CN110180072A - A kind of thrombolysis pipe and thrombolysis tube assembly - Google Patents
A kind of thrombolysis pipe and thrombolysis tube assembly Download PDFInfo
- Publication number
- CN110180072A CN110180072A CN201910561226.1A CN201910561226A CN110180072A CN 110180072 A CN110180072 A CN 110180072A CN 201910561226 A CN201910561226 A CN 201910561226A CN 110180072 A CN110180072 A CN 110180072A
- Authority
- CN
- China
- Prior art keywords
- thrombolysis
- seal wire
- pipe
- section
- thrombolysis pipe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000002537 thrombolytic effect Effects 0.000 title claims abstract description 87
- 230000008676 import Effects 0.000 claims abstract description 6
- 239000011248 coating agent Substances 0.000 claims description 12
- 238000000576 coating method Methods 0.000 claims description 12
- 239000003146 anticoagulant agent Substances 0.000 claims description 9
- 229940127219 anticoagulant drug Drugs 0.000 claims description 9
- 230000008602 contraction Effects 0.000 claims description 8
- 230000000845 anti-microbial effect Effects 0.000 claims description 7
- 239000007924 injection Substances 0.000 claims description 6
- 238000002347 injection Methods 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 5
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 claims description 3
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 3
- 229960002897 heparin Drugs 0.000 claims description 3
- 229920000669 heparin Polymers 0.000 claims description 3
- 229910052709 silver Inorganic materials 0.000 claims description 3
- 239000004332 silver Substances 0.000 claims description 3
- 208000007536 Thrombosis Diseases 0.000 abstract description 23
- 230000000712 assembly Effects 0.000 abstract description 2
- 238000000429 assembly Methods 0.000 abstract description 2
- 210000004204 blood vessel Anatomy 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 239000012530 fluid Substances 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 4
- 239000003527 fibrinolytic agent Substances 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 238000006911 enzymatic reaction Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 230000000875 corresponding effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000013467 fragmentation Methods 0.000 description 1
- 238000006062 fragmentation reaction Methods 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000010297 mechanical methods and process Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M25/0045—Catheters; Hollow probes characterised by structural features multi-layered, e.g. coated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M25/005—Catheters; Hollow probes characterised by structural features with embedded materials for reinforcement, e.g. wires, coils, braids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/091—Guide wires having a lumen for drug delivery or suction
Abstract
The invention discloses a kind of thrombolysis pipe and thrombolysis tube assemblies, thrombolysis pipe in the present invention is when general seal wire is inserted into the thrombolysis pipe, the general seal wire can close the import of the seal wire fixed knob and the outlet of the closed section, and have administration gap between the inner wall of the active section and the general seal wire.That is, general seal wire is able to use using thrombolysis pipe of the invention, without the non-universal seal wire of higher operating costs, it will be able to complete the purpose being smoothly administered, the cost of thrombolysis tube assembly when reducing the treatment of clinical thrombus, to reduce the treatment cost of clinical thrombus.
Description
Technical field
The present invention relates to the field of medical instrument technology, more specifically to a kind of thrombolysis pipe and thrombolysis tube assembly.
Background technique
There are three ways to clinically more commonly treating thrombus, the first is artificial Mechanical Method, passes through surgical operation
Or suction unit takes out endovascular thrombus.Second is that implantation bracket expands intravascular space.The third is thrombolytic drug
Cure is gradually dissolved thrombus by injection thrombolytic drug, to achieve the purpose that blood vessel is connected.Wherein, thrombolytic drug therapy
Method usually requires to use thrombolysis tube assembly, and thrombolysis tube assembly is usually directed to thrombolysis pipe and seal wire.
In thrombolysis pipe when indwelling seal wire, could smoothly it be administered due to there must be gap in seal wire and thrombolysis pipe, lead to
With seal wire can not normal use, need the non-universal seal wire that special design agents are thinner, and the head end of the non-universal seal wire will add
Sealing process could be played to thrombolysis tube head end by slightly arriving general seal wire size 0.035``, and drug could pass through the side opening of thrombolysis pipe
Outflow, to come into full contact with thrombus.And non-universal seal wire is thinner compared to general seal wire integral diameter, compared to the general seal wire of processing
Mature equipment and technology for, the process equipment and technology of non-universal seal wire, difficulty is bigger, to directly increase molten
The production cost of bolt tube assembly further increases the treatment cost of clinical thrombus.
Therefore, the treatment cost for how reducing clinical thrombus, is a problem to be solved by those skilled in the art.
Summary of the invention
In view of this, the technical problem to be solved by the present invention is to how reduce the treatment cost of clinical thrombus, for this purpose, this
Invention provides a kind of thrombolysis pipe and thrombolysis tube assembly.
To achieve the above object, the invention provides the following technical scheme:
A kind of thrombolysis pipe, including the closed section, active section and fixed section being sequentially arranged by head end to tail end, wherein described
Active section is provided with liquid injection port and side opening, and the fixed section is removably provided with seal wire fixed knob, when general seal wire is inserted into
When to the thrombolysis pipe, the general seal wire can close the import of the seal wire fixed knob and the outlet of the closed section,
And there is administration gap between the inner wall of the active section and the general seal wire.
The present invention in one embodiment, further include that the outer active section described without leave is gradually smaller to the closed section
First contraction section.
The present invention in one embodiment, further include that the outer fixed section described without leave is gradually smaller to the active section
Second contraction section.
The present invention in one embodiment, the active section is identical with the internal diameter of the fixed section.
The present invention in one embodiment, the outer surface of the thrombolysis pipe is provided with antimicrobial coating.
The present invention in one embodiment, the antimicrobial coating be silver coating.
The present invention in one embodiment, the outer surface of the thrombolysis pipe is provided with anticoagulant layer.
The present invention in one embodiment, the anticoagulant layer be heparin layer.
The invention also discloses a kind of thrombolysis tube assembly, including thrombolysis pipe as described in any one of the above embodiments and be inserted into
General seal wire in the thrombolysis pipe.
The present invention in one embodiment, further include the coiled wire being inserted into in the thrombolysis pipe.
It can be seen from the above technical scheme that the thrombolysis pipe in the present invention is inserted into the thrombolysis pipe in general seal wire
When, the general seal wire can close the import of the seal wire fixed knob and the outlet of the closed section, and the active section
Inner wall and the general seal wire between have administration gap.That is, being able to use using thrombolysis pipe of the invention general
Seal wire, without the non-universal seal wire of higher operating costs, it will be able to complete the purpose being smoothly administered, reduce clinical thrombus
Treatment when thrombolysis tube assembly cost, to reduce the treatment cost of clinical thrombus.
Detailed description of the invention
In order to more clearly explain the embodiment of the invention or the technical proposal in the existing technology, to embodiment or will show below
There is attached drawing needed in technical description to be briefly described, it should be apparent that, the accompanying drawings in the following description is only this
Some embodiments of invention for those of ordinary skill in the art without creative efforts, can be with
It obtains other drawings based on these drawings.
Fig. 1 is a kind of overlooking structure diagram of thrombolysis pipe provided by the embodiment of the present invention；
Fig. 2 is a kind of partial structural diagram of thrombolysis pipe provided by the embodiment of the present invention.
In figure, 100 it is thrombolysis pipe, 101 is closed section, 102 is active section, 103 is fixed section, 104 is liquid injection port, 105
For side opening, 106 seal wire fixed knobs, 107 the first contraction sections, 108 the second contraction sections, 200 be seal wire, 300 be blood vessel,
400 be thrombus.
Specific embodiment
For the technical description that has powerful connections it is found that in current thrombolysis tube assembly, the caliber of thrombolysis pipe is 5F (3F is about 1mm), and
Compatible therewith is non-universal seal wire, and the diameter of the head end of the non-universal seal wire is 0.035``, and main part is thinner,
When can guarantee that the non-universal seal wire is inserted into thrombolysis pipe, there are gaps between non-universal seal wire and thrombolysis pipe.In this way, passing through note
When liquid mouth carries out fluid injection, drug can pass through above-mentioned gap and be come into full contact with by side opening and thrombus.And non-universal seal wire
Manufacturing cost is much higher than the manufacturing cost of general seal wire.Since the size of non-universal seal wire and non-universal seal wire size be not general,
Therefore, non-universal seal wire should not be reused, and cause instrument waste.
For this purpose, core of the invention is to provide a kind of thrombolysis pipe and thrombolysis tube assembly, to reduce controlling for clinical thrombus
Treat cost.
In addition, embodiments illustrated below does not play any restriction effect to the invention described in the claims content.In addition,
The full content of composition represented by following example is not limited to must as the solution of the invention described in the claims
It needs.
Please refer to Fig. 1 to Fig. 2, the thrombolysis pipe 100 in the embodiment of the present invention, including the envelope being sequentially arranged by head end to tail end
Close section 101, active section 102 and fixed section 103, wherein active section 102 is provided with liquid injection port 104 and side opening 105, fixed section 103
It removably is provided with seal wire fixed knob 106, when general seal wire 200 is inserted into thrombolysis pipe 100, general seal wire 200 can
The import of seal wire fixed knob 106 and the outlet of closed section 101 are closed, and between the inner wall of active section 102 and general seal wire 200
With administration gap.
When general seal wire 200 is inserted into thrombolysis pipe 100, general seal wire 200 can be closed thrombolysis pipe 100 in the present invention
The import of seal wire fixed knob 106 and the outlet of closed section 101, and have between the inner wall of active section 102 and general seal wire 200
Gap is administered.That is, be able to use general seal wire 200 using thrombolysis pipe 100 of the invention, without use cost compared with
High non-universal seal wire, it will be able to complete the purpose being smoothly administered, thrombolysis tube assembly when reducing the treatment of clinical thrombus 400
Cost, to reduce the treatment cost of clinical thrombus 400.
In addition, in the prior art, the size of thrombolysis pipe 100 is 5F, therefore, medical fluid has biggish when passing through side opening 105
Pressure sprays side opening 105 sufficiently to contact with thrombus 400.And in the application, due to using general seal wire 200, it is equivalent to increasing
The diameter of 100 active section 102 of thrombolysis pipe is added, when medical fluid passes through side opening 105, pressure is smaller compared to the prior art, slowly sprays
It is contacted out with thrombus 400, and being relatively large in diameter due to 100 active section 102 of thrombolysis pipe, increases medical fluid and thrombus 400 is effective
Contact area, enzymatic reaction is directly proportional to contact area, so as to improve therapeutic effect.
Due to being able to use general seal wire 200 using the thrombolysis pipe 100, and general seal wire 200 can be reused, thus
Reduce the waste of general seal wire 200.
Need to illustrate when, the diameter of the active section 102 of thrombolysis pipe 100 is compared to thrombolysis pipe in the prior art in this case
100 diameter increased, general using the size for being greater than 6F.
In order to reduce the resistance when thrombolysis pipe 100 insertion, the thrombolysis pipe 100 in the present invention further includes outer active section without leave
102 to gradually smaller first contraction section 107 of closed section 101.Therefore, active section 102 and closed section 101 can have smoother
Transition, to reduce resistance when being inserted at blood vessel 300.
It similarly, further include outer diameter self-retaining section 103 to gradually smaller second contraction section 108 of active section 102.
Above-mentioned active section 102 is identical with the internal diameter of fixed section 103 or internal diameter is different, preferably uses the identical side of internal diameter
Formula facilitates processing.
Since thrombolysis pipe 100 is long in the residence time of blood vessel 300, the outer surface of thrombolysis pipe 100 is provided with anti-
Bacterium coating.The probability of bacteria breed can be reduced by the way that antimicrobial coating is arranged, to reduce the risk of infection, extend thrombolysis pipe
100 residence time.The antimicrobial coating is the coating that anti-biotic material is process, such as the antimicrobial coating is silver coating.
In addition, thrombolysis pipe 100 in blood vessel 300 for a long time and contacting blood, therefore, the outer surface of thrombolysis pipe 100 is provided with
Anticoagulant layer.The probability of blood clotting can be reduced by the way that anticoagulant layer is arranged.The anticoagulant layer is process by anticoagulant material, example
Such as anticoagulant layer is heparin layer.
The invention also discloses a kind of thrombolysis tube assemblies, the thrombolysis pipe 100 including such as any of the above-described and be inserted into
General seal wire 200 in thrombolysis pipe 100.Since above-mentioned thrombolysis pipe 100 has the above beneficial effect, including the thrombolysis pipe 100
Thrombolysis tube assembly has corresponding effect, and details are not described herein again.
It further, further include the coiled wire 200 being inserted into in thrombolysis pipe 100.The diameter of the coiled wire 200
For the diameter of general seal wire 200, as 0.035``.Since the diameter of the coiled wire 200 is that its hardness of 0.035`` can protect
Card, when being inserted into thrombolysis pipe 100 using the coiled wire 200, since coiled wire 200 has helical structure, energy
It enough drives thrombolysis pipe 100 to generate helix-deformed, generates fragmentation so as to stir the thrombus 400 at blood vessel 300, further
The contact area of thrombolysis pipe 100 and thrombus 400, medical fluid and thrombus 400 is increased, the enzymatic reaction of thrombus 400 is accelerated.
The foregoing description of the disclosed embodiments enables those skilled in the art to implement or use the present invention.
Various modifications to these embodiments will be readily apparent to those skilled in the art, as defined herein
General Principle can be realized in other embodiments without departing from the spirit or scope of the present invention.Therefore, of the invention
It is not intended to be limited to the embodiments shown herein, and is to fit to and the principles and novel features disclosed herein phase one
The widest scope of cause.
Claims (10)
1. a kind of thrombolysis pipe, which is characterized in that including the closed section, active section and fixed section being sequentially arranged by head end to tail end,
Wherein, the active section is provided with liquid injection port and side opening, and the fixed section is removably provided with seal wire fixed knob, when general
When seal wire is inserted into the thrombolysis pipe, the general seal wire can close the seal wire fixed knob import and the closed section
Outlet, and between the inner wall of the active section and the general seal wire have administration gap.
2. thrombolysis pipe as described in claim 1, which is characterized in that further include the outer active section described without leave to the closed section by
The first small contraction section of gradual change.
3. thrombolysis pipe as claimed in claim 2, which is characterized in that further include the outer fixed section described without leave to the active section by
The second small contraction section of gradual change.
4. thrombolysis pipe as claimed in claim 3, which is characterized in that the active section is identical with the internal diameter of the fixed section.
5. thrombolysis pipe as described in claim 1, which is characterized in that the outer surface of the thrombolysis pipe is provided with antimicrobial coating.
6. thrombolysis pipe as claimed in claim 5, which is characterized in that the antimicrobial coating is silver coating.
7. thrombolysis pipe as described in claim 1, which is characterized in that the outer surface of the thrombolysis pipe is provided with anticoagulant layer.
8. thrombolysis pipe as claimed in claim 7, which is characterized in that the anticoagulant layer is heparin layer.
9. a kind of thrombolysis tube assembly, which is characterized in that including thrombolysis pipe such as described in any item of the claim 1 to 8 and can
The general seal wire being inserted into the thrombolysis pipe.
10. thrombolysis tube assembly as claimed in claim 9, which is characterized in that further include being inserted into the thrombolysis pipe
Coiled wire.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910561226.1A CN110180072A (en) | 2019-06-26 | 2019-06-26 | A kind of thrombolysis pipe and thrombolysis tube assembly |
| PCT/CN2020/086906 WO2020259053A1 (en) | 2019-06-26 | 2020-04-26 | Thrombolysis catheter and thrombolysis catheter assembly |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910561226.1A CN110180072A (en) | 2019-06-26 | 2019-06-26 | A kind of thrombolysis pipe and thrombolysis tube assembly |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110180072A true CN110180072A (en) | 2019-08-30 |
Family
ID=67723636
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910561226.1A Pending CN110180072A (en) | 2019-06-26 | 2019-06-26 | A kind of thrombolysis pipe and thrombolysis tube assembly |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN110180072A (en) |
| WO (1) | WO2020259053A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020259053A1 (en) * | 2019-06-26 | 2020-12-30 | 高峰 | Thrombolysis catheter and thrombolysis catheter assembly |
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| US5228452A (en) * | 1992-02-19 | 1993-07-20 | Target Therapeutics Inc. | Proximal end fitting with an improved seal for use in a catheter guidewire assembly |
| US5417689A (en) * | 1994-01-18 | 1995-05-23 | Cordis Corporation | Thermal balloon catheter and method |
| US5833706A (en) * | 1991-07-05 | 1998-11-10 | Scimed Life Systems, Inc. | Single operator exchange perfusion catheter having a distal catheter shaft section |
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-
2019
- 2019-06-26 CN CN201910561226.1A patent/CN110180072A/en active Pending
-
2020
- 2020-04-26 WO PCT/CN2020/086906 patent/WO2020259053A1/en active Application Filing
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|---|---|---|---|---|
| US5833706A (en) * | 1991-07-05 | 1998-11-10 | Scimed Life Systems, Inc. | Single operator exchange perfusion catheter having a distal catheter shaft section |
| US5228452A (en) * | 1992-02-19 | 1993-07-20 | Target Therapeutics Inc. | Proximal end fitting with an improved seal for use in a catheter guidewire assembly |
| US5417689A (en) * | 1994-01-18 | 1995-05-23 | Cordis Corporation | Thermal balloon catheter and method |
| US5843050A (en) * | 1995-11-13 | 1998-12-01 | Micro Therapeutics, Inc. | Microcatheter |
| CN2408878Y (en) * | 2000-03-02 | 2000-12-06 | 霍新明 | Urinary catheter |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020259053A1 (en) * | 2019-06-26 | 2020-12-30 | 高峰 | Thrombolysis catheter and thrombolysis catheter assembly |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020259053A1 (en) | 2020-12-30 |
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