CN107929654A - 一种治疗肋间神经痛的外用药物及其制备方法 - Google Patents
一种治疗肋间神经痛的外用药物及其制备方法 Download PDFInfo
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Abstract
本发明属于中药制剂领域,目的是根据中医治疗肋间神经痛的认识机理而提供一种治疗肋间神经痛的外用药物,所述药物的各个组分及其质量份比如下:鸡血藤10~20g、桃仁10~20g、川芎5~15g、赤芍6~15g、穿山甲3~15g、防风5~12g、白及5~16g、白芷3~16g、大黄5~35g、当归8~18g、延胡索8~18g、荆芥5~12g、薤白5~12g、丹参5~18g、威灵仙6~10g、栝楼实9~30g、土鳖虫3~12g、地龙5~12g、乌药8~18g、郁金8~18g,本发明提供的药物是一个很好的中药组方。
Description
技术领域
本发明属于中药制剂领域,具体涉及一种治疗肋间神经痛的外用药物,特别是供肋间神经痛患者使用的外用药物及其制备方法的领域。
背景技术
祖国医学认为:肋间神经痛是患者的主观症状。肋间神经由胸脊髓向两侧发出经肋间到胸前壁,支配相应胸椎旁背部和胸壁的肌肉的分支及沿肋间走行的感觉分支。因此肋间神经痛是从胸背部沿肋间向斜向前下至胸腹前壁中线带状区疼痛。
临床表现:
肋间神经痛是指一个或几个肋间部位从背部沿肋间向胸腹前壁放射,呈半环状分布。多为单侧受累,也可以双侧同时受累。咳嗽、深呼吸或打喷嚏往往使疼痛加重。查体可有胸椎棘突,棘突间或椎旁压痛和叩痛,少数患者沿肋间有压痛,受累神经支配区可有感觉异常。其疼痛性质多为刺痛或灼痛,有沿沿肋间神经放射的特点。带状疱疹可见局部病变。
那么,就如何找到一种可有效治疗肋间神经痛的中药组合物,是本领域技术人员亟待要解决的问题。
发明内容
随着我国中医中药学的不断发展,在治疗肋间神经痛上,人们逐渐意识到了中医治疗肋间神经痛的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗肋间神经痛的现状,本发明的目的是在于提供一种治疗肋间神经痛的外用药物,以解决肋间神经痛患者早日恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及质量份比,可有效治疗上述肋间神经痛一证。
为达到上述发明的目的,本发明所采用的技术方案为:提供一种治疗肋间神经痛的外用药物及其制备方法,其特征在于,所述药物的各个组分及质量份比如下所示:
鸡血藤10~20g、桃仁10~20g、川芎5~15g、赤芍6~15g、穿山甲3~15g、防风5~12g、白及5~16g、白芷3~16g、大黄5~35g、当归8~18g、延胡索8~18g、荆芥5~12g、薤白5~12g、丹参5~18g、威灵仙6~10g、栝楼实9~30g、土鳖虫3~12g、地龙5~12g、乌药8~18g、郁金8~18g,辅料:醋酸洗必泰和薄荷脑适量。
一种治疗肋间神经痛的外用药物及其制备方法,其特征在于,所述药物的各个组分及质量份比如下所示:
鸡血藤12~17g、桃仁12~17g、川芎6~13g、赤芍7~13g、穿山甲5~13g、防风6~11g、白及6~14g、白芷5~14g、大黄8~31g、当归9~16g、延胡索10~16g、荆芥6~11g、薤白6~11g、丹参6~16g、威灵仙7~9g、栝楼实10~26g、土鳖虫5~11g、地龙6~11g、乌药9~16g、郁金10~16g,辅料:醋酸洗必泰和薄荷脑适量。
一种治疗肋间神经痛的外用药物及其制备方法,其特征在于,所述药物的各个组分及质量份比如下所示:
鸡血藤15g、桃仁15g、川芎12g、赤芍12g、穿山甲12g、防风10g、白及13g、白芷13g、大黄28g、当归14g、延胡索14g、荆芥10g、薤白10g、丹参14g、威灵仙8g、栝楼实23g、土鳖虫10g、地龙10g、乌药14g、郁金14g,辅料:醋酸洗必泰和薄荷脑适量。
一种治疗肋间神经痛的外用药物及其制备方法,其特征在于,所述方法包括如下步骤制备而成:
A、将上述原料中药拣去杂质、粉尘及干燥后,按照质量份比共研为粉末状(采用超微细机研磨)待用;
B、将研磨好的粉末状物放入专用搅拌机药器内进行混合搅拌,待搅拌均匀后待用;
C、将搅拌均匀的粉末状药物放入搅拌机药器内,加入适量的醋酸洗必泰和薄荷脑拌均,即得膏状成品药物,分装密封即可。
一种治疗肋间神经痛的外用药物及其制备方法,其特征在于,所述使用方法为:将制备好的膏状成品药物涂抹在患病处,同时按摩吸收6~12分钟,以皮肤有热感为度。7天为一个疗程,治疗2~4个疗程后,症状消失,病获痊愈。
本发明组方中的各原料中药在中国药典、中国医学大辞典,以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
鸡血藤,性味:味苦、微甘、性温,具有活血舒筋、养血调经之功效,用于治疗手足麻木、肢体瘫痪、风湿痹痛、妇女有经不调、痛经、闭经等症;
桃仁,性味:苦甘、平,无毒,具有破血行瘀、润燥滑肠之功效,用于治疗经闭、癥瘕、热病蓄血、风痹、疟疾、跌打损伤、瘀血肿痛、血燥便秘;
川芎,性味:味辛、性温,具有活血祛瘀、行气开郁、祛风止痛之功效,用于治疗月经不调、经闭痛经、产后瘀滞腥痛、症瘕肿块、胸胁疼痛、头痛眩晕、风寒湿痹、跌打损伤、痈疽疮疡;
赤芍,性味:苦、微寒,具有清热凉血、活血祛瘀之功效,用于治疗温毒发斑、吐血衄血、肠风下血、目赤肿痛、痈肿疮疡、闭经、痛经、崩带淋浊、瘀滞胁痛、疝瘕积聚、跌扑损伤;
穿山甲,性味:味咸、性微寒,具有活血散结、通经下乳、消痈溃坚之功效,用于治疗治血瘀经闭、癥瘕、风湿痹痛、乳汁不下、痈肿、瘰疬等症;
防风,性味:辛、甘、温,具有解表祛风、胜湿、止痉之功效,用于治疗感冒头痛、风湿痹痛、风疹瘙痒、破伤风;
白及,性味:苦甘、凉,具有补肺、止血、消肿、生肌、敛疮之功效,用于治疗肺伤咳血、衄血、金疮出血、痈疽肿毒、溃疡疼痛、汤火灼伤、手足皲裂;
白芷,性味:味辛、性温,具有祛风除湿、通窃止痛、消肿排脓之功效,用于治疗感冒头痛、眉棱骨痛、牙痛、鼻塞、鼻渊、湿胜久泻、妇女白带、痈疽疮疡、毒蛇咬伤;
大黄,性味:苦、寒,具有泻实热、破积滞、行瘀血之功效,用于治疗实热便秘、食积停滞、腹痛、急性阑尾炎、急性传染性肝炎、血瘀经闭、牙痛、衄血、急性结膜炎,外用治烧烫伤、化脓性皮肤病、痈肿疮疡;
当归,性味:性温、味甘辛,具有补血和血、调经止痛、润燥滑肠之功效,用于治疗血虚、面色萎黄、眩晕心悸、血虚、或兼有瘀滞的月经不调、经闭、痛经、虚寒性腹痛、冠心病心绞痛、风湿痹痛、跌打损伤;
延胡索,性味:辛、苦、温,无毒,具有活血、散瘀、理气、止痛之功效,用于治疗心腹腰膝诸痛、月经不调、症瘕、崩中、产后血晕、恶露不尽、跌打损伤;
荆芥,性味:辛、微温,具有解表散风,透疹之功效,用于治疗感冒、头痛、麻疹、风疹、疮疡初起,炒炭治便血、崩漏、产后血晕等症;
薤白,性味:辛、苦、温,具有通阳散结、行气导滞之功效,用于治疗胸痹心痛、脘腹痞满胀痛、泻痢后重;
丹参,性味:味苦、性微寒,具有活血祛瘀、调经止痛、养血安神、凉血消痈之功效,用于治疗妇女月经不调、痛经、经闭、产后瘀滞腹痛、心腹疼痛、癥瘕积聚、热痹肿痛、跌打损伤、热入营血、烦躁不安、心烦失眠、痈疮肿毒;
威灵仙,性味:味辛、咸、微苦、性温,小毒,具有祛风除湿、通络止痛之功效,用于治疗风湿痹痛、肢体麻木、筋脉拘挛、屈伸不利、脚气肿痛、疟疾、骨哽咽喉、并治痰饮积聚;
栝楼实,性味:味甘、微苦、性寒,具有清热化痰、宽胸散结、润燥滑肠之功效,用于治疗肺热咳嗽、胸痹、结胸、消渴、便秘、痈肿疮毒;
土鳖虫,性味:味咸、性寒,具有破血逐瘀、续筋接骨之功效,用于治疗跌打损伤、筋伤骨折、血瘀经闭、产后瘀阻腹痛、瘾瘕痞块等病症;
地龙,性味:味咸、性寒,具有清势止痉、平肝熄风、通经活络、平喘利尿之功效,用于治疗热病发热狂燥、惊痫抽搐、肝阳头痛、中风偏瘫、风湿痹痛、肺热喘咳、小便不通等症;
乌药,性味:辛,温,具有顺气、开郁、散寒、止痛之功效,用于治疗气逆胸腹胀痛、宿食不消、反胃吐食、寒疝、脚气、小便频数等症;
郁金,性味:辛苦、凉,具有行气解郁、凉血破瘀之功效,用于治疗胸腹胁肋诸痛、失心癫狂、热病神昏、吐血、衄血、尿血、血淋、妇女倒经、黄疸等症;
本发明药物是基于中医治疗肋间神经痛的原则,从依据肋间神经痛的病理机制及药理作用认为:就肋间神经痛,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的效果。
具体实施方式
本发明就是针对上述肋间神经痛的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个很好的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种治疗肋间神经痛的外用药物,其特征在于,所述药物的各个组分及质量份比如下所示:
鸡血藤15g、桃仁15g、川芎12g、赤芍12g、穿山甲12g、防风10g、白及13g、白芷13g、大黄28g、当归14g、延胡索14g、荆芥10g、薤白10g、丹参14g、威灵仙8g、栝楼实23g、土鳖虫10g、地龙10g、乌药14g、郁金14g,辅料:醋酸洗必泰和薄荷脑适量。
实施例2:
一种治疗肋间神经痛的外用药物,其特征在于,所述药物的各个组分及质量份比如下所示:
鸡血藤17g、桃仁17g、川芎13g、赤芍13g、穿山甲13g、防风11g、白及14g、白芷14g、大黄31g、当归16g、延胡索16g、荆芥11g、薤白11g、丹参16g、威灵仙9g、栝楼实26g、土鳖虫11g、地龙11g、乌药16g、郁金16g,辅料:醋酸洗必泰和薄荷脑适量。
实施例3:
一种治疗肋间神经痛的外用药物,其特征在于,所述药物的各个组分及质量份比如下所示:
鸡血藤17g、桃仁17g、川芎13g、赤芍13g、穿山甲13g、防风11g、白及14g、白芷14g、大黄31g、当归16g、延胡索16g、荆芥11g、薤白11g、丹参16g、威灵仙9g、栝楼实26g、土鳖虫11g、地龙11g、乌药16g、郁金16g,辅料:醋酸洗必泰和薄荷脑适量。
典型病例
经临床诊断治疗肋间神经痛患者共1170例,年龄为60岁以上的720例,只有470例为60岁以下。1170例患者中痊愈的829例,有效的450例,无效的59例。总有效率达95%。
Claims (3)
1.一种治疗肋间神经痛的外用药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
鸡血藤10~20g、桃仁10~20g、川芎5~15g、赤芍6~15g、穿山甲3~15g、防风5~12g、白及5~16g、白芷3~16g、大黄5~35g、当归8~18g、延胡索8~18g、荆芥5~12g、薤白5~12g、丹参5~18g、威灵仙6~10g、栝楼实9~30g、土鳖虫3~12g、地龙5~12g、乌药8~18g、郁金8~18g,辅料:醋酸洗必泰和薄荷脑适量。
2.根据权利要求1所述的治疗肋间神经痛的外用药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
鸡血藤12~17g、桃仁12~17g、川芎6~13g、赤芍7~13g、穿山甲5~13g、防风6~11g、白及6~14g、白芷5~14g、大黄8~31g、当归9~16g、延胡索10~16g、荆芥6~11g、薤白6~11g、丹参6~16g、威灵仙7~9g、栝楼实10~26g、土鳖虫5~11g、地龙6~11g、乌药9~16g、郁金10~16g,辅料:醋酸洗必泰和薄荷脑适量。
3.根据权利要求1至2所述的治疗肋间神经痛的外用药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
鸡血藤15g、桃仁15g、川芎12g、赤芍12g、穿山甲12g、防风10g、白及13g、白芷13g、大黄28g、当归14g、延胡索14g、荆芥10g、薤白10g、丹参14g、威灵仙8g、栝楼实23g、土鳖虫10g、地龙10g、乌药14g、郁金14g,辅料:醋酸洗必泰和薄荷脑适量。
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