CN107796808A - A kind of portable detector - Google Patents
A kind of portable detector Download PDFInfo
- Publication number
- CN107796808A CN107796808A CN201710952324.9A CN201710952324A CN107796808A CN 107796808 A CN107796808 A CN 107796808A CN 201710952324 A CN201710952324 A CN 201710952324A CN 107796808 A CN107796808 A CN 107796808A
- Authority
- CN
- China
- Prior art keywords
- suction nozzle
- sample
- test paper
- liquid
- portable detector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0275—Interchangeable or disposable dispensing tips
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N2021/7756—Sensor type
- G01N2021/7759—Dipstick; Test strip
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N2021/7769—Measurement method of reaction-produced change in sensor
Abstract
The present invention relates to detection technique field.A kind of portable detector, including a liquid-transfering device, a suction nozzle；Liquid-transfering device is provided with the suction nozzle installation portion for being used for installing suction nozzle, and suction nozzle installation portion is detachably connected with suction nozzle；There is a cavity for being used to accommodate sample in suction nozzle；The both ends of suction nozzle are equipped with opening, and one end open is the liquid sucting port for importing sample, and another end opening is the installing port for connecting suction nozzle installation portion, and liquid sucting port turns on installing port with cavity；An inspection body is fixed with cavity, when sample submerges, can react one kind the inspection body for causing and examining body or sample chromatogram to change.Sample can be instilled into the step for examining test paper again after eliminating operator's sampling directly with examining body to react into the sample inside suction nozzle.Suction nozzle of the present invention is disposable, can reduce the probability of sample cross contamination.
Description
Technical field
The present invention relates to detection technique field, and in particular to a kind of optical information for being capable of analytical control body or sample solution
The detection means of situation of change.
Background technology
In fields such as medical diagnosis, food inspection, environment measurings, real-time field quick detection has important application valency
Value.
The markup reagent that determinand can be indicated is loaded into filter paper by test paper detection method using filter paper as medium.Test paper detects
Method be widely used in biological metabolism molecule (predetermined substance in such as mankind's urine, blood), immune molecule, remains of pesticide (such as cereal,
Fruit, processed food Pesticide Residues), the detection of the material such as environmental contaminants (such as chlorine residue, phenol, cyanide).
Conventional urinalysis test paper light weight, fragility, make troubles to transport, storing.Sample is lighted on test paper
Position it is improper will cause examine reaction can not be normally carried out so that measurement result is inaccurate.In addition, this urinalysis examination
Paper is often exposed in external environment, and its checkout procedure is also in this way, this will further decrease the degree of accuracy of assay.To sum up institute
State, this test paper detecting method is limited.
When being tested using urinalysis test paper, it need to ensure that sample uniformly, synchronously penetrates into the test section of test paper, enter
And ensure to carry out while reaction.And under the external environment detected at the scene, generally exist sample can not equably land in examination
The situation of paper, test section is caused completely can not equably to obtain the infiltration of sample.
Small-sized uroscopy instrument is common in domestic consumer, can automatically analyze urinalysis test paper.Multiple inspection items will be contained
The test strips immersion urine sample to be measured of mesh (i.e. multiple Examination regions), take out, drain unnecessary urine.Then, test strips are put into urine
Examine in instrument, the inspection of the Multiple components in urine sample, such as protein, leucocyte, acetoacetate, pH projects can be realized.
The limitation of examined scheme, this small-sized uroscopy instrument are only capable of realizing the semi-automation of detecting step.
Full automatic urine analyzer is common in various big hospital, utilizes automatic drip sample method and array analysis test paper, it is only necessary to grasp
Author places the test tube and test paper for filling sample, and a key can complete the detection of Multiple components in sample, moreover it is possible to realizes that batch is examined
Test.But sample remains significant period of time in the container such as sampling cup or test tube, caused wherein before being detected
Volatile matter be lost in.Meanwhile analytical instrument will also be polluted by volatile matter in sample.It is in addition, big in sample volatile matter
In the environment for measuring aggregation, the physically and mentally healthy of operator also will be by a certain degree of threat.Full automatic urine analyzer is also present
It is expensive, it is higher to operator's professional experiences level requirement the shortcomings that.
In addition, although above-mentioned fully-automatic analyzer employs disposable analysis test paper, loading analysis test paper
Paper box and grain-clamping table still have the possibility for being infiltrated, polluting by sample, it is long-term use of, can have the hidden danger of cross pollution.
To avoid cross pollution, this full automatic urine analyzer generally provides sampling needle cleaning function for oneself, it is ensured that after adopt
The sample of collection is not disturbed by the sample that the last time gathers.But this cleaning step, it can often be remained in sampling needle a small amount of clear
Washing lotion, the sample gathered after causing are diluted, so as to influence the accuracy of testing result.
There presently does not exist a kind of portable equipment that can detect residues of pesticides, i.e. only in the laboratory of specialty
The interior detection that could realize pesticide residue.When test in laboratory pesticide residue, it is desirable to which sample no cross contamination is dripped
On test paper.However, the step generally occur in the environment of opposing open, this by have influence on analysis result the degree of accuracy and can
Repeatability.
To realize the function of many kinds of substance in synchronous detection sample, a test paper often includes multiple Examination regions, can distinguished
Reacted with a variety of determinands.This may cause to interfere between adjacent test area, cause result inaccurate.
The content of the invention
It is an object of the present invention to provide a kind of portable detector, solves at least one technical problem above.
Technical problem solved by the invention can be realized using following technical scheme：
A kind of portable detector, it is characterised in that including a liquid-transfering device, a suction nozzle；
There is a cavity for being used to accommodate sample in the suction nozzle；
It is fixed with an inspection body in the cavity, inspection body or sample when examining body to mix with sample to react
Optical information changes；
The liquid-transfering device is provided with the suction nozzle installation portion for being used for installing the suction nozzle, the suction nozzle installation portion and the suction
Mouth is detachably connected；
The both ends of the suction nozzle are equipped with opening, and an opening is the liquid sucting port for importing sample, and another is open
For the installing port for connecting suction nozzle installation portion, the liquid sucting port turns on the installing port with the cavity；
By the liquid-transfering device, sample collection to suction nozzle internal cavities or is discharged from.
It can be eliminated into the sample inside suction nozzle directly with examining body to react after operator samples again by sample drop
Enter the step for examining test paper.Meanwhile the reaction of testing sample and inspection body is sealed in suction nozzle, therefore thing in testing sample
The volatilization of matter, the oxidation in body surface face is examined to be limited, so as to improve the stability of testing result, the safety of operating environment
Property.Suction nozzle of the present invention is disposable, and the probability of sample cross contamination will reduce.Further, since sample
Volatilization is suppressed, therefore those have the sample of special odor, such as urine, and what operator was brought unhappy can be subtracted
Gently.
Using liquid-transfering device by inside sample collection to suction nozzle, occurred using the inspection body inside suction nozzle and sample solution special
Opposite sex reaction, the idiosyncrasy can make the optical information of inspection body or sample change.According to optical information change to reaction
Situation is analyzed, and so as to realize the qualitative and quantitative analysis of sample, reaches medical diagnosis, food inspection, the mesh of environment measuring
's.It is of the invention compared with existing small-sized test paper detection, operation is more easy, more efficient；With large-scale test paper detection device
Compare, the real-time detection at scene can be realized.
For examining the structure design of body can be as follows：
As a kind of scheme, the inspection body is a test paper containing reaction reagent；
The reaction reagent is the reaction reagent for metachromasia to occur with sample.
Body is examined to include but is not limited to pH test paper, urinalysis test paper, enzyme linked immunoassay test paper, ambient water or gas point
Analysis test paper, agricultural chemicals test paper, quantitatively survey chlorine test paper, surfactant residual test paper.
The inspection body can be plane, and the central axis of plane and suction nozzle where the inspection body forms a non-90 degree
Angle.Preferably, one 15 °~35 ° of angle is formed.It is easy to observe.
The inside that body inclination will be examined to be fixed on suction nozzle, rational viewing angle is provided for human eye, is easy to range estimation reaction knot
Fruit, while also allow to carry out optical detection using optical sensor.
Alternatively, the inspection body is the spheroid for including reaction reagent；
The reaction reagent is the reaction reagent for metachromasia to occur with sample.
Spherical inspection physical efficiency fully contacts with sample in suction nozzle, so uniformly, fully absorb sample, promote reaction
Occur.
The inspection body is provided with least two detection zones；
The inspection body contains different reaction reagents in different detection zones；
From different materials metachromasia can occur for the different reaction reagent.
So as to be detected to many kinds of substance.
" discoloration " of the present invention refers to " optical information changes ", and the color that can be observed with the naked eye (can
See spectrum) change and can use the colorimetric determination of range estimation, alternatively, it is impossible to the optics (non-visible light to detect by an unaided eye
Spectrum) change, it can be detected using AAS (i.e. optical detection).According to the difference of detection method, liquid-transfering device
Construction it is also different, structure, the material feature of suction nozzle are also different.
The liquid-transfering device includes a syringe for being used to control sample to suck or discharge the suction nozzle, the syringe
A hollow chamber is inside provided with, a moveable piston is provided with the hollow chamber, the movement of the piston is used for for sample
Suction or discharge drainage；
The side of the piston is fixed with a drive shaft, and the drive shaft can drive piston to be slided in hollow chamber；
Side of the syringe away from the drive shaft is provided with the communication passage turned on the cavity of suction nozzle；
The communication passage turns on the chamber away from the drive shaft side in syringe；
The liquid-transfering device also includes a housing, and the syringe is fixed in the housing, and is opened up on the housing
There is the opening with the communication passage mutual conduction, the housing is stretched out in side of the drive shaft away from the communication passage；
In on the housing, the opening is located at the suction nozzle installation portion, the suction nozzle installation for the suction nozzle installation position
Portion can be with the suction nozzle dismantling connection.
There is drive shaft rebounding mechanism in the housing, when drive shaft is not by the power from hull outside, rebounding mechanism energy
Drive shaft is recovered to initial position automatically.
After installing suction nozzle, chamber of the syringe away from the drive shaft side can turn on suction nozzle inner space, slides and lives
Testing sample is drawn into suction nozzle by plug, the inspection body into the sample submergence suction nozzle inside suction nozzle, anti-with examining body to occur
Should, cause to examine the optical information of body or sample solution to change, so as to reach detect the determinand in sample
Purpose.
A light source, an optical sensor are further fixed on the suction nozzle installation portion；
The light emission direction of the light source is towards the cavity of the suction nozzle, and the sensing direction of the optical sensor is also towards institute
State the cavity of suction nozzle.
The light source is used for providing illumination or excitation spectrum, optical sensor be used for detecting the reflected light of carrying out self-checking body or
The transmitted light of sample solution.
Two light-transmitting openings are further opened with the housing, two light-transmitting openings are respectively used to the export of light source and light imports
Optical sensor；
The light source is fixed in the housing with the optical sensor.
The indication mechanism of the test result detected for showing optical sensor is fixed with the outer wall of the housing；
It is easy to examine the optical information of body or sample solution by indication mechanism, display.
There are measure loop and power supply in the housing；
The measure loop is used to collect information of the processing from optical sensor, and the power supply is used for for light source, detection
Device, measure loop, indication mechanism provide electric power.
The outer wall of housing is provided with operating mechanism, and the operating mechanism is used to control measure loop.
When the present invention uses optical detection, the liquid-transfering device of use includes light source, fluorescence detector, measure loop etc.
Structure；When detection method of the present invention using range estimation, the liquid-transfering device of use does not include said structure.
During detecting sample, the liquid sucting port of the suction nozzle is located at the lower end of suction nozzle, and installing port is located at the upper end of suction nozzle；
The liquid sucting port of suction nozzle is micromillimetre size, narrow upper width under internal diameter.
When ensureing containing liquids sample, sample does not drip because of Action of Gravity Field；It can ensure suction nozzle with upper width narrow at present
Volume.
Preferably, suction nozzle internal diameter is invariable after being gradually incremented by from bottom to up.Be easy to examine body in suction nozzle constant inner diameter not
Housed at change.
The suction nozzle can have any shape.
As a kind of reference scheme, the circular in cross-section or polygon of the suction nozzle.
When the cross section of suction nozzle is in polygon, that is, the upper end of the suction nozzle is in prism-shaped, the lower end of the suction nozzle
Portion is in internal diameter gradual incremental pyramid-shaped from bottom to up, the seamed edge number phase of the suction nozzle upper end and the suction nozzle bottom
Together.
It is that suction nozzle can be designed as follows for estimating：
As a kind of reference scheme, the suction nozzle is suction nozzle made of transparent material.It is easy to pass through outside detection suction nozzle
Estimate to assess the inspection body or sample solution color, depth state.
The cross section of the suction nozzle is in polygon.
When the cross section of suction nozzle is in polygon, that is, the upper end of the suction nozzle is in prism-shaped, the lower end of the suction nozzle
Portion is in internal diameter gradual incremental pyramid-shaped from bottom to up, the seamed edge number phase of the suction nozzle upper end and the suction nozzle bottom
Together.
The radius of curvature of suction nozzle outer wall is infinity under this structure, can eliminate suction nozzle bending outer wall to examining body
Dispersion interaction.The suction nozzle of this structure is easy to ocular estimate to obtain more accurate result.
Further, it is preferably, the wall thickness any place of suction nozzle is equal.It is easy to eliminate dispersion, is obtained when using ocular estimate
Result it is more accurate.
Suction nozzle for optical sensor detection can be designed as follows：
As a kind of reference scheme, the outer wall of suction nozzle can also have shade function.To prevent the interference of ambient light, ensure
Accuracy of detection when being detected using optical sensor.
The present invention can be used for the real-time, existing of the materials such as biological metabolism molecule, immune molecule, remains of pesticide, environmental contaminants
Field, automatic detection.Correspondingly, examine body include but is not limited to pH test paper, urinalysis test paper, enzyme linked immunoassay test paper,
Ambient water or gas analysis test paper, agricultural chemicals test paper, quantitatively survey chlorine test paper, surfactant residual test paper etc..Specifically：
The present invention can be used for pH to detect, wherein it is pH test paper to examine body.PH test paper is to refer to indicate sample by color
A kind of test paper of product pH value, such as the examination containing acid-base indicators such as bromothymol blues (Bromothymol Blue, BTB)
Paper, when sample is alkaline, test paper is in blue-green, is taken on a red color when acid.BTB indicator can be additionally used in the quantitative detection of determinand.
The present invention can be used for urinalysis, and inspection body is a kind of urinalysis test paper.Urinalysis test paper generally comprises more
Kind detection reagent, so as to be detected to many kinds of substance.The material that can be detected mainly includes but is not limited to leucocyte, nitrous
Hydrochlorate, UBG, protein, pH, blood, proportion, ascorbic acid, ketoboidies, bilirubin, glucose sugar.
The present invention can be used for enzyme linked immunosorbent detection.Suction nozzle of the present invention can successively gather sample, reaction reagent respectively.
Examine the antibody (antigen) that is fixed with and can be specifically bound with determined antigen (antibody) in body.Testing sample is gathered using suction nozzle,
Sample infiltration is set to examine body, then determined antigen (antibody) is with examining antibody (antigen) specific bond in body, reaction balance heel row
Go out testing sample.Then, the antibody (antigen) marked with suction nozzle collection enzyme, i.e. label, it is molten to discharge label after the completion of reaction
Liquid.Finally, zymolyte, i.e. developer are gathered with suction nozzle, makes the label on detection body that catalyzing hydrolysis or oxidation occur also
Original is reacted and specific color is presented.
The present invention can be used for the quantitative detection of the material such as phenols, dissolved oxygen, fluoride, cyanide in environment measuring：Reaction
When reagent includes 4-AA, body is examined to be used for the concentration for determining phenol；
When reaction reagent includes at least one of methylene blue, indigo reagent, body is examined to be used for during environment measuring
Detect the dissolved oxygen in sample；Methylene blue and the chemical reaction of indigo reagent and dissolved oxygen, coloring matter is generated, determines it
Absorbance, the quantitative detection to dissolved oxygen can be achieved；
When reaction reagent includes lanthanum nitrate, detection of the body for the fluoride in environment measuring is examined；Lanthanum nitrate and fluorine from
Son reaction generates blue ternary complexes, then fluoride can be measured by AAS；Reaction reagent includes alizarin
When sodium sulfonate and zirconates generation red complex, detection of the body for the fluoride in environment measuring is examined；Have in sample fluorine from
The period of the day from 11 p.m. to 1 a.m, zirconium ion in complex compound can be captured, generate colourless fluorination zirconium ion, discharge the sodium alizarine sulphonate of yellow, utilize mesh
Survey method, taken off according to solution by red to the colourity of yellow and standard colorimetric, so as to realize that the qualitative and quantitative of fluoride detects；
Reaction reagent includes pyridine-pyrazol quinoline ketone, examines detection of the body for the cyanide in environment measuring, passes through light splitting
Photometry carries out quantitative detection to cyanide.
The present invention can be used for the detection of organophosphor or carbamates in residues of pesticides, examine body to include indophenols and indophenols
Acetic acid esters.Organophosphor or carbamates are to the active inhibited of acetylcholine esterase in residues of pesticides, due to second
Phatidylcholine lipase participates in the indophenols and the balanced reaction of indophenols acetic acid esters that takes on a red color in blueness, using indophenols and indophenols acetic acid esters as
Indicator can determine the activity of acetylcholine esterase, so as to be detected to pesticide residue.
The present invention can be used for free chlorine to detect, and examine body to include N, during N- diethyl-Isosorbide-5-Nitrae-phenylenediamine (DPD).In sample
Free chlorine and DPD reaction after, absorbance of the free chlorine 515nm at can be surveyed, so as to reach the quantitative mesh for detecting sample chlorine residue
's.
The present invention can be used for surfactant to detect, and examine body to include methylenum careuleum.Utilize anion surfactant and Asia
First is blue to form blue-colored ionic associated matter, and blue-colored ionic associated matter determines its absorbance after chloroform extracts under 625nm light sources,
And then calculate the concentration of anion surfactant.
Brief description of the drawings
Fig. 1 is a kind of structural representation of the suction nozzle of the present invention；
Fig. 2 is another structural representation of the suction nozzle of the present invention；
Fig. 3 is another structural representation of the suction nozzle of the present invention；
Fig. 4 is another structural representation of the suction nozzle of the present invention；
Fig. 5 is a kind of structural representation of liquid-transfering device of the present invention；
Fig. 6 is a kind of structural representation that the present invention is provided with the liquid-transfering device detection sample state of suction nozzle；
Fig. 7 is that the present invention uses Fig. 6 structures not detect a kind of structural representation under sample state.
Embodiment
In order that the technical means, the inventive features, the objects and the advantages of the present invention are easy to understand, tie below
Conjunction, which is specifically illustrating, is expanded on further the present invention.
Reference picture 1, Fig. 2, Fig. 3, Fig. 4, Fig. 5, Fig. 6, Fig. 7, a kind of portable detector, including a liquid-transfering device 12, one
Suction nozzle 2；Liquid-transfering device 12 is provided with the suction nozzle installation portion for being used for installing suction nozzle 2, and suction nozzle installation portion is detachably connected with suction nozzle 2；
There is a cavity for being used to accommodate sample in suction nozzle 2；The both ends of suction nozzle 2 are equipped with opening, and one end open is for water conservancy diversion sample
Liquid sucting port 4, another end opening is the installing port 6 for connecting suction nozzle installation portion, and liquid sucting port 4 is led with installing port 6 with cavity
It is logical；An inspection body 8 is fixed with cavity, can be reacted when sample is with examining body 8 to mix, causes and examines body 8 or sample
Optical information produce change.By liquid-transfering device 12, sample collection to suction nozzle internal cavities or is discharged from.
It can be eliminated into the sample inside suction nozzle 2 directly with examining body 8 to react after operator samples again by sample
Instill the step for examining body 8.Meanwhile the reaction of testing sample and inspection body 8 is sealed in suction nozzle, therefore in testing sample
The volatilization of material, the oxidation on the surface of body 8 is examined to be limited, so as to improve the stability of testing result, the peace of operating environment
Quan Xing.Suction nozzle 2 of the present invention is disposable, and the probability of sample cross contamination will reduce.Further, since sample
Volatilization suppressed, therefore those have the sample of special odor, such as urine, and what operator was brought unhappy can also obtain
To mitigation.Using liquid-transfering device 12 by inside sample collection to suction nozzle 2, sent out using the inspection body 8 inside suction nozzle 2 and sample solution
Raw specific reaction, the idiosyncrasy can make the optical information of inspection body 8 or sample change.Utilize the change of optical information
Response situation is analyzed, so as to realize the qualitative and quantitative analysis of sample, reaches medical diagnosis, food inspection, environment measuring
Purpose.It is of the invention compared with existing small-sized test paper detection, operation is more easy, more efficient；Detected with large-scale test paper
Equipment is compared, and can realize the real-time detection at scene.
The application method of the suction nozzle 2 of built-in inspection body 8 is to be drained using liquid-transfering device 12, sample is entered in suction nozzle 2
Portion, and submerge and examine body 8.Determinand in sample is with examining the reaction reagent 10 contained by body 8 to react, reaction balance
Afterwards, sample is discharged into suction nozzle 2.The optical information situation of reaction reagent on body 8 is examined in detection, by the result and standard with reference to than
Compared with so as to reach the purpose of qualitative and quantitative analysis determinand., will after detection method of the present invention, in addition to reaction balance
Sample is retained in inside suction nozzle 2, detects the transmitted light situation of change of sample solution, by the result compared with standard reference, so as to
Reach the purpose of qualitative and quantitative analysis determinand.
It is a test paper containing reaction reagent 10 to examine body 8；Reaction reagent 10 is for metachromasia to occur with sample
Reaction reagent 10.Cleaning Principle involved by inspection body 8 and contained reaction reagent 10 includes：It is existing to be related to spectrum production
Reaction that is raw, disappearing or change, the reaction such as to be changed using color (color reaction) is detected to UBG, profit
Ferric ion is detected etc. with AAS (i.e. chromogenic reaction).Examine the optical information of body 8 can by detecting
Test substance is qualitatively identified, the light intensity by detecting feature light wave can quantitatively detect the concentration of determinand.
Body 8 is examined to include but is not limited to pH test paper, urinalysis test paper, enzyme linked immunoassay test paper, ambient water or gas
Analysis test paper, agricultural chemicals test paper, quantitatively survey chlorine test paper, surfactant residual test paper.
As a kind of scheme, body 8 is examined to be plane, and the plane where inspection body and the central axis of suction nozzle 2 form one
Non-90 degree angle.The inside that body will be examined to be inclined at suction nozzle 2, rational viewing angle is provided for human eye, is easy to range estimation to react
As a result, while also allow to carry out optical detection using sensor.
Alternatively, it is the spheroid for including reaction reagent 10 to examine body 8；Reaction reagent 10 is to be used to send out with sample
The reaction reagent 10 for the colour response that changes.Spherical detection physical efficiency fully contacts with sample in suction nozzle 2, and then uniformly, fully absorbs
Sample, promote the generation of reaction.As a kind of preferred scheme, body is examined to include a hollow baton round, the inwall of baton round is filled out
Filled with adsorption layer made of sponge, reaction reagent is impregnated with adsorption layer, baton round is baton round made of transparent material.Plastics
The side of ball offers the through hole flowed into for sample inside baton round.It is easy to sample via through holes to react with reaction reagent to be shown
Colour response.
Body is examined to be provided with least two detection zones；Body is examined to contain different reaction examinations in different detection zones
Agent；From different materials metachromasia can occur for different reaction reagents.So as to be detected to many kinds of substance.Preferably,
Central axial direction of the body along suction nozzle 2 is examined to be provided with least two detection zones for realizing sample different material measure；Inspection
Test body and contain different reaction reagents in different detection zones.So as to be detected to many kinds of substance.The bag of display one in Fig. 4
Include the specific embodiment of the suction nozzle of tri- different detection zones of 8a, 8b, 8c.
Liquid-transfering device 12 includes a syringe 18 for being used to control sample to suck or discharge, and is provided with syringe 18 in one
Plenum chamber, be provided with hollow chamber one can in the piston 20 of chamber indoor moving, the movement of piston 20 be used for for sample suction or
Discharge drainage；The side of piston 20 is fixed with the drive shaft 22 that a driving piston 20 slides in hollow chamber；Syringe 18 is remote
Side from drive shaft 22 is provided with the communication passage that turn on the cavity of suction nozzle 2, and communication passage and syringe are away from drive shaft 22
The chamber conducting of side.After installing suction nozzle 2, chamber of the syringe away from the side of drive shaft 22 can turn on the inner space of suction nozzle 2,
Testing sample is drawn into suction nozzle 2 by sliding plunger 20, into the interior detection body 8 of sample submergence suction nozzle 2 inside suction nozzle 2, with inspection
Test body 8 to react, cause to examine the optical information of body 8 or sample solution to change, so as to reach to be measured in sample
The purpose that thing is detected.
The one end of drive shaft away from piston, there is a pressing position 24.Drive shaft 22 has automatic rebound function (diagram is omited),
When operator presses to pressing position 24, drive shaft 22 promotes piston 20 to be slided to the end of communication passage 16, if now liquid-transfering device
12 are mounted with suction nozzle 2, and have liquid in suction nozzle 2, then liquid will be discharged in suction nozzle 2；When operator removes pressing position 24
Pressure, drive shaft 22 rebound to initial position automatically, if now liquid-transfering device 12 is mounted with suction nozzle 2, and at the liquid sucting port of suction nozzle 2
In liquid internal, then liquid will be attracted into suction nozzle 2.
Liquid-transfering device 12 includes a housing 14, and syringe 18 is fixed in housing 14, and is offered on housing 14 and UNICOM
The opening of passage mutual conduction, opening are located at suction nozzle installation portion；Housing 14 is stretched out in side of the drive shaft 22 away from communication passage.
A light source 26, an optical sensor 28 are further fixed on suction nozzle installation portion；The light emission direction of light source 26 is towards suction nozzle 2
Cavity, the sensing direction of optical sensor 28 is also towards the cavity of suction nozzle 2.Light source 26 is used for providing illumination or excitation spectrum,
Optical sensor is used for detecting the reflected light for carrying out self-checking body or the transmitted light of sample solution.The characteristics of light source 26, is, according to inspection
Cleaning Principle is different used by surveying body 8, and light source 26 has different spectral signatures, can be exciting light or lighting source, such as send out
Optical diode or laser diode.Cleaning Principle is different used by according to detection body 8, and optical sensor 28 has different spies
Sign, can be photodiode or the light sensor with optical filter.
The characteristic spectrum of light source 26, determined by the detection object of liquid-transfering device 12, be visible light wave range, ultraviolet or near-infrared
The spectrum of wave band.The Detection wavelength of optical sensor 28, by the characteristic spectrum and the light of inspection body 8 or sample solution of light source 26
Information is learned to determine.
Include a measure loop 30 in housing 14, measure loop 30 can be a signal processing module, and the measure loop connects
Connect optical sensor 28.Measure loop 30 can be collected, handle the detection signal from optical sensor 28, and the signal includes inspection
Test the optical information of body 8 or sample solution.
Two light-transmitting openings are further opened with housing 14, two light-transmitting openings are respectively used to the export of light source 26 and light imports
Optical sensor 28；Light source 26 is fixed in housing 14 with optical sensor 28.
The surface of housing 14 is provided with operation button 32.Power on or pass of the operation button 32 for control liquid-transfering device 12
Close, control the beginning of optical detection.
Indication mechanism 34 is fixed with the outer wall of housing 14.The feature of indication mechanism 34 be can show detection result,
Indicate operation link.
In addition, operation button 32 and indication mechanism 34 can also be integrated in a touch display screen.
Light source 26, optical sensor 28, measuring loop 30, operation button 32 and indication mechanism 34 form circuit loop.Move
Liquid device 12 also includes a power supply, and the power supply includes a battery or rechargeable battery.The power supply is used for for light source 26, optical sensor
28th, measuring loop 30 and indication mechanism 34 supply electric power.
Specifically, portable detector detection method of the present invention is that suction nozzle 2 is arranged on liquid-transfering device 12,
Calibrate measure loop 30.Sample collection is entered into suction nozzle, makes sample submergence detection body 8.After several seconds, sample is discharged.Utilize LED light source
26 provide illumination for detection body 8, are gathered using optical sensor 28 come the reflected light of Autonomous test body 8.Or after the several seconds, utilize
LED light source 26 provides light source for sample solution, and the transmitted light from sample solution is gathered using optical sensor 28.Using mould/
Signal from optical sensor 28 is converted to data signal, the optics letter that analysis optical sensor 28 gathers by number converter
Breath.Profit in this way, can qualitative, quantitatively detect the determinand in sample solution.
Or portable detector detection method of the present invention is that sample collection is entered into suction nozzle, make sample submergence inspection
Survey body 8.After several seconds, sample solution in suction nozzle and standard color comparison card are contrasted, sample is analyzed with examining body by the method for range estimation
Response situation.Profit in this way, can it is qualitative, semi-quantitatively analyze sample in determinand.
With reference to the suction nozzle and liquid-transfering device 12, the present invention proposes a kind of method for quantitatively detecting remains of pesticide.Utilize agriculture
Medicine residue can suppress the active principle of acetylcholine esterase, and using pH test paper as instruction, second is hydrolyzed with acetylcholine esterase
The process of phatidylcholine is Indicator Reaction system, indicates, assesses the activity of acetylcholine esterase by the pH of the reaction system, enter
One step quantitatively detects the concentration of pesticide residue.Specifically, it is test paper form to examine body 8, and the one side of test paper contains and can reacted
The indicator of pH value, the other one side of test paper contain acetylcholine and acetylcholine esterase powder.After suction nozzle collection sample, sample
Body 8 is examined in product submergence, is examined the acetylcholine on body 8 to be catalyzed through acetylcholine esterase and is produced hydrogen ion, causes to examine on body 8
The color of pH indicator changes.The optical information of body 8 is examined using the detection of optical sensor 28 of liquid-transfering device 12.This
Outside, 8 A/D converters can be used, then its saturated light intensity resolution is 255.If in calibration process, optical sensor detection
The bias light intensity of wave arrived is R (red)=60, G (green)=30, B (indigo plant)=40；After the completion of reaction, what optical sensor detected
Light wave intensity is R=60, G=30, B=150, and it is to generate blueness to show the color change for detecting body 8.Therefore, analysis is passed through
The color change situation of body 8 is detected, determinand can be analyzed and identified.
During detecting sample, liquid sucting port is located at the lower end of suction nozzle, and installing port is located at the upper end of suction nozzle；The imbibition of suction nozzle
Mouthful it is micromillimetre size, narrow upper width, circular in cross-section or polygon under internal diameter.Preferably, suction nozzle internal diameter is gradual from bottom to up
It is invariable after being incremented by.It is easy to examine body to house at the constant place of suction nozzle constant inner diameter.
Suction nozzle can have any shape.
As a kind of reference scheme, the circular in cross-section or polygon of suction nozzle.
When the cross section of suction nozzle is in polygon, that is, the upper end of suction nozzle is in prism-shaped, and the bottom of suction nozzle is in internal diameter
Gradually incremental pyramid-shaped, suction nozzle upper end are identical with the seamed edge number of suction nozzle bottom from bottom to up.
It is that suction nozzle can be designed as follows for estimating：
As a kind of reference scheme, suction nozzle is suction nozzle made of transparent material.It is easy to pass through range estimation outside detection suction nozzle
Body or sample solution color, depth state are examined to assess.
The cross section of suction nozzle is in polygon.
When the cross section of suction nozzle is in polygon, that is, the upper end of suction nozzle is in prism-shaped, and the bottom of suction nozzle is in internal diameter
Gradually incremental pyramid-shaped, suction nozzle upper end are identical with the seamed edge number of suction nozzle bottom from bottom to up.
The radius of curvature of suction nozzle outer wall is infinity under this structure, can eliminate suction nozzle bending outer wall to examining body
Dispersion interaction.The suction nozzle of this structure is easy to ocular estimate to obtain more accurate result.
Further, it is preferably, the wall thickness any place of suction nozzle is equal.It is easy to eliminate astigmatism, is obtained when using ocular estimate
Result it is more accurate.
It is that suction nozzle can be designed as follows for optical sensor monitoring：
As a kind of reference scheme, the outer wall of suction nozzle can also have shade function.To prevent the interference of ambient light, ensure
Accuracy of detection when being detected using optical sensor.
The used detection method of suction nozzle 2 and liquid-transfering device 12 of the present invention is as follows：
First, suction nozzle is arranged in detection means 12.Using syringe 18, certain volume is gathered by liquid sucting port 4
Testing sample.As shown in fig. 6, after the testing sample of the volume enters suction nozzle 2, body 8 is examined in submergence, is sent out between sample and inspection body
Raw reaction.
After reaction balance, sample S (Fig. 6) is discharged from liquid sucting port 4.Now, operator is activated by operation button 32 and surveyed
Step is measured, then light source 26 is opened, and body 8 is examined in irradiation, and the collection of optical sensor 28 carrys out the reflected light of self-checking body 8；Or reaction
After balance, operator activates measuring process by operation button 32, then light source 26 is opened, and excites sample solution S, optical sensor
28 transmitted lights of the collection from sample solution S.Measuring loop 30 collects the detection signal from optical sensor 28, to the signal
Analyzed and processed.Measuring loop 30 is provided with data storage function, can calculate, store and come self-checking body 8 or sample solution
Characteristic optical information.Therefore measuring loop 30 can provide data look-up functions.In addition, measuring loop 30 can pass through standard work
Composition line computation goes out the concentration of determinand, realizes quantitative detection.Data search, testing result are represented by indication mechanism 34.
Or after reaction balance, sample S (Fig. 6) is discharged from liquid sucting port 4.Now, operator will detect body and standard ratio
Color thing compares, and judges reaction result；Or after reaction balance, operator compares sample solution S with standard colorimetric thing, judges
Reaction result.Now, suction nozzle can allow for operator to pass through the method for range estimation to identify the reaction feelings of inspection body 8 and sample solution
Condition.For example, suction nozzle can be made up of transparent plastic material.It is one plane to examine body 8, is fixed in the chamber inside suction nozzle 2.
The plane at the place of body 8 is examined to form the angle of a non-90 degree with the axle center of suction nozzle 2, as shown in Figure 6.Inclined inspection body is human eye
Rational viewing angle is provided, is easy to estimate reaction result；Also liquid-transfering device 12 is allowed to be carried out using optical sensor 28 simultaneously
Optical detection.
Further, if the Cleaning Principle for examining body 8 to use only needs range estimation to reach inspection purpose, examined without optics
Survey, then the liquid-transfering device 12 used in the detection method does not include light source 26, sensor 28 or measure loop 30.
The present invention can be used for the real-time, existing of the materials such as biological metabolism molecule, immune molecule, remains of pesticide, environmental contaminants
Field, automatic detection.Correspondingly, examine body 8 include but is not limited to pH test paper, urinalysis test paper, enzyme linked immunoassay test paper,
Ambient water or gas analysis test paper, agricultural chemicals test paper, quantitatively survey chlorine test paper, surfactant residual test paper etc..Specifically：
The present invention can be used for pH to detect, wherein it is pH test paper to examine body 8.PH test paper is to refer to indicate sample by color
A kind of test paper of product pH value, such as the examination containing acid-base indicators such as bromothymol blues (Bromothymol Blue, BTB)
Paper, when sample is alkaline, test paper is in blue-green, is taken on a red color when acid.BTB indicator can be additionally used in the quantitative detection of determinand.
The present invention can be used for urinalysis, wherein it is a kind of urinalysis test paper to examine body 8.Urinalysis test paper generally wraps
Containing a variety of detection reagents, so as to be detected to many kinds of substance.The material that can be detected mainly include but is not limited to leucocyte,
Nitrite, UBG, protein, pH, blood, proportion, ascorbic acid, ketoboidies, bilirubin, glucose sugar.
The present invention can be used for enzyme linked immunosorbent detection.Suction nozzle 2 of the present invention can successively gather sample, reaction examination respectively
Agent.Examine the antibody (antigen) that fixation can be specifically bound with determined antigen (antibody) in body 8.Test sample is treated using suction nozzle collection
Product, sample infiltration is set to examine body, then determined antigen (antibody) is with examining antibody (antigen) specific bond in body, after reacting balance
Discharge testing sample.Then, the antibody (antigen) marked with suction nozzle collection enzyme, i.e. label, label is discharged after the completion of reaction
Solution.Finally, zymolyte, i.e. developer are gathered with suction nozzle, makes the label on detection body that catalyzing hydrolysis or oxidation occur
Reduction reaction and specific color is presented.
The present invention can be used for the quantitative detection of the material such as phenols, dissolved oxygen, fluoride, cyanide in environment measuring：
When reaction reagent 10 includes 4-AA, body 8 is examined to can be used for the concentration of measure phenol；
When reaction reagent 10 includes at least one of methylene blue, indigo reagent, body 8 is examined to can be used for environment measuring
The dissolved oxygen in sample is detected in journey；Methylene blue and the chemical reaction of indigo reagent and dissolved oxygen, coloring matter is generated, surveyed
Its fixed absorbance, realizes the quantitative detection to dissolved oxygen；
When reaction reagent 10 includes lanthanum nitrate, detection of the body 8 available for the fluoride in environment measuring is examined；Lanthanum nitrate with
Fluorine ion reaction generates blue ternary complexes, and fluoride is measured by AAS；
When reaction reagent 10 includes sodium alizarine sulphonate and zirconates generation red complex, body 8 is examined also to can be used for environment to examine
The detection of fluoride in survey；When having fluorine ion in sample, zirconium ion in complex compound can be captured, generate colourless zirconium fluoride from
Son, the sodium alizarine sulphonate of yellow is discharged, using ocular estimate, is taken off according to solution by red to the colourity of yellow and standard colorimetric,
So as to carry out the detection of fluoride with quantifying；
Reaction reagent 10 includes pyridine-pyrazol quinoline ketone, examines detection of the body 8 for the cyanide in environment measuring, passes through
AAS carries out quantitative detection to cyanide.
The present invention can be used for the detection of organophosphor or carbamates in residues of pesticides, and wherein reaction reagent 10 includes indigo
Phenol and indophenols acetic acid esters.Organophosphor or carbamates have to the activity of acetylcholine esterase in residues of pesticides suppresses to make
With because acetylcholine esterase participates in the balanced reaction of the indophenols and the indophenols acetic acid esters to take on a red color in blueness, with indophenols and indigo
Phenol acetic acid esters is the activity that indicator can determine acetylcholine esterase, so as to be detected to pesticide residue.
The present invention can be used for free chlorine to detect, and wherein reaction reagent 10 includes N, N- diethyl-Isosorbide-5-Nitrae-phenylenediamine (DPD).
Free chlorine in sample is with that after DPD reactions, can survey absorbance of the free chlorine at 515nm, so as to reach in quantitative detection sample
The purpose of chlorine residue.
The present invention can be used for surfactant to detect, and wherein reaction reagent 10 includes methylenum careuleum.Lived using anionic surface
Property agent and methylenum careuleum form blue-colored ionic associated matter, blue-colored ionic associated matter determines it after chloroform extracts under 625nm light sources
Absorbance, and then calculate the concentration of anion surfactant.
The general principle and principal character and advantages of the present invention of the present invention has been shown and described above.The technology of the industry
Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the simply explanation described in above-described embodiment and specification is originally
The principle of invention, without departing from the spirit and scope of the present invention, various changes and modifications of the present invention are possible, these changes
Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appended claims and its
Equivalent thereof.
Claims (10)
1. a kind of portable detector, it is characterised in that including a liquid-transfering device, a suction nozzle；
There is a cavity for being used to accommodate sample in the suction nozzle；
An inspection body is fixed with the cavity, the optics of body or sample is examined when examining body to be mixed with sample and reacting
Information changes；
The liquid-transfering device is provided with the suction nozzle installation portion for being used for installing the suction nozzle, and the suction nozzle installation portion can with the suction nozzle
Dismantling connection；
The both ends of the suction nozzle are equipped with opening, and one end open is the liquid sucting port for importing sample, and another end opening is use
In the installing port of connection suction nozzle installation portion, the liquid sucting port turns on the installing port with the cavity；
By the liquid-transfering device, sample collection to suction nozzle internal cavities or is discharged from.
A kind of 2. portable detector according to claim 1, it is characterised in that：The suction nozzle is made of transparent material
Suction nozzle.
A kind of 3. portable detector according to claim 1, it is characterised in that：The inspection body is one containing reaction examination
The test paper of agent；
The reaction reagent is the reaction reagent for metachromasia to occur with sample.
A kind of 4. portable detector according to claim 3, it is characterised in that：Body is examined to include pH test paper, urine point
Analyse test paper, enzyme linked immunoassay test paper, ambient water or gas analysis test paper, agricultural chemicals test paper, quantitatively survey chlorine test paper, surface work
Property agent residual at least one of test paper.
A kind of 5. portable detector according to claim 1, it is characterised in that：It is described to examine body to be plane, it is described
The central axis of plane and suction nozzle where inspection body forms a non-90 degree angle.
A kind of 6. portable detector according to claim 1, it is characterised in that：The inspection body is to include reaction reagent
Spheroid；
The reaction reagent is the reaction reagent for metachromasia to occur with sample.
A kind of 7. portable detector according to claim 1, it is characterised in that：The inspection body is provided with least two
Detection zone；
The inspection body contains different reaction reagents in different detection zones；
From different materials metachromasia can occur for the different reaction reagent.
A kind of 8. portable detector according to claim 1, it is characterised in that：The liquid-transfering device includes one and is used to control
Sample preparation product suck or discharged the syringe of the suction nozzle, are provided with a hollow chamber in the syringe, in the hollow chamber
Provided with a moveable piston, the movement of the piston is used for suction or discharge drainage for sample；
The side of the piston is fixed with a drive shaft, and the drive shaft can drive piston to be slided in hollow chamber；
Side of the syringe away from the drive shaft is provided with the communication passage turned on the cavity of suction nozzle；
The communication passage turns on the chamber away from the drive shaft side in syringe；
The liquid-transfering device also includes a housing, and the syringe is fixed in the housing, and offered on the housing with
The opening of the communication passage mutual conduction, the opening are located at the suction nozzle installation portion；
The housing is stretched out in side of the drive shaft away from the communication passage.
A kind of 9. portable detector according to claim 8, it is characterised in that：It is further fixed on the suction nozzle installation portion
One light source, an optical sensor；
The light emission direction of the light source is towards the cavity of the suction nozzle, and the sensing direction of the optical sensor is also towards the suction
The cavity of mouth；
Two light-transmitting openings are further opened with the housing, two light-transmitting openings are respectively used to export and the light introduction optical of light source
Sensor；
The light source is fixed in the housing with the optical sensor；
The indication mechanism of the test result detected for showing optical sensor is fixed with the outer wall of the housing.
A kind of 10. portable detector according to claim 1, it is characterised in that：During detecting sample, liquid sucting port
Positioned at the lower end of suction nozzle, installing port is located at the upper end of suction nozzle；
The liquid sucting port of the suction nozzle is micromillimetre size, narrow upper width under suction nozzle internal diameter；
The circular in cross-section or polygon of the suction nozzle.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710952324.9A CN107796808A (en) | 2017-10-13 | 2017-10-13 | A kind of portable detector |
| CN201810243455.4A CN108508006A (en) | 2017-10-13 | 2018-03-23 | A kind of portable detector |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710952324.9A CN107796808A (en) | 2017-10-13 | 2017-10-13 | A kind of portable detector |
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| CN107796808A true CN107796808A (en) | 2018-03-13 |
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| CN201710952324.9A Pending CN107796808A (en) | 2017-10-13 | 2017-10-13 | A kind of portable detector |
| CN201810243455.4A Pending CN108508006A (en) | 2017-10-13 | 2018-03-23 | A kind of portable detector |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108760731A (en) * | 2018-06-01 | 2018-11-06 | 南京新循环保科技有限公司 | Chemical composition rapid detection method |
| CN108872560A (en) * | 2018-08-14 | 2018-11-23 | 湖北伽诺美生物科技有限公司 | A kind of portable urine quantitative testing device |
| CN108956592A (en) * | 2018-06-01 | 2018-12-07 | 南京新循环保科技有限公司 | Chemical component detection device |
| CN110095456A (en) * | 2019-04-12 | 2019-08-06 | 中国农业科学院烟草研究所(中国烟草总公司青州烟草研究所) | A kind of tobacco virus detection display and application method |
| CN110389057A (en) * | 2018-04-23 | 2019-10-29 | 上海伯顿医疗设备有限公司 | Integrated multi-functional biological sample processor |
| CN111323413A (en) * | 2020-02-17 | 2020-06-23 | 中国农业大学 | Device for detecting pesticide by evaporating solution-nucleic acid test paper |
| CN111879768A (en) * | 2020-07-30 | 2020-11-03 | 上海化工研究院有限公司 | Multifunctional acid-base gradient rapid detection bottle with segmented color development function and application thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101078730A (en) * | 2006-05-22 | 2007-11-28 | 杜宏武 | Enzyme labeled chip method capable of in situ detecting multiple ordinary small molecule drugs |
| US20100167412A1 (en) * | 2008-12-31 | 2010-07-01 | Caibin Xiao | Sensor system for determining concentration of chemical and biological analytes |
| WO2011032228A1 (en) * | 2009-09-18 | 2011-03-24 | Minifab (Australia) Pty Ltd | Instrumented pipette |
| JP5267617B2 (en) * | 2011-06-23 | 2013-08-21 | ウシオ電機株式会社 | Analysis apparatus and analysis method |
| US9686540B2 (en) * | 2014-06-23 | 2017-06-20 | Xerox Corporation | Robust colorimetric processing method for paper based sensors |
| CN104964973A (en) * | 2015-07-08 | 2015-10-07 | 邓双胜 | Test paper reading and analyzing method and system based on mobile terminal camera |
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2017
- 2017-10-13 CN CN201710952324.9A patent/CN107796808A/en active Pending
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- 2018-03-23 CN CN201810243455.4A patent/CN108508006A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110389057A (en) * | 2018-04-23 | 2019-10-29 | 上海伯顿医疗设备有限公司 | Integrated multi-functional biological sample processor |
| CN108760731A (en) * | 2018-06-01 | 2018-11-06 | 南京新循环保科技有限公司 | Chemical composition rapid detection method |
| CN108956592A (en) * | 2018-06-01 | 2018-12-07 | 南京新循环保科技有限公司 | Chemical component detection device |
| CN108872560A (en) * | 2018-08-14 | 2018-11-23 | 湖北伽诺美生物科技有限公司 | A kind of portable urine quantitative testing device |
| CN110095456A (en) * | 2019-04-12 | 2019-08-06 | 中国农业科学院烟草研究所(中国烟草总公司青州烟草研究所) | A kind of tobacco virus detection display and application method |
| CN110095456B (en) * | 2019-04-12 | 2021-08-20 | 中国农业科学院烟草研究所(中国烟草总公司青州烟草研究所) | Tobacco virus detection and development device and use method |
| CN111323413A (en) * | 2020-02-17 | 2020-06-23 | 中国农业大学 | Device for detecting pesticide by evaporating solution-nucleic acid test paper |
| CN111879768A (en) * | 2020-07-30 | 2020-11-03 | 上海化工研究院有限公司 | Multifunctional acid-base gradient rapid detection bottle with segmented color development function and application thereof |
| CN111879768B (en) * | 2020-07-30 | 2022-03-18 | 上海化工研究院有限公司 | Multifunctional acid-base gradient rapid detection bottle with segmented color development function and application thereof |
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| CN108508006A (en) | 2018-09-07 |
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