CN107850524B - 确定样品扩散特性的方法和装置 - Google Patents

确定样品扩散特性的方法和装置 Download PDF

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CN107850524B
CN107850524B CN201680040098.0A CN201680040098A CN107850524B CN 107850524 B CN107850524 B CN 107850524B CN 201680040098 A CN201680040098 A CN 201680040098A CN 107850524 B CN107850524 B CN 107850524B
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concentration
solute
taylorgram
taylor
solvent
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CN107850524A (zh
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奥克萨纳·巴克·尼·莱什奇申
赛伊·拉通德-达达
雷切尔·博特
卡尔·汉普顿
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Malvern Panalytical Ltd
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Malvern Instruments Ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/06Investigating concentration of particle suspensions
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • G01N2013/003Diffusion; diffusivity between liquids

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  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN201680040098.0A 2015-07-07 2016-07-05 确定样品扩散特性的方法和装置 Active CN107850524B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15175747.3 2015-07-07
EP15175747.3A EP3115768B1 (en) 2015-07-07 2015-07-07 Method and apparatus for determining diffusion properties of a sample
PCT/GB2016/052025 WO2017006107A1 (en) 2015-07-07 2016-07-05 Method and apparatus for determining diffusion properties of a sample

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CN107850524A CN107850524A (zh) 2018-03-27
CN107850524B true CN107850524B (zh) 2021-03-12

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US (1) US11067491B2 (enExample)
EP (1) EP3115768B1 (enExample)
JP (1) JP6835812B2 (enExample)
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WO (1) WO2017006107A1 (enExample)

Families Citing this family (6)

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US20210039096A1 (en) * 2018-04-06 2021-02-11 Redbud Labs, Inc. Magnetic-based actuation mechanisms for and methods of actuating magnetically responsive microposts in a reaction chamber
CN109358023B (zh) * 2018-10-25 2021-01-05 云南大学 一种快速测量随溶液浓度变化的液相扩散系数的平台及方法
CN110794070B (zh) * 2019-11-14 2021-01-05 福特斯(北京)科技有限公司 泰勒扩散分析装置和测定溶液中物质尺寸方法
CN111999231A (zh) * 2020-08-24 2020-11-27 河海大学 混凝土近表面抗氯离子渗透性的试验方法
CN113654952B (zh) * 2021-06-28 2022-07-19 中山大学 一种基于直角三角液槽的扩散系数测量装置与方法
WO2025077984A1 (en) * 2023-10-13 2025-04-17 Fida Biosystems Aps A method of determining a binding parameter between a first particle and a second particle

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0681117A (ja) * 1992-08-10 1994-03-22 Kinzokukei Zairyo Kenkyu Kaihatsu Center 傾斜機能材料の製造法
CA2430578A1 (en) * 2002-05-31 2003-11-30 The University Of Western Ontario Method and apparatus for the detection of noncovalent interactions by mass spectrometry-based diffusion measurements
CN101793902A (zh) * 2010-03-29 2010-08-04 河海大学 一种流动注射快速分析水质余氯的装置及其分析方法
CN101907549A (zh) * 2010-07-06 2010-12-08 南京工业大学 一种同时获取固体溶质在液相中饱和溶解度和扩散系数的测试方法及测试装置
WO2014001409A1 (fr) * 2012-06-26 2014-01-03 Centre National De La Recherche Scientifique (C.N.R.S) Procédé de détermination de la distribution en taille d'un mélange de particules par mise en oeuvre de la dispersion de taylor et système associé

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0681117U (ja) 1993-04-21 1994-11-15 株式会社富士通ゼネラル アンテナ駆動装置の調整機構
US6613580B1 (en) * 1999-07-06 2003-09-02 Caliper Technologies Corp. Microfluidic systems and methods for determining modulator kinetics
AU2003302770B2 (en) 2002-12-20 2007-07-12 Caliper Life Sciences, Inc. Single molecule amplification and detection of DNA
WO2005033672A1 (en) * 2003-10-01 2005-04-14 Caliper Life Sciences, Inc. Method for measuring diffusivities of compounds using microfluidic devices
US20110161062A1 (en) * 2008-09-05 2011-06-30 Comm.A L'ener. Atom. Et Aux Energies Alt Method and device for decontaminating a metallic surface
WO2011042509A2 (en) * 2009-10-08 2011-04-14 Universite De Strasbourg Apparatus and processes for generating variable concentration of solutes in microdroplets
WO2011109245A1 (en) * 2010-03-03 2011-09-09 Wyatt Technology Corporation Method of characterizing interactions and screening for effectors
GB201016992D0 (en) * 2010-10-08 2010-11-24 Paraytec Ltd Viscosity measurement apparatus and method
US20130273564A1 (en) * 2010-12-23 2013-10-17 John Gerard Quinn Dispersion injection methods for biosensing
WO2013002717A1 (en) * 2011-06-30 2013-01-03 Ge Healthcare Bio-Sciences Ab Method of determining active concentration by calibration-free analysis
EP2782628B1 (en) 2011-11-23 2018-10-17 The General Hospital Corporation Prediction, visualization, and control of drug delivery by infusion pumps
GB201219014D0 (en) * 2012-10-23 2012-12-05 Cambridge Entpr Ltd Fluidic device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0681117A (ja) * 1992-08-10 1994-03-22 Kinzokukei Zairyo Kenkyu Kaihatsu Center 傾斜機能材料の製造法
CA2430578A1 (en) * 2002-05-31 2003-11-30 The University Of Western Ontario Method and apparatus for the detection of noncovalent interactions by mass spectrometry-based diffusion measurements
CN101793902A (zh) * 2010-03-29 2010-08-04 河海大学 一种流动注射快速分析水质余氯的装置及其分析方法
CN101907549A (zh) * 2010-07-06 2010-12-08 南京工业大学 一种同时获取固体溶质在液相中饱和溶解度和扩散系数的测试方法及测试装置
WO2014001409A1 (fr) * 2012-06-26 2014-01-03 Centre National De La Recherche Scientifique (C.N.R.S) Procédé de détermination de la distribution en taille d'un mélange de particules par mise en oeuvre de la dispersion de taylor et système associé

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
An analytical method of calculating variable diffusion coefficients;N. SARAFIANOS;《JOURNAL OF MATERIALS SCIENCE》;19860731;第21卷;第2283-2288页 *
Analytic computations of nonideal corrections to blast wave overpressure predictions at high altitudes;Seyi Latunde Dada;《JOURNAL OF GEOPHYSICAL RESEARCH: ATMOSPHERES》;20131004;第118卷;第10830-18038页 *
Application of Taylor Dispersion Technique to Measure Molecular Diffusion Coefficient of Hexane-Bitumen System;Mohsen Ghanavati 等;《AICHE JOURNAL》;20140731;第60卷(第7期);第1-77页 *
Boltzmann Transformation of Taylor Dispersion Profiles to Determine Concentration-Dependent Diffusion Coefficients. Aqueous Cetylpyridinium Chloride near the Critical Micelle Concentration;Derek G. Leaist;《BERICHTE DER BUNSEN-GESELLSCHAFT-PHYSICAL CHEMISTRY CHEMICAL PHYSICS》;19910131;第95卷(第2期);第113-117页 *
Determination of Individual Diffusion Coefficients in Evolving Binary Mixtures by Taylor Dispersion Analysis: Application to the Monitoring of Polymer Reaction;Cottet Herve 等;《ANALYTICAL CHEMISTRY》;20100301;第85卷(第5期);第1793-1802页 *
利用泰勒分析和动态涂层毛细管电泳系统快速测定蛋白质的扩散系数;左敏 等;《高等学校化学学报》;20071031;第28卷;第1875-1877页 *
采用泰勒分散法测量蜡分子扩散系数;陈普敏 等;《化工学报》;20140228;第65卷(第2期);第605-612页 *
陈普敏 等.采用泰勒分散法测量蜡分子扩散系数.《化工学报》.2014,第65卷(第2期), *

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Publication number Publication date
JP6835812B2 (ja) 2021-02-24
WO2017006107A1 (en) 2017-01-12
US20180188147A1 (en) 2018-07-05
EP3115768B1 (en) 2017-12-27
CN107850524A (zh) 2018-03-27
JP2018527556A (ja) 2018-09-20
US11067491B2 (en) 2021-07-20
EP3115768A1 (en) 2017-01-11

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