CN107753809A - 一种治疗风湿、类风湿及风湿关节肿痛的药物及其制备方法 - Google Patents
一种治疗风湿、类风湿及风湿关节肿痛的药物及其制备方法 Download PDFInfo
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Abstract
本发明公开了一种治疗风湿、类风湿及风湿关节肿痛的药物及其制备方法，该治疗风湿、类风湿及风湿关节肿痛的药物，按重量份计，包括以下原料：虎杖18‑22份、黑骨头18‑22份、鸡血藤18‑22份、小血藤8‑12份、刺五加18‑22份、小木通8‑12份、过山龙4‑6份、金刚藤8‑12份、苧麻8‑12份、木瓜8‑12份、续断8‑12份。其制备方法是各原料药加入4500‑5500份的酒中，浸泡2‑3天，即得。具有起效快、疗效好、安全无毒副作用的特点。临床100例患者使用，总有效率80%。
Description
技术领域
本发明属于中药领域，具体涉及一种治疗风湿、类风湿及风湿关节肿痛的药物，同时还涉及该治疗风湿、类风湿及风湿关节肿痛的药物的制备方法。
背景技术
风湿病是一组侵犯关节、骨骼、肌肉、血管及有关软组织或结缔组织为主的疾病，其中多数为自身免疫性疾病。发病多较隐蔽而缓慢，病程较长，且大多具有遗传倾向。 诊断及治疗均有一定难度；血液中多可检查出不同的自身抗体，可能与不同HLA亚型有关；对非甾类抗炎药(NSAID)，糖皮质激素和免疫抑制剂有较好的短期或长期的缓解性反应。
类风湿关节炎（RA）是一种病因未明的慢性、以炎性滑膜炎为主的系统性疾病。其特征是手、足小关节的多关节、对称性、侵袭性关节炎症，经常伴有关节外器官受累及血清类风湿因子阳性，可以导致关节畸形及功能丧失。
风湿痛指主要侵犯关节、肌肉、骨骼及关节周围的软组织(肌腱、韧带、滑囊、筋膜等部位)的疾病所引起的局部性或全身性疼痛。风湿痛指主要侵犯关节、肌肉、骨骼及关节周围的软组织的疾病所引起的局部性或全身性疼痛。其病症属麻痹症一类，中医认为是风和湿两种病邪结合所致的病症。症见有头痛﹑发热﹑微汗﹑恶风﹑身重﹑小便不利﹑骨节酸痛﹑不能屈伸等。关节病变除有疼痛外尚伴有肿胀和活动障碍，呈发作与缓解交替的慢性病程。由于患者的血液循环不通畅，导致肌肉或者组织所需要的营养无法通过血液循环来输送，致使患者肌肉缺少营养而加速老化变得僵硬，严重的会导致患者肌肉和血管萎缩，部分患者且可出现关节致残和内脏功能衰竭。现代流行病骨质增生、椎间盘突出、风湿关节炎等病越发年轻化和大众化，呈逐年上升趋势。这些病症的共同点都是以疼痛为主症。
目前西医治疗中手术疗法见效快但技术要求高、风险大、费用高。西药主要是激素及镇痛类药，伤肝伤胃且镇痛持续时间短。中药治疗不良反应小，目前市场上的药物不胜理想，大多数的中药成份多，长期服用肝肾负担较重，不适合长期使用。
发明内容
本发明的目的在于提供一种起效快、疗效好、副作用小的治疗风湿、类风湿及风湿关节肿痛的药物。
本发明的另一目的在于提供该治疗风湿、类风湿及风湿关节肿痛的药物的制备方法。
本发明的一种治疗风湿、类风湿及风湿关节肿痛的药物，按重量份计，包括以下原料：
虎杖18-22份、黑骨头18-22份、鸡血藤18-22份、小血藤8-12份、刺五加18-22份、小木通8-12份、过山龙4-6份、金刚藤8-12份、苧麻8-12份、木瓜8-12份、续断8-12份。
上述的一种治疗风湿、类风湿及风湿关节肿痛的药物，按重量份计，优选以下原料：
虎杖20份、黑骨头20份、鸡血藤20份、小血藤10份、刺五加20份、小木通10份、过山龙5份、金刚藤10份、苧麻10份、木瓜10份、续断10份。
上述的一种治疗风湿、类风湿及风湿关节肿痛的药物，其制备方法包括以下步骤：
（1）按重量份取样；
（2）将各原料药加入4500-5500份的酒中，浸泡2-3天，即得。
本发明与现有技术相比，具有明显有益效果，从以上技术方案可知：本发明选用虎杖、黑骨头、鸡血藤、小血藤、刺五加、小木通、过山龙、金刚藤、苧麻、木瓜、续断为原料，通过诸药的协同作用发挥活血通络、祛伤止痛、散风除湿之功效。达到治疗风湿、类风湿及风湿关节肿痛的目的。本发明的药物治疗风湿、类风湿及风湿关节肿痛具有起效快、疗效好、安全无毒副作用的特点。临床100例患者使用，总有效率80%。
具体实施方式
以下通过试验例来进一步阐述本发明所述药物的有益效果。
试验例：本发明药物的临床观察
1、临床资料：
全部病例全部病例100例，其中最大年龄70岁，最小年龄18岁，男53例，女47例。
2、诊断标准：
《中医病症诊断疗效标准》。
3、治疗方法：
口服本发明实施例所得药物，每次25克，每天3次。
4、疗效标准：
显效：症状消失；
有效：症状明显缓解；
无效：症状无明显改善。
5、治疗结果：
100例患者使用本发明药物，显效77例，有效3例，无效20例，显效率77%，总有效率80%。
实施例1
一种治疗风湿、类风湿及风湿关节肿痛的药物的制备方法，包括以下步骤：
（1）称取：虎杖18克、黑骨头22克、鸡血藤18克、小血藤12克、刺五加18克、小木通12克、过山龙4克、金刚藤12克、苧麻8克、木瓜12克、续断8克；
（2）将各原料药加入5500克的酒中，浸泡2天，即得。
实施例2
一种治疗风湿、类风湿及风湿关节肿痛的药物的制备方法，包括以下步骤：
（1）称取：虎杖20克、黑骨头20克、鸡血藤20克、小血藤10克、刺五加20克、小木通10克、过山龙5克、金刚藤10克、苧麻10克、木瓜10克、续断10克；
（2）将各原料药加入5000克的酒中，浸泡2天，即得。
实施例3
一种治疗风湿、类风湿及风湿关节肿痛的药物的制备方法，包括以下步骤：
（1）称取：虎杖22克、黑骨头18克、鸡血藤22克、小血藤8克、刺五加22克、小木通8克、过山龙6克、金刚藤8克、苧麻12克、木瓜8克、续断12克；
（2）将各原料药加入4500克的酒中，浸泡3天，即得。
以上所述，仅是本发明的较佳实施例而已，并非对本发明作任何形式上的限制，任何未脱离本发明技术方案内容，依据本发明的技术实质对以上实施例所作的任何简单修改、等同变化与修饰，均仍属于本发明技术方案的范围内。
Claims (3)
1.一种治疗风湿、类风湿及风湿关节肿痛的药物，按重量份计，包括以下原料：
虎杖18-22份、黑骨头18-22份、鸡血藤18-22份、小血藤8-12份、刺五加18-22份、小木通8-12份、过山龙4-6份、金刚藤8-12份、苧麻8-12份、木瓜8-12份、续断8-12份。
2.如权利要求1所述的一种治疗风湿、类风湿及风湿关节肿痛的药物，按重量份计，包括以下原料：
虎杖20份、黑骨头20份、鸡血藤20份、小血藤10份、刺五加20份、小木通10份、过山龙5份、金刚藤10份、苧麻10份、木瓜10份、续断10份。
3.如权利要求1和2所述的一种治疗风湿、类风湿及风湿关节肿痛的药物，其制备方法包括以下步骤：
（1）按重量份取样；
（2）将各原料药加入4500-5500份的酒中，浸泡2-3天，即得。
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