CN107854131B - Multi-element non-invasive testing method and device for human tissue - Google Patents
Multi-element non-invasive testing method and device for human tissue Download PDFInfo
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- CN107854131B CN107854131B CN201711070885.2A CN201711070885A CN107854131B CN 107854131 B CN107854131 B CN 107854131B CN 201711070885 A CN201711070885 A CN 201711070885A CN 107854131 B CN107854131 B CN 107854131B
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Abstract
The invention discloses a human tissue multi-element non-invasive test method and a device thereof, wherein the device comprises a case, a multi-channel analyzer, a control terminal, an output device and a tested body fixing device, wherein the tested body is a human arm, a finger or a human leg tibia, a stepping motor driver, an X-ray generating device, an X-ray detecting and analyzing device, a communication module, a protection device, a semiconductor heat dissipation device and a visual tracking system are arranged in the case, and the X-ray generating device, the X-ray detecting and analyzing device, the protection device, the semiconductor heat dissipation device and the visual tracking system are respectively and electrically connected with the communication module; the communication module, the multi-channel analyzer, the control terminal and the output device are electrically connected in sequence. By arranging the quadrangular frustum pyramid, the protection device, the semiconductor heat dissipation device and the visual tracking system, the bone lead density test data of the human body is more accurate and reliable, a favorable reference is provided for bone lead diagnosis, and a foundation is laid for disease diagnosis by quantitatively analyzing other heavy metal elements in the human body.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a human tissue multi-element noninvasive testing method and a device thereof.
Background
Lead is the only trace element not required by the human body and can cause damage to almost all organs of the human body. It is characterized by affecting the development of intelligence and skeleton development, causing dyspepsia and endocrine disturbance, resulting in anemia, hypertension and arrhythmia, and destroying renal function and immune function. Even if the blood lead level is significantly reduced after the removal from the polluted environment or treatment, the damaged organs and tissues cannot be repaired, which is accompanied by life-long. According to the research of experts, when the blood lead level of children rises by 100 mu g/L, the intelligence quotient of the children is reduced by 6-8 minutes, the height is delayed by 1.3 cm, and the weight is reduced by 2-3 kg. Lead pollution in everyday environments is almost ubiquitous and poses a serious threat to the health of humans, especially children.
At present, the lead density content of human bones can be detected, an isotope radiation source or an X-ray tube can be used for emitting X-rays to interact with atoms of lead elements and other trace elements in the human bones, the energy of characteristic X-rays emitted in the process of de-excitation after the atoms of various elements are excited is different, and the qualitative and quantitative analysis can be sequentially carried out on the lead of the human bones according to the characteristic. The detector for bone lead density of human body utilizes the working principle to analyze the bone lead density content in human body, and the minimum radioactive dose equivalent of the used ray (minimum dose can be less than 1 mu Sv) is equivalent to one percent of the irradiation dose of the conventional X-ray film of human breast, so that the detector is very safe, has no damage to human body measurement, and is widely used in the medical field.
The device and the method are particularly improved, and the device and the method are suitable for the multi-element noninvasive detection of human tissues.
Disclosure of Invention
The invention aims to provide a human tissue multi-element noninvasive test method and a device thereof, which enable the human bone lead density test data to be more accurate and reliable by arranging a quadrangular frustum, a protection device, a semiconductor heat dissipation device and a visual tracking system, provide favorable reference for bone lead diagnosis and lay a foundation for disease diagnosis by quantitatively analyzing other heavy metal elements in a human body.
In order to achieve the purpose, the invention adopts the technical scheme that: the human tissue multi-element noninvasive test device comprises a case, a multi-channel analyzer, a control terminal, output equipment and a tested body fixing device, wherein the tested body is a human arm, a finger or a shin bone of a human leg, a stepping motor driver, an X-ray generating device, an X-ray detecting and analyzing device, a communication module, a protection device, a semiconductor heat dissipation device and a visual tracking system are arranged in the case, and the X-ray generating device, the X-ray detecting and analyzing device, the protection device, the semiconductor heat dissipation device and the visual tracking system are respectively and electrically connected with the communication module; the communication module, the multi-channel analyzer, the control terminal and the output equipment are electrically connected in sequence;
the X-ray generating device comprises a switch circuit, a high-voltage excitation control box, an X-ray tube, a collimator and an optical filter, wherein the switch circuit, the high-voltage excitation control box, the X-ray tube, the collimator and the optical filter are sequentially connected;
the X-ray detection and analysis device comprises a secondary high pressure plate, a digital pulse processor and an X-ray detector which are sequentially connected;
the X-ray tube and the X-ray detector are respectively fixedly arranged on a quadrangular frustum with a groove at the bottom, probes of the X-ray tube and the X-ray detector respectively penetrate through mounting through holes in the side wall of the quadrangular frustum in a direction of 45 degrees with a measured body and extend into the groove, and extension lines of the axes of the probes of the X-ray tube and the X-ray detector are intersected with a measured body mark point at a detection port of the case and used for exciting and receiving characteristic X-rays; a dovetail groove is formed in the outer side of the X-ray tube probe mounting through hole in the side wall of the quadrangular frustum, a mounting plate for fixing the X-ray tube is arranged in the dovetail groove in a sliding mode, U-shaped sliding grooves are symmetrically formed in two edges of the mounting plate along the sliding direction of the dovetail groove, and positioning bolts are arranged in the sliding grooves; an L-shaped positioning plate for mounting an X-ray detector is arranged on the outer side of the X-ray detector probe mounting through hole on the side wall of the quadrangular frustum;
the communication module comprises a communication control panel and a communication box which are connected with each other;
the protection device includes: a voltage transformer, a current transformer and a rotating speed detector; the voltage transformer monitors the voltage of the instrument, the current transformer monitors the current of the instrument, and the rotating speed monitor monitors the rotating speed of a motor in the generator instrument; the voltage, the current or the rotating speed of the motor of the instrument are sent to the control terminal, and when the voltage, the current or the rotating speed of the motor of the instrument is too large, the control terminal judges that the operation of the instrument is in a dangerous state, and timely safety remedial measures can be carried out.
The semiconductor heat dissipation device comprises a semiconductor heat dissipation sheet, a temperature detection unit and a temperature upper limit alarm unit which are sequentially connected; the temperature detection unit is used for detecting the temperature of each component in the case in real time, so that the detection precision is prevented from being influenced and even an instrument is prevented from being damaged due to overhigh temperature; when the temperature detection unit detects that the temperature in the chassis is overhigh, the semiconductor cooling fin is controlled to strengthen the cooling intensity; when the temperature detection unit detects that the temperature in the case reaches the upper limit value, the temperature upper limit alarm unit gives an alarm, and at the moment, the instrument can be properly closed, so that the instrument is prevented from being used for a long time and being out of order.
The visual tracking system is used for calibrating the relative position of a mark point of a detected body and a detection port of the case, and comprises a visual tracker, an identification positioning module and a first pressure sensor arranged at the edge of the detection port; the visual tracker is used for detecting and tracking the position information of the mark points of the detected body; the identification positioning module is used for automatically identifying and positioning the position information of the mark point of the detected body detected by the visual tracker; the first pressure sensor is used for judging whether the detected body is tightly attached to the detection port or not. The relative position of the mark point of the detected body and the detection port is accurately adjusted through a visual tracking system, and the detection precision of the instrument is improved.
The structure of the multichannel analyzer is as follows: the amplifier, the standard linear gate, the wave crest delayer and the ADC are sequentially connected with the SCA and are respectively connected with the standard linear gate and the ADC.
Furthermore, the fixing device of the tested body comprises a fixing bracket, a fixing plate with a concave section and a bottom plate, and an inflating fixing device is arranged on the inner side of the fixing plate; the inflatable fixing device is divided into three parts which are respectively used for abutting against the left side, the right side and the rear side of the measured body, and a second pressure sensor is arranged on the surface of the contact side of the inflatable fixing device and the measured body; the bottom plate can vertically move up and down along the fixed support, and the surface of the bottom plate is provided with a cotton pad. The distance between the detection point and the detection port is accurately adjusted under the condition of ensuring the comfort degree of the detected body, so that the conditions of data abnormity and the like caused by interference on bone lead density detection of a human body due to movement or shaking of legs are prevented, and the bone lead density test data is accurate and reliable.
Furthermore, the bottom of the quadrangular frustum is positioned outside the groove and is sequentially provided with a sealing ring and a buckle, and the inner side of the case is positioned outside the detection port and is provided with a card slot matched with the buckle. The sealing ring is arranged around the center of the detection port, can shield scattered X-ray beams, and effectively avoids X-ray radiation at the detection port; play the positioning action through buckle and card slot cooperation, can install the pyramid platform on the detector fast, improved the accuracy of packaging efficiency and instrument detection data greatly.
Furthermore, the testing device also comprises an alarm prompting module, and the alarm prompting module is used for detecting system abnormity, alarming, detection preparation and detection completion reminding.
Furthermore, a plurality of working state indicator lamps are arranged on the case, each working state indicator lamp comprises an executable indicator lamp, a executing indicator lamp, an alarm indicator lamp and a fault indicator lamp, and the working state of the instrument is visually observed through the working state indicator lamps.
Further, the control terminal is a computer, and the communication module connected with the computer is a wireless communication module. Through wireless communication module, can realize the long-range real time control of instrument, need not to place computer and detecting instrument in same space during the detection, be favorable to the staff's of long-term operation instrument healthy.
Furthermore, the control terminal is a display operation device arranged on the chassis, the display operation device comprises a processing module, a control circuit and a control panel, and the processing module is respectively connected with the control circuit and the control panel; the control panel includes a display screen and a plurality of control buttons. The control terminal is directly arranged on the case without being specially equipped with a computer, so that the material consumption is reduced, and the convenience of using the instrument is improved. The display operation device further comprises a touch screen.
A human tissue multielement non-invasive test method comprises the following steps: 1) fixing the detected body by using the detected body fixing device, and enabling the mark point of the detected body to be closely attached to and correspond to the detection port by matching with a visual tracking system; 2) selecting measurement parameters including digital setting of high voltage, current and measurement duration of the X-ray tube by the control terminal, and starting measurement; 3) the control terminal sends out an instruction, and the instruction sequentially passes through the communication module and the high-voltage excitation control box to the X-ray tube; the X-ray tube emits X-rays which are emitted through the detection port and irradiate the detected body for a time of 120-500s, so that the detected body element is excited to generate fluorescence, the X-ray fluorescence is processed by the X-ray detection and analysis device and then converted into an electric signal, and the electric signal is transmitted to the multi-channel analyzer through the communication module to be analyzed and then returns to the control terminal to be calculated to obtain the density value of the detected body element; 4) and outputting the test condition by the output device.
Compared with the prior art, the invention has the beneficial effects that: 1. according to the invention, the X-ray probe and the X-ray detector probe are accurately controlled to be fixed at an angle of 45 degrees relative to the measured surface through the quadrangular frustum, so that the equipment assembly efficiency and the accuracy of a detection result are improved; by arranging the protection device, the voltage and the current of the instrument or the rotating speed of the motor are prevented from being overlarge, so that the instrument can normally operate; the detection precision and even the damage of an instrument are prevented from being influenced by overhigh temperature through the semiconductor heat dissipation device; the position of the fixed seat of the tested body is adjusted through the visual tracker, so that the automatic identification and positioning of the position information of the mark point and the detection port of the tested body are realized, the first pressure sensor judges whether the tested body is attached to the detection port, the detection precision of an instrument is improved, and the lead density test data of the bone of the human body are more accurate and reliable; 2. the invention has simple operation and convenient use, reduces the working difficulty of testers, has low production cost and easy maintenance, is suitable for the rapid, noninvasive and quantitative detection of heavy metal elements in human tissues such As Pb, Cd, Hg, Cr, As, Ca, Zn, Sr and the like, can obtain the information of the nutritional status, the bone status and trace elements (Sr) influencing the occurrence of cardiovascular diseases of human bodies by measuring Ca, Zn and Sr in the tibia, and lays a foundation for diagnosing and treating the diseases; 3. the device for measuring the human body bone lead density adopts an X-ray tube to excite bone lead, and a novel Silicon Drift Detector (SDD) is used for receiving Pb characteristic signals, so that minimum detection lower limit MDC (modified discrete cosine transform) can be realized 1 mu g/g bone, and meets the analysis requirement of lead poisoning people. Therefore, the product not only exceeds the analysis sensitivity of foreign laboratories, but also achieves the aims of miniaturization, simple structure and digital type.
Drawings
FIG. 1 is a schematic structural diagram of a multi-element noninvasive testing device for human tissue according to the invention;
FIG. 2 is a block diagram of the apparatus for non-invasive testing of multiple elements of human tissue according to the present invention;
FIG. 3 is a schematic structural diagram of the X-ray tube and the X-ray detector of the present invention mounted on a quadrangular frustum;
FIG. 4 is a schematic top view of a quadrangular frustum;
FIG. 5 is a schematic bottom view of a quadrangular frustum;
FIG. 6 is a schematic view of a dovetail groove configuration for mounting an X-ray tube;
FIG. 7 is a schematic view of a mounting plate configuration for mounting an X-ray tube;
FIG. 8 is a schematic cross-sectional view of a holder for a subject;
in the figure: 1. a probe; 2.1, a digital pulse processor; 2.2, an X-ray detector; 3. a secondary high-voltage plate; 4. a communication control panel; 5. a communication box; 6. a switching circuit; 7. a high voltage excitation control box; 8. an X-ray tube; 9. a quadrangular frustum pyramid; 900. a seal ring; 901. buckling; 902. mounting a through hole; 903. a dovetail groove; 904. mounting a plate; 905. a chute; 906. positioning the bolt; 907. an L-shaped positioning plate; 10. a control terminal; 11. an output device; 12. a semiconductor heat sink; 120. a semiconductor heat sink; 121. a temperature detection unit; 122. an upper temperature limit alarm unit; 13. a visual tracking system; 130. a visual tracker; 131. identifying a positioning module; 132. a first pressure sensor; 14. a multi-channel analyzer; 15. a groove; 16. a chassis; 17. a subject fixing device; 170. fixing a bracket; 171. a fixing plate; 172. a base plate; 173. an inflation fixing device; 174. a second pressure sensor; 175. a cotton pad; 18. a stepper motor driver; 19. a protection device; 190. a voltage transformer; 191. a current transformer; 192. a rotation speed detector; 20. an alarm prompt module; 21. and a working state indicator lamp.
Detailed Description
The technical solutions of the present invention will be described clearly and completely with reference to the accompanying drawings, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example one
As shown in fig. 1-7, the multi-element noninvasive testing device for human tissue comprises a case 16, a multichannel analyzer 14, a control terminal 10, an output device 11, and a tested body fixing device 17, wherein a stepping motor driver 18, an X-ray generating device, an X-ray detecting and analyzing device, a communication module, a protection device 19, a semiconductor heat dissipation device 12, and a visual tracking system 13 are arranged in the case 16, and the X-ray generating device, the X-ray detecting and analyzing device, the protection device 19, the semiconductor heat dissipation device 12, and the visual tracking system 13 are respectively electrically connected to the communication module; the communication module, the multi-channel analyzer 14, the control terminal 10 and the output device 11 are electrically connected in sequence; the X-ray generating device comprises a switch circuit 6, a high-voltage excitation control box 7, an X-ray tube 8, a collimator and a filter, wherein the collimator and the filter are sequentially connected; the X-ray detection and analysis device comprises a secondary high pressure plate 3, a digital pulse processor 2.1 and an X-ray detector 2.2 which are connected in sequence; the X-ray tube 8 and the X-ray detector 2.2 are respectively fixedly arranged on a quadrangular frustum 9 with a groove 15 at the bottom, probes 1 of the X-ray tube 8 and the X-ray detector 2.2 respectively penetrate through mounting through holes 902 on the side wall of the quadrangular frustum 9 in a direction of 45 degrees with a detected body and extend into the groove 15, and axial extension lines of the probes 1 of the X-ray tube 8 and the X-ray detector 2.2 are intersected at a detected body mark point at a detection port of the case 16 and used for exciting and receiving characteristic X-rays; a dovetail groove 903 is formed in the outer side of an installation through hole 902 of the probe 1 of the X-ray tube 8 on the side wall of the quadrangular frustum 9, an installation plate 904 for fixing the X-ray tube 8 is arranged in the dovetail groove 903 in a sliding mode, two edges of the installation plate 904 in the sliding direction of the dovetail groove 903 are symmetrically provided with U-shaped sliding grooves 905, and positioning bolts 906 are arranged in the sliding grooves 905; an L-shaped positioning plate 907 for mounting the X-ray detector 2.2 is arranged on the side wall of the quadrangular frustum 9 and outside the mounting through hole 902 of the X-ray detector 2.2 probe 1; the communication module comprises a communication control panel 4 and a communication box 5 which are connected with each other; the protection device 19 includes: a voltage transformer 190, a current transformer 191 and a rotating speed detector 192; the semiconductor heat sink 12 comprises a semiconductor heat sink 120, a temperature detection unit 121 and an upper temperature limit alarm unit 122 which are connected in sequence; the vision tracking system 13 is used for calibrating the relative position of the mark point of the detected object and the detection port of the case 16, and comprises a vision tracker 130, an identification positioning module 131 and a first pressure sensor 132 arranged at the edge of the detection port.
The control terminal 10 is a computer.
The structure of the multichannel analyzer 14 is: the amplifier, the standard linear gate, the wave crest delayer and the ADC are sequentially connected with the SCA and are respectively connected with the standard linear gate and the ADC.
The measured body fixing device 17 is an existing leg support and is specially used for detecting the content of lead in the tibia bone.
The bottom of the quadrangular frustum 9 is positioned outside the groove 15 and is sequentially provided with a sealing ring 900 and a buckle 901, and the inner side of the case 16 is positioned outside the detection port and is provided with a card slot matched with the buckle.
The testing device further comprises an alarm prompt module 20, wherein the alarm prompt module 20 is used for detecting system abnormity, alarming, detection preparation and detection completion reminding.
The case 16 is provided with a plurality of working state indicator lamps 21, the working state indicator lamps 21 comprise an executable indicator lamp, a executing indicator lamp, an alarm indicator lamp and a fault indicator lamp, and the working state of the instrument is observed visually through the working state indicator lamps 21.
The invention is suitable for quantitative detection of multiple elements of human arms, fingers or shin bones of human legs.
Example two
As shown in fig. 8, the multi-element noninvasive testing device for human tissue only differs from the first embodiment in that: the measured body fixing device 17 comprises a fixing bracket 170, a fixing plate 171 with a concave section and a bottom plate 172, and an inflation fixing device 173 is arranged on the inner side of the fixing plate 171; the inflatable fixing device 173 is divided into three parts, which are respectively used for abutting against the left side, the right side and the rear side of the measured body, and the surface of the contact side of the inflatable fixing device 173 and the measured body is provided with a second pressure sensor 174; the bottom plate 172 can vertically move up and down along the fixing bracket 170, and a cotton pad 175 is arranged on the surface of the bottom plate 172. The distance between the detection point and the detection port is accurately adjusted under the condition of ensuring the comfort degree of the detected body, so that the conditions of data abnormity and the like caused by interference on bone lead density detection of a human body due to movement or shaking of legs are prevented, and the bone lead density test data is accurate and reliable.
EXAMPLE III
The multi-element non-invasive testing device for human tissues only differs from the embodiment in that: the control terminal 10 is a computer, and the communication module connected with the computer is a wireless communication module. Through wireless communication module, can realize the long-range real time control of instrument, need not to place computer and detecting instrument in same space during the detection, be favorable to the staff's of long-term operation instrument healthy.
Example four
The multi-element non-invasive testing device for human tissues only differs from the embodiment in that: the control terminal 10 is a display operation device arranged on the chassis 16, the display operation device includes a processing module, a control circuit and a control panel, and the processing module is respectively connected with the control circuit and the control panel; the control panel includes a display screen and a plurality of control buttons. The control terminal 10 is directly arranged on the case 16 without a special computer, thereby reducing the consumables and improving the convenience of the instrument. The display operation device further comprises a touch screen.
The testing method of the human tissue multielement noninvasive testing device comprises the following steps: 1) the tested body is fixed by the tested body fixing device 17, and the mark point of the tested body is closely corresponding to the detection port by matching with a visual tracking system; 2) according to the condition of the detected body and the element to be detected, the control terminal 10 sets the measurement parameters including the high voltage, the current and the measurement duration of the digital setting X-ray tube, and starts to measure; 3) the control terminal 10 sends out an instruction which sequentially passes through the communication module and the high-voltage excitation control box 7 to the X-ray tube 8; the X-ray tube 8 emits X-rays which are emitted through the detection port and irradiate the detected body for a time of 120-500s (when the test element is Pb, the test time is 300s), so that the electronic energy level in the detected element (Pb, Cd, Hg, Cr, As, Ca, Zn, Sr and the like) in the tissue is changed, characteristic X-ray fluorescence corresponding to the corresponding element is released, the X-ray fluorescence is converted into an electric signal after being processed by the X-ray detection and analysis device, the electric signal is transmitted to the multi-channel analyzer 14 through the communication module and then returns to the control terminal 10 to calculate the element density value of the detected body; 4) the test case is output by the output device 11.
Application example one
Testing the human tibia as above: the tested objects are students, employees, teachers, workers, high-class enterprises and the like which are not confirmed to be seriously polluted by lead, the ages are 18-22, 30-40 and 40-70, and more than 30-40 years are taken in three periods, wherein more than 30-40 men (m) are taken.
By taking the lead poisoning high standard (children poisoning standard) as a reference, the number of people with lead content values of each section of bone is distributed as follows:
the minimum value dmin of the bone lead content is 2.78ppm, and the maximum value d max 163.22ppm.
In conclusion, the device is integrally designed, stable in performance, reliable in operation and high in cost performance; simple operation, short measuring time and high analysis sensitivity.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (9)
1. The human tissue multi-element noninvasive test device comprises a case, a multi-channel analyzer, a control terminal, output equipment and a tested body fixing device, wherein the tested body is a human arm, a finger or a shin bone of a human leg, a stepping motor driver, an X-ray generating device, an X-ray detecting and analyzing device, a communication module, a protection device, a semiconductor heat dissipation device and a visual tracking system are arranged in the case, and the X-ray generating device, the X-ray detecting and analyzing device, the protection device, the semiconductor heat dissipation device and the visual tracking system are respectively and electrically connected with the communication module; the communication module, the multi-channel analyzer, the control terminal and the output equipment are electrically connected in sequence;
the X-ray generating device comprises a switch circuit, a high-voltage excitation control box, an X-ray tube, a collimator and an optical filter, wherein the switch circuit, the high-voltage excitation control box, the X-ray tube, the collimator and the optical filter are sequentially connected;
the X-ray detection and analysis device comprises a secondary high pressure plate, a digital pulse processor and an X-ray detector which are sequentially connected;
the X-ray tube and the X-ray detector are respectively fixedly arranged on a quadrangular frustum with a groove at the bottom, probes of the X-ray tube and the X-ray detector respectively penetrate through mounting through holes in the side wall of the quadrangular frustum in a direction of 45 degrees with a measured body and extend into the groove, and extension lines of the axes of the probes of the X-ray tube and the X-ray detector are intersected with a measured body mark point at a detection port of the case and used for exciting and receiving characteristic X-rays; a dovetail groove is formed in the outer side of the X-ray tube probe mounting through hole in the side wall of the quadrangular frustum, a mounting plate for fixing the X-ray tube is arranged in the dovetail groove in a sliding mode, U-shaped sliding grooves are symmetrically formed in two edges of the mounting plate along the sliding direction of the dovetail groove, and positioning bolts are arranged in the sliding grooves; an L-shaped positioning plate for mounting an X-ray detector is arranged on the outer side of the X-ray detector probe mounting through hole on the side wall of the quadrangular frustum;
the communication module comprises a communication control panel and a communication box which are connected with each other;
the protection device includes: a voltage transformer, a current transformer and a rotating speed detector;
the semiconductor heat dissipation device comprises a semiconductor heat dissipation sheet, a temperature detection unit and a temperature upper limit alarm unit which are sequentially connected;
the visual tracking system is used for calibrating the relative position of a mark point of a detected body and a detection port of the case, and comprises a visual tracker, an identification positioning module and a first pressure sensor arranged at the edge of the detection port; the visual tracker is used for detecting and tracking the position information of the mark points of the detected body; the identification positioning module is used for automatically identifying and positioning the position information of the mark point of the detected body detected by the visual tracker; the first pressure sensor is used for judging whether the detected body is tightly attached to the detection port or not.
2. The device for non-invasive measurement of multiple elements in human tissue according to claim 1, wherein the device for fixing the measured object comprises a fixing bracket, a fixing plate with a concave section and a bottom plate, and an inflatable fixing device is arranged inside the fixing plate; the inflatable fixing device is divided into three parts which are respectively used for abutting against the left side, the right side and the rear side of the measured body, and a second pressure sensor is arranged on the surface of the contact side of the inflatable fixing device and the measured body; the bottom plate can vertically move up and down along the fixed support, and the surface of the bottom plate is provided with a cotton pad.
3. The device for multielement non-invasive testing of human tissue as claimed in claim 1, wherein a sealing ring and a buckle are sequentially arranged outside the groove at the bottom of the quadrangular frustum, and a card slot matched with the buckle is arranged outside the detection port at the inner side of the case.
4. The device for non-invasive testing of multiple elements in human tissue according to claim 1, further comprising an alarm prompt module for alarming abnormality, readiness for testing and reminding completion of testing.
5. The device for non-invasive measurement of multiple elements in human tissue according to claim 1, wherein a plurality of operation status indicators are installed on the housing, and the operation status indicators include an executable indicator, an executing indicator, an alarm indicator and a fault indicator.
6. The device for non-invasive measurement of multiple elements in human tissue according to claim 1, wherein said control terminal is a computer and said communication module connected to said computer is a wireless communication module.
7. The multi-element noninvasive testing device for human tissue of claim 1, wherein the control terminal is a display operation device disposed on a chassis, the display operation device comprises a processing module, a control circuit and a control panel, the processing module is respectively connected with the control circuit and the control panel; the control panel includes a display screen and a plurality of control buttons.
8. The device for non-invasive measurement of multiple elements in human tissue according to claim 7, wherein said display operation device further comprises a touch screen.
9. The method for noninvasive measurement of multiple elements in human tissue according to any one of claims 1-8, wherein 1) the subject is fixed by the subject fixing device, and the marking point of the subject is closely corresponding to the detection port by cooperating with a visual tracking system; 2) selecting measurement parameters including digital setting of high voltage, current and measurement duration of the X-ray tube by the control terminal, and starting measurement; 3) the control terminal sends out an instruction, and the instruction sequentially passes through the communication module and the high-voltage excitation control box to the X-ray tube; the X-ray tube emits X-rays which are emitted through the detection port and irradiate the detected body for a time of 120-500s, so that the detected body element is excited to generate fluorescence, the X-ray fluorescence is processed by the X-ray detection and analysis device and then converted into an electric signal, and the electric signal is transmitted to the multi-channel analyzer through the communication module to be analyzed and then returns to the control terminal to be calculated to obtain the density value of the detected body element; 4) and outputting the test condition by the output device.
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| CN2465181Y (en) * | 2001-02-27 | 2001-12-12 | 吕尤焱 | Desk type bone age and bone density measurer |
| CN100369583C (en) * | 2005-06-29 | 2008-02-20 | 王海婴 | Non-traumatic method and device for measuring lead density of phalanges in human body |
| CN201083700Y (en) * | 2007-08-30 | 2008-07-09 | 沈阳飞机工业（集团）有限公司 | Circular arc weldment X ray radiography universal vehicle |
| CN201189181Y (en) * | 2008-05-08 | 2009-02-04 | 王海婴 | No-wound human cannon-bone lead content measuring device using polarization X-ray beam |
| CN201529126U (en) * | 2009-04-22 | 2010-07-21 | 王海婴 | Noninvasive human body bone lead content measuring device based on radioisotope sources |
| CN203619571U (en) * | 2013-07-25 | 2014-06-04 | 奥美之路(北京)技术顾问有限公司 | Split type bone age machine |
| CN203824909U (en) * | 2014-05-13 | 2014-09-10 | 王海婴 | Multi-element in-vivo in-situ noninvasive analyzer for human tissue |
| CN204092005U (en) * | 2014-08-15 | 2015-01-14 | 北京鑫东华腾体育器械有限公司 | Human body stone age bone density tester |
| CN205411194U (en) * | 2015-11-04 | 2016-08-03 | 武汉市江汉美思科技发展有限公司 | Three -dimensional mobile device of plumbous density detector of human bone |
| CN205458732U (en) * | 2016-01-29 | 2016-08-17 | 武汉市江汉美思科技发展有限公司 | Plumbous density detector constant temperature environment holding device of human bone |
| CN206044644U (en) * | 2016-07-01 | 2017-03-29 | 中国人民解放军第四军医大学 | A kind of device of measurement bone lead content |
| CN209863851U (en) * | 2017-11-03 | 2019-12-31 | 武汉瑞博恩科技发展有限公司 | Multi-element non-invasive detection system for living tissue |
| CN209252896U (en) * | 2017-11-03 | 2019-08-16 | 武汉瑞博恩科技发展有限公司 | Bone Lead density tester with vision tracking and positioning function |
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