CN107929550A - It is a kind of protect, the activity gels of renovating tummy mucous membrane and preparation method thereof - Google Patents
It is a kind of protect, the activity gels of renovating tummy mucous membrane and preparation method thereof Download PDFInfo
- Publication number
- CN107929550A CN107929550A CN201810033402.XA CN201810033402A CN107929550A CN 107929550 A CN107929550 A CN 107929550A CN 201810033402 A CN201810033402 A CN 201810033402A CN 107929550 A CN107929550 A CN 107929550A
- Authority
- CN
- China
- Prior art keywords
- weight
- parts
- bletilla
- activity gels
- alcohol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/739—Sanguisorba (burnet)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Rheumatology (AREA)
- Inorganic Chemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Marine Sciences & Fisheries (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Neurosurgery (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to it is a kind of protect, the activity gels of renovating tummy mucous membrane and preparation method thereof, belong to Chinese medicine health-care field.Its raw material includes bletilla, cornu cerve degelatinatum, garden burnet skin, Sculellaria barbata, rhizoma nelumbinis, Radix Paeoniae Alba, Rhizoma Atractylodis Macrocephalae, pseudo-ginseng, Chinese yam, raddle, betel nut, hairyvein agrimony, pueraria lobata and pearl.Above-mentioned raw materials are enriched and matched proper, can not only comprehensive raising gastrointestinal function, increase it to act on intestines and stomach noxious substance, cuticula sore, and have good treatment and repair to the various inflammation and mucosa injury of oral cavity, esophagus, stomach and intestines, in addition, bioavilability can also be improved, dose is reduced, saving Chinese medicaments resource, reduces the toxic side effect of Chinese medicine.Preparation method includes：Raw material in addition to bletilla is pulverized, extracts bletilla glue, the powder particle after bletilla glue and grinding is mixed, steams and shine, disinfection.This method is simple, and pharmaceutical activity reserving degree is high.
Description
Technical field
The present invention relates to Chinese medicine health-care field, and more particularly to a kind of protection, the activity gels and its system of renovating tummy mucous membrane
Preparation Method.
Background technology
Gastrointestinal disease is one of disease most commonly seen in life, and the World Health Organization counts discovery in recent years, and gastrointestinal disease exists
Incidence in crowd is up to 80%, and is just increased with annual 17.43% speed.Investigation is found in the world, entirely
Ball dies of the number of gastrointestinal disease more than 10,000,000 every year, and the people that China has 4/5 suffers from gastrointestinal disease, occupies first place in the world.It is if anxious
Property the long-term protracted course of disease of gastrointestinal disease be transformed into Chronic gastrointestinal disorders, long-term chronic disease to produce harmful bacteria secretion poison in vivo
Element, corrupt substance increases in intestines and stomach, attacks gastrointestinal mucosa, mucosal erosion, ulcer, or even denaturation and is further development of cancer.
Gastrointestinal disease directly affects human condition and quality of life as clinical common, frequently-occurring disease, treatment and prognosis,
Therefore countries in the world physician actively inquires into the treatment method of gastrointestinal disease, to develop the specific medicament for the treatment of gastrointestinal disease.
The content of the invention
It is an object of the present invention to provide it is a kind of protect, the activity gels of renovating tummy mucous membrane, its abundant raw material and match somebody with somebody
Than proper, can not only comprehensive raising gastrointestinal function, increase its to intestines and stomach noxious substance act on, cuticula sore, and
There are good treatment and repair to the various inflammation and mucosa injury of oral cavity, esophagus, stomach and intestines, moreover it is possible to improve
Bioavilability, reduces dose, saving Chinese medicaments resource, reduces the toxic side effect of Chinese medicine.
The second object of the present invention is to provide a kind of preparation method of above-mentioned activity gels, and this method is simple, and medicine is lived
Property reserving degree it is high.
The present invention is solved its technical problem and is realized using following technical scheme：
The present invention proposes a kind of protection, the activity gels of renovating tummy mucous membrane, its raw material includes bletilla, the 2-6 of 2-6 parts by weight
The cornu cerve degelatinatum of parts by weight, the garden burnet skin of 2-6 parts by weight, the Sculellaria barbata of 2-6 parts by weight, the rhizoma nelumbinis of 2-6 parts by weight, 1-5 parts by weight
Radix Paeoniae Alba, the Rhizoma Atractylodis Macrocephalae of 1-5 parts by weight, the pseudo-ginseng of 1-5 parts by weight, the Chinese yam of 1-5 parts by weight, 0.5-4 parts by weight raddle,
The betel nut of 0.5-4 parts by weight, the hairyvein agrimony of 0.5-4 parts by weight, the pearl of the pueraria lobata of 0.5-4 parts by weight and 0.2-2 parts by weight.
The invention also provides a kind of preparation method of above-mentioned activity gels, comprise the following steps：By cornu cerve degelatinatum, garden burnet
Skin, Sculellaria barbata, rhizoma nelumbinis, Radix Paeoniae Alba, Rhizoma Atractylodis Macrocephalae, pseudo-ginseng, Chinese yam, raddle, betel nut, hairyvein agrimony, pueraria lobata and pearl are pulverized, extraction
Bletilla glue, mixes the powder particle of gained after bletilla glue and grinding, steams and shine, disinfection.
The beneficial effect of the protection of the embodiment of the present invention, the activity gels of renovating tummy mucous membrane and preparation method thereof is：
1) protection provided in an embodiment of the present invention, the activity gels of renovating tummy mucous membrane can significantly improve the treatment of traditional Chinese medicine
Effect, improves bioavilability, reduces dose, saving Chinese medicaments resource, reduces the toxic side effect of Chinese medicine.
2) protection provided in an embodiment of the present invention, the activity gels of renovating tummy mucous membrane can maintain Chinese medicine genuine, and nothing is appointed
What additive, has no toxic side effect.
3) protection provided in an embodiment of the present invention, the activity gels of renovating tummy mucous membrane are suitable for various crowds, carry, take
It is convenient.
4) protection provided in an embodiment of the present invention, the activity gels of renovating tummy mucous membrane will be by that to gastrointestinal effect and will contain big
The Chinese medicine of amount tanning and mucilage makes gel, hence it is evident that increases it and intestines and stomach noxious substance is acted on, strengthen its cuticula and hold back
Sore acts on.
5) it is provided in an embodiment of the present invention protection, renovating tummy mucous membrane activity gels to oral cavity, esophagus, stomach, intestines it is various
Inflammation and mucosa injury have good treatment and repair, form comprehensive raising gastrointestinal function, cuticula sore it is new
Product.
Embodiment
, below will be in the embodiment of the present invention to make the purpose, technical scheme and advantage of the embodiment of the present invention clearer
Technical solution be clearly and completely described.The person that is not specified actual conditions in embodiment, builds according to normal condition or manufacturer
The condition of view carries out.Reagents or instruments used without specified manufacturer, is the conventional production that can be obtained by commercially available purchase
Product.
Protection to the embodiment of the present invention below, the activity gels and preparation method thereof of renovating tummy mucous membrane carry out specifically
It is bright.
Since the big multiaction of the medicine of modern clinical treatment enterogastric diseases is single, it is impossible to which stomach and intestine are same to be controlled, and is clinically repaiied
The medicine of multiple intestinal mucosa is very few.But stomach and intestine patient, the same disease of most stomach and intestine, therefore the activity gels in the embodiment of the present invention
Mainly by stomach and intestine with controlling, repair stomach and intestine and be damaged the mode of mucous membrane to have the function that protection, renovating tummy mucous membrane.
Optionally, the raw material of the activity gels in the embodiment of the present invention for example can include 2-6 parts by weight bletilla,
The cornu cerve degelatinatum of 2-6 parts by weight, the garden burnet skin of 2-6 parts by weight, the Sculellaria barbata of 2-6 parts by weight, the rhizoma nelumbinis of 2-6 parts by weight, 1-5 weight
Part Radix Paeoniae Alba, the Rhizoma Atractylodis Macrocephalae of 1-5 parts by weight, the pseudo-ginseng of 1-5 parts by weight, the Chinese yam of 1-5 parts by weight, 0.5-4 parts by weight raddle,
The betel nut of 0.5-4 parts by weight, the hairyvein agrimony of 0.5-4 parts by weight, the pearl of the pueraria lobata of 0.5-4 parts by weight and 0.2-2 parts by weight.
Further, above-mentioned raw materials include the bletilla of 3-5 parts by weight, the cornu cerve degelatinatum of 3-5 parts by weight, the ground of 3-5 parts by weight
Elm skin, the Sculellaria barbata of 3-5 parts by weight, the rhizoma nelumbinis of 3-5 parts by weight, the Radix Paeoniae Alba of 2-4 parts by weight, the Rhizoma Atractylodis Macrocephalae of 2-4 parts by weight, 2-4 weights
Measure the pseudo-ginseng of part, the Chinese yam of 2-4 parts by weight, the raddle of 1.5-3 parts by weight, the betel nut of 1.5-3 parts by weight, 1.5-3 parts by weight
Hairyvein agrimony, the pueraria lobata of 1.5-3 parts by weight and the pearl of 0.8-1.2 parts by weight.
Further, above-mentioned raw materials include the bletilla of 4 parts by weight, the cornu cerve degelatinatum of 4 parts by weight, 4 parts by weight garden burnet skin,
The Sculellaria barbata of 4 parts by weight, the rhizoma nelumbinis of 4 parts by weight, the Radix Paeoniae Alba of 3 parts by weight, the Rhizoma Atractylodis Macrocephalae of 3 parts by weight, the pseudo-ginseng of 3 parts by weight, 3 weight
The Chinese yam of part, the raddle of 2 parts by weight, the betel nut of 2 parts by weight, the hairyvein agrimony of 2 parts by weight, the pueraria lobata and 1 weight of 2 parts by weight
The pearl of part.
Above-mentioned raw materials containing a large amount of mucilages, tannin composition, can play the role of detoxication and toxicant eliminating function and cuticula is cured sore.This
Outside, above-mentioned raw materials have higher nutriture value also containing the trace element such as abundant vitamin, amino acid and calcium, magnesium, iron, zinc
Value.
Wherein, bletilla contains the components such as colloid and starch, has convergence myogenic, detumescence hemostasis, resisting pathogenic microbes, corruption of dispelling
Myogenic, adjust the effects such as immune, hemostasis, antitumor and promotion organization healing.Carried in the embodiment of the present invention as medicine
Body, so that activity gels have the characteristics that slow release, local retention, good biocompatibility and auto-degradation.
Chinese yam containing diosgenin, mucilaginous substance, choline, starch, glycoprotein, free amino acid, only wooden fork element, vitamin C and
Amylase etc., it is full of nutrition, and easily digestion, there is the effect of tonifying spleen lung kidney qi, strengthening spleen and lung kidney yin.
Sculellaria barbata has clearing heat and detoxicating and scattered stasis pain and other effects, to lung cancer, Alimentary System, breast cancer and chorioepithelium
Cancer has certain resistant function.
Pseudo-ginseng contains the compositions such as pseudo-ginseng propylhomoserin, saponin(e, flavonoid glycoside and amino acid, and there is removing blood stasis and hemostasis, promoting blood circulation, detumescence to stop
Bitterly, qi-restoratives and other effects, is chiefly used in treating out the diseases such as blood trouble, traumatic injury, blood stasis and swelling pain.
Hairyvein agrimony contains the compositions such as phloroglucin condensation body, flavones, agrimonine, colloid, organic acid compound, has
The effect of astringing to arrest bleeding, preventing malaria, qi-restoratives stop dysentery, be chiefly used in the diseases such as blood trouble, diarrhea, dysentery, de-power internal lesion caused by overexertion.It is clinically main
Treatment for the diseases such as uropoiesis, breathing, digestive system and gynecological disease.
Cornu cerve degelatinatum for deer horn boil rear remaining bone slag, phosphoric acid calcium, colloid, amino acid, calcium carbonate and nitride etc. into
Part, the effect of its is sweet in flavor, nontoxic, belongs to the medicine of slow benefits, supporing yang with kidney-nourishing, astringing to arrest bleeding, activating blood circulation and reducing swelling, can control deficiency-cold in spleen and stomach,
The insufficiency of the kidney yang, ulcer subcutaneous nodule, sore such as do not hold back at the disease.It not only can strengthen immunity, moreover it is possible to which dredging collateral eliminating evil, makes qi and blood and smooth.
Pearl contains abundant amino acid, mineral matter and trace element, while also contains high-activity biological taurine and rich
Rich pearl protein, can improve the activity of flight against senium of human body factor S OD and amino acid carrier GSH-PX, with arresting convulsion of calming the nerves, clearly
The effect of thermal detoxification, soothing the liver protect liver, coordinating intestines and stomach, supplement calcium system, microelement-supplementing；At the same time its can also delaying skin aging,
Human endocrine is adjusted, boosts metabolism and strengthens the multiple functions such as immunity of organisms.In addition, pearl also has extremely strong suction
Attached characteristic, adsorbable intestines and stomach harmful substance, excretes.
The compositions such as pueraria lobata daidzein containing Flavonoid substances, daidzin, Puerarin, there is expelling pathogenic factors from muscles and skin to bring down a fever, Shengyang Zhixie, promote the production of body fluid
Quench the thirst and other effects, be mainly used for pyreticosis polydipsia, Heat Diabetes, heat expels the heat-evil the treatment of the disease such as dysentery, insufficiency of the spleen chronic diarrhea.
Rhizoma nelumbinis has tonifying-Yin and nourishing-stomach, cooling blood and hemostasis, stagnation resolvation and astringing to arrest bleeding containing material compositions such as tannin, amino acid, starch
The effect of.
Each raw material of activity gels provided in an embodiment of the present invention both individually acted on, while also mutually acted synergistically, with
Comprehensive raising gastrointestinal function.
Each raw material can each serve as following effect：Anti-inflammatory：Such as Sculellaria barbata；Analgesic：Such as cornu cerve degelatinatum and pseudo-ginseng；Relieving haperacidity：Such as treasure
Pearl；Sore：Such as bletilla；Promote cell migration：Garden burnet skin and rhizoma nelumbinis；Improve gastroenteritic power：Such as Radix Paeoniae Alba and Rhizoma Atractylodis Macrocephalae；It is thin to adsorb enteral
Bacterium and metabolite：Such as pearl and pueraria lobata；Antifatigue anti senility：Hairyvein agrimony and Chinese yam；Promote gastrointestinal emptying：Raddle and Bin
It is bulky.
Synergistic effect then mainly focus on heat-clearing by the overall uniformity from stomach and intestine, chronic disease pathogen usually intruding into collateral in protracted disease grade, medication
Removing toxic substances, ventilation quality, logical mend combine, and simultaneously using both cold and hot drugs, take weighing apparatus as degree, stomach and intestine with control, the stomach and intestine people having the same aspiration and interest, and with " detoxication and toxicant eliminating function,
Promote gastrointestinal peristalsis, improve gastrointestinal emptying, Conservative restoration gastrointestinal mucosa " quaternity therapy, it is harmful to thoroughly removing intestines and stomach
Material, restoration and protection gastrointestinal mucosa, improves and recovers to improve gastrointestinal function, so as to improve human body constitution, fundamentally solve comprehensively
The problem of gastrointestinal tract mucosa is damaged.
Specifically, " detoxication and toxicant eliminating function " mainly plays heat-clearing solution by formulas such as the cornu cerve degelatinatum in raw material, Sculellaria barbata and Chinese herbaceous peonies
The effect of poison and supplementing qi and nourishing yin." promotion gastrointestinal peristalsis " mainly passes through fortune of the Rhizoma Atractylodis Macrocephalae to play the emptying of promotion stomach and promote small intestine
The effect of dynamic speed." raising gastrointestinal emptying " is mainly coordinated by raddle, pseudo-ginseng, pueraria lobata, hairyvein agrimony and Chinese yam etc., on the one hand
Gastrointestinal peristalsis can be improved, another aspect liftable is interdependent, and reinforcing and reducing methods is harmonious, and bowl spares, which has, rushes down, and has drop in liter, makes the stomach and intestine coordinated movement of various economic factors,
So as to avoid harmful substance from entering stomach, promote gastrointestinal emptying, prevent further infringement of the turbidity to gastrointestinal mucosa." Conservative restoration
Gastrointestinal mucosa " changes mainly by raw materials such as bletilla, garden burnet skin, rhizoma nelumbinis, pseudo-ginseng, pearl and pueraria lobatas to repair impaired gastrointestinal mucosa
The blood circulation of kind ulcer surface, strengthens its nutrition, promotes sore to be cured.
In conclusion in the embodiment of the present invention protection, renovating tummy mucous membrane activity gels Medicinal Trait be divided into control, repair,
Shield, support.Control：Sculellaria barbata, pseudo-ginseng, Radix Paeoniae Alba and cornu cerve degelatinatum etc. have heat-clearing sterilization, anti inflammatory blood quickening, improve gastrointestinal mucosa microcirculation,
Caused gastrointestinal tract mucosa injury is repaired, heal ulcer surface, quickly improves the symptoms such as abdominal pain, diarrhea.Repair：Garden burnet skin, rhizoma nelumbinis and bletilla etc.
Medicine is used to treat injury of gastrointestinal tract disease, can substantially repair the gastrointestinal mucosa of damage, improves symptom of digestive tract.Shield：Radix Paeoniae Alba, treasure
Pearl, Rhizoma Atractylodis Macrocephalae and raddle etc. are used to treat disease of digestive tract, and can go directly gastrointestinal mucosa, have and promote stomach and intestine evacuating pipeline, and reduction has
Evil material sticks stomach and intestine to be damaged again, and eliminating evil is without hindering just.Support：Hairyvein agrimony, betel nut, pueraria lobata and Chinese yam in prescription etc. are empty to taste
It is weak and gastrointestinal function decline occurred by medicine irritation for a long time, improvement can be nourished comprehensively, improve gastroenteritic power；While above-mentioned raw materials are also
With intestines and stomach absorption function is improved, make the histocyte Regeneration and Repair of atrophy, it is rapid to improve intestines and stomach immunity, strengthen stomach and intestine
The disease resistance in road.
In addition, additionally providing the preparation method of above-mentioned activity gels in the embodiment of the present invention, comprise the following steps：By deer horn
Frost, garden burnet skin, Sculellaria barbata, rhizoma nelumbinis, Radix Paeoniae Alba, Rhizoma Atractylodis Macrocephalae, pseudo-ginseng, Chinese yam, raddle, betel nut, hairyvein agrimony, pueraria lobata and pearl are ground into
Powder, extracts bletilla glue, mixes the powder particle of gained after bletilla glue and grinding, steams and shine, disinfection.
Optionally, the granularity of the powder particle of gained for example can be 65-100 mesh after above-mentioned grinding.Preferably, on
State in powder particle at least containing 3 kinds of different granularities.Medicine is made the particulate of different-diameter, it is mainly due to different size
Drug microparticles after intestines and stomach are entered, the tiny medicine of particulate is attached on gastrointestinal mucosa first, plays a role, medium and big
Particulate smoothly enters enteron aisle, stimulates function of intestinal canal.Therefore, can basis by the way that drug component raw material to be ground into different granularities
Stomach and intestine different parts are different to the absorptivity of different size of medicine, to extend the mass rate of emission of each medicine in the gastrointestinal tract, carry
The bioactivity and utilization rate of high medicine.
Optionally, bletilla glue can for example obtain in the following manner：Bletilla is extracted at least 48h in water, will be soaked
Extract mixes at least 24h with alcohol, and filtering, collects sediment.Preferably, above-mentioned alcohol includes ethanol.
It is preferred that in the embodiment of the present invention, extraction includes the first leaching stages and the second leaching stages, the first leaching stages
It is that 10-15h is extracted under conditions of room temperature (10-30 DEG C), the second leaching stages are extracted at least under conditions of 50-60 DEG C
38h.Why will extract that to be divided into two stages be in view of a variety of active ingredients contained in bletilla is under condition of different temperatures
The characteristics of leaching rate is different and design.First leaching stages be mainly used for extraction in water the big bletilla activity of solubility into
Point, this leaching stages is to operating environment without particular/special requirement.Second leaching stages are mainly by improving temperature, to promote in bletilla
The slightly worse active ingredient molecule movement of solubility is more active in water, so as to improve dissolution rate.
, can be more only under conditions of room temperature (10-30 DEG C) or only in 50-60 DEG C by the way that extraction is divided into the above-mentioned two stage
Under conditions of extraction significantly improve the extraction yield (34-51% and 28-37% is respectively increased) of bletilla active material, and can also
Substantially reduce extraction cost.
Optionally, the volume ratio of alcohol and leaching liquor such as can be 10-20：4-6.It is preferred that above-mentioned alcohol contains at the same time
There are ethanol, propyl alcohol and a propane diols, the mass percent of ethanol is 40-50wt% in alcohol.Preferably, ethanol, propyl alcohol and propane diols
Volume ratio be 40-50：10-20：20-25.
Through experiment, propyl alcohol and propane diols are added in ethanol collectively as stand-by alcohol, it can be by the active material in bletilla
Rate of deposition relatively be used only ethanol in the case of improve 10-12%, make the rate of deposition of active material up to more than 90%, so that significantly
Improve the utilization rate of bletilla.
Further, steaming solarization is carried out to mixed medicine, to mitigate the toxic side effect of medicine, strengthens the affine energy of stomach and intestine
Power.
Further, the disinfection in the present embodiment is carried out under the conditions of existing for Co 60, on the one hand can be ensured efficiently
Disinfection Effect, on the other hand be also avoided that caused in disinfecting process active constituents of medicine inactivate phenomenon.
From the above, the present invention uses bioactivity gel new ant algorithms, can effectively make up traditional Chinese herbal decoction mouthfeel hardship, dose
Big and pill matter is hard, works the shortcomings of slow, and gel preparations have good biocompatibility, have to insoluble drug release be sustained,
Controlled-release function, applied to having good therapeutic effect in disease of digestive tract diagnosis and treatment.Also, jelly is simple for production, plus-minus is flexible, adaptive surface
Extensively.
The feature and performance of the present invention are described in further detail with reference to embodiments.
Embodiment 1
The bletilla of 2 parts by weight is extracted into 15h under conditions of 10 DEG C, then extracts 38h under conditions of 50 DEG C.Will extraction
Liquid is with alcohol using volume ratio as 10：4 mixing 24h, filtering, collects sediment, obtains bletilla glue.Wherein, alcohol is at the same time containing 40wt%'s
The propane diols of ethanol, the propyl alcohol of 10wt% and 20wt%.
By the cornu cerve degelatinatum of 2 parts by weight, the garden burnet skin of 2 parts by weight, the Sculellaria barbata of 2 parts by weight, the rhizoma nelumbinis of 2 parts by weight, 1 weight
The Radix Paeoniae Alba of part, the Rhizoma Atractylodis Macrocephalae of 1 parts by weight, the pseudo-ginseng of 1 parts by weight, the Chinese yam of 1 parts by weight, the raddle of 0.5 parts by weight, 0.5 weight
Part betel nut, the hairyvein agrimony of 0.5 parts by weight, the pearl of the pueraria lobata of 0.5 parts by weight and 0.2 parts by weight pulverize.Above-mentioned grinding
The granularity of the powder particle of gained includes 65 mesh, 80 mesh and 100 mesh afterwards.
The powder particle of gained, steams and shines, then sterilize, obtain under the conditions of existing for Co 60 after mixing bletilla glue and grinding
Protection, the activity gels of renovating tummy mucous membrane.
Embodiment 2
The bletilla of 6 parts by weight is extracted into 10h under conditions of 30 DEG C, then extracts 45h under conditions of 60 DEG C.Will extraction
Liquid is with alcohol using volume ratio as 20：6 mixing 32h, filtering, collects sediment, obtains bletilla glue.Wherein, alcohol is at the same time containing 50wt%'s
The propane diols of ethanol, the propyl alcohol of 20wt% and 25wt%.
By the cornu cerve degelatinatum of 6 parts by weight, the garden burnet skin of 6 parts by weight, the Sculellaria barbata of 6 parts by weight, the rhizoma nelumbinis of 6 parts by weight, 5 weight
Part Radix Paeoniae Alba, the Rhizoma Atractylodis Macrocephalae of 5 parts by weight, the pseudo-ginseng of 5 parts by weight, the Chinese yams of 5 parts by weight, the raddle of 4 parts by weight, 4 parts by weight
Betel nut, the hairyvein agrimony of 4 parts by weight, the pearl of the pueraria lobata of 4 parts by weight and 2 parts by weight are pulverized.The powder of gained after above-mentioned grinding
The granularity of last particulate includes 65 mesh, 70 mesh, 80 mesh and 100 mesh.
The powder particle of gained, steams and shines, then sterilize, obtain under the conditions of existing for Co 60 after mixing bletilla glue and grinding
Protection, the activity gels of renovating tummy mucous membrane.
Embodiment 3
The bletilla of 3 parts by weight is extracted into 14h under conditions of 15 DEG C, then extracts 48h under conditions of 52.5 DEG C.Will leaching
Extract is with alcohol using volume ratio as 12.5：5.5 mixing 30h, filtering, collects sediment, obtains bletilla glue.Wherein, alcohol contains at the same time
The propane diols of the ethanol of 42.5wt%, the propyl alcohol of 17.5wt% and 20wt%.
By the cornu cerve degelatinatum of 5 parts by weight, the garden burnet skin of 3 parts by weight, the Sculellaria barbata of 5 parts by weight, the rhizoma nelumbinis of 3 parts by weight, 4 weight
The Radix Paeoniae Alba of part, the Rhizoma Atractylodis Macrocephalae of 2 parts by weight, the pseudo-ginseng of 4 parts by weight, the Chinese yam of 2 parts by weight, the raddle of 3 parts by weight, 1.5 parts by weight
Betel nut, the hairyvein agrimony of 3 parts by weight, the pearl of the pueraria lobata of 1.5 parts by weight and 1.2 parts by weight pulverize.Institute after above-mentioned grinding
The granularity of the powder particle obtained includes 70 mesh, 80 mesh, 90 mesh and 100 mesh.
The powder particle of gained, steams and shines, then sterilize, obtain under the conditions of existing for Co 60 after mixing bletilla glue and grinding
Protection, the activity gels of renovating tummy mucous membrane.
Embodiment 4
The bletilla of 5 parts by weight is extracted into 12h under conditions of 25 DEG C, then extracts 40h under conditions of 57.5 DEG C.Will leaching
Extract is with alcohol using volume ratio as 17.5：4.5 mixing 28h, filtering, collects sediment, obtains bletilla glue.Wherein, alcohol contains at the same time
The propane diols of the ethanol of 47.5wt%, the propyl alcohol of 12.5wt% and 25wt%.
By the cornu cerve degelatinatum of 3 parts by weight, the garden burnet skin of 5 parts by weight, the Sculellaria barbata of 3 parts by weight, the rhizoma nelumbinis of 5 parts by weight, 2 weight
The Radix Paeoniae Alba of part, the Rhizoma Atractylodis Macrocephalae of 4 parts by weight, the pseudo-ginseng of 2 parts by weight, the Chinese yam of 4 parts by weight, the raddle of 1.5 parts by weight, 3 parts by weight
Betel nut, the hairyvein agrimony of 1.5 parts by weight, the pearl of the pueraria lobata of 3 parts by weight and 0.8 parts by weight pulverize.Institute after above-mentioned grinding
The granularity of the powder particle obtained includes 65 mesh, 70 mesh, 75 mesh, 80 mesh, 90 mesh and 100 mesh.
The powder particle of gained, steams and shines, then sterilize, obtain under the conditions of existing for Co 60 after mixing bletilla glue and grinding
Protection, the activity gels of renovating tummy mucous membrane.
Embodiment 5
The bletilla of 4 parts by weight is extracted into 12.5h under conditions of 20 DEG C, then extracts 40h under conditions of 55 DEG C.Will leaching
Extract is with alcohol using volume ratio as 15：5 mixing 30h, filtering, collects sediment, obtains bletilla glue.Wherein, alcohol contains 45wt% at the same time
Ethanol, the propyl alcohol of 15wt% and the propane diols of 22.5wt%.
By the cornu cerve degelatinatum of 4 parts by weight, the garden burnet skin of 4 parts by weight, the Sculellaria barbata of 4 parts by weight, the rhizoma nelumbinis of 4 parts by weight, 3 weight
Part Radix Paeoniae Alba, the Rhizoma Atractylodis Macrocephalae of 3 parts by weight, the pseudo-ginseng of 3 parts by weight, the Chinese yams of 3 parts by weight, the raddle of 2 parts by weight, 2 parts by weight
Betel nut, the hairyvein agrimony of 2 parts by weight, the pearl of the pueraria lobata of 2 parts by weight and 1 parts by weight are pulverized.The powder of gained after above-mentioned grinding
The granularity of last particulate includes 65 mesh, 70 mesh, 75 mesh, 80 mesh, 85 mesh, 90 mesh, 95 mesh and 100 mesh.
The powder particle of gained, steams and shines, then sterilize, obtain under the conditions of existing for Co 60 after mixing bletilla glue and grinding
Protection, the activity gels of renovating tummy mucous membrane.
Test example
Above-described embodiment 1-5 is repeated, obtains enough protections, the activity gels of renovating tummy mucous membrane.
(1), the protection to gained, the activity gels of renovating tummy mucous membrane carry out treatment chronic gastritis (600) efficacy analysis
Experiment.
This group of case is disappeared with clinical symptoms, microscopy is normal for healing；Clinical symptoms disappear substantially and major part disappears
Lose, microscopy improvement is effective；Clinical symptoms without be clearly better, microscopy it is unchanged to be invalid.
Instructions of taking：Everyone each Orally active gel 5.5g, 3 times a day, is tuned into athero- or is heated in milk pot after meal
Patent medicine congee is taken.
As a result：600 are controlled, after l-2 agent of taking medicine, stool is thinning, and number has different degrees of increase, and symptom also subtracts therewith
Gently.Most short 1 course for the treatment of (60 days courses for the treatment of), most long 4 courses for the treatment of, average 3 courses for the treatment of.320 are cured, accounts for 53%；Effective 240
Example, accounts for 40%；Invalid 40, account for 7%.Total effective rate is 93%.
(2), using Domperidone as control, the activity gels (treatment group) and fourth of protection, renovating tummy mucous membrane to gained
Quinoline (control group) contrasts the result for the treatment of functional dyspepsia FD (amounting to 180), and the results are shown in Table 1 for it.
The effect of 1 integrative therapy functional dyspepsia FD of table (example)
Note：* compared with the control group, P ＜ 0.05.
As can be seen from Table 1, treatment group compared with control group to the therapeutic effect of the sufferer of functional dyspepsia FD more preferably, and have
There is notable difference.Illustrate the protection for the treatment of group, the activity gels of renovating tummy mucous membrane compared with Western medicine Domperidone to functional dyspepsia FD
Sufferer therapeutic effect it is significantly superior.
(3), using positive intestines raw rubber capsule as control, the activity gels (treatment group) of protection, renovating tummy mucous membrane to gained and
Positive intestines raw rubber capsule (control group) contrasts the result for the treatment of irritable bowel syndrome (amounting to 190), its result such as institute of table 2
Show.
The effect of 2 integrative therapy irritable bowel syndrome of table (example)
Note：* compared with the control group, P ＜ 0.05.
As can be seen from Table 2, treatment group compared with control group to the therapeutic effect of the sufferer of irritable bowel syndrome more preferably, and have
There is notable difference.It is comprehensive to illustrate that the protection for the treatment of group, the activity gels of renovating tummy mucous membrane easily swash enteron aisle compared with the positive intestines raw rubber capsule of Western medicine
The therapeutic effect for closing the sufferer of disease is significantly superior.
In conclusion the protection of the embodiment of the present invention, the activity gels abundant raw material of renovating tummy mucous membrane and proportioning are proper, no
Comprehensive raising gastrointestinal function is only capable of, increases it and intestines and stomach noxious substance is acted on, cuticula sore, and to oral cavity, food
The various inflammation and mucosa injury in road, stomach and intestines have good treatment and repair, moreover it is possible to improve biological utilisation
Spend, reduction dose, saving Chinese medicaments resource, reduce the toxic side effect of Chinese medicine.Its preparation method is simple, pharmaceutical activity reserving degree
It is high.
Embodiments described above is part of the embodiment of the present invention, instead of all the embodiments.The reality of the present invention
The detailed description for applying example is not intended to limit the scope of claimed invention, but is merely representative of the selected implementation of the present invention
Example.Based on the embodiments of the present invention, those of ordinary skill in the art are obtained without creative efforts
Every other embodiment, belongs to the scope of protection of the invention.
Claims (10)
1. a kind of protection, the activity gels of renovating tummy mucous membrane, it is characterised in that its raw material includes bletilla, the 2-6 of 2-6 parts by weight
The cornu cerve degelatinatum of parts by weight, the garden burnet skin of 2-6 parts by weight, the Sculellaria barbata of 2-6 parts by weight, the rhizoma nelumbinis of 2-6 parts by weight, 1-5 parts by weight
Radix Paeoniae Alba, the Rhizoma Atractylodis Macrocephalae of 1-5 parts by weight, the pseudo-ginseng of 1-5 parts by weight, the Chinese yam of 1-5 parts by weight, 0.5-4 parts by weight raddle,
The betel nut of 0.5-4 parts by weight, the hairyvein agrimony of 0.5-4 parts by weight, the pearl of the pueraria lobata of 0.5-4 parts by weight and 0.2-2 parts by weight.
2. activity gels according to claim 1, it is characterised in that its raw material includes the bletilla, the 3- of 3-5 parts by weight
The cornu cerve degelatinatum of 5 parts by weight, the garden burnet skin of 3-5 parts by weight, the Sculellaria barbata of 3-5 parts by weight, the institute of 3-5 parts by weight
State rhizoma nelumbinis, the Radix Paeoniae Alba of 2-4 parts by weight, the Rhizoma Atractylodis Macrocephalae of 2-4 parts by weight, the pseudo-ginseng of 2-4 parts by weight, 2-4 parts by weight
The Chinese yam, the raddle of 1.5-3 parts by weight, the betel nut of 1.5-3 parts by weight, the celestial being of 1.5-3 parts by weight
Crane is careless, the pearl of pueraria lobata and the 0.8-1.2 parts by weight of 1.5-3 parts by weight.
3. activity gels according to claim 2, it is characterised in that its raw material includes the bletilla, 4 weights of 4 parts by weight
Measure the cornu cerve degelatinatum of part, the garden burnet skin of 4 parts by weight, the Sculellaria barbata of 4 parts by weight, the rhizoma nelumbinis of 4 parts by weight, 3
The Radix Paeoniae Alba of parts by weight, the Rhizoma Atractylodis Macrocephalae of 3 parts by weight, the pseudo-ginseng of 3 parts by weight, the Chinese yam of 3 parts by weight, 2 weight
The raddle, the betel nut of 2 parts by weight, the hairyvein agrimony of 2 parts by weight, the pueraria lobata and 1 weight of 2 parts by weight of part
Measure the pearl of part.
4. such as the preparation method of claim 1-3 any one of them activity gels, it is characterised in that comprise the following steps：Will
The cornu cerve degelatinatum, the garden burnet skin, the Sculellaria barbata, the rhizoma nelumbinis, the Radix Paeoniae Alba, the Rhizoma Atractylodis Macrocephalae, the pseudo-ginseng, the mountain
Medicine, the raddle, the betel nut, the hairyvein agrimony, the pueraria lobata and the pearl are pulverized, and extract bletilla glue, mixing
The powder particle of gained, steams and shines after the bletilla glue and grinding, disinfection.
5. activity gels according to claim 4, it is characterised in that the bletilla glue obtains in the following manner：By institute
State bletilla and at least 48h is extracted in water, leaching liquor is mixed at least 24h with alcohol, filter, collect sediment；
Preferably, the alcohol includes ethanol.
6. activity gels according to claim 5, it is characterised in that extraction includes the first leaching stages and the second extraction rank
Section, the first leaching stages are that 10-15h is extracted under conditions of 10-30 DEG C, and the second leaching stages are under conditions of 50-60 DEG C
Extract at least 38h.
7. activity gels according to claim 5, it is characterised in that the volume ratio of the alcohol and leaching liquor is 10-20：4-
6。
8. activity gels according to claim 7, it is characterised in that the alcohol contains ethanol, propyl alcohol and propane diols, described
The mass percent of ethanol described in alcohol is 40-50wt%；
Preferably, the volume ratio of the ethanol, the propyl alcohol and the propane diols is 40-50：10-20：20-25.
9. activity gels according to claim 4, it is characterised in that the granularity of the powder particle of gained is after grinding
65-100 mesh；
Preferably, at least containing 3 kinds of different granularities in the powder particle.
10. activity gels according to claim 4, it is characterised in that disinfection is carried out under the conditions of existing for Co 60.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810033402.XA CN107929550A (en) | 2018-01-12 | 2018-01-12 | It is a kind of protect, the activity gels of renovating tummy mucous membrane and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810033402.XA CN107929550A (en) | 2018-01-12 | 2018-01-12 | It is a kind of protect, the activity gels of renovating tummy mucous membrane and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107929550A true CN107929550A (en) | 2018-04-20 |
Family
ID=61938650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810033402.XA Pending CN107929550A (en) | 2018-01-12 | 2018-01-12 | It is a kind of protect, the activity gels of renovating tummy mucous membrane and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107929550A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101032333A (en) * | 2007-04-11 | 2007-09-12 | 朱西杰 | Herbal meal of gastrointestinal sustained release particle for protecting gastrointestinal mucosa |
| CN102125660A (en) * | 2010-12-24 | 2011-07-20 | 朱西杰 | Traditional Chinese medicine sustained-release micro granules stomach and intestine partner for protecting and strengthening functions of stomach and intestine |
-
2018
- 2018-01-12 CN CN201810033402.XA patent/CN107929550A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101032333A (en) * | 2007-04-11 | 2007-09-12 | 朱西杰 | Herbal meal of gastrointestinal sustained release particle for protecting gastrointestinal mucosa |
| CN102125660A (en) * | 2010-12-24 | 2011-07-20 | 朱西杰 | Traditional Chinese medicine sustained-release micro granules stomach and intestine partner for protecting and strengthening functions of stomach and intestine |
Non-Patent Citations (5)
| Title |
|---|
| 安婷婷等: "慢性萎缩性胃炎胃黏膜修复方法临床研究", 《山东中医杂志》 * |
| 朱西杰等: "中药护膜剂微观辨治胃病", 《湖北中医学院学报》 * |
| 梁岩等: ""护胃膜药糊"对胃粘膜损伤修复的临床观察", 《宁夏医学杂志》 * |
| 苏维霞等: "朱西杰治疗慢性萎缩性胃炎的思路与方法", 《辽宁中医药大学学报》 * |
| 谢崇义等: "白及胶提取工艺的优选", 《安徽医药》 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101066445A (en) | Chinese medicine prepn for curing gastropathy radically | |
| CN108524814A (en) | A kind of Chinese medicine composition and preparation method thereof for reducing blood glucose | |
| CN101297889B (en) | Chinese medicine preparation for treating foot-and-mouth disease and preparation method thereof | |
| CN109350718A (en) | Clearing damp Chinese medicine composition and preparation method thereof | |
| CN101554362A (en) | Composition of natural product and preparation thereof | |
| CN104873826A (en) | Tea drink capable of clearing away lung heat and dispelling damp and preparation method thereof | |
| CN100488540C (en) | Anti-obesity ingredients from medicinal plants and their composition | |
| CN102688384B (en) | Traditional Chinese medicine decoction for treating chronic pharyngitis | |
| CN104547961B (en) | A kind of Chinese medicine composition for treating gall stone | |
| CN106692909A (en) | Pyrus pyrifolia tree viscum coloratum grease with lung-clearing and phlegm-eliminating effects | |
| CN107929550A (en) | It is a kind of protect, the activity gels of renovating tummy mucous membrane and preparation method thereof | |
| CN102988747B (en) | Aristida triseta electuary for reducing hypertension, hyperglycemia and hyperlipidemia and preparation method thereof | |
| CN105664053A (en) | Traditional Chinese medicine composition for treating calluses on puncture of internal arteriovenous fistula of maintenance hemodialysis patient | |
| CN111437378A (en) | Traditional Chinese medicine composition and medicine for preventing and treating chronic heart failure and preparation method thereof | |
| CN110917249A (en) | Traditional Chinese medicine composition for prostate and preparation method and application thereof | |
| CN115252732B (en) | Traditional Chinese medicine composition for clearing lung and relieving cough and application thereof | |
| CN103340991A (en) | Oral liquid for nursing diabetics and preparation method thereof | |
| CN100490874C (en) | Chinese medicine composition for treating diabetes and method for preparing the same | |
| CN1895503A (en) | Hairy antler capsules | |
| CN108853380B (en) | Pharmaceutical composition for treating diabetes and preparation method and application thereof | |
| CN105250903A (en) | Traditional Chinese medicine physiotherapeutic liquid for treating numbness of limbs and preparation method of traditional Chinese medicine physiotherapeutic liquid | |
| CN105942227A (en) | Roe deer meat medicinal diet suitable for body slimming and skin whitening of patients with diabetes and preparation method thereof | |
| CN105267745A (en) | Traditional Chinese medicine composition for treating uremia and preparation method | |
| CN104435950A (en) | Traditional Chinese medicinal styptic powder for treating upper gastrointestinal hemorrhage and preparation method thereof | |
| CN104623248A (en) | Drug for clearing heat and removing dampness for patient with chronic enteritis and preparation method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180420 |