CN107814034B - Low-cost long-time-effect medicine cold chain insulation can - Google Patents
Low-cost long-time-effect medicine cold chain insulation can Download PDFInfo
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- CN107814034B CN107814034B CN201711220499.7A CN201711220499A CN107814034B CN 107814034 B CN107814034 B CN 107814034B CN 201711220499 A CN201711220499 A CN 201711220499A CN 107814034 B CN107814034 B CN 107814034B
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- box
- wall
- case
- phase change
- heat insulation
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- 238000009413 insulation Methods 0.000 title claims abstract description 33
- 239000003814 drug Substances 0.000 title claims abstract description 13
- 230000008859 change Effects 0.000 claims abstract description 37
- 239000012774 insulation material Substances 0.000 claims abstract description 30
- 239000011232 storage material Substances 0.000 claims abstract description 27
- 238000001816 cooling Methods 0.000 claims abstract description 11
- 239000000463 material Substances 0.000 claims description 63
- YCOZIPAWZNQLMR-UHFFFAOYSA-N heptane - octane Natural products CCCCCCCCCCCCCCC YCOZIPAWZNQLMR-UHFFFAOYSA-N 0.000 claims description 21
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 14
- CJBFZKZYIPBBTO-UHFFFAOYSA-N isotetradecane Natural products CCCCCCCCCCCC(C)C CJBFZKZYIPBBTO-UHFFFAOYSA-N 0.000 claims description 14
- BGHCVCJVXZWKCC-UHFFFAOYSA-N tetradecane Chemical compound CCCCCCCCCCCCCC BGHCVCJVXZWKCC-UHFFFAOYSA-N 0.000 claims description 14
- IIYFAKIEWZDVMP-UHFFFAOYSA-N tridecane Chemical compound CCCCCCCCCCCCC IIYFAKIEWZDVMP-UHFFFAOYSA-N 0.000 claims description 14
- 239000004033 plastic Substances 0.000 claims description 13
- 229920003023 plastic Polymers 0.000 claims description 13
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 claims description 12
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 12
- 238000002156 mixing Methods 0.000 claims description 12
- 238000009825 accumulation Methods 0.000 claims description 10
- 239000004794 expanded polystyrene Substances 0.000 claims description 9
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 8
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 7
- 239000001110 calcium chloride Substances 0.000 claims description 7
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 7
- SNRUBQQJIBEYMU-UHFFFAOYSA-N dodecane Chemical compound CCCCCCCCCCCC SNRUBQQJIBEYMU-UHFFFAOYSA-N 0.000 claims description 7
- 229940094933 n-dodecane Drugs 0.000 claims description 7
- 239000011780 sodium chloride Substances 0.000 claims description 7
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims description 6
- 239000000440 bentonite Substances 0.000 claims description 6
- 235000012216 bentonite Nutrition 0.000 claims description 6
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 claims description 6
- 239000011810 insulating material Substances 0.000 claims description 6
- 229910001629 magnesium chloride Inorganic materials 0.000 claims description 6
- 239000000377 silicon dioxide Substances 0.000 claims description 6
- 235000012239 silicon dioxide Nutrition 0.000 claims description 6
- 229910052938 sodium sulfate Inorganic materials 0.000 claims description 6
- 235000011152 sodium sulphate Nutrition 0.000 claims description 6
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims description 5
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 5
- 229910021538 borax Inorganic materials 0.000 claims description 5
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 5
- UQGFMSUEHSUPRD-UHFFFAOYSA-N disodium;3,7-dioxido-2,4,6,8,9-pentaoxa-1,3,5,7-tetraborabicyclo[3.3.1]nonane Chemical compound [Na+].[Na+].O1B([O-])OB2OB([O-])OB1O2 UQGFMSUEHSUPRD-UHFFFAOYSA-N 0.000 claims description 5
- 239000000661 sodium alginate Substances 0.000 claims description 5
- 235000010413 sodium alginate Nutrition 0.000 claims description 5
- 229940005550 sodium alginate Drugs 0.000 claims description 5
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 5
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 5
- 239000004328 sodium tetraborate Substances 0.000 claims description 5
- 235000010339 sodium tetraborate Nutrition 0.000 claims description 5
- PODWXQQNRWNDGD-UHFFFAOYSA-L sodium thiosulfate pentahydrate Chemical compound O.O.O.O.O.[Na+].[Na+].[O-]S([S-])(=O)=O PODWXQQNRWNDGD-UHFFFAOYSA-L 0.000 claims description 5
- BDKLKNJTMLIAFE-UHFFFAOYSA-N 2-(3-fluorophenyl)-1,3-oxazole-4-carbaldehyde Chemical compound FC1=CC=CC(C=2OC=C(C=O)N=2)=C1 BDKLKNJTMLIAFE-UHFFFAOYSA-N 0.000 claims description 4
- 239000002250 absorbent Substances 0.000 claims description 4
- 230000002745 absorbent Effects 0.000 claims description 4
- 239000001103 potassium chloride Substances 0.000 claims description 4
- 235000011164 potassium chloride Nutrition 0.000 claims description 4
- 239000011347 resin Substances 0.000 claims description 4
- 229920005989 resin Polymers 0.000 claims description 4
- 235000017281 sodium acetate Nutrition 0.000 claims description 4
- 229940087562 sodium acetate trihydrate Drugs 0.000 claims description 4
- 235000011148 calcium chloride Nutrition 0.000 claims description 3
- 230000032683 aging Effects 0.000 claims description 2
- 229910000280 sodium bentonite Inorganic materials 0.000 claims description 2
- 238000004321 preservation Methods 0.000 abstract description 15
- 238000002360 preparation method Methods 0.000 description 9
- 239000000047 product Substances 0.000 description 6
- 238000005187 foaming Methods 0.000 description 5
- 238000002844 melting Methods 0.000 description 5
- 230000008018 melting Effects 0.000 description 5
- 229910000278 bentonite Inorganic materials 0.000 description 4
- 239000010410 layer Substances 0.000 description 4
- 235000013399 edible fruits Nutrition 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000012782 phase change material Substances 0.000 description 3
- 235000013311 vegetables Nutrition 0.000 description 3
- 229940079593 drug Drugs 0.000 description 2
- 238000004146 energy storage Methods 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 230000009545 invasion Effects 0.000 description 2
- -1 polypropylene Polymers 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 239000002356 single layer Substances 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 150000001335 aliphatic alkanes Chemical class 0.000 description 1
- 239000010425 asbestos Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003124 biologic agent Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 229920006351 engineering plastic Polymers 0.000 description 1
- 239000000374 eutectic mixture Substances 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- QWXYZCJEXYQNEI-OSZHWHEXSA-N intermediate I Chemical compound COC(=O)[C@@]1(C=O)[C@H]2CC=[N+](C\C2=C\C)CCc2c1[nH]c1ccccc21 QWXYZCJEXYQNEI-OSZHWHEXSA-N 0.000 description 1
- 239000013067 intermediate product Substances 0.000 description 1
- 239000011490 mineral wool Substances 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000002985 plastic film Substances 0.000 description 1
- 229920006255 plastic film Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 229910052895 riebeckite Inorganic materials 0.000 description 1
- 238000001175 rotational moulding Methods 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000004781 supercooling Methods 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D11/00—Containers having bodies formed by interconnecting or uniting two or more rigid, or substantially rigid, components made wholly or mainly of plastics material
- B65D11/16—Containers having bodies formed by interconnecting or uniting two or more rigid, or substantially rigid, components made wholly or mainly of plastics material with double walls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D43/00—Lids or covers for rigid or semi-rigid containers
- B65D43/02—Removable lids or covers
- B65D43/0202—Removable lids or covers without integral tamper element
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/18—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/38—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents with thermal insulation
- B65D81/3813—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents with thermal insulation rigid container being in the form of a box, tray or like container
- B65D81/3823—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents with thermal insulation rigid container being in the form of a box, tray or like container formed of different materials, e.g. laminated or foam filling between walls
Abstract
The invention discloses a low-cost long-aging medical cold chain insulation box which comprises a box body and a box cover, wherein the box body comprises a box bottom and box walls, the box walls comprise an outer box wall (1), a middle box wall (2) and an inner box wall (3), a heat insulation cavity is formed between the outer box wall (1) and the middle box wall (2), a cooling cavity is formed between the middle box wall (2) and the inner box wall (3), the box cover comprises a first box cover (4), a second box cover (5) and a third box cover (6) from outside to inside, the first box cover is covered with the top of the outer box wall, the second box cover covers the top of the middle box wall and seals the heat insulation cavity (8), and the third box cover covers the top of the inner box wall and seals the cooling cavity (9). The invention can greatly improve the temperature control capability and the heat preservation performance through improving the structures of the box body and the box cover and combining and collocating the heat insulation material and the phase change cold storage material, so that the invention can be directly applied to the high-added-value medicine cold chain transportation.
Description
Technical Field
The invention relates to an insulation can, in particular to a low-cost long-aging medical cold chain insulation can.
Background
The heat insulation materials with relatively low price in the market at present mainly comprise expanded polypropylene (EPP) or Expanded Polystyrene (EPS), and the heat insulation boxes have the advantages of mature foaming process, high yield, low price and the like, so the heat insulation boxes are favored by the market. However, the heat preservation performance is limited, so that the heat preservation material is generally only applied to short-distance fresh vegetable and fruit transportation.
The EPP or EPS foaming insulation boxes currently have the following technical defects:
1. the thermal conductivity is too high, resulting in poor overall insulation performance. The heat preservation can only be carried out for not more than 12 hours according to the requirement of 35 ℃ of continuous limit, can not be applied to trans-province or trans-national transportation, and can only be used for transporting fresh vegetables and fruits and other products with low temperature requirements in a short distance.
2. The box wall and the box cover are of single-layer structure, and the structural strength and the heat preservation performance are poor.
3. Fresh vegetables and fruits belong to low added value products, the price of transporting the products is greatly limited, the single package cannot exceed 150 yuan, and in order to control the cost, the configuration of the incubator is basically that the incubator is added with a plurality of boxes of ice cubes for transportation, and the temperature control is very poor.
Therefore, the incubator is not suitable for being applied to the transportation of products with high added values, such as biological agents, vaccines, medicines and the like, which have strict requirements on temperature, and the existing incubator structure which can be applied to the products such as medicines and the like, is basically made of plastic boxes by a rotational molding process, and has the advantages of high strength, large volume, heavy weight and very low effective utilization rate. And the price is very high, and the general medicine enterprise is hardly accepted.
Disclosure of Invention
The invention aims to solve the problems of poor heat preservation performance of the existing EPP or EPS foaming heat preservation box, large volume, heavy weight and high cost of an engineering plastic box, and provides a low-cost long-aging medical cold chain heat preservation box.
The technical scheme adopted for solving the technical problems is as follows:
the utility model provides a long ageing medicine cold chain insulation can of low cost, includes box and case lid, the box includes bottom of the case and case wall, the case wall includes outer case wall 1, well case wall 2 and interior case wall 3, forms thermal-insulated chamber 8 between outer case wall 1 and the well case wall 2, forms between well case wall 2 and the interior case wall 3 and supplies cold chamber 9, the case lid includes first case lid 4, second case lid 5 and third case lid 6 from outside to inside, and first case lid closes with outer case wall top lid, and the second case lid covers in well case wall top and seals thermal-insulated chamber, and the third case lid covers in interior case wall top and seals and supplies cold chamber.
The invention is different from the traditional EPP or EPS foaming insulation box with a single-layer structure, the box wall is of a three-layer structure, a heat insulation cavity and a cooling cavity are formed between the box walls, and the heat insulation cavity is filled with heat insulation materials to effectively prevent the invasion of external heat and the dissipation of internal cold; the cold supply cavity is filled with phase change cold storage materials, so that cold quantity can be stably provided for a long time; in addition, the case cover of the invention has three matched layers from the inner layer to the outer layer to seal so as to effectively prevent the invasion of external heat and the dissipation of internal cold. Through the improvement of the structure, the temperature control capability and the heat preservation performance can be greatly improved, so that the invention can be directly applied to the medicine cold chain transportation with high added value.
In addition, the groove for containing heat insulation materials is formed in the top surface of the second box cover, the groove for containing phase change cold accumulation materials is formed in the top surface of the third box cover, and the heat insulation materials and the phase change cold accumulation materials can be filled in the grooves respectively, so that heat insulation and cooling are formed at the box cover part, a heat insulation and cooling surrounding environment is formed by matching the heat insulation cavity and the cooling cavity, and the temperature control capability and the heat preservation performance can be greatly improved.
Preferably, a groove 7 for containing heat insulation material is arranged on the top surface of the second box cover, and the heat insulation material is filled in the groove.
Preferably, a groove for containing the phase change cold storage material is arranged on the top surface of the third case cover, and the groove is filled with the phase change cold storage material.
Preferably, the heat insulation cavity is filled with heat insulation materials.
Preferably, the heat insulation material is packaged by a plastic bag or a plastic box, and is prepared by mixing 30-55% of material A, 3-9.5% of material B, 0.2-6.6% of material C, 0.4-3.5% of material D and 30-60% of water according to mass percentage;
the material A is one or more of calcium chloride, sodium sulfate, sodium acetate trihydrate and sodium thiosulfate pentahydrate;
the material B is selected from sodium chloride, potassium chloride one or more of magnesium chloride;
the material C is one or more selected from sodium tetraborate, bentonite and silicon dioxide;
the material D is one or more selected from sodium alginate, super absorbent resin and sodium carboxymethyl cellulose.
Aiming at the problem of poor heat preservation performance of the existing EPP or EPS foaming heat preservation box, the invention develops a specific heat insulation material which is essentially a phase change energy storage material with the melting point of about 25 ℃. The heat insulation material can absorb heat or cold energy immersed in the outside, provides a stable environment for heat preservation of the phase change cold storage material in the inside, and can further prevent the dissipation of the cold energy released by the phase change cold storage material. The material A is used as a main component, the material B is used for adjusting the phase change temperature, and the material C is a crystal nucleus agent, so that the crystallization efficiency is improved, and the phase change efficiency is improved; material D is a stabilizer.
Preferably, the cooling cavity is filled with a phase change cold storage material.
Preferably, the phase change cold storage material is encapsulated by a plastic bag or a plastic box.
Preferably, the phase change cold storage material is prepared by mixing the following components in percentage by weight: 88.5 to 91.8 percent of n-tetradecane, 4 to 5 percent of n-dodecane, 2 to 3 percent of n-tridecane, 2 to 3 percent of n-pentadecane and 0.2 to 0.5 percent of isotetradecane.
According to the invention, different alkanes with the carbon number of 12-15 are subjected to specific proportioning and combination, so that a phase change material with certain specific cold accumulation performance is formed, the melting point (phase change temperature point) of the material is 2-3 ℃, and the medicine temperature is ensured to be maintained within an effective range of more than 0 ℃ and less than 5 ℃ in the transportation process; and the phase change material has high melting enthalpy, low supercooling degree and good circulation stability.
Preferably, the materials of the box body and the box cover are both expanded polystyrene.
Preferably, the heights of the outer tank wall, the middle tank wall and the inner tank wall decrease in sequence.
The beneficial effects of the invention are as follows: through improvement of the box body and box cover structure and combination and collocation of the heat insulation material and the phase change cold storage material, the temperature control capability and the heat preservation performance can be greatly improved, so that the invention can be directly applied to high-added-value medicine cold chain transportation.
Drawings
FIG. 1 is a schematic illustration of the present invention a main body structure schematic diagram.
Fig. 2 is a cross-sectional view of the present invention.
Fig. 3 is a top view of the case of the present invention.
In the figure: 1. the refrigerator comprises an outer tank wall 2, a middle tank wall 3, an inner tank wall 4, a first tank cover 5, a second tank cover 6, a third tank cover 7, a groove 8, a heat insulation cavity 9 and a cooling cavity.
Detailed Description
The technical scheme of the invention is further specifically described below through specific embodiments and with reference to the accompanying drawings.
Examples:
the low-cost long-aging medical cold chain insulation box shown in fig. 1 comprises a box body and a box cover, wherein the box body and the box cover are made of expanded polystyrene, the box body comprises a box bottom and box walls, the box walls comprise an outer box wall 1, a middle box wall 2 and an inner box wall 3, a heat insulation cavity 8 is formed between the outer box wall 1 and the middle box wall 2, heat insulation materials are filled in the heat insulation cavity, and the heat insulation materials are wrapped by plastic films and are convenient to replace; a cold supply cavity 9 is formed between the middle tank wall 2 and the inner tank wall 3, phase change cold storage materials are filled in the cold supply cavity, the box cover comprises a first box cover 4, a second box cover 5 and a third box cover 6 from outside to inside, the first box cover is covered with the top of the outer box wall, the second case cover covers the top of the middle case wall and seals the heat insulation cavity, the outer side edge of the second case cover is connected with the inner wall of the outer case wall, the third case cover covers the top of the inner case wall and seals the cold supply cavity, and the outer side edge of the third case cover is connected with the inner wall of the middle case wall. The top surface of the second case cover is provided with a groove 7 for containing heat insulation materials, the heat insulation materials are filled in the groove of the second case cover, the top surface of the third case cover is provided with a groove 7 for containing phase change cold accumulation materials, and the groove of the third case cover is filled with phase change cold accumulation materials. The heat insulation materials used above are packaged by plastic bags or plastic boxes, so that the heat insulation materials are convenient to replace; the used phase change cold storage material (or phase change energy storage material) is packaged by a plastic bag or a plastic box, is convenient to recharge after being used, and is recycled.
The heat insulating material can be made of the existing glass fiber, asbestos, rock wool, silicate and the like, and more preferably, the heat insulating material specifically designed by the inventor is adopted:
the heat insulation material is prepared by mixing 30-55% of material A, 3-9.5% of material B, 0.2-6.6% of material C, 0.4-3.5% of material D and 30-60% of water according to mass percentage;
the material A is one or more of calcium chloride, sodium sulfate, sodium acetate trihydrate and sodium thiosulfate pentahydrate;
the material B is one or more selected from sodium chloride, potassium chloride and magnesium chloride;
the material C is selected from sodium tetraborate, bentonite in silicon dioxide one or more of them;
the material D is one or more selected from sodium alginate, super absorbent resin and sodium carboxymethyl cellulose.
One specific preparation method is as follows:
intermediate product one: 20g of sodium chloride (material B), 20g of potassium chloride (material B), 2g of sodium tetraborate (material C), 1g of bentonite (material C) and 250g of water are weighed, placed in a 2000ml beaker, heated to 40 ℃, and stirred for 30 minutes.
Intermediate II: 500g of calcium chloride (material A) are weighed and added 250g of the mixture was stirred for 5 minutes.
Pouring the intermediate II into the intermediate I, adding 3g of sodium alginate (material D), and stirring 2g of sodium carboxymethylcellulose (material D) at 40 ℃ for 30 minutes to prepare the heat insulation material.
The phase-change cold-storage material can be the existing commercial (such as the material with the melting point of 0-8 ℃) phase-change material or the phase-change cold-storage material disclosed in the prior document CN 103242806A, and more preferably the material specifically developed by the invention: the phase change cold accumulation material is prepared by mixing the following components in percentage by weight: 88.5 to 91.8 percent of n-tetradecane, 4 to 5 percent of n-dodecane, 2 to 3 percent of n-tridecane, 2 to 3 percent of n-pentadecane and 0.2 to 0.5 percent of isotetradecane.
Preparation of insulation material example 1:
the heat insulation material is prepared by mixing 40% of material A (calcium chloride, sodium sulfate, calcium chloride: sodium sulfate mass ratio=3:1), 5% of material B (magnesium chloride), 3% of material C (silicon dioxide), 2% of material D (sodium alginate) and 50% of water according to mass percentage.
Preparation methods refer to the examples section.
Preparation example 2 of heat insulating material:
the heat insulation material is prepared by mixing 49% of material A (sodium sulfate, sodium acetate trihydrate, sodium thiosulfate pentahydrate, mass ratio of sodium thiosulfate pentahydrate=2:1:1), 4.5% of material B (sodium chloride, magnesium chloride, mass ratio of sodium chloride to magnesium chloride=1:1), 0.7% of material C (sodium tetraborate), 0.8% of material D (super absorbent resin, commercially available) and 45% of water according to mass percentage.
Preparation example 3 of heat insulating material:
the heat insulation material is prepared by mixing 46% of material A (calcium chloride), 4% of material B (sodium chloride), 0.4% of material C (bentonite, silicon dioxide, bentonite: silicon dioxide mass ratio=2:1), 0.6% of material D (sodium carboxymethyl cellulose) and 49% of water according to mass percentage.
Phase change cold storage material preparation example 1:
the phase change cold storage material is prepared by mixing the following components in percentage by weight: 88.5% of n-tetradecane, 5% of n-dodecane, 3% of n-tridecane, 3% of n-pentadecane and 0.5% of isotetradecane.
The preparation method comprises the following steps: n-tetradecane, n-dodecane, n-tridecane, n-pentadecane and isotetradecane are respectively placed in different containers, respectively preheated to 35 ℃, the five preheated materials are sequentially poured into a 500ml three-neck flask, and the mixed solution is stirred and reacts for 1 hour under the conditions of constant temperature water bath at 35 ℃ and rotating speed of 200-300 r/min to form a eutectic mixture. After the reaction is finished, naturally cooling to room temperature environment to obtain the phase change cold storage material with the melting point of 2-3 ℃ which can be used for medicine cold chain transportation.
Phase change cold storage material preparation example 2:
the phase change cold storage material is prepared by mixing the following components in percentage by weight: 91.8% of n-tetradecane, 4% of n-dodecane, 2% of n-tridecane, 2% of n-pentadecane and 0.2% of isotetradecane.
Phase change cold storage material preparation example 3:
the phase change cold storage material is prepared by mixing the following components in percentage by weight: 91% of n-tetradecane, 4% of n-dodecane, 2.5% of n-tridecane, 2.2% of n-pentadecane and 0.3% of isotetradecane.
The operation method of the invention is as follows: the heat insulation material and the phase change cold accumulation material are placed in an environment of minus 20 ℃ for 12 hours, the heat insulation material is taken out after the heat insulation material is completed, placed in an environment of 15-25 ℃ for 1 hour, and the phase change cold accumulation material is placed in an environment of 2-8 ℃ for 1 hour and then is placed in a box body.
The invention can meet the requirement of heat preservation for more than 48 hours in the environment of 43 ℃ of continuous limit or the environment of-20 ℃ of continuous limit low temperature.
Compared with the prior EPS insulation can, the invention can greatly improve the temperature control capability and the insulation performance, and can be directly applied to the medicine cold chain transportation with high added value.
Meanwhile, the adopted heat insulation materials and the phase change cold storage material raw materials are mature products in the market, the price is low, the cost of the heat insulation box can be effectively controlled, and compared with a medical cold chain heat insulation box sold in the market, the price of the heat insulation box is reduced by more than 60%.
The above-described embodiment is only a preferred embodiment of the present invention, and is not limited in any way, and other variations and modifications may be made without departing from the technical aspects set forth in the claims.
Claims (5)
1. The utility model provides a low-cost long-acting medicine cold chain insulation can, includes box and case lid, its characterized in that, the box includes bottom of the case and case wall, the case wall includes outer case wall (1), well case wall (2) and interior case wall (3), form thermal-insulated chamber (8) between outer case wall (1) and well case wall (2), form cooling chamber (9) between well case wall (2) and interior case wall (3), the case lid includes first case lid (4), second case lid (5) and third case lid (6) from outside to inside, and first case lid and outer case wall top lid are closed, and the second case lid covers in well case wall top and seals thermal-insulated chamber, and the third case lid covers in interior case wall top and seals cooling chamber;
the heat insulation cavity is filled with heat insulation materials; the heat insulation material is packaged by a plastic bag or a plastic box and is prepared by mixing, by mass, 30-55% of a material A, 3-9.5% of a material B, 0.2-6.6% of a material C, 0.4-3.5% of a material D and 30-60% of water;
the material A is one or more of calcium chloride, sodium sulfate, sodium acetate trihydrate and sodium thiosulfate pentahydrate;
the material B is one or more selected from sodium chloride, potassium chloride and magnesium chloride;
the material C is one or more selected from sodium tetraborate, bentonite and silicon dioxide;
the material D is one or more selected from sodium alginate, super absorbent resin and sodium carboxymethyl cellulose;
the cold supply cavity is filled with a phase change cold storage material; the phase change cold accumulation material is encapsulated by a plastic bag or a plastic box;
the phase change cold accumulation material is prepared by mixing the following components in percentage by weight: 88.5 to 91.8 percent of n-tetradecane, 4 to 5 percent of n-dodecane, 2 to 3 percent of n-tridecane, 2 to 3 percent of n-pentadecane and 0.2 to 0.5 percent of isotetradecane.
2. The low-cost long-aging pharmaceutical cold chain incubator according to claim 1, wherein the top surface of the second case cover is provided with a groove (7) for containing heat insulating material, and the groove is filled with heat insulating material.
3. The low-cost long-acting medical cold chain insulation can of claim 1, wherein the top surface of the third can cover is provided with a groove for containing phase change cold storage materials, and the groove is filled with the phase change cold storage materials.
4. The low-cost long-acting medical cold chain insulation can of claim 1, wherein the material of the can body and the can cover are both expanded polystyrene.
5. The low cost long aging pharmaceutical cold chain incubator of claim 1, wherein the heights of the outer, middle and inner walls decrease in sequence.
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| CN110884756A (en) * | 2019-11-18 | 2020-03-17 | 中国水利水电科学研究院 | Box is preserved to open-air sampling reagent |
| CN113637460B (en) * | 2021-08-26 | 2023-10-13 | 杭州鲁尔新材料科技有限公司 | Accurate temperature control phase change material for drug short-distance transportation and folding cold storage bag using same |
| CN114381236B (en) * | 2021-12-15 | 2024-02-02 | 杭州鲁尔新材料科技有限公司 | High-viscosity phase-change material easy to fill |
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