CN107898850A - A kind of pharmaceutical composition for phlegm-dampness constitution - Google Patents
A kind of pharmaceutical composition for phlegm-dampness constitution Download PDFInfo
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- CN107898850A CN107898850A CN201711227182.6A CN201711227182A CN107898850A CN 107898850 A CN107898850 A CN 107898850A CN 201711227182 A CN201711227182 A CN 201711227182A CN 107898850 A CN107898850 A CN 107898850A
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- pharmaceutical composition
- phlegm
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/346—Platycodon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a kind of pharmaceutical composition, it is made of the bulk pharmaceutical chemicals of following weight proportion：4~10 parts of semen brassicae, 4~10 parts of radish seed, 4~10 parts of perilla seed, 1~5 part of campanulaceae, 1~5 part of dried orange peel, 1~5 part of emblic.Preparation method present invention also offers described pharmaceutical composition and its purposes in the medicine for improving phlegm-dampness constitution is prepared.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition for phlegm-dampness constitution.
Background technology
Phlegm-dampness constitution is one of nine kinds of common biased constitutions, and it is main that it is greasy etc., which to stick tongue, with body obesity, belly grossness, mouth
Feature.
Phlegm-dampness constitution is high blood pressure, cerebrovas-cularaccident, coronary heart disease, diabetes, metabolic syndrome, polycystic ovary synthesis
Sign, sleep apnea syndrome etc. are a variety of with the pathogenesis basis of phlegm wet relevant disease.Its tendency of falling ill seriously endangers human body and is good for
Health, should be prevented early.
But the medicine still lacked at present to the ill is used for the improvement and treatment of phlegm-dampness constitution crowd.Therefore, there is an urgent need for one group by medicine
Eat the composition of homologous Chinese medicine composition, serial symptom caused by energy effectively preventing phlegm-dampness constitution, and safe without toxic side effect.
The content of the invention
It is an object of the invention to provide a kind of pharmaceutical composition for phlegm-dampness constitution.
Another object of the present invention is to provide the preparation method and purposes of the composition.
The present invention provides a kind of pharmaceutical composition, it is prepared by the bulk pharmaceutical chemicals of following weight proportion：Semen brassicae 4
~10 parts, 4~10 parts of radish seed, 4~10 parts of perilla seed, 1~5 part of campanulaceae, 1~5 part of dried orange peel, 1~5 part of emblic.
Preferably, it is prepared by the bulk pharmaceutical chemicals of following weight proportion：6 parts of semen brassicae, 6 parts of radish seed, perilla seed 6
Part, 3 parts of campanulaceae, 3 parts of dried orange peel, 3 parts of emblic.
Wherein, foregoing pharmaceutical composition be with semen brassicae, radish seed, perilla seed, campanulaceae, dried orange peel, emblic crude drug,
Water extract either extractive with organic solvent prepared for active ingredient plus pharmaceutically acceptable auxiliary material or complementary component and
Into preparation.
Wherein, the preparation is oral formulations.
Further, the oral formulations are decoction, electuary, pill, tablet, powder, granule, sublimed preparation or oral liquid.
The present invention provides a kind of method for preparing aforementioned pharmaceutical compositions, include the following steps：
A) bulk pharmaceutical chemicals of each weight proportion are weighed；
B) raw material directly beaten to powder, or after adding water or organic solvent extraction, add pharmaceutically acceptable auxiliary material or auxiliary
Property component is prepared.
Present invention also offers purposes of the foregoing pharmaceutical composition in the medicine for improving phlegm-dampness constitution is prepared.
Foregoing pharmaceutical composition sticks the greasy medicine of tongue in body obesity, belly grossness or mouth caused by preparation treatment phlegm-dampness constitution
Purposes in thing.
Pharmaceutical composition of the present invention is by semen brassicae, radish seed, perilla seed, campanulaceae, dried orange peel, emblic six medicaments group
Into.
Semen brassicae is warm-natured in side, acrid flavour, there is the effect of moistening lung for removing phlegm, swelling and pain relieving；Radish seed is mild-natured, acrid flavour, sweet, helps digestion
De-swelling, lowering the adverse-rising QI to resolve phlegm；Perilla seed is warm-natured, acrid flavour, has sending down abnormally ascending dissolving phlegm, relieving cough and asthma, purging and intestine lubricating action；Campanulaceae is mild-natured, bitter,
It is pungent, facilitaing lung, relieving sore-throat, eliminating the phlegm, apocenosis；Dried orange peel is warm-natured, and acrid flavour, hardship, regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm；Emblic is cool in nature, sweet in flavor, sour,
It is puckery, there is clearing heat and cooling blood, food digesting stomach fortifying, cough-relieving effect of promoting the production of body fluid.
Semen brassicae is warming lung and reducing phlegm in side, qi-regulating dissipating bind；Perillaseed droping gas resolving sputum, it is relieving cough and asthma；Radish seed promoting digestion, lower gas
Eliminating the phlegm.Assistant is with campanulaceae relieving sore-throat eliminating the phlegm, dried orange peel regulating qi-flowing for strengthening spleen, emblic food digesting stomach fortifying, so that the internal organs caused by adjusting phlegm-dampness constitution
Qi-blood-body fluid transporting, water are wet to stop gathering, accumulates in phlegm wet.
Pharmaceutical composition of the present invention is evident in efficacy to phlegm-dampness constitution patient, and toxic side effect is small, and preparation process is simple, user
Just, there is preferable potential applicability in clinical practice.
The above according to the present invention, according to the ordinary technical knowledge and customary means of relevant art, not
Under the premise of departing from the above-mentioned basic fundamental thought of the present invention, the modification, replacement or change of other diversified forms can also be made.
The embodiment of form by the following examples, remakes further specifically the above of the present invention
It is bright.But the scope that this should not be interpreted as to the above-mentioned theme of the present invention is only limitted to following example.It is all to be based on the above of the present invention
The technology realized belongs to the scope of the present invention.
Embodiment
The preparation of 1 pharmaceutical composition of the present invention of embodiment
1. raw material：Semen brassicae 6g, radish seed 6g, perilla seed 6g, campanulaceae 3g, dried orange peel 3g, emblic 3g.
2. preparation method：Bulk pharmaceutical chemicals are weighed by above-mentioned weight proportion；Smash to pieces slightly, add a certain amount of water, be put into pot
Decoct, keep slightly boiling 10~15 minutes, you can.
The preparation of 2 pharmaceutical composition of the present invention of embodiment
1. raw material：Semen brassicae 4g, radish seed 10g, perilla seed 4g, campanulaceae 5g, dried orange peel 1g, emblic 5g.
2. preparation method：Bulk pharmaceutical chemicals are weighed by above-mentioned weight proportion；Smash to pieces slightly, add a certain amount of water, be put into pot
Decoct, keep slightly boiling 10~15 minutes, you can.
The preparation of 3 pharmaceutical composition of the present invention of embodiment
1. raw material：Semen brassicae 10g, radish seed 4g, perilla seed 10g, campanulaceae 1g, dried orange peel 5g, emblic 1g.
2. preparation method：Bulk pharmaceutical chemicals are weighed by above-mentioned weight proportion；Smash to pieces slightly, add a certain amount of water, be put into pot
Decoct, keep slightly boiling 10~15 minutes, you can.
Beneficial effects of the present invention are proved below by way of specific clinical test：
Test example 1：The clinical efficacy of the present composition
1st, clinical data
This clinical test is carried out in the volunteer that intra-company recruits, and is meeting clinical test《Medicine Ethics》Will
Ask down, according in March, 2009 China Association of Traditional Chinese Medicine's issue《Traditional Chinese Medicine Constitution Classification is with judging》The tcm constitution of standard formulation
Recognize scale and carry out tcm constitution identification, screening phlegm-dampness constitution volunteer 49.Wherein man 31, female 18.
1.1 diagnostic criteria：
With reference to China Association of Traditional Chinese Medicine's issue《Traditional Chinese Medicine Constitution Classification is with judging》Standard screening, clinical diagnosis mainly show
For perspire it is more stick greasy, the wet hidrosis of brothers' tidal surge of emotion, often feels that limbs are aching and tired heavy, and face often has greasy feeling, often has glue in the mouth
Or sweet sensation, usually abundant expectoration etc..
1.2 inclusive criteria
The case for meeting 1.1 section diagnostic criteria is included.
2nd, treatment method
Experimental group：Give the medicine of the embodiment of the present invention 1.
Usage：Each bulk pharmaceutical chemicals are weighed according to prescription ratio, are smashed to pieces slightly, a certain amount of water is added, is put into pot and decocts, are protected
Hold slightly boiling 10~15 minutes.Make tea-drinking, daily 1 dose.Continuously take 1 month.
3rd, observation of curative effect
3.1 criterion of therapeutical effect：
It is clearly better：Clinical symptoms, sign disappear substantially；
Improve：Clinical symptoms, sign improve；
It is invalid：Clinical symptoms, sign nothing are substantially change.
3.2 treatment results
As shown in table 1：
Comparison of therapeutic after table 1 is taken medicine
| Group | Number of cases | It is clearly better | Improve | It is invalid | Total effective rate % |
| Treatment group | 49 | 17 | 29 | 3 | 94% |
Experiment conclusion：According to statistical result after medication, phlegm can effectively be alleviated and treat by taking the present composition
Wet caused range of clinical performance.It is definite that this patent is directed to the effect of phlegm-dampness constitution, is worth clinical application.
4th, model case
4.1 classical cases 1
Dragon certain, man is 57 years old, fat, feels that shortness of breath uncomfortable in chest is had palpitation for a long time, there is hypertension, sleepy, the thick greasy fur of body weight,
Aggravated during feed sweetness greasy food, through Chinese medical discrimination category phlegm-dampness constitution.
Take the present composition to have improved for 1 month, continue to take 2 months, symptom is alleviated substantially.
4.2 classical cases 2
Liao, man, 35 years old, chest and abdomen discomfort due to fullness, fat abdomen fertilizer, drowsiness, tongue body fat big, tongue sticked greasy, abundant expectoration in vain, hidrosis and
Glutinous, stool is sticky, urine is yellowish, through Chinese medical discrimination category phlegm-dampness constitution.
Take the present composition 2 months, remission, constitution returns to normal.
4.3 classical cases 3
Lee, man, 41 years old, the bodily form was fat, belly grossness and soft, four limbs edema, by depression, do not feel like eating, body is weary
Lazy move, uncomfortable in chest, nausea, through Chinese medical discrimination category phlegm-dampness constitution.
Take the present composition 2 months, remission, continues after taking 2 months, constitution returns to normal.
4.4 classical cases 4
Cai, female is 32 years old, nose heave feeling dazed, nausea uncomfortable in chest, and good tired contracting, One's hands and feet were icy cold, uncomfortable in chest, abundant expectoration, easily feels sleepy, few dynamic
Sitting, tongue is fat, and tongue is greasy, through Chinese medical discrimination category phlegm-dampness constitution.
To sum up, pharmaceutical composition of the present invention is evident in efficacy to phlegm-dampness constitution patient, and toxic side effect is small, and preparation process is simple,
It is easy to use, there is preferable potential applicability in clinical practice.
Claims (8)
- A kind of 1. pharmaceutical composition, it is characterised in that：It is prepared by the bulk pharmaceutical chemicals of following weight proportion：Semen brassicae 4~ 10 parts, 4~10 parts of radish seed, 4~10 parts of perilla seed, 1~5 part of campanulaceae, 1~5 part of dried orange peel, 1~5 part of emblic.
- 2. pharmaceutical composition according to claim 1, it is characterised in that：It is by following weight proportion bulk pharmaceutical chemicals prepare and Into：6 parts of semen brassicae, 6 parts of radish seed, 6 parts of perilla seed, 3 parts of campanulaceae, 3 parts of dried orange peel, 3 parts of emblic.
- 3. pharmaceutical composition according to claim 1 or claim 2, it is characterised in that：It is with semen brassicae, radish seed, perilla seed, tangerine Stalk, dried orange peel, the crude drug of emblic, water extract or extractive with organic solvent are active ingredient, plus pharmaceutically acceptable Preparation is prepared in auxiliary material or complementary component.
- 4. pharmaceutical composition according to claim 3, it is characterised in that：The preparation is oral formulations.
- 5. pharmaceutical composition according to claim 4, it is characterised in that：The oral formulations are decoction, electuary, pill, piece Agent, powder, granule, sublimed preparation or oral liquid.
- A kind of 6. method for preparing claim 1-5 any one described pharmaceutical compositions, it is characterised in that：Including following step Suddenly：A) bulk pharmaceutical chemicals of each weight proportion are weighed；B) raw material directly beaten to powder, or after adding water or organic solvent extraction, add pharmaceutically acceptable auxiliary material or it is complementary into Divide and be prepared.
- 7. purposes of the claim 1-5 any one described pharmaceutical composition in the medicine for improving phlegm-dampness constitution is prepared.
- 8. claim 1-5 any one described pharmaceutical composition is preparing body obesity, belly caused by treatment phlegm-dampness constitution Grossness or mouth stick the purposes in the greasy medicine of tongue.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711227182.6A CN107898850A (en) | 2017-11-29 | 2017-11-29 | A kind of pharmaceutical composition for phlegm-dampness constitution |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711227182.6A CN107898850A (en) | 2017-11-29 | 2017-11-29 | A kind of pharmaceutical composition for phlegm-dampness constitution |
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| Publication Number | Publication Date |
|---|---|
| CN107898850A true CN107898850A (en) | 2018-04-13 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711227182.6A Pending CN107898850A (en) | 2017-11-29 | 2017-11-29 | A kind of pharmaceutical composition for phlegm-dampness constitution |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102302721A (en) * | 2011-09-16 | 2012-01-04 | 成都中医药大学 | Pharmaceutical composition for treating bronchitis as well as preparation method and use thereof |
| WO2014123305A2 (en) * | 2013-02-08 | 2014-08-14 | 주식회사 파미니티 | Composition for preventing, improving or treating male climacteric containing dandelion extract or composite extract containing dandelion as active ingredient |
-
2017
- 2017-11-29 CN CN201711227182.6A patent/CN107898850A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102302721A (en) * | 2011-09-16 | 2012-01-04 | 成都中医药大学 | Pharmaceutical composition for treating bronchitis as well as preparation method and use thereof |
| WO2014123305A2 (en) * | 2013-02-08 | 2014-08-14 | 주식회사 파미니티 | Composition for preventing, improving or treating male climacteric containing dandelion extract or composite extract containing dandelion as active ingredient |
Non-Patent Citations (1)
| Title |
|---|
| WWW.ZHMF5.COM: ""治疗一切怪病药方（三子养亲汤：莱菔子 白芥子 苏子）"", 《HTTP://WWW.ZHMF5.COM/MIFANGDAQUAN/BAOJIAN/2016-06-21/12903.HTML》 * |
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Application publication date: 20180413 |
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