CN107920501A - 基于干细胞的器官和组织的产生的方法 - Google Patents
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
- C07K16/3092—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated mucins
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
- A01K2267/025—Animal producing cells or organs for transplantation
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| US201562187638P | 2015-07-01 | 2015-07-01 | |
| US62/187,638 | 2015-07-01 | ||
| US201562234035P | 2015-09-29 | 2015-09-29 | |
| US62/234,035 | 2015-09-29 | ||
| PCT/US2016/040880 WO2017004601A1 (en) | 2015-07-01 | 2016-07-01 | Method of stem cell-based organ and tissue generation |
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| CN107920501A true CN107920501A (zh) | 2018-04-17 |
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| WO2021263227A2 (en) | 2020-06-26 | 2021-12-30 | Minerva Biotechnologies Corporation | Anti-nme antibody and method of treating cancer or cancer metastasis |
| KR20250009592A (ko) | 2022-04-12 | 2025-01-17 | 미네르바 바이오테크놀로지 코포레이션 | 항-가변 muc1* 항체 및 그의 용도 |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102397115A (zh) * | 2011-07-10 | 2012-04-04 | 黄必录 | 避免器官移植排斥的方案 |
| US20120156246A1 (en) * | 2010-06-16 | 2012-06-21 | Bamdad Cynthia C | Reprogramming cancer cells |
| WO2014012115A2 (en) * | 2012-07-13 | 2014-01-16 | Minerva Biotechnologies Corporation | Method for inducing cells to less mature state |
| WO2014119627A1 (ja) * | 2013-01-29 | 2014-08-07 | 国立大学法人 東京大学 | キメラ動物の作製方法 |
| CN103998598A (zh) * | 2011-10-17 | 2014-08-20 | 米纳瓦生物技术公司 | 用于干细胞增殖和诱导的培养基 |
| US20150089677A1 (en) * | 2013-02-20 | 2015-03-26 | Minerva Biotechnologies Corporation | Method for enhancing tumor growth |
-
2016
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- 2016-07-01 CA CA2991125A patent/CA2991125A1/en not_active Abandoned
- 2016-07-01 EP EP16818944.7A patent/EP3316682A4/en not_active Withdrawn
- 2016-07-01 US US15/740,654 patent/US20180235193A1/en not_active Abandoned
- 2016-07-01 KR KR1020187003027A patent/KR20180032583A/ko not_active Ceased
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- 2016-07-01 KR KR1020217011287A patent/KR20210045513A/ko not_active Ceased
- 2016-07-01 WO PCT/US2016/040880 patent/WO2017004601A1/en not_active Ceased
- 2016-07-01 JP JP2018500321A patent/JP2018520682A/ja active Pending
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2017
- 2017-12-25 IL IL256549A patent/IL256549A/en unknown
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120156246A1 (en) * | 2010-06-16 | 2012-06-21 | Bamdad Cynthia C | Reprogramming cancer cells |
| CN102397115A (zh) * | 2011-07-10 | 2012-04-04 | 黄必录 | 避免器官移植排斥的方案 |
| CN103998598A (zh) * | 2011-10-17 | 2014-08-20 | 米纳瓦生物技术公司 | 用于干细胞增殖和诱导的培养基 |
| WO2014012115A2 (en) * | 2012-07-13 | 2014-01-16 | Minerva Biotechnologies Corporation | Method for inducing cells to less mature state |
| WO2014119627A1 (ja) * | 2013-01-29 | 2014-08-07 | 国立大学法人 東京大学 | キメラ動物の作製方法 |
| US20150089677A1 (en) * | 2013-02-20 | 2015-03-26 | Minerva Biotechnologies Corporation | Method for enhancing tumor growth |
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| SANJEEV MAHANTA ET AL.: ""A Minimal Fragment of MUC1 Mediates Growth of Cancer Cells"", 《PLOS ONE》 * |
| TAMIR RASHID ET AL.: ""Revisiting the Flight of Icarus: Making Human Organs from PSCs with Large Animal Chimeras"", 《CELL STEM CELL》 * |
| 陈庆峰 等: ""鼠-人嵌合抗粘蛋白1 IgG1全抗体的构建及其功能初步分析"", 《第三军医大学学报》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2016287603A1 (en) | 2018-01-25 |
| US20180235193A1 (en) | 2018-08-23 |
| JP2018520682A (ja) | 2018-08-02 |
| WO2017004601A1 (en) | 2017-01-05 |
| KR20210045513A (ko) | 2021-04-26 |
| EP3316682A1 (en) | 2018-05-09 |
| IL256549A (en) | 2018-02-28 |
| EP3316682A4 (en) | 2019-01-23 |
| KR20180032583A (ko) | 2018-03-30 |
| CA2991125A1 (en) | 2017-01-05 |
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