CN107874743A - One kind record conscious mouse respiratory movement and habituation are with removing habituation device - Google Patents
One kind record conscious mouse respiratory movement and habituation are with removing habituation device Download PDFInfo
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- CN107874743A CN107874743A CN201711248424.XA CN201711248424A CN107874743A CN 107874743 A CN107874743 A CN 107874743A CN 201711248424 A CN201711248424 A CN 201711248424A CN 107874743 A CN107874743 A CN 107874743A
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- 206010052804 Drug tolerance Diseases 0.000 title claims abstract description 51
- 230000026781 habituation Effects 0.000 title claims abstract description 51
- 230000033001 locomotion Effects 0.000 title claims abstract description 51
- 230000000241 respiratory effect Effects 0.000 title claims abstract description 21
- 230000029058 respiratory gaseous exchange Effects 0.000 claims abstract description 54
- 238000012549 training Methods 0.000 claims abstract description 24
- 238000001514 detection method Methods 0.000 claims abstract description 13
- 238000000034 method Methods 0.000 claims abstract description 11
- 238000012806 monitoring device Methods 0.000 claims abstract description 11
- 238000012544 monitoring process Methods 0.000 claims abstract description 10
- 230000000638 stimulation Effects 0.000 claims abstract description 9
- 230000008569 process Effects 0.000 claims abstract description 7
- 238000012545 processing Methods 0.000 claims abstract description 7
- 230000003321 amplification Effects 0.000 claims description 8
- 210000003928 nasal cavity Anatomy 0.000 claims description 8
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 8
- 230000000694 effects Effects 0.000 claims description 7
- 230000008859 change Effects 0.000 claims description 6
- 238000003780 insertion Methods 0.000 claims description 6
- 230000037431 insertion Effects 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 5
- 230000035479 physiological effects, processes and functions Effects 0.000 claims description 4
- 238000007789 sealing Methods 0.000 claims description 4
- 230000009471 action Effects 0.000 claims description 3
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- 238000002474 experimental method Methods 0.000 abstract description 9
- 241001465754 Metazoa Species 0.000 abstract description 5
- 230000002349 favourable effect Effects 0.000 abstract description 3
- 230000036387 respiratory rate Effects 0.000 description 5
- 238000010586 diagram Methods 0.000 description 3
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- 238000013456 study Methods 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 206010002091 Anaesthesia Diseases 0.000 description 1
- 208000010392 Bone Fractures Diseases 0.000 description 1
- 241001062472 Stokellia anisodon Species 0.000 description 1
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- 230000001070 adhesive effect Effects 0.000 description 1
- 230000037005 anaesthesia Effects 0.000 description 1
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- 229960005475 antiinfective agent Drugs 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000035565 breathing frequency Effects 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2503/00—Evaluating a particular growth phase or type of persons or animals
- A61B2503/40—Animals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2503/00—Evaluating a particular growth phase or type of persons or animals
- A61B2503/42—Evaluating a particular growth phase or type of persons or animals for laboratory research
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- Heart & Thoracic Surgery (AREA)
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- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
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Abstract
The present invention relates to one kind record conscious mouse respiratory movement and habituation and remove habituation device, it is characterised in that：It includes being used to detect mouse breathing situation and generates the breathing tape deck of corresponding event signal, for monitoring mouse movement situation and generating the movement locus monitoring device of corresponding motor message, for monitor mouse to Odor stimulation or habituation with go habituation training mission and generate corresponding detection signal to device of air, for receiving the micro controller of event signal, motor message and detection signal analyzing and processing；For showing the display of each data, described display is connected to micro controller.Whole experiment process of the present invention is full-automation, only needs to start shooting in experiment and is put into mouse and connects connecting line, and other are all automatically performed by animal and the device；The device can accurate recording mouse in habituation and the breathing gone during habituation and movement locus signal, so as to provide favourable scientific basis during detected by scent for breathing.
Description
Technical field
The present invention relates to one kind record conscious mouse respiratory movement and habituation and remove habituation device.
Background technology
The detected by scent process of humans and animals be required for by constantly periodically air-breathing come obtain and update the external world
Matter information is smelt, therefore perception of the respiratory to olfactory information is most important, this also makes many smell researchers pay close attention to always to exhale
Inhale the effect during detected by scent.A large amount of correlative studys in recent years are related to people and rat, and it is various types of other
Animal, particularly compared with toy such as mouse research get up relative difficulty；And the experiment of traditional record animal breath motion is more
Measured using trachea cannula pneumography, recorder method (physiograph method) and using movement of thorax, this kind of side
Method is although simple and easy, but have damage, take time and effort, accuracy it is inadequate；And at present respiratory movement for mouse habituation with
Role is still unclear during going habituation, does not also have accurate effective method by conscious mouse respiratory movement and habit
Usedization is with going the device of habituation to combine.
The content of the invention
For described above, it is an object of the invention to provide one kind record conscious mouse respiratory movement and habituation with going
Habituation device, with least one aspect that solves the above problems.
Technical scheme is used by order to realize the purpose of the present invention：One kind record conscious mouse respiratory movement and custom
Change and remove habituation device, it is characterised in that：It includes being used to detect mouse breathing situation and generates exhaling for corresponding event signal
Tape deck is inhaled, for monitoring mouse movement situation and generating the movement locus monitoring device of corresponding motor message, for monitoring
Mouse to Odor stimulation or habituation with go habituation training mission and generate corresponding detection signal to device of air, for receiving
The micro controller of event signal, motor message and detection signal analyzing and processing；For showing the display of each data, described is aobvious
Show that device is connected to micro controller；
Described breathing tape deck, movement locus monitoring device and the output end to device of air respectively connected micro controller
Input, event signal, motor message and detection signal are analyzed and processed by micro controller, finally mouse exhaled
The physiology and appearance of suction, smell and motion is monitored in real time.
Further, described breathing tape deck includes breathing sleeve pipe, small hose, baroceptor and amplifier；It is described
Breathing sleeve pipe be made up of conduit and conduit cap, conduit cap sleeve is connected on conduit, one end of its conduit insertion mouse suitable position
Nasal cavity in, the other end is connected to that sealing is good, is adapted to the small hose of diameter.
Further, described baroceptor is caused soft intraductal atmospheric pressure in the expiration of detection mouse and breathing process
Change and generate breathing induced signal, the baroceptor described in it is located in small hose, and the output end of baroceptor connects
Then amplifier.
Further, described amplifier is the breathing induced signal amplification that will be recorded, and the input of amplifier is connected to
Baroceptor, output end are connected to micro controller, so as to which the breathing induced signal after amplification is sent into micro controller, micro controller pair
Induced signal is sent to display and shown after being handled.
Further, described movement locus monitoring device include be used for monitor and record mouse movement track camera and
Pole, described camera are located at the top that can monitor mouse movement track, and camera is connected to micro controller, so as to be gathered
To motor message be sent to micro controller, micro controller is shown to being sent to after motor message processing on display；Described
Pole is used for fixing camera.
Further, it is described to include training place and multi-channel gas generation device to device of air.
Further, described training place be mouse in certain spacious space can free activity place.
Further, described multi-channel gas generation device is by gas pipeline, flowmeter, magnetic valve, odor bottle, air pressure
Contracting pump, relay and infrared tube composition；Described gas pipeline one end connection odor bottle, other end connection training place；It is described
Odor bottle inside be provided with a certain proportion of odor liquids；Described air pressure pump connection odor bottle, passes through air pressure pump
Give odor bottle certain air pressure, by the control of flowmeter, so as to which the smell in odor bottle be transported to by gas pipeline
Training place so that mouse sucks smell and realizes the stimulation of smell.
Further, described magnetic valve is connected in connecting tube, and its magnetic valve is connected to relay；Described relay is defeated
Enter end and be connected to micro controller.
Further, described flowmeter is located on gas pipeline, and the output end of flowmeter is connected to micro controller.
Further, described infrared tube is located at the side of gas pipeline gas outlet in training place, its infrared tube it is defeated
Go out end and be connected to micro controller, described infrared tube can monitor that mouse exploration goes the action signal of smelling the moment, and will
The information transmission is to micro controller.
Further, data acquisition module is provided with described micro controller, so that by data acquisition module to each data
It is acquired and preserves.
Further, be provided with can be with the amplifier, camera, relay, flowmeter and infrared for described micro controller
The communication control interface compatible to pipe.
Beneficial effects of the present invention：
1st, whole experiment process is full-automation, only needs to start shooting in experiment and is put into mouse and connects connecting line i.e.
Can, other are all automatically performed by animal and the device.
2nd, the device can accurate recording mouse in habituation and the breathing gone during habituation and movement locus signal,
So as to provide favourable scientific basis during detected by scent for breathing；
3rd, the device can accurate recording mouse in habituation and the breathing gone during habituation and movement locus signal,
So as to provide favourable scientific basis during detected by scent for breathing；Simultaneously and evaluation relevant nerve diseases treatment is new
The powerful of medicine；
4th, the breathing tape deck is simple to operate, and the damage to mouse is small, convenient and easy, very big to realize mouse and instructing
Practice the freely activity in place；
5th, by monitoring the respiratory rate of mouse, on the one hand can be controlled according to the frequency of breathing to gas, another aspect
Breathing role in odor discrimination can be studied；
6th, the camera monitoring device used, can detect movement locus of the mouse during experiment at any time, so as to
The effect for being study movement in olfactory function provides a kind of foundation.
Brief description of the drawings
Fig. 1 is overall structure diagram of the present invention.
Fig. 2 is breathing sleeve structure schematic diagram figure.
Fig. 3 is gas generation apparatus structural representation.
Fig. 4 is circuit diagram of the present invention.
In figure, 1- cameras, 2- poles, 3- micro controllers, 4- displays, 5- baroceptors, 6- amplifiers, 7- flues
Road, 8- gas generation apparatus, 9- infrared tubes, 10- mouse, 11- training place, 12- conduits cap, 13- conduits, 14- nasal cavities,
15- odor bottles, 16- magnetic valves, 17- relays, 18- air pressure pumps, 19- flowmeters.
Embodiment
The invention will be further described with specific embodiment below in conjunction with the accompanying drawings.
Fig. 1, Fig. 2, Fig. 3, Fig. 4 schematically show of the invention a kind of record conscious mouse respiratory movement and habituation with
Go the structure of habituation device.
It is as shown in Figure 1, Figure 2, Figure 3, Figure 4, a kind of to record conscious mouse respiratory movement and habituation and remove habituation device,
It is characterized in that：It includes being used to detect mouse breathing situation and generates the breathing tape deck of corresponding event signal, for supervising
Survey mouse movement situation and generate the movement locus monitoring device of corresponding motor message, for monitoring mouse to Odor stimulation or habit
Usedization with go habituation training mission and generate corresponding detection signal to device of air, for receiving event signal, motor message
The micro controller for analyzing and processing and showing with detection signal；
Described breathing tape deck, movement locus monitoring device and the output end to device of air respectively connected micro controller
Input, event signal, motor message and detection signal are analyzed and processed by micro controller, finally mouse exhaled
The physiology and appearance of suction, smell and motion monitor and record in real time.
As shown in Figure 1 and Figure 2, described breathing tape deck includes breathing sleeve pipe, small hose, baroceptor and amplification
Device；Described breathing sleeve pipe is made up of conduit and conduit cap, and conduit cap sleeve is connected on conduit, and one end insertion mouse of its conduit is fitted
In the nasal cavity for closing position, the other end is connected to the small hose of good, the suitable diameter of sealing.
As shown in Figure 1 and Figure 2, described baroceptor is caused jewelry, expensive clothing and other valuables in the expiration of detection mouse and breathing process
The change of intraductal atmospheric pressure and generate breathing induced signal, the baroceptor described in it is located in small hose, baroceptor
Output end is connected to amplifier.
As shown in Figure 1 and Figure 2, described amplifier is that the breathing induced signal that will be recorded amplifies, the input of amplifier
Baroceptor is connected to, output end is connected to micro controller, so that the breathing induced signal after amplification is sent into micro controller
Shown.
As shown in Figure 1 and Figure 2, it is the surgical procedure for breathing sleeve pipe loading mouse nasal cavity is as follows：On the mouse nasal cavity of anesthesia
Broken bone in the aperture and cleaning hole of drill with ferrule proper diameter, one end of conduit is inserted in the hole, around wrapped up with dental cement
Get up, after treating that cement is dried, conduit cap is inserted into the other end of conduit and tightened, to prevent blocking nasal cavity；In surgical procedure,
In order to judge the accurate of catheter insertion site, therefore before insertion, a small amount of physiological saline is first dripped in the top in hole, observation water
Whether face is fluctuated therewith breathing, and illustrates that position is accurate if having fluctuation；After operation is completed, it is pre- to give mouse anti-infectives
It is anti-, it is placed in rest 3-5 days in cage；After state recovery after can recording respiration, conduit cap is unscrewed and taken out, connect small hose,
Baroceptor and signal amplifier etc.；If not recorded breathing for the first time, need to be rapidly injected air with 1ml syringes
Make its unobstructed untill it recorded breathing, also need to observe the state of mouse in venting process, to prevent the excessive air of injection
It is damaged to alveolar tissue etc..
As shown in Figure 1 and Figure 2, described breathing tape deck is that the other end connects in the nasal cavity by breathing catheter insertion mouse
Then sealing is good, is adapted to the small hose of diameter；Monitor to breathe the change of induced signal, Jin Ertong by baroceptor
Induced signal amplification will be breathed by crossing signal amplifier, and the breathing induced signal after amplification is sent into micro controller, now micro-control
Device is acquired to breathing induced signal and shows corresponding data by display screen, so as to accurately realize respiratory rate with
And the record of amplitude.
As shown in Figure 1, Figure 3, it is described to include training place and multi-channel gas generation device to device of air.
As shown in Figure 1, Figure 3, described training place be mouse in certain spacious space can free activity place.
As shown in Figure 1, Figure 3, described multi-channel gas generation device is by gas pipeline, flowmeter, magnetic valve, smell
Bottle, air pressure pump, connecting tube, relay and infrared tube composition；Described gas pipeline one end connection odor bottle, the other end
Connect training place；A certain proportion of odor liquids are provided with inside described odor bottle；Described air pressure pump connection odor bottle,
Give odor bottle certain air pressure by air pressure pump, by the control of flowmeter, so as to which the smell in odor bottle be passed through
Gas pipeline is transported to training place so that mouse sucks smell and realizes the stimulation of smell.
As shown in Figure 1, Figure 3, described odor bottle is provided with multiple, and a kind of odor liquids are loaded with each odor bottle；Institute
The connecting tube stated be provided with it is multiple, one end of connecting tube is connected to the output end of air pressure pump, and the other end is connected to a smell
Bottle.
As shown in Figure 1, Figure 3, described magnetic valve is provided with multiple, and magnetic valve is located in connecting tube, in each connecting tube
Provided with a magnetic valve, its magnetic valve is connected to relay；Described relay input is connected to micro controller.
As shown in Figure 1, Figure 3, described micro controller sends control instruction to relay, so as to one electromagnetism of Control
Valve is opened so that gas caused by air pressure pump passes through odor bottle corresponding to the magnetic valve, so as to which gas carries the odor bottle
The smell of interior odor liquids, and exported by gas pipeline, mouse can receive the thorn of smell by the end of gas pipeline
Swash.
As shown in Figure 1, Figure 3, described flowmeter is located on gas pipeline, and the output end of flowmeter is connected to micro controller,
When gas flows in odor bottle, flowmeter generation flow signal is sent to micro controller, so as to which micro controller passes through data acquisition module
Flow signal is acquired.
As shown in Figure 1, Figure 3, described infrared tube is located at the side of gas pipeline gas outlet in training place, and its is infrared right
The output end of pipe is connected to micro controller, and described infrared tube can monitor that mouse exploration goes the action signal of smelling the moment
And the time of smelling, and transmit this information to micro controller.
As shown in Figure 1, Figure 3, when experiment starts, it would be desirable to which the mouse being trained shifts to an earlier date ten minutes and is placed on training place
Institute, and then allow mouse to adapt to environment, the switch of flowmeter is next adjusted to the scale of very little, and dress is produced by multi-channel gas
Put and give a kind of smell, continue two minutes, after depressed beam two minutes, multi-channel gas generation device repeats the behaviour of the above
Make, be repeated 4 times with this；To the 5th, another smell will be given to gas system, repeats the operation of the above.
As shown in Figure 1, Figure 3, described gas pipeline is replaceable pipeline, causes dirt so as to avoid obscuring for smell
Dye.
As shown in Figure 1, Figure 3, described training place be for mouse activity place, its will need be trained it is small
Mouse is placed on training place, and then allows mouse to adapt to environment.
As shown in figure 1, described micro controller is connected with computer communication, so as to check exhaling for mouse by computer
The physiology and appearance data message of suction, smell and motion.
As shown in figure 1, described movement locus monitoring device includes being used for the shooting for monitoring and recording mouse movement track
Head and pole, described camera, which is located at, can monitor the top of mouse movement track, and camera is connected to micro controller, so as to by institute
The motor message collected is sent to micro controller, and micro controller is shown to being sent to after motor message processing on display；Institute
The pole stated is used for fixing camera.
As Figure 1 and Figure 4, electronic switch is additionally provided between camera and micro controller connection, the input of its electronic switch
Micro controller is connected to, output end is connected to camera；During experiment, micro controller sends control instruction to electronic switch, from
And control the opening of electronic switch so that camera starts to image, and the information transmission for monitoring toy is preserved simultaneously to micro controller
Corresponding computer is transmitted this information to by micro controller, so as to check fortune of the toy in experimentation by computer
Dynamic state.
As shown in Figure 1, Figure 2, Figure 3, Figure 4, the standard value of mouse breathing frequency, mouse breathing are provided with described micro controller
Respiratory rate in the case of metastable within the specific limits (general 2-5Hz), when baroceptor detects mouse
When respiratory rate is below or above standard value, micro controller produces control instruction and is sent to relay so that relay connection
Magnetic valve obtains electric and adhesive, so as to which the air in odor bottle is flowed into training place by gas pipeline, supplies mouse breathing institute
The stimulation of the air and smell that need.
As shown in Figure 1, Figure 2, Figure 3, Figure 4, the information that described micro controller is transmitted by flowmeter is and to gas flow
Data are acquired, while can also be triggered by the change for the respiratory rate that recorded to device of air；Mouse breathing is relative
In the case of stable, to give mouse certain density Odor stimulation to device of air so as to trigger.
As shown in Figure 1, Figure 2, Figure 3, Figure 4, the present apparatus is additionally provided with controlling switch, and controlling switch is connected to power supply, and its is another
End connects each electronic device respectively, so as to open by controlling switch when needing to start experiment and can provide electric energy to the present apparatus,
Consequently facilitating the work of each electronic device.
As shown in Figure 1, Figure 2, Figure 3, Figure 4, OPA234 models amplifier or AD620BR models can be selected in described amplifier
Amplifier etc..
As shown in Figure 1, Figure 2, Figure 3, Figure 4, described micro controller use can analyze, control, the micro controller of timing and storage
(such as：424-CHIPKIT-UC32 micro controllers, EP1K100QC208-3 micro controllers or 410-301 micro controllers etc.).
Above-described is only some embodiments of the present invention.For the person of ordinary skill of the art, not
On the premise of departing from the invention design, at least one modification and improvement can also be made, these belong to the guarantor of the present invention
Protect scope.
Claims (10)
1. one kind record conscious mouse respiratory movement and habituation are with removing habituation device, it is characterised in that：It includes being used to examine
Survey mouse breathing situation and generate the breathing tape deck of corresponding event signal, for monitoring mouse movement situation and generating correspondingly
The movement locus monitoring device of motor message, for monitoring mouse to Odor stimulation or habituation and going habituation training mission simultaneously
The corresponding detection signal of generation gives device of air, for receiving the micro-control of event signal, motor message and detection signal analyzing and processing
Device；For showing the display of each data, described display is connected to micro controller；
Described breathing tape deck, movement locus monitoring device and the output end to device of air respectively connected the defeated of micro controller
Enter end, event signal, motor message and detection signal are analyzed and processed by micro controller, finally the breathing to mouse, gas
Taste and the physiology and appearance of motion are monitored in real time.
2. with removing habituation device, it is special for a kind of record conscious mouse respiratory movement according to claim 1 and habituation
Sign is：Described breathing tape deck includes breathing sleeve pipe, small hose, baroceptor and amplifier；Described breathing set
Pipe is made up of conduit and conduit cap, and conduit cap sleeve is connected on conduit, in the nasal cavity of one end insertion mouse suitable position of its conduit,
The other end is connected to the small hose of good, the suitable diameter of sealing.
3. with removing habituation device, it is special for a kind of record conscious mouse respiratory movement according to claim 2 and habituation
Sign is：Described baroceptor be detect mouse exhale and breathing process in caused soft intraductal atmospheric pressure change and
Generation breathing induced signal, the baroceptor described in it are located in small hose, and the output end of baroceptor is connected to amplify
Device.
4. with removing habituation device, it is special for a kind of record conscious mouse respiratory movement according to claim 2 and habituation
Sign is：Described amplifier is the breathing induced signal amplification that will be recorded, and the input of amplifier is connected to air pressure sensing
Device, output end are connected to micro controller, and so as to which the breathing induced signal after amplification is sent into micro controller, micro controller is to induced signal
Display is sent to after being handled and is shown.
5. with removing habituation device, it is special for a kind of record conscious mouse respiratory movement according to claim 1 and habituation
Sign is：Described movement locus monitoring device includes being used for camera and the pole for monitoring and recording mouse movement track, institute
The camera stated is located at the top that can monitor mouse movement track, and camera is connected to micro controller, so as to the fortune that will be collected
Dynamic signal is sent to micro controller, and micro controller is shown to being sent to after motor message processing on display；Described pole is used
In fixing camera.
6. with removing habituation device, it is special for a kind of record conscious mouse respiratory movement according to claim 1 and habituation
Sign is：Described includes training place and multi-channel gas generation device to device of air；Described training place is that mouse exists
In certain spacious space can free activity place.
7. with removing habituation device, it is special for a kind of record conscious mouse respiratory movement according to claim 6 and habituation
Sign is：Described multi-channel gas generation device by gas pipeline, flowmeter, magnetic valve, odor bottle, air pressure pump, after
Electrical equipment and infrared tube composition；Described gas pipeline one end connection odor bottle, other end connection training place；Described odor bottle
The inside is provided with a certain proportion of odor liquids；Described air pressure pump connection odor bottle, smell is given by air pressure pump
The certain air pressure of bottle, by the control of flowmeter, so as to which the smell in odor bottle is transported into training place by gas pipeline, make
Obtain mouse suction smell and realize the stimulation of smell.
8. with removing habituation device, it is special for a kind of record conscious mouse respiratory movement according to claim 7 and habituation
Sign is：Described magnetic valve is connected in connecting tube, and its magnetic valve is connected to relay；Described relay input connection
Micro controller；Described flowmeter is located on gas pipeline, and the output end of flowmeter is connected to micro controller.
9. with removing habituation device, it is special for a kind of record conscious mouse respiratory movement according to claim 7 and habituation
Sign is：Described infrared tube is located at the side of gas pipeline gas outlet in training place, the output end connection of its infrared tube
Micro controller, described infrared tube can monitor that mouse exploration goes the action signal of smelling the moment, and the information is passed
It is sent to micro controller.
10. with removing habituation device, it is special for a kind of record conscious mouse respiratory movement according to claim 1 and habituation
Sign is：Data acquisition module is provided with described micro controller, so as to be acquired by data acquisition module to each data
And preserve；Described micro controller is provided with can be compatible with the amplifier, camera, relay, flowmeter and infrared tube
Communication control interface.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201711248424.XA CN107874743B (en) | 2017-12-01 | 2017-12-01 | Device for recording respiratory movement and habituation and de-habituation of awake mice |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711248424.XA CN107874743B (en) | 2017-12-01 | 2017-12-01 | Device for recording respiratory movement and habituation and de-habituation of awake mice |
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| CN107874743A true CN107874743A (en) | 2018-04-06 |
| CN107874743B CN107874743B (en) | 2024-06-07 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114391809A (en) * | 2021-12-23 | 2022-04-26 | 中国科学院心理研究所 | Non-reporting type olfactory function checking equipment and checking method thereof |
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