CN107823012A - A kind of cosmetic composition containing apricot kernel oil - Google Patents

A kind of cosmetic composition containing apricot kernel oil Download PDF

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Publication number
CN107823012A
CN107823012A CN201711341985.4A CN201711341985A CN107823012A CN 107823012 A CN107823012 A CN 107823012A CN 201711341985 A CN201711341985 A CN 201711341985A CN 107823012 A CN107823012 A CN 107823012A
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Prior art keywords
kernel oil
apricot kernel
composition containing
cosmetic composition
aqueous phase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201711341985.4A
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Chinese (zh)
Inventor
沈华忠
李易珊
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jane (guangzhou) Cosmetics Co Ltd
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Jane (guangzhou) Cosmetics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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Priority to CN201711341985.4A priority Critical patent/CN107823012A/en
Publication of CN107823012A publication Critical patent/CN107823012A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A61K8/988Honey; Royal jelly, Propolis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)

Abstract

Invention provides a kind of cosmetic composition containing apricot kernel oil, is made up of following raw material:Apricot kernel oil, breast wooden fruit, fish pelargonium, astragalus root, Radix Angelicae Sinensis, hyaluronic acid, glycerine, Rosa Damascana, propolis, papain and honeysuckle, compared with prior art, the present invention has following beneficial effect:Can apply to user face, have it is good the effect of cleaning, be antipruritic, anti-inflammatory is antibacterial, also with good penetrability, the advantages of easily absorption, can effective skin care, play a part of good whitening, moisturizing, exfoliating and tender skin, be worthy to be popularized.

Description

A kind of cosmetic composition containing apricot kernel oil
Technical field
The present invention is a kind of cosmetic composition containing apricot kernel oil, belongs to cosmetic field.
Background technology
Face cream, cosmetic mud are the most important steps of basic skin care, and whitening and anti-aging in face cream, cosmetic mud etc. is effectively Composition can preferably by percutaneous absorption, so, possess one bottle of good face cream be it is very important, in the market occur face Frost, majority is all containing a large amount of chemical substances, it is well known that many chemical substances are to have certain toxicity to the mankind, if Choose it is improper will result in immeasurable loss, at present, on the market many face creams make when, chemical substance from exist The problem of very big.
The content of the invention
In view of the deficienciess of the prior art, it is an object of the present invention to provide a kind of cosmetic composition containing apricot kernel oil, To solve the problems mentioned in the above background technology.
To achieve these goals, the present invention is to realize by the following technical solutions:A kind of change containing apricot kernel oil Cosmetic compositions, it is made up of following raw material:Apricot kernel oil, the wooden fruit of breast, fish pelargonium, astragalus root, Radix Angelicae Sinensis, hyaluronic acid, glycerine, rose Essential oil, propolis, papain and honeysuckle.
Further, honey is put in pot, be heated to after seething with excitement slowly, used slow fire instead and keep micro-boiling, drag for and float on the surface Foam and wax, then use or gauze filter off impurity, after being diluted with boiling water, drench people 2.5~3.5cm of diameter, thickness 0.2~ 0.4cm, exocuticle is shallow pale brown or astragalus mongholicus tablet of sepia in, mix thoroughly, vexed profit 4-6 hours, then put astragalus mongholicus tablet in frying pan, With slow fire frying, fry it is deep yellow uniformly to astragalus root color, it is glossy, then take out, cool, extracted using the method for supercritical extract Pick and place it is cool after astragalus mongholicus tablet, that is, obtain raw material in astragalus root.
Further, the dry root of umbelliferae angelica is taken, fibrous root and silt is removed, after moisture evaporation, is bundled into small , upper canopy, with pyrotechnics slowly smoke-dried beancurd, after drying, it is put into pulverizer and crushes, cross 50 mesh sieves, sieves to obtain Radix Angelicae Sinensis in raw material.
Further, cockscomb fragment is added in acetone, soaked overnight to cockscomb dehydration is hardened, and is subsequently placed in porcelain dish It is dried, crushes powdering through pulverizer after drying, cockscomb powder is poured into enamel pot, adds 6~7 times of distilled water, stirring Uniformly, more than 24h is soaked, cockscomb powder is fully swelled, then filters, collects filtrate, filter residue soaks 3 times in the same way again, Merge 3 filtered fluids, then filtrate is poured into ceramic cylinder, stir the solid sodium chloride of lower addition 10%, and add isometric chlorine It is imitative, after stirring 3h, aqueous phase is separated, 95% ethanol of 2 times of volumes is added into the aqueous phase separated, is stirred, stands more than 12h, Hyaluronic acid is settled out, is then filtered dry sediment, obtains crude product after drying, crude product is re-dissolved in the 0.1mol/L sodium chloride of 4 times of volumes In solution, pH=4.5~5 are adjusted with watery hydrochloric acid, add isometric chloroform, after stratification, suction out upper strata aqueous phase, aqueous phase PH=7.5 are adjusted with 8% sodium hydroxide solution, add pronase, 24h are incubated at 37 DEG C, then extracted with isometric chloroform Handle 2 times, merging upper strata aqueous phase, lower floor's liquids recovery chloroform, it is molten to add 1% isometric cetylpyridinium chloride in aqueous phase Liquid, stir, staticly settle, filter, collect precipitation, precipitation is dissolved with the 0.4mol/L sodium chloride of 2~3 times of volumes again, mistake Filter, add 3 times of ethanol of volume 95% in filtrate, staticly settle, suck upper strata ethanol, lower floor is again with 95% ethanol repeated precipitation 2 Secondary, lower sediment thing hangs filter, dries, then is washed 2 times with acetone, is dried in vacuo, obtains the hyaluronic acid in raw material.
Further, plucked in batches when honeysuckle blooms, in two batches, first is in 5 months, the last ten-days period, in 6 months, the last ten-days period Adopt second of flower, when bud top expands, by it is green bleach, it is not yet open when harvest, dry or dry immediately after harvesting, drying temperature Spend and be, just dry 30~35 DEG C, 40 DEG C are risen to after 2h, dry 5~10h, after then controlling room temperature to be kept for 45~50 DEG C dry 10h, heating To 55~60 DEG C, honeysuckle is dried rapidly, then dried honeysuckle be placed in pulverizer and crushed, cross 50 mesh sieves, Sieve to obtain honeysuckle in raw material.
Beneficial effects of the present invention:A kind of cosmetic composition containing apricot kernel oil of the present invention, rich in mineral matter, albumen Matter and various vitamins, it is the splendid vegetable oil of a kind of skin care and moisturizing effect, suitable for various skin quality.It can be effectively Mitigate skin people and itch phenomenon, eliminate red and swollen, dry and inflammation.The sagging gland of brain, thymus gland and the adrenal gland of internal system can be stimulated, Promote cell turnover, apricot kernel oil can make skin recover smooth soft and fine, be met if long-term use can effectively eliminate gestation.By It is extremely gentle in Sweet Almond Oil, therefore connect baby and can use, the myalgia caused further for hyperkinesia, if with sweet tea Apricot kernel oil massage can strengthen cell band oxygen function, and dispelling fatigue is accumulated with carbonic acid, has analgesia and abirritant effect, this hair Cosmetics made of bright, can apply to user face, with good the effect of cleaning, be antipruritic, anti-inflammatory is antibacterial, also have and ooze Permeability is good, the advantages of easily absorption, can effective skin care, play the work of good whitening, moisturizing, exfoliating and tender skin With being worthy to be popularized.
Embodiment
To be easy to understand the technical means, the inventive features, the objects and the advantages of the present invention, with reference to Embodiment, the present invention is expanded on further.
The present invention provides a kind of technical scheme:A kind of cosmetic composition containing apricot kernel oil, is made up of following raw material:Apricot Benevolence oil, breast wooden fruit, fish pelargonium, astragalus root, Radix Angelicae Sinensis, hyaluronic acid, glycerine, Rosa Damascana, propolis, papain and gold Honeysuckle flower.
Honey is put in pot, is heated to after seething with excitement slowly, slow fire is used instead and keeps micro-boiling, drag for supernatant foam and wax Matter, is then used or gauze filters off impurity, after being diluted with boiling water, drenches people 2.5~3.5cm of diameter, 0.2~0.4cm of thickness, exocuticle is shallow In pale brown or sepia astragalus mongholicus tablet, mix thoroughly, vexed profit 4-6 hours, then put astragalus mongholicus tablet in frying pan, with slow fire frying, fry extremely Astragalus root color is deep yellow uniformly, glossy, then takes out, cools, the Radix Astragali after being cooled using the method extraction of supercritical extract Piece, that is, obtain the astragalus root in raw material.
The dry root of umbelliferae angelica is taken, removes fibrous root and silt, after moisture evaporation, wisp is bundled into, upper canopy, uses Pyrotechnics slowly smoke-dried beancurd, after drying, it is put into pulverizer and crushes, cross 50 mesh sieves, sieves to obtain Radix Angelicae Sinensis in raw material.
Cockscomb fragment is added in acetone, soaked overnight to cockscomb dehydration is hardened, and is subsequently placed in porcelain dish and is dried, Powdering is crushed through pulverizer after drying, cockscomb powder is poured into enamel pot, 6~7 times of distilled water is added, stirs, is soaked More than 24h, cockscomb powder is fully swelled, then filter, collect filtrate, filter residue soaks 3 times in the same way again, merges 3 mistakes Filtrate, then filtrate is poured into ceramic cylinder, the solid sodium chloride of lower addition 10% is stirred, and isometric chloroform is added, stir 3h Afterwards, aqueous phase is separated, 95% ethanol of 2 times of volumes is added into the aqueous phase separated, is stirred, more than 12h is stood, is settled out Bright matter acid, is then filtered dry sediment, and crude product is obtained after drying, and crude product is re-dissolved in the 0.1mol/L sodium chloride solutions of 4 times of volumes, is used Watery hydrochloric acid adjusts pH=4.5~5, adds isometric chloroform, after stratification, suctions out upper strata aqueous phase, 8% hydroxide of aqueous phase Sodium solution adjusts pH=7.5, adds pronase, is incubated 24h at 37 DEG C, then with isometric chloroform extraction processing 2 times, closes And upper strata aqueous phase, lower floor's liquids recovery chloroform, 1% isometric cetylpyridinium chloride solution is added in aqueous phase, stirring is equal It is even, staticly settle, filter, collect precipitation, precipitation is dissolved with the 0.4mol/L sodium chloride of 2~3 times of volumes again, filtering, in filtrate 3 times of ethanol of volume 95% are added, are staticly settled, suck upper strata ethanol, again with 95% ethanol repeated precipitation 2 times, lower floor sinks for lower floor Starch hangs filter, dries, then is washed 2 times with acetone, is dried in vacuo, obtains the hyaluronic acid in raw material.
Plucked in batches when honeysuckle blooms, in two batches, first is in 5 months, the last ten-days period, in 6 months, the last ten-days period adopt second Flower, when bud top expands, by it is green bleach, it is not yet open when harvest, dry or dry immediately after harvesting, drying temperature is, just 30~35 DEG C are dried, 40 DEG C are risen to after 2h, dries 5~10h, after then controlling room temperature to be kept for 45~50 DEG C dry 10h, is warming up to 55~60 DEG C, honeysuckle is dried rapidly, then dried honeysuckle is placed in pulverizer and crushed, cross 50 mesh sieves, sieve to obtain raw material In honeysuckle.
As one embodiment of the present of invention:A kind of cosmetic composition containing apricot kernel oil of the present invention, rich in mineral Matter, protein and various vitamins, it is the splendid vegetable oil of a kind of skin care and moisturizing effect, suitable for various skin quality.It Skin people and itch phenomenon can effectively be mitigated, eliminate red and swollen, dry and inflammation.The sagging gland of brain, the thymus gland of internal system can be stimulated And adrenal gland, promote cell turnover, apricot kernel oil can make skin recover it is smooth soft and fine, if long-term use can effectively eliminate it is pregnant It is pregnent and meets.Because Sweet Almond Oil is extremely gentle, therefore connects baby and can use, the myalgia caused further for hyperkinesia Bitterly, if can strengthen cell band oxygen function with Sweet Almond Oil massage, dispelling fatigue and carbonic acid are accumulated, and have analgesia and abirritant Effect, cosmetics made of the present invention, can apply to user face, have it is good clean, be antipruritic, the work(that anti-inflammatory is antibacterial Effect, also with good penetrability, the advantages of easily absorption, can effective skin care, play good whitening, moisturizing, exfoliating And the effect of tender skin, it is worthy to be popularized.
The general principle and principal character and advantages of the present invention of the present invention has been shown and described above, for this area skill For art personnel, it is clear that the invention is not restricted to the details of above-mentioned one exemplary embodiment, and without departing substantially from the present invention spirit or In the case of essential characteristic, the present invention can be realized in other specific forms.Which point therefore, no matter from the point of view of, all should incite somebody to action Embodiment regards exemplary as, and be it is nonrestrictive, the scope of the present invention by appended claims rather than on state Bright restriction, it is intended that all changes fallen in the implication and scope of the equivalency of claim are included in the present invention It is interior.
Moreover, it will be appreciated that although the present specification is described in terms of embodiments, not each embodiment is only wrapped Containing an independent technical scheme, this narrating mode of specification is only that those skilled in the art should for clarity Using specification as an entirety, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art It is appreciated that other embodiment.

Claims (5)

  1. A kind of 1. cosmetic composition containing apricot kernel oil, it is characterised in that:It is made up of following raw material:Apricot kernel oil, the wooden fruit of breast, day Zhu Kui, astragalus root, Radix Angelicae Sinensis, hyaluronic acid, glycerine, Rosa Damascana, propolis, papain and honeysuckle.
  2. A kind of 2. cosmetic composition containing apricot kernel oil according to claim 1, it is characterised in that:Honey is put into pot It is interior, it is heated to after seething with excitement slowly, uses slow fire instead and keep micro-boiling, drag for supernatant foam and wax, then uses or gauze is filtered Decontamination, after being diluted with boiling water, drench people 2.5~3.5cm of diameter, 0.2~0.4cm of thickness, exocuticle is shallow pale brown or Huang of sepia In stilbene piece, mix thoroughly, vexed profit 4-6 hours, then put astragalus mongholicus tablet in frying pan, with slow fire frying, fry deep yellow to astragalus root color It is even, it is glossy, then take out, cool, the astragalus mongholicus tablet after being cooled using the method extraction of supercritical extract, that is, obtain in raw material Astragalus root.
  3. A kind of 3. cosmetic composition containing apricot kernel oil according to claim 1, it is characterised in that:Take samphire The dry root of Radix Angelicae Sinensis, fibrous root and silt are removed, after moisture evaporation, be bundled into wisp, upper canopy, with pyrotechnics slowly smoke-dried beancurd, after drying, It is put into pulverizer and crushes, cross 50 mesh sieves, sieves to obtain Radix Angelicae Sinensis in raw material.
  4. A kind of 4. cosmetic composition containing apricot kernel oil according to claim 1, it is characterised in that:Cockscomb fragment is added Enter into acetone, soaked overnight to cockscomb dehydration is hardened, and is subsequently placed in porcelain dish and is dried, is ground into after drying through pulverizer Powdery, cockscomb powder is poured into enamel pot, add 6~7 times of distilled water, stir, soaked more than 24h, make cockscomb powder abundant Swelling, is then filtered, and collects filtrate, and filter residue soaks 3 times in the same way again, merges 3 filtered fluids, then filtrate is poured into ceramics In cylinder, the solid sodium chloride of lower addition 10% is stirred, and adds isometric chloroform, after stirring 3h, aqueous phase is separated, to what is separated 95% ethanol of 2 times of volumes is added in aqueous phase, is stirred, more than 12h is stood, is settled out hyaluronic acid, is then filtered dry precipitation Thing, after drying crude product, crude product is re-dissolved in the 0.1mol/L sodium chloride solutions of 4 times of volumes, with watery hydrochloric acid adjust pH=4.5~ 5, add isometric chloroform, after stratification, suction out upper strata aqueous phase, aqueous phase 8% sodium hydroxide solution regulation pH=7.5, Pronase is added, is incubated 24h at 37 DEG C, then with isometric chloroform extraction processing 2 times, merges upper strata aqueous phase, subnatant Body reclaims chloroform, adds 1% isometric cetylpyridinium chloride solution in aqueous phase, stirs, staticly settle, and filters, and receives Collection precipitation, precipitation are dissolved with the 0.4mol/L sodium chloride of 2~3 times of volumes again, filtering, and 3 times of second of volume 95% are added in filtrate Alcohol, staticly settle, suck upper strata ethanol, again with 95% ethanol repeated precipitation 2 times, lower sediment thing hangs filter, dries, then use for lower floor Acetone washs 2 times, vacuum drying, obtains the hyaluronic acid in raw material.
  5. A kind of 5. cosmetic composition containing apricot kernel oil according to claim 1, it is characterised in that:Bloomed in honeysuckle When pluck in batches, in two batches, first is in 5 months, the last ten-days period, in 6 months, the last ten-days period adopt second of flower, when bud top is expanded, by green Harvested when bleaching, be not yet open, dry or dry immediately after harvesting, drying temperature is just to dry 30~35 DEG C, 40 are risen to after 2h DEG C, 5~10h is dried, after then controlling room temperature to be kept for 45~50 DEG C dry 10h, 55~60 DEG C is warming up to, honeysuckle is dried rapidly, Then dried honeysuckle is placed in pulverizer and crushed, cross 50 mesh sieves, sieve to obtain honeysuckle in raw material.
CN201711341985.4A 2017-12-14 2017-12-14 A kind of cosmetic composition containing apricot kernel oil Pending CN107823012A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108379217A (en) * 2018-04-26 2018-08-10 曾颂 A kind of more effect skin-active liquefaction cosmetic
CN115317413A (en) * 2022-04-13 2022-11-11 太原理工大学 Formula with virus 3CL protease inhibitory activity and preparation method of paste composition

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102429853A (en) * 2011-12-24 2012-05-02 大连创达技术交易市场有限公司 Special purely natural isolation cream for pregnant women
CN106377494A (en) * 2016-12-12 2017-02-08 珍尔姿(广州)化妆品有限公司 Whitening and wrinkle removal functional mask

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102429853A (en) * 2011-12-24 2012-05-02 大连创达技术交易市场有限公司 Special purely natural isolation cream for pregnant women
CN106377494A (en) * 2016-12-12 2017-02-08 珍尔姿(广州)化妆品有限公司 Whitening and wrinkle removal functional mask

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
郑惠文: "《美容养颜该怎么吃》", 30 June 2014, 中国纺织出版社 *
高学敏,等: "《中医美容学》", 31 January 2000, 中国科学技术出版社 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108379217A (en) * 2018-04-26 2018-08-10 曾颂 A kind of more effect skin-active liquefaction cosmetic
CN115317413A (en) * 2022-04-13 2022-11-11 太原理工大学 Formula with virus 3CL protease inhibitory activity and preparation method of paste composition

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