CN106822837A - 一种可有效治疗慢性支气管炎和支气管哮喘的中药组合物 - Google Patents
一种可有效治疗慢性支气管炎和支气管哮喘的中药组合物 Download PDFInfo
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- CN106822837A CN106822837A CN201710087738.XA CN201710087738A CN106822837A CN 106822837 A CN106822837 A CN 106822837A CN 201710087738 A CN201710087738 A CN 201710087738A CN 106822837 A CN106822837 A CN 106822837A
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- Medicines Containing Plant Substances (AREA)
Abstract
本发明属于中药制剂领域,目的是根据中医治疗慢性支气管炎和支气管哮喘的认识机理而提供的一种可有效治疗慢性支气管炎和支气管哮喘的中药组合物,所述中药组合物的各个组分及其质量份比如下:冬虫夏草36~90g、党参170~260g、白术(麸炒)36~140g、地龙60~90g、茯苓115~140g、麦冬115~230g、补骨脂(盐炒)70~90g、五味子(醋制)36~130g、胡桃肉115~320g、当归90~140g、法半夏36~90g、瓜蒌皮170~220g、苦杏仁60~90g、麻黄36~105g、黄连36~50g、大枣70~140g、紫苏子36~90g、紫菀60~90g、射干36~90g、百合180~480g、石膏(煅)170~520g、厚朴36~105g、前胡36~105g、侧柏叶70~105g、陈皮36~140g等;本发明提供的药物是一个标本兼治的中药组方。
Description
技术领域
本发明属于中药制剂领域,具体涉及一种可有效治疗慢性支气管炎和支气管哮喘的中药组合物,特别是供慢性支气管炎和支气管哮喘患者使用的中药组合物的领域。
背景技术
慢性支气管炎是气管、支气管黏膜及周围组织的慢性非特异性炎症。临床以咳嗽、咳痰为主要症状,每年发病持续3个月,连续2年或2年以上。需要进一步排除具有咳嗽、咳痰、喘息症状的其他疾病(如肺结核、尘肺、肺脓肿、心脏病、心功能不全、支气管扩张、支气管哮喘、慢性鼻咽炎、食管反流综合征等疾患)。
支气管哮喘是由多种细胞和细胞组分参与的气道慢性炎症性疾病,这种慢性炎症与气道高反应性相关,通常出现广泛而多变的可逆性气流受限,导致反复发作的喘息、气促、胸闷和(或)咳嗽等症状,多在夜间和(或)清晨发作、加剧,多数患者可自行缓解或经治疗缓解。
那么,就如何找到一种可有效治疗慢性支气管炎和支气管哮喘的中药组合物,是本领域技术人员亟待要解决的问题。
发明内容
随着我国中医中药学的不断发展,在治疗慢性支气管炎和支气管哮喘上,人们逐渐意识到了中医治疗慢性支气管炎和支气管哮喘的优点,且在治疗过程中疗效好、见效快、毒副作用小等优势,针对现有西医治疗慢性支气管炎和支气管哮喘的现状,本发明的目的是在于提供一种可有效治疗慢性支气管炎和支气管哮喘的中药组合物,以解决慢性支气管炎和支气管哮喘患者早日恢复健康的问题。该药物是以常见的中药为原料,通过选择合理的药物及质量份比,可有效治疗上述慢性支气管炎和支气管哮喘。
为达到上述发明的目的,本发明所采用的技术方案为:提供一种可有效治疗慢性支气管炎和支气管哮喘的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
冬虫夏草30~100g、党参150~300g、白术(麸炒)30~160g、地龙50~100g、茯苓100~160g、麦冬100~260g、补骨脂(盐炒)60~100g、五味子(醋制)30~150g、胡桃肉100~360g、当归80~160g、法半夏30~100g、瓜蒌皮150~250g、苦杏仁50~100g、麻黄30~120g、黄连30~60g、大枣60~160g、紫苏子30~100g、紫菀50~100g、射干30~100g、百合150~550g、石膏(煅)150~600g、厚朴30~120g、前胡30~120g、侧柏叶60~120g、陈皮30~160g、沉香25~60g、生姜30~120g、枇杷叶90~160g、橘红30~120g、川贝母30~120g、熟地黄120~380g、玄参100~180g、胆南星30~70g、 桔梗50~100g、桑白皮100~160g、知母60~150g、款冬花50~120g、连翘150~300g、金银花150~350g、荆芥30~120g、炙甘草20~100g。
一种可有效治疗慢性支气管炎和支气管哮喘的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
冬虫夏草36~90g、党参170~260g、白术(麸炒)36~140g、地龙60~90g、茯苓115~140g、麦冬115~230g、补骨脂(盐炒)70~90g、五味子(醋制)36~130g、胡桃肉115~320g、当归90~140g、法半夏36~90g、瓜蒌皮170~220g、苦杏仁60~90g、麻黄36~105g、黄连36~50g、大枣70~140g、紫苏子36~90g、紫菀60~90g、射干36~90g、百合180~480g、石膏(煅)170~520g、厚朴36~105g、前胡36~105g、侧柏叶70~105g、陈皮36~140g、沉香30~50g、生姜36~105g、枇杷叶100~140g、橘红36~105g、川贝母36~105g、熟地黄140~330g、玄参115~160g、胆南星36~60g、 桔梗60~90g、桑白皮115~140g、知母70~130g、款冬花60~105g、连翘170~260g、金银花170~310g、荆芥36~105g、炙甘草30~90g。
一种可有效治疗慢性支气管炎和支气管哮喘的中药组合物,其特征在于,所述“最佳方案”的中药组合物的各个组分及其质量份比如下所示:
冬虫夏草80g、党参230g、白术(麸炒)120g、地龙80g、茯苓120g、麦冬200g、补骨脂(盐炒)80g、五味子(醋制)115g、胡桃肉280g、当归120g、法半夏80g、瓜蒌皮200g、苦杏仁80g、麻黄95g、黄连42g、大枣120g、紫苏子80g、紫菀80g、射干80g、百合420g、石膏(煅)460g、厚朴95g、前胡95g、侧柏叶95g、陈皮120g、沉香42g、生姜95g、枇杷叶120g、橘红95g、川贝母95g、熟地黄280g、玄参140g、胆南星50g、 桔梗80g、桑白皮120g、知母115g、款冬花95g、连翘230g、金银花280g、荆芥95g、炙甘草80g。
一种可有效治疗慢性支气管炎和支气管哮喘的中药组合物,其特征在于,所述方法包括如下步骤制备而成:
A、将上述原料中药拣去杂质、粉尘及干燥后,按照质量份比共研为极细末待用;
B、按照传统制备中药胶囊剂的方法,将研磨好的极细末药物过筛后,放入药器中混合均匀,然后制备成胶囊剂(其胶囊锁合后总长度为23.3mm,药粉容量0.4~0.5g/粒),分装密封即可。
一种可有效治疗慢性支气管炎和支气管哮喘的中药组合物,其特征在于,所述服用方法为:将制备好的胶囊剂药物以每日二次服用,早晚各服一次,给药量2g(4粒)/次,温开水送服。15天为一个疗程,服药2~6个疗程,临床症状完全消失,病告痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料,充分发挥各组分的药理功效:
冬虫夏草,性味:甘、平,具有补肺益肾、止血化痰之功效,用于治疗久咳虚喘、劳嗽咯血、阳痿遗精、腰膝酸痛;
党参,性味:味甘、性平,具有健脾补肺、益气生津之功效,用于治疗脾胃虚弱、食少便溏、四肢乏力、肺虚喘咳、气短自汗、气微两亏;
白术(麸炒),性味:苦甘、温,具有健脾益气、燥湿利水、止汗、安胎之功效,用于治疗脾虚食少、腹胀泄泻、痰饮眩悸、水肿、自汗、胎动不安;
地龙,性味:味咸、性寒,具有清势止痉、平肝熄风、通经活络、平喘利尿之功效,用于治疗热病发热狂燥、惊痫抽搐、肝阳头痛、中风偏瘫、风湿痹痛、肺热喘咳、小便不通;
茯苓,性味:甘、淡、平,具有利水药、渗湿利尿药之功效,用于治疗小便不利、水肿胀满、痰饮咳逆、呕吐、脾虚食少、泄泻、心悸不安、失眠健忘、遗精白浊;
麦冬,性味:甘、微苦、微寒,具有养阴生津、润肺清心之功效,用于治疗肺燥干咳、虚痨咳嗽、津伤口渴、心烦失眠、内热消渴、肠燥便秘、咽白喉等症;
补骨脂(盐炒),性味:辛、苦、温,具有温肾助阳、纳气、止泻之功效,用于治疗阳痿遗精、遗尿尿频、腰膝冷痛、肾虚作喘、五更泄泻,外用治白癜风、斑秃;
五味子(醋制),性味:味酸、甘、性温,具有敛肺止咳、生津敛汗之功效,用于治疗咳喘、体虚多汗、津伤口渴,亦能涩精止泻,醋制能增强酸涩收敛作用,故醋五味子涩精止泻作用更强,多用于遗精滑泄、久泻不止,亦可用于久咳肺气耗散者,酒制五味子能增强其温补作用,多用于心肾虚损、梦遗滑精、心悸失眠,蜜制五味子补益肺肾作用增强,用于久咳虚喘;
胡桃肉,性味:甘温,具有补肾固精、温肺定喘、润肠通便之功效,用于治疗肾虚腰酸足软、阳痿遗精、虚阳痿遗精、虚寒咳喘、肺虚久咳、肠燥便秘等症;
当归,性味:性温、味甘辛,具有补血和血、调经止痛、润燥滑肠之功效,用于治疗血虚、面色萎黄、眩晕心悸、血虚、或兼有瘀滞的月经不调、经闭、痛经、虚寒性腹痛、冠心病心绞痛、风湿痹痛、跌打损伤;
法半夏,性味:辛、温,具有燥湿化痰之功效,用于治疗痰多咳喘、痰饮眩悸、风痰眩晕、痰厥头痛;
瓜蒌皮,性味:性味、甘、寒,具有清化热痰,利气宽胸之功效,用于治疗痰热咳嗽、胸闷胁痛、咽痛、胸痛、吐血、衄血、消渴、便秘、痈疮肿毒;
苦杏仁,性味:性温、味苦,有小毒,具有降气止咳平喘、润肠通便之功效,用于治疗咳嗽气喘、胸满痰多、血虚津枯、肠燥便秘等症;
麻黄,性味:辛;微苦、性温,具有发汗解表、宣肺平喘、利水消肿之功效,用于治疗风寒表实证、恶寒发热、无汗、头痛身疼、;邪壅于肺、肺气不宣、咳嗽气喘、风水肿、小便不利、风湿痹痛、肌肤不仁以及风疹瘙痒、阴疽痰核;
黄连,性味:苦、寒,具有泻火、燥湿、解毒、杀虫之功效,用于治疗时行热毒、伤寒、热盛心烦、痞满呕逆、菌痢、热泻腹痛、肺结按、吐、衄、下血、消渴、疳积、蛔虫病、百日咳、咽喉肿痛、火眼、口疮、痈疽疮毒、湿疹、汤火烫伤;
大枣,性味:甘、温,果(大枣),具有补中益气、养血安神之功效,用于治疗脾虚食少、乏力便溏、妇人脏躁;树皮:具有消炎、止血、止泻,用于气管炎、肠炎、痢疾、崩漏,外用治外伤出血;根:行气、活血、调经,用于月经不调、红崩、白带;
紫苏子,性味:辛、温,具有降气消痰、平喘、润肠之功效,用于治疗痰壅气逆、咳嗽气喘、肠燥便秘;
紫菀,性味:辛、苦、温,具有润肺下气、消痰止咳之功效,用于治疗痰多喘咳、新久咳嗽、劳嗽咳血;
射干,性味:苦、寒,具有清热解毒、消痰、利咽之功效,用于治疗热毒痰火郁结、咽喉肿痛、痰涎壅盛、咳嗽气喘;
百合,性味:甘、微苦、微寒,具有养阴润肺、清心安神之功效,用于治疗阴虚久嗽、痰中带血、热病后期、余热未清或情志不遂所致的虚烦惊悸、失眠多梦、精神恍惚、痈肿、湿疮等症;
石膏(煅),性味:甘、辛、涩、寒,具有收湿、生肌、敛疮、止血之功效,用于外治溃疡不敛、湿疹瘙痒、水火烫伤、外伤出血等病症;
厚朴,性味:苦、辛、温,具有燥湿消痰、下气除满之功效,用于治疗湿滞伤中、脘痞吐泻、食积气滞、腹胀便秘、痰饮喘咳;
前胡,性味:苦、辛、微寒,具有散风清热,降气化痰之功效,用于治疗风热咳嗽痰多、痰热喘满、咯痰黄稠;
侧柏叶,性味:苦、涩、寒,具有凉血止血、生发乌发之功效,用于治疗吐血衄血、咯血、便血、崩漏下血、血热脱发、须发早白等病症;
陈皮,性味:味辛、苦、性温,具有理气和中,燥湿化痰,利水通便之功效,用于治疗脾胃不和、脘腹胀痛、不思饮食、呕吐哕逆、痰湿阻肺、咳嗽痰多、胸膈满闷、头目眩晕、水肿、小便不利、大便秘结、乳痈疥癣、中鱼蟹毒、酒毒等症;
沉香,性味:辛苦、温,具有降气温中、暖肾纳气之功效,用于治疗气逆喘息、呕吐呃逆、脘腹胀痛、腰膝虚冷、大肠虚秘、小便气淋、男子精冷;
生姜,性味:味辛、性温,具有散寒解表、降逆止呕、化痰止咳之功效,用于治疗风寒感冒、恶寒发热、头痛鼻塞、呕吐、痰饮喘咳、胀满、泄泻等症;
枇杷叶,性味:苦、辛、寒,无毒,具有清肺止咳、和胃降逆、止渴之功效,用于治疗肺热痰嗽、阴虚劳嗽、咳血、衄血、胃热呕哕等症;
橘红,性味:辛、苦、温,具有散寒、燥湿、利气、消痰之功效,用于治疗风寒咳嗽、喉痒痰多、食积伤酒、呕恶痞闷;
川贝母,性味:苦、甘,微寒,具有清热润肺、化痰止咳之功效,用于治疗肺热燥咳、干咳少痰、阴虚劳嗽、咯痰带血,治虚劳咳嗽、吐痰咯血、心胸郁街、肺痿、肺痈、喉痹、乳痈等症;
熟地黄,性味:甘、微温,具有滋阴补血、益精填髓之功效,用于治疗肝肾阴虚、腰膝酸软、骨蒸潮热、盗汗遗精、内热消渴、血虚萎黄、心悸怔忡、月经不调、崩漏下血、眩晕、耳鸣、须发早白;
玄参,性味:味甘、苦、咸、性微寒,具有清热凉血、滋阴降火、解毒散结之功效,用于治疗温热病热和营血、身热、烦渴、舌绛、发斑、骨蒸劳嗽、虚烦不寤、津伤便秘、目涩昏花、咽喉喉肿痛、瘰疬痰核、痈疽疮毒;
胆南星,性味:苦、微辛、凉,具有清热化痰、息风定惊之功效,用于治疗痰热咳嗽、咯痰黄稠、中风痰迷、癫狂惊痫;
桔梗,性味:性平、味苦、辛,有小毒,具有祛痰、利咽、宣肺、排脓、利五脏、补气血、补五劳、养气之功效,用于主治咽喉肿痛、肺痈吐脓、咳嗽痰多、痢疾腹痛、胞满胁痛、口舌生疮、赤目肿痛、小便癃闭;
桑白皮,性味:味甘、辛、性寒,具有泻肺平喘、利水消肿之功效,用于治疗肺热喘咳痰、水饮停肺、胀满喘急、水肿、脚气、小便不利;
知母,性味:苦、甘、寒,具有清热泻火、生津润燥之功效,用于治疗外感热病、高热烦渴、肺热燥咳、骨蒸潮热、内热消渴、肠燥便秘;
款冬花,性味:辛、微苦、温,具有润肺下气,止咳化痰之功效,用于治疗新久咳嗽、喘咳痰多、劳嗽咳血;
连翘,性味:苦、凉,具有清热、解毒、散结、消肿之功效,用于治疗温热、丹毒、斑疹、痈疡肿毒、瘰疬、小便淋闭;
金银花,性味:甘、寒,具有清热解毒之功效,用于治疗温病发热、热毒血痢、痈肿疔疮、喉痹及多种感染性疾病;
荆芥,性味:味辛、微苦、性微湿,具有祛风、解表、透疹、止血之功效,用于治疗感冒发热、头痛、目痒、咳嗽、咽喉肿痛、麻疹、痈肿、疮疥、衄血、吐血、便血、崩漏、产后血晕;
炙甘草,性味:甘、平,具有补脾和胃、益气复脉之功效,用于治疗脾胃虚弱、倦怠乏力、心动悸、脉结代。
本发明药物是基于中医治疗慢性支气管炎和支气管哮喘的原则,从依据慢性支气管炎和支气管哮喘的病理机制及药理作用认为:就慢性支气管炎和支气管哮喘,本发明所提供的药物中的各原料中药药效共奏,对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述慢性支气管炎和支气管哮喘的治疗而提出的一种中药配方,采用该配方制备的药物药效好,见效快,是一个标本兼治的中药组方,特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述:
实施例1:
一种可有效治疗慢性支气管炎和支气管哮喘的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
冬虫夏草80g、党参230g、白术(麸炒)120g、地龙80g、茯苓120g、麦冬200g、补骨脂(盐炒)80g、五味子(醋制)115g、胡桃肉280g、当归120g、法半夏80g、瓜蒌皮200g、苦杏仁80g、麻黄95g、黄连42g、大枣120g、紫苏子80g、紫菀80g、射干80g、百合420g、石膏(煅)460g、厚朴95g、前胡95g、侧柏叶95g、陈皮120g、沉香42g、生姜95g、枇杷叶120g、橘红95g、川贝母95g、熟地黄280g、玄参140g、胆南星50g、 桔梗80g、桑白皮120g、知母115g、款冬花95g、连翘230g、金银花280g、荆芥95g、炙甘草80g。
实施例2:
一种可有效治疗慢性支气管炎和支气管哮喘的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
冬虫夏草90g、党参260g、白术(麸炒)140g、地龙90g、茯苓140g、麦冬230g、补骨脂(盐炒)90g、五味子(醋制)130g、胡桃肉320g、当归140g、法半夏90g、瓜蒌皮220g、苦杏仁90g、麻黄105g、黄连50g、大枣140g、紫苏子90g、紫菀90g、射干90g、百合480g、石膏(煅)520g、厚朴105g、前胡105g、侧柏叶105g、陈皮140g、沉香50g、生姜105g、枇杷叶140g、橘红105g、川贝母105g、熟地黄330g、玄参160g、胆南星60g、 桔梗90g、桑白皮140g、知母130g、款冬花105g、连翘260g、金银花310g、荆芥105g、炙甘草90g。
实施例3:
一种可有效治疗慢性支气管炎和支气管哮喘的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
冬虫夏草100g、党参300g、白术(麸炒)160g、地龙100g、茯苓160g、麦冬260g、补骨脂(盐炒)100g、五味子(醋制)150g、胡桃肉360g、当归160g、法半夏100g、瓜蒌皮250g、苦杏仁100g、麻黄120g、黄连60g、大枣160g、紫苏子100g、紫菀100g、射干100g、百合550g、石膏(煅)600g、厚朴120g、前胡120g、侧柏叶120g、陈皮160g、沉香60g、生姜120g、枇杷叶160g、橘红120g、川贝母120g、熟地黄380g、玄参180g、胆南星70g、 桔梗100g、桑白皮160g、知母150g、款冬花120g、连翘300g、金银花350g、荆芥120g、炙甘草100g。
典型病例
经临床诊断治疗慢性支气管炎和支气管哮喘患者共2040例,年龄为39岁以上的1030例,只有1010例为39岁以下。2040例患者中痊愈的1830例,有效的210例,总有效率达100%。
Claims (3)
1.一种可有效治疗慢性支气管炎和支气管哮喘的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
冬虫夏草30~100g、党参150~300g、白术(麸炒)30~160g、地龙50~100g、茯苓100~160g、麦冬100~260g、补骨脂(盐炒)60~100g、五味子(醋制)30~150g、胡桃肉100~360g、当归80~160g、法半夏30~100g、瓜蒌皮150~250g、苦杏仁50~100g、麻黄30~120g、黄连30~60g、大枣60~160g、紫苏子30~100g、紫菀50~100g、射干30~100g、百合150~550g、石膏(煅)150~600g、厚朴30~120g、前胡30~120g、侧柏叶60~120g、陈皮30~160g、沉香25~60g、生姜30~120g、枇杷叶90~160g、橘红30~120g、川贝母30~120g、熟地黄120~380g、玄参100~180g、胆南星30~70g、 桔梗50~100g、桑白皮100~160g、知母60~150g、款冬花50~120g、连翘150~300g、金银花150~350g、荆芥30~120g、炙甘草20~100g。
2.根据权利要求1所述的可有效治疗慢性支气管炎和支气管哮喘的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
冬虫夏草36~90g、党参170~260g、白术(麸炒)36~140g、地龙60~90g、茯苓115~140g、麦冬115~230g、补骨脂(盐炒)70~90g、五味子(醋制)36~130g、胡桃肉115~320g、当归90~140g、法半夏36~90g、瓜蒌皮170~220g、苦杏仁60~90g、麻黄36~105g、黄连36~50g、大枣70~140g、紫苏子36~90g、紫菀60~90g、射干36~90g、百合180~480g、石膏(煅)170~520g、厚朴36~105g、前胡36~105g、侧柏叶70~105g、陈皮36~140g、沉香30~50g、生姜36~105g、枇杷叶100~140g、橘红36~105g、川贝母36~105g、熟地黄140~330g、玄参115~160g、胆南星36~60g、 桔梗60~90g、桑白皮115~140g、知母70~130g、款冬花60~105g、连翘170~260g、金银花170~310g、荆芥36~105g、炙甘草30~90g。
3.根据权利要求1至2所述的可有效治疗慢性支气管炎和支气管哮喘的中药组合物,其特征在于,所述中药组合物的各个组分及其质量份比如下所示:
冬虫夏草80g、党参230g、白术(麸炒)120g、地龙80g、茯苓120g、麦冬200g、补骨脂(盐炒)80g、五味子(醋制)115g、胡桃肉280g、当归120g、法半夏80g、瓜蒌皮200g、苦杏仁80g、麻黄95g、黄连42g、大枣120g、紫苏子80g、紫菀80g、射干80g、百合420g、石膏(煅)460g、厚朴95g、前胡95g、侧柏叶95g、陈皮120g、沉香42g、生姜95g、枇杷叶120g、橘红95g、川贝母95g、熟地黄280g、玄参140g、胆南星50g、 桔梗80g、桑白皮120g、知母115g、款冬花95g、连翘230g、金银花280g、荆芥95g、炙甘草80g。
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CN110251629A (zh) * | 2019-08-08 | 2019-09-20 | 胡锡基 | 一种治疗哮喘的中药组合及其应用 |
WO2020024133A1 (zh) * | 2018-08-01 | 2020-02-06 | 陈霞 | 防治慢性支气管炎的面料 |
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CN109512927A (zh) * | 2018-12-14 | 2019-03-26 | 湖北荆江源制药股份有限公司 | 一种治疗支气管炎的中药丸 |
CN110251629A (zh) * | 2019-08-08 | 2019-09-20 | 胡锡基 | 一种治疗哮喘的中药组合及其应用 |
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