CN107789719B - Inner core-free thrombolysis catheter - Google Patents
Inner core-free thrombolysis catheter Download PDFInfo
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- CN107789719B CN107789719B CN201711114153.9A CN201711114153A CN107789719B CN 107789719 B CN107789719 B CN 107789719B CN 201711114153 A CN201711114153 A CN 201711114153A CN 107789719 B CN107789719 B CN 107789719B
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- catheter
- thrombolytic
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- coreless
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- 230000002537 thrombolytic effect Effects 0.000 title claims abstract description 54
- 239000003146 anticoagulant agent Substances 0.000 claims abstract description 29
- 208000007536 Thrombosis Diseases 0.000 claims abstract description 28
- 230000010412 perfusion Effects 0.000 claims abstract description 20
- 239000003527 fibrinolytic agent Substances 0.000 claims abstract description 16
- 230000000149 penetrating effect Effects 0.000 claims abstract description 13
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims abstract description 6
- 229960002897 heparin Drugs 0.000 claims abstract description 6
- 229920000669 heparin Polymers 0.000 claims abstract description 6
- 238000012377 drug delivery Methods 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 4
- 238000001802 infusion Methods 0.000 claims description 3
- 241000405070 Percophidae Species 0.000 claims description 2
- 239000011247 coating layer Substances 0.000 claims description 2
- 238000002601 radiography Methods 0.000 claims description 2
- 210000004204 blood vessel Anatomy 0.000 abstract description 10
- 230000000694 effects Effects 0.000 abstract description 6
- 230000015572 biosynthetic process Effects 0.000 abstract description 5
- 238000001647 drug administration Methods 0.000 abstract description 5
- 238000000576 coating method Methods 0.000 abstract description 4
- 210000003137 popliteal artery Anatomy 0.000 description 4
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 238000010147 laser engraving Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 208000002847 Surgical Wound Diseases 0.000 description 2
- 230000002785 anti-thrombosis Effects 0.000 description 2
- 230000001112 coagulating effect Effects 0.000 description 2
- 239000011248 coating agent Substances 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 230000002966 stenotic effect Effects 0.000 description 2
- 210000002465 tibial artery Anatomy 0.000 description 2
- 206010014513 Embolism arterial Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 208000034158 bleeding Diseases 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000002302 brachial artery Anatomy 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 210000003414 extremity Anatomy 0.000 description 1
- 210000001105 femoral artery Anatomy 0.000 description 1
- 238000002695 general anesthesia Methods 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0021—Catheters; Hollow probes characterised by the form of the tubing
- A61M25/0023—Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M25/0045—Catheters; Hollow probes characterised by structural features multi-layered, e.g. coated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
- A61M25/007—Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22082—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance
- A61B2017/22084—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance stone- or thrombus-dissolving
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M2025/0008—Catheters; Hollow probes having visible markings on its surface, i.e. visible to the naked eye, for any purpose, e.g. insertion depth markers, rotational markers or identification of type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M2025/0057—Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
Abstract
The invention provides a core-free thrombolytic catheter, which is used for conveying thrombolytic drugs of drug administration equipment to the periphery of thrombus for perfusion in catheterization and is characterized by comprising the following components in sequence: the connecting end is provided with a thread structure and is connected with the drug administration equipment; a delivery segment for delivering thrombolytic drugs; a perfusion section, the wall of which is provided with a penetrating structure for perfusing thrombolytic drugs around thrombus; the head end is provided with a first closing piece and a second closing piece, edges of the first closing piece and the second closing piece are attached to each other, so that the head end is sealed, and heparin coatings are arranged on the outer walls of the conveying section, the pouring section and the head end. The thrombolysis catheter of the invention does not need to use an inner core, can be manufactured into a thinner outer diameter, can be applied to thinner blood vessels, can reduce the occupying effect and prevent the formation of new thrombus.
Description
Technical Field
The invention belongs to the field of medical instruments, and relates to a medical thrombolysis catheter, in particular to a core-free thrombolysis catheter.
Background
Catheter contact thrombolysis (abbreviated as catheterization) is a method for treating intravascular thrombus by directly infusing high-concentration thrombolytic drugs around the thrombus through a thrombolytic catheter to dissolve the thrombus and achieve the therapeutic purpose. Compared with the traditional modes of catheter thrombus extraction and the like, the Guan Rong thrombus extraction does not need general anesthesia, has small operation wound, can avoid repeated dragging of the catheter in the blood vessel and reduces the damage to the blood vessel, thus being an ideal thrombus treatment method.
The thrombolysis catheter in the prior art is usually a sleeve type catheter and comprises a catheter main body and a matched inner core, wherein the catheter main body is a hollow tube made of medical plastic, and the diameter of the head end of the catheter main body is reduced and is similar to a cone shape; the pouring section is close to the head end, the length is generally 10-50 cm, and a plurality of pouring holes formed by laser engraving are distributed; the infusion section is also connected with a conveying section which is longer and has no infusion hole and other structures, and a connecting end which is connected with the conveying section and is used for connecting the drug delivery equipment.
During treatment, a guide wire is inserted from the incision, guided to the thrombus position, then the catheter main body is sleeved on the guide wire, and the catheter main body is guided into the thrombus position. And then the guide wire is extracted and inserted into the inner core, then the connecting end is connected with the drug delivery equipment, and the thrombolytic drug can be released in the perfusion section after being pumped in, so that the thrombolytic drug is perfused into the thrombus. Because the diameter of the head end of the main body is reduced, the inner core can be only accommodated, the inner core just seals the head end, and the medicine can not overflow from the head end but is only released at the perfusion section, so that the aim of fixed-point and uniform medicine administration is achieved.
In the thrombolytic catheter described above, in order for the catheter body to be able to pass through the guidewire, its head end must be of open construction; in order to prevent the liquid medicine from flowing out of the head end during the administration, the head end must be closed by an inner core. Therefore, the inner core of such thrombolytic catheters is indispensable; in order to ensure the administration, a certain gap is needed between the inner core and the catheter main body, and in order to ensure the strength, the wall of the catheter main body cannot be made to be too thin. Under the superposition of various factors, the outer diameter of the finest thrombolytic catheter reaches 3F, and the catheter is difficult to be applied to finer blood vessels such as branch arteries below knee. In addition, because the thrombolysis catheter is thicker, the space occupying effect is obvious after entering the blood vessel, so that the blood is difficult to smoothly enter the affected limb, and the risk of aggravating the illness state is caused.
In addition, the thrombolytic catheter may block blood flow on the healthy side after entering the human body, and induce the formation of new thrombus. The catheter body is usually made of medical plastic, and the inner core is usually made of metal, so that the possibility of thrombus formation is increased even more after the catheter body is taken into a blood vessel as a foreign body. To avoid this, it is common practice in the clinic to increase the amount of thrombolytic drug to prevent the formation of new thrombi, which not only increases the medical costs of the patient, but also increases the risk of bleeding in the patient.
Disclosure of Invention
In order to solve the problems, the invention provides a thrombolytic catheter which does not have an inner core and can prevent new thrombosis, and the invention adopts the following technical scheme:
the invention provides a core-free thrombolytic catheter, which is used for conveying thrombolytic drugs of drug administration equipment to the periphery of thrombus for perfusion in catheterization and is characterized by comprising the following components in sequence: the connecting end is provided with a thread structure and is connected with the drug administration equipment; a delivery segment for delivering thrombolytic drugs; a perfusion section, the wall of which is provided with a penetrating structure for perfusing thrombolytic drugs around thrombus; the head end is provided with a first closing piece and a second closing piece, edges of the first closing piece and the second closing piece are attached to each other, so that the head end is sealed, and heparin coatings are arranged on the outer walls of the conveying section, the pouring section and the head end.
The coreless thrombolysis catheter provided by the invention can also have the following technical characteristics: the penetrating structure is a penetrating hole or a penetrating crack arranged on the pipe wall.
The coreless thrombolysis catheter provided by the invention can also have the following technical characteristics: the two ends of the perfusion segment are also provided with marking parts which are made of X-ray impermeable materials and are used for carrying out radiography positioning on the perfusion segment under the condition of X rays.
The coreless thrombolysis catheter provided by the invention can also have the following technical characteristics: wherein the length of the conveying section is 100 cm-150 cm.
The coreless thrombolysis catheter provided by the invention can also have the following technical characteristics: wherein the length of the pouring section is 5 cm-50 cm.
The coreless thrombolysis catheter provided by the invention can also have the following technical characteristics: wherein, the outer diameter of the head end, the perfusion section and the delivery section is the same, and the minimum outer diameter is 0.66mm.
The coreless thrombolysis catheter provided by the invention can also have the following technical characteristics: the first closing piece and the second closing piece are symmetrical flat pieces, so that the head end presents a duckbill structure.
The actions and effects of the invention
According to the coreless thrombolysis catheter provided by the invention, as the head end adopts a mode that two closing sheets are closed for sealing, when the catheter is used, the catheter can be opened by lightly pinching to enable the guide wire to be inserted, and after the guide wire is pulled out, the two closing sheets can be restored to seal the head end, so that the core is not required to be used for sealing the head end, the core-less thrombolysis catheter can be manufactured into a thinner outer diameter, can be applied to thinner blood vessels, can reduce the occupation effect, and can prevent the formation of new thrombus. In addition, the heparin coating is arranged on the outer wall of the catheter, so that blood can be prevented from coagulating on the outer wall, and the catheter has good antithrombotic effect without increasing the dosage.
Drawings
FIG. 1 is a schematic structural view of a coreless thrombolytic catheter of the present invention;
FIG. 2 is a schematic illustration of a coreless thrombolysis catheter application in accordance with a first embodiment of the present invention;
fig. 3 is a schematic illustration of the application of a coreless thrombolytic catheter in accordance with a second embodiment of the present invention.
Detailed Description
The following describes specific embodiments of the present invention with reference to the drawings and examples.
Example 1
FIG. 1 is a schematic structural view of the coreless thrombolytic catheter of the present invention.
As shown in fig. 1, a coreless thrombolysis catheter (hereinafter referred to as thrombolysis catheter) 10 of the present invention is generally tubular and includes a connection end 4, a delivery section 3, a perfusion section 2 and a head end 1.
The outer wall of the connecting end 4 is provided with a thread structure and is used for being connected with the drug delivery device; the conveying section 3 is used for conveying thrombolytic drugs pumped by the drug delivery equipment; the wall of the perfusion segment 2 is provided with a penetrating structure for releasing thrombolytic drugs. In the embodiment, the length of the pouring section 2 is 30cm, and the penetrating structure on the wall is a plurality of penetrating holes formed by laser engraving; the outer diameters of the conveying section 3 and the pouring section 2 are the same and are 2F; the total length of the delivery segment 3, the perfusion segment 2 and the head end 1 is 100cm, that is, the total length of the thrombolytic catheter 10 is about 100cm. In addition, heparin coating layers are arranged on the outer walls of the conveying section 3, the pouring section 2 and the head end 1.
The head end 1 comprises a first closing tab 11 and a second closing tab 12, in the form of symmetrical flat sheets. The edges of the first closing tab 11 and the second closing tab 12 are in contact, causing the head end 1 to be closed and assume a duckbill-like configuration.
In this embodiment, two marking portions 21 are also provided at the two ends of the perfusion segment 2, respectively, made of an X-ray opaque material, for contrast positioning of the perfusion segment 2 under X-ray conditions.
The application of the coreless thrombolytic catheter of this embodiment is described below with reference to the accompanying drawings.
Fig. 2 is a schematic illustration of a coreless thrombolytic catheter application in accordance with a first embodiment of the present invention.
As shown in fig. 2, the patient involved in this example is an acute arterial embolism patient, and thrombus is mainly concentrated in the left popliteal artery and the posterior tibial artery. The surgical incision is selected at the right femoral artery and the blood vessel of the thrombus site is thin, so that a thrombolysis catheter having a relatively short overall length and a thin diameter, i.e., the thrombolysis catheter 10 according to the first embodiment, needs to be selected.
After the guide wire is introduced from the vascular incision, the thrombolytic catheter 10 of the first embodiment is introduced, and the perfusion segment 2 is precisely positioned according to the marker 21 under the X-ray so as to just reach the left popliteal artery and the posterior tibial artery where thrombus is concentrated. At this time, the connecting end 4 and a part of the delivery segment 3 are left outside the body, and after the external part is fixed, the connecting end 4 can be connected with the drug administration device 20, and the thrombolytic drug is continuously delivered and infused to the thrombus site.
Example operation and Effect
According to the coreless thrombolysis catheter provided by the embodiment, as the head end adopts the mode that the two closing sheets are closed to be closed, the two closing sheets can be opened to enable the guide wire to be inserted when the thrombolysis catheter is in use, and the head end is closed after the guide wire is pulled out, the head end of the thrombolysis catheter does not need to be closed by using the inner core, the thrombolysis catheter can be manufactured into a thinner outer diameter, can be applied to thinner blood vessels, can reduce the occupation effect and prevent new thrombosis. The thrombolytic catheter of the embodiment is provided with the heparin coating on the outer wall, so that the blood can be prevented from coagulating on the outer wall, and the thrombolytic catheter has good antithrombotic effect without increasing the dosage.
In addition, in the thrombolytic catheter of the embodiment, the two ends of the perfusion segment are provided with the marking parts, and the marking parts are made of materials which are not transparent to X rays, so that the contrast positioning can be realized under the X rays, and the perfusion segment is conveniently guided to the thrombus position.
< example two >
In the second embodiment, the same components as those in the first embodiment are given the same reference numerals, and the same description is omitted.
In this embodiment, the total length of the thrombolytic catheter 10 is about 150cm; the length of the pouring section 2 is 30cm, and a penetrating crack structure formed by laser engraving is arranged on the wall. The outer diameters of the conveying section 3 and the pouring section 2 are the same and are 3F.
The application of the thrombolytic catheter of this embodiment is described below with reference to the drawings.
Fig. 3 is a schematic illustration of the application of a coreless thrombolytic catheter in accordance with a second embodiment of the present invention.
As shown in FIG. 3, the patient according to this example was a right popliteal artery stenotic thrombosis patient, and a large number of thrombi were formed on the basis of examination of the popliteal artery stenotic lesions. Since the surgical incision is selected at the left brachial artery, a relatively long thrombolytic catheter needs to be selected; in addition, since the thrombus site is located at a relatively thick blood vessel, a thrombolytic catheter having a slightly larger diameter, that is, in this embodiment, a thrombolytic catheter 10 having a diameter of 3F and a total length of about 150cm, can be selected. The other operation procedures are the same as those of the first embodiment, and will not be described again.
The above examples are only for illustrating the embodiments of the present invention, and are not intended to limit the scope of the present invention. It will be apparent to those skilled in the art that various changes can be made within the spirit and scope of the invention as defined and defined by the following claims, all of which are within the scope of the invention as defined by the appended claims.
Claims (5)
1. A coreless thrombolytic catheter for delivering thrombolytic drugs of a drug delivery device to a surrounding of a thrombus for infusion during catheterization, comprising, in order:
the connecting end is provided with a thread structure and is connected with the drug delivery device;
a delivery segment for delivering the thrombolytic drug;
a perfusion section, the wall of which is provided with a penetrating structure for perfusing the thrombolytic drug around thrombus;
a head end provided with a first closing sheet and a second closing sheet, wherein the edges of the first closing sheet and the second closing sheet are jointed, so that the head end is closed,
wherein the outer walls of the conveying section, the pouring section and the head end are all provided with heparin coating layers,
the penetrating structure is a penetrating hole or a penetrating crack arranged on the pipe wall,
the first closure flap and the second closure flap are symmetrical, flat flaps such that the head end presents a duckbill configuration.
2. The coreless thrombolytic catheter of claim 1, wherein:
the two ends of the perfusion segment are also provided with marking parts which are made of X-ray impermeable materials and are used for carrying out radiography positioning on the perfusion segment under the condition of X rays.
3. The coreless thrombolytic catheter of claim 1, wherein:
wherein the length of the conveying section is 100 cm-150 cm.
4. The coreless thrombolytic catheter of claim 1, wherein:
wherein the length of the pouring section is 5 cm-50 cm.
5. The coreless thrombolytic catheter of claim 1, wherein:
wherein the outer diameters of the pouring section and the conveying section are the same, and the minimum outer diameter is 0.66mm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711114153.9A CN107789719B (en) | 2017-11-13 | 2017-11-13 | Inner core-free thrombolysis catheter |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711114153.9A CN107789719B (en) | 2017-11-13 | 2017-11-13 | Inner core-free thrombolysis catheter |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107789719A CN107789719A (en) | 2018-03-13 |
| CN107789719B true CN107789719B (en) | 2024-04-02 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711114153.9A Active CN107789719B (en) | 2017-11-13 | 2017-11-13 | Inner core-free thrombolysis catheter |
Country Status (1)
| Country | Link |
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| CN (1) | CN107789719B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109200441A (en) * | 2018-11-01 | 2019-01-15 | 郑州大学第附属医院 | A kind of thrombolysis catheter device through jugular vein treatment thrombus |
| CN109731205A (en) * | 2018-12-11 | 2019-05-10 | 中国人民解放军总医院 | A kind of thrombolysis catheter device |
| CN110180072A (en) * | 2019-06-26 | 2019-08-30 | 高峰 | A kind of thrombolysis pipe and thrombolysis tube assembly |
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| US6635027B1 (en) * | 1997-05-19 | 2003-10-21 | Micro Therepeutics, Inc. | Method and apparatus for intramural delivery of a substance |
| CN104586473A (en) * | 2015-02-16 | 2015-05-06 | 田进文 | Rapid exchange double-lumen micro catheter for reverse thrombolysis and use method thereof |
| CN205073480U (en) * | 2015-10-14 | 2016-03-09 | 乐普（北京）医疗器械股份有限公司 | Dissolve and tie pipe installation |
| CN106859729A (en) * | 2017-03-10 | 2017-06-20 | 上海心玮医疗科技有限公司 | One kind takes bolt mounting system |
| CN107206207A (en) * | 2015-01-09 | 2017-09-26 | 阿克瑞特医学治疗有限公司 | Embolism microtubular |
| CN107281619A (en) * | 2017-08-03 | 2017-10-24 | 毕国善 | Thrombolysis catheter |
| CN209253893U (en) * | 2017-11-13 | 2019-08-16 | 上海长海医院 | Without belly core thrombolysis catheter |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6755813B2 (en) * | 2001-11-20 | 2004-06-29 | Cleveland Clinic Foundation | Apparatus and method for performing thrombolysis |
| WO2010091376A2 (en) * | 2009-02-08 | 2010-08-12 | Blaise Baxter | Devices and methods for perfusion therapy |
| US9820761B2 (en) * | 2014-03-21 | 2017-11-21 | Route 92 Medical, Inc. | Rapid aspiration thrombectomy system and method |
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2017
- 2017-11-13 CN CN201711114153.9A patent/CN107789719B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6635027B1 (en) * | 1997-05-19 | 2003-10-21 | Micro Therepeutics, Inc. | Method and apparatus for intramural delivery of a substance |
| CN107206207A (en) * | 2015-01-09 | 2017-09-26 | 阿克瑞特医学治疗有限公司 | Embolism microtubular |
| CN104586473A (en) * | 2015-02-16 | 2015-05-06 | 田进文 | Rapid exchange double-lumen micro catheter for reverse thrombolysis and use method thereof |
| CN205073480U (en) * | 2015-10-14 | 2016-03-09 | 乐普（北京）医疗器械股份有限公司 | Dissolve and tie pipe installation |
| CN106859729A (en) * | 2017-03-10 | 2017-06-20 | 上海心玮医疗科技有限公司 | One kind takes bolt mounting system |
| CN107281619A (en) * | 2017-08-03 | 2017-10-24 | 毕国善 | Thrombolysis catheter |
| CN209253893U (en) * | 2017-11-13 | 2019-08-16 | 上海长海医院 | Without belly core thrombolysis catheter |
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| Publication number | Publication date |
|---|---|
| CN107789719A (en) | 2018-03-13 |
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