CN107929562A - A kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic - Google Patents

A kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic Download PDF

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CN107929562A
CN107929562A CN201711281025.3A CN201711281025A CN107929562A CN 107929562 A CN107929562 A CN 107929562A CN 201711281025 A CN201711281025 A CN 201711281025A CN 107929562 A CN107929562 A CN 107929562A
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parts
pharmaceutical composition
antipyretic
antalgic
chinese
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李艳阳
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    • A—HUMAN NECESSITIES
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Abstract

The invention discloses a kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic, include the raw material of following parts by weight：38 parts of radix bupleuri, 16 parts of rhizoma Gastrodiae, 0.2 0.8 parts of Chinese ephedra, 3 10 parts of levisticum, 2 12 parts of Chinese cassia tree, 49 parts of grass of meadow rue, 1 10 parts of radix glycyrrhizae, 6 14 parts of river Chinese herbaceous peony, 5 10 parts of honeysuckle, 49 parts of peppermint, 0.5 3 parts windproof, 0.1 1 parts of notopterygium root, 5 15 parts of chrysanthemum, 17 parts of Fructus Forsythiae.Pharmaceutical composition produced by the present invention is non-toxic, and curative effect is fast, is very suitable for Pediatric Clinic application, and convenient to take, and indication scope is wide, and side effect is almost without drug safety degree is high, and medicine source is sufficient, meets growing Pediatric Clinic needs and the market demand.

Description

A kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic
Technical field
The present invention relates to paediatrics field of medical technology, more particularly to a kind of drug regimen for pediatric hospital antipyretic-antalgic Thing.
Background technology
Fever is a kind of symptom more common during paediatrics is gone to a doctor, if temperature is excessive to seriously affect child health even Threaten life, it is therefore desirable to take effective measures reply.The currently used mode of bringing down a fever of bringing down a fever is to give child administration Ah Si Woods takes Merrill Lynch, and in both, the first can stimulate the enteron aisle and liver, kidney of children's fragility.And long-term use of Merrill Lynch, Side effect to kidney is larger, and we have proposed a kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic for this.
The content of the invention
Based on technical problem existing for background technology, the present invention proposes a kind of medicine for pediatric hospital antipyretic-antalgic Composition.
A kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic proposed by the present invention, includes the original of following parts by weight Material：3-8 parts of radix bupleuri, 1-6 parts of rhizoma Gastrodiae, 0.2-0.8 parts of Chinese ephedra, 3-10 parts of levisticum, 2-12 parts of Chinese cassia tree, 4-9 parts of grass of meadow rue, radix glycyrrhizae 1- 10 parts, Chinese herbaceous peony 6-14 parts of river, 5-10 parts of honeysuckle, 4-9 parts of peppermint, 0.5-3 parts windproof, 0.1-1 parts of notopterygium root, 5-15 parts of chrysanthemum, even Stick up 1-7 parts.
Preferably, the raw material of following parts by weight is included：4-7 parts of radix bupleuri, 2-5 parts of rhizoma Gastrodiae, 0.3-0.7 parts of Chinese ephedra, levisticum 5-8 Part, 4-10 parts of Chinese cassia tree, 5-8 parts of grass of meadow rue, 3-8 parts of radix glycyrrhizae, Chinese herbaceous peony 8-12 parts of river, 7-8 parts of honeysuckle, 5-8 parts of peppermint, windproof 1-2 Part, 0.4-0.6 parts of notopterygium root, 7-13 parts of chrysanthemum, 3-5 parts of Fructus Forsythiae.
Preferably, the raw material of following parts by weight is included：6 parts of radix bupleuri, 3 parts of rhizoma Gastrodiae, 0.5 part of Chinese ephedra, 7 parts of levisticum, Chinese cassia tree 7 Part, 7 parts of grass of meadow rue, 6 parts of radix glycyrrhizae, 10 parts of river Chinese herbaceous peony, 7.5 parts of honeysuckle, 6 parts of peppermint, 1.5 parts windproof, 0.5 part of notopterygium root, chrysanthemum 10 Part, 4 parts of Fructus Forsythiae.
Preferably, the radix bupleuri, rhizoma Gastrodiae, the weight ratio of Chinese ephedra are 4-7：2-5：0.3-0.7.
Preferably, the levisticum, Chinese cassia tree, the weight ratio of grass of meadow rue are 5-8：4-10：5-8.
Preferably, the radix glycyrrhizae, river Chinese herbaceous peony, the weight ratio of honeysuckle are 3-8：8-12：7-8.
Preferably, the preparation method of described pharmaceutical composition comprises the following steps：
S1, weighs radix bupleuri, rhizoma Gastrodiae, Chinese ephedra, levisticum, Chinese cassia tree, grass of meadow rue according to deal proportioning, above-mentioned raw materials is cleaned after drying in the shade, It is sequentially placed into mill and is fully ground, obtains mixed powder A；
S2, mixed powder A is put into cooker, is put into the 7-11 times of water measured, and first big fire decocts 0.5-1h, then small fire decocts 1- 2h, filter residue, obtains liquor B；
S3, weighs radix glycyrrhizae, river Chinese herbaceous peony, honeysuckle, peppermint, windproof, notopterygium root, chrysanthemum, Fructus Forsythiae according to deal proportioning, above-mentioned raw materials is washed Only it, dry, pulverize to 120-140 mesh, mix and be put into Decocting pot, be put into the 6-8 times of water measured, big fire decocts 1-3h Afterwards, liquor B is put into Decocting pot, decocts 1-2h with small fire, filter residue, obtains liquor C；
S4, will be filling after liquor C high-temperature sterilization, you can obtain a kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic.
Preferably, in the S2, mixed powder A is put into cooker, is put into the water of 9 times of amounts, first big fire decocts 0.75h, Small fire decocts 1.5h again, and filter residue, obtains liquor B.
In the present invention, radix bupleuri takes off for cold, fever, fevers and chills alternate, malaria, stagnation of QI due to depression of the liver, sternal rib pain, rectal prolapse, uterus Hang down, irregular menstruation；Rhizoma Gastrodiae rhizome be used as medicine to treat have a dizzy spell, the disease such as extremity numbness, child convulsion；Chinese ephedra is warm-natured, acrid flavour, Slight bitter, have sweating cold dispelling, freeing lung and relieving asthma, inducing diuresis for removing edema the effect of；Levisticum is used for wind-cold-dampness arthralgia, to wash pain, few cloudy volt public attention Bitterly, chill holds wet headache under the arm；Chinese cassia tree complement sun, warming spleen and stomach, removing internal cold, promoting blood circulation；Grass of meadow rue has removing toxicity for detumescence, improving eyesight, antidiarrheal etc. Effect；Radix glycyrrhizae cures mainly clearing heat and detoxicating, expelling phlegm and arresting coughing, gastral cavity abdomen etc.；River Chinese herbaceous peony is used for alleviating pain；Honeysuckle can dispelling wind-heat, also Kind removing summer-heat blood poison；Peppermint is pungent cool property sweating antipyretic medicine, controls influenza, headache, hot eyes, body heat, throat, gum swelling and pain etc. Disease；It is windproof to expel pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, only the effect of convulsion；Notopterygium root is warm-natured, dispellieg cold and dampness, for catch cold, have a headache it is lossless, Cold-dampness numbness, upper limb rheumatalgia pain；Chrysanthemum has auxiliary therapeutic action to catching a cold, having a headache；Fructus Forsythiae can be detoxified, dissipating bind, disappears with heat-clearing It is swollen；Above-mentioned Chinese medicine is combined according to a certain percentage, there is stronger antipyretic effect, medicine produced by the present invention Composition is non-toxic, and curative effect is fast, is very suitable for Pediatric Clinic application, and convenient to take, and indication scope is wide, and side effect does not almost have Have, drug safety degree is high, and medicine source is sufficient, meets growing Pediatric Clinic needs and the market demand.
Embodiment
The present invention is made with reference to specific embodiment further to explain.
Embodiment one
A kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic proposed by the present invention, includes the raw material of following parts by weight：Bavin 3 parts recklessly, 1 part of rhizoma Gastrodiae, 0.2 part of Chinese ephedra, 3 parts of levisticum, 2 parts of Chinese cassia tree, 4 parts of grass of meadow rue, 1 part of radix glycyrrhizae, 6 parts of river Chinese herbaceous peony, 50 parts of honeysuckle, 4 parts of peppermint, 0.5 part windproof, 0.1 part of notopterygium root, 5 parts of chrysanthemum, 1 part of Fructus Forsythiae.
Its preparation method comprises the following steps：
S1, weighs radix bupleuri, rhizoma Gastrodiae, Chinese ephedra, levisticum, Chinese cassia tree, grass of meadow rue according to deal proportioning, above-mentioned raw materials is cleaned after drying in the shade, It is sequentially placed into mill and is fully ground, obtains mixed powder A；
S2, mixed powder A is put into cooker, is put into the water of 7 times of amounts, and first big fire decocts 0.5h, then small fire decocts 1h, filter residue, Obtain liquor B；
S3, weighs radix glycyrrhizae, river Chinese herbaceous peony, honeysuckle, peppermint, windproof, notopterygium root, chrysanthemum, Fructus Forsythiae according to deal proportioning, above-mentioned raw materials is washed Only it, dry, pulverize to 120 mesh, mix and be put into Decocting pot, the water of 6 times of amounts is put into, after big fire decocts 1h, by liquor B It is put into Decocting pot, decocts 1h with small fire, filter residue, obtains liquor C；
S4, will be filling after liquor C high-temperature sterilization, you can obtain a kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic.
Embodiment two
A kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic proposed by the present invention, includes the raw material of following parts by weight：Bavin 4 parts recklessly, 2 parts of rhizoma Gastrodiae, 0.3 part of Chinese ephedra, 5 parts of levisticum, 4 parts of Chinese cassia tree, 5 parts of grass of meadow rue, 3 parts of radix glycyrrhizae, 8 parts of river Chinese herbaceous peony, 7 parts of honeysuckle, 5 parts of peppermint, 1 part windproof, 0.4 part of notopterygium root, 7 parts of chrysanthemum, 3 parts of Fructus Forsythiae.
Its preparation method comprises the following steps：
S1, weighs radix bupleuri, rhizoma Gastrodiae, Chinese ephedra, levisticum, Chinese cassia tree, grass of meadow rue according to deal proportioning, above-mentioned raw materials is cleaned after drying in the shade, It is sequentially placed into mill and is fully ground, obtains mixed powder A；
S2, mixed powder A is put into cooker, is put into the water of 8 times of amounts, and first big fire decocts 0.6h, then small fire decocts 1.2h, filter Slag, obtains liquor B；
S3, weighs radix glycyrrhizae, river Chinese herbaceous peony, honeysuckle, peppermint, windproof, notopterygium root, chrysanthemum, Fructus Forsythiae according to deal proportioning, above-mentioned raw materials is washed Only it, dry, pulverize to 125 mesh, mix and be put into Decocting pot, be put into the water of 6.5 times of amounts, will after big fire decocts 1.5h Liquor B is put into Decocting pot, decocts 1.2h with small fire, filter residue, obtains liquor C；
S4, will be filling after liquor C high-temperature sterilization, you can obtain a kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic.
Embodiment three
A kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic proposed by the present invention, includes the raw material of following parts by weight：Bavin 6 parts recklessly, 3 parts of rhizoma Gastrodiae, 0.5 part of Chinese ephedra, 7 parts of levisticum, 7 parts of Chinese cassia tree, 7 parts of grass of meadow rue, 6 parts of radix glycyrrhizae, 10 parts of river Chinese herbaceous peony, honeysuckle 7.5 Part, 6 parts of peppermint, 1.5 parts windproof, 0.5 part of notopterygium root, 10 parts of chrysanthemum, 4 parts of Fructus Forsythiae.
Its preparation method comprises the following steps：
S1, weighs radix bupleuri, rhizoma Gastrodiae, Chinese ephedra, levisticum, Chinese cassia tree, grass of meadow rue according to deal proportioning, above-mentioned raw materials is cleaned after drying in the shade, It is sequentially placed into mill and is fully ground, obtains mixed powder A；
S2, mixed powder A is put into cooker, is put into the water of 9 times of amounts, and first big fire decocts 0.75h, then small fire decocts 1.5h, filter Slag, obtains liquor B；
S3, weighs radix glycyrrhizae, river Chinese herbaceous peony, honeysuckle, peppermint, windproof, notopterygium root, chrysanthemum, Fructus Forsythiae according to deal proportioning, above-mentioned raw materials is washed Only it, dry, pulverize to 130 mesh, mix and be put into Decocting pot, the water of 7 times of amounts is put into, after big fire decocts 2h, by liquor B It is put into Decocting pot, decocts 1.5h with small fire, filter residue, obtains liquor C；
S4, will be filling after liquor C high-temperature sterilization, you can obtain a kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic.
Example IV
A kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic proposed by the present invention, includes the raw material of following parts by weight：Bavin 7 parts recklessly, 5 parts of rhizoma Gastrodiae, 0.7 part of Chinese ephedra, 8 parts of levisticum, 10 parts of Chinese cassia tree, 8 parts of grass of meadow rue, 8 parts of radix glycyrrhizae, 12 parts of river Chinese herbaceous peony, honeysuckle 8 Part, 8 parts of peppermint, 2 parts windproof, 0.6 part of notopterygium root, 13 parts of chrysanthemum, 5 parts of Fructus Forsythiae.
Its preparation method comprises the following steps：
S1, weighs radix bupleuri, rhizoma Gastrodiae, Chinese ephedra, levisticum, Chinese cassia tree, grass of meadow rue according to deal proportioning, above-mentioned raw materials is cleaned after drying in the shade, It is sequentially placed into mill and is fully ground, obtains mixed powder A；
S2, mixed powder A is put into cooker, is put into the water of 10 times of amounts, and first big fire decocts 0.9h, then small fire decocts 1.8h, filter Slag, obtains liquor B；
S3, weighs radix glycyrrhizae, river Chinese herbaceous peony, honeysuckle, peppermint, windproof, notopterygium root, chrysanthemum, Fructus Forsythiae according to deal proportioning, above-mentioned raw materials is washed Only it, dry, pulverize to 135 mesh, mix and be put into Decocting pot, be put into the water of 7.5 times of amounts, will after big fire decocts 2.5h Liquor B is put into Decocting pot, decocts 1.8h with small fire, filter residue, obtains liquor C；
S4, will be filling after liquor C high-temperature sterilization, you can obtain a kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic.
Embodiment five
A kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic proposed by the present invention, includes the raw material of following parts by weight：Bavin 8 parts recklessly, 6 parts of rhizoma Gastrodiae, 0.8 part of Chinese ephedra, 10 parts of levisticum, 12 parts of Chinese cassia tree, 9 parts of grass of meadow rue, 10 parts of radix glycyrrhizae, 14 parts of river Chinese herbaceous peony, honeysuckle 10 parts, 9 parts of peppermint, 3 parts windproof, 1 part of notopterygium root, 15 parts of chrysanthemum, 7 parts of Fructus Forsythiae.
Its preparation method comprises the following steps：
S1, weighs radix bupleuri, rhizoma Gastrodiae, Chinese ephedra, levisticum, Chinese cassia tree, grass of meadow rue according to deal proportioning, above-mentioned raw materials is cleaned after drying in the shade, It is sequentially placed into mill and is fully ground, obtains mixed powder A；
S2, mixed powder A is put into cooker, is put into the water of 11 times of amounts, and first big fire decocts 1h, then small fire decocts 2h, and filter residue, obtains To liquor B；
S3, weighs radix glycyrrhizae, river Chinese herbaceous peony, honeysuckle, peppermint, windproof, notopterygium root, chrysanthemum, Fructus Forsythiae according to deal proportioning, above-mentioned raw materials is washed Only it, dry, pulverize to 140 mesh, mix and be put into Decocting pot, the water of 8 times of amounts is put into, after big fire decocts 3h, by liquor B It is put into Decocting pot, decocts 2h with small fire, filter residue, obtains liquor C；
S4, will be filling after liquor C high-temperature sterilization, you can obtain a kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic.
In order to examine the present invention drug effect, by the present invention with aspirin contrast, therapeutic effect be divided into significantly effectively, have Effect, invalid, comparing result such as following table：
Group Number of cases Remarkable result Effectively It is invalid Total effective rate
The present invention 100 67 29 4 96%
Aspirin 100 43 31 26 74%
As seen from the above table, the present invention has stronger antipyretic effect, and curative effect is high.
The foregoing is only a preferred embodiment of the present invention, but protection scope of the present invention be not limited thereto, Any one skilled in the art the invention discloses technical scope in, technique according to the invention scheme and its Inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.

Claims (8)

1. a kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic, it is characterised in that include the raw material of following parts by weight：Bavin 3-8 parts of Hu, 1-6 parts of rhizoma Gastrodiae, 0.2-0.8 parts of Chinese ephedra, 3-10 parts of levisticum, 2-12 parts of Chinese cassia tree, 4-9 parts of grass of meadow rue, 1-10 parts of radix glycyrrhizae, Chinese herbaceous peony 6-14 parts of river, 5-10 parts of honeysuckle, 4-9 parts of peppermint, 0.5-3 parts windproof, 0.1-1 parts of notopterygium root, 5-15 parts of chrysanthemum, Fructus Forsythiae 1-7 Part.
A kind of 2. pharmaceutical composition for pediatric hospital antipyretic-antalgic according to claim 1, it is characterised in that including The raw material of following parts by weight：4-7 parts of radix bupleuri, 2-5 parts of rhizoma Gastrodiae, 0.3-0.7 parts of Chinese ephedra, 5-8 parts of levisticum, 4-10 parts of Chinese cassia tree, Tang Song 5-8 parts careless, 3-8 parts of radix glycyrrhizae, Chinese herbaceous peony 8-12 parts of river, 7-8 parts of honeysuckle, 5-8 parts of peppermint, 1-2 parts windproof, 0.4-0.6 parts of notopterygium root, chrysanthemum Flower 7-13 parts, 3-5 parts of Fructus Forsythiae.
A kind of 3. pharmaceutical composition for pediatric hospital antipyretic-antalgic according to claim 1, it is characterised in that including The raw material of following parts by weight：6 parts of radix bupleuri, 3 parts of rhizoma Gastrodiae, 0.5 part of Chinese ephedra, 7 parts of levisticum, 7 parts of Chinese cassia tree, 7 parts of grass of meadow rue, 6 parts of radix glycyrrhizae, 10 parts of river Chinese herbaceous peony, 7.5 parts of honeysuckle, 6 parts of peppermint, 1.5 parts windproof, 0.5 part of notopterygium root, 10 parts of chrysanthemum, 4 parts of Fructus Forsythiae.
4. a kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic according to claim 1, it is characterised in that described Radix bupleuri, rhizoma Gastrodiae, the weight ratio of Chinese ephedra are 4-7：2-5：0.3-0.7.
5. a kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic according to claim 1, it is characterised in that described Levisticum, Chinese cassia tree, the weight ratio of grass of meadow rue are 5-8：4-10：5-8.
6. a kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic according to claim 1, it is characterised in that described Radix glycyrrhizae, river Chinese herbaceous peony, the weight ratio of honeysuckle are 3-8：8-12：7-8.
7. a kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic according to claim 1, it is characterised in that described The preparation method of pharmaceutical composition comprises the following steps：
S1, weighs radix bupleuri, rhizoma Gastrodiae, Chinese ephedra, levisticum, Chinese cassia tree, grass of meadow rue according to deal proportioning, above-mentioned raw materials is cleaned after drying in the shade, It is sequentially placed into mill and is fully ground, obtains mixed powder A；
S2, mixed powder A is put into cooker, is put into the 7-11 times of water measured, and first big fire decocts 0.5-1h, then small fire decocts 1- 2h, filter residue, obtains liquor B；
S3, weighs radix glycyrrhizae, river Chinese herbaceous peony, honeysuckle, peppermint, windproof, notopterygium root, chrysanthemum, Fructus Forsythiae according to deal proportioning, above-mentioned raw materials is washed Only it, dry, pulverize to 120-140 mesh, mix and be put into Decocting pot, be put into the 6-8 times of water measured, big fire decocts 1-3h Afterwards, liquor B is put into Decocting pot, decocts 1-2h with small fire, filter residue, obtains liquor C；
S4, will be filling after liquor C high-temperature sterilization, you can obtain a kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic.
A kind of 8. pharmaceutical composition for pediatric hospital antipyretic-antalgic according to claim 1 or 7, it is characterised in that In the S2, mixed powder A is put into cooker, is put into the water of 9 times of amounts, first big fire decocts 0.75h, then small fire decocts 1.5h, Filter residue, obtains liquor B.
CN201711281025.3A 2017-12-07 2017-12-07 A kind of pharmaceutical composition for pediatric hospital antipyretic-antalgic Pending CN107929562A (en)

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Publication number Priority date Publication date Assignee Title
CN102784282A (en) * 2012-08-27 2012-11-21 郑州同心堂生物科技有限公司 Medicine for clearing heat, removing toxicity and reducing fever
CN104857084A (en) * 2015-06-11 2015-08-26 公安县中医医院 Traditional Chinese medicine medicated bath preparation for treating infantile exogenous fever
CN105343174A (en) * 2015-12-15 2016-02-24 郑州莉迪亚医药科技有限公司 Traditional Chinese medicine for treating influenza

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Publication number Priority date Publication date Assignee Title
CN102784282A (en) * 2012-08-27 2012-11-21 郑州同心堂生物科技有限公司 Medicine for clearing heat, removing toxicity and reducing fever
CN104857084A (en) * 2015-06-11 2015-08-26 公安县中医医院 Traditional Chinese medicine medicated bath preparation for treating infantile exogenous fever
CN105343174A (en) * 2015-12-15 2016-02-24 郑州莉迪亚医药科技有限公司 Traditional Chinese medicine for treating influenza

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