CN107820423A - 用于预防和/或治疗上呼吸道感染的聚肌苷酸‑聚胞苷酸(聚(i:c))豌豆淀粉制剂 - Google Patents

用于预防和/或治疗上呼吸道感染的聚肌苷酸‑聚胞苷酸(聚(i:c))豌豆淀粉制剂 Download PDF

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Publication number
CN107820423A
CN107820423A CN201680040346.1A CN201680040346A CN107820423A CN 107820423 A CN107820423 A CN 107820423A CN 201680040346 A CN201680040346 A CN 201680040346A CN 107820423 A CN107820423 A CN 107820423A
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CN
China
Prior art keywords
composition
microparticles
starch
polyinosinic
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201680040346.1A
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English (en)
Chinese (zh)
Inventor
A.H.范迪克
J.门施
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Sciences Ireland ULC
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Janssen Sciences Ireland ULC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Sciences Ireland ULC filed Critical Janssen Sciences Ireland ULC
Publication of CN107820423A publication Critical patent/CN107820423A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L3/00—Compositions of starch, amylose or amylopectin or of their derivatives or degradation products
    • C08L3/02—Starch; Degradation products thereof, e.g. dextrin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN201680040346.1A 2015-05-11 2016-05-10 用于预防和/或治疗上呼吸道感染的聚肌苷酸‑聚胞苷酸(聚(i:c))豌豆淀粉制剂 Pending CN107820423A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15167129 2015-05-11
EP15167129.4 2015-05-11
PCT/IB2016/000890 WO2016181226A1 (en) 2015-05-11 2016-05-10 Polyinosinic-polycytidylic acid (poly(i:c)) pea starch formulation for the prevention and/or treatment of upper respiratory tract infections

Publications (1)

Publication Number Publication Date
CN107820423A true CN107820423A (zh) 2018-03-20

Family

ID=53174864

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201680040346.1A Pending CN107820423A (zh) 2015-05-11 2016-05-10 用于预防和/或治疗上呼吸道感染的聚肌苷酸‑聚胞苷酸(聚(i:c))豌豆淀粉制剂

Country Status (12)

Country Link
US (1) US20180353533A1 (enExample)
EP (1) EP3294268A1 (enExample)
JP (1) JP2018515530A (enExample)
KR (1) KR20180004233A (enExample)
CN (1) CN107820423A (enExample)
AU (1) AU2016259869A1 (enExample)
CA (1) CA2983659A1 (enExample)
HK (1) HK1251926A1 (enExample)
MA (1) MA44384A (enExample)
RU (1) RU2017142710A (enExample)
TW (1) TW201705963A (enExample)
WO (1) WO2016181226A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114917242A (zh) * 2022-05-31 2022-08-19 复旦大学附属中山医院 合成双链rna类似物经滴鼻预防呼吸道传播病毒的应用及其用途

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7376480B2 (ja) * 2018-07-20 2023-11-08 株式会社 資生堂 ウイルス不活化剤
CU20200110A7 (es) * 2020-12-23 2022-08-09 Ct Ingenieria Genetica Biotecnologia Péptidos para el tratamiento de infecciones respiratorias de origen viral
KR102439760B1 (ko) 2021-03-09 2022-09-02 주식회사 오라팜 상기도 감염균 질환 예방 및 치료를 위한 조성물
KR102451861B1 (ko) 2021-03-09 2022-10-07 주식회사 오라팜 급성 호흡기 바이러스 및 로타바이러스 감염 질환 예방 및 치료를 위한 조성물

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101757018A (zh) * 2008-12-24 2010-06-30 天津瑞普生物技术股份有限公司 一种用于畜禽的聚肌胞干粉及其制备方法
CN102988303A (zh) * 2011-09-15 2013-03-27 天津泽世德生物医药有限公司 一种多聚肌苷酸多聚胞苷酸冻干粉针的制备方法
CN104394846A (zh) * 2012-05-03 2015-03-04 爱尔兰詹森研发公司 用于治疗上呼吸道感染的聚肌苷酸-聚胞苷酸(聚(i:c))配制品
WO2015067632A1 (en) * 2013-11-06 2015-05-14 Janssen Sciences Ireland Uc Polylnosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections

Family Cites Families (4)

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Publication number Priority date Publication date Assignee Title
US5707644A (en) * 1989-11-04 1998-01-13 Danbiosyst Uk Limited Small particle compositions for intranasal drug delivery
CN101229378A (zh) * 2005-05-05 2008-07-30 国家淀粉及化学投资控股公司 用于送递活性剂的组合物
JP2009209086A (ja) * 2008-03-04 2009-09-17 Masami Moriyama 粘膜投与型ワクチン
TWI643082B (zh) * 2013-09-03 2018-12-01 美商新思科技股份有限公司 一種佈線出一解決路徑之方法及系統

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101757018A (zh) * 2008-12-24 2010-06-30 天津瑞普生物技术股份有限公司 一种用于畜禽的聚肌胞干粉及其制备方法
CN102988303A (zh) * 2011-09-15 2013-03-27 天津泽世德生物医药有限公司 一种多聚肌苷酸多聚胞苷酸冻干粉针的制备方法
CN104394846A (zh) * 2012-05-03 2015-03-04 爱尔兰詹森研发公司 用于治疗上呼吸道感染的聚肌苷酸-聚胞苷酸(聚(i:c))配制品
WO2015067632A1 (en) * 2013-11-06 2015-05-14 Janssen Sciences Ireland Uc Polylnosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
马力: "《食品化学与营养学》", 30 September 2007, 中国轻工业出版社 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114917242A (zh) * 2022-05-31 2022-08-19 复旦大学附属中山医院 合成双链rna类似物经滴鼻预防呼吸道传播病毒的应用及其用途

Also Published As

Publication number Publication date
WO2016181226A1 (en) 2016-11-17
KR20180004233A (ko) 2018-01-10
EP3294268A1 (en) 2018-03-21
HK1251926A1 (zh) 2019-05-03
RU2017142710A (ru) 2019-06-11
MA44384A (fr) 2019-01-23
TW201705963A (zh) 2017-02-16
JP2018515530A (ja) 2018-06-14
US20180353533A1 (en) 2018-12-13
AU2016259869A1 (en) 2017-11-30
CA2983659A1 (en) 2016-11-17

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