CN107865778A - A kind of oily gel composition and its preparation method and application - Google Patents
A kind of oily gel composition and its preparation method and application Download PDFInfo
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- CN107865778A CN107865778A CN201711113019.7A CN201711113019A CN107865778A CN 107865778 A CN107865778 A CN 107865778A CN 201711113019 A CN201711113019 A CN 201711113019A CN 107865778 A CN107865778 A CN 107865778A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/21—Emulsions characterized by droplet sizes below 1 micron
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/49—Solubiliser, Solubilising system
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Abstract
The invention discloses a kind of oily gel composition and its preparation method and application, comprising：Nonionic surfactant 2 30%；Grease 20 60%；Polyalcohol 15 40%；Water, surplus.Its preparation method includes：By nonionic surfactant, polyalcohol, water, low-grade fever dissolving is well mixed in proportion, is designated as A；Under A stirring conditions, grease is slowly added into, is designated as B；Under B stirring conditions, it will be slowly added into after remaining polynary alcohol and water premix, stir evenly and produce.Oil content is high contained by the oily gel composition of the present invention, can be widely applied to the formula such as toner, elite, facial mask, spraying, while can reduce the use of some solubilizer as the solubilizer of spices and essence in formula, reduces product excitant；Oily gel composition stability is good, and particle diameter concentrates on 100 150nm, modest viscosity, and easily stored, transport and easy to use；Preparation technology is simple, and energy consumption is low, and without high temperature and high pressure homogeneous, financial cost is low, green safe, has good prospects for commercial application.
Description
Technical field
The present invention relates to cosmetic field, more particularly to a kind of oily gel composition and its preparation method and application.
Background technology
Nanoemulsions are a kind of aqueous colloidal dispersions between microemulsion and ordinary emulsion, usually contain water, oil and surface
Activating agent, some also contain cosurfactant, can deliver the both effectiveness composition of lipophilic class.At present, the temporary nothing of nanoemulsions implication
Explicitly define, what is generally approved is the particle size one of dispersed phase drop particle between microemulsion and simple emulsion
As 50~500 nm a kind of emulsion, transparent, translucent or milky is presented in the difference of appearance particle diameter.Compared to common breast
Liquid, nanoemulsions have the advantages that small size droplet diameter, uniform particle diameter and long-time stability are high, and with very big specific surface area and
Free energy, contribute to the dissolving of bioactive substance, be a kind of effective transmission system, be widely used in medicine, cosmetics
Deng field.
Nanoemulsions are applied to mainly have following several respects advantage in cosmetics：Promote the infiltration of active component；Its emulsion
The stability of system is good, is not susceptible to be layered, phenomena such as flocculating, gather and precipitate；The nanoemulsions of appropriate particle diameter will not destroy
Healthy skin and cell, therefore available for the exploitation of curative effect-type product.
Under normal circumstances, nanoemulsions can not spontaneously form, and its preparation method substantially has high energy emulsion process and low-energy emulsification
The class of method two.High energy emulsion process often borrows the equipment such as ultrasonic wave, high-pressure homogeneous, relies on high mechanical energy and breaks the dispersed phase particles of system
It is broken；And low-energy emulsification fado prepares emulsion such as phase transition temperature (PIT) method by phase conversion method.But the method pair of the above is set
Standby or technological requirement is higher, and large-scale production acquires a certain degree of difficulty.At present, the making of the nanoemulsions product of in the market is most
Or pass through high-pressure emulsification machine, the processing of high-pressure homogeneous equipment.
Therefore, develop a kind of preparation technology it is simple, it is energy-saving, be easily achieved large-scale production, by simply diluting
The oily gel composition that can be prepared by required nanoemulsions has important practical significance and application prospect.
The content of the invention
In view of this, primary and foremost purpose of the invention is to overcome above-mentioned the shortcomings of the prior art, there is provided a kind of oil is solidifying
Glue composition, oil content contained by the oily gel composition is high, stability is good, can be widely applied to toner, elite, facial mask, spraying
Required nanoemulsions product is made Deng formula, while some solubilisings can be reduced as the solubilizer of spices and essence in formula
The use of agent, reduce product excitant.
Another object of the present invention is to provide the preparation method of above-mentioned oily gel composition, this method is simple, and energy consumption is low,
Without high temperature and high pressure homogeneous.
The technical solution adopted by the present invention is as follows：
A kind of oily gel composition, by weight percentage, include following component：
Nonionic surfactant 2-30%
Grease 20-60%
Polyalcohol 15-40%
Water surplus.
It is further preferred that described oily gel composition, by weight percentage, includes following component：
Nonionic surfactant 15-25%
Grease 30-49%
Polyalcohol 25-35%
Water surplus.
Described nonionic surfactant be polyol type surfactant, preferably PEG-60 rilanit specials,
PEG-20 iso stearic acid of glycerine ester, Natrulon H-10 isostearate or the one or more of of Natrulon H-10 dioleate mix
Close.
The polyalcohol is one or more of in glycerine, 1,3 butylene glycol, 1,2- propane diols, 1,3- propane diols or diglycerol
Mixing, preferably glycerine or diglycerol.
The grease is one or more of mixing in the oil of artificial oil, mineral oil, silicone oil, hydrocarbon ils or plant origin,
Preferably glycerine three（Thylhexoic acid）One or more of mixing in ester or caprylic/capric triglyceride.
The oily gel composition is to be clear to translucent, preferably clear state.
Its particle diameter of the oily gel composition is less than 200nm, viscosity 1000mpas- through the test of Malvern particle instrument
500000mpas, preferable particle size 100-150nm, preferred viscosities 150000mpas-250000mpas.
Present invention also offers the preparation method of above-mentioned oily gel composition, comprise the following steps：
（1）By nonionic surfactant, polyalcohol, water, low-grade fever dissolving is well mixed in proportion, is designated as A, wherein nonionic table
Face activating agent：Polyalcohol：Water=1 ~ 2:1~2：（0~4）, the low-grade fever is the temperature not higher than 45 °C；
（2）Under A stirring conditions, grease is slowly added into, is designated as B；
（3）Under B stirring conditions, it will be slowly added into after remaining polynary alcohol and water premix, stir evenly and produce.
Present invention also offers application of the above-mentioned oily gel composition in cosmetics.
Present invention also offers a kind of cosmetics, include above-mentioned oily gel composition.
In the oily gel composition of the invention described above, in the range of effect of the present invention is not damaged, can arbitrarily it coordinate
The composition that generally may be fitted in cosmetics prepares cosmetics.This any condition includes preservative, NMF, ultraviolet
Absorbent, antioxidant, pH adjusting agent, pigment, active matter etc., its dosage are to prepare the conventional amount used of cosmetics, the cosmetic
Product can be toner, elite, facial mask, spraying etc..
The present invention compared with prior art, has the advantages that：
（1）Oil content contained by gained oily gel composition of the invention is high, and required nanoemulsions are can be prepared by by simply diluting, can be wide
It is general to be applied in the formula such as toner, elite, facial mask, spraying, while also can reduce certain as the solubilizer of spices and essence
The use of a little solubilizer, reduces product excitant；
（2）Gained oily gel composition stability of the invention is good, and particle diameter is less than 200nm, modest viscosity, and easily stored, transport
It is and easy to use；
（3）The preparation technology of the present invention is simple, and without high temperature and high pressure homogeneous, financial cost is low, green safe, has well
Prospects for commercial application.
Embodiment
The present invention is further illustrated below by embodiment, but embodiments of the present invention are not by following realities
Apply the limitation of example.
Raw material used in the embodiment of the present invention and comparative example derives from purchased in market.
Particle diameter method of testing:Using Malvern laser particle analyzer Mastersizer 3000, oily gel composition is used in advance
Deionized water is diluted to 2% solution, then is determined with Malvern laser particle analyzer Mastersizer 3000.
Viscosity determining procedure：Tested using model DV-C digital displays viscosimeter, select suitable rotor and rotating speed（4#1r）
Afterwards, directly rotor is inserted in the oily gel composition without any processing and determined, treat the basicly stable reading of numerical value.
Embodiment 1：
It is formulated by table 1 Suo Shi, nonionic surfactant, polyalcohol, water is well mixed in 40 °C of dissolvings in proportion, A is designated as,
Wherein nonionic surfactant：Polyalcohol：Water=1:1:0.05；Under A stirring conditions, grease is slowly added into, is designated as B；
Under B stirring conditions, it will be slowly added into after remaining polynary alcohol and water premix, stir evenly and produce oily gel composition, test performance knot
Fruit is as shown in table 1.
Embodiment 2：
Wherein nonionic surfactant：Polyalcohol：Water=1:1:0.1；
Remaining is the same as embodiment 1.
Embodiment 3：
Wherein nonionic surfactant：Polyalcohol：Water=1:1:0；
Remaining is the same as embodiment 1.
Embodiment 4：
Wherein nonionic surfactant：Polyalcohol：Water=1:1:0.15；
Remaining is the same as embodiment 1.
Embodiment 5：
Wherein nonionic surfactant：Polyalcohol：Water=1:1:0；
Remaining is the same as embodiment 1.
Embodiment 6：
Wherein nonionic surfactant：Polyalcohol：Water=1:1:0；
Remaining is the same as embodiment 1.
Comparative example 1：
It is formulated by table 1 Suo Shi, nonionic surfactant, polyalcohol, water is well mixed in 40 °C of dissolvings, it is designated as A；Stirred in A
Under the conditions of mixing, grease is slowly added into, stirs evenly and produces, test performance result is as shown in table 1.
The composition and the performance test results of the embodiment of table 1 and comparative example（Percentage by weight）
The present invention is by formula rate optimization and process optimization it can be seen from the embodiment of table 1 and comparative example, the oil being prepared
Gel combination particle diameter integrated distribution, modest viscosity, preparation technology is simple, and energy consumption is low, without high temperature and high pressure homogeneous.
Claims (10)
1. a kind of oily gel composition, it is characterised in that by weight percentage, include following component：
Nonionic surfactant 2-30%
Grease 20-60%
Polyalcohol 15-40%
Water surplus.
2. oily gel composition according to claim 1, it is characterised in that by weight percentage, include following component：
Nonionic surfactant 15-25%
Grease 30-49%
Polyalcohol 25-35%
Water surplus.
3. oily gel composition according to claim 1 or 2, it is characterised in that described nonionic surfactant is
The surfactant of polyol type, preferably PEG-60 rilanit specials, PEG-20 iso stearic acid of glycerine ester, Natrulon H-10 are different
One or more of mixing in stearate or Natrulon H-10 dioleate.
4. oily gel composition according to claim 1 or 2, it is characterised in that the polyalcohol is glycerine, 1,3- fourths two
One or more of mixing, preferably glycerine or diglycerol in alcohol, 1,2-PD, 1,3-PD or diglycerol.
5. oily gel composition according to claim 1 or 2, it is characterised in that the grease be artificial oil, mineral oil,
One or more of mixing in the oil of silicone oil, hydrocarbon ils or plant origin, preferably glycerine three（Thylhexoic acid）Ester or octanoic acid/last of the ten Heavenly stems
One or more of mixing in acid glycerol three ester.
6. oily gel composition according to claim 1 or 2, it is characterised in that the oily gel composition is to be clear to
Translucent, preferably clear state, its particle diameter are less than 200nm, viscosity 1000mpas- through the test of Malvern particle instrument
500000mpas, preferable particle size 100-150nm, preferred viscosities 150000mpas-250000mpas.
7. the preparation method of the oily gel composition according to claim any one of 1-6, it is characterised in that including following step
Suddenly：
（1）By nonionic surfactant, polyalcohol, water, low-grade fever dissolving is well mixed in proportion, is designated as A, wherein nonionic table
Face activating agent：Polyalcohol：Water=1 ~ 2:1~2：（0~4）, the low-grade fever is the temperature not higher than 45 °C；
（2）Under A stirring conditions, grease is slowly added into, is designated as B；
（3）Under B stirring conditions, it will be slowly added into after remaining polynary alcohol and water premix, stir evenly and produce.
8. application of the oily gel composition described in claim any one of 1-6 in cosmetics.
9. a kind of cosmetics, include the oily gel composition described in claim any one of 1-6.
10. cosmetics according to claim 9, it is characterised in that the gross weight based on cosmetics, the oleogel combination
The addition of thing is 0.01-20%.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201711113019.7A CN107865778A (en) | 2017-11-13 | 2017-11-13 | A kind of oily gel composition and its preparation method and application |
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| CN201711113019.7A CN107865778A (en) | 2017-11-13 | 2017-11-13 | A kind of oily gel composition and its preparation method and application |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108635252A (en) * | 2018-06-11 | 2018-10-12 | 广东芭薇生物科技股份有限公司 | A kind of emulsifying toner and preparation method thereof |
| CN109172479A (en) * | 2018-10-09 | 2019-01-11 | 湖南御家化妆品制造有限公司 | The preparation method of facial mask liquid |
| CN114642600A (en) * | 2022-03-12 | 2022-06-21 | 广州悦荟化妆品有限公司 | Oil gel composition, non-emulsified mask liquid composition, and preparation method and use method thereof |
| CN115120520A (en) * | 2022-05-06 | 2022-09-30 | 彭氏(惠州)实业发展有限公司 | Cosmetic composition comprising myrtle ketone and cosmetic use thereof |
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| CN107028881A (en) * | 2015-10-23 | 2017-08-11 | 长春纳米生技公司 | With reversible continuous and dispersed phase nanoemulsions |
| CN107252400A (en) * | 2017-06-12 | 2017-10-17 | 上海应用技术大学 | Vegetable fat nanoemulsions prepared by a kind of use D phases emulsion process and preparation method thereof |
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2017
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| KR20090073368A (en) * | 2007-12-31 | 2009-07-03 | (주)아모레퍼시픽 | A stable nano-emulsion with narrow particle size distribution |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108635252A (en) * | 2018-06-11 | 2018-10-12 | 广东芭薇生物科技股份有限公司 | A kind of emulsifying toner and preparation method thereof |
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| CN109172479A (en) * | 2018-10-09 | 2019-01-11 | 湖南御家化妆品制造有限公司 | The preparation method of facial mask liquid |
| CN114642600A (en) * | 2022-03-12 | 2022-06-21 | 广州悦荟化妆品有限公司 | Oil gel composition, non-emulsified mask liquid composition, and preparation method and use method thereof |
| CN115120520A (en) * | 2022-05-06 | 2022-09-30 | 彭氏(惠州)实业发展有限公司 | Cosmetic composition comprising myrtle ketone and cosmetic use thereof |
| CN115120520B (en) * | 2022-05-06 | 2024-07-19 | 彭氏(惠州)实业发展有限公司 | Cosmetic composition containing myrtle ketone and cosmetic application thereof |
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Address after: 511434 No. 13, Liu Wei street, Hualong Town, Panyu District, Guangzhou, Guangdong Applicant after: Hua An Tang biotech Group Co., Ltd. Address before: 511434 No. 13, Liu Wei street, Hualong Town, Panyu District, Guangzhou, Guangdong Applicant before: City flower An Tang bio tech ltd, Guangzhou |
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