CN107753904A - A kind of Chinese medicine composition for treating POEMS syndromes and its application - Google Patents
A kind of Chinese medicine composition for treating POEMS syndromes and its application Download PDFInfo
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/40—Cornaceae (Dogwood family)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/804—Rehmannia
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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Abstract
The present invention relates to a kind of Chinese medicine composition for treating POEMS syndromes, by weight, including following raw material：The parts by weight of tag 20 90, the parts by weight of rhizoma zingiberis 10 30, the parts by weight of the Radix Astragali 100 300, the parts by weight of Chinese cassia tree 6 20, the parts by weight of Fructus Corni 15 60, the parts by weight of Poria cocos 15 30 and the parts by weight of cultivated land 10-50 processed.The Chinese medicine composition of the present invention, can effectively treat the POEMS syndromes of patient, a kind of practicable medicine is provided for POEMS syndrome patients.
Description
Technical field
The present invention relates to the field of Chinese medicines, specifically, is related to a kind of Chinese medicine composition for treating POEMS syndromes.
Background technology
POEMS syndromes are the unclear rare multisystem diseases of a kind of cause of disease and pathogenesis, are mainly shown as multiple
Nerve lesion, internal organs enlargement, endocrinopathy, monoclonal gammopathy and skin change.Due to this sick more rare, mesh
Before there is no unified diagnostic criteria.
The content of the invention
The technical problems to be solved by the invention are to provide a kind of Chinese medicine composition for treating POEMS syndromes.
The present invention provides a kind of Chinese medicine composition for treating POEMS syndromes, by weight, including following raw material：System
Tag 20-90 parts by weight, rhizoma zingiberis 10-30 parts by weight, Radix Astragali 100-300 parts by weight, Chinese cassia tree 6-20 parts by weight, Fructus Corni 15-60
Parts by weight, Poria cocos 15-30 parts by weight and the parts by weight of cultivated land 10-50.
The beneficial effects of the present invention are：The Chinese medicine composition of the present invention, it can effectively treat the POEMS synthesis of patient
Sign, a kind of practicable medicine is provided for POEMS syndrome patients.
Wherein, tag processed is with rhizoma zingiberis, Chinese cassia tree：Acrid flavour extremely hot in nature, it is poisonous, there is recuperating depleted yang, the effect of mends fire supporing yang.With
In herein, mainly with warm kidney the yang aspect of yang, yang transforming qi, yang transforming qi are played jointly with rhizoma zingiberis, Chinese cassia tree, yang-energy rises then haze and dissipated, yang-energy
Wen Zeshui can disappear, and yang-energy rises then marrow and can given birth to, and yang-energy rises then god and can supported.Haze dissipates, and removes Wan Chen Cuo, then caused by POEMS syndromes
Marrow can give birth to, essence can answer, and god can be good for, then nervous function can recover, and enlargement organ can reply, and endocrine function can be recovered, M
Type albumen returns normally, and cutaneous pigmentation etc. can be alleviated.
The Radix Astragali matches somebody with somebody Poria cocos：Radix Astragali tonifying Qi, the prosperous then helps yang transforming qi of gas, gas row then water row, then phlegm disappears gas row, gas row then wet row.
With Poria cocos phase 5, a dampness elimination, a tonifying Qi, fortune Middle Palace is good for, then the foundation of acquired constitution can be consolidated.
Fructus Corni matches somebody with somebody cultivated land：Its kidney is mended, its essence is filled out, with strong the congenital foundation.
Further, by weight, the Chinese medicine composition includes following raw material：Parts by weight of tag 40 processed, rhizoma zingiberis 15
Parts by weight, the parts by weight of the Radix Astragali 100, the parts by weight of Chinese cassia tree 20, the parts by weight of Fructus Corni 40, the parts by weight of Poria cocos 20 and the parts by weight of cultivated land 30.
Further, the Chinese medicine composition is oral formulations.
Further, the Chinese medicine composition is water decoction, and its preparation method comprises the following steps：
1) tag 20-90 parts by weight processed are added in the water of 1000 parts by weight after big fire is boiled and be cooked by slow fire 1 hour；
2) addition, rhizoma zingiberis 10-30 parts by weight, Radix Astragali 100-300 parts by weight, Chinese cassia tree 6-20 weight in the decoction in step 1)
Part, Fructus Corni 15-60 parts by weight, Poria cocos 15-30 parts by weight and the parts by weight of cultivated land 10-50 are measured, continue to decoct half an hour, filtering,
Obtain water decoction decoction.
The invention further relates to application of the above-mentioned Chinese medicine composition in POEMS syndromes are treated.
Embodiment
The principle and feature of the present invention are described with reference to embodiments, the given examples are served only to explain the present invention,
It is not intended to limit the scope of the present invention.
The present invention provides a kind of Chinese medicine composition for treating POEMS syndromes, by weight, including following raw material：System
Tag 20-90 parts by weight, rhizoma zingiberis 10-30 parts by weight, Radix Astragali 100-300 parts by weight, Chinese cassia tree 6-20 parts by weight, Fructus Corni 15-60
Parts by weight, Poria cocos 15-30 parts by weight and the parts by weight of cultivated land 10-50.
This prescriptions of traditional Chinese medicine is applied to treat the disease, receives curative effect certainly.Syndrome of decoction ZHEN WU：" Taiyin diseases, sweating, sweating is not
Solution, its people still generated heat, and epigastric throb, a dizzy , Shen Shun is moved, and is shaken and is intended to the ground person that breaks off, Zhen Wu Tang, Decoction for strengthening the Spleen-Yang master it." " shaoyin disease, two or three endlessly, extremely
Four or five, stomachache, difficult urination, four limbs were heavy, diarrhea person, and this is to have aqueous vapor.Its people or cough, or small facility, or lower profit, or
Habitual vomiter, Zhen Wu Tang, Decoction for strengthening the Spleen-Yang master it." from《The Treatise on Fevrile Diseases》The two provisions, there are the heavy, Shen Shun of four limbs to move, nearly falling down due to trembling the characteristics of, this
A little symptom the authors think relevant with the symptom of nervous system, just similar to the nervous symptoms of patient, and have difficult urination
Feature, therefore select the party correct.From POEMS syndrome modern studies, the disease is a kind of rare Clonal thick liquid cell disease of clinic
Disease.Treated for the feature that patient is plasma cell dyscrasias, thus from " marrow ", and marrow is given birth to by kidney, therefore agree with reinforcing kidney.
Wherein, tag processed is with rhizoma zingiberis, Chinese cassia tree：Acrid flavour extremely hot in nature, it is poisonous, there is recuperating depleted yang, the effect of mends fire supporing yang.With
In herein, mainly with warm kidney the yang aspect of yang, yang transforming qi, yang transforming qi are played jointly with rhizoma zingiberis, Chinese cassia tree, yang-energy rises then haze and dissipated, yang-energy
Wen Zeshui can disappear, and yang-energy rises then marrow and can given birth to, and yang-energy rises then god and can supported.Haze dissipates, and removes Wan Chen Cuo, then caused by POEMS syndromes
Marrow can give birth to, essence can answer, and god can be good for, then nervous function can recover, and enlargement organ can reply, and endocrine function can be recovered, M
Type albumen returns normally, and cutaneous pigmentation etc. can be alleviated.
The Radix Astragali matches somebody with somebody Poria cocos：Radix Astragali tonifying Qi, the prosperous then helps yang transforming qi of gas, gas row then water row, then phlegm disappears gas row, gas row then wet row.
With Poria cocos phase 5, a dampness elimination, a tonifying Qi, fortune Middle Palace is good for, then the foundation of acquired constitution can be consolidated.
Fructus Corni matches somebody with somebody cultivated land：Its kidney is mended, its essence is filled out, with strong the congenital foundation.
Further, by weight, the Chinese medicine composition includes following raw material：Parts by weight of tag 40 processed, rhizoma zingiberis 15
Parts by weight, the parts by weight of the Radix Astragali 100, the parts by weight of Chinese cassia tree 20, the parts by weight of Fructus Corni 40, the parts by weight of Poria cocos 20 and the parts by weight of cultivated land 30.
Further, the Chinese medicine composition is oral formulations.
Further, the Chinese medicine composition is water decoction, and its preparation method comprises the following steps：
1) tag 20-90 parts by weight processed are added in the water of 1000 parts by weight after big fire is boiled and be cooked by slow fire 1 hour；
2) addition, rhizoma zingiberis 10-30 parts by weight, Radix Astragali 100-300 parts by weight, Chinese cassia tree 6-20 weight in the decoction in step 1)
Part, Fructus Corni 15-60 parts by weight, Poria cocos 15-30 parts by weight and the parts by weight of cultivated land 10-50 are measured, continue to decoct half an hour, filtering,
Obtain water decoction decoction.
The invention further relates to application of the above-mentioned Chinese medicine composition in POEMS syndromes are treated.
The instructions of taking of water decoction of the Chinese medicine composition of the treatment POEMS syndromes of the present invention is：When taking for the first time,
Take about 20ml on a small quantity, as in mouth without feeling of numbness, then gradual dosage, dosage to the sensation for having tongue fiber crops, then no longer dosage.Later evidence
There is the amount adjustment dosage of tongue feeling of numbness, if the amount of tongue feeling of numbness exceedes 1/3 per dosage, taken by 1/3 amount；
If the amount of feeling of numbness is less than 1/3, untill amount is transferred into appropriateness.
Embodiment 1
Patient 1, man, 49 years old, with POEMS syndromes
The water decoction of the Chinese medicine composition for the treatment of POEMS syndromes of the present invention is taken, three times a day, is taken 2 years,
Review result is shown, neurological functional recovery, can normally be walked；Organ recovers normal；Endocrine function recovers normal；Skin pigment
Calmness takes a turn for the better；More dropsies of serous cavity disappear.Patient is almost recovered.
Embodiment 2
Patient 2, female, 71 years old, with POEMS syndromes
The water decoction of the Chinese medicine composition for the treatment of POEMS syndromes of the present invention is taken, three times a day, takes half
Year, review result is shown, neurological functional recovery, can normally be walked；Organ recovers normal；Endocrine function recovers normal；Skin
Pigmentation takes a turn for the better；More dropsies of serous cavity disappear.Patient is almost recovered.
The foregoing is only presently preferred embodiments of the present invention, be not intended to limit the invention, it is all the present invention spirit and
Within principle, any modification, equivalent substitution and improvements made etc., it should be included in the scope of the protection.
Claims (5)
- A kind of 1. Chinese medicine composition for treating POEMS syndromes, it is characterised in that by weight, including following raw material：Make attached Piece 20-90 parts by weight, rhizoma zingiberis 10-30 parts by weight, Radix Astragali 100-300 parts by weight, Chinese cassia tree 6-20 parts by weight, Fructus Corni 15-60 weights Measure part, Poria cocos 15-30 parts by weight and the parts by weight of cultivated land 10-50.
- A kind of 2. Chinese medicine composition for treating POEMS syndromes according to claim 1, it is characterised in that by weight, Including following raw material：Parts by weight of tag 40 processed, the parts by weight of rhizoma zingiberis 15, the parts by weight of the Radix Astragali 100, the parts by weight of Chinese cassia tree 20, Fructus Corni 40 Parts by weight, the parts by weight of Poria cocos 20 and the parts by weight of cultivated land 30.
- A kind of 3. Chinese medicine composition for treating POEMS syndromes according to claim 1 or claim 2, it is characterised in that the Chinese medicine Composition is oral formulations.
- A kind of 4. Chinese medicine composition for treating POEMS syndromes according to claim 3, it is characterised in that the Chinese medicine group Compound is water decoction, and its preparation method comprises the following steps：1) tag 20-90 parts by weight processed are added in the water of 1000 parts by weight after big fire is boiled and be cooked by slow fire 1 hour；2) added in the decoction in step 1) rhizoma zingiberis 10-30 parts by weight, Radix Astragali 100-300 parts by weight, Chinese cassia tree 6-20 parts by weight, Fructus Corni 15-60 parts by weight, Poria cocos 15-30 parts by weight and the parts by weight of cultivated land 10-50, continue to decoct half an hour, filtering, obtain Water decoction decoction.
- 5. application of any described Chinese medicine compositions of claim 1-4 in POEMS syndromes are treated.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711058263.8A CN107753904B (en) | 2017-11-01 | 2017-11-01 | Traditional Chinese medicine composition for treating POEMS syndrome and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711058263.8A CN107753904B (en) | 2017-11-01 | 2017-11-01 | Traditional Chinese medicine composition for treating POEMS syndrome and application thereof |
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| Publication Number | Publication Date |
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| CN107753904A true CN107753904A (en) | 2018-03-06 |
| CN107753904B CN107753904B (en) | 2020-12-22 |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103301440A (en) * | 2013-07-15 | 2013-09-18 | 刘晓东 | Chinese medicine capable of warming Yang and tonifying kidneys |
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2017
- 2017-11-01 CN CN201711058263.8A patent/CN107753904B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103301440A (en) * | 2013-07-15 | 2013-09-18 | 刘晓东 | Chinese medicine capable of warming Yang and tonifying kidneys |
Non-Patent Citations (2)
| Title |
|---|
| 王宗明等: "从温肾助阳、软坚利水治疗POEMS综合征1例体会", 《内蒙古中医药》 * |
| 陈金亮等: "中药治疗POEMS综合征21例", 《四川中医》 * |
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