CN107812142A - 一种可有效治疗痛风的丸剂药物及制备方法 - Google Patents
一种可有效治疗痛风的丸剂药物及制备方法 Download PDFInfo
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Abstract
本发明属于中药制剂领域,目的是根据中医治疗痛风的认识机理而提供一种可有效治疗痛风的丸剂药物,所述药物的各个组分及其质量份比如下:威灵仙60~120g、海金沙60~160g、厚朴30~120g、羌活30~120g、五味子20~70g、甘草30~130g、白头翁100~160g、川朴30~120g、金银花150~300g、川贝母30~120g、鸡内金30~120g、砂仁30~70g、石斛60~160g、岗梅根150~350g;本发明提供的药物是一个很好的中药组方。
Description
技术领域
本发明属于中药制剂领域,具体涉及一种可有效治疗痛风的丸剂药物,特别是供痛风患者使用的丸剂药物及制备方法的领域。
背景技术
据相关文献显示:痛风是由单钠尿酸盐(MSU)沉积所致的晶体相关性关节病,与嘌呤代谢紊乱和(或)尿酸排泄减少所致的高尿酸血症直接相关,特指急性特征性关节炎和慢性痛风石疾病,主要包括急性发作性关节炎、痛风石形成、痛风石性慢性关节炎、尿酸盐肾病和尿酸性尿路结石,重者可出现关节残疾和肾功能不全。痛风常伴腹型肥胖、高脂血症、高血压、2型糖尿病及心血管病等表现。
那么,就如何找到一种可有效治疗痛风的中药组合物,是本领域技术人员亟待要解决的问题。
发明内容
随着我国中医中药学的不断发展,在治疗痛风上,人们逐渐意识到了中医治疗痛风的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗痛风的现状,本发明的目的是在于提供一种可有效治疗痛风的丸剂药物,以解决痛风患者早日恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及质量份比,可有效治疗上述痛风。
为达到上述发明的目的,本发明所采用的技术方案为:提供一种可有效治疗痛风的丸剂药物及制备方法,其特征在于,所述药物的各个组分及质量份比如下所示:
威灵仙60~120g、海金沙60~160g、厚朴30~120g、羌活30~120g、五味子20~70g、甘草30~130g、白头翁100~160g、川朴30~120g、金银花150~300g、川贝母30~120g、鸡内金30~120g、砂仁30~70g、石斛60~160g、岗梅根150~350g,辅料:淀粉适量。
一种可有效治疗痛风的丸剂药物及制备方法,其特征在于,所述药物的各个组分及质量份比如下所示:
威灵仙70~105g、海金沙70~140g、厚朴38~105g、羌活38~105g、五味子23~60g、甘草38~115g、白头翁115~140g、川朴38~105g、金银花180~260g、川贝母38~105g、鸡内金38~105g、砂仁38~60g、石斛70~140g、岗梅根180~310g,辅料:淀粉适量。
一种可有效治疗痛风的丸剂药物及制备方法,其特征在于,所述药物的各个组分及质量份比如下所示:
威灵仙95g、海金沙120g、厚朴95g、羌活95g、五味子52g、甘草100g、白头翁120g、川朴95g、金银花230g、川贝母95g、鸡内金95g、砂仁52g、石斛120g、岗梅根260g,辅料:淀粉适量。
一种可有效治疗痛风的丸剂药物及制备方法,其特征在于,所述方法包括如下步骤制备而成:
A、除淀粉外,将上述原料中药拣去杂质、粉尘及干燥后,按照质量份比共研为极细末待用;
B、按照传统制备中药水丸剂的方法,将研磨好的极细末药物和淀粉过筛后,放入药器中混合拌均,然后制备成水丸剂(其水丸的粒度为:3.9mm~4.0mm),进而烘干,分装密封即可。
一种可有效治疗痛风的丸剂药物及制备方法,其特征在于,所述服用方法为:将制备好的水丸剂药物以每日三次服用,早中晚各服一次,给药量5.5g /次,温开水送服。15天为一个疗程,治疗3~6个疗程,检查:血尿酸降至正常范围。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
威灵仙,性味:味辛、咸、性温,具有有祛风湿、通经络之功效,用于治疗风湿痹痛、肢体麻木、筋脉拘挛、屈伸不利;
海金沙,性味:味甘、咸、性寒,具有清利湿热、通淋止痛之功效,用于治疗热淋、石淋、血淋、膏淋、尿道涩痛;
厚朴,性味:味苦、辛,性温,具有燥湿消痰、下气除满之功效,用于治疗湿滞伤中、脘痞吐泻、食积气滞、腹胀便秘、痰饮喘咳;
羌活,味辛、苦、性温,具有解表散寒、祛风胜湿、止痛之功效,用于治疗风寒感冒、风寒湿痹、项强筋急、骨节酸疼、风水浮肿、痈疽疮毒等症;
五味子,性味:酸、甘、温,具有收敛固涩、益气生津、补肾宁心之功效,用于治疗久嗽虚喘、梦遗滑精、遗尿尿频、久泻不止、自汗、盗汗、津伤口渴、短气脉虚、内热消渴、心悸失眠;
甘草,性味:甘、平,具有益气补中、缓急止痛、润肺止咳、泻火解毒、调和诸药之功效,用于治疗倦怠食少、肌瘦面黄、心悸气短、腹痛便溏、四肢挛急疼痛、脏躁、咳嗽气喘、咽喉肿痛、痈疮肿痛、小儿胎毒及药物、食物中毒;
白头翁,性味:苦、寒,具有清热解毒、凉血止痢之功效,用于治疗热毒血痢、阴痒带下;
川朴,性味:苦、辛、性温,具有行气消积、燥湿除满、降逆平喘之功效,用于治疗食积气滞、腹胀便秘、湿阻中焦、脘痞吐泻、痰壅气逆、胸满喘咳;
金银花,性味:甘、寒,具有清热解毒之功效,用于治疗温病发热、热毒血痢、痈肿疔疮、喉痹及多种感染性疾病;
川贝母,性味:性凉、甘平,具有润肺止咳化痰平喘、清热化痰之功效,用于治疗肺热燥咳、干咳少痰、阴虚劳嗽、痰中带血、瘰疬、乳痈、肺痈等症;
鸡内金,性味:甘、平,具有健胃消食、涩精止遗、通淋化石之功效,用于治疗食积不消、呕吐泻痢、小儿疳积、遗尿、遗精、石淋涩痛、胆胀胁痛等症;
砂仁,性味:味辛、性温,具有化湿开胃、温脾止泻、理气安胎之功效,用于治疗湿浊中阻、脘痞不饥、脾胃虚寒、呕吐泄泻、妊娠恶阻、胎动不安;
石斛,性味:甘、微寒, 具有生津益胃、滋阴清热、润肺益肾、明目强腰之功效,用于治疗热病伤津、口干烦渴、胃阴不足、胃痛干呕、肺燥干咳、虚热不退、阴伤目暗、腰膝软弱;
岗梅根,性味:味苦、甘、性寒,具有清热解毒、生津止渴之功效,用于治疗感冒、高热烦渴、扁桃体炎、咽喉炎、气管炎、百日咳、腹泻、痢疾、传染性肝炎、野蕈、砒霜中毒,为凉茶产主要原料;叶外用于跌打损伤、痈疖肿毒。
本发明药物是基于中医治疗痛风的原则,从依据痛风的病理机制及药理作用认为:就痛风,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述痛风的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个很好的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种可有效治疗痛风的丸剂药物,其特征在于,所述药物的各个组分及质量份比如下所示:
威灵仙95g、海金沙120g、厚朴95g、羌活95g、五味子52g、甘草100g、白头翁120g、川朴95g、金银花230g、川贝母95g、鸡内金95g、砂仁52g、石斛120g、岗梅根260g,辅料:淀粉适量。
实施例2:
一种可有效治疗痛风的丸剂药物,其特征在于,所述药物的各个组分及质量份比如下所示:
威灵仙105g、海金沙140g、厚朴105g、羌活105g、五味子60g、甘草115g、白头翁140g、川朴105g、金银花260g、川贝母105g、鸡内金105g、砂仁60g、石斛140g、岗梅根310g,辅料:淀粉适量。
实施例3:
一种可有效治疗痛风的丸剂药物,其特征在于,所述药物的各个组分及质量份比如下所示:
威灵仙120g、海金沙160g、厚朴120g、羌活120g、五味子70g、甘草130g、白头翁160g、川朴120g、金银花300g、川贝母120g、鸡内金120g、砂仁70g、石斛160g、岗梅根350g,辅料:淀粉适量。
典型病例:
经临床诊断治疗痛风患者共1250例,年龄为66岁以上的801例,只有449例为66岁以下。1250例患者中血尿酸降至正常范围的有890例,有效的260例,无效的100例。总有效率达92%。
Claims (3)
1.一种可有效治疗痛风的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
威灵仙60~120g、海金沙60~160g、厚朴30~120g、羌活30~120g、五味子20~70g、甘草30~130g、白头翁100~160g、川朴30~120g、金银花150~300g、川贝母30~120g、鸡内金30~120g、砂仁30~70g、石斛60~160g、岗梅根150~350g,辅料:淀粉适量。
2.根据权利要求1所述的可有效治疗痛风的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
威灵仙70~105g、海金沙70~140g、厚朴38~105g、羌活38~105g、五味子23~60g、甘草38~115g、白头翁115~140g、川朴38~105g、金银花180~260g、川贝母38~105g、鸡内金38~105g、砂仁38~60g、石斛70~140g、岗梅根180~310g,辅料:淀粉适量。
3.根据权利要求1至2所述的可有效治疗痛风的丸剂药物,其特征在于,所述药物的各个组分及其质量份比如下所示:
威灵仙95g、海金沙120g、厚朴95g、羌活95g、五味子52g、甘草100g、白头翁120g、川朴95g、金银花230g、川贝母95g、鸡内金95g、砂仁52g、石斛120g、岗梅根260g,辅料:淀粉适量。
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