CN107854512A - A kind of mouse wine and preparation method thereof - Google Patents
A kind of mouse wine and preparation method thereof Download PDFInfo
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- CN107854512A CN107854512A CN201711318575.8A CN201711318575A CN107854512A CN 107854512 A CN107854512 A CN 107854512A CN 201711318575 A CN201711318575 A CN 201711318575A CN 107854512 A CN107854512 A CN 107854512A
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
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- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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Abstract
The present invention relates to Chinese medicinal liquor technical field, more particularly to a kind of mouse wine and preparation method thereof.The mouse wine of the present invention, give full play to nascent small suckling mouse qi-restoratives and disappear infantile malnutrition due to digestive disturbances or intestinalparasites, the effect of detoxification sore treatment, and make the gradual breaks down into amino acids of protein come into being in small suckling mouse body and dissolve in wine, reach tonic effect, then be aided with Pterospermi Heterophylli clearing damp dehumidifying, it is promoting blood circulation and removing obstruction in channels；Bauhinia champloni dispelling wind and eliminating dampness, proceeds blood cycle；Prinos-like salacia root dispelling wind and eliminating dampness, the effect to restore menstrual flow and invigorate blood circulation, small suckling mouse and the property of medicine of the complementary medicinal material such as Pterospermi Heterophylli, Bauhinia champloni, prinos-like salacia root are combined together, make effect in terms of traumatic injury, relaxing tendons and activating collaterals of mouse wine be strengthened, not overstimulation, and amino acid content is higher than common mouse wine again, it is high a kind of amino acid content is finally given, the property of medicine is moderate, the good mouse wine for the treatment of traumatic injury, relaxing tendons and activating collaterals effect.
Description
Technical field
The present invention relates to Chinese medicinal liquor technical field, more particularly to a kind of mouse wine and preparation method thereof.
Background technology
Cantonese's tradition that always animal such as useful snake, mouse is steep in wine, extensively there are saying for " mouse pushing up three chickens ", such mouse wine always
Once it was the one kind " medicinal liquor " for being popular in In Guangdong Province, also known as mouse son wine.Mouse wine has wind-dispelling to mend body.Clearing and activating the channels and collaterals effect,
Especially there is tonic effect to puerpera.
In Chinese medicine, mouse, be murine Rattus norvegicus and Rattusflauipectus etc. entirety or meat, sweet, mild-natured, returns spleen, stomach,
Disappear infantile malnutrition due to digestive disturbances or intestinalparasites with qi-restoratives, the effect of detoxification sore treatment.Thin thin, the infantile malnutrition for consumptive disease, burn and scald, traumatism and bleeding, pernio, bruise damage
Wound.
The content of the invention
In order to solve above-mentioned technical problem present in prior art, the present invention provides a kind of mouse wine and its preparation side
Method, it is achieved particular by following technical scheme：
A kind of mouse wine, it is prepared by following raw materials in part by weight proportioning：Small suckling mouse 1000-1500 parts, 50-60 ° of white wine
7500-10000 parts, Pterospermi Heterophylli 150-250 parts, Bauhinia champloni 150-250 parts, prinos-like salacia root 150-250 parts.
Preferably, it is prepared by following raw materials in part by weight proportioning：8750 parts of Pterospermi Heterophyllis of small 1250 parts, 55 ° white wine of suckling mouse
200 parts, 200 parts of Bauhinia champloni, 200 parts of prinos-like salacia root.
The small suckling mouse, it is the firm small suckling mouse for being born and not opening eyes and not becoming mildewed.Germ content is extremely low in small suckling mouse body, and its body
Vivo protein can be gradually decomposed into amino acid, be subsequently solubolized in wine.
The Pterospermi Heterophylli, it is that section is cleaned into the root of Sterculiaceae plant pterospermum heterophyllum Hance, dries to obtain after being evaporated.Half maple
Lotus is the root or stem branch of Sterculiaceae plant pterospermum heterophyllum Hance, is compared with stem branch, and the flavour of a drug of root are denseer, bitter also slightly heavy.
The Bauhinia champloni, it is that the root of Bauhinia champloni is cleaned into section, dries to obtain after being evaporated.The dispelling wind and removing obstruction in the meridians of the root of Bauhinia champloni
Effect imitates stem, the leaf for being better than Bauhinia champloni.
The method for preparing the mouse wine, comprises the following steps：
(1) small suckling mouse, white wine, Pterospermi Heterophylli, Bauhinia champloni, prinos-like salacia root are weighed by weight ratio；
(2) dry, be put into bottle after small suckling mouse is cleaned with clear water；
(3) dried after rinsing Pterospermi Heterophylli, Bauhinia champloni, prinos-like salacia root, remove floating dust, separately packaged and be put into screen pack bag
In bottle, raw material is avoided to influence each other；
(4) white wine is poured into bottle, closed the lid, sealed, closed immersion 12-24 months, treat beneficiating ingredient in raw material
Fully leach；
(5) by the filtering of soaked mouse wine, sterilizing, packing, produce.
The sealing, sealed using the method for fluid-tight.Liquid seal method can be good isolation air, and do not influence to arrange
Gas, and avoid pressure differential excessive.
The sealing, sealed using diaphragm seal.Diaphragm seal sealing is simple and easy to do, cost is cheap.
The step (4), lucifuge and control temperature to be not higher than 35 DEG C in closed immersion process, avoid wherein beneficial into
Decompose.
It is that wine liquid is irradiated using 254nm ultraviolet lights that the sterilizing, which is, exposure dose of the ultraviolet light on wine liquid surface
For 30-300mWmin/cm2, wine liquid thickness is 2cm.Sterilized using ultraviolet light, it is possible to prevente effectively from conventional high temperature kills
Destruction of the bacterium to beneficiating ingredient in wine liquid.
Small suckling mouse：It is sweet, mild-natured, returns spleen, stomach, there is qi-restoratives to disappear infantile malnutrition due to digestive disturbances or intestinalparasites, the effect of detoxification sore treatment.It is thin thin for consumptive disease,
Infantile malnutrition, burn and scald, traumatism and bleeding, pernio, traumatic injury.And after rice wine immersion of the suckling mouse through high concentration, its body
Internal protein can be gradually decomposed into amino acid, be subsequently solubolized in alcohol.
White wine：It is sweet, bitter, pungent, it is warm-natured.The thoughts of returning home, liver, lung, stomach.Promoting blood circulation, row medicine gesture.For chill numbness pain, tendon and vessel
Contraction is anxious, and the obstruction of qi in the chest is pained, coldness and pain in the epigastrium.
Pterospermi Heterophylli：For the root or stem branch of Sterculiaceae plant pterospermum heterophyllum Hance.It is sweet, it is warm-natured.Wind-damp dispelling, relaxing tendons and activating collaterals.With
In rheumatic arthritis, rheumatoid arthritis, lumbar muscle strain, chronic lumbocrural pain, hemiplegia, traumatic injury, bruise；External application
Control bleeding on knife.
Bauhinia champloni：Bauhinia champloni is a kind of flowering plant of pulse family Caesalpinoidea Bauhinia.There is dispelling wind and eliminating dampness, promoting blood circulation stops
Bitterly, the effect of invigorating the spleen qi-regulating.For rheumatic arthritis, waist-leg pain, traumatic injury, stomachache, infantile malnutrition.
Prinos-like salacia root：For five layers of imperial root of Hippocrateaceae plant.Puckery, it is warm-natured.Return liver and kidney channel.Dispelling wind and eliminating dampness, work of stimulating the menstrual flow
Blood.For rheumatism bi Zheng, hemostagnant lumbago.
After rice wine immersion of the suckling mouse through high concentration, its body internal protein can be gradually decomposed into amino acid, be subsequently solubolized in
In alcohol.As the protein of the first nutritional factors in body, its effect in food nutrition be it will be apparent that but it
Can not directly it be utilized in human body, but by becoming what is be utilized after amino acid small molecule.If amino acid is directly dissolved in
In wine, it is easier to absorbed by drinking person, so as to produce the effect of enhancing immunity of organisms.In addition, rice wine inherently possesses work
Blood effect, the pure grain wine of height can more make small suckling mouse and auxiliary the effective elements of the medicine be completely dissolved release, three's collective effect, can make
Drinking person is energetic, in the green.Often had a delicate constitution when puerpera is confined in childbirth, vim and vigour are not smooth, and one should be had by drinking such tonic wine
Fixed tonic effect.
Compared with prior art, the technique effect of the invention is embodied in：
The mouse wine of the present invention, give full play to nascent small suckling mouse qi-restoratives and disappear infantile malnutrition due to digestive disturbances or intestinalparasites, the effect of detoxification sore treatment, and make small breast of coming into being
The gradual breaks down into amino acids of protein in mouse body is simultaneously dissolved in wine, reaches tonic effect, then is aided with Pterospermi Heterophylli clearing damp dehumidifying, living
Blood dredging collateral；Bauhinia champloni dispelling wind and eliminating dampness, proceeds blood cycle；Prinos-like salacia root dispelling wind and eliminating dampness, the effect to restore menstrual flow and invigorate blood circulation, by small suckling mouse and half maple
The property of medicine of the complementary medicinal material such as lotus, Bauhinia champloni, prinos-like salacia root is combined together, make mouse wine in traumatic injury, relaxing tendons and activating collaterals side
Face effect is strengthened, and not overstimulation, and amino acid content is higher than common mouse wine, has finally given a kind of amino acid and has contained
Amount is high, and the property of medicine is moderate, the good mouse wine for the treatment of traumatic injury, relaxing tendons and activating collaterals effect.
Embodiment
Limited with reference to specific embodiment technical scheme is further, but claimed
Scope is not only limited to made description.
Embodiment 1
A kind of mouse wine, is prepared via a method which：
(1) small suckling mouse 1250g, 55 ° of white wine 8750g. Pterospermi Heterophyllis 200g, Bauhinia champloni 200g, prinos-like salacia root 200g are weighed；
(2) dry, be put into bottle after small suckling mouse is cleaned with clear water；
(3) dried after rinsing Pterospermi Heterophylli, Bauhinia champloni, prinos-like salacia root, remove floating dust, separately packaged and be put into screen pack bag
In bottle, raw material is avoided to influence each other；
(4) white wine is poured into bottle, closed the lid, fluid-tight, closed immersion 18 months, lucifuge in closed immersion process,
And control temperature to be not higher than 35 DEG C, treat that beneficiating ingredient fully leaches in raw material；
(5) soaked mouse wine is filtered, wine liquid is irradiated using 254nm ultraviolet lights, ultraviolet light is in wine liquid table
The exposure dose in face is 160mWmin/cm2, wine liquid thickness is 2cm, packing, is produced.
The small suckling mouse, it is the firm small suckling mouse for being born and not opening eyes and not becoming mildewed.
The Pterospermi Heterophylli, it is that section is cleaned into the root of Sterculiaceae plant pterospermum heterophyllum Hance, dries to obtain after being evaporated.
Embodiment 2
A kind of mouse wine, is prepared via a method which：
(1) small suckling mouse 1000g, 50 ° of white wine 7500g, Pterospermi Heterophylli 150g, Bauhinia champloni 150g, prinos-like salacia root 150g are weighed；
(2) dry, be put into bottle after small suckling mouse is cleaned with clear water；
(3) dried after rinsing Pterospermi Heterophylli, Bauhinia champloni, prinos-like salacia root, remove floating dust, separately packaged and be put into screen pack bag
In bottle, raw material is avoided to influence each other；
(4) white wine is poured into bottle, closed the lid, fluid-tight, closed immersion 12 months, lucifuge in closed immersion process,
And control temperature to be not higher than 35 DEG C, treat that beneficiating ingredient fully leaches in raw material；
(5) soaked mouse wine is filtered, wine liquid is irradiated using 254nm ultraviolet lights, ultraviolet light is in wine liquid table
The exposure dose in face is 30mWmin/cm2, wine liquid thickness is 2cm, packing, is produced.
The small suckling mouse, it is the firm small suckling mouse for being born and not opening eyes and not becoming mildewed.
The Pterospermi Heterophylli, it is that section is cleaned into the root of Sterculiaceae plant pterospermum heterophyllum Hance, dries to obtain after being evaporated.
Embodiment 3
A kind of mouse wine, is prepared via a method which：
(1) small suckling mouse 1500g, 60 ° of white wine 10000g, Pterospermi Heterophylli 250g, Bauhinia champloni 250g, prinos-like salacia root 250g are weighed；
(2) dry, be put into bottle after small suckling mouse is cleaned with clear water；
(3) dried after rinsing Pterospermi Heterophylli, Bauhinia champloni, prinos-like salacia root, remove floating dust, separately packaged and be put into screen pack bag
In bottle, raw material is avoided to influence each other；
(4) white wine is poured into bottle, closed the lid, fluid-tight, closed immersion 24 months, lucifuge in closed immersion process,
And control temperature to be not higher than 35 DEG C, treat that beneficiating ingredient fully leaches in raw material；
(5) soaked mouse wine is filtered, wine liquid is irradiated using 254nm ultraviolet lights, ultraviolet light is in wine liquid table
The exposure dose in face is 300mWmin/cm2, wine liquid thickness is 2cm, packing, is produced.
The small suckling mouse, it is the firm small suckling mouse for being born and not opening eyes and not becoming mildewed.
The Pterospermi Heterophylli, it is that section is cleaned into the root of Sterculiaceae plant pterospermum heterophyllum Hance, dries to obtain after being evaporated.
Embodiment 4
A kind of mouse wine, is prepared via a method which：
(1) small suckling mouse 1250g, 55 ° of white wine 8750g. Pterospermi Heterophyllis 200g, Bauhinia champloni 200g, prinos-like salacia root 200g are weighed；
(2) dry, be put into bottle after small suckling mouse is cleaned with clear water；
(3) dried after rinsing Pterospermi Heterophylli, Bauhinia champloni, prinos-like salacia root, remove floating dust, separately packaged and be put into screen pack bag
In bottle, raw material is avoided to influence each other；
(4) white wine is poured into bottle, closed the lid, sealed with diaphragm seal, closed immersion 18 months, closed immersion process
Middle lucifuge and control temperature be not higher than 35 DEG C, treat that beneficiating ingredient fully leaches in raw material；
(5) soaked mouse wine is filtered, wine liquid is irradiated using 254nm ultraviolet lights, ultraviolet light is in wine liquid table
The exposure dose in face is 160mWmin/cm2, wine liquid thickness is 2cm, packing, is produced.
The small suckling mouse, it is the firm small suckling mouse for being born and not opening eyes and not becoming mildewed.
The Pterospermi Heterophylli, it is that section is cleaned into the root of Sterculiaceae plant pterospermum heterophyllum Hance, dries to obtain after being evaporated.
Embodiment 5
A kind of mouse wine, is prepared via a method which：
(1) small suckling mouse 1250g, 55 ° of white wine 8750g. Pterospermi Heterophyllis 200g, Bauhinia champloni 200g, prinos-like salacia root 200g are weighed；
(2) dry, be put into bottle after small suckling mouse is cleaned with clear water；
(3) dried after rinsing Pterospermi Heterophylli, Bauhinia champloni, prinos-like salacia root, remove floating dust, separately packaged and be put into screen pack bag
In bottle, raw material is avoided to influence each other；
(4) white wine is poured into bottle, closed the lid, fluid-tight, closed immersion 18 months, lucifuge in closed immersion process,
And control temperature to be not higher than 35 DEG C, treat that beneficiating ingredient fully leaches in raw material；
(5) soaked mouse wine is filtered, 15-20min is heated at 75-80 DEG C, packing, is produced.
The small suckling mouse, it is the firm small suckling mouse for being born and not opening eyes and not becoming mildewed.
The Pterospermi Heterophylli, it is that section is cleaned into the root of Sterculiaceae plant pterospermum heterophyllum Hance, dries to obtain after being evaporated.
The sterilization mode of the present embodiment is conventional pasteurize.
Comparative example 1
A kind of mouse wine, is prepared via a method which：
(1) small suckling mouse 1250g is weighed；
(2) dry, be put into bottle after small suckling mouse is cleaned with clear water；
(3) white wine is poured into bottle, closed the lid, fluid-tight, closed immersion 18 months, lucifuge in closed immersion process,
And control temperature to be not higher than 35 DEG C, treat that beneficiating ingredient fully leaches in raw material；
(4) soaked mouse wine is filtered, wine liquid is irradiated using 254nm ultraviolet lights, ultraviolet light is in wine liquid table
The exposure dose in face is 160mWmin/cm2, wine liquid thickness is 2cm, packing, is produced.
The small suckling mouse, it is the firm small suckling mouse for being born and not opening eyes and not becoming mildewed.
Antifatigue measure of merit：
(mouse forced swimming) is tested by exercise tolerance, verifies the antifatigue effect effect of mouse wine of the present invention.
1st, material
1.1 experimental animal
SPF level KM mouse, male and female half and half, 20 ± 2g of body weight.Animal feeding in meet medical experiment animal environment facility will
In the feeding environment asked.Rearing conditions：25 ± 2 DEG C of room temperature, humidity 60 ± 20%.
1.2 test medicine
Mouse wine：The mouse wine being prepared according to embodiment 1-5, the methods described of comparative example 1.
2nd, method and result
Method：
The mouse wine being prepared according to embodiment 1-5 and the methods described of comparative example 1, respectively weighs 2.25g, is matched somebody with somebody with distilled water
To 150ml, embodiment 1-5 and the mouse wine dilution of comparative example 1 are obtained.
Mouse is divided into 6 groups at random, every group 10, the 1st group to the 5th group mouse wine dilution for giving embodiment 1-5 respectively,
The 5th group of mouse wine dilution to comparative example 1, the 7th group is blank control group, gives isometric distilled water, and every group fills daily
Stomach 1 time, gavage amount are 0.2ml/10g, continuous gavage 30 days.
After testing last dose 30min, mouse is put in swimming trunk, depth of water 40cm, 25 DEG C of water temperature, rat-tail root load
The sheet lead of 5% body weight, record mouse swimming started to the time (power exhausts the time) to sink under water, as mouse swimming time
As a result：
Contrast is understood, after orally administration mouse embodiment 15, the medicine of comparative example 1, compared with blank control group, is substantially prolonged
The long mice burden swimming time.The positive effect of mouse wine group of the present invention is better than and 1 group of comparative example.To sum up, mouse of the invention
Wine is better than existing mouse wine in antifatigue aspect positive effect.
Clinical test arranges：
Mr. Li, female, 53 years old, with rheumatoid arthritis, drink the mouse wine 20ml of the gained of embodiment 1 daily, 3 weeks
Pain relief afterwards, pain almost disappears after 5 weeks.
It is deep certain, man, 58 years old, with rheumatoid arthritis, the mouse wine 40ml of the gained of embodiment 1 is drunk daily, after 6 weeks
Pain relief, pain almost disappears after 9 weeks.
Thunder, female, 46 years old, with lumbar muscle strain, the mouse wine 20ml of the gained of embodiment 1 is drunk daily, pain subtracts after 4 weeks
Gently, pain almost disappears after 6 weeks.
It is blue so-and-so, man, 57 years old, with long-term waist and leg ache, the mouse wine 40ml of the gained of embodiment 1 is drunk daily, after 4 weeks
Pain relief, pain almost disappears after 12 weeks.
To sum up, illustrate that mouse wine treatment traumatic injury, the relaxing tendons and activating collaterals effect of the present invention are good, can effectively alleviate rheumatic
Arthritis and various muscle, arthralgia and myalgia.
Finally it is pointed out that above example is only the more representational example of the present invention.Obviously, technology of the invention
Scheme is not limited to above-described embodiment, can also there is many deformations.One of ordinary skill in the art can be from disclosed by the invention
All deformations that content is directly exported or associated, are considered as protection scope of the present invention.
Claims (10)
1. a kind of mouse wine, it is characterised in that be prepared by following raw materials in part by weight proportioning：Small suckling mouse 1000-1500 parts,
50-60 ° of white wine 7500-10000 part, Pterospermi Heterophylli 150-250 parts, Bauhinia champloni 150-250 parts, prinos-like salacia root 150-250 parts.
2. mouse wine according to claim 1, it is characterised in that be prepared by following raw materials in part by weight proportioning：Small breast
Mouse 1250 parts, 55 ° 8750 parts of white wine, 200 parts of Pterospermi Heterophyllis, 200 parts of Bauhinia champloni, 200 parts of prinos-like salacia roots.
3. mouse wine according to claim 1 or 2, it is characterised in that the small suckling mouse, be just to be born not opening eyes not become mildewed
Small suckling mouse.
4. mouse wine according to claim 1 or 2, it is characterised in that the Pterospermi Heterophylli, be by the different leaf wing of Sterculiaceae plant
Section is cleaned in the root of sub- wood, dries to obtain after being evaporated.
5. mouse wine according to claim 1 or 2, it is characterised in that the Bauhinia champloni, be to clean the root of Bauhinia champloni to cut
Piece, dry to obtain after being evaporated.
6. a kind of preparation method for preparing the mouse wine of claim 1 or 2, it is characterised in that comprise the following steps：
(1) small suckling mouse, white wine, Pterospermi Heterophylli, Bauhinia champloni, prinos-like salacia root are weighed by weight ratio；
(2) dry, be put into bottle after small suckling mouse is cleaned with clear water；
(3) dried after rinsing Pterospermi Heterophylli, Bauhinia champloni, prinos-like salacia root, separately packaged and be put into bottle with screen pack bag；
(4) white wine is poured into bottle, closed the lid, sealed, closed immersion 12-24 months；
(5) by the filtering of soaked mouse wine, sterilizing, packing, produce.
7. the preparation method of mouse wine according to claim 6, it is characterised in that the sealing, be the side using fluid-tight
Method is sealed.
8. the preparation method of mouse wine according to claim 6, it is characterised in that the sealing, sealed using diaphragm seal
Mouthful.
9. the preparation method of mouse wine according to claim 6, it is characterised in that the step (4), closed immersion process
Middle lucifuge and control temperature be not higher than 35 DEG C.
10. the preparation method of mouse wine according to claim 6, it is characterised in that the sterilizing, be purple using 254nm
Outer light is irradiated to wine liquid, and exposure dose of the ultraviolet light on wine liquid surface is 30-300mWmin/cm2, wine liquid thickness is
2cm。
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| JP2003000211A (en) * | 2001-04-16 | 2003-01-07 | Asahi Soft Drinks Co Ltd | Drink for treatment/prophylaxis of diabetes |
| CN103505662A (en) * | 2013-10-12 | 2014-01-15 | 陈友望 | Baby mouse containing medicinal liquor formula |
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2017
- 2017-12-12 CN CN201711318575.8A patent/CN107854512A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
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