S1, the sterilization of sealwort new life branch, after removing xylem and marrow, be inoculated in inducing culture, Fiber differentiation obtains shape
Into confluent monolayer cells；
S2, cambial cell access proliferated culture medium, shaking table culture obtains unicellular through squamous subculture；
S3, by it is unicellular be inoculated in proliferated culture medium through expand cultivate, obtain sealwort stem cell；
S4, gained sealwort stem cell obtain the sealwort stem cell extract through the micro-nano method broken wall of low temperature.
(2) bermuda lily extract is prepared by the following：Bermuda lily bulb uses after high speed bead mill method broken wall
Water extraction obtains bermuda lily extract；
Katsumadai seed extract is prepared by the following：Take in one's early teens leaf after ultrasonication, obtained using methanol extraction
To Katsumadai seed extract；
Monkey-bread tree extract is prepared by the following：The trunk of monkey-bread tree is taken to crush, it is then micro-nano through low temperature
After method broken wall, monkey-bread tree extract is obtained using methanol extraction；
Caraway extract is prepared by the following：Caraway leaf is taken to be obtained after the micro-nano method broken wall of low temperature using water extraction
To caraway extract.
(3) by bermuda lily extract, Katsumadai seed extract, monkey-bread tree extract and caraway extract and saualane 44
Part, 19 parts of butanediol, 47 parts of Arabic gum and 89 parts of mixing of water, after 37.5 degrees Celsius stir evenly, it is unnecessary to be filtered to remove
Moisture, obtains lotion, then adds sealwort stem cell extract and is uniformly dispersed up to a kind of whitening spot-removing face cream.
Embodiment 5
A kind of a kind of embodiment of whitening spot-eliminating composition in the present invention, the composition contain following parts by weight into
Point：3.4 parts of sealwort stem cell extract, 0.7 part of bermuda lily extract, 8.5 parts of Katsumadai seed extract, monkey-bread tree extract
0.69 part and 7.8 parts of caraway extract.
A kind of embodiment of whitening spot-removing skin care item in the present invention, the skin care item include above-mentioned composition, saualane 47
Part, 28 parts of butanediol, 55 parts of Arabic gum and 101 parts of mixing of water, wherein, sealwort stem cell extract, bermuda lily extraction
The percentage that thing, Katsumadai seed extract, the gross mass of monkey-bread tree extract and caraway extract account for skin care quality is
8.3%.
The specific preparation method of above-mentioned whitening spot-removing skin care item includes the following steps：
(1) sealwort stem cell extract is prepared by the following：
S1, the sterilization of sealwort new life root, after removing xylem and marrow, be inoculated in inducing culture, Fiber differentiation obtains shape
Into confluent monolayer cells；
S2, cambial cell access proliferated culture medium, shaking table culture obtains unicellular through squamous subculture；
S3, by it is unicellular be inoculated in proliferated culture medium through expand cultivate, obtain sealwort stem cell；
S4, gained sealwort stem cell obtain the sealwort stem cell extract through the micro-nano method broken wall of low temperature.
(2) bermuda lily extract is prepared by the following：Bermuda lily bulb uses after high speed bead mill method broken wall
Water extraction obtains bermuda lily extract；
Katsumadai seed extract is prepared by the following：Take in one's early teens leaf after ultrasonication, obtained using ethanol extraction method
To Katsumadai seed extract；
Monkey-bread tree extract is prepared by the following：The trunk of monkey-bread tree is taken to crush, it is then micro-nano through low temperature
After method broken wall, monkey-bread tree extract is obtained using ethanol extraction method；
Caraway extract is prepared by the following：Caraway leaf is taken to be obtained after the micro-nano method broken wall of low temperature using water extraction
To caraway extract.
(3) by bermuda lily extract, Katsumadai seed extract, monkey-bread tree extract and caraway extract and saualane 47
Part, 28 parts of butanediol, 55 parts of Arabic gum and 101 parts of mixing of water, after 36.6 degrees Celsius stir evenly, it is unnecessary to be filtered to remove
Moisture, obtains lotion, then adds sealwort stem cell extract and is uniformly dispersed up to a kind of whitening spot-removing face cream.
The whitening effect test of the skin care item of the present invention of embodiment 6
Test object：The face cream of embodiment 1~5 and the face cream of control group 1~4, wherein, the skin care of control group 1~4
Frost differs only in sealwort stem cell extract, bermuda lily extract and Katsumadai seed extract with the face cream of embodiment 3
Mass ratio it is different, the content of other components and the preparation method of face cream are same as Example 3 in face cream；Control group 1
The mass ratio of sealwort stem cell extract, bermuda lily extract and Katsumadai seed extract is 0.07 successively in~4 face cream：
2.9：1.8；0.61：2.9：2.5；0.93：2.9：3.7；1.2：2.9：4.1.
Test method：Nine groups of face cream altogether, every group of face cream chooses the women 16 of 35~58 years old respectively, after washing one's face,
Sooner or later each to smear face once, usage time is 80 days, is tested using German CK companies skin elasticity tester MPA580+MX18
(detection wavelength 568nm) successively detection pop one's head in using before face cream and using face cream rear face melanin content, calculates skin
Melanin is averaged slip (take facial 4 points).Test result：It is as shown in table 1 below；
The effect for dispelling melanin of the face cream of the present invention of table 1
Interpretation of result：As shown in Table 1, the reduction skin of the face cream of the face cream of embodiment 3 and control group 1~4 is black
The effect of pigment is preferable, correspondingly, sealwort stem cell extract in the face cream of the face cream of embodiment 3 and control group 1~4,
The mass ratio of bermuda lily extract and Katsumadai seed extract all falls within 0.07~1.2：2.9：In the range of 1.8~4.1；Its
In, reduce that the effect of dermal melanin is best with the face cream of embodiment 3, show that the face cream of embodiment 3 brightens skin
Best results.
The freckle effect test of the skin care item of the present invention of embodiment 7
Test object：The face cream of embodiment 1~5 and the face cream of control group 1~4, wherein, the skin care of control group 1~4
Frost differs only in the mass ratio of sealwort stem cell extract and monkey-bread tree extract not compared with the face cream of embodiment 3
Together, the other compositions of face cream and preparation method are identical with the face cream of embodiment 3；Sealwort is done in the face cream of control group 1~4
The mass ratio of cell extract and monkey-bread tree extract is followed successively by 0.31：3.9；1.1：3.9；1.6：3.9；2.2：3.9；
Test method：Choosing face has the adult female (32~60 years old) 144 of color spot, is randomly divided into 9 groups, every group 16
People, counts the gross area of each group member using the facial colour spot before face cream respectively, and before face cream, face cleaning, the morning and evening first is each
Once, face cream is uniformly applied on facial colour spot, after 150 days, counts total face of the facial colour spot of each group member respectively
Product, calculates the mean percentage of facial colour spot reduction.
Test result：It is as shown in table 2 below；
The freckle effect of the face cream of the present invention of table 2
Interpretation of result：As shown in upper table 2, the freckle effect of the face cream of embodiment 3 and 4 and the face cream of control group 1~4
Preferably；Wherein, using the freckle effect of the face cream of embodiment 3 to be best.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than the present invention is protected
The limitation of scope is protected, although being explained in detail with reference to preferred embodiment to the present invention, those of ordinary skill in the art should
Understand, can be to technical scheme technical scheme is modified or replaced equivalently, without departing from the essence of technical solution of the present invention
And scope.
Claims (10)
1. a kind of whitening spot-eliminating composition, it is characterised in that the composition contains the component of following parts by weight：Sealwort stem cell
0.028~3.4 part of extract, 0.7~7.3 part of bermuda lily extract, 0.81~8.5 part of Katsumadai seed extract, monkey-bread tree
1.1~9.7 parts of 0.69~8.2 part of extract and caraway extract.
2. composition according to claim 1, it is characterised in that the sealwort stem cell extract, bermuda lily extraction
The mass ratio of thing and Katsumadai seed extract is 0.07~1.2：2.9：1.8~4.1.
3. composition according to claim 2, it is characterised in that the sealwort stem cell extract, bermuda lily extraction
The mass ratio of thing and Katsumadai seed extract is 0.27：2.9：3.3.
4. composition according to claim 1, it is characterised in that the sealwort stem cell extract and monkey-bread tree extraction
The mass ratio of thing is 0.31~2.2：3.9.
5. composition according to claim 4, it is characterised in that the sealwort stem cell extract and monkey-bread tree extraction
The mass ratio of thing is 0.47：3.9.
6. composition according to claim 1, it is characterised in that the composition contains the component of following parts by weight：It is yellow
Keen-witted and capable 0.27 part of cell extract, 2.9 parts of bermuda lily extract, 3.3 parts of Katsumadai seed extract, monkey-bread tree extract 2.24
9.7 parts of part and caraway extract.
7. a kind of whitening spot-removing skin care item, it is characterised in that the skin care item include such as claim 1~6 any one of them
Composition.
8. skin care item according to claim 7, it is characterised in that sealwort stem cell extract, white flower in the skin care item
Bulbus Lilii extract, Katsumadai seed extract, the quality percentage total amount of monkey-bread tree extract and caraway extract for 8.3~
10.7%.
9. skin care item according to claim 7, it is characterised in that the sealwort stem cell extract obtains by the following method
：
S1, sealwort new life root or branch sterilization, after removing xylem and marrow, be inoculated in inducing culture, Fiber differentiation obtains
Cambial cell；
S2, the cambial cell access proliferated culture medium, shaking table culture obtains unicellular through squamous subculture；
S3, by it is described it is unicellular be inoculated in proliferated culture medium through expand cultivate, obtain sealwort stem cell；
S4, gained sealwort stem cell obtain the sealwort stem cell extract through the micro-nano method broken wall of low temperature.
10. skin care item according to claim 7, it is characterised in that the bermuda lily extract obtains by the following method
：Bermuda lily bulb obtains bermuda lily extract after high speed bead mill method broken wall using water extraction；
The Katsumadai seed extract is prepared by the following：Take in one's early teens leaf after ultrasonication, grass is obtained using alcohol extracting method
Fructus Amomi Rotundus extract；
The monkey-bread tree extract is prepared by the following：The trunk of monkey-bread tree is taken to crush, it is then micro-nano through low temperature
After method broken wall, monkey-bread tree extract is obtained using alcohol extracting method；
The caraway extract is prepared by the following：Caraway leaf is taken to be obtained after the micro-nano method broken wall of low temperature using water extraction
To caraway extract.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2603634A (en) * | 2020-12-21 | 2022-08-10 | Floweressence Cgh Ltd | Flower essence-containing medicaments |
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| CN104920227A (en) * | 2015-07-15 | 2015-09-23 | 广东融和生态农业有限公司 | Stem cell tissue culture seedling raising technique |
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2017
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| CN104920227A (en) * | 2015-07-15 | 2015-09-23 | 广东融和生态农业有限公司 | Stem cell tissue culture seedling raising technique |
| CN105748343A (en) * | 2016-02-25 | 2016-07-13 | 广州市科玮生物技术有限公司 | Natural plant extract composition and application thereof in cosmetics |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2603634A (en) * | 2020-12-21 | 2022-08-10 | Floweressence Cgh Ltd | Flower essence-containing medicaments |
| GB2603634B (en) * | 2020-12-21 | 2023-11-15 | Floweressence Cgh Ltd | Flower essence-containing medicaments |
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Application publication date: 20180427 |