CN107817195A - Particle size distribution measuring method of the electronic cigarette solution additive in flue gas aerosol - Google Patents
Particle size distribution measuring method of the electronic cigarette solution additive in flue gas aerosol Download PDFInfo
- Publication number
- CN107817195A CN107817195A CN201710988300.9A CN201710988300A CN107817195A CN 107817195 A CN107817195 A CN 107817195A CN 201710988300 A CN201710988300 A CN 201710988300A CN 107817195 A CN107817195 A CN 107817195A
- Authority
- CN
- China
- Prior art keywords
- flue gas
- electronic cigarette
- additive
- size distribution
- aerosol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/02—Investigating particle size or size distribution
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
- G01N30/14—Preparation by elimination of some components
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/72—Mass spectrometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
- G01N2030/062—Preparation extracting sample from raw material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
- G01N30/14—Preparation by elimination of some components
- G01N2030/146—Preparation by elimination of some components using membranes
Abstract
The present invention relates to a kind of particle size distribution measuring method of electronic cigarette solution additive in flue gas aerosol, belong to electronic cigarette research field, specifically additive is added in electronic cigarette tobacco leaf, aspirated according to required suction mode, by electronics low pressure impactor（ELPI）The flue gas aerosol of electronic cigarette different-grain diameter is trapped, gas chromatography-mass spectrometry is used after processing（GC‑MS）The measure of thing is added, obtains distribution situation of the additive in different-grain diameter flue gas, is that tobacco juice for electronic smoke formulating and the improvement of electronic cigarette flue gas organoleptic quality etc. provide technical support.
Description
Technical field
The invention belongs to electronic cigarette technical field, grain of specifically a kind of electronic cigarette solution additive in flue gas aerosol
Footpath distribution determination method.
Background technology
Electronic cigarette by heat tobacco tar atomization produce flue gas, make wherein using glycerine, propane diols etc. as Alevaire mainly into
Point, nicotine and fragrance component etc. be atomized as the tobacco juice of active ingredient, generation supplies the flue gas aerosol that human body is sucked.At present
Correlative study person's research shows that flue gas aerosol particle diameter caused by different electronic cigarette liquid formulas is different, the change of different-grain diameter aerosol
It is also different to learn composition.Different-grain diameter aerosol particle is deposited on different parts after entering respiratory system, such as aerosol in large grain size
Grain is most of to remain in oral cavity and nasal cavity, and small particle aerosol remains in lung, because oral cavity and nasal cavity are to different-grain diameter, difference
Chemical composition forms the sensorial differences of flue gas, and then can influence the organoleptic quality of flue gas.Therefore different electronic cigarette liquid additions are analyzed
Distributional difference of the agent in different-grain diameter aerosol improves to tobacco juice for electronic smoke formulating and electronic cigarette flue gas organoleptic quality
Etc. significant.
In addition, electronic cigarette and traditional cigarette, heating are not burnt cigarette produce flue gas mode it is different, traditional cigarette passes through cigarette
The burning of grass produces smog, heats the cigarette that do not burn and produces smog by heating system heats tobacco, electronic cigarette then passes through electricity
Heating system Atmized electronic cigarrette tobacco juice, to reach the purpose for producing smog.Due to flue gas source, producing method, flue gas generation temperature
There is larger difference in degree etc., therefore caused flue gas physicochemical property has significant difference, therefore studies electronic cigarette liquid additive and exist
The analysis method being distributed in aerosol and traditional cigarette and the heating cigarette that do not burn are different.
Distribution of the report electronic cigarette solution additive in different-grain diameter aerosol is had no at present, researchs and develops electronic cigarette
The assay method that solution additive is distributed in different-grain diameter flue gas, it is tobacco juice for electronic smoke formulating and electronic cigarette flue gas sense
Official's quality improving etc. provides technical support.
The content of the invention
The purpose of the present invention is based on above-mentioned prior art situation and the demand of tobacco juice for electronic smoke Formula Development, there is provided one
Particle size distribution measuring method of the kind electronic cigarette solution additive in flue gas aerosol, tobacco juice for electronic smoke is obtained by this method and added
Add distribution situation of the agent in electronic cigarette different-grain diameter flue gas aerosol.
The object of the present invention is achieved like this, and additive is added in tobacco juice for electronic smoke, entered according to required suction mode
Row suction, by electronics low pressure impactor（ELPI）The flue gas aerosol of different-grain diameter is trapped, gas-chromatography-matter is used after processing
Compose combined instrument（GC-MS）The measure of thing is added, realizes distribution of the additive in different-grain diameter electronics smoke sol, for electricity
Sub- cigarette tobacco juice formulating and electronic cigarette flue gas organoleptic quality, which improves, provides technical support.
The method of the present invention comprises the following steps：
Step（1）Additive is made an addition in tobacco juice for electronic smoke by the 0.005 ~ 95% of tobacco juice weight.
Step（2）Electronic cigarette suction is carried out with one channel smoke sucking machine, suction mode is the mL of pumping volume 15 ~ 250, suction
Duration is 0.5 ~ 12s, and Puffing interval is 4 ~ 200 s, and puffing profile is bell or square.
Step（3）Flue gas imports ELPI after diluting 100 ~ 10000 times, and cigarette is trapped with the 12 grades of filter membranes equipped in advance on ELPI
Gas aerosol, trap the aerosol of 5 ~ 400 mouthfuls of flue gases；
Step（4）Filter membrane after trapping is placed in 10 mL vials, 1 ~ 50 mL methanol or water is added or dichloromethane is molten
Liquid, 2 ~ 30min of ultrasonic extraction, extraction solution filter through 0.22 μm of aqueous phase or organic phase mocromembrane, add internal standard compound, then use gas phase
Chromatograph-mas spectrometer GC-MS is measured；
Described gas chromatographic detection condition is as follows：
Chromatographic column：Elastic capillary-column, specification are the mm id of 30 m of length × internal diameter 0.25 × um df of thickness 0.25）；Sample introduction
Mouth temperature：250~300℃；Carrier gas：Helium（The % of purity >=99.999）, constant current flow velocity：1.0 mL/min；Sample size：1 μL；No
Split sampling or split sampling（Split ratio 5:1~50:1）；Heating schedule：40 DEG C of initial temperature, 3 min are kept, then with 3
DEG C/min speed is warming up to 240 DEG C, and keeps 15 min.
Described Mass Spectrometer Method condition is as follows：Ionization mode：Electron bombardment ionization source（EI）；Transmission line temperature：240 ℃；Ion
Source temperature：230 ℃；Ionizing energy：70 eV；Solvent delay：3 min；Scanning range：30~350；Scan pattern：Total ion current
Scanning.
Step（5）According to the amount and particle diameter of additive on different-grain diameter, the grain size distribution of additive is drawn.
The step（4）Middle internal standard compound can according to the property of additive select property similar in material.
The step（4）The stationary phase of middle elastic capillary-column can be polyethylene glycol, the poly- silicon of (5%- phenyl) -95% dimethyl
Oxygen alkane or (50%- phenyl)-methyl polysiloxane.
The step（5）Middle grain size distribution can draw 0.1 ~ 10 μm of particle diameter distribution.
The advantages of present invention possesses and effect：This method is easy to operate, as a result accurately, applied widely, the measurement result
Particle diameter distribution of the tobacco juice additive under different suction modes available for evaluation all kinds electronic cigarette, this method can be commented effectively
Influence of the valency different additive to electronic cigarette flue gas aesthetic quality, and be tobacco juice for electronic smoke formulating and electronic cigarette flue gas
Organoleptic quality, which improves, provides foundation.
Brief description of the drawings
Fig. 1 is grain size distribution of the propane diols additive in different-grain diameter flue gas.
Fig. 2 is grain size distribution of the glycerine additive in different-grain diameter flue gas.
Fig. 3 is grain size distribution of the Megastigmatrienone additive in different-grain diameter flue gas.
Fig. 4 is grain size distribution of the menthol additive in different-grain diameter flue gas.
Fig. 5 is grain size distribution of the acetic acid additive in different-grain diameter flue gas.
Embodiment
It will be understood to those of skill in the art that the following example is merely to illustrate the present invention, and it should not be regarded as limiting this hair
Bright scope.In the examples where no specific technique or condition is specified, according to the technology or condition described by document in the art
Or carried out according to product description.Agents useful for same or the unreceipted production firm person of instrument, it is that can be obtained by buying
Conventional products.Below by embodiment, the present invention will be further described,
Embodiment 1
Propane diols has hygroscopicity, slightly sweet taste, is one of the basic ingredient of electronics tobacco tar, mainly as the carrier of essence, goes back
The mouthfeel of tobacco tar can be strengthened, electronic cigarette smoke condition and suction mouthfeel are had a major impact.Addition 90% the third two in tobacco juice for electronic smoke
Alcohol, cigarette smoking, pumping volume 55mL, puff duration 2s, Puffing interval 60 are carried out with one channel smoke sucking machine
S, puffing profile are bell；By flue gas through dilution（9000 times of extension rate）After import ELPI, with 12 grades equipped in advance on ELPI
Filter membrane traps cigarette flue gas aerosol, traps 10 mouthfuls of flue gas aerosols；Then every grade of filter membrane is respectively placed in 12 10mL glass
In bottle, the 20.0 mL aqueous solution are sequentially added, ultrasonic extraction 10min, are removed, extraction solution filters through 0.22 μm of aqueous phase mocromembrane, adds
Enter 1,2-PD-D6 internal standard substance solutions, then GC-MS is measured, and obtains the concentration of propane diols, so as to according to particle size range
<0.03 μm, 0.04 μm, 0.07 μm, 0.14 μm and 0.26 μm drafting propane diols distribution map, as shown in Figure 1.
Described gas chromatographic detection condition is as follows：
Chromatographic column：Elastic capillary-column, stationary phase are polyethylene glycol, and specification is the mm id of 30 m of length × internal diameter 0.25 × thickness
0.25 um df；Injector temperature：280 ℃；Carrier gas：Helium（The % of purity >=99.999）, constant current flow velocity：1.0 mL/min；Enter
Sample amount：1 μL；Split sampling, split ratio 50:1；Heating schedule：40 DEG C of initial temperature, 3 min are kept, then with 3 DEG C/min
Speed be warming up to 240 DEG C, and keep 15 min.
Described Mass Spectrometer Method condition is as follows：Ionization mode：Electron bombardment ionization source（EI）；Transmission line temperature：240 ℃；Ion
Source temperature：230 ℃；Ionizing energy：70 eV；Solvent delay：5 min；Scanning range：30~350；Scan pattern：Total ion current
Scanning.
Embodiment 2
Glycerine has high-hygroscopicity, has certain sweet taste, is to produce fog in tobacco juice for electronic smoke main function.Tobacco juice for electronic smoke
20% glycerine of middle addition, cigarette smoking is carried out with one channel smoke sucking machine, pumping volume 100mL, puff duration 0.6s,
Puffing interval is 100 s, and puffing profile is square；By flue gas through dilution（5000 times of extension rate）After import ELPI, use
The 12 grades of filter membranes trapping cigarette flue gas aerosol equipped in advance on ELPI, traps 20 mouthfuls of flue gas aerosols；Then by every grade of filter membrane point
It is not placed in 12 10mL vials, sequentially adds 45.0 mL methanol solutions, ultrasonic extraction 20min, remove, extraction solution warp
0.22 μm of organic phase mocromembrane filtering, adds deuterated glycerine-D5 internal standard substance solutions, and then GC-MS is measured, and obtains glycerine
Concentration, so as to according to particle size range<0.03 μm, 0.04 μm, 0.07 μm and ＞ 0.1 μm of drafting glycerine distribution map, such as schemes
Shown in 2.
Described gas chromatographic detection condition is as follows：
Chromatographic column：Elastic capillary-column, stationary phase are polyethylene glycol, and specification is the mm id of 30 m of length × internal diameter 0.25 × thickness
0.25 um df；Injector temperature：300 ℃；Carrier gas：Helium（The % of purity >=99.999）, constant current flow velocity：1.0 mL/min；Enter
Sample amount：1 μL；Split sampling, split ratio 30:1；Heating schedule：40 DEG C of initial temperature, 3 min are kept, then with 3 DEG C/min
Speed be warming up to 240 DEG C, and keep 15 min.
Described Mass Spectrometer Method condition is as follows：Ionization mode：Electron bombardment ionization source（EI）；Transmission line temperature：240 ℃；Ion
Source temperature：230 ℃；Ionizing energy：70 eV；Solvent delay：5 min；Scanning range：30~350；Scan pattern：Total ion current
Scanning.
Embodiment 3
Megastigmatrienone is a kind of important perfume ingredient in tobacco juice for electronic smoke, has fragrant and sweet herbal medicine taste, pungent fragrant bottom rhythm, to electronics
Cigarette perfume is jealous to be had a major impact.0.008% Megastigmatrienone is added in tobacco juice for electronic smoke, carrying out cigarette with one channel smoke sucking machine takes out
Inhale, the mL of pumping volume 250, puff duration is 10 s, and Puffing interval is 10 s, and puffing profile is bell；By flue gas
Through dilution（2500 times of extension rate）After import ELPI, trap cigarette flue gas aerosol with 12 grades of filter membranes being equipped in advance on ELPI,
Trap 300 mouthfuls of flue gas aerosols；Then every grade of filter membrane is respectively placed in 12 10mL vials, sequentially adds 2.0 mL dichloros
Dichloromethane, ultrasonic extraction 4min, is removed, extraction solution filtered through 0.22 μm of organic phase mocromembrane, add deuterated hydrocinnamic acid-
D5 internal standard substance solutions, then GC-MS be measured, the concentration of Megastigmatrienone is obtained, so as to according to particle size range<0.03 μm、
0.04~0.07 μm and ＞ 0.07 μm of drafting Megastigmatrienone distribution map, as shown in Figure 3.
Described gas chromatographic detection condition is as follows：
Chromatographic column：Elastic capillary-column, stationary phase are (50%- phenyl)-methyl polysiloxane, and specification is 30 m of length × internal diameter
The 0.25 mm id × um df of thickness 0.25；Injector temperature：250 ℃；Carrier gas：Helium（The % of purity >=99.999）, constant current stream
Speed：1.0 mL/min；Sample size：1 μL；Split sampling, split ratio 10:1；Heating schedule：40 DEG C of initial temperature, keep 3
Min, 240 DEG C then are warming up to 3 DEG C/min speed, and keep 15 min.
Described Mass Spectrometer Method condition is as follows：Ionization mode：Electron bombardment ionization source（EI）；Transmission line temperature：240 ℃；Ion
Source temperature：230 ℃；Ionizing energy：70 eV；Solvent delay：5 min；Scanning range：30~350；Scan pattern：Total ion current
Scanning.
Embodiment 4
Menthol is a kind of essence commonly used in tobacco juice for electronic smoke, have the function that peppermint fragrance and have it is refrigerant, it is electric for improving
Sub- cigarette flue gas mouthfeel plays an important role.0.1% menthol is added in tobacco juice for electronic smoke, cigarette smoking is carried out with one channel smoke sucking machine,
The mL of pumping volume 20, puff duration 3s, Puffing interval is 180 s, and puffing profile is bell；By flue gas through dilute
Release（200 times of extension rate）After import ELPI, trap cigarette flue gas aerosol, trapping 50 with 12 grades of filter membranes being equipped in advance on ELPI
Mouth flue gas aerosol；Then every grade of filter membrane is respectively placed in 12 10mL vials, it is molten sequentially adds 30 mL dichloromethane
Liquid, ultrasonic extraction 25min, is removed, and extraction solution filters through 0.22 μm of organic phase mocromembrane, adds deuterated benzoic acid-d5 internal standard compounds
Solution, then GC-MS be measured, the concentration of menthol is obtained, so as to according to particle size range<0.03 μm、0.04μm、0.07
μm and 0.14 μm of ＞ drafting menthol distribution map, as shown in Figure 4.
Described gas chromatographic detection condition is as follows：
Chromatographic column：Elastic capillary-column, stationary phase are (5%- phenyl) -95% dimethyl polysiloxane, specification be the m of length 30 ×
The mm id of the internal diameter 0.25 × um df of thickness 0.25；Injector temperature：260 ℃；Carrier gas：Helium（The % of purity >=99.999）, it is permanent
Flow flow velocity：1.0 mL/min；Sample size：1 μL；Splitless injecting samples；Heating schedule：40 DEG C of initial temperature, 3 min are kept, then
240 DEG C are warming up to 3 DEG C/min speed, and keeps 15 min.
Described Mass Spectrometer Method condition is as follows：Ionization mode：Electron bombardment ionization source（EI）；Transmission line temperature：240 ℃；Ion
Source temperature：230 ℃；Ionizing energy：70 eV；Solvent delay：5 min；Scanning range：30~350；Scan pattern：Total ion current
Scanning.
Embodiment 5
Acetic acid is a kind of important acid in tobacco juice for electronic smoke, is played an important role for improving electronic cigarette gas port sense.Electronics
1% acetic acid is added in cigarette tobacco juice, carries out cigarette smoking, the mL of pumping volume 150 with one channel smoke sucking machine, puff duration is
5s, Puffing interval are 150 s, and puffing profile is square；By flue gas through dilution（7000 times of extension rate）After import ELPI,
Cigarette flue gas aerosol is trapped with the 12 grades of filter membranes equipped in advance on ELPI, traps 150 mouthfuls of flue gas aerosols；Then by every grade of filter membrane
It is respectively placed in 12 10mL vials, sequentially adds 50 mL methanol solutions, the min of ultrasonic extraction 15, remove, extraction solution warp
0.22 μm of organic phase mocromembrane filtering, adds deuterated valeric acid-D9 internal standard substance solutions, then GC-MS is measured, and obtains the dense of acetic acid
Degree, so as to according to particle size range<0.03 μm, 0.04~0.07 μm and ＞ 0.07 μm of drafting acetic acid distribution map, as shown in Figure 5.
Described gas chromatographic detection condition is as follows：
Chromatographic column：Elastic capillary-column, stationary phase are (50%- phenyl)-methyl polysiloxane, and specification is 30 m of length × internal diameter
The 0.25 mm id × um df of thickness 0.25；Injector temperature：250 ℃；Carrier gas：Helium（The % of purity >=99.999）, constant current stream
Speed：1.0 mL/min；Sample size：1 μL；Split sampling, split ratio 20:1；Heating schedule：40 DEG C of initial temperature, keep 3
Min, 240 DEG C then are warming up to 3 DEG C/min speed, and keep 15 min.
Described Mass Spectrometer Method condition is as follows：Ionization mode：Electron bombardment ionization source（EI）；Transmission line temperature：240 ℃；Ion
Source temperature：230 ℃；Ionizing energy：70 eV；Solvent delay：5 min；Scanning range：30~350；Scan pattern：Total ion current
Scanning.
General principle, principal character and the advantages of the present invention of the present invention has been shown and described above.The present invention is not by upper
The limitation of embodiment is stated, without departing from the spirit and scope of the present invention, various changes and modifications of the present invention are possible, this
A little changes and improvements all fall within the protetion scope of the claimed invention.The claimed scope of the invention is by appended claims
And its equivalent thereof.
Claims (4)
1. particle size distribution measuring method of a kind of electronic cigarette solution additive in flue gas aerosol, it is characterised in that including following
Step：
Step（1）Additive is made an addition in tobacco juice for electronic smoke by the 0.005 ~ 95% of tobacco juice weight；
Step（2）Electronic cigarette suction is carried out with one channel smoke sucking machine, and suction mode is the mL of pumping volume 15 ~ 250, puff duration
Time is 0.5 ~ 12 s, and Puffing interval is 4 ~ 200 s, and puffing profile is bell or square；
Step（3）Flue gas imports ELPI after diluting 100 ~ 10000 times, and flue gas gas is trapped with the 12 grades of filter membranes equipped in advance on ELPI
Colloidal sol, trap the aerosol of 5 ~ 400 mouthfuls of flue gases；
Step（4）Filter membrane after trapping is placed in 10 mL vials, 1 ~ 50 mL methanol or water is added or dichloromethane is molten
Liquid, 2 ~ 30min of ultrasonic extraction, extraction solution filter through 0.22 μm of aqueous phase or organic phase mocromembrane, add internal standard compound, then use gas phase
Chromatograph-mas spectrometer GC-MS is measured；
Described gas chromatographic detection condition is as follows：
Chromatographic column：Elastic capillary-column, specification are the mm id of 30 m of length × internal diameter 0.25 × um df of thickness 0.25；Injection port
Temperature：250~300℃；Carrier gas：The % of helium purity >=99.999, constant current flow velocity：1.0 mL/min；Sample size：1 μL；Do not shunt
Sample introduction or split sampling, split ratio 5:1~50:1；Heating schedule：40 DEG C of initial temperature, 3 min are kept, then with 3 DEG C/min
Speed be warming up to 240 DEG C, and keep 15 min；
Described Mass Spectrometer Method condition is as follows：Ionization mode：Electron bombardment ionization source（EI）；Transmission line temperature：240 ℃；Ion gun temperature
Degree：230 ℃；Ionizing energy：70 eV；Solvent delay：3 min；Scanning range：30~350；Scan pattern：Total ion current is swept
Retouch；
Step（5）According to the amount and particle diameter of additive on different-grain diameter, the grain size distribution of additive is drawn.
2. particle size distribution measuring side of the described electronic cigarette solution additive according to claim 1 in flue gas aerosol
Method, it is characterised in that：The step（4）Middle internal standard compound can according to the property of additive select property similar in material.
3. particle size distribution measuring side of the described electronic cigarette solution additive according to claim 1 in flue gas aerosol
Method, it is characterised in that：The step（4）The stationary phase of middle elastic capillary-column can be polyethylene glycol, (5%- phenyl) -95% diformazan
Based polysiloxane or (50%- phenyl)-methyl polysiloxane.
4. particle size distribution measuring side of the described electronic cigarette solution additive according to claim 1 in flue gas aerosol
Method, it is characterised in that：The step（5）Middle grain size distribution can draw 0.1 ~ 10 μm of particle diameter distribution.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710988300.9A CN107817195A (en) | 2017-10-21 | 2017-10-21 | Particle size distribution measuring method of the electronic cigarette solution additive in flue gas aerosol |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710988300.9A CN107817195A (en) | 2017-10-21 | 2017-10-21 | Particle size distribution measuring method of the electronic cigarette solution additive in flue gas aerosol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107817195A true CN107817195A (en) | 2018-03-20 |
Family
ID=61608582
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710988300.9A Pending CN107817195A (en) | 2017-10-21 | 2017-10-21 | Particle size distribution measuring method of the electronic cigarette solution additive in flue gas aerosol |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107817195A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113720937A (en) * | 2021-08-30 | 2021-11-30 | 深圳市真味生物科技有限公司 | Method for measuring content of cooling agent in electronic smoke sol |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101105480A (en) * | 2007-08-21 | 2008-01-16 | 中国烟草总公司郑州烟草研究院 | Cigarette main flume volatile organic compound ingredient determination method |
| CN104614465A (en) * | 2015-02-16 | 2015-05-13 | 国家烟草质量监督检验中心 | Method for simultaneously measuring content of nicotine, 1,2-propylene glycol and glycerol in electronic smoke sol |
| CN104698117A (en) * | 2015-03-20 | 2015-06-10 | 中国烟草总公司郑州烟草研究院 | Simultaneous determination method for nicotine, 1,2-propylene glycol and glycerol in electronic cigarette smoke |
| CN105372354A (en) * | 2015-12-25 | 2016-03-02 | 国家烟草质量监督检验中心 | Method for detecting nicotine and secondary alkaloids in nicotine liquid and main stream smoke of electronic cigarette |
| CN105842378A (en) * | 2016-05-18 | 2016-08-10 | 云南中烟工业有限责任公司 | Determination method of aroma components in electronic cigarette aerosol |
-
2017
- 2017-10-21 CN CN201710988300.9A patent/CN107817195A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101105480A (en) * | 2007-08-21 | 2008-01-16 | 中国烟草总公司郑州烟草研究院 | Cigarette main flume volatile organic compound ingredient determination method |
| CN104614465A (en) * | 2015-02-16 | 2015-05-13 | 国家烟草质量监督检验中心 | Method for simultaneously measuring content of nicotine, 1,2-propylene glycol and glycerol in electronic smoke sol |
| CN104698117A (en) * | 2015-03-20 | 2015-06-10 | 中国烟草总公司郑州烟草研究院 | Simultaneous determination method for nicotine, 1,2-propylene glycol and glycerol in electronic cigarette smoke |
| CN105372354A (en) * | 2015-12-25 | 2016-03-02 | 国家烟草质量监督检验中心 | Method for detecting nicotine and secondary alkaloids in nicotine liquid and main stream smoke of electronic cigarette |
| CN105842378A (en) * | 2016-05-18 | 2016-08-10 | 云南中烟工业有限责任公司 | Determination method of aroma components in electronic cigarette aerosol |
Non-Patent Citations (1)
| Title |
|---|
| 孔浩辉，吴君章，沈光林: "ELPI设定条件对卷烟主流烟气气溶胶检测结果的影响", 《烟草科技》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113720937A (en) * | 2021-08-30 | 2021-11-30 | 深圳市真味生物科技有限公司 | Method for measuring content of cooling agent in electronic smoke sol |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Gerloff et al. | Inflammatory response and barrier dysfunction by different e-cigarette flavoring chemicals identified by gas chromatography–mass spectrometry in e-liquids and e-vapors on human lung epithelial cells and fibroblasts | |
| CN105842378B (en) | The assay method of flavor component in a kind of electronics smoke sol | |
| CN104698117B (en) | Assay method while nicotine, 1,2-propylene glycol and glycerol in a kind of electronic cigarette flue gas | |
| KR20170065639A (en) | Solution comprising nicotine in unprotonated from and protonated form | |
| JP7372979B2 (en) | Water-based flavor liquid for electronic cigarettes | |
| CN105021741B (en) | Analytical method and apparatus for bionic absorption liquid used for main stream smoke | |
| CN110393307A (en) | A kind of smokeless tobacco tar and preparation method thereof | |
| CN113038842B (en) | Aerosol formulation | |
| UA127838C2 (en) | Aerosolisable formulation | |
| CN110338451A (en) | A kind of preparation method of tobacco juice for electronic smoke | |
| CN108125277A (en) | A kind of electronic cigarette and preparation method thereof | |
| TW202034799A (en) | Non-combustion type heating smoking article and method for using the same, and non-combustion type heating smoking system | |
| UA127723C2 (en) | Aerosolisable formulation | |
| CN104783323B (en) | A kind of tobacco juice for electronic smoke containing Dry distillated flavor | |
| CN107817195A (en) | Particle size distribution measuring method of the electronic cigarette solution additive in flue gas aerosol | |
| CN108548880A (en) | The assay method of Multiple components in a kind of electronic cigarette flue gas | |
| CN101323816A (en) | White tea essential oil, preparation and use thereof | |
| Lu et al. | Progress in quantification of nicotine content and form distribution in electronic cigarette liquids and aerosols | |
| CN108088946A (en) | A kind of cigarette flavors additive distribution determination method under flue gas different-grain diameter | |
| CN108037045A (en) | Heat the assay method that cigarette flavors are distributed in different-grain diameter flue gas aerosol that do not burn | |
| O’Connell et al. | An experimental method to determine the concentration of nicotine in exhaled breath and its retention rate following use of an electronic cigarette | |
| CN108185539A (en) | Electronic cigarette that a kind of aesthetic quality is improved and preparation method thereof | |
| CN210726685U (en) | Aerosol-generating article | |
| RU2785974C2 (en) | Aerosolising composition | |
| CN108294357A (en) | A kind of electronic cigarette that aesthetic quality gets a promotion and its manufacturing method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |