CN107890444A - A kind of extracting method of plant society extract and the personal care composition for alleviating inflammation - Google Patents
A kind of extracting method of plant society extract and the personal care composition for alleviating inflammation Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/596—Mixtures of surface active compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/82—Preparation or application process involves sonication or ultrasonication
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- Medicines Containing Plant Substances (AREA)
Abstract
The present invention relates to technical field of natural product extraction, further relates to a kind of personal care composition.A kind of plant society extract extracting method, it is that glycyrrhiza glabra, radix scutellariae, Flos Chrysanthemi extract through ultrasonic wave extraction, the extraction efficiency of active ingredient is higher in extract, being capable of Synergistic between extract, after tested, the content of most of non-beneficial bacterium on skin can be reduced, and does not have too many reduction for the content of beneficial bacterium.A kind of personal care composition for alleviating inflammation, contains plant society extract, anion surfactant, amphoteric surfactant, APG, the NMF, and pure water.The personal care composition causes product to be reduced for the influence that skin lipid is reset, and can adjust microbial environment, reduces the checking respective degrees of product, and can alleviate skin checking.Composition composition is gentle, and the skin that all kinds of skins are even produced with inflammation is applicable, significant effect, and application is simple and direct.
Description
Technical field
The present invention relates to technical field of natural product extraction, further relates to a kind of personal care composition.
Background technology
In the skin of consumer perceivable and the ill symptomses of scalp, itch, shouting pain, dry and cracked etc. it is bad feel to account for
Principal element, and there are several factors to cause this sensation, wherein extraneous factor is more important factor, extraneous bad ring
Border can stimulate human skin to produce inflammation.Meanwhile with present scientific and technological progressively development, it is believed that inflammation would is that master
The main reason for causing human body surface inferior health problem.Although problem also has the reason for individual life habit, or even individual
The reason on gene, but it is same very important in these extraneous poor environments.
Surfactant in still further aspect, detergent has the influence reset, this influence to the lipid of skin
If continue the long time, or degree is higher, it would be possible to the inflammatory response of skin can be caused, meanwhile, if skin parasitism has
The microorganisms such as some microorganism chlosmas, it would be possible to obvious inflammatory response is produced, and some microorganisms are in skin
Upper not much influences, have positive role, such as MRSE, it is impossible to go out without exception to health on the contrary.Therefore,
Rearrangement of the detergent to skin lipid is reduced, and the microbial environment problem of skin will be adjusted, it will is shower cream for reality
Now alleviate one of inflammation function technological difficulties to be solved.
For present product in order to realize good antiphlogistic effects, majority can be with allantoin, dipotassium glycyrrhizinate, hexamidine dihydroxy
Ethyl sulfonate etc. antibacterial anti-inflammatory agent, although collocation has been considered to the effect with synergy two-by-two, it is still not able to
Microbial environment is adjusted to reasonable direction, angle of the inventor in exploration from plant extract for this, and the angle of formulation optimization,
Low, the good product of microbial environment regulating effect of negative effect is reset to design a lipid.
The content of the invention
It is an object of the invention to overcome, to reset skin lipid serious for shower cream product in the prior art, and can not have
A kind of technological deficiency of selective control microbial environment, there is provided extracting method of plant society extract.
It is a further object of the present invention to provide a kind of shower cream matrix so that product drops for the influence that skin lipid is reset
It is low, and microbial environment can be adjusted, the checking respective degrees of product are reduced, and skin checking can be alleviated.Composition
Composition is gentle, and the skin that all kinds of skins are even produced with inflammation is applicable, significant effect, and application is simple and direct.
The technical scheme that the present invention reaches above-mentioned purpose is：
A kind of personal care composition of the alleviation inflammation of extract containing plant society, the personal care composition contains following heavy
Measure the raw material of percentage proportioning：
（A）Glycyrrhiza glabra, radix scutellariae, Flos Chrysanthemi combined extracts 1-10%；
（B）Anion surfactant 5-20%；
（C）Amphoteric surfactant 0.3-30%；
（D）APG 0.5-3.0%；
（E）NMF 0.05-35%；The NMF is by glycerine 5-30%, pyrrolidone sodium carboxylate 0.05 ~ 10%, trimethylammonium second
Lactone 0.05 ~ 2%；Aloe extract 0.01-5% is formed；
And surplus
（G）Pure water.
Described plant society extract is extracted by following methods：
（1）Glycyrrhiza glabra, radix scutellariae, Flos Chrysanthemi are pressed into 30-40：20-30：30-50 mass ratio crushes, and 30 ~ 40 DEG C of dryings, powder
Broken and dried mixed-powder is input in extraction tube by quantitative feeding device by the charging aperture of ultrasonic extractor, while will be carried
Take solvent（Concentration is 65% ~ 85% ethanol solution）It is heated to 60-80 DEG C and extraction tube is input to by the deslagging end of ultrasonic extractor
It is interior, solid-liquid ratio 1：4~1：12；
（2）Plant society powder and Extraction solvent are subjected to adverse current ultrasound at normal temperatures and pressures in the extraction tube of ultrasonic extractor
20-50 minutes are extracted, frequency setting is 20 ~ 40kHz；
（3）After completing ultrasonic extraction, material residue is discharged by the slag-drip opening of ultrasonic extractor, carried by the leakage fluid dram discharge of ultrasonic extractor
Take liquid；
（4）Plant society extract is obtained after extract solution vacuum drying.
Described anion surfactant is selected from ethoxylated dodecyl alcohol sulfate, glycerine monofatty ester sulfuric acid
Salt, fatty alcohol ether sulfosuccinate ester salt, N- fatty acyl amino-acid salts, fatty acyl methyl tauride, monoalkyl sulfate are single
Alkyl carboxylate, the one or more in alkylphosphonate.Wherein preferably at least contain N- fatty acyl amino-acid salts, fat
One or both of acyl methyl taurine salt, is found through experiments that, containing such as amino acid surfactant structure, and
Surfactant with larger Packing parameter, help to reduce integral system excitant.
Described amphoteric surfactant is selected from fatty acyl both sexes acetate, fatty acyl CAB, fatty acid amide hydroxyl
One or more in propylsultaine glycine betaine.Preferred fat acyl both sexes acetate and one kind in fatty acyl CAB or
Two kinds, particularly preferred fatty acyl CAB.With the addition of amphoteric surfactant, micellar conformation changes, monomer
Anion surfactant reduce, so as to reduce the influence that surfactant is reset to lipid；
Described APG is synthesized by renewable resource natural fat alcohol and glucose, the carbon chain lengths of natural fatty alcohol
Selected from C6-C18Carbochain is distributed, preferably C8-C12Carbochain distribution.Preferable carbochain distribution has is distributed milder than other carbochains
Excitant and the compatibility to human body, injury of the surfactant for skin can be reduced.
It is 0.05-35% that described NMF, which accounts for total composition, by glycerine 5-30%, pyrrolidone sodium carboxylate 0.05 ~
10%, betaine 0.05 ~ 2%, aloe extract 0.01-1% compositions.It is applicant's understanding that only optimizing surface activating agent
The degree negatively affected for skin reduction reached of arranging in pairs or groups simultaneously is insufficient to, and is tested through applicant and is found there are being a large amount of moisturizings
Under the presence effect of agent, skin can show obvious beneficial effect, wherein just including the inflammatory response of skin surface, especially
It is that the scytitis reduced caused by surfactant is reset to skin lipid responds, and gain of the NMF for skin is made
With, with NMF disclosed by the invention combination be more highly preferred to.
The personal care composition of the above-mentioned alleviation inflammation containing plant society extract, except above-mentioned necessary composition
Outside, the also at least one containing following component：
Suspending agent：0.01-5%；
Organic conditioning oil：0.01-2%
Higher aliphatic：0.01-5%
Preservative：0.01-1%；
Essence：0.01-3%；
Viscosity modifier：0.01-4%；
Chelating agent：0.005-0.2%；
Ultra-violet absorber：0.01-2%；
Other plant extracts and its derivative：0.0001-5%；
It is above-mentioned containing glycyrrhiza glabra, radix scutellariae, german chamomile flower extract alleviation inflammation personal care composition, can arbitrary proportion with often
It is made with base-material in shower class cosmetics, State of cosmetics can be one in solution, suspension, emulsion, paste, solid-like
Kind.
It is above-mentioned it is a kind of containing glycyrrhiza glabra, radix scutellariae, german chamomile flower extract alleviation inflammation personal care composition, its configure
Method is conventional configuration and hybrid technology, is not elaborated herein.
The present invention has the advantages that：
（1）After glycyrrhiza glabra, radix scutellariae, Flos Chrysanthemi extract through ultrasonic wave extraction, the extraction effect of active ingredient in extract
Rate is higher, between extract can Synergistic, after tested, the content of most of non-beneficial bacterium can be reduced on skin, and for
The content of beneficial bacterium does not have too many reduction；
（2）As the matrix of shower cream, the collocation of surfactant can reduce the influence reset to lipid on skin.In addition,
NMF application collocation can unexpected generation beneficial effect, can not only further reduce monomer table work to skin
Influence, additionally it is possible to which, to the helpful effect of skin, this is a kind of and surfactant framework Synergistic result；
（3）Plant society extract, surfactant framework and NMF three mutually assist a ruler in governing a country and are mutually improved, can be from different angles
Degree has gain effect to skin.
Therefore, the present invention can reduce rearrangement of the detergent to skin lipid, and the microbial environment that will adjust skin
Problem, it can alleviate inflammation so as to reach, further benefit skin, deficiency of the prior art can be promoted.
Embodiment
With reference to embodiment, the present invention will be described in detail.
Wherein, the plant society extract of embodiment and comparative example be glycyrrhiza glabra, radix scutellariae, Flos Chrysanthemi combined extracts, by with
Lower method extraction：
（1）Glycyrrhiza glabra, radix scutellariae, Flos Chrysanthemi are pressed 30： 30：After 40 mass ratio crushes, and 35 DEG C dry, pulverize and dry
Mixed-powder be input to by quantitative feeding device by the charging aperture of ultrasonic extractor in extraction tube, while by Extraction solvent（It is dense
Spend the ethanol solution for 75%）It is heated to 70 DEG C to be input in extraction tube by the deslagging end of ultrasonic extractor, solid-liquid ratio 1：10；
（2）Plant society powder and Extraction solvent are subjected to adverse current ultrasound at normal temperatures and pressures in the extraction tube of ultrasonic extractor
Extraction 30 minutes, frequency setting 30kHz；
（3）After completing ultrasonic extraction, material residue is discharged by the slag-drip opening of ultrasonic extractor, carried by the leakage fluid dram discharge of ultrasonic extractor
Take liquid；
（4）Plant society extract is obtained after extract solution vacuum drying.
The experiment of inhibition zone size is disclosed a kind of experimental method in the industry, is not described in detail here, and inhibition zone size is weighing apparatus
Measure the important indicator strong and weak to the strain rejection ability, inhibition zone size is bigger, and to represent bacteriostasis stronger.Above test result
As can be seen that plant society extract can cause the strain of scytitis to have stronger bacteriostasis to chlosma etc., and
It is weak for the bacteriostasis of epidermis grape ball, it preferably can retain beneficial bacterium and reduce the amount of depending on of chlosma.
Surfactant residual quantity is to weigh the important indicator that surfactant is reset to skin lipid, tests table
Bright, plant society extract disclosed by the invention can reduce surfactant residual quantity, but main reduction surfactant is residual
The combination of still NMF and the collocation of surfactant of allowance.
Claims (7)
1. a kind of extracting method of plant society extract, it is characterised in that extracting method is：
S1, glycyrrhiza glabra, radix scutellariae, Flos Chrysanthemi pressed into 30-40：20-30：30-50 mass ratio crushes, and 30 ~ 40 DEG C of dryings, powder
Broken and dried mixed-powder is input in extraction tube by quantitative feeding device by the charging aperture of ultrasonic extractor, while will be carried
Take solvent to be heated to 60-80 DEG C to be input in extraction tube by the deslagging end of ultrasonic extractor, solid-liquid ratio 1：4~1：12；
S2, mixed-powder and Extraction solvent be subjected to adverse current ultrasonic extraction at normal temperatures and pressures in the extraction tube of ultrasonic extractor
20-50 minutes, frequency setting are 20 ~ 40kHz；
S3, after completing ultrasonic extraction, material residue is discharged by the slag-drip opening of ultrasonic extractor, carried by the leakage fluid dram discharge of ultrasonic extractor
Take liquid；
Plant society extract is obtained after S4, extract solution vacuum drying.
2. extracting method according to claim 1, it is characterised in that：Described Extraction solvent is that concentration is 65% ~ 85%
Ethanol solution.
A kind of 3. personal care composition for alleviating inflammation, it is characterised in that the component containing following mass percent：
（A）Plant society extract 1-10% described in claim 1 or 2；
（B）Anion surfactant 5-20%；
（C）Amphoteric surfactant 0.3-30%；
（D）APG 0.5-3.0%；
（E）NMF 0.05-35%；The NMF is by glycerine 5-30%, pyrrolidone sodium carboxylate 0.05 ~ 10%, trimethylammonium second
Lactone 0.05 ~ 2%；Aloe extract 0.01-5% is formed；
And surplus
（G）Pure water.
4. the personal care composition according to claim 3 for alleviating inflammation, it is characterised in that：Described anionic surface
Activating agent is selected from ethoxylated dodecyl alcohol sulfate, glycerine monofatty ester sulfate, fatty alcohol ether sulfosuccinic acid
Ester salt, N- fatty acyl amino-acid salts, fatty acyl methyl tauride, monoalkyl sulfate, monoalkyl carboxylate, single alkyl phosphonic acid
At least one of ester salt.
5. the personal care composition according to claim 3 for alleviating inflammation, it is characterised in that：Described amphoteric surface lives
Property agent in fatty acyl both sexes acetate, fatty acyl CAB, fatty acid amide hydroxypropyl sulfobetaines at least one
Kind.
6. the personal care composition according to claim 3 for alleviating inflammation, it is characterised in that：Described APG is
Synthesized by renewable resource natural fat alcohol and glucose, the carbon chain lengths of natural fatty alcohol are distributed selected from C6-C18 carbochains.
7. the personal care composition according to claim 3 for alleviating inflammation, it is characterised in that：Also containing following component
It is at least one：
Suspending agent：0.01-5%；
Organic conditioning oil：0.01-2%
Higher aliphatic：0.01-5%
Preservative：0.01-1%；
Essence：0.01-3%；
Viscosity modifier：0.01-4%；
Chelating agent：0.005-0.2%；
Ultra-violet absorber：0.01-2%；
Other plant extracts and its derivative：0.0001-5%.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711127012.0A CN107890444B (en) | 2017-11-15 | 2017-11-15 | Extraction method of plant combined extract and personal care composition for relieving inflammation |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711127012.0A CN107890444B (en) | 2017-11-15 | 2017-11-15 | Extraction method of plant combined extract and personal care composition for relieving inflammation |
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| CN107890444A true CN107890444A (en) | 2018-04-10 |
| CN107890444B CN107890444B (en) | 2021-04-27 |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104274371A (en) * | 2014-09-30 | 2015-01-14 | 澳宝化妆品（惠州）有限公司 | Method for extracting lupulus and application of extracting solution of lupulus |
| CN106333881A (en) * | 2016-10-26 | 2017-01-18 | 澳宝化妆品（惠州）有限公司 | Moistening, bubbly and stable cream bath combination |
-
2017
- 2017-11-15 CN CN201711127012.0A patent/CN107890444B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104274371A (en) * | 2014-09-30 | 2015-01-14 | 澳宝化妆品（惠州）有限公司 | Method for extracting lupulus and application of extracting solution of lupulus |
| CN106333881A (en) * | 2016-10-26 | 2017-01-18 | 澳宝化妆品（惠州）有限公司 | Moistening, bubbly and stable cream bath combination |
Non-Patent Citations (3)
| Title |
|---|
| 夏秋香等: ""药用植物母菊的成分和功能研究进展"", 《园艺学报》 * |
| 李宏: ""黄芩的生物活性及其在化妆品中的应用"", 《香料香精化妆品》 * |
| 罗祖良等: ""光果甘草的研究进展"", 《中草药》 * |
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Address after: 516000 Licheng industrial area, Shuikou Town, Huicheng District, Huizhou, Guangdong, China Applicant after: Huizhou Zhaoting Cosmetic Co., Ltd. Address before: 516000 Licheng industrial area, Shuikou Town, Huicheng District, Huizhou, Guangdong, China Applicant before: Huizhou Zhao Qi Gift Co. Ltd. |
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