CN107789214A - A kind of acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue and preparation method thereof - Google Patents
A kind of acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue and preparation method thereof Download PDFInfo
- Publication number
- CN107789214A CN107789214A CN201711094248.9A CN201711094248A CN107789214A CN 107789214 A CN107789214 A CN 107789214A CN 201711094248 A CN201711094248 A CN 201711094248A CN 107789214 A CN107789214 A CN 107789214A
- Authority
- CN
- China
- Prior art keywords
- wet tissue
- quaternary ammonium
- ammonium salt
- acrylic acid
- nonwoven fabric
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000004745 nonwoven fabric Substances 0.000 title claims abstract description 66
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 title claims abstract description 62
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 title claims abstract description 61
- 238000002360 preparation method Methods 0.000 title claims description 54
- 239000007788 liquid Substances 0.000 claims abstract description 55
- -1 alkyl glucosides Chemical class 0.000 claims abstract description 15
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 13
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical class CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 claims abstract description 13
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims abstract description 11
- 229930182478 glucoside Natural products 0.000 claims abstract description 11
- 239000000787 lecithin Substances 0.000 claims abstract description 11
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- 235000010445 lecithin Nutrition 0.000 claims abstract description 11
- 239000003643 water by type Substances 0.000 claims abstract description 11
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 claims abstract description 10
- 239000000654 additive Substances 0.000 claims abstract description 9
- 230000003750 conditioning effect Effects 0.000 claims abstract description 9
- 239000000178 monomer Substances 0.000 claims description 24
- 238000006243 chemical reaction Methods 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 10
- 229910052757 nitrogen Inorganic materials 0.000 claims description 10
- 230000001954 sterilising effect Effects 0.000 claims description 9
- 238000004659 sterilization and disinfection Methods 0.000 claims description 9
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 8
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims description 7
- 235000017491 Bambusa tulda Nutrition 0.000 claims description 7
- 241001330002 Bambuseae Species 0.000 claims description 7
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims description 7
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims description 7
- 239000011425 bamboo Substances 0.000 claims description 7
- PYIDGJJWBIBVIA-UYTYNIKBSA-N lauryl glucoside Chemical compound CCCCCCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O PYIDGJJWBIBVIA-UYTYNIKBSA-N 0.000 claims description 7
- 229940048848 lauryl glucoside Drugs 0.000 claims description 7
- 229910004664 Cerium(III) chloride Inorganic materials 0.000 claims description 6
- 150000001252 acrylic acid derivatives Chemical class 0.000 claims description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 6
- 150000001875 compounds Chemical class 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 5
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- 238000003756 stirring Methods 0.000 claims description 5
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- 238000006386 neutralization reaction Methods 0.000 claims description 4
- 238000007654 immersion Methods 0.000 claims description 3
- 239000004475 Arginine Substances 0.000 claims description 2
- JEBFVOLFMLUKLF-IFPLVEIFSA-N Astaxanthin Natural products CC(=C/C=C/C(=C/C=C/C1=C(C)C(=O)C(O)CC1(C)C)/C)C=CC=C(/C)C=CC=C(/C)C=CC2=C(C)C(=O)C(O)CC2(C)C JEBFVOLFMLUKLF-IFPLVEIFSA-N 0.000 claims description 2
- 239000004322 Butylated hydroxytoluene Substances 0.000 claims description 2
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 claims description 2
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 claims description 2
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 claims description 2
- QNVSXXGDAPORNA-UHFFFAOYSA-N Resveratrol Natural products OC1=CC=CC(C=CC=2C=C(O)C(O)=CC=2)=C1 QNVSXXGDAPORNA-UHFFFAOYSA-N 0.000 claims description 2
- LUKBXSAWLPMMSZ-OWOJBTEDSA-N Trans-resveratrol Chemical compound C1=CC(O)=CC=C1\C=C\C1=CC(O)=CC(O)=C1 LUKBXSAWLPMMSZ-OWOJBTEDSA-N 0.000 claims description 2
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims description 2
- 235000013793 astaxanthin Nutrition 0.000 claims description 2
- MQZIGYBFDRPAKN-ZWAPEEGVSA-N astaxanthin Chemical compound C([C@H](O)C(=O)C=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)[C@@H](O)CC1(C)C MQZIGYBFDRPAKN-ZWAPEEGVSA-N 0.000 claims description 2
- 229940022405 astaxanthin Drugs 0.000 claims description 2
- 239000001168 astaxanthin Substances 0.000 claims description 2
- 235000010354 butylated hydroxytoluene Nutrition 0.000 claims description 2
- 229940095259 butylated hydroxytoluene Drugs 0.000 claims description 2
- 239000002738 chelating agent Substances 0.000 claims description 2
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 claims description 2
- 230000001815 facial effect Effects 0.000 claims description 2
- 239000008267 milk Substances 0.000 claims description 2
- 235000013336 milk Nutrition 0.000 claims description 2
- 210000004080 milk Anatomy 0.000 claims description 2
- 238000002156 mixing Methods 0.000 claims description 2
- 239000003002 pH adjusting agent Substances 0.000 claims description 2
- 235000021283 resveratrol Nutrition 0.000 claims description 2
- 229940016667 resveratrol Drugs 0.000 claims description 2
- 239000001509 sodium citrate Substances 0.000 claims description 2
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 2
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 claims description 2
- 229940042585 tocopherol acetate Drugs 0.000 claims description 2
- 239000000376 reactant Substances 0.000 claims 2
- 230000005260 alpha ray Effects 0.000 claims 1
- 150000001408 amides Chemical class 0.000 claims 1
- 238000010894 electron beam technology Methods 0.000 claims 1
- 210000005036 nerve Anatomy 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 abstract description 16
- 230000002335 preservative effect Effects 0.000 abstract description 16
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- 238000001556 precipitation Methods 0.000 abstract description 3
- 230000000052 comparative effect Effects 0.000 description 26
- 239000000047 product Substances 0.000 description 17
- ATUOYWHBWRKTHZ-UHFFFAOYSA-N Propane Chemical compound CCC ATUOYWHBWRKTHZ-UHFFFAOYSA-N 0.000 description 14
- 230000000844 anti-bacterial effect Effects 0.000 description 14
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 8
- 210000004027 cell Anatomy 0.000 description 8
- 230000000694 effects Effects 0.000 description 8
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 description 8
- 229910000041 hydrogen chloride Inorganic materials 0.000 description 8
- 238000000034 method Methods 0.000 description 8
- 230000000813 microbial effect Effects 0.000 description 8
- 239000001294 propane Substances 0.000 description 7
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 6
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 description 6
- 150000005208 1,4-dihydroxybenzenes Chemical class 0.000 description 5
- 244000005700 microbiome Species 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 description 4
- 102000004190 Enzymes Human genes 0.000 description 4
- 108090000790 Enzymes Proteins 0.000 description 4
- CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 description 4
- 229940106189 ceramide Drugs 0.000 description 4
- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 description 4
- 238000005260 corrosion Methods 0.000 description 4
- VVGIYYKRAMHVLU-UHFFFAOYSA-N newbouldiamide Natural products CCCCCCCCCCCCCCCCCCCC(O)C(O)C(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC VVGIYYKRAMHVLU-UHFFFAOYSA-N 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- 238000001291 vacuum drying Methods 0.000 description 4
- 201000004624 Dermatitis Diseases 0.000 description 3
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 206010030113 Oedema Diseases 0.000 description 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
- 125000003545 alkoxy group Chemical group 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-O ammonium group Chemical group [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 3
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- 238000009835 boiling Methods 0.000 description 3
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- VYLVYHXQOHJDJL-UHFFFAOYSA-K cerium trichloride Chemical compound Cl[Ce](Cl)Cl VYLVYHXQOHJDJL-UHFFFAOYSA-K 0.000 description 3
- QYDYPVFESGNLHU-UHFFFAOYSA-N elaidic acid methyl ester Natural products CCCCCCCCC=CCCCCCCCC(=O)OC QYDYPVFESGNLHU-UHFFFAOYSA-N 0.000 description 3
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- QYDYPVFESGNLHU-KHPPLWFESA-N methyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC QYDYPVFESGNLHU-KHPPLWFESA-N 0.000 description 3
- 229940073769 methyl oleate Drugs 0.000 description 3
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- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical compound NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 description 2
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- UKLDJPRMSDWDSL-UHFFFAOYSA-L [dibutyl(dodecanoyloxy)stannyl] dodecanoate Chemical compound CCCCCCCCCCCC(=O)O[Sn](CCCC)(CCCC)OC(=O)CCCCCCCCCCC UKLDJPRMSDWDSL-UHFFFAOYSA-L 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- HFBMWMNUJJDEQZ-UHFFFAOYSA-N acryloyl chloride Chemical compound ClC(=O)C=C HFBMWMNUJJDEQZ-UHFFFAOYSA-N 0.000 description 2
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- YIOJGTBNHQAVBO-UHFFFAOYSA-N dimethyl-bis(prop-2-enyl)azanium Chemical class C=CC[N+](C)(C)CC=C YIOJGTBNHQAVBO-UHFFFAOYSA-N 0.000 description 1
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- YWFWDNVOPHGWMX-UHFFFAOYSA-N n,n-dimethyldodecan-1-amine Chemical compound CCCCCCCCCCCCN(C)C YWFWDNVOPHGWMX-UHFFFAOYSA-N 0.000 description 1
- FATBGEAMYMYZAF-UHFFFAOYSA-N oleicacidamide-heptaglycolether Natural products CCCCCCCCC=CCCCCCCCC(N)=O FATBGEAMYMYZAF-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/604—Alkylpolyglycosides; Derivatives thereof, e.g. esters
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- A61K8/0208—Tissues; Wipes; Patches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
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Abstract
A kind of acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue, it includes wet tissue body and wet tissue liquid, wherein, wet tissue body be have selected with antimicrobial membranes or the non-woven fabrics of nano particle with positive charge, and the antimicrobial membranes or nano particle are formed by chemical bonds；Wet tissue liquid selective RO purified waters, 12 18 alkyl glucosides, lecithin or hydrolecithin, 1,2 pentanediols, skin conditioning agent, other additives, then 0.1 1.0mg/L ozone concentration is passed through in wet tissue liquid, finally, wet tissue liquid is added to wet tissue body by certain weight ratio, pack, that is, form a kind of acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue.The product belongs to the wet tissue of zero precipitation preservative, soft to skin, non-stimulated, without allergy, especially suitable for allergy skin, the tender skin of children etc..
Description
Technical field
The present invention relates to a kind of acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue, more particularly to a kind of infant's hip pad are wet
Towel.
Background technology
In recent years, because the application of wet tissue brings convenience to the life of people, it is increasingly becoming in people's life
Necessity, therefore annual production and the consumption rapid growth of wet tissue, along with the application field of wet tissue constantly expands, accordingly
The exploitation of product requires also more and more higher.At present, wet tissue species is relatively more, there is hand mouth wet tissue, wet sanitary napkins, makeup-removing wet tissue, clean
Skin wet tissue etc., with the lasting expansion of market scale, national industrial policies encourage wet tissue industry to high-tech, high added value
The line of production develops, and improves product competitiveness and the market share, therefore the exploitation of wet tissue formula technique will play important work
With.
Wet tissue preservative is the topic that consumer especially pays close attention to, and most preservative is all by being connect with cell membrane
After touch, with some components of cell membrane, mainly with albumen qualitative response, protection structure or the interference for destroying microbial cell are thin
The metabolism of born of the same parents, the normal growth order of cell is influenceed, so as to reach corrosion-resistant purpose, cation then mainly passes through shadow
Its osmotic pressure is rung, makes membranolysis, contraction and dehydration, so as to be sterilized.Mainly there are 3 kinds of modes：1) microorganism egg is made
Leucismus or solidification, there is substantial amounts of protein in microbial body, all factors that can destroy protein spatial configuration, can make egg
White matter is denatured or solidification.2) enzyme system of microorganism is disturbed, the effect of microorganism endocellular enzyme is relevant with its active group, all energy
Change or destroy the material of intracellular enzyme activities group function, can suppress the activity of microbial enzyme.3) the logical of cell membrane is changed
After permeability, cationic surfactant and phenols act on microorganism, membrane structure can be changed, its normal function is disturbed, enter
It is and dead.
Preservative species used in China's wet tissue industry is various at present, wherein the overwhelming majority is chemical preservative, chemistry
Preservative is because its is simple in construction, the mechanism of action is apparent, property is stable, has a broad antifungal spectrum, cheap and deep liked by wet tissue producer
Love.In fact, some people have found mysterious phenomenon, the addition of same preservative in the user of preservative
It has been several times several years ago, the putrid and deteriorated phenomenon of product has still occurred, most of is because certain a kind of (kind) sterilization and anticorrosion
Agent is used continuously and causes flora to reduce the sensitiveness of the bactericide for a long time, and so as to cause antisepsis and sterilization effect to decline, this is just
It is the resistance to the action of a drug of the so-called microorganism to sterilization antiseptic, also easily causes allergy to consumer skin in this case, stimulates
Situations such as.But with the reach of science, the continuous improvement of consumer safety consciousness and the growing interest to health, people
Gradually find that the chemical preservative in wet tissue can produce ill-effect to human body, therefore the requirement that wet tissue preservative uses also is got over
Come higher, promote wet tissue industry to begin look for the alternative route of chemical preservative, to reduce the injury to consumer skin.And
Traditional chemical preservative can not meet " green ", " health " idea that people pursue, and natural antiseptic agent and preservative free
Appearance compensate for this part vacancy just, therefore study and use non-stimulated, safe chemical preservative substitute
Have become a kind of trend in current daily use chemicals industry.
CN103566371A discloses a kind of antimicrobial method, and it is by the bi-quaternary ammonium salt of lower formula (I)：(R1R2R3N+
X-) wherein, each R1 independently is C8-18 alkyl, C8-18 alkenyls or C8-18 alkynyls to-R5- (R1R2R3N+X-) (I)；Each
R2 and R3 independently is methyl or ethyl；R5 is C3-10 alkylidenes, and it is in β-position or more distant positions by three (C1-3 alkoxies)
Siloxy or the substitution of three (C1-3 alkoxies) silicyl-C1-6 alkoxies；It independently is pharmaceutically acceptable with each X- to contend with
Anion, being applied to needs to form antimicrobial membranes on antimicrobial body surface.The physics antimicrobial membranes, can be extensive
For the mould proof of every profession and trade, antibacterial, deodorization, new combination articles, such as paper can be also combined to form with the product of these industries
Industry, face tissue, hygenic towelette, dixie cup etc..But the wet tissue obtained with this method still has the problem of separating out preservative, antibacterial
Performance need to be improved, and comfortableness also has much room for improvement.
CN101716359A discloses a kind of bactericidal disinfectant material, and it is will to carry capture bacterium, disease by graft process
The compound of the functional group of poison is fixed on nonwoven fabric surface with chemical bond, and the compound includes quaternary ammonium salt, sulfur-bearing chemical combination
Thing, containing the one or more in sulfoacid compound.The bactericidal disinfectant material can be widely used in sterilizing product,
Such as wet towel, cotton balls, sterilization infantees.
CN 106726636A disclose a kind of physical antibacterial wet tissue, and it grafts on bi-quaternary ammonium salt by x ray irradiation x wet
On towel body, antibiotic property, soft and smooth property and the less antibacterial wet tissue of excitant have been obtained.But above-mentioned graft reaction connects
Branch rate, and the wet tissue need further to be lifted in antibiotic property, flexibility and excitant.
In order to solve wet tissue antibiotic property, flexibility difference in the prior art and have irritating problem, the present invention provides
A kind of acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue, its act on be by positively charged antimicrobial membranes or particle with
Negatively charged microbial cell film produces electrostatic force and causes the rupture of microbial cell film or morphologic change and cause micro- life
Thing is dead, and so as to be provided with anti-corrosive antibacterial ability, the product strong antibacterial, flexibility is good, soft to skin, non-stimulated,
Without allergy, especially suitable for allergy skin, the tender skin of children etc..
The content of the invention
The invention provides a kind of acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue.The wet tissue includes wet tissue body and wet
Towel liquid, wet tissue body have selected with antimicrobial membranes or the non-woven fabrics of nano particle with positive charge, and this is antimicrobial
Film or nano particle are formed by chemical bonds；Wet tissue liquid selective RO purified waters, surfactant, emollient, guarantor
Humectant, skin conditioning agent, other additives, 0.1-1.0mg/L ozone concentration is then passed through in wet tissue liquid, finally,
Wet tissue liquid is added to wet tissue body by certain weight ratio, packed, that is, forms a kind of acrylic acid bi-quaternary ammonium salt grafting
Wet nonwoven towel.
Specifically, the invention provides a kind of acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue, it is by wet tissue body and wet
Towel liquid forms, and the wet tissue body is the non-woven fabrics for being bonded high molecular quaternary；The wet tissue liquid is with weight by following
Measure each component composition of percentage：
RO purified waters 65-70%
12-18 alkyl glucosides 0.2-0.8%
Lecithin or hydrolecithin 0.3-0.8%
1,2- pentanediol 25-30%
Skin conditioning agent 0.2-2%
Other additives 1-6%,
Each component content sum is 100%；
Wherein, the preparation method of wet tissue body is：
(1) length is used as 40-50mm, and a diameter of 0.04-0.1mm bamboo pulp fiber is as raw material, through cross lapping water
Bamboo pulp non-woven fabrics is made after piercing technique, the nonwoven carrier that thickness is 3-5mm is obtained after clipped, high-temperature sterilization；
(2) nonwoven carrier made from step (1) is placed in the monomer solution of isopropanol/water mixed solvent preparation, room
Temperature lower lucifuge immersion 12-24 hours；
(3) under nitrogen protection, CeCl is added in monomer solution3/ HCl/water solution, with x ray irradiation x above-mentioned steps
(2) in it is soaking after obtained non-woven fabrics, irradiation intensity 80-200KGy；
(4) after irradiation terminates, unreacted monomer and homopolymer are fallen in extracting, and wet tissue body is obtained after drying；
Wherein, the acrylic acid that monomer is bi-quaternary ammonium salt and degree of neutralization is 60-70%, bi-quaternary ammonium salt in monomer solution
Mass fraction is 0.1-0.2%, and the mol ratio of bi-quaternary ammonium salt and (acrylic acid+acrylates) is (20-30): 1；CeCl3
Initial concentration in reaction system is (1-2) × 10-4The initial concentration of mol/L, HCl in reaction system is (1-2) × 10- 3mol/L；
Wherein, the bi-quaternary ammonium salt is the compound shown in formula 1 or formula 2：
The skin conditioning agent is one in ceramide, Co-Q10, tocopherol acetate, resveratrol, astaxanthin
Kind is a variety of；
Other described additives are one or more kinds of mixing in antioxidant, chelating agent, pH adjusting agent
Thing, the one kind being chosen in particular from Butylated Hydroxytoluene, EDTA-2Na, EDTA-4Na, arginine, citric acid, sodium citrate or it is a kind of with
On mixture.
The 12-18 alkyl glucosides are lauryl glucoside or octadecyl glucoside.
Present invention also offers a kind of preparation method of wet tissue liquid, it is characterised in that wet tissue liquid is transparent and stable
Facial treatment milk, this method comprise the following steps：
(1) 12-18 alkyl glucosides 0.2-0.8%, lecithin or hydrolecithin 0.3-0.8% are mixed and heated
To 50-80 DEG C, at this temperature, 5-20min is quickly stirred, to obtaining clear solution A；
(2) RO purified waters 65-70%, 1,2- pentanediols 25-30%, other additives 1-6% are mixed and heated to
60-90 DEG C, it is evenly stirred until clear solution B；
(3) under high-speed stirred, B solution is slowly added in solution A, until obtaining clear solution C；
(4) C solution that cools addition skin conditioning agent 0.2-2%, stirs to less than 45 DEG C and is made clear solution
D；
(5) ozone is passed through in solution D, ozone concentration is maintained in the range of 0.1-1.0mg/L, produces wet tissue liquid E.
Further, present invention also offers a kind of preparation method of acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue, its
It is characterised by adding the ratio of wet tissue liquid E and the wet tissue body by weight 1.5: 1-4: 1 for being cut into suitable dimension, then
Pack, produce acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue.
Compared with traditional wet tissue, the wet tissue has the following advantages that：
1st, traditional wet tissue is that antiseptic is fixed in non-woven fabrics using adhesive, and the wet tissue is by stable change
Bond is learned together in non-woven fabrics, thus is the product of zero precipitation preservative；
2nd, traditional wet tissue anti-corrosion function is the new old generation of protection structure by destroying microbial cell or interference cell
Thank, influence the normal growth order of cell, so as to reach corrosion-resistant purpose.And the wet tissue anti-corrosion function is by positively charged
Antimicrobial membranes or nano particle and negatively charged microbial film make the rupture of microbial cell film dead by electrostatic force
Die, so as to reach anti-corrosive antibacterial function.
4th, chemical preservation antiseptic wet tissue imposes on human body surface for a long time may cause the symptoms such as human allergy, make as excessive
With may result in dermatitis, spot, or even DNA damage can be caused.In addition, during production, variation bacterium or tolerance are also easily grown
Bacterium, the security risk problem that can not be estimated is added for company, and the application of the wet tissue completely avoid above-mentioned unfavorable factor.
5th, by making specific bi-quaternary ammonium salt under CeCl3/HCl initiation systems and acrylic acid-grafted on wet tissue body,
The grafting rate of bi-quaternary ammonium salt is improved, only excellent antibacterial effect is can reach with seldom amount of monomer, makes the antibacterial of the wet tissue
Effect has exceeded common antibacterial wet tissue of the prior art, and wet tissue has splendid flexibility, uses extremely gentle
And it is nonirritant, drug resistance will not be produced, available for infant's hip pad wet tissue, infant's hand mouth wet tissue, clean skin wet tissue and is defended
Raw wet tissue etc., the wet tissue can be acted rapidly to skin problems such as dermatitis, eczema, bedsore, the red hip of baby, have suppression
Bacterium is antipruritic, the positive effect of skin care, is particularly suitable for using during the red hip of baby.
Brief description of the drawings
Fig. 1 is the nuclear magnetic spectrogram of bi-quaternary ammonium salt A described in preparation example 1.
Fig. 2 is the nuclear magnetic spectrogram of bi-quaternary ammonium salt B described in preparation example 2.
Embodiment
Preparation example 1：
1) dry hydrogen chloride gas is imported in the anhydrous ether solution of octadecyldimethyl tertiary amine, produces white
Precipitation.Then using water as solvent, epoxychloropropane is placed in dropping funel, starts to be slowly added dropwise, 35min is dripped off, at room temperature
After stirring, 12h is reacted in 80 DEG C, determines reaction end by titrating epoxychloropropane quaternary ammonium salt content, reaction finishes
Afterwards, rotary evaporation removes solvent at room temperature, obtains faint yellow paste residue, with acetone recrystallization paste residue, waits to analyse
Go out to depressurize after crystal and filter, be so repeated several times, finally white powder mono-quaternaries product --- (3- is chloro- by intermediate product N-
2- hydroxypropyls)-N, N- dimethyl stearyl ammonium chlorides.Wherein, octadecyldimethyl tertiary amine: hydrogen chloride: epoxychloropropane
Mol ratio be 1.5: 1.2: 1.
2) N, N- dimethyl -1,2- are sequentially added in the four-hole boiling flask equipped with electric mixer, thermometer and still
Ethylenediamine, methyl oleate, dibutyl tin dilaurate, hydroquinones, 110 DEG C are warming up to, back flow reaction 4 hours.Then will be anti-
Answer device to be changed to distilling apparatus, continue to stir, be distilled off at the reaction temperatures unreacted methyl oleate and its with methanol
Azeotropic mixture.Stop reaction, be evaporated under reduced pressure, vacuum drying obtains oleoyl ethyldimethyl amine.Wherein, N, N- dimethyl -1,2-
The mol ratio of ethylenediamine and methyl oleate is 1: 4, and dibutyl tin dilaurate, the dosage of hydroquinones are respectively that reaction solution is total
The 2% of quality and 0.1%.
3) gained in step 1) is sequentially added in the four-hole boiling flask equipped with electric mixer, thermometer and still to produce
Thing I, acetone and hydroquinones.Heating water bath adds step 2) products therefrom II to 60 DEG C, reacts 4 hours.It is molten to filter removing
Agent, unreacted raw material and hydroquinones, crystallisation by cooling, filter to obtain product III.With acetone recrystallization 3-4 times, vacuum drying.
Wherein, product I and II mol ratio is 1: 4, and the dosage of hydroquinones is the 0.15% of reaction solution gross mass
4) gained in step 3) is sequentially added in the four-hole boiling flask equipped with electric mixer, thermometer and still to produce
Thing III, 3- chloropropyl alcohol, is warming up to 160 DEG C, reacts 12h under the conditions of being stirred at reflux, and is evaporated under reduced pressure and removes residue, and then 40
DEG C vacuum drying 10h, produce product IV.
5) products therefrom IV in step 4) is placed in flask, addition dichloromethane is solvent, and triethylamine is used as and ties up acid
Agent, acryloyl chloride is added dropwise under the conditions of ice-water bath, 30min is dripped off, and recession fall ice water-bath is added dropwise, temperature is warmed to room temperature
Lucifuge is reacted 12 hours afterwards, and gained mixture is filtered, and filtrate rotary evaporation removes solvent, and 40 DEG C of vacuum drying 24h are produced down
Bi-quaternary ammonium salt A described in formula.Wherein the mol ratio of product IV, acryloyl chloride and triethylamine is 1: 3: 4.
Preparation example 2：
It is identical with preparation example 1, differ only in：The anhydrous second of Dodecyl Dimethyl Amine is used in the 1) step
Ethereal solution, finally give bi-quaternary ammonium salt B described in following formula.
Embodiment 1
The preparation method of wet tissue body is：
(1) length is used as 50mm, and a diameter of 0.08mm bamboo pulp fiber is as raw material, through cross lapping water jet process
Bamboo pulp non-woven fabrics is made afterwards, the nonwoven carrier that thickness is 4mm is obtained after clipped, high-temperature sterilization；
(2) nonwoven carrier made from step (1) is placed in the monomer solution of 1L isopropanol/waters mixed solvent preparation,
Lucifuge is soaked 24 hours at room temperature；The propylene that monomer is bi-quaternary ammonium salt A and the degree of neutralization neutralized with potassium hydroxide is 65%
Acid, bi-quaternary ammonium salt A mass fraction is 0.1% in monomer solution, and bi-quaternary ammonium salt A and (acrylic acid+acrylates) mole
Than for 25: 1, the volume ratio of isopropanol and water is 3: 1；
(3) under nitrogen protection, CeCl is added in monomer solution3/ HCl/water solution, with gamma-ray irradiation above-mentioned steps
(2) in it is soaking after obtained non-woven fabrics, irradiation intensity 80KGy；CeCl3Initial concentration in reaction system is 2 × 10-4The initial concentration of mol/L, HCl in reaction system is 1 × 10-3mol/L；
(4) after irradiation terminates, unreacted monomer and homopolymer are fallen in extracting, and wet tissue body is obtained after drying；
In wet tissue liquid E preparation technology, solution A selects lauryl glucoside 0.2g, lecithin 0.3g.Solution B is selected
1,2- pentanediol 25g, EDTA-2Na 6g, RO purified water 66.5g.Skin conditioning agent selects water-soluble Cer NS g.
Specially：
1) Dodecyl Polyglucosides 0.2g, lecithin 0.3g are mixed and heated to 60 DEG C, at this temperature, quickly stirred
15min is mixed, to obtaining clear solution A.
2) 1,2- pentanediols 25g, EDTA-2Na 6g, RO purified water 66.5g is mixed and heated to 70 DEG C, stirred
To clear solution B.
3) under high-speed stirred, B solution is slowly added in solution A, until clear solution C is obtained,
4) C solution that cools adds water-soluble Cer NS g to 40 DEG C, stirs and is made clear solution D.
5) ozone is passed through in solution D, ozone concentration is maintained at 0.3mg/L, produces wet tissue liquid E.
The ratio of above-mentioned wet tissue liquid E and wet tissue body by weight 4: 1 is added, then packs, produces acrylic acid
Bi-quaternary ammonium salt grafted nonwoven fabric wet tissue.
Embodiment 2
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except bi-quaternary ammonium salt A is replaced with into obtained bi-quaternary ammonium salt B in preparation example 2.
Embodiment 3
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except bi-quaternary ammonium salt A mass fraction is replaced with into 0.2%.
Embodiment 4
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except bi-quaternary ammonium salt A mass fraction is replaced with into 0.15%.
Embodiment 5
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except the mol ratio of bi-quaternary ammonium salt A and (acrylic acid+acrylates) is replaced with into 20: 1.
Embodiment 6
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except the mol ratio of bi-quaternary ammonium salt A and (acrylic acid+acrylates) is replaced with into 30: 1.
Embodiment 7
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except gamma-rays is replaced with into ultraviolet.
Embodiment 8
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
Identical, except soak time is replaced with 12 hours, irradiation intensity replaces with 200KGy.
Embodiment 9
The preparation method and embodiment 2 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
Identical, except lauryl glucoside is replaced with into octadecyl glucoside, lecithin replaces with hydrolecithin.
Embodiment 10
The preparation method and embodiment 2 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except ozone concentration is maintained at into 1.0mg/L.
Embodiment 11
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except the ratio of wet tissue liquid E and wet tissue body by weight 1.5: 1 is added.
Embodiment 12
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
Identical, except the dosage of lauryl glucoside is replaced with into 0.8g, the dosage of lecithin replaces with 0.8g, 1,2- pentanediol
Dosage replaces with 30g, and EDTA-2Na dosage replaces with 1g, RO purified waters 67.2g, and the dosage of water-soluble ceramide is replaced
For 0.2g.
Embodiment 13
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
Identical, except the dosage of lauryl glucoside is replaced with into 0.5g, the dosage of lecithin replaces with 0.6g, 1,2- pentanediol
Dosage replaces with 28g, and EDTA-2Na dosage replaces with 3g, RO purified waters 66.9g, and the dosage of water-soluble ceramide is replaced
For 1g.
Comparative example 1
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except bi-quaternary ammonium salt A mass fraction is replaced with into 0.05%.
Comparative example 2
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except monomer is only bi-quaternary ammonium salt A.
Comparative example 3
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except being added without CeCl3/ HCl/water solution.
Comparative example 4
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except bi-quaternary ammonium salt A is replaced with into dimethyldiallylammonium salt.
Comparative example 5
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except bi-quaternary ammonium salt A is replaced with into N- methylacryoyloxyethyls-N, N- dimethylammonium-α-N- methyl carboxybetaines.
Comparative example 6
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except bi-quaternary ammonium salt A is replaced with into oleamide Ethyldimethylaminopropyl methyl dimethoxysilane quaternary ammonium salt.
Comparative example 7
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except bi-quaternary ammonium salt A is replaced with into 2- triethoxysilicanes propane Oxy-1-octadecylene base-3- octadecyldimethyl ammoniums
Propane dichloride.
Comparative example 8
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except bi-quaternary ammonium salt A is replaced with into 2- triethoxysilicanes propane Oxy-1-octenyl-3- octadecyldimethyls ammonium third
Alkane dichloride.
Comparative example 9
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except bi-quaternary ammonium salt A is replaced with into 2- triethoxysilicanes propane Oxy-1-laurylene base-3- octadecyldimethyl ammoniums
Propane dichloride.
Comparative example 10
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except bi-quaternary ammonium salt A is replaced with into 2- triethoxysilicane propane Oxy-1-N, N- Dimethylacryloyl-3- octadecanes
Base dimethylammonium propane dichloride.
Comparative example 11
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except bi-quaternary ammonium salt A is replaced with into 2- triethoxysilicane propane Oxy-1-N, N- Dimethylacryloyl-3- dodecanes
Base dimethylammonium propane dichloride.
Comparative example 12
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except monomer solution is replaced with into 2- triethoxysilicane propane Oxy-1-N, the N- dimethyl that mass fraction is 0.1%
The solution of acryloyl group -3- octadecyldimethyl ammonium propane dichloride.
Comparative example 13
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except monomer solution is replaced with into 2- triethoxysilicane propane Oxy-1-N, the N- dimethyl that mass fraction is 0.1%
The solution of acryloyl group -3- dodecyl dimethyl ammonium propane dichloride.
Comparative example 14
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except 1,2- pentanediols are replaced with into 1,5-PD.
Comparative example 15
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except 1,2- pentanediols are replaced with into 1,2-PD.
Comparative example 16
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
Identical, except the dosage of 1,2- pentanediols is replaced with into 22g, the dosage of RO purified waters replaces with 69.5g.
Comparative example 17
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
Identical, except the dosage of 1,2- pentanediols is replaced with into 33g, the dosage of RO purified waters replaces with 65g, EDTA-2Na dosage
1g is replaced with, the dosage of water-soluble ceramide replaces with 0.5g.
Comparative example 18
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except lecithin is replaced with into lanolin.
Comparative example 19
The preparation method and embodiment 1 of wet tissue body, wet tissue liquid E and acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue
It is identical, except lauryl glucoside is replaced with into sodium cocoyl glutamate.
Technique effect：
1. fungistatic effect
By the evaluation criterion testing example in Disposable Sanitary Accessory sanitary standard GB15979-2002 appendix Cs
It is as shown in table 1 with the bacteriostasis rate of wet tissue in comparative example, test result：
The fungistatic effect of the wet tissue of table 1
It can be seen from the data in table 1 compared with the wet tissue in comparative example, wet tissue product of the invention has more excellent
Different anti-microbial property.
2. soft and smooth property
Group is evaluated using 5 people to evaluate the flexibility of wet tissue in embodiment and comparative example by ten point system, test knot
Fruit is as shown in table 2：
The soft and smooth property of the wet tissue of table 2
It can be seen from the data in table 2 compared with the wet tissue in comparative example, wet tissue product of the invention has more excellent
Different softness and smoothness.
3. excitant
Foundation《Disinfection technology standard》In an intact skin stimulation test to wet tissue carry out skin irritation detection, survey
Test result is as shown in table 3：
The excitant of the wet tissue of table 3
Standards of grading：
Erythema is formed：0 is nothing, and 1 is visible reluctantly, and 2 be obvious, and 3 be serious, and 4 be aubergine erythema, and has eschar；
Oedema is formed：0 is nothing, and 1 is visible reluctantly, and 2 be cutaneous protuberance, and profile understands, 3 be that oedema swells about 1mm, and 4 are
Oedema is swelled more than 1mm.
It can be seen from the data in table 3 compared with the wet tissue in comparative example 4-19, wet tissue product of the invention has
Smaller excitant.
4. comfort level
Wet tissue in above-described embodiment and comparative example is used 10 days to red hip baby, the effect such as institute of table 4 after use
Show：
The red hip baby of table 4 uses wet tissue effect
It can be seen from the data in table 4 compared with the wet tissue in comparative example, use the present invention's to red hip baby
After physical antibacterial pasteurization towelette, sufferer improves significantly, suitable for popularization and application.
Claims (10)
1. a kind of acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue, it is made up of wet tissue body and wet tissue liquid, the wet tissue sheet
Body is the non-woven fabrics for being bonded high molecular quaternary；The wet tissue liquid is made up of following with each component of percentage by weight：
RO purified waters 65-70%
12-18 alkyl glucosides 0.2-0.8%
Lecithin or hydrolecithin 0.3-0.8%
1,2- pentanediol 25-30%
Skin conditioning agent 0.2-2%
Other additives 1-6%,
Each component content sum is 100%；
Wherein, the preparation method of wet tissue body is：
(1) length is used as 40-50mm, and a diameter of 0.04-0.1mm bamboo pulp fiber is as raw material, through cross lapping spun lacing work
Bamboo pulp non-woven fabrics is made after skill, the nonwoven carrier that thickness is 3-5mm is obtained after clipped, high-temperature sterilization；
(2) nonwoven carrier made from step (1) is placed in the monomer solution of isopropanol/water mixed solvent preparation, at room temperature
Lucifuge soaks 12-24 hours；
(3) under nitrogen protection, CeCl is added in monomer solution3/ HCl/water solution, passed through with x ray irradiation x above-mentioned steps (2)
The non-woven fabrics obtained after immersion, irradiation intensity 80-200KGy；
(4) after irradiation terminates, unreacted monomer and homopolymer are fallen in extracting, and wet tissue body is obtained after drying；
Wherein, the acrylic acid that monomer is bi-quaternary ammonium salt and degree of neutralization is 60-70%, the quality point of bi-quaternary ammonium salt in monomer solution
Number is 0.1-0.2%, and the mol ratio of bi-quaternary ammonium salt and (acrylic acid+acrylates) is (20-30): 1；CeCl3In reactant
Initial concentration in system is (1-2) × 10-4The initial concentration of mol/L, HCl in reaction system is (1-2) × 10-3mol/L；
The bi-quaternary ammonium salt is the compound shown in formula 1 or formula 2：
2. acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue as claimed in claim 1, wherein, the skin conditioning agent is nerve
One or more in acid amides, Co-Q10, tocopherol acetate, resveratrol, astaxanthin.
3. acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue as claimed in claim 1, wherein, other described additives are antioxygen
One or more kinds of mixtures in agent, chelating agent, pH adjusting agent.
4. the acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue as described in claim 1 or 3, wherein, other additives choosing
From one or more kinds of mixing in Butylated Hydroxytoluene, EDTA-2Na, EDTA-4Na, arginine, citric acid, sodium citrate
Thing.
5. acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue as claimed in claim 1, wherein, the 12-18 alkyl glucosides
For lauryl glucoside.
6. acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue as claimed in claim 1, wherein, the 12-18 alkyl glucosides
For octadecyl glucoside.
7. acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue as claimed in claim 1, wherein, the ray be selected from ultraviolet,
Electron beam, X ray, alpha ray, β rays or gamma-rays.
8. the preparation method of the acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue as described in claim 1-7 any one, it is special
Sign is：
The preparation method of wet tissue body is：
(1) length is used as 40-50mm, and a diameter of 0.04-0.1mm bamboo pulp fiber is as raw material, through cross lapping spun lacing work
Bamboo pulp non-woven fabrics is made after skill, the nonwoven carrier that thickness is 3-5mm is obtained after clipped, high-temperature sterilization；
(2) nonwoven carrier made from step (1) is placed in the monomer solution of isopropanol/water mixed solvent preparation, at room temperature
Lucifuge soaks 12-24 hours；
(3) under nitrogen protection, CeCl is added in monomer solution3/ HCl/water solution, passed through with x ray irradiation x above-mentioned steps (2)
The non-woven fabrics obtained after immersion, irradiation intensity 80-200KGy；
(4) after irradiation terminates, unreacted monomer and homopolymer are fallen in extracting, and wet tissue body is obtained after drying；
Wherein, the acrylic acid that monomer is bi-quaternary ammonium salt and degree of neutralization is 60-70%, the quality point of bi-quaternary ammonium salt in monomer solution
Number is 0.1-0.2%, and the mol ratio of bi-quaternary ammonium salt and (acrylic acid+acrylates) is (20-30): 1；CeCl3In reactant
Initial concentration in system is (1-2) × 10-4The initial concentration of mol/L, HCl in reaction system is (1-2) × 10-3mol/L；
The bi-quaternary ammonium salt is compound shown in formula 1 or formula 2：
Wet tissue liquid is the facial treatment milk of transparent and stable, and its preparation method is：
(1) 12-18 alkyl glucosides 0.2-0.8%, lecithin or hydrolecithin 0.3-0.8% are mixed and heated to 50-
80 DEG C, at this temperature, 5-20min is quickly stirred, to obtaining clear solution A；
(2) RO purified waters 65-70%, 1,2- pentanediols 25-30%, other additives 1-6% are mixed and heated to 60-90
DEG C, it is evenly stirred until clear solution B；
(3) under high-speed stirred, B solution is slowly added in solution A, until obtaining clear solution C；
(4) C solution that cools addition skin conditioning agent 0.2-2%, stirs to less than 45 DEG C and is made clear solution D；
(5) ozone is passed through in solution D, ozone concentration is maintained in the range of 0.1-1.0mg/L, produces wet tissue liquid E；
Finally, the ratio of wet tissue liquid E and the wet tissue body by weight 1.5: 1-4: 1 for being cut into suitable dimension is added, then
Pack, produce acrylic acid bi-quaternary ammonium salt grafted nonwoven fabric wet tissue.
9. preparation method as claimed in claim 8, wherein ozone concentration are in 0.1-0.5mg/L scopes.
10. preparation method as claimed in claim 8, wherein wet tissue liquid E are with being cut into the wet tissue body of suitable dimension by weight
The ratio addition of amount 2: 1-3: 1.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113233995A (en) * | 2021-04-13 | 2021-08-10 | 华南理工大学 | Antibacterial styrene-acrylic emulsion containing biquaternary ammonium salt structure and preparation method and application thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1978501A (en) * | 2006-12-08 | 2007-06-13 | 北京化工大学 | UV-induced polymer surface modifying method |
| CN101716359A (en) * | 2009-12-08 | 2010-06-02 | 北京欧凯纳斯科技有限公司 | Sterilization and pasteurization material and application thereof |
| CN103566371A (en) * | 2012-08-01 | 2014-02-12 | 南京神奇科技开发有限公司 | Antimicrobial physical method |
| CN106038356A (en) * | 2016-07-04 | 2016-10-26 | 苏州宝丽洁日化有限公司 | Physical antibacterial wet wipe and preparation method thereof |
| CN106726636A (en) * | 2017-02-17 | 2017-05-31 | 苏州宝丽洁日化有限公司 | A kind of physical antibacterial wet tissue |
| CN106860029A (en) * | 2017-02-17 | 2017-06-20 | 苏州宝丽洁日化有限公司 | A kind of physical antibacterial wet tissue |
-
2017
- 2017-11-09 CN CN201711094248.9A patent/CN107789214A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1978501A (en) * | 2006-12-08 | 2007-06-13 | 北京化工大学 | UV-induced polymer surface modifying method |
| CN101716359A (en) * | 2009-12-08 | 2010-06-02 | 北京欧凯纳斯科技有限公司 | Sterilization and pasteurization material and application thereof |
| CN103566371A (en) * | 2012-08-01 | 2014-02-12 | 南京神奇科技开发有限公司 | Antimicrobial physical method |
| CN106038356A (en) * | 2016-07-04 | 2016-10-26 | 苏州宝丽洁日化有限公司 | Physical antibacterial wet wipe and preparation method thereof |
| CN106726636A (en) * | 2017-02-17 | 2017-05-31 | 苏州宝丽洁日化有限公司 | A kind of physical antibacterial wet tissue |
| CN106860029A (en) * | 2017-02-17 | 2017-06-20 | 苏州宝丽洁日化有限公司 | A kind of physical antibacterial wet tissue |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113233995A (en) * | 2021-04-13 | 2021-08-10 | 华南理工大学 | Antibacterial styrene-acrylic emulsion containing biquaternary ammonium salt structure and preparation method and application thereof |
| CN113233995B (en) * | 2021-04-13 | 2022-04-05 | 华南理工大学 | Antibacterial styrene-acrylic emulsion containing biquaternary ammonium salt structure and preparation method and application thereof |
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Application publication date: 20180313 |