CN107854540B

CN107854540B - External traditional Chinese medicine formula essential oil for treating haemorrhoids

Info

Publication number: CN107854540B
Application number: CN201711424960.0A
Authority: CN
Inventors: 苗明三; 张德芹; 苗艳艳; 方晓燕
Original assignee: Henan University of Traditional Chinese Medicine HUTCM
Current assignee: Henan University of Traditional Chinese Medicine HUTCM
Priority date: 2017-12-25
Filing date: 2017-12-25
Publication date: 2020-10-30
Anticipated expiration: 2037-12-25
Also published as: CN107854540A

Abstract

The invention relates to an external traditional Chinese medicine essential oil for treating hemorrhoids, which can effectively solve the problem of treatment medication of hemorrhoids and adopts the technical scheme that: the Chinese medicinal composition is prepared by uniformly mixing peach flower essential oil, safflower essential oil, Chinese trumpet creeper essential oil, mint ice = (1.8-2.2): 0.8-1.2): 2.5-3.5): 0.8-1.2.

Description

External traditional Chinese medicine formula essential oil for treating haemorrhoids

Technical Field

The invention relates to medicine, in particular to externally applied essential oil (also called as red peach blossom essential oil) in a traditional Chinese medicine formula for treating hemorrhoids.

Background

Hemorrhoids (Hemorrhoids or Piles), also known as Hemorrhoids, hemorrhoidal disease, hemorrhoid diseases, etc., are chronic diseases in which the venous plexus of the anorectal base and the anal mucosa is varicose to form one or more soft venous masses. The hemorrhoids are located in the mucous membrane inside the anus and called internal hemorrhoids, and located in the vicinity of the inside of the anus and called external hemorrhoids, both of which are called mixed hemorrhoids. Currently, British scholars are mostly called Piles and American scholars are called Hemorrhoids. The former is named from the appearance of the hemorrhoid like the ball, the latter is named from bleeding as the clinical feature, which refers broadly to internal and external hemorrhoids. The patients with light hemorrhoids have inconvenience for the normal life of people, and the serious patients have health influence. If the hematochezia lasts for a long time, anemia of different degrees and even hemorrhagic shock can be caused, so that the life is threatened; when the hemorrhoid is necrotic and the infection is serious, the infection can pass through the blood system to cause the systemic infection, and the consequence is serious.

The clinical manifestations are as follows:

1. it is mainly manifested as hemafecia, which is characterized by painless, intermittent, fresh blood after defecation, blood dripping or bloody hand paper in defecation, constipation, alcohol drinking or aggravated by eating irritant food.

2. Simple internal hemorrhoid has no pain, only has the feeling of falling and swelling, can bleed, develops to prolapse, and has pain when combined with thrombosis, incarceration and infection.

3. The internal hemorrhoids are divided into 4 degrees. Bleeding during defecation at degree I, the bleeding can be stopped automatically after defecation, and the hemorrhoid does not fall out of the anus; II, frequent stool blood; the excrement falls out of the anus during defecation, and is automatically returned after defecation; ③ after the III degree hemorrhoids are separated, the auxiliary reduction is carried out by hands; IV degree hemorrhoids are outside the anus for a long time and cannot be accommodated; wherein, the internal hemorrhoids above II degree mostly form mixed hemorrhoids, and the symptoms of the internal hemorrhoids and the external hemorrhoids exist simultaneously, so that the pain and the pruritus can appear, wherein the pruritus is usually caused by viscous secretion flowing out when the hemorrhoids are prolapsed. The latter three degrees are more than the mixed hemorrhoid.

4. External hemorrhoids usually have no special symptoms, and can cause swelling and pain when thrombosis and inflammation occur.

Although various medicaments for treating hemorrhoids exist at present, the use of the medicaments is not satisfactory for various reasons, so that the improvement and innovation of the medicaments for treating the hemorrhoids are imperative.

Disclosure of Invention

Aiming at the situation, in order to overcome the defects of the prior art, the invention aims to provide the externally-applied essential oil with the traditional Chinese medicine formula for treating the hemorrhoids, which can effectively solve the problem of medicine application for treating the hemorrhoids.

The invention solves the technical scheme that the traditional Chinese medicine formula essential oil for treating hemorrhoids through external application is prepared from the following components in parts by weight: peach flower essential oil, safflower essential oil, Chinese trumpet creeper essential oil, mint ice (1.8-2.2), 0.8-1.2, 2.5-3.5, 0.8-1.2), and mixing uniformly to obtain the product, wherein:

the peach blossom essential oil is prepared by crushing peach blossom into coarse powder which is sieved by a sieve of 10-20 meshes, soaking the coarse powder in a mixed solvent of any one or more than two of ethanol, ethyl acetate or cyclohexane with the weight of 0.5-1.5 times of the weight of medicinal materials for 2-4 min, taking the wet medicinal materials, and performing supercritical CO extraction₂Performing fluid extraction (SFE), wherein the extraction temperature is 42-50 ℃, the extraction pressure is 20-25 MPa, the separation temperature is 50-60 ℃, the separation pressure is 4.5-5.5 MPa, and the extraction time is 1.5-2.5 h to obtain the peach blossom essential oil;

the safflower essential oil is prepared by crushing safflower into coarse powder which is sieved by a sieve of 10-20 meshes, soaking the coarse powder in a mixed solvent of any one or more than two of ethanol, ethyl acetate or cyclohexane with the weight of 0.5-1.5 times of the weight of medicinal materials for 2-4 min, taking the wet medicinal materials, and performing supercritical CO extraction₂Fluid Extraction (SFE), wherein the extraction temperature is 42-50 ℃, the extraction pressure is 20-25 MPa, the separation temperature is 50-60 ℃, the separation pressure is 4.5-5.5 MPa, and the extraction time is 1.5-2.5 h, so that safflower essential oil is obtained;

the campsis essential oil is prepared by crushing campsis grandiflora into coarse powder which is sieved by a sieve of 10-20 meshes, soaking the coarse powder in a mixed solvent of any one or more than two of ethanol, ethyl acetate or cyclohexane in an amount which is 0.5-1.5 times of the weight of medicinal materials for 2-4 min, taking the wet medicinal materials, and performing supercritical CO₂And (2) fluid extraction (SFE), wherein the extraction temperature is 42-50 ℃, the extraction pressure is 20-25 MPa, the separation temperature is 50-60 ℃, the separation pressure is 4.5-5.5 MPa, and the extraction time is 1.5-2.5 h, so that the campsis grandiflora essential oil is obtained.

The traditional Chinese medicine composition has the advantages of rich raw materials, easy production and preparation, convenient use and good effect, can be effectively used for treating hemorrhoids, is an innovation on medicaments for treating hemorrhoids, exploits the medicinal value and the economic value of peach blossom, safflower, Chinese trumpetcreeper and mentholum, and has obvious economic and social benefits.

Detailed Description

The following examples are provided to explain the present invention in detail.

The invention may be embodied in the form of the following examples.

Example 1

In the specific implementation of the invention, the external traditional Chinese medicine essential oil for treating hemorrhoids is prepared from the following components in parts by weight: mixing flos persicae essential oil, Carthami flos essential oil, flos Campsis essential oil, Mentholum, herba Menthae ice, and herba Menthae ice.

The peach flower essential oil, the safflower essential oil and the Chinese trumpet creeper flower essential oil are the same as the invention content and are the same as the following.

Example 2

In the specific implementation of the invention, the external traditional Chinese medicine essential oil for treating hemorrhoids is prepared from the following components in parts by weight: mixing flos persicae essential oil, Carthami flos essential oil, flos Campsis essential oil, Mentholum, herba Menthae ice, and herba Menthae ice at ratio of 1.9: 1.1: 2.6: 1.1.

Example 3

In the specific implementation of the invention, the external traditional Chinese medicine essential oil for treating hemorrhoids is prepared from the following components in parts by weight: mixing flos persicae essential oil, Carthami flos essential oil, flos Campsis essential oil, Mentholum 2.1: 0.9: 3.4: 0.9.

The components of the invention are organically matched and mutually supported, can be effectively used for treating hemorrhoids, and obtains very satisfactory beneficial technical effects through tests, and the test data is as follows:

first, the effect on the hemorrhoid model in mice

1. Experimental Material

1.1 Experimental drugs

The invention relates to a red peach blossom essential oil; mayilong musk hemorrhoid ointment is produced by Mayilong pharmaceutical group GmbH; can be used for treating hemorrhoid and anal fissure due to damp-heat stagnation, with symptoms of stool hemorrhage, pain, and tenesmus; also used for perianal eczema; the usage and dosage are as follows: it is applied topically to affected parts.

20% acetic acid solution (molding agent);

mouse serum interleukin 1 beta (IL-beta), tumor necrosis factor alpha (TNF-alpha) ELISA kit, provided by Nanjing institute of bioengineering.

1.2 Experimental animals

KM mice, male, 144, 18-25g, SPF grade; supplied by Jinanpunyue laboratory animal Breeding Co., Ltd, and has the certification number of 37005400000035.

2. Experimental methods

2.1 animal feeding

Constant temperature 23 deg.C, humidity 50%, artificial lighting 12 hours day and 12 hours night alternating, giving regular laboratory diet without restriction of drinking water.

2.2 Molding method

60 mice were taken and fed adaptively for 3 days, and on day 4, 0.05ml of 20% acetic acid solution was pushed into the anus of each mouse (the blank group was given the corresponding dose of physiological saline), and the solution was kept for 1 min. The following day, the mixture was divided into 5 groups of 12 animals according to the degree of swelling and ulceration. Namely a blank group, a model group, a Mayilong hemorrhoid ointment group, a large and small dosage group of the red peach flower essential oil (the small dosage group is the red peach flower essential oil diluted by one time of liquid paraffin). The drug administration is started on the 2 nd day of the model building, the corresponding drugs are coated on the local parts of the hemorrhoids, the dosage of the red peach blossom essential oil is about 0.03 ml/per hemorrhoid, the dosage of the Mayilong hemorrhoid ointment is a layer of local coating, the model group and the blank group are coated with liquid paraffin (0.03 ml/per hemorrhoid), the liquid paraffin is coated once in the morning and at night every day, and the drug administration is continuously carried out for 7 days. The mice were sacrificed 1h after the last day of dosing, the straight intestine was taken, and the lesion grade was observed; blood was collected from the eye and interleukin 1 beta (IL-beta) and tumor necrosis factor alpha (TNF-alpha) were measured in the serum.

2.3 statistical methods

The experimental data were processed with SPSS22.0 statistical software and the data were processed with

Showing that the comparison among groups adopts t test

3. Results of the experiment

3.1 Effect on local Scoring in the hemorrhoid model in mice

TABLE 1 influence of nectarine essential oil on local lesions of hemorrhoid model in mice

Note: 0-complete healing; 1-basic healing; 2-a little ulcer exudate; 3-ulcer oozing liquid;

through Ridit test, compared with a blank group, the model group has obvious pathological change (P is less than 0.01), which indicates that the mouse model for treating the haemorrhoids is successful; compared with the model group, the large and small dose groups of the red peach blossom essential oil and the Mayilong hemorrhoid ointment group can obviously reduce the local lesion (P is less than 0.01) of the hemorrhoid model.

3.2 Effect on serum TNF-alpha, IL-1 beta levels in mouse hemorrhoid models

TABLE 2 Effect of nectarine essential oil on serum TNF-alpha and IL-1 beta levels in a mouse model of hemorrhoids: (

n＝12)

Note: p <0.01 in comparison to model group

As can be seen from the table above, compared with the blank group, the serum TNF-alpha and IL-1 beta levels of the model group are obviously increased (P <0.01), which indicates that the model for producing the haemorrhoids of the mice is successful; compared with the model group, the large and small dose groups of the red peach blossom essential oil and the Mayilong hemorrhoid ointment group can obviously reduce the local lesion (P is less than 0.01) of the hemorrhoid model.

The result shows that the external application of the red peach blossom essential oil has better improvement effect on the mouse hemorrhoid model.

Second, Effect on rat hemorrhoid model

1. Experimental Material

1.1 Experimental drugs

The invention is peach blossom essential oil; mayilong musk hemorrhoid ointment is produced by Mayilong pharmaceutical group GmbH; can be used for treating hemorrhoid and anal fissure due to damp-heat stagnation, with symptoms of stool hemorrhage, pain, and tenesmus; also used for perianal eczema; the usage and dosage are as follows: it is applied topically to affected parts.

Croton oil, Jiangxi Jishui Sanda natural medicinal perfume oil factory; diethyl ether, available from luoyang haohua chemical agents ltd; pyridine, available from miuiou chemical reagents ltd, tianjin; normal saline, available from korn pharmaceuticals, inc; a superoxide dismutase (SOD) kit provided by Nanjing institute of bioengineering; malondialdehyde (MDA) kit provided by Nanjing institute of bioengineering.

1.2 Experimental animals

180 ~ 220g rat, half each sex, Wistar, SPF grade, the experimental animals center in Shandong province provides, quality qualification: no. 37009200004899.

2. Experimental methods

Preparation of croton oil: 1 part of distilled water, 4 parts of pyridine, 5 parts of diethyl ether and 10 parts of 6% croton oil diethyl ether solution.

Taking 60 rats with half of male and female, randomly taking 10 rats as blank control groups, and inserting a cotton ball soaked with 0.16mL of croton oil mixed solution into the anus of the rats for 10s by using the rats of other groups of aether light anesthesia to establish a rat anus croton oil swelling model. The 50 successfully molded rats (male and female halves) were randomly divided into a blank control group, a model group, a Mayilong hemorrhoid ointment group, a large-dose group and a small-dose group (the small-dose group is the red peach essential oil diluted by one time with liquid paraffin). The drug administration is started on the 2 nd day of the model building, the corresponding drugs are coated on the local parts of the hemorrhoids, the dosage of the red peach flower essential oil is about 0.05 ml/per hemorrhoid, the dosage of the Mayilong hemorrhoid ointment is a layer of local hemorrhoid, the model group and the blank group are coated with liquid paraffin (0.05 ml/per hemorrhoid), the liquid paraffin is coated once in the morning and at night every day, and the drug administration is continuously carried out for 7 days. . At 30min after the last dose, each group of rats was sacrificed, rectal tissue 15mm from the anal fur margin was cut and water was blotted with filter paper. Fixing part of tissues by 10% formaldehyde, embedding paraffin, slicing, HE staining, and performing pathological histological observation; part of the tissue is prepared into tissue homogenate, and the contents of MDA and SOD of the anus tissue of each group of rats are measured according to the instruction of a kit.

3, experimental results:

3.1 Effect on MDA and SOD Activity in rat hemorrhoid model local tissues

TABLE 3 Effect of peach blossom essential oil on MDA levels and SOD activity in local tissues of hemorrhoid model in mice: (

n＝10)

Note: p <0.01

As can be seen from the above table, compared with the blank group, the MDA level in the local tissue of the model group is obviously increased (p <0.01), and the SOD activity is obviously reduced (p <0.01), indicating that the modeling is successful. Compared with the model group, the large and small dose groups of the red peach blossom essential oil and the Mayilong hemorrhoid ointment group can obviously reduce the MDA level (p is less than 0.01) in local tissues and obviously increase the SOD activity (p is less than 0.01).

4.2 Effect on local tissue morphology in rat hemorrhoid model

TABLE 4 influence of the essential oil of Prunus persica on the local tissue morphology of the rat model for hemorrhoids

The mucosal layer, the submucosa layer, the muscular layer and the adventitial cells of the rectal canal, blood vessels and muscle tissues are normal under the microscope; "+" mucosal layer: a small amount of inflammatory cell infiltration is seen in the lamina propria; a small amount of inflammatory cells infiltrate the submucosa, and granulation tissues are generated; "+ +" mucous layer: the infiltration of diffusible inflammatory cells is seen in the inherent layer, the infiltration of inflammatory cells is seen in the submucosa, and part of small blood vessels are dilated and hyperemia and endothelial cells are proliferated and swollen; "+ + + +" mucous layer: the columnar epithelium of the single layer is keratinized, and a large amount of infiltration of inflammatory cells, sebaceous glands, small blood vessels and hyperemia appear in the lamina propria; submucosa: a large amount of inflammatory cell infiltration, dense venous extravasated blood expansion, endothelial cell hyperplasia, swelling and granulation tissue generation are seen.

Through Ridit test, compared with a blank group, the model group has obvious pathological change of the hemorrhoids (P is less than 0.01), which indicates that the model is successfully made. Compared with the model group and the model group, the large and small dose groups of the red peach blossom essential oil and the Mayilong hemorrhoid ointment group can obviously reduce the local lesion (P is less than 0.01) of the hemorrhoid model.

Local pathological observation results of all the hemorrhoid models are as follows: the mucosa layer, the submucosa layer, the muscular layer and the adventitia can be seen under a partial rectum speculum of a blank group of rats, the mucosa layer is mainly a single-layer columnar epithelium consisting of absorptive cells and goblet cells, a single tubular large intestinal gland is seen in the inherent layer, and the mucosa layer contains the absorptive cells, a large number of goblet cells, a small number of stem cells and endocrine cells; the submucosa can be seen into arterioles, venules, lymphatic vessels and groups of fat cells; the muscle layer consists of the inner circular muscle and the outer longitudinal muscle. The rectum of the rat in the model group is locally seen, a single-layer columnar epithelium is suddenly changed into a slightly keratinized multi-layer flat epithelium at a dentate line, large sweat glands and abundant sebaceous glands appear in an inherent layer, dense venous plexus is seen in a connective tissue of an anal tube submucosa, venous congestion and expansion, granulation tissue generation and a large amount of inflammatory cell infiltration, namely macrophages, neutrophils and lymphocytes are obtained. The infiltration of inflammatory cells in the inherent layer can be seen under the local microscope of the Mayilong hemorrhoid ointment group, and the infiltration of the granulation tissue, namely, the new capillary vessels, the hyperplastic fibroblasts, the neutrophils, the lymphocytes and the eosinophils, can be seen in the submucosa. In the large-dose group of the red peach essential oil, a small amount of inflammatory cell infiltration is seen in the inherent layer under the local microscope, a small amount of inflammatory cell infiltration is seen in the submucosa, small blood vessels are slightly dilated, and endothelial cells are slightly increased. Inflammatory cell infiltration is seen in the inherent layer under a small-dose local microscope of the red peach blossom essential oil, and macrophages, eosinophilic granulocytes, basophilic granulocytes, occasional plasma cells and small vessel dilatation are seen in the submucosa.

The result shows that the external application of the red peach blossom essential oil has better improvement effect on rat hemorrhoid models.

Thirdly, the external use of the red peach blossom essential oil of the invention treats 62 cases of hemorrhoids

1. Standard of hemorrhoid

The traditional Chinese medicine diagnosis standard is as follows: refer to the Chinese medicine industry Standard of the people's republic of China "Standard of curative Effect for diagnosis of TCM disease symptoms" (ZY/T001.7-94).

(1) Symptoms are: intermittent hematochezia: is characterized by dripping blood and shooting blood when in defecation. Large amount, bright red color, blood not confused with feces. It can also be manifested as bloody toilet paper. And II, prolapse: the granular tumor can be withdrawn from the anus after defecation, can be automatically restored at the initial stage, can be restored after being held back by hands or laid in bed for rest at the later stage, and can be withdrawn when severe people squat, walk, cough or sneeze. ③ discomfort of anus: including anal pendant distention, foreign body sensation, itching or pain, which may be accompanied by mucus overflow.

(2) Physical signs: the mucosa skin at the same position above and below the tooth trace is raised and connected into a whole, and the anus is soft and is positioned at 3, 7 and 11 points.

The diagnosis can be established by including (2) above and (1) above.

Western diagnosis standards for hemorrhoids: refer to the "hemorrhoid clinical diagnosis and treatment guidelines" developed by the rectum and anus external science group of the surgical conference of the Chinese medical society, the anus and intestine conference of the Chinese medical society and the anus and intestine conference of the Chinese traditional and western medical society in 2006.

2. General data

62 patients are out-patient. 32 men and 30 women; age minimum 22 years, maximum 56 years; wherein, 8 cases of internal hemorrhoids, 42 cases of external hemorrhoids and 12 cases of mixed hemorrhoids; the shortest disease course is 1 month, and the longest disease course is 3 years; all patients were not willing to receive surgical treatment. The groups were randomly divided into 2 groups. Treatment groups 32, 16 men and 16 women; 4 cases of internal hemorrhoids, 22 cases of external hemorrhoids and 6 cases of mixed hemorrhoids. Control group 30, male 16, female 14; 4 cases of internal hemorrhoids, 20 cases of external hemorrhoids and 6 cases of mixed hemorrhoids. The two general data are compared and have comparability.

3. Methods of treatment and results

The treatment group is that the red peach blossom essential oil is externally applied for 3 times per day. The anus part is washed clean by clear water after defecation so as to avoid secretion pollution. The control group is topical hemorrhoid ointment of Moschus, 3 times daily. 10 days is 1 course of treatment. Neither use antibiotics.

The curative effect standard is as follows: the evaluation is carried out according to the standard of curative effect of anorectal diseases of traditional Chinese medicine in the traditional Chinese medicine industry Standard of the people's republic of China. The effect is shown: swelling and pain, hemorrhage, and disappearance of exudate, and retraction of hemorrhoid; improvement: swelling and pain, hemorrhage, and exudation disappear, and the retraction degree of hemorrhoid is not less than 2/3; and (4) invalidation: there are symptoms of swelling, bleeding, and exudation, and the retraction degree of hemorrhoid is less than 2/3.

32 cases of treatment groups are cured, 12 cases of treatment are effective, 7 cases of treatment are ineffective, and the total effective rate is 78.1%;

the control group has 30 cases, 10 cases are cured, 9 cases are effective, 11 cases are ineffective, and the total effective rate is 63.3%.

In the experiments, no toxic or side effect or adverse reaction is found, and the medicine is safe to use and stable and reliable in curative effect.

The data clearly show that the invention has rich raw materials, easy production and preparation, convenient use, good treatment effect on the hemorrhoids, high effective rate through clinical application, and unexpected good effect, not only solves the medication problem of the hemorrhoids, but also exploits the medicinal value and the economic value of the peach blossom, the safflower, the trumpet creeper and the menthol, thus being an innovation on the medicaments for treating the hemorrhoids and having obvious economic and social benefits.

Claims

1. The externally-applied traditional Chinese medicine formula essential oil for treating hemorrhoids is characterized by comprising the following components in parts by weight: peach flower essential oil, safflower essential oil, Chinese trumpet creeper essential oil, mint ice = (1.8-2.2): 0.8-1.2): 2.5-3.5): 0.8-1.2), and mixing uniformly to obtain the product, wherein:

the peach blossom essential oil is prepared by crushing peach blossom into coarse powder which is sieved by a sieve of 10-20 meshesSoaking in one or more than two of ethanol, ethyl acetate or cyclohexane in an amount of 0.5-1.5 times of the weight of the medicinal materials for 2-4 min, taking the wet medicinal materials, and performing supercritical CO extraction₂Extracting with a fluid at the extraction temperature of 42-50 ℃, the extraction pressure of 20-25 MPa, the separation temperature of 50-60 ℃, the separation pressure of 4.5-5.5 MPa, and the extraction time of 1.5-2.5 h to obtain the peach blossom essential oil;

the safflower essential oil is prepared by crushing safflower into coarse powder which is sieved by a sieve of 10-20 meshes, soaking the coarse powder in a mixed solvent of any one or more than two of ethanol, ethyl acetate or cyclohexane with the weight of 0.5-1.5 times of the weight of medicinal materials for 2-4 min, taking the wet medicinal materials, and performing supercritical CO extraction₂Fluid extraction is carried out, wherein the extraction temperature is 42-50 ℃, the extraction pressure is 20-25 MPa, the separation temperature is 50-60 ℃, the separation pressure is 4.5-5.5 MPa, and the extraction time is 1.5-2.5 h, so as to obtain safflower essential oil;

the campsis essential oil is prepared by crushing campsis grandiflora into coarse powder which is sieved by a sieve of 10-20 meshes, soaking the coarse powder in a mixed solvent of any one or more than two of ethanol, ethyl acetate or cyclohexane in an amount which is 0.5-1.5 times of the weight of medicinal materials for 2-4 min, taking the wet medicinal materials, and performing supercritical CO₂And (3) fluid extraction, wherein the extraction temperature is 42-50 ℃, the extraction pressure is 20-25 MPa, the separation temperature is 50-60 ℃, the separation pressure is 4.5-5.5 MPa, and the extraction time is 1.5-2.5 h, so that the campsis grandiflora essential oil is obtained.

2. The externally applied traditional Chinese medicine essential oil for treating hemorrhoids as claimed in claim 1, wherein the traditional Chinese medicine essential oil is prepared from the following components in parts by weight: peach flower essential oil, safflower essential oil, Chinese trumpet creeper essential oil, mint ice = 2: 1: 3: 1 and is mixed evenly.

3. The externally applied traditional Chinese medicine essential oil for treating hemorrhoids as claimed in claim 1, wherein the traditional Chinese medicine essential oil is prepared from the following components in parts by weight: mixing flos persicae essential oil, Carthami flos essential oil, flos Campsis essential oil, Mentholum = 1.9: 1.1: 2.6: 1.1.

4. The externally applied traditional Chinese medicine essential oil for treating hemorrhoids as claimed in claim 1, wherein the traditional Chinese medicine essential oil is prepared from the following components in parts by weight: mixing flos persicae essential oil, Carthami flos essential oil, flos Campsis essential oil, Mentholum = 2.1: 0.9: 3.4: 0.9.

5. Use of the essential oil of a Chinese medicinal formulation according to any one of claims 1 to 4 in the manufacture of a medicament for the treatment of hemorrhoids.