CN107898939A - A kind of composition with prevention and treatment infantile eczema - Google Patents
A kind of composition with prevention and treatment infantile eczema Download PDFInfo
- Publication number
- CN107898939A CN107898939A CN201711077053.3A CN201711077053A CN107898939A CN 107898939 A CN107898939 A CN 107898939A CN 201711077053 A CN201711077053 A CN 201711077053A CN 107898939 A CN107898939 A CN 107898939A
- Authority
- CN
- China
- Prior art keywords
- composition
- prevention
- infantile eczema
- treatment infantile
- oat
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/733—Fructosans, e.g. inulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
Abstract
The invention discloses a kind of composition with prevention and treatment infantile eczema, it is characterised in that containing active ingredient prebiotics, olive extract, oat extract and ceramide, the percentage by weight of each active ingredient in the composition is：Prebiotics：0.01~20.00wt%, olive extract：0.01~50.00wt%；Oat extract：0.01~10.00wt%；Ceramide：0.01~10.00wt%；The present invention can effectively remove eczema from prevention, treatment, the solution for repairing three dimensions offer eczema.
Description
Technical field
The present invention relates to medicine or skin care field, more particularly to a kind of combination with prevention and treatment infantile eczema
Thing.
Background technology
Infantile eczema is commonly called as infantile eczema, is the allergic skin inflammation as caused by a variety of internal causes and external cause, skin generally occurs
Skin is rubescent, oedema, itch, drying, crusts, infiltration, the symptom such as bleeding even occurs.The treatment of infantile eczema is generally using drink
The means such as oesophagus reason, drug therapy and the external application of Chinese medicine.Contain hormone etc. in the topical agent of some treatment infantile eczemas at present
Baby uses with caution and has the component of side effect.Chinese medicinal external application treatment eczema is configured using some clearing heat and detoxicating Chinese herbal medicines,
These technological means carry out eczema treatment by antiallergy, anti-inflammatory, reparation, such as number of patent application 201710122001.7, patent
Application number 2016112406080.X, number of patent application 201510215082.6 have the therapeutic scheme of eczema.But existing technology
Means are primarily present following deficiency：1st, long-time service is larger there are side effect；2nd, enhancing infant skin resists the skill of environmental stimuli
Art means deficiency is inadequate in the function of eczema caused by prevention external cause.
The content of the invention
In view of the deficiencies of the prior art, the present invention provides a kind of composition with prevention and treatment infantile eczema.
In order to reach above-mentioned technique effect, the technical solution adopted by the present invention is：
A kind of composition with prevention and treatment infantile eczema, it is characterised in that the effective active components of said composition
For prebiotics, olive extract, oat extract and ceramide, the percentage by weight of each active ingredient in the composition
For：
(a) prebiotics：0.01~20.00wt%；
(b) olive extract：0.01~50.00wt%；
(c) oat extract：0.01~10.00wt%；
(d) ceramide：0.01~10.00wt%；
Preferably, the prebiotics include inulin, oligofructose, xylo-oligosaccharide, oligomeric lactose, galactooligosaccharide and α-
One or more in glucan oligosaccharides.
Preferably, the prebiotics includes inulin, oligofructose, oligomeric lactose, galactooligosaccharide and alpha-glucans widow
One or more in sugar.
Preferably, the prebiotics includes inulin, oligofructose, oligomeric lactose and alpha-glucans oligosaccharides.
Preferably, the polyphenol content of the olive extract is more than 2%.
Preferably, the polyphenol content of the olive extract is more than 10%, wherein hydroxytyrosol content is more than 2%.
Preferably, the verbascoside in the olive extract is more than 1%.
Preferably, the content of oat acyl group ortho-aminobenzoic acid is more than 10ppm in the oat extract.
Preferably, the content of oat acyl group ortho-aminobenzoic acid is more than 50ppm in the oat extract.
Preferably, the content of oat acyl group ortho-aminobenzoic acid is not less than 100ppm in the oat extract.
Preferably, the ceramide includes Cer NS, Cer NP, Cer AP, class ceramide, plant
One or more in thing sphingol, glycosyl sphingolipid and digalactosyl diglycerol fat.
Preferably, the ceramide includes Cer NP, phytosphingosine, glycosyl sphingolipid and digalactosyl diglycerol
One or more in fat.
Preferably, the ceramide includes Cer NP, glycosyl sphingolipid and digalactosyl diglycerol fat.
Compared with prior art, the beneficial effects of the invention are as follows：
1st, eczema can effectively be removed from prevention, treatment, the solution for repairing three dimensions offer eczema；
2nd, prebiotics, ceramide strengthen bacterium colony barrier, the physical barriers of infant skin, and enhancing skin resists environmental stimuli
Ability；
3rd, olive extract, oat extract from antibacterial, anti-inflammatory, anti-oxidant angle to eczema it is red, swell, the symptom such as itch into
Row treatment and reparation.
4th, the present composition is free of antibiotic, hormone, has no toxic side effect, and long-time service contains the product of this composition,
Can alleviate various discomforts caused by infantile eczema immediately, long-time service, which can strengthen skin, which resists the external world, stress and influence, repair by
Skin is damaged, prevents the generation of eczema.
Embodiment
The present invention is described in further details with reference to specific embodiment：
It is of the invention that a kind of composition with prevention and treatment infantile eczema is provided, particular by beneficial using active ingredient
Raw member, olive extract, oat extract and ceramide, and above-mentioned four classes active ingredient is dissolved into according to a certain percentage and is added
Enter and be formulated in the solvent of additive, there is prevention, treatment, repair infantile eczema, it can apply but be not limited to baby
Child personal care product.Said composition each component weight proportion is：
(a) prebiotics content is 0.01~20.00wt%；
(b) 0.01~50.00wt% of olive extract content；
(c) 0.01~10.00wt% of oat extract content；
(d) 0.01~10.00wt% of ceramide content；
(e) remaining is solvent and additive.
Wherein, composition prebiotics includes but not limited to inulin, oligofructose, xylo-oligosaccharide, oligomeric lactose, oligomeric gala
One or more in sugar and alpha-glucans oligosaccharides；Wherein be preferably inulin, oligofructose, oligomeric lactose, galactooligosaccharide and
One or more in alpha-glucans oligosaccharides；More preferably inulin, oligofructose, oligomeric lactose and alpha-glucans oligosaccharides.
Wherein, the polyphenol content of olive extract is more than 2% in composition；It is preferred that polyphenol content is more than 6%；It is more preferably more
Phenol content is more than 10%, and wherein hydroxytyrosol is more than content 2%；More preferably polyphenol content is more than 10%, and wherein hydroxytyrosol is big
In 2%, verbascoside is more than 1%.
Wherein, oat extract contains more than 10ppm oat acyl group ortho-aminobenzoic acids in composition, preferably comprises and is more than
50ppm oat acyl group ortho-aminobenzoic acids, further preferably not less than 100ppm oat acyl group ortho-aminobenzoic acids.
Wherein, ceramide is neural including but not limited to Cer NS, Cer NP, Cer AP, class in composition
One or more in acid amides, phytosphingosine, glycosyl sphingolipid and digalactosyl double glyceride, are preferably Cer NP, plant sheath
One or more in ammonia alcohol, glycosyl sphingolipid and digalactosyl double glyceride, more preferably Cer NP, glycosyl sphingolipid and two galas
Sugared double glyceride.
Wherein, solvent can be water, polyalcohol (such as glycerine, propane diols etc.) in composition, and additive is lived for some surfaces
Property agent, include but not limited to polyoxyethylene (20) sorbitanmonolaureate, lauryl glucoside.
The present invention is free of antibiotic, hormone, has no toxic side effect, and can be suitable for infant, pass through prebiotics, ceramide
Strengthen bacterium colony barrier, the physical barriers of infant skin, enhancing skin resists the ability of environmental stimuli；Meanwhile extracted by olive
Thing, oat extract from antibacterial, anti-inflammatory, anti-oxidant angle to eczema it is red, swell, the symptom such as itch is treated and repaired.For a long time
Using various discomforts caused by infantile eczema can be alleviated immediately, while it can also strengthen skin and resist the external world and stress and influence, repair
Damaged skin, prevents the generation of eczema.
The present invention is not limited to above-mentioned specific embodiment, for those of ordinary skill in the art from above-mentioned structure
Think of sets out, and without performing creative labour, made a variety of conversion, are within the scope of the present invention.
Claims (13)
1. a kind of composition with prevention and treatment infantile eczema, it is characterised in that the effective active components of said composition are
Prebiotics, olive extract, oat extract and ceramide, the percentage by weight of each active ingredient in the composition are：
(a) prebiotics：0.01~20.00wt%；
(b) olive extract：0.01~50.00wt%；
(c) oat extract：0.01~10.00wt%；
(d) ceramide：0.01~10.00wt%.
2. the composition of prevention and treatment infantile eczema according to claim 1, it is characterised in that the prebiotics includes
One or more in inulin, oligofructose, xylo-oligosaccharide, oligomeric lactose, galactooligosaccharide and alpha-glucans oligosaccharides.
3. the composition of prevention and treatment infantile eczema according to claim 2, it is characterised in that the prebiotics includes
One or more in inulin, oligofructose, oligomeric lactose, galactooligosaccharide and alpha-glucans oligosaccharides.
4. the composition of prevention and treatment infantile eczema according to claim 3, it is characterised in that the prebiotics includes
Inulin, oligofructose, oligomeric lactose and alpha-glucans oligosaccharides.
5. the composition of prevention and treatment infantile eczema according to claim 1, it is characterised in that the olive extract
Polyphenol content be more than 2%.
6. the composition of prevention and treatment infantile eczema according to claim 5, it is characterised in that the olive extract
Polyphenol content be more than 10%, wherein hydroxytyrosol content be more than 2%.
7. the composition of prevention and treatment infantile eczema according to claim 6, it is characterised in that the olive extract
In verbascoside be more than 1%.
8. the composition of prevention and treatment infantile eczema according to claim 1, it is characterised in that the oat extract
The content of middle oat acyl group ortho-aminobenzoic acid is more than 10ppm.
9. the composition of prevention and treatment infantile eczema according to claim 8, it is characterised in that the oat extract
The content of middle oat acyl group ortho-aminobenzoic acid is more than 50ppm.
10. the composition of prevention and treatment infantile eczema according to claim 9, it is characterised in that the oat extraction
The content of oat acyl group ortho-aminobenzoic acid is not less than 100ppm in thing.
11. the composition of prevention and treatment infantile eczema according to claim 1, it is characterised in that the ceramide
It is double sweet including Cer NS, Cer NP, Cer AP, class ceramide, phytosphingosine, glycosyl sphingolipid and digalactosyl
One or more in grease.
12. the composition of prevention and treatment infantile eczema according to claim 11, it is characterised in that the ceramide
Including the one or more in Cer NP, phytosphingosine, glycosyl sphingolipid and digalactosyl diglycerol fat.
13. the composition of prevention and treatment infantile eczema according to claim 12, it is characterised in that the ceramide
Including Cer NP, glycosyl sphingolipid and digalactosyl diglycerol fat.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711077053.3A CN107898939A (en) | 2017-11-06 | 2017-11-06 | A kind of composition with prevention and treatment infantile eczema |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711077053.3A CN107898939A (en) | 2017-11-06 | 2017-11-06 | A kind of composition with prevention and treatment infantile eczema |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107898939A true CN107898939A (en) | 2018-04-13 |
Family
ID=61843519
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711077053.3A Pending CN107898939A (en) | 2017-11-06 | 2017-11-06 | A kind of composition with prevention and treatment infantile eczema |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107898939A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019236935A1 (en) * | 2018-06-08 | 2019-12-12 | The Procter & Gamble Company | Topical skincare compositions comprising centella asiatica selected triterpenes |
| CN112245347A (en) * | 2020-10-09 | 2021-01-22 | 名臣健康用品股份有限公司 | Hip-protecting composition for preventing and treating diaper rash and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101287480A (en) * | 2005-08-31 | 2008-10-15 | 强生消费者公司 | Anti-inflammatory compositions and methods of use |
| CN105997593A (en) * | 2016-07-04 | 2016-10-12 | 广东添乐化妆品有限公司 | Prebiotic function formula for adjusting unbalance of skin bacterial flora and relieving eczema |
| CN107126405A (en) * | 2017-05-05 | 2017-09-05 | 小牛哞哞母婴用品(深圳)有限公司 | It is a kind of to aim at protection children sebum film, the skin care item containing milk extract |
-
2017
- 2017-11-06 CN CN201711077053.3A patent/CN107898939A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101287480A (en) * | 2005-08-31 | 2008-10-15 | 强生消费者公司 | Anti-inflammatory compositions and methods of use |
| CN105997593A (en) * | 2016-07-04 | 2016-10-12 | 广东添乐化妆品有限公司 | Prebiotic function formula for adjusting unbalance of skin bacterial flora and relieving eczema |
| CN107126405A (en) * | 2017-05-05 | 2017-09-05 | 小牛哞哞母婴用品(深圳)有限公司 | It is a kind of to aim at protection children sebum film, the skin care item containing milk extract |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019236935A1 (en) * | 2018-06-08 | 2019-12-12 | The Procter & Gamble Company | Topical skincare compositions comprising centella asiatica selected triterpenes |
| US10980851B2 (en) | 2018-06-08 | 2021-04-20 | The Procter & Gamble Company | Topical skincare compositions comprising Centella asiatica selected triterpenes |
| CN112245347A (en) * | 2020-10-09 | 2021-01-22 | 名臣健康用品股份有限公司 | Hip-protecting composition for preventing and treating diaper rash and preparation method thereof |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180413 |
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| RJ01 | Rejection of invention patent application after publication |