CN107875363A - 一种用于治疗月经先期的药物 - Google Patents

一种用于治疗月经先期的药物 Download PDF

Info

Publication number
CN107875363A
CN107875363A CN201711158420.2A CN201711158420A CN107875363A CN 107875363 A CN107875363 A CN 107875363A CN 201711158420 A CN201711158420 A CN 201711158420A CN 107875363 A CN107875363 A CN 107875363A
Authority
CN
China
Prior art keywords
parts
medicine
treat
radix
rhizome
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201711158420.2A
Other languages
English (en)
Inventor
王克荣
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201711158420.2A priority Critical patent/CN107875363A/zh
Publication of CN107875363A publication Critical patent/CN107875363A/zh
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/39Convolvulaceae (Morning-glory family), e.g. bindweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/43Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/89Cyperaceae (Sedge family)
    • A61K36/8905Cyperus (flatsedge)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994Coix (Job's tears)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

本发明属于中药组合物技术领域,具体涉及一种用于治疗月经先期的药物。其由以下组分组成:香附子、当归、白芍、白术、丹参、桂枝、肉桂、生姜、山药、茯苓、薏苡仁、栀子、杜仲、枸杞、黄芪、茵陈、菟丝子、杏仁、甘草;用本发明的药物治疗月经先期,治疗效果好,治愈率高,复发率低。

Description

一种用于治疗月经先期的药物
技术领域
本发明属于中药组合物技术领域,具体涉及一种用于治疗月经先期的药物。
背景技术
月经先期为月经周期提前7天以上,或20天左右一行,连续发生2个周期或以上,月经先期多为湿热(血热)气血不足,常伴有心急,气短,乏力。
发明内容
本发明的目的是针对现有技术存在的问题提供一种用于治疗月经先期的药物。
本发明的具体技术方案如下:
一种用于治疗月经先期的药物,由以下重量份数的组分组成:香附子8-10份,当归10-15份,白芍10-15份,白术10-20份,丹参8-12份,桂枝8-10份,肉桂4-6份,生姜1-3份,山药10-20份茯苓10-30份,薏苡仁10-30份,栀子8-10份,杜仲10-15份,枸杞8-15份黄芪10-20份,茵陈10-20份,菟丝子8-10份,杏仁8-10份,甘草8-10份。
本发明各组分药理如下:
当归:甘、辛、温;归肝、心、脾经;补血活血止痛;
薏苡仁:甘、淡、微寒;归脾、胃肺经;利水渗湿,健脾;
丹参:苦、微寒;归心肝、经;活血去瘀,凉血止痛;
白术:苦、甘、温;归脾、胃经;补气健脾,燥湿利水;
甘草:甘、平;归心、肺、脾、胃经;补脾益气,清热解毒,调和诸药;
桂枝:辛、甘、温;归心、肺、膀胱经;助阳解表,温通血脉;
肉桂:辛、甘、温;归心、肺、膀胱经;助阳解表,温通血脉,温中散寒;
香附子:辛、苦、微寒;归肝、三焦经;疏肝理气止疼;
白芍:苦、酸、微寒;归肝、脾经;养血敛阴,柔肝止疼,和营血;
栀子:苦、寒;归心、肺、胃、三焦经;清热利湿,降三焦之火;
茯苓:甘、淡、平;归心、脾、肾经;利水渗湿,健脾;
杏仁:苦、温;归肺、大肠;止咳平喘;
茵陈:苦、微寒;归脾、胃、肝、胆经;清热利湿;
山药:甘、平;归脾、胃、肾经;益气养阴,补益肝肾;
黄芪:甘、温;归脾、肺经;升阳补气,益卫固表;
菟丝子:辛、甘、平;归肝、肾、脾经;补阳益阴,固精缩尿;
杜仲:甘、温;归肝、肾经;补益肝肾,强筋骨;
枸杞:甘、平;归肝、肾、肺经;滋补肝肾;
生姜:辛、微温;归肺、脾胃经;发汗解表,温胃止呕,散寒止咳,除湿开胃。
本发明具有以下有意效果:
本发明的药物中:菟丝子,枸杞,杜仲,山药补益肝肾。当归,丹参,白芍,补血活血调经止痛,香附子活血行气止痛,桂枝,肉桂,生姜温中散寒止痛,薏苡仁,茵陈,栀子清热利湿。白术,杏仁,茯苓,甘草,健脾益气,通利水湿。黄芪补脾益气;采用本发明的药物治疗月经先期,治疗效果好,治愈率高,复发率低。
具体实施方式
下面结合实施例对本发明作进一步说明。
实施例1
一种用于治疗月经先期的药物,由以下重量份数的组分组成:桂枝8份,肉桂4份,生姜1份,山药10份,茯苓10份,薏苡仁10份,栀子8份,杜仲10份,黄芪10份,茵陈10份,菟丝子8份,杏仁8份,甘草8份。
使用时在上述中药组合物中加水500ml,煎至200ml,纱布过滤去渣,放置药液温凉至35-45℃,口服。
实施例2
一种用于治疗月经先期的药物,由以下重量份数的组分组成:桂枝10份,肉桂6份,生姜3份,山药20份,茯苓30份,薏苡仁30份,栀子10份,杜仲15份,枸杞15份,黄芪20份,茵陈20份,菟丝子10份,杏仁10份,甘草10份。
使用时在上述中药组合物中加水500ml,煎至200ml,纱布过滤去渣,放置药液温凉至35-45℃,口服。
临床试验:
1.1一般资料
100例月经先期患者中,年龄20-40岁,患者临床表现:月经周期提前7天以上,或20天左右一行,连续发生2个周期或以上,伴有心急,气短,乏力;随机分为治疗组和对照组,每组50例,两组年龄、临床情况等比较差异无统计学意义(P>0.05),具有可比性。
1.2治疗方法
1.2.1对照组给予常规治疗月经先期药物口服。
1.2.2治疗组给予本发明实施例1中药组合物制得的药液口服,每次月经期间服药。
1.2.3疗程三个月经期。
1.3观察指标
治疗前后记录患者临床症状的改善情况。
1.4疗效评定标准
显效:症状消失或基本消失,或由较重减到轻度;
有效:发作次数明显减少、程度明显减轻、持续时间明显减少;
无效:症状与治疗前基本相同;
加重:发作次数增加、程度加重,持续时间更长。
1.5统计学方法 采用SPSS13.0统计软件进行统计分析,计量资料采用均数±标准差(`x±s)表示,采用t检验;计数资料采用x2检验。
1.6结果
两组患者临床症状疗效比较治疗组总有效率远远高于对照组,差异有统计学意义(P<0.05)(见表1)

Claims (1)

1.一种用于治疗月经先期的药物,其特征在于,由以下重量份数的组分组成:香附子8-10份,当归10-15份,白芍10-15份,白术10-20份,丹参8-12份,桂枝8-10份,肉桂4-6份,生姜1-3份,山药10-20份,茯苓10-30份,薏苡仁10-30份,栀子8-10份,杜仲10-15份,枸杞8-15份,黄芪10-20份,茵陈10-20份,菟丝子8-10份,杏仁8-10份,甘草8-10份。
CN201711158420.2A 2017-11-20 2017-11-20 一种用于治疗月经先期的药物 Withdrawn CN107875363A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711158420.2A CN107875363A (zh) 2017-11-20 2017-11-20 一种用于治疗月经先期的药物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711158420.2A CN107875363A (zh) 2017-11-20 2017-11-20 一种用于治疗月经先期的药物

Publications (1)

Publication Number Publication Date
CN107875363A true CN107875363A (zh) 2018-04-06

Family

ID=61777560

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201711158420.2A Withdrawn CN107875363A (zh) 2017-11-20 2017-11-20 一种用于治疗月经先期的药物

Country Status (1)

Country Link
CN (1) CN107875363A (zh)

Similar Documents

Publication Publication Date Title
CN102512630B (zh) 一种治疗胆囊结石的中药组合物
CN103536858A (zh) 一种治疗类风湿性关节炎的药物
CN103585401A (zh) 一种治疗禽流感的中药组合物及其制备方法
CN111671864A (zh) 一种减轻化疗引起的骨髓抑制的中药制剂及其制备方法
CN104352939A (zh) 一种治疗消化性溃疡及抗幽门螺杆菌的胶囊
CN101112518A (zh) 一种治疗产后血虚发热的中药制剂
CN104667035A (zh) 一种治疗痛风的药物
CN103041271B (zh) 一种治疗肺气肿的中药组合物
CN107875363A (zh) 一种用于治疗月经先期的药物
CN109908245A (zh) 一种用于治疗颈肩腰腿痛病的中药组合物
CN103463463A (zh) 一种补血活血、祛风除湿的中药制剂
CN107184906A (zh) 用于治疗痛经的中药组合物及其制备方法
CN102940770A (zh) 一种急性炎症性脱髓鞘性多发性神经病的中药
CN103007238B (zh) 一种治疗褥疮的中药组合物
CN105998738A (zh) 一种治疗盗汗的中药组合物
CN106177561A (zh) 一种治疗肺结核的中药组合物
CN105853580A (zh) 治疗顽固性水肿的中药组合物
CN104800355A (zh) 一种治疗肝硬化的中药
CN104888182A (zh) 一种治疗产后腹痛的中药制剂及其制备方法
CN104758888A (zh) 一种治疗消渴病的中药组合物
CN104398961A (zh) 一种治疗病毒性肝炎的中药制剂
CN104257833A (zh) 一种治疗痛风的中药组合物
CN115919989A (zh) 用于骨科围手术期气虚血瘀患者的中药组合物及制备方法
CN114652797A (zh) 用于骨折患者养血补气的中药配方及其中药液的制备方法
CN103028104B (zh) 一种治疗腹痛的中药组合物

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication
WW01 Invention patent application withdrawn after publication

Application publication date: 20180406